locus-tag	class	description
FYA48_RS00005	COG0445	tRNA wobble uridine modification
FYA48_RS00010	COG0357	Ribosomal RNA small subunit methyltransferase G
FYA48_RS00015	COG1192	Involved in chromosome partitioning
FYA48_RS00020	COG1475	DNA binding
FYA48_RS00025	COG0252	asparaginase activity
FYA48_RS00045	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FYA48_RS00055	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FYA48_RS00065	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FYA48_RS00070	COG0081	regulation of translation
FYA48_RS00075	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FYA48_RS00080	COG0222	ribosome binding
FYA48_RS00085	COG0085	RNA polymerase activity
FYA48_RS00090	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FYA48_RS00125	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FYA48_RS00130	COG0049	tRNA binding
FYA48_RS00135	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FYA48_RS00140	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FYA48_RS00145	COG0051	transcription antitermination factor activity, RNA binding
FYA48_RS00150	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FYA48_RS00155	COG0088	Forms part of the polypeptide exit tunnel
FYA48_RS00160	COG0089	rRNA binding
FYA48_RS00165	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FYA48_RS00170	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FYA48_RS00175	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FYA48_RS00180	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FYA48_RS00185	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FYA48_RS00190	COG0255	Belongs to the universal ribosomal protein uL29 family
FYA48_RS00195	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FYA48_RS00205	COG4177	L-phenylalanine transmembrane transporter activity
FYA48_RS00215	COG1129	ABC transporter
FYA48_RS00220	COG0411	ABC transporter
FYA48_RS00250	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FYA48_RS00255	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FYA48_RS00260	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FYA48_RS00265	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FYA48_RS00270	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FYA48_RS00275	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FYA48_RS00280	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FYA48_RS00285	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FYA48_RS00290	COG1841	ribosomal large subunit assembly
FYA48_RS00295	COG0200	Binds to the 23S rRNA
FYA48_RS00300	COG0201	protein transport
FYA48_RS00305	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FYA48_RS00310	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FYA48_RS00315	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FYA48_RS00320	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FYA48_RS00325	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FYA48_RS00330	COG0202	RNA polymerase activity
FYA48_RS00335	COG0203	ribosomal protein L17
FYA48_RS00340	COG0537	adenosine 5'-monophosphoramidase activity
FYA48_RS00345	COG1324	tolerance protein
FYA48_RS00350	COG4232	protein-disulfide reductase activity
FYA48_RS00365	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FYA48_RS00375	COG1333	cytochrome c biogenesis protein
FYA48_RS00380	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FYA48_RS00395	COG1965	Belongs to the frataxin family
FYA48_RS00405	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FYA48_RS00410	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FYA48_RS00415	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FYA48_RS00435	COG2814	Major facilitator Superfamily
FYA48_RS00460	COG2801	Transposase and inactivated derivatives
FYA48_RS00490	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FYA48_RS00495	COG2922	Belongs to the Smg family
FYA48_RS00500	COG1629	transport
FYA48_RS00510	COG2358	TRAP transporter, solute receptor (TAXI family
FYA48_RS00520	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FYA48_RS00535	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FYA48_RS00540	COG0183	Belongs to the thiolase family
FYA48_RS00545	COG1960	acyl-CoA dehydrogenase activity
FYA48_RS00570	COG2200	EAL domain
FYA48_RS00575	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FYA48_RS00585	COG0018	arginyl-trna synthetase
FYA48_RS00600	COG0154	amidase activity
FYA48_RS00605	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FYA48_RS00615	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FYA48_RS00625	COG0697	spore germination
FYA48_RS00685	COG3350	monooxygenase activity
FYA48_RS00710	COG1309	transcriptional regulator
FYA48_RS00740	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FYA48_RS00745	COG1280	lysine exporter protein (LysE YggA)
FYA48_RS00750	COG0513	Belongs to the DEAD box helicase family
FYA48_RS00760	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
FYA48_RS00765	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FYA48_RS00795	COG2969	positive regulation of protein catabolic process
FYA48_RS00800	COG0625	glutathione transferase activity
FYA48_RS00805	COG2857	Cytochrome c1
FYA48_RS00810	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FYA48_RS00815	COG0723	plastoquinol--plastocyanin reductase activity
FYA48_RS00820	COG1970	mechanosensitive ion channel activity
FYA48_RS00825	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FYA48_RS00830	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FYA48_RS00840	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FYA48_RS00845	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FYA48_RS00855	COG0140	phosphoribosyl-ATP diphosphatase activity
FYA48_RS00860	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FYA48_RS00865	COG0107	imidazoleglycerol-phosphate synthase activity
FYA48_RS00870	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FYA48_RS00880	COG0131	Imidazoleglycerol-phosphate dehydratase
FYA48_RS00885	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FYA48_RS00890	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FYA48_RS00895	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FYA48_RS00900	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FYA48_RS00910	COG0842	Transport permease protein
FYA48_RS00915	COG1131	(ABC) transporter
FYA48_RS00930	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FYA48_RS00935	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FYA48_RS00940	COG1127	ABC transporter
FYA48_RS00960	COG0067	glutamate synthase
FYA48_RS00960	COG0069	glutamate synthase activity
FYA48_RS00960	COG0070	glutamate synthase
FYA48_RS00985	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FYA48_RS01005	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FYA48_RS01010	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FYA48_RS01055	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FYA48_RS01090	COG0109	protoheme IX farnesyltransferase activity
FYA48_RS01095	COG1999	signal sequence binding
FYA48_RS01115	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FYA48_RS01120	COG2814	Major facilitator Superfamily
FYA48_RS01135	COG1522	sequence-specific DNA binding
FYA48_RS01200	COG4948	Mandelate Racemase Muconate Lactonizing
FYA48_RS01215	COG3119	arylsulfatase activity
FYA48_RS01250	COG0402	S-adenosylhomocysteine deaminase activity
FYA48_RS01260	COG1304	FMN binding
FYA48_RS01265	COG1254	Belongs to the acylphosphatase family
FYA48_RS01275	COG3181	Tripartite tricarboxylate transporter family receptor
FYA48_RS01285	COG1414	Transcriptional regulator
FYA48_RS01305	COG0028	Belongs to the TPP enzyme family
FYA48_RS01310	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FYA48_RS01315	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYA48_RS01320	COG1960	acyl-CoA dehydrogenase activity
FYA48_RS01355	COG3181	Tripartite tricarboxylate transporter family receptor
FYA48_RS01360	COG0583	DNA-binding transcription factor activity
FYA48_RS01375	COG0129	dihydroxy-acid dehydratase activity
FYA48_RS01380	COG2084	Dehydrogenase
FYA48_RS01395	COG1671	Belongs to the UPF0178 family
FYA48_RS01400	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FYA48_RS01410	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FYA48_RS01415	COG0443	Heat shock 70 kDa protein
FYA48_RS01440	COG2169	Transcriptional regulator
FYA48_RS01440	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FYA48_RS01455	COG1683	Conserved Protein
FYA48_RS01460	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FYA48_RS01475	COG1120	ATPase activity
FYA48_RS01480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FYA48_RS01485	COG4558	Periplasmic binding protein
FYA48_RS01490	COG3720	iron ion transport
FYA48_RS01500	COG3712	iron ion homeostasis
FYA48_RS01505	COG1595	DNA-templated transcription, initiation
FYA48_RS01525	COG1607	acyl-coa hydrolase
FYA48_RS01540	COG0437	4 iron, 4 sulfur cluster binding
FYA48_RS01545	COG2864	formate dehydrogenase
FYA48_RS01560	COG3276	selenocysteine insertion sequence binding
FYA48_RS01595	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FYA48_RS01600	COG0512	Glutamine amidotransferase of anthranilate synthase
FYA48_RS01610	COG0546	phosphoglycolate phosphatase activity
FYA48_RS01615	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FYA48_RS01620	COG2967	ApaG domain
FYA48_RS01625	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FYA48_RS01630	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FYA48_RS01635	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FYA48_RS01640	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FYA48_RS01645	COG0037	tRNA processing
FYA48_RS01665	COG1024	Enoyl-CoA hydratase
FYA48_RS01680	COG0356	it plays a direct role in the translocation of protons across the membrane
FYA48_RS01690	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FYA48_RS01695	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FYA48_RS01700	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FYA48_RS01705	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FYA48_RS01710	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FYA48_RS01715	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FYA48_RS01730	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FYA48_RS01735	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FYA48_RS01740	COG0210	DNA helicase
FYA48_RS01755	COG4608	Belongs to the ABC transporter superfamily
FYA48_RS01760	COG0444	Belongs to the ABC transporter superfamily
FYA48_RS01765	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FYA48_RS01790	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FYA48_RS01795	COG1024	Enoyl-CoA hydratase
FYA48_RS01800	COG1024	Enoyl-CoA hydratase
FYA48_RS01805	COG2070	2-Nitropropane dioxygenase
FYA48_RS01820	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYA48_RS01825	COG1250	3-hydroxyacyl-CoA dehydrogenase
FYA48_RS01845	COG2267	carboxylic ester hydrolase activity
FYA48_RS01865	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FYA48_RS01875	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FYA48_RS01875	COG2813	Specifically methylates the guanine in position
FYA48_RS01880	COG2223	nitrite transmembrane transporter activity
FYA48_RS01885	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FYA48_RS01900	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FYA48_RS01905	COG0708	Exodeoxyribonuclease III
FYA48_RS01910	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FYA48_RS01915	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FYA48_RS01920	COG0154	amidase activity
FYA48_RS01925	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FYA48_RS01930	COG1077	Cell shape determining protein MreB Mrl
FYA48_RS01935	COG1792	Involved in formation and maintenance of cell shape
FYA48_RS01945	COG0768	penicillin binding
FYA48_RS01950	COG0772	Belongs to the SEDS family
