locus-tag	class	description
BTL47_RS00005	COG0445	tRNA wobble uridine modification
BTL47_RS00010	COG0357	Ribosomal RNA small subunit methyltransferase G
BTL47_RS00015	COG1192	Involved in chromosome partitioning
BTL47_RS00020	COG1475	DNA binding
BTL47_RS00025	COG0252	asparaginase activity
BTL47_RS00045	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BTL47_RS00055	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BTL47_RS00065	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BTL47_RS00070	COG0081	regulation of translation
BTL47_RS00075	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BTL47_RS00080	COG0222	ribosome binding
BTL47_RS00085	COG0085	RNA polymerase activity
BTL47_RS00090	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BTL47_RS00125	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BTL47_RS00130	COG0049	tRNA binding
BTL47_RS00135	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BTL47_RS00140	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BTL47_RS00145	COG0051	transcription antitermination factor activity, RNA binding
BTL47_RS00150	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BTL47_RS00155	COG0088	Forms part of the polypeptide exit tunnel
BTL47_RS00160	COG0089	rRNA binding
BTL47_RS00165	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BTL47_RS00170	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BTL47_RS00175	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BTL47_RS00180	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BTL47_RS00185	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BTL47_RS00190	COG0255	Belongs to the universal ribosomal protein uL29 family
BTL47_RS00195	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BTL47_RS00205	COG4177	L-phenylalanine transmembrane transporter activity
BTL47_RS00215	COG1129	ABC transporter
BTL47_RS00220	COG0411	ABC transporter
BTL47_RS00250	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BTL47_RS00255	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BTL47_RS00260	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BTL47_RS00265	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BTL47_RS00270	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BTL47_RS00275	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BTL47_RS00280	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BTL47_RS00285	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BTL47_RS00290	COG1841	ribosomal large subunit assembly
BTL47_RS00295	COG0200	Binds to the 23S rRNA
BTL47_RS00300	COG0201	protein transport
BTL47_RS00305	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BTL47_RS00310	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BTL47_RS00315	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BTL47_RS00320	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BTL47_RS00325	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BTL47_RS00330	COG0202	RNA polymerase activity
BTL47_RS00335	COG0203	ribosomal protein L17
BTL47_RS00340	COG0537	adenosine 5'-monophosphoramidase activity
BTL47_RS00345	COG1324	tolerance protein
BTL47_RS00350	COG4232	protein-disulfide reductase activity
BTL47_RS00365	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BTL47_RS00375	COG1333	cytochrome c biogenesis protein
BTL47_RS00380	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BTL47_RS00395	COG1965	Belongs to the frataxin family
BTL47_RS00405	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BTL47_RS00410	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BTL47_RS00415	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BTL47_RS00435	COG2814	Major facilitator Superfamily
BTL47_RS00480	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BTL47_RS00485	COG2922	Belongs to the Smg family
BTL47_RS00490	COG1629	transport
BTL47_RS00500	COG2358	TRAP transporter, solute receptor (TAXI family
BTL47_RS00510	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BTL47_RS00525	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BTL47_RS00530	COG0183	Belongs to the thiolase family
BTL47_RS00535	COG1960	acyl-CoA dehydrogenase activity
BTL47_RS00560	COG2200	EAL domain
BTL47_RS00565	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BTL47_RS00575	COG0018	arginyl-trna synthetase
BTL47_RS00590	COG0154	amidase activity
BTL47_RS00595	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BTL47_RS00605	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BTL47_RS00615	COG0697	spore germination
BTL47_RS00675	COG3350	monooxygenase activity
BTL47_RS00700	COG1309	transcriptional regulator
BTL47_RS00730	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BTL47_RS00735	COG1280	lysine exporter protein (LysE YggA)