FYA48_RS01955	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FYA48_RS01960	COG0471	metal ion transport
FYA48_RS01965	COG1309	transcriptional regulator
FYA48_RS01975	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FYA48_RS01990	COG2823	Periplasmic or secreted lipoprotein
FYA48_RS01995	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FYA48_RS02000	COG0792	nuclease activity
FYA48_RS02020	COG1660	Displays ATPase and GTPase activities
FYA48_RS02035	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FYA48_RS02045	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FYA48_RS02055	COG3181	Tripartite tricarboxylate transporter family receptor
FYA48_RS02060	COG1473	amidohydrolase
FYA48_RS02065	COG1137	ATPase activity
FYA48_RS02080	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FYA48_RS02090	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FYA48_RS02110	COG1294	oxidase, subunit
FYA48_RS02120	COG4988	ABC transporter
FYA48_RS02125	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FYA48_RS02130	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FYA48_RS02145	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FYA48_RS02150	COG1238	metal cluster binding
FYA48_RS02160	COG1802	Transcriptional regulator
FYA48_RS02170	COG1984	allophanate hydrolase subunit 2
FYA48_RS02175	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FYA48_RS02185	COG0583	DNA-binding transcription factor activity
FYA48_RS02190	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FYA48_RS02195	COG5002	protein histidine kinase activity
FYA48_RS02200	COG0745	RESPONSE REGULATOR receiver
FYA48_RS02205	COG2226	methyltransferase
FYA48_RS02250	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FYA48_RS02260	COG1028	Short-chain dehydrogenase reductase Sdr
FYA48_RS02280	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FYA48_RS02285	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FYA48_RS02295	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FYA48_RS02315	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FYA48_RS02320	COG1538	Outer membrane efflux protein
FYA48_RS02330	COG0351	phosphomethylpyrimidine kinase
FYA48_RS02335	COG2022	thiamine diphosphate biosynthetic process
FYA48_RS02340	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FYA48_RS02360	COG2226	methyltransferase
FYA48_RS02370	COG1194	a g-specific adenine glycosylase
FYA48_RS02380	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FYA48_RS02385	COG2177	Part of the ABC transporter FtsEX involved in
FYA48_RS02390	COG2884	Cell division ATP-binding protein ftsE
FYA48_RS02395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYA48_RS02400	COG4597	amino acid ABC transporter
FYA48_RS02405	COG0765	amino acid transport
FYA48_RS02410	COG1126	abc transporter atp-binding protein
FYA48_RS02440	COG0477	Major facilitator Superfamily
FYA48_RS02450	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FYA48_RS02455	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FYA48_RS02470	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FYA48_RS02475	COG0237	dephospho-CoA kinase activity
FYA48_RS02480	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
FYA48_RS02490	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FYA48_RS02505	COG3539	Fimbrial protein
FYA48_RS02510	COG3539	Fimbrial protein
FYA48_RS02525	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FYA48_RS02535	COG1846	Transcriptional regulator
FYA48_RS02605	COG1028	Short-chain dehydrogenase reductase Sdr
FYA48_RS02610	COG1024	Enoyl-CoA hydratase
FYA48_RS02615	COG1960	acyl-CoA dehydrogenase activity
FYA48_RS02645	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FYA48_RS02650	COG0352	thiamine-phosphate diphosphorylase activity
FYA48_RS02655	COG0351	phosphomethylpyrimidine kinase
FYA48_RS02665	COG1678	Uncharacterized ACR, COG1678
FYA48_RS02670	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FYA48_RS02695	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FYA48_RS02705	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FYA48_RS02710	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FYA48_RS02720	COG0557	exoribonuclease II activity
FYA48_RS02730	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FYA48_RS02735	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FYA48_RS02740	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FYA48_RS02750	COG0439	Biotin carboxylase
FYA48_RS02755	COG2264	protein methyltransferase activity
FYA48_RS02765	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FYA48_RS02790	COG1696	Membrane protein involved in D-alanine export
FYA48_RS02795	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FYA48_RS02840	COG1522	sequence-specific DNA binding
FYA48_RS02855	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FYA48_RS02920	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FYA48_RS02945	COG3028	Belongs to the UPF0307 family
FYA48_RS02950	COG0312	modulator of DNA gyrase
FYA48_RS02955	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FYA48_RS02960	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FYA48_RS02965	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FYA48_RS02975	COG0316	Belongs to the HesB IscA family
FYA48_RS02985	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FYA48_RS02995	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FYA48_RS03000	COG1881	PFAM PEBP family protein
FYA48_RS03005	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FYA48_RS03010	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FYA48_RS03025	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FYA48_RS03025	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FYA48_RS03040	COG2718	Belongs to the UPF0229 family
FYA48_RS03045	COG2719	SpoVR family
FYA48_RS03105	COG0165	Argininosuccinate lyase
FYA48_RS03110	COG0589	response to stress
FYA48_RS03120	COG2816	NAD+ diphosphatase activity
FYA48_RS03125	COG4993	Dehydrogenase
FYA48_RS03150	COG3181	Tripartite tricarboxylate transporter family receptor
FYA48_RS03155	COG2979	Protein of unknown function (DUF533)
FYA48_RS03160	COG4206	TonB-dependent receptor
FYA48_RS03175	COG0741	lytic transglycosylase activity
FYA48_RS03175	COG1388	LysM domain
FYA48_RS03180	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FYA48_RS03185	COG2226	methyltransferase
FYA48_RS03190	COG0328	RNA-DNA hybrid ribonuclease activity
FYA48_RS03215	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FYA48_RS03235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYA48_RS03240	COG0842	Transport permease protein
FYA48_RS03240	COG1129	ABC transporter
FYA48_RS03245	COG0842	Transport permease protein
FYA48_RS03265	COG0463	Glycosyl transferase, family 2
FYA48_RS03270	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FYA48_RS03285	COG1073	alpha beta
FYA48_RS03295	COG0697	spore germination
FYA48_RS03300	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FYA48_RS03325	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FYA48_RS03355	COG0823	Involved in the tonB-independent uptake of proteins
FYA48_RS03365	COG0848	biopolymer transport protein
FYA48_RS03370	COG0811	peptide transport
FYA48_RS03375	COG0824	Thioesterase
FYA48_RS03380	COG0442	prolyl-tRNA aminoacylation
FYA48_RS03425	COG2084	Dehydrogenase
FYA48_RS03470	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FYA48_RS03475	COG4654	Cytochrome c, class I
FYA48_RS03480	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FYA48_RS03545	COG1473	amidohydrolase
FYA48_RS03550	COG0418	dihydroorotase activity
FYA48_RS03555	COG0488	(ABC) transporter
FYA48_RS03565	COG2001	Belongs to the MraZ family
FYA48_RS03570	COG0275	rRNA processing
FYA48_RS03575	COG3116	cell division
FYA48_RS03585	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FYA48_RS03590	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FYA48_RS03595	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FYA48_RS03605	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FYA48_RS03610	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FYA48_RS03615	COG1181	Belongs to the D-alanine--D-alanine ligase family
FYA48_RS03620	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FYA48_RS03635	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FYA48_RS03650	COG0739	heme binding
FYA48_RS03655	COG0653	protein targeting
FYA48_RS03680	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FYA48_RS03685	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FYA48_RS03695	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FYA48_RS03745	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FYA48_RS03760	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
FYA48_RS03805	COG3181	Tripartite tricarboxylate transporter family receptor
FYA48_RS03810	COG2084	Dehydrogenase
FYA48_RS03820	COG1803	Methylglyoxal synthase
FYA48_RS03820	COG1597	lipid kinase activity
FYA48_RS03830	COG0671	phosphoesterase, PA-phosphatase related
FYA48_RS03850	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FYA48_RS03855	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FYA48_RS03860	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FYA48_RS03865	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FYA48_RS03870	COG0649	NAD binding
FYA48_RS03875	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FYA48_RS03885	COG1034	ATP synthesis coupled electron transport
FYA48_RS03890	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FYA48_RS03895	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FYA48_RS03905	COG0713	ATP synthesis coupled electron transport
FYA48_RS03920	COG1007	ATP synthesis coupled electron transport
FYA48_RS03930	COG0560	Phosphoserine phosphatase
FYA48_RS03935	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FYA48_RS03940	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FYA48_RS03945	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FYA48_RS03960	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FYA48_RS03965	COG0450	alkyl hydroperoxide reductase
FYA48_RS03985	COG1214	PFAM Peptidase M22, glycoprotease
FYA48_RS03990	COG1573	uracil-dna glycosylase
FYA48_RS03995	COG0477	Major facilitator Superfamily
FYA48_RS04000	COG1196	nuclear chromosome segregation
FYA48_RS04010	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FYA48_RS04015	COG1126	abc transporter atp-binding protein
FYA48_RS04020	COG0765	amino acid transport
FYA48_RS04025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYA48_RS04030	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FYA48_RS04035	COG2917	probably involved in intracellular septation
FYA48_RS04040	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FYA48_RS04045	COG1122	ATPase activity
FYA48_RS04050	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FYA48_RS04085	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FYA48_RS04115	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FYA48_RS04120	COG2878	Part of a membrane complex involved in electron transport
FYA48_RS04140	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FYA48_RS04145	COG0251	oxidation-reduction process
FYA48_RS04155	COG3228	Belongs to the MtfA family
FYA48_RS04160	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FYA48_RS04170	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FYA48_RS04180	COG0159	tryptophan synthase activity
FYA48_RS04185	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FYA48_RS04190	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FYA48_RS04205	COG1530	ribonuclease E activity
FYA48_RS04210	COG0564	pseudouridine synthase activity
FYA48_RS04215	COG0546	phosphoglycolate phosphatase activity
FYA48_RS04220	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FYA48_RS04225	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FYA48_RS04230	COG3023	N-Acetylmuramoyl-L-alanine amidase
FYA48_RS04240	COG0424	maF-like protein
FYA48_RS04250	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FYA48_RS04260	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FYA48_RS04270	COG1028	Short-chain dehydrogenase reductase Sdr
FYA48_RS04275	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FYA48_RS04280	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FYA48_RS04305	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FYA48_RS04340	COG0481	GTPase activity
FYA48_RS04345	COG0681	Belongs to the peptidase S26 family
FYA48_RS04350	COG0571	ribonuclease III activity
FYA48_RS04355	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FYA48_RS04360	COG1381	Involved in DNA repair and RecF pathway recombination
FYA48_RS04380	COG0670	Belongs to the BI1 family
FYA48_RS04395	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FYA48_RS04420	COG0583	DNA-binding transcription factor activity
FYA48_RS04435	COG0791	NLP P60 protein
FYA48_RS04440	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FYA48_RS04445	COG3193	protein, possibly involved in utilization of glycolate and propanediol
FYA48_RS04455	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FYA48_RS04475	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FYA48_RS04510	COG1446	asparaginase
FYA48_RS04515	COG4172	Belongs to the ABC transporter superfamily
FYA48_RS04520	COG0747	negative chemotaxis
FYA48_RS04525	COG0601	transmembrane transport
FYA48_RS04550	COG0504	CTP synthase activity
FYA48_RS04560	COG0148	phosphopyruvate hydratase activity
FYA48_RS04575	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FYA48_RS04585	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FYA48_RS04590	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FYA48_RS04630	COG1981	membrane
FYA48_RS04650	COG0039	L-malate dehydrogenase activity
FYA48_RS04655	COG2188	Transcriptional regulator
FYA48_RS04660	COG2009	succinate dehydrogenase
FYA48_RS04665	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FYA48_RS04670	COG1053	succinate dehydrogenase
FYA48_RS04675	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FYA48_RS04680	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FYA48_RS04685	COG0372	Belongs to the citrate synthase family
FYA48_RS04695	COG0583	DNA-binding transcription factor activity
FYA48_RS04700	COG3842	ATPase activity
FYA48_RS04710	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FYA48_RS04715	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FYA48_RS04725	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FYA48_RS04735	COG3128	pkhd-type hydroxylase
FYA48_RS04740	COG4774	siderophore transport
FYA48_RS04750	COG0281	malic enzyme
FYA48_RS04750	COG0280	phosphate acetyltransferase
FYA48_RS04760	COG1297	OPT oligopeptide transporter protein
FYA48_RS04765	COG0567	Dehydrogenase, E1 component
FYA48_RS04770	COG0508	dehydrogenase complex catalyzes the overall conversion of
FYA48_RS04775	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FYA48_RS04780	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FYA48_RS04785	COG1595	DNA-templated transcription, initiation
FYA48_RS04795	COG4774	siderophore transport
FYA48_RS04820	COG2183	response to ionizing radiation
FYA48_RS04825	COG1199	ATP-dependent helicase activity
FYA48_RS04835	COG0564	pseudouridine synthase activity
FYA48_RS04845	COG3243	poly(R)-hydroxyalkanoic acid synthase
FYA48_RS04850	COG1028	Short-chain dehydrogenase reductase Sdr
FYA48_RS04855	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
FYA48_RS04870	COG0672	)-iron permease
FYA48_RS04885	COG2823	Periplasmic or secreted lipoprotein
FYA48_RS04905	COG3237	CsbD-like
FYA48_RS04910	COG3038	cytochrome b561
FYA48_RS04925	COG1132	(ABC) transporter
FYA48_RS04940	COG2833	Protein of unknown function (DUF455)
FYA48_RS04945	COG2951	lytic endotransglycosylase activity
FYA48_RS04970	COG0586	Pfam SNARE associated Golgi protein
FYA48_RS05025	COG0165	Argininosuccinate lyase
FYA48_RS05045	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FYA48_RS05060	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FYA48_RS05065	COG0077	Prephenate dehydratase
FYA48_RS05065	COG1605	Chorismate mutase
FYA48_RS05070	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FYA48_RS05080	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FYA48_RS05085	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FYA48_RS05105	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FYA48_RS05110	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FYA48_RS05115	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FYA48_RS05120	COG0587	DNA-directed DNA polymerase activity
FYA48_RS05130	COG2951	lytic endotransglycosylase activity
FYA48_RS05135	COG0123	including yeast histone deacetylase and acetoin utilization protein
FYA48_RS05150	COG2985	domain, Protein
FYA48_RS05155	COG1960	acyl-CoA dehydrogenase activity
FYA48_RS05160	COG0450	alkyl hydroperoxide reductase
FYA48_RS05165	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FYA48_RS05170	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FYA48_RS05175	COG4208	sulfate ABC transporter
FYA48_RS05180	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FYA48_RS05185	COG0175	sulfate reduction
FYA48_RS05215	COG0335	large ribosomal subunit rRNA binding
FYA48_RS05230	COG3622	Belongs to the hyi family
FYA48_RS05235	COG1162	GTPase activity
FYA48_RS05240	COG0501	Belongs to the peptidase M48B family
FYA48_RS05245	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FYA48_RS05250	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FYA48_RS05255	COG3327	negative regulation of DNA-templated transcription, initiation
FYA48_RS05260	COG3396	Phenylacetate-CoA oxygenase
FYA48_RS05265	COG3460	Phenylacetate-CoA oxygenase
FYA48_RS05270	COG3396	Phenylacetate-CoA oxygenase
FYA48_RS05275	COG2151	metal-sulfur cluster biosynthetic enzyme
FYA48_RS05280	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FYA48_RS05285	COG1012	belongs to the aldehyde dehydrogenase family
FYA48_RS05290	COG1024	Enoyl-CoA hydratase
FYA48_RS05295	COG2050	protein possibly involved in aromatic compounds catabolism
FYA48_RS05325	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FYA48_RS05325	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FYA48_RS05335	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FYA48_RS05340	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FYA48_RS05345	COG2346	COG2346, Truncated hemoglobins
FYA48_RS05350	COG3642	lipopolysaccharide core region biosynthetic process
FYA48_RS05360	COG3842	ATPase activity
FYA48_RS05365	COG1176	ABC-type spermidine putrescine transport system, permease component I
FYA48_RS05370	COG1177	transmembrane transport
FYA48_RS05390	COG1322	Protein conserved in bacteria
FYA48_RS05400	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FYA48_RS05405	COG0704	Plays a role in the regulation of phosphate uptake
FYA48_RS05410	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FYA48_RS05415	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FYA48_RS05415	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FYA48_RS05420	COG1643	Atp-dependent helicase
FYA48_RS05435	COG0438	transferase activity, transferring glycosyl groups
FYA48_RS05440	COG0726	polysaccharide deacetylase
FYA48_RS05445	COG0463	Glycosyl transferase, family 2
FYA48_RS05480	COG1132	(ABC) transporter
FYA48_RS05500	COG0501	Belongs to the peptidase M48B family
FYA48_RS05545	COG1722	exodeoxyribonuclease VII activity
FYA48_RS05550	COG0142	geranyltranstransferase activity
FYA48_RS05555	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FYA48_RS05560	COG1469	GTP cyclohydrolase I activity
FYA48_RS05565	COG0360	Binds together with S18 to 16S ribosomal RNA
FYA48_RS05570	COG2965	DNA replication, synthesis of RNA primer
FYA48_RS05575	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FYA48_RS05580	COG0359	binds to the 23S rRNA
FYA48_RS05590	COG0305	Participates in initiation and elongation during chromosome replication
FYA48_RS05600	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FYA48_RS05605	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FYA48_RS05610	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FYA48_RS05615	COG3737	Protein of unknown function (DUF498/DUF598)
FYA48_RS05620	COG0436	Aminotransferase
FYA48_RS05645	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FYA48_RS05650	COG0308	aminopeptidase N
FYA48_RS05665	COG0312	modulator of DNA gyrase
FYA48_RS05670	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FYA48_RS05690	COG0277	FAD linked oxidase domain protein
FYA48_RS05695	COG0277	FAD linked oxidase domain protein
FYA48_RS05700	COG0247	lactate metabolic process
FYA48_RS05740	COG0583	DNA-binding transcription factor activity
FYA48_RS05745	COG0482	sulfurtransferase activity
FYA48_RS05750	COG0730	response to heat
FYA48_RS05755	COG0625	glutathione transferase activity
FYA48_RS05760	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FYA48_RS05765	COG3909	cytochrome
FYA48_RS05800	COG3706	GGDEF domain
FYA48_RS05815	COG2826	transposase and inactivated derivatives, IS30 family
FYA48_RS05835	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
FYA48_RS05860	COG0069	glutamate synthase activity
FYA48_RS05865	COG2391	methyltransferase activity
FYA48_RS05870	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FYA48_RS05875	COG0679	Auxin Efflux Carrier
FYA48_RS05880	COG2153	protein acetylation
FYA48_RS05900	COG0557	exoribonuclease II activity
FYA48_RS05905	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FYA48_RS05910	COG2873	o-acetylhomoserine
FYA48_RS05915	COG0776	regulation of translation
FYA48_RS05945	COG0642	Histidine kinase
FYA48_RS05950	COG3158	transport of potassium into the cell
FYA48_RS05975	COG0137	argininosuccinate synthase activity
FYA48_RS05980	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FYA48_RS05985	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FYA48_RS05995	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FYA48_RS06010	COG2186	Transcriptional regulator
FYA48_RS06040	COG3836	Belongs to the HpcH HpaI aldolase family
FYA48_RS06045	COG0268	Binds directly to 16S ribosomal RNA
FYA48_RS06090	COG0728	peptidoglycan biosynthetic process
FYA48_RS06100	COG0563	adenylate kinase activity
FYA48_RS06105	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FYA48_RS06110	COG2835	tetraacyldisaccharide 4'-kinase activity
FYA48_RS06115	COG1663	tetraacyldisaccharide 4'-kinase activity
FYA48_RS06120	COG0848	biopolymer transport protein
FYA48_RS06125	COG0811	peptide transport
FYA48_RS06130	COG1570	exodeoxyribonuclease VII activity
FYA48_RS06135	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FYA48_RS06145	COG0038	chloride channel
FYA48_RS06150	COG0183	Belongs to the thiolase family
FYA48_RS06160	COG1278	Cold shock
FYA48_RS06165	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FYA48_RS06175	COG4953	penicillin-binding protein 1C
FYA48_RS06190	COG3008	intermembrane lipid transfer
FYA48_RS06200	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FYA48_RS06200	COG0506	proline dehydrogenase activity
FYA48_RS06200	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FYA48_RS06230	COG0004	ammonium transporteR
FYA48_RS06235	COG0347	Belongs to the P(II) protein family
FYA48_RS06280	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FYA48_RS06285	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FYA48_RS06290	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FYA48_RS06295	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FYA48_RS06295	COG0072	phenylalanine-tRNA ligase activity
FYA48_RS06300	COG0776	regulation of translation
FYA48_RS06330	COG1802	Transcriptional regulator
FYA48_RS06335	COG3181	Tripartite tricarboxylate transporter family receptor
FYA48_RS06355	COG1278	Cold shock
FYA48_RS06365	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FYA48_RS06385	COG1522	sequence-specific DNA binding
FYA48_RS06435	COG5265	(ABC) transporter