BTL47_RS00740	COG0513	Belongs to the DEAD box helicase family
BTL47_RS00750	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BTL47_RS00755	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BTL47_RS00785	COG2969	positive regulation of protein catabolic process
BTL47_RS00790	COG0625	glutathione transferase activity
BTL47_RS00795	COG2857	Cytochrome c1
BTL47_RS00800	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BTL47_RS00805	COG0723	plastoquinol--plastocyanin reductase activity
BTL47_RS00810	COG1970	mechanosensitive ion channel activity
BTL47_RS00815	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BTL47_RS00820	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BTL47_RS00830	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BTL47_RS00835	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BTL47_RS00845	COG0140	phosphoribosyl-ATP diphosphatase activity
BTL47_RS00850	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BTL47_RS00855	COG0107	imidazoleglycerol-phosphate synthase activity
BTL47_RS00860	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BTL47_RS00870	COG0131	Imidazoleglycerol-phosphate dehydratase
BTL47_RS00875	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BTL47_RS00880	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BTL47_RS00885	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BTL47_RS00890	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BTL47_RS00895	COG0271	Belongs to the BolA IbaG family
BTL47_RS00900	COG0842	Transport permease protein
BTL47_RS00905	COG1131	(ABC) transporter
BTL47_RS00920	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BTL47_RS00925	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BTL47_RS00930	COG1127	ABC transporter
BTL47_RS00950	COG0067	glutamate synthase
BTL47_RS00950	COG0069	glutamate synthase activity
BTL47_RS00950	COG0070	glutamate synthase
BTL47_RS00975	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BTL47_RS01000	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BTL47_RS01005	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BTL47_RS01045	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BTL47_RS01080	COG0109	protoheme IX farnesyltransferase activity
BTL47_RS01085	COG1999	signal sequence binding
BTL47_RS01105	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BTL47_RS01110	COG2814	Major facilitator Superfamily
BTL47_RS01125	COG1522	sequence-specific DNA binding
BTL47_RS01185	COG4948	Mandelate Racemase Muconate Lactonizing
BTL47_RS01200	COG3119	arylsulfatase activity
BTL47_RS01240	COG0402	S-adenosylhomocysteine deaminase activity
BTL47_RS01250	COG1304	FMN binding
BTL47_RS01255	COG1254	Belongs to the acylphosphatase family
BTL47_RS01265	COG3181	Tripartite tricarboxylate transporter family receptor
BTL47_RS01275	COG1414	Transcriptional regulator
BTL47_RS01295	COG0028	Belongs to the TPP enzyme family
BTL47_RS01300	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BTL47_RS01305	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BTL47_RS01310	COG1960	acyl-CoA dehydrogenase activity
BTL47_RS01345	COG3181	Tripartite tricarboxylate transporter family receptor
BTL47_RS01350	COG0583	DNA-binding transcription factor activity
BTL47_RS01365	COG0129	dihydroxy-acid dehydratase activity
BTL47_RS01370	COG2084	Dehydrogenase
BTL47_RS01385	COG1671	Belongs to the UPF0178 family
BTL47_RS01390	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BTL47_RS01405	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BTL47_RS01410	COG0443	Heat shock 70 kDa protein
BTL47_RS01435	COG2169	Transcriptional regulator
BTL47_RS01435	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BTL47_RS01450	COG1683	Conserved Protein
BTL47_RS01455	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BTL47_RS01470	COG1120	ATPase activity
BTL47_RS01475	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTL47_RS01480	COG4558	Periplasmic binding protein
BTL47_RS01485	COG3720	iron ion transport
BTL47_RS01495	COG3712	iron ion homeostasis
BTL47_RS01500	COG1595	DNA-templated transcription, initiation
BTL47_RS01520	COG1607	acyl-coa hydrolase
BTL47_RS01530	COG3383	formate dehydrogenase (NAD+) activity
BTL47_RS01530	COG0243	molybdopterin cofactor binding
BTL47_RS01535	COG0243	molybdopterin cofactor binding
BTL47_RS01535	COG3383	formate dehydrogenase (NAD+) activity
BTL47_RS01540	COG0437	4 iron, 4 sulfur cluster binding
BTL47_RS01545	COG2864	formate dehydrogenase
BTL47_RS01560	COG3276	selenocysteine insertion sequence binding
BTL47_RS01595	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BTL47_RS01600	COG0512	Glutamine amidotransferase of anthranilate synthase