FYA48_RS06455	COG0656	L-ascorbic acid biosynthetic process
FYA48_RS06460	COG0667	Aldo Keto reductase
FYA48_RS06475	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FYA48_RS06520	COG1610	YqeY-like protein
FYA48_RS06535	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FYA48_RS06540	COG3246	L-lysine catabolic process to acetate
FYA48_RS06560	COG0318	PFAM AMP-dependent synthetase and ligase
FYA48_RS06575	COG0183	Belongs to the thiolase family
FYA48_RS06580	COG1250	3-hydroxyacyl-CoA dehydrogenase
FYA48_RS06580	COG1024	Enoyl-CoA hydratase
FYA48_RS06590	COG1024	Enoyl-CoA hydratase
FYA48_RS06590	COG1250	3-hydroxyacyl-CoA dehydrogenase
FYA48_RS06595	COG0183	Belongs to the thiolase family
FYA48_RS06600	COG1960	acyl-CoA dehydrogenase activity
FYA48_RS06610	COG1045	serine acetyltransferase
FYA48_RS06620	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FYA48_RS06625	COG0483	inositol monophosphate 1-phosphatase activity
FYA48_RS06630	COG1012	belongs to the aldehyde dehydrogenase family
FYA48_RS06635	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FYA48_RS06650	COG0210	DNA helicase
FYA48_RS06655	COG0598	Magnesium transport protein CorA
FYA48_RS06665	COG0747	negative chemotaxis
FYA48_RS06670	COG0601	transmembrane transport
FYA48_RS06675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FYA48_RS06680	COG4172	Belongs to the ABC transporter superfamily
FYA48_RS06700	COG1346	cytolysis
FYA48_RS06710	COG1028	Short-chain dehydrogenase reductase Sdr
FYA48_RS06715	COG0783	Belongs to the Dps family
FYA48_RS06735	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
FYA48_RS06745	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FYA48_RS06750	COG1845	cytochrome c oxidase, subunit III
FYA48_RS06755	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FYA48_RS06800	COG1666	GTP binding
FYA48_RS06825	COG1028	Short-chain dehydrogenase reductase Sdr
FYA48_RS06830	COG5006	permease, DMT superfamily
FYA48_RS06855	COG2264	protein methyltransferase activity
FYA48_RS06890	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FYA48_RS06895	COG0746	molybdenum cofactor guanylyltransferase activity
FYA48_RS06900	COG0303	'Molybdopterin
FYA48_RS06905	COG0521	Mo-molybdopterin cofactor biosynthetic process
FYA48_RS06910	COG0314	molybdopterin synthase activity
FYA48_RS06920	COG0315	cyclic pyranopterin monophosphate synthase activity
FYA48_RS06925	COG0412	Dienelactone hydrolase
FYA48_RS06935	COG0678	peroxiredoxin activity
FYA48_RS06950	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FYA48_RS06960	COG0542	response to heat
FYA48_RS06975	COG1477	protein flavinylation
FYA48_RS07000	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FYA48_RS07005	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
FYA48_RS07005	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
FYA48_RS07010	COG1562	ergosterol biosynthetic process
FYA48_RS07015	COG1562	ergosterol biosynthetic process
FYA48_RS07020	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FYA48_RS07060	COG0254	rRNA binding
FYA48_RS07065	COG3483	tryptophan 2,3-dioxygenase activity
FYA48_RS07070	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FYA48_RS07075	COG2003	Belongs to the UPF0758 family
FYA48_RS07085	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FYA48_RS07090	COG0625	glutathione transferase activity
FYA48_RS07110	COG0523	cobalamin synthesis protein
FYA48_RS07120	COG0583	DNA-binding transcription factor activity
FYA48_RS07130	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FYA48_RS07135	COG1187	pseudouridine synthase activity
FYA48_RS07140	COG0779	Required for maturation of 30S ribosomal subunits
FYA48_RS07145	COG2251	uridine kinase activity
FYA48_RS07145	COG0195	Participates in both transcription termination and antitermination
FYA48_RS07150	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FYA48_RS07155	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FYA48_RS07160	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FYA48_RS07165	COG1217	gtp-binding protein TYPA
FYA48_RS07180	COG1802	Transcriptional regulator
FYA48_RS07190	COG1024	Enoyl-CoA hydratase
FYA48_RS07195	COG0318	PFAM AMP-dependent synthetase and ligase
FYA48_RS07205	COG2032	superoxide dismutase activity
FYA48_RS07220	COG4120	Belongs to the binding-protein-dependent transport system permease family
FYA48_RS07225	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FYA48_RS07230	COG0725	ABC transporter, periplasmic molybdate-binding protein
FYA48_RS07235	COG4149	molybdate abc transporter
FYA48_RS07265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYA48_RS07270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYA48_RS07275	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FYA48_RS07285	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FYA48_RS07290	COG0736	holo-[acyl-carrier-protein] synthase activity
FYA48_RS07295	COG1472	Belongs to the glycosyl hydrolase 3 family
FYA48_RS07300	COG0322	excinuclease ABC activity
FYA48_RS07305	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FYA48_RS07315	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FYA48_RS07315	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FYA48_RS07320	COG2224	Isocitrate lyase
FYA48_RS07325	COG1846	Transcriptional regulator
FYA48_RS07330	COG1764	response to oxidative stress
FYA48_RS07335	COG1131	(ABC) transporter
FYA48_RS07345	COG0628	permease
FYA48_RS07370	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
FYA48_RS07380	COG2814	Major facilitator Superfamily
FYA48_RS07400	COG3015	lipoprotein NlpE involved in copper resistance
FYA48_RS07410	COG3530	Putative quorum-sensing-regulated virulence factor
FYA48_RS07425	COG0494	nUDIX hydrolase
FYA48_RS07435	COG0697	spore germination
FYA48_RS07440	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FYA48_RS07465	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FYA48_RS07470	COG1702	phosphate starvation-inducible protein PhoH
FYA48_RS07475	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FYA48_RS07480	COG4535	Mg2 and Co2 transporter CorC
FYA48_RS07485	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FYA48_RS07490	COG0667	Aldo Keto reductase
FYA48_RS07510	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FYA48_RS07515	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FYA48_RS07520	COG1862	Preprotein translocase
FYA48_RS07525	COG0343	queuine tRNA-ribosyltransferase activity
FYA48_RS07530	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FYA48_RS07535	COG2027	D-alanyl-D-alanine carboxypeptidase
FYA48_RS07540	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FYA48_RS07550	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FYA48_RS07550	COG1648	precorrin-2 dehydrogenase activity
FYA48_RS07560	COG4575	ribosome binding
FYA48_RS07585	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FYA48_RS07590	COG0741	lytic transglycosylase activity
FYA48_RS07595	COG0436	Aminotransferase
FYA48_RS07605	COG0281	malic enzyme
FYA48_RS07605	COG0280	phosphate acetyltransferase
FYA48_RS07620	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FYA48_RS07625	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FYA48_RS07630	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FYA48_RS07635	COG0126	phosphoglycerate kinase activity
FYA48_RS07650	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FYA48_RS07665	COG0625	glutathione transferase activity
FYA48_RS07685	COG0789	Transcriptional regulator
FYA48_RS07700	COG0306	phosphate transporter
FYA48_RS07705	COG0521	Mo-molybdopterin cofactor biosynthetic process
FYA48_RS07715	COG0739	heme binding
FYA48_RS07725	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FYA48_RS07765	COG0456	acetyltransferase
FYA48_RS07770	COG1301	dicarboxylic acid transport
FYA48_RS07780	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FYA48_RS07785	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FYA48_RS07790	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FYA48_RS07795	COG0009	L-threonylcarbamoyladenylate synthase
FYA48_RS07805	COG4771	TonB-dependent receptor
FYA48_RS07835	COG1960	acyl-CoA dehydrogenase activity
FYA48_RS07840	COG0028	Belongs to the TPP enzyme family
FYA48_RS07845	COG0583	DNA-binding transcription factor activity
FYA48_RS07850	COG4974	Belongs to the 'phage' integrase family
FYA48_RS07855	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FYA48_RS07860	COG1686	Belongs to the peptidase S11 family
FYA48_RS07890	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FYA48_RS07895	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FYA48_RS07900	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FYA48_RS07920	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FYA48_RS07925	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FYA48_RS07930	COG0505	Belongs to the CarA family
FYA48_RS07935	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FYA48_RS07945	COG1028	Short-chain dehydrogenase reductase Sdr
FYA48_RS07950	COG0406	alpha-ribazole phosphatase activity
FYA48_RS07980	COG2233	PERMEase
FYA48_RS07985	COG3620	sequence-specific DNA binding
FYA48_RS07995	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FYA48_RS08005	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FYA48_RS08010	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FYA48_RS08020	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FYA48_RS08035	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FYA48_RS08055	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FYA48_RS08115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FYA48_RS08145	COG0540	Belongs to the ATCase OTCase family
FYA48_RS08150	COG2974	May be involved in recombination
FYA48_RS08175	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FYA48_RS08180	COG2137	regulation of response to DNA damage stimulus
FYA48_RS08190	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FYA48_RS08210	COG0045	succinate-CoA ligase (ADP-forming) activity
FYA48_RS08215	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FYA48_RS08220	COG0861	Integral membrane protein TerC family
FYA48_RS08225	COG0861	Integral membrane protein TerC family
FYA48_RS08230	COG0181	hydroxymethylbilane synthase activity
FYA48_RS08270	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FYA48_RS08315	COG1450	Type ii and iii secretion system protein
FYA48_RS08365	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FYA48_RS08375	COG1295	ribonuclease BN
FYA48_RS08385	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FYA48_RS08405	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FYA48_RS08410	COG0501	Belongs to the peptidase M48B family
FYA48_RS08415	COG2197	response regulator
FYA48_RS08440	COG0066	3-isopropylmalate dehydratase activity
FYA48_RS08450	COG0473	3-isopropylmalate dehydrogenase activity
FYA48_RS08455	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FYA48_RS08465	COG0101	tRNA pseudouridine synthase activity
FYA48_RS08470	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FYA48_RS08475	COG0135	phosphoribosylanthranilate isomerase activity
FYA48_RS08495	COG2801	Transposase and inactivated derivatives
FYA48_RS08500	COG2801	Transposase and inactivated derivatives
FYA48_RS08540	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FYA48_RS08545	COG2197	response regulator
FYA48_RS08550	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FYA48_RS08555	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FYA48_RS08570	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FYA48_RS08575	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FYA48_RS08585	COG1764	response to oxidative stress
FYA48_RS08600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYA48_RS08605	COG0765	amino acid transport
FYA48_RS08610	COG0765	amino acid transport
FYA48_RS08620	COG0756	dUTP diphosphatase activity
FYA48_RS08650	COG1522	sequence-specific DNA binding
FYA48_RS08670	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FYA48_RS08675	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FYA48_RS08680	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FYA48_RS08685	COG0196	riboflavin kinase activity
FYA48_RS08695	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FYA48_RS08695	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FYA48_RS08725	COG0210	DNA helicase
FYA48_RS08730	COG4771	TonB-dependent receptor
FYA48_RS08735	COG0488	(ABC) transporter
FYA48_RS08740	COG2890	protein-(glutamine-N5) methyltransferase activity
FYA48_RS08745	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FYA48_RS08750	COG2171	N-acyltransferase activity
FYA48_RS08805	COG2801	Transposase and inactivated derivatives
FYA48_RS08845	COG2814	Major facilitator Superfamily
FYA48_RS08870	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FYA48_RS08875	COG2900	Belongs to the SlyX family
FYA48_RS08890	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FYA48_RS08910	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FYA48_RS08935	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FYA48_RS08940	COG0583	DNA-binding transcription factor activity
FYA48_RS08945	COG1028	Short-chain dehydrogenase reductase Sdr
FYA48_RS08955	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FYA48_RS08960	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FYA48_RS08975	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FYA48_RS08980	COG0508	dehydrogenase complex catalyzes the overall conversion of
FYA48_RS08985	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FYA48_RS09000	COG4566	intracellular signal transduction
FYA48_RS09005	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FYA48_RS09025	COG1999	signal sequence binding
FYA48_RS09045	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYA48_RS09050	COG0583	DNA-binding transcription factor activity
FYA48_RS09055	COG1187	pseudouridine synthase activity
FYA48_RS09060	COG3161	chorismate lyase activity
FYA48_RS09075	COG1280	lysine exporter protein (LysE YggA)
FYA48_RS09115	COG1129	ABC transporter
FYA48_RS09130	COG0583	DNA-binding transcription factor activity
FYA48_RS09160	COG1185	polyribonucleotide nucleotidyltransferase activity
FYA48_RS09165	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FYA48_RS09180	COG1183	phosphatidylcholine synthase activity
FYA48_RS09190	COG0440	acetolactate synthase activity
FYA48_RS09195	COG0028	Belongs to the TPP enzyme family
FYA48_RS09220	COG3022	response to hydroperoxide
FYA48_RS09230	COG1028	Short-chain dehydrogenase reductase Sdr
FYA48_RS09245	COG3486	L-lysine 6-monooxygenase (NADPH) activity
FYA48_RS09275	COG2814	Major facilitator Superfamily
FYA48_RS09305	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FYA48_RS09340	COG2733	membrane
FYA48_RS09365	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FYA48_RS09385	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYA48_RS09390	COG1129	ABC transporter
FYA48_RS09390	COG0842	Transport permease protein
FYA48_RS09395	COG0842	Transport permease protein
FYA48_RS09405	COG1028	Short-chain dehydrogenase reductase Sdr
FYA48_RS09415	COG2259	Doxx family
FYA48_RS09445	COG0415	Belongs to the DNA photolyase family
FYA48_RS09465	COG0386	Belongs to the glutathione peroxidase family
FYA48_RS09480	COG0095	Lipoate-protein ligase
FYA48_RS09490	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FYA48_RS09500	COG0010	Belongs to the arginase family
FYA48_RS09510	COG0765	amino acid transport
FYA48_RS09515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYA48_RS09530	COG0084	hydrolase, TatD family'
FYA48_RS09540	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FYA48_RS09545	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FYA48_RS09555	COG2175	clavaminate synthase activity
FYA48_RS09560	COG0583	DNA-binding transcription factor activity
FYA48_RS09585	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FYA48_RS09595	COG2914	Belongs to the UPF0125 (RnfH) family
FYA48_RS09605	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FYA48_RS09635	COG0519	Catalyzes the synthesis of GMP from XMP
FYA48_RS09635	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FYA48_RS09645	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FYA48_RS09655	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FYA48_RS09660	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FYA48_RS09665	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FYA48_RS09675	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FYA48_RS09680	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FYA48_RS09690	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FYA48_RS09695	COG0750	zinc metalloprotease
FYA48_RS09700	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FYA48_RS09710	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FYA48_RS09715	COG0233	cytoplasmic translational termination
FYA48_RS09720	COG0528	UMP kinase activity
FYA48_RS09725	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FYA48_RS09730	COG0052	Belongs to the universal ribosomal protein uS2 family
FYA48_RS09735	COG0024	Methionine aminopeptidase
FYA48_RS09740	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FYA48_RS09760	COG1286	toxin biosynthetic process
FYA48_RS09770	COG0285	dihydrofolate synthase activity
FYA48_RS09780	COG3181	Tripartite tricarboxylate transporter family receptor
FYA48_RS09785	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYA48_RS09825	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FYA48_RS09835	COG1677	Flagellar hook-basal body complex protein FliE
FYA48_RS09845	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FYA48_RS09850	COG1317	bacterial-type flagellum organization
FYA48_RS09870	COG1580	Controls the rotational direction of flagella during chemotaxis
FYA48_RS09880	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FYA48_RS09905	COG0840	transmembrane signaling receptor activity
FYA48_RS09910	COG0840	transmembrane signaling receptor activity
FYA48_RS09930	COG1191	sigma factor activity
FYA48_RS09965	COG2199	diguanylate cyclase activity
FYA48_RS09965	COG2203	Gaf domain
FYA48_RS09975	COG1619	proteins homologs of microcin C7 resistance protein MccF
FYA48_RS10000	COG1126	abc transporter atp-binding protein
FYA48_RS10005	COG0765	amino acid transport
FYA48_RS10010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYA48_RS10055	COG2200	EAL domain
FYA48_RS10075	COG1253	flavin adenine dinucleotide binding
FYA48_RS10080	COG4251	negative regulation of phosphorylation
FYA48_RS10080	COG2203	Gaf domain
FYA48_RS10080	COG3706	GGDEF domain
FYA48_RS10080	COG5001	Diguanylate cyclase
FYA48_RS10085	COG2197	response regulator
FYA48_RS10090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYA48_RS10090	COG2205	protein histidine kinase activity
FYA48_RS10115	COG0076	glutamate decarboxylase activity
FYA48_RS10120	COG2985	domain, Protein
FYA48_RS10125	COG3189	MarR family transcriptional regulator
FYA48_RS10135	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FYA48_RS10145	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FYA48_RS10145	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FYA48_RS10155	COG0028	Belongs to the TPP enzyme family
FYA48_RS10165	COG1012	belongs to the aldehyde dehydrogenase family
FYA48_RS10175	COG0688	phosphatidylethanolamine metabolic process
FYA48_RS10180	COG1304	FMN binding
FYA48_RS10185	COG1464	Belongs to the NlpA lipoprotein family
FYA48_RS10205	COG0697	spore germination
FYA48_RS10210	COG2133	pyrroloquinoline quinone binding
FYA48_RS10215	COG0625	glutathione transferase activity
FYA48_RS10225	COG1794	racemase activity, acting on amino acids and derivatives
FYA48_RS10245	COG0559	Belongs to the binding-protein-dependent transport system permease family
FYA48_RS10255	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FYA48_RS10270	COG1175	transmembrane transport
FYA48_RS10275	COG0395	ABC-type sugar transport system, permease component
FYA48_RS10280	COG3842	ATPase activity
FYA48_RS10305	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FYA48_RS10320	COG0438	transferase activity, transferring glycosyl groups
FYA48_RS10345	COG0463	Glycosyl transferase, family 2
FYA48_RS10360	COG0783	Belongs to the Dps family
FYA48_RS10365	COG0583	DNA-binding transcription factor activity
FYA48_RS10370	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FYA48_RS10400	COG1840	ABC-type Fe3 transport system, periplasmic component
FYA48_RS10410	COG3842	ATPase activity
FYA48_RS10415	COG1741	Belongs to the pirin family
FYA48_RS10420	COG1741	Belongs to the pirin family
FYA48_RS10425	COG0583	DNA-binding transcription factor activity
FYA48_RS10440	COG0174	glutamine synthetase
FYA48_RS10445	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FYA48_RS10450	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FYA48_RS10460	COG0840	transmembrane signaling receptor activity
FYA48_RS10470	COG0583	DNA-binding transcription factor activity
FYA48_RS10475	COG1960	acyl-CoA dehydrogenase activity
FYA48_RS10480	COG2079	MmgE PrpD family protein
FYA48_RS10490	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FYA48_RS10495	COG1561	YicC-like family, N-terminal region
FYA48_RS10505	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FYA48_RS10510	COG0791	NLP P60 protein
FYA48_RS10515	COG1028	Short-chain dehydrogenase reductase Sdr
FYA48_RS10520	COG0194	GDP metabolic process
FYA48_RS10525	COG1758	RNA polymerase activity
FYA48_RS10530	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FYA48_RS10535	COG1126	abc transporter atp-binding protein
FYA48_RS10540	COG0765	amino acid transport
FYA48_RS10545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYA48_RS10555	COG2831	hemolysin activation secretion protein
FYA48_RS10565	COG3188	usher protein
FYA48_RS10570	COG3121	Chaperone
FYA48_RS10585	COG3210	domain, Protein
FYA48_RS10585	COG3064	Membrane
FYA48_RS10585	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
FYA48_RS10595	COG4181	ATPase activity
FYA48_RS10605	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FYA48_RS10610	COG0584	glycerophosphoryl diester phosphodiesterase
FYA48_RS10615	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FYA48_RS10625	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FYA48_RS10625	COG0678	peroxiredoxin activity
FYA48_RS10635	COG2217	Heavy metal translocating P-type atpase
FYA48_RS10640	COG0789	Transcriptional regulator
FYA48_RS10645	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FYA48_RS10680	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FYA48_RS10690	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FYA48_RS10715	COG0583	DNA-binding transcription factor activity
FYA48_RS10720	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FYA48_RS10725	COG2252	PERMEase
FYA48_RS10730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FYA48_RS10735	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FYA48_RS10770	COG0488	(ABC) transporter
FYA48_RS10775	COG1619	proteins homologs of microcin C7 resistance protein MccF
FYA48_RS10780	COG0590	tRNA wobble adenosine to inosine editing
FYA48_RS10795	COG1320	monovalent cation:proton antiporter activity
FYA48_RS10800	COG2212	antiporter activity
FYA48_RS10805	COG1863	multisubunit Na H antiporter MnhE subunit
FYA48_RS10810	COG0651	ATP synthesis coupled electron transport
FYA48_RS10815	COG1006	Multisubunit Na H antiporter MnhC subunit
FYA48_RS10820	COG2111	Na H antiporter
FYA48_RS10820	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FYA48_RS10825	COG3181	Tripartite tricarboxylate transporter family receptor
FYA48_RS10850	COG0420	3'-5' exonuclease activity
FYA48_RS10885	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FYA48_RS10895	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FYA48_RS10905	COG2130	NADP-dependent