BTL47_RS01610	COG0546	phosphoglycolate phosphatase activity
BTL47_RS01615	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BTL47_RS01620	COG2967	ApaG domain
BTL47_RS01625	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
BTL47_RS01630	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BTL47_RS01635	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BTL47_RS01640	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BTL47_RS01645	COG0037	tRNA processing
BTL47_RS01665	COG1024	Enoyl-CoA hydratase
BTL47_RS01680	COG0356	it plays a direct role in the translocation of protons across the membrane
BTL47_RS01690	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BTL47_RS01695	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BTL47_RS01700	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BTL47_RS01705	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BTL47_RS01710	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BTL47_RS01715	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BTL47_RS01735	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BTL47_RS01740	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BTL47_RS01745	COG0210	DNA helicase
BTL47_RS01760	COG4608	Belongs to the ABC transporter superfamily
BTL47_RS01765	COG0444	Belongs to the ABC transporter superfamily
BTL47_RS01770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BTL47_RS01795	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BTL47_RS01800	COG1024	Enoyl-CoA hydratase
BTL47_RS01805	COG1024	Enoyl-CoA hydratase
BTL47_RS01810	COG2070	2-Nitropropane dioxygenase
BTL47_RS01825	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BTL47_RS01830	COG1250	3-hydroxyacyl-CoA dehydrogenase
BTL47_RS01850	COG2267	carboxylic ester hydrolase activity
BTL47_RS01870	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BTL47_RS01880	COG2813	Specifically methylates the guanine in position
BTL47_RS01880	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BTL47_RS01885	COG2223	nitrite transmembrane transporter activity
BTL47_RS01890	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BTL47_RS01905	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BTL47_RS01910	COG0708	Exodeoxyribonuclease III
BTL47_RS01915	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BTL47_RS01920	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BTL47_RS01925	COG0154	amidase activity
BTL47_RS01930	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BTL47_RS01935	COG1077	Cell shape determining protein MreB Mrl
BTL47_RS01940	COG1792	Involved in formation and maintenance of cell shape
BTL47_RS01950	COG0768	penicillin binding
BTL47_RS01955	COG0772	Belongs to the SEDS family
BTL47_RS01960	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BTL47_RS01965	COG0471	metal ion transport
BTL47_RS01970	COG1309	transcriptional regulator
BTL47_RS01980	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BTL47_RS01995	COG2823	Periplasmic or secreted lipoprotein
BTL47_RS02000	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BTL47_RS02005	COG0792	nuclease activity
BTL47_RS02025	COG1660	Displays ATPase and GTPase activities
BTL47_RS02040	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BTL47_RS02050	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BTL47_RS02060	COG3181	Tripartite tricarboxylate transporter family receptor
BTL47_RS02065	COG1473	amidohydrolase
BTL47_RS02070	COG1137	ATPase activity
BTL47_RS02085	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BTL47_RS02095	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BTL47_RS02115	COG1294	oxidase, subunit
BTL47_RS02125	COG4988	ABC transporter
BTL47_RS02130	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BTL47_RS02135	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BTL47_RS02150	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BTL47_RS02155	COG1238	metal cluster binding
BTL47_RS02165	COG1802	Transcriptional regulator
BTL47_RS02175	COG1984	allophanate hydrolase subunit 2
BTL47_RS02180	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BTL47_RS02190	COG0583	DNA-binding transcription factor activity
BTL47_RS02195	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BTL47_RS02200	COG5002	protein histidine kinase activity
BTL47_RS02205	COG0745	RESPONSE REGULATOR receiver
BTL47_RS02210	COG2226	methyltransferase
BTL47_RS02255	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BTL47_RS02265	COG1028	Short-chain dehydrogenase reductase Sdr
BTL47_RS02285	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BTL47_RS02290	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BTL47_RS02300	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BTL47_RS02320	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BTL47_RS02325	COG1538	Outer membrane efflux protein