FYA48_RS10910	COG1309	transcriptional regulator
FYA48_RS10920	COG1131	(ABC) transporter
FYA48_RS10925	COG0842	Transport permease protein
FYA48_RS10935	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FYA48_RS10970	COG0602	queuosine metabolic process
FYA48_RS10975	COG0720	synthase
FYA48_RS11010	COG0587	DNA-directed DNA polymerase activity
FYA48_RS11020	COG0390	transport system, permease component
FYA48_RS11025	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FYA48_RS11030	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
FYA48_RS11085	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FYA48_RS11110	COG5507	3-demethylubiquinone-9 3-methyltransferase
FYA48_RS11145	COG1396	sequence-specific DNA binding
FYA48_RS11170	COG0583	DNA-binding transcription factor activity
FYA48_RS11175	COG2814	Major facilitator Superfamily
FYA48_RS11200	COG2807	transmembrane transport
FYA48_RS11205	COG2207	Transcriptional regulator
FYA48_RS11210	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FYA48_RS11215	COG2814	Major facilitator Superfamily
FYA48_RS11230	COG1012	belongs to the aldehyde dehydrogenase family
FYA48_RS11265	COG0583	DNA-binding transcription factor activity
FYA48_RS11290	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FYA48_RS11315	COG0384	phenazine biosynthesis protein PhzF
FYA48_RS11320	COG1733	regulation of RNA biosynthetic process
FYA48_RS11355	COG3177	Filamentation induced by cAMP protein fic
FYA48_RS11365	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FYA48_RS11365	COG0519	Catalyzes the synthesis of GMP from XMP
FYA48_RS11380	COG1695	Transcriptional regulator
FYA48_RS11395	COG2072	flavoprotein involved in K transport
FYA48_RS11400	COG0601	transmembrane transport
FYA48_RS11420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FYA48_RS11430	COG4608	Belongs to the ABC transporter superfamily
FYA48_RS11435	COG0747	negative chemotaxis
FYA48_RS11475	COG0047	phosphoribosylformylglycinamidine synthase activity
FYA48_RS11475	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FYA48_RS11480	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FYA48_RS11500	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FYA48_RS11500	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FYA48_RS11505	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FYA48_RS11515	COG0613	PHP domain protein
FYA48_RS11575	COG1012	belongs to the aldehyde dehydrogenase family
FYA48_RS11585	COG0583	DNA-binding transcription factor activity
FYA48_RS11605	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FYA48_RS11615	COG3181	Tripartite tricarboxylate transporter family receptor
FYA48_RS11625	COG3181	Tripartite tricarboxylate transporter family receptor
FYA48_RS11655	COG1595	DNA-templated transcription, initiation
FYA48_RS11660	COG3712	iron ion homeostasis
FYA48_RS11670	COG0084	hydrolase, TatD family'
FYA48_RS11675	COG1136	(ABC) transporter
FYA48_RS11690	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FYA48_RS11700	COG1028	Short-chain dehydrogenase reductase Sdr
FYA48_RS11705	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FYA48_RS11715	COG1803	Methylglyoxal synthase
FYA48_RS11735	COG2801	Transposase and inactivated derivatives
FYA48_RS11740	COG2801	Transposase and inactivated derivatives
FYA48_RS11765	COG2975	iron-sulfur cluster assembly
FYA48_RS11770	COG0633	Ferredoxin
FYA48_RS11775	COG0443	Heat shock 70 kDa protein
FYA48_RS11780	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FYA48_RS11785	COG0316	Belongs to the HesB IscA family
FYA48_RS11790	COG0822	iron-sulfur transferase activity
FYA48_RS11795	COG1104	cysteine desulfurase activity
FYA48_RS11805	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FYA48_RS11810	COG0556	nucleotide-excision repair
FYA48_RS11825	COG0583	DNA-binding transcription factor activity
FYA48_RS11845	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FYA48_RS11885	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FYA48_RS11900	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FYA48_RS11910	COG0740	serine-type endopeptidase activity
FYA48_RS11915	COG0544	peptidyl-prolyl cis-trans isomerase activity
FYA48_RS11960	COG2801	Transposase and inactivated derivatives
FYA48_RS11970	COG1278	Cold shock
FYA48_RS12000	COG2433	Pfam Transposase IS66
FYA48_RS12060	COG1530	ribonuclease E activity
FYA48_RS12095	COG1846	Transcriptional regulator
FYA48_RS12105	COG1566	PFAM secretion protein HlyD family protein
FYA48_RS12110	COG2814	Major facilitator Superfamily
FYA48_RS12135	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FYA48_RS12150	COG0433	COG0433 Predicted ATPase
FYA48_RS12155	COG0217	transcriptional regulatory protein
FYA48_RS12160	COG0151	Belongs to the GarS family
FYA48_RS12170	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FYA48_RS12175	COG0799	negative regulation of ribosome biogenesis
FYA48_RS12180	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FYA48_RS12185	COG0424	maF-like protein
FYA48_RS12195	COG4191	Histidine kinase
FYA48_RS12200	COG2204	response regulator
FYA48_RS12225	COG0500	methyltransferase
FYA48_RS12240	COG0803	Belongs to the bacterial solute-binding protein 9 family
FYA48_RS12245	COG1121	(ABC) transporter
FYA48_RS12250	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FYA48_RS12255	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FYA48_RS12270	COG4993	Dehydrogenase
FYA48_RS12280	COG4772	TonB-dependent receptor
FYA48_RS12285	COG2814	Major facilitator Superfamily
FYA48_RS12305	COG0037	tRNA processing
FYA48_RS12310	COG0825	malonyl-CoA metabolic process
FYA48_RS12320	COG0215	cysteine-tRNA ligase activity
FYA48_RS12330	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FYA48_RS12335	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FYA48_RS12340	COG1968	undecaprenyl-diphosphatase activity
FYA48_RS12345	COG1253	flavin adenine dinucleotide binding
FYA48_RS12350	COG0483	inositol monophosphate 1-phosphatase activity
FYA48_RS12370	COG0668	transmembrane transport
FYA48_RS12395	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FYA48_RS12405	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FYA48_RS12420	COG1802	Transcriptional regulator
FYA48_RS12440	COG3360	Dodecin
FYA48_RS12460	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FYA48_RS12465	COG2850	peptidyl-arginine hydroxylation
FYA48_RS12475	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
FYA48_RS12480	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FYA48_RS12485	COG1994	Peptidase M50
FYA48_RS12490	COG0009	L-threonylcarbamoyladenylate synthase
FYA48_RS12495	COG2321	neutral zinc metallopeptidase
FYA48_RS12515	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FYA48_RS12525	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FYA48_RS12535	COG2271	Major facilitator Superfamily
FYA48_RS12610	COG2200	EAL domain
FYA48_RS12610	COG2202	Pas domain
FYA48_RS12610	COG2199	diguanylate cyclase activity
FYA48_RS12615	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
FYA48_RS12635	COG1960	acyl-CoA dehydrogenase activity
FYA48_RS12640	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYA48_RS12645	COG2186	Transcriptional regulator
FYA48_RS12670	COG1595	DNA-templated transcription, initiation
FYA48_RS12705	COG1028	Short-chain dehydrogenase reductase Sdr
FYA48_RS12720	COG0179	Fumarylacetoacetate (FAA) hydrolase
FYA48_RS12740	COG4604	ABC transporter, ATP-binding protein
FYA48_RS12745	COG4605	iron ion homeostasis
FYA48_RS12750	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FYA48_RS12755	COG4607	ABC-type enterochelin transport system periplasmic component
FYA48_RS12760	COG0438	transferase activity, transferring glycosyl groups
FYA48_RS12770	COG0149	triose-phosphate isomerase activity
FYA48_RS12775	COG3321	synthase
FYA48_RS12775	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FYA48_RS12775	COG4221	oxidoreductase activity
FYA48_RS12775	COG0604	alcohol dehydrogenase
FYA48_RS12805	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FYA48_RS12805	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FYA48_RS12810	COG0668	transmembrane transport
FYA48_RS12815	COG0165	Argininosuccinate lyase
FYA48_RS12825	COG0789	Transcriptional regulator
FYA48_RS12835	COG0501	Belongs to the peptidase M48B family
FYA48_RS12840	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FYA48_RS12865	COG1024	Enoyl-CoA hydratase
FYA48_RS12870	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYA48_RS12890	COG3468	outer membrane autotransporter barrel domain protein
FYA48_RS12935	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FYA48_RS12940	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FYA48_RS12945	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FYA48_RS12950	COG1674	ftsk spoiiie
FYA48_RS12955	COG0492	ferredoxin-NADP+ reductase activity
FYA48_RS12960	COG1193	negative regulation of DNA recombination
FYA48_RS12975	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FYA48_RS12990	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FYA48_RS12995	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FYA48_RS13000	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FYA48_RS13010	COG0745	RESPONSE REGULATOR receiver
FYA48_RS13045	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FYA48_RS13065	COG0612	Peptidase, M16
FYA48_RS13075	COG0443	Heat shock 70 kDa protein
FYA48_RS13085	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FYA48_RS13095	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FYA48_RS13100	COG1420	regulation of RNA biosynthetic process
FYA48_RS13105	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FYA48_RS13110	COG0497	DNA recombination
FYA48_RS13140	COG0735	belongs to the Fur family
FYA48_RS13145	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FYA48_RS13190	COG2828	Protein conserved in bacteria
FYA48_RS13195	COG1280	lysine exporter protein (LysE YggA)
FYA48_RS13200	COG3181	Tripartite tricarboxylate transporter family receptor
FYA48_RS13215	COG1028	Short-chain dehydrogenase reductase Sdr
FYA48_RS13220	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FYA48_RS13225	COG1802	Transcriptional regulator
FYA48_RS13230	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FYA48_RS13235	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FYA48_RS13240	COG1335	isochorismatase
FYA48_RS13245	COG0523	cobalamin synthesis protein
FYA48_RS13275	COG0583	DNA-binding transcription factor activity
FYA48_RS13285	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FYA48_RS13290	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FYA48_RS13295	COG0167	dihydroorotate dehydrogenase activity
FYA48_RS13340	COG1414	Transcriptional regulator
FYA48_RS13360	COG0513	Belongs to the DEAD box helicase family
FYA48_RS13385	COG0429	hydrolase of the alpha beta-hydrolase fold
FYA48_RS13430	COG0006	proline dipeptidase activity
FYA48_RS13440	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FYA48_RS13470	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FYA48_RS13475	COG0632	four-way junction helicase activity
FYA48_RS13490	COG2255	four-way junction helicase activity
FYA48_RS13495	COG0514	ATP-dependent DNA helicase (RecQ)
FYA48_RS13515	COG1294	oxidase, subunit
FYA48_RS13525	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FYA48_RS13530	COG0850	regulation of cytokinetic process
FYA48_RS13535	COG2894	cell division
FYA48_RS13540	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FYA48_RS13565	COG0488	(ABC) transporter
FYA48_RS13580	COG4608	Belongs to the ABC transporter superfamily
FYA48_RS13585	COG0444	Belongs to the ABC transporter superfamily
FYA48_RS13590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FYA48_RS13605	COG1215	transferase activity, transferring glycosyl groups
FYA48_RS13610	COG0583	DNA-binding transcription factor activity
FYA48_RS13615	COG1368	sulfuric ester hydrolase activity