BTL47_RS02335	COG0351	phosphomethylpyrimidine kinase
BTL47_RS02340	COG2022	thiamine diphosphate biosynthetic process
BTL47_RS02345	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BTL47_RS02365	COG2226	methyltransferase
BTL47_RS02375	COG1194	a g-specific adenine glycosylase
BTL47_RS02385	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BTL47_RS02390	COG2177	Part of the ABC transporter FtsEX involved in
BTL47_RS02395	COG2884	Cell division ATP-binding protein ftsE
BTL47_RS02400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTL47_RS02405	COG4597	amino acid ABC transporter
BTL47_RS02410	COG0765	amino acid transport
BTL47_RS02415	COG1126	abc transporter atp-binding protein
BTL47_RS02435	COG0477	Major facilitator Superfamily
BTL47_RS02445	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BTL47_RS02450	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BTL47_RS02465	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BTL47_RS02470	COG0237	dephospho-CoA kinase activity
BTL47_RS02475	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
BTL47_RS02485	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BTL47_RS02500	COG3539	Fimbrial protein
BTL47_RS02505	COG3539	Fimbrial protein
BTL47_RS02520	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BTL47_RS02530	COG1846	Transcriptional regulator
BTL47_RS02595	COG1028	Short-chain dehydrogenase reductase Sdr
BTL47_RS02600	COG1024	Enoyl-CoA hydratase
BTL47_RS02605	COG1960	acyl-CoA dehydrogenase activity
BTL47_RS02635	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BTL47_RS02640	COG0352	thiamine-phosphate diphosphorylase activity
BTL47_RS02645	COG0351	phosphomethylpyrimidine kinase
BTL47_RS02655	COG1678	Uncharacterized ACR, COG1678
BTL47_RS02660	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BTL47_RS02685	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BTL47_RS02695	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BTL47_RS02700	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BTL47_RS02710	COG0557	exoribonuclease II activity
BTL47_RS02720	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BTL47_RS02725	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BTL47_RS02730	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BTL47_RS02740	COG0439	Biotin carboxylase
BTL47_RS02745	COG2264	protein methyltransferase activity
BTL47_RS02755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BTL47_RS02780	COG1696	Membrane protein involved in D-alanine export
BTL47_RS02785	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BTL47_RS02815	COG1522	sequence-specific DNA binding
BTL47_RS02830	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BTL47_RS02895	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BTL47_RS02920	COG3028	Belongs to the UPF0307 family
BTL47_RS02925	COG0312	modulator of DNA gyrase
BTL47_RS02930	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BTL47_RS02935	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BTL47_RS02940	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BTL47_RS02950	COG0316	Belongs to the HesB IscA family
BTL47_RS02960	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BTL47_RS02970	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BTL47_RS02975	COG1881	PFAM PEBP family protein
BTL47_RS02980	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BTL47_RS02985	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BTL47_RS03000	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BTL47_RS03000	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BTL47_RS03015	COG2718	Belongs to the UPF0229 family
BTL47_RS03020	COG2719	SpoVR family
BTL47_RS03085	COG0165	Argininosuccinate lyase
BTL47_RS03090	COG0589	response to stress
BTL47_RS03100	COG2816	NAD+ diphosphatase activity
BTL47_RS03105	COG4993	Dehydrogenase
BTL47_RS03130	COG3181	Tripartite tricarboxylate transporter family receptor
BTL47_RS03135	COG2979	Protein of unknown function (DUF533)
BTL47_RS03140	COG4206	TonB-dependent receptor
BTL47_RS03155	COG1388	LysM domain
BTL47_RS03155	COG0741	lytic transglycosylase activity
BTL47_RS03160	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTL47_RS03165	COG2226	methyltransferase
BTL47_RS03170	COG0328	RNA-DNA hybrid ribonuclease activity
BTL47_RS03195	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BTL47_RS03215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BTL47_RS03220	COG1129	ABC transporter
BTL47_RS03220	COG0842	Transport permease protein
BTL47_RS03225	COG0842	Transport permease protein