FYA48_RS13620	COG1686	Belongs to the peptidase S11 family
FYA48_RS13630	COG1280	lysine exporter protein (LysE YggA)
FYA48_RS13640	COG1064	alcohol dehydrogenase
FYA48_RS13645	COG4191	Histidine kinase
FYA48_RS13650	COG4566	intracellular signal transduction
FYA48_RS13660	COG1802	Transcriptional regulator
FYA48_RS13685	COG3181	Tripartite tricarboxylate transporter family receptor
FYA48_RS13690	COG0513	Belongs to the DEAD box helicase family
FYA48_RS13695	COG0668	transmembrane transport
FYA48_RS13710	COG1595	DNA-templated transcription, initiation
FYA48_RS13750	COG0583	DNA-binding transcription factor activity
FYA48_RS13755	COG0531	amino acid
FYA48_RS13760	COG1982	Orn Lys Arg decarboxylase major
FYA48_RS13785	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FYA48_RS13790	COG0459	protein refolding
FYA48_RS13800	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FYA48_RS13805	COG1252	NADH dehydrogenase
FYA48_RS13810	COG0284	orotidine-5'-phosphate decarboxylase activity
FYA48_RS13820	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FYA48_RS13830	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FYA48_RS13835	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FYA48_RS13865	COG1595	DNA-templated transcription, initiation
FYA48_RS13875	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FYA48_RS13880	COG3639	organic phosphonate transmembrane transporter activity
FYA48_RS13885	COG3639	organic phosphonate transmembrane transporter activity
FYA48_RS13900	COG0742	ribosomal rna small subunit methyltransferase
FYA48_RS13905	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FYA48_RS13910	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FYA48_RS13915	COG3135	benzoate transporter
FYA48_RS13935	COG4774	siderophore transport
FYA48_RS13960	COG1024	Enoyl-CoA hydratase
FYA48_RS13965	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FYA48_RS13970	COG1960	acyl-CoA dehydrogenase activity
FYA48_RS13980	COG0318	PFAM AMP-dependent synthetase and ligase
FYA48_RS13985	COG3181	Tripartite tricarboxylate transporter family receptor
FYA48_RS13995	COG0583	DNA-binding transcription factor activity
FYA48_RS14020	COG0277	FAD linked oxidase domain protein
FYA48_RS14040	COG1802	Transcriptional regulator
FYA48_RS14055	COG2271	Major facilitator Superfamily
FYA48_RS14065	COG0583	DNA-binding transcription factor activity
FYA48_RS14090	COG0012	GTP binding
FYA48_RS14100	COG0193	aminoacyl-tRNA hydrolase activity
FYA48_RS14105	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FYA48_RS14110	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FYA48_RS14120	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FYA48_RS14135	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FYA48_RS14160	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FYA48_RS14170	COG1368	sulfuric ester hydrolase activity
FYA48_RS14175	COG2186	Transcriptional regulator
FYA48_RS14185	COG3181	Tripartite tricarboxylate transporter family receptor
FYA48_RS14200	COG0277	FAD linked oxidase domain protein
FYA48_RS14215	COG0166	Belongs to the GPI family
FYA48_RS14220	COG0438	transferase activity, transferring glycosyl groups
FYA48_RS14225	COG0438	transferase activity, transferring glycosyl groups
FYA48_RS14240	COG0438	transferase activity, transferring glycosyl groups
FYA48_RS14255	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FYA48_RS14260	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FYA48_RS14275	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
FYA48_RS14285	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FYA48_RS14295	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FYA48_RS14300	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FYA48_RS14315	COG0747	negative chemotaxis
FYA48_RS14325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FYA48_RS14330	COG4172	Belongs to the ABC transporter superfamily
FYA48_RS14355	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FYA48_RS14355	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FYA48_RS14360	COG0509	glycine decarboxylation via glycine cleavage system
FYA48_RS14365	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FYA48_RS14370	COG2081	HI0933 family
FYA48_RS14385	COG0456	acetyltransferase
FYA48_RS14390	COG0717	Belongs to the dCTP deaminase family
FYA48_RS14405	COG0489	protein tyrosine kinase activity
FYA48_RS14415	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FYA48_RS14415	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FYA48_RS14440	COG3539	Fimbrial protein
FYA48_RS14455	COG0745	RESPONSE REGULATOR receiver
FYA48_RS14485	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
FYA48_RS14500	COG2084	Dehydrogenase
FYA48_RS14505	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FYA48_RS14530	COG3842	ATPase activity
FYA48_RS14535	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FYA48_RS14540	COG1960	acyl-CoA dehydrogenase activity
FYA48_RS14550	COG0583	DNA-binding transcription factor activity
FYA48_RS14560	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYA48_RS14565	COG1024	Enoyl-CoA hydratase
FYA48_RS14585	COG0583	DNA-binding transcription factor activity
FYA48_RS14590	COG1408	metallophosphoesterase
FYA48_RS14595	COG0625	glutathione transferase activity
FYA48_RS14630	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FYA48_RS14630	COG0426	domain, Protein
FYA48_RS14635	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FYA48_RS14640	COG0583	DNA-binding transcription factor activity
FYA48_RS14650	COG1024	Enoyl-CoA hydratase
FYA48_RS14660	COG1960	acyl-CoA dehydrogenase activity
FYA48_RS14665	COG1028	Short-chain dehydrogenase reductase Sdr
FYA48_RS14670	COG1028	Short-chain dehydrogenase reductase Sdr
FYA48_RS14690	COG3181	Tripartite tricarboxylate transporter family receptor
FYA48_RS14695	COG1028	Short-chain dehydrogenase reductase Sdr
FYA48_RS14705	COG3181	Tripartite tricarboxylate transporter family receptor
FYA48_RS14745	COG0583	DNA-binding transcription factor activity
FYA48_RS14750	COG1960	acyl-CoA dehydrogenase activity
FYA48_RS14755	COG3181	Tripartite tricarboxylate transporter family receptor
FYA48_RS14760	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYA48_RS14765	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FYA48_RS14790	COG0560	Phosphoserine phosphatase
FYA48_RS14795	COG0583	DNA-binding transcription factor activity
FYA48_RS14805	COG3842	ATPase activity
FYA48_RS14820	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FYA48_RS14840	COG0625	glutathione transferase activity
FYA48_RS14880	COG4336	lyase activity
FYA48_RS14890	COG0326	Molecular chaperone. Has ATPase activity
FYA48_RS14895	COG2233	PERMEase
FYA48_RS14935	COG2818	Glycosylase
FYA48_RS14940	COG0727	PFAM Uncharacterised protein family (UPF0153)
FYA48_RS14965	COG0402	S-adenosylhomocysteine deaminase activity
FYA48_RS14980	COG0156	8-amino-7-oxononanoate synthase activity
FYA48_RS14985	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FYA48_RS15035	COG1464	Belongs to the NlpA lipoprotein family
FYA48_RS15040	COG2011	ABC-type metal ion transport system permease component
FYA48_RS15045	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FYA48_RS15050	COG1501	Belongs to the glycosyl hydrolase 31 family
FYA48_RS15055	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FYA48_RS15055	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FYA48_RS15060	COG0483	inositol monophosphate 1-phosphatase activity
FYA48_RS15065	COG0318	PFAM AMP-dependent synthetase and ligase
FYA48_RS15070	COG1473	amidohydrolase
FYA48_RS15075	COG0583	DNA-binding transcription factor activity
FYA48_RS15080	COG2855	membrane
FYA48_RS15090	COG2239	Acts as a magnesium transporter
FYA48_RS15105	COG1522	sequence-specific DNA binding
FYA48_RS15140	COG0330	HflC and HflK could
FYA48_RS15145	COG0330	HflC and HflK could
FYA48_RS15150	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FYA48_RS15155	COG1923	regulation of RNA biosynthetic process
FYA48_RS15165	COG1160	GTP binding
FYA48_RS15170	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FYA48_RS15175	COG2976	Protein conserved in bacteria
FYA48_RS15180	COG0124	histidyl-tRNA synthetase
FYA48_RS15195	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FYA48_RS15200	COG0105	UTP biosynthetic process
FYA48_RS15205	COG0525	valine-tRNA ligase activity
FYA48_RS15215	COG0336	Belongs to the RNA methyltransferase TrmD family
FYA48_RS15220	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FYA48_RS15225	COG0228	four-way junction DNA binding
FYA48_RS15230	COG0425	Belongs to the sulfur carrier protein TusA family
FYA48_RS15235	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FYA48_RS15300	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FYA48_RS15305	COG0543	2 iron, 2 sulfur cluster binding
FYA48_RS15305	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FYA48_RS15310	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FYA48_RS15315	COG2076	Multidrug Resistance protein
FYA48_RS15320	COG0633	Ferredoxin
FYA48_RS15320	COG3217	Mosc domain protein beta barrel domain protein
FYA48_RS15325	COG5285	phytanoyl-CoA dioxygenase
FYA48_RS15330	COG0662	Cupin 2, conserved barrel domain protein
FYA48_RS15340	COG0456	acetyltransferase
FYA48_RS15355	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FYA48_RS15385	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FYA48_RS15395	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FYA48_RS15400	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FYA48_RS15405	COG1760	l-serine dehydratase
FYA48_RS15410	COG1283	sodium-dependent phosphate transmembrane transporter activity
FYA48_RS15415	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FYA48_RS15420	COG0412	Dienelactone hydrolase
FYA48_RS15425	COG0428	transporter
FYA48_RS15435	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FYA48_RS15445	COG1845	cytochrome c oxidase, subunit III
FYA48_RS15450	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FYA48_RS15460	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FYA48_RS15460	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FYA48_RS15485	COG1942	4-Oxalocrotonate Tautomerase
FYA48_RS15495	COG4176	ABC-type proline glycine betaine transport system permease component
FYA48_RS15515	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FYA48_RS15520	COG2814	Major facilitator Superfamily
FYA48_RS15525	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FYA48_RS15530	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FYA48_RS15555	COG1846	Transcriptional regulator
FYA48_RS15560	COG2814	Major facilitator Superfamily
FYA48_RS15565	COG0495	leucyl-tRNA aminoacylation
FYA48_RS15580	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FYA48_RS15600	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYA48_RS15605	COG2274	protein secretion by the type I secretion system
FYA48_RS15650	COG0427	acetyl-CoA hydrolase
FYA48_RS15660	COG3264	Mechanosensitive ion channel
FYA48_RS15660	COG1511	domain protein
FYA48_RS15665	COG0730	response to heat
FYA48_RS15680	COG2176	DNA-directed DNA polymerase activity
FYA48_RS15700	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FYA48_RS15705	COG3384	dioxygenase
FYA48_RS15720	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FYA48_RS15790	COG4964	Belongs to the GSP D family
FYA48_RS15835	COG1846	Transcriptional regulator
FYA48_RS15870	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FYA48_RS15880	COG2070	2-Nitropropane dioxygenase
FYA48_RS15885	COG2070	2-Nitropropane dioxygenase
FYA48_RS15895	COG2610	gluconate transmembrane transporter activity
FYA48_RS15910	COG1408	metallophosphoesterase
FYA48_RS15915	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FYA48_RS15915	COG0493	'glutamate synthase
FYA48_RS15920	COG2199	diguanylate cyclase activity
FYA48_RS15925	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FYA48_RS15960	COG2159	amidohydrolase
FYA48_RS15970	COG0583	DNA-binding transcription factor activity
FYA48_RS15985	COG1024	Enoyl-CoA hydratase
FYA48_RS15990	COG2186	Transcriptional regulator
FYA48_RS15995	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYA48_RS16005	COG0833	amino acid
FYA48_RS16015	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FYA48_RS16050	COG5265	(ABC) transporter
FYA48_RS16090	COG1971	Probably functions as a manganese efflux pump
FYA48_RS16095	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FYA48_RS16105	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FYA48_RS16145	COG4608	Belongs to the ABC transporter superfamily
FYA48_RS16165	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FYA48_RS16175	COG3383	formate dehydrogenase (NAD+) activity
FYA48_RS16190	COG0747	negative chemotaxis
FYA48_RS16200	COG0625	glutathione transferase activity
FYA48_RS16230	COG1595	DNA-templated transcription, initiation
FYA48_RS16240	COG4774	siderophore transport
FYA48_RS16255	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FYA48_RS16270	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FYA48_RS16275	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FYA48_RS16300	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYA48_RS16305	COG1024	Enoyl-CoA hydratase
FYA48_RS16340	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FYA48_RS16345	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FYA48_RS16350	COG1116	anion transmembrane transporter activity
FYA48_RS16360	COG3585	molybdate ion transport
FYA48_RS16420	COG0583	DNA-binding transcription factor activity
FYA48_RS16425	COG4948	Mandelate Racemase Muconate Lactonizing
FYA48_RS16430	COG3181	Tripartite tricarboxylate transporter family receptor
FYA48_RS16455	COG3181	Tripartite tricarboxylate transporter family receptor
FYA48_RS16460	COG3181	Tripartite tricarboxylate transporter family receptor
FYA48_RS16495	COG4177	L-phenylalanine transmembrane transporter activity
FYA48_RS16520	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FYA48_RS16535	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FYA48_RS16540	COG1538	Outer membrane efflux protein
FYA48_RS16545	COG1136	(ABC) transporter
FYA48_RS16545	COG0577	efflux transmembrane transporter activity
FYA48_RS16550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYA48_RS16565	COG0259	pyridoxamine-phosphate oxidase activity
FYA48_RS16570	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FYA48_RS16575	COG0579	oxidoreductase
FYA48_RS16585	COG0405	Gamma-glutamyltransferase
FYA48_RS16595	COG3181	Tripartite tricarboxylate transporter family receptor
FYA48_RS16605	COG0114	fumarate hydratase activity
FYA48_RS16610	COG0802	atpase or kinase
FYA48_RS16615	COG0860	N-Acetylmuramoyl-L-alanine amidase
FYA48_RS16620	COG0586	Pfam SNARE associated Golgi protein
FYA48_RS16625	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FYA48_RS16630	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FYA48_RS16635	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FYA48_RS16650	COG0617	tRNA 3'-terminal CCA addition
FYA48_RS16685	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
FYA48_RS16695	COG1024	Enoyl-CoA hydratase
FYA48_RS16705	COG2188	Transcriptional regulator
FYA48_RS16710	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FYA48_RS16725	COG0752	glycyl-tRNA synthetase alpha subunit
FYA48_RS16730	COG0751	glycine-tRNA ligase activity
FYA48_RS16735	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FYA48_RS16740	COG0204	Acyl-transferase
FYA48_RS16770	COG0242	peptide deformylase activity
FYA48_RS16780	COG0700	Nucleoside recognition
FYA48_RS16785	COG0469	pyruvate kinase activity
FYA48_RS16790	COG1929	Belongs to the glycerate kinase type-1 family
FYA48_RS16800	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FYA48_RS16805	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FYA48_RS16810	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FYA48_RS16820	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FYA48_RS16830	COG2154	pterin-4-alpha-carbinolamine dehydratase
FYA48_RS16835	COG2885	chlorophyll binding
FYA48_RS16845	COG0667	Aldo Keto reductase
FYA48_RS16855	COG3181	Tripartite tricarboxylate transporter family receptor
FYA48_RS16875	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FYA48_RS16880	COG0288	reversible hydration of carbon dioxide
FYA48_RS16900	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FYA48_RS16910	COG4829	muconolactone delta-isomerase
FYA48_RS16915	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FYA48_RS16925	COG1414	Transcriptional regulator
FYA48_RS16930	COG1028	Short-chain dehydrogenase reductase Sdr
FYA48_RS16935	COG2031	fatty acid transporter
FYA48_RS16940	COG1250	3-hydroxyacyl-CoA dehydrogenase
FYA48_RS16950	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FYA48_RS16955	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FYA48_RS16970	COG0129	dihydroxy-acid dehydratase activity
FYA48_RS16975	COG1609	Transcriptional regulator
FYA48_RS17000	COG4106	trans-aconitate 2-methyltransferase activity
FYA48_RS17015	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FYA48_RS17050	COG0163	prenyltransferase activity
FYA48_RS17055	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FYA48_RS17060	COG2890	protein-(glutamine-N5) methyltransferase activity
FYA48_RS17065	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FYA48_RS17070	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FYA48_RS17085	COG3712	iron ion homeostasis
FYA48_RS17115	COG0659	secondary active sulfate transmembrane transporter activity
FYA48_RS17135	COG1028	Short-chain dehydrogenase reductase Sdr
FYA48_RS17145	COG4774	siderophore transport
FYA48_RS17155	COG1595	DNA-templated transcription, initiation
FYA48_RS17170	COG0142	geranyltranstransferase activity
FYA48_RS17175	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FYA48_RS17180	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FYA48_RS17185	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FYA48_RS17190	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FYA48_RS17210	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FYA48_RS17210	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FYA48_RS17215	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FYA48_RS17230	COG0583	DNA-binding transcription factor activity
FYA48_RS17235	COG0861	Integral membrane protein TerC family
FYA48_RS17250	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FYA48_RS17255	COG0793	Belongs to the peptidase S41A family
FYA48_RS17260	COG4942	peptidase
FYA48_RS17265	COG0588	phosphoglycerate mutase activity
FYA48_RS17275	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FYA48_RS17280	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FYA48_RS17285	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FYA48_RS17290	COG3181	Tripartite tricarboxylate transporter family receptor
FYA48_RS17305	COG2226	methyltransferase
FYA48_RS17310	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
FYA48_RS17315	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FYA48_RS17325	COG2204	response regulator
FYA48_RS17330	COG5000	phosphorelay sensor kinase activity
FYA48_RS17340	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FYA48_RS17340	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FYA48_RS17375	COG2188	Transcriptional regulator
FYA48_RS17390	COG0583	DNA-binding transcription factor activity
FYA48_RS17395	COG1012	belongs to the aldehyde dehydrogenase family
FYA48_RS17415	COG0546	phosphoglycolate phosphatase activity
FYA48_RS17430	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FYA48_RS17435	COG0242	peptide deformylase activity
FYA48_RS17445	COG1522	sequence-specific DNA binding
FYA48_RS17450	COG2879	small protein
FYA48_RS17455	COG1966	Carbon starvation protein
FYA48_RS17485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYA48_RS17490	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FYA48_RS17495	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FYA48_RS17500	COG3181	Tripartite tricarboxylate transporter family receptor
FYA48_RS17565	COG1172	Belongs to the binding-protein-dependent transport system permease family
FYA48_RS17600	COG0640	Transcriptional regulator
FYA48_RS17640	COG0735	belongs to the Fur family
FYA48_RS17645	COG2207	Transcriptional regulator
FYA48_RS17650	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FYA48_RS17655	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FYA48_RS17660	COG0513	Belongs to the DEAD box helicase family
FYA48_RS17685	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FYA48_RS17700	COG1305	Transglutaminase-like
FYA48_RS17740	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FYA48_RS17745	COG1950	PFAM Membrane protein of
FYA48_RS17770	COG0024	Methionine aminopeptidase
FYA48_RS17775	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FYA48_RS17785	COG1560	Kdo2-lipid A biosynthetic process
FYA48_RS17790	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FYA48_RS17800	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FYA48_RS17835	COG0735	belongs to the Fur family
FYA48_RS17840	COG0523	cobalamin synthesis protein
FYA48_RS17855	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FYA48_RS17865	COG2096	Adenosyltransferase
FYA48_RS17870	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FYA48_RS17875	COG0321	lipoyl(octanoyl) transferase activity
FYA48_RS17885	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FYA48_RS17890	COG1686	Belongs to the peptidase S11 family
FYA48_RS17915	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FYA48_RS17925	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FYA48_RS17935	COG0859	PFAM glycosyl transferase family 9
FYA48_RS17970	COG0477	Major facilitator Superfamily
FYA48_RS17985	COG3568	Endonuclease Exonuclease Phosphatase
FYA48_RS17990	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FYA48_RS18020	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FYA48_RS18025	COG1956	GAF domain-containing protein
FYA48_RS18030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FYA48_RS18045	COG2186	Transcriptional regulator
FYA48_RS18050	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FYA48_RS18065	COG1840	ABC-type Fe3 transport system, periplasmic component
FYA48_RS18105	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FYA48_RS18110	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FYA48_RS18115	COG1086	Polysaccharide biosynthesis protein
FYA48_RS18145	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FYA48_RS18155	COG1028	Short-chain dehydrogenase reductase Sdr
FYA48_RS18160	COG1012	belongs to the aldehyde dehydrogenase family
FYA48_RS18185	COG1522	sequence-specific DNA binding
FYA48_RS18190	COG3781	membrane
FYA48_RS18230	COG2200	EAL domain
FYA48_RS18240	COG0592	DNA-directed DNA polymerase activity
FYA48_RS18245	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FYA48_RS18250	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FYA48_RS18255	COG0594	ribonuclease P activity
FYA48_RS18260	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FYA48_RS18265	COG0706	membrane insertase activity
FYA48_RS18270	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FYA48_RS18275	COG1473	amidohydrolase
FYA48_RS18280	COG4608	Belongs to the ABC transporter superfamily
FYA48_RS18285	COG0444	Belongs to the ABC transporter superfamily
FYA48_RS18290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FYA48_RS18295	COG0601	transmembrane transport
FYA48_RS18305	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FYA48_RS18310	COG1505	serine-type exopeptidase activity
FYA48_RS18320	COG0281	malic enzyme
FYA48_RS18320	COG0280	phosphate acetyltransferase
FYA48_RS18350	COG0436	Aminotransferase
FYA48_RS18355	COG1278	Cold shock