BTL47_RS03245	COG0463	Glycosyl transferase, family 2
BTL47_RS03250	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BTL47_RS03265	COG1073	alpha beta
BTL47_RS03275	COG0697	spore germination
BTL47_RS03280	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTL47_RS03305	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BTL47_RS03335	COG0823	Involved in the tonB-independent uptake of proteins
BTL47_RS03345	COG0848	biopolymer transport protein
BTL47_RS03350	COG0811	peptide transport
BTL47_RS03355	COG0824	Thioesterase
BTL47_RS03360	COG0442	prolyl-tRNA aminoacylation
BTL47_RS03405	COG2084	Dehydrogenase
BTL47_RS03450	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BTL47_RS03455	COG4654	Cytochrome c, class I
BTL47_RS03460	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BTL47_RS03525	COG1473	amidohydrolase
BTL47_RS03530	COG0418	dihydroorotase activity
BTL47_RS03535	COG0488	(ABC) transporter
BTL47_RS03545	COG2001	Belongs to the MraZ family
BTL47_RS03550	COG0275	rRNA processing
BTL47_RS03555	COG3116	cell division
BTL47_RS03565	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BTL47_RS03570	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BTL47_RS03575	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BTL47_RS03585	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BTL47_RS03590	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BTL47_RS03595	COG1181	Belongs to the D-alanine--D-alanine ligase family
BTL47_RS03600	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BTL47_RS03615	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BTL47_RS03630	COG0739	heme binding
BTL47_RS03635	COG0653	protein targeting
BTL47_RS03660	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BTL47_RS03665	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BTL47_RS03675	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BTL47_RS03715	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BTL47_RS03730	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
BTL47_RS03755	COG0583	DNA-binding transcription factor activity
BTL47_RS03765	COG3181	Tripartite tricarboxylate transporter family receptor
BTL47_RS03770	COG2084	Dehydrogenase
BTL47_RS03780	COG1597	lipid kinase activity
BTL47_RS03780	COG1803	Methylglyoxal synthase
BTL47_RS03790	COG0671	phosphoesterase, PA-phosphatase related
BTL47_RS03810	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BTL47_RS03815	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BTL47_RS03820	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BTL47_RS03825	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BTL47_RS03830	COG0649	NAD binding
BTL47_RS03835	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BTL47_RS03845	COG1034	ATP synthesis coupled electron transport
BTL47_RS03850	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BTL47_RS03855	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BTL47_RS03865	COG0713	ATP synthesis coupled electron transport
BTL47_RS03880	COG1007	ATP synthesis coupled electron transport
BTL47_RS03890	COG0560	Phosphoserine phosphatase
BTL47_RS03895	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BTL47_RS03900	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BTL47_RS03905	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BTL47_RS03920	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BTL47_RS03925	COG0450	alkyl hydroperoxide reductase
BTL47_RS03945	COG1214	PFAM Peptidase M22, glycoprotease
BTL47_RS03950	COG1573	uracil-dna glycosylase
BTL47_RS03955	COG0477	Major facilitator Superfamily
BTL47_RS03960	COG1196	nuclear chromosome segregation
BTL47_RS03970	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BTL47_RS03975	COG1126	abc transporter atp-binding protein
BTL47_RS03980	COG0765	amino acid transport
BTL47_RS03985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTL47_RS03990	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BTL47_RS03995	COG2917	probably involved in intracellular septation
BTL47_RS04000	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BTL47_RS04005	COG1122	ATPase activity
BTL47_RS04010	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BTL47_RS04045	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BTL47_RS04070	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BTL47_RS04075	COG2878	Part of a membrane complex involved in electron transport
BTL47_RS04095	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BTL47_RS04100	COG0251	oxidation-reduction process
BTL47_RS04110	COG3228	Belongs to the MtfA family
BTL47_RS04115	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BTL47_RS04125	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BTL47_RS04135	COG0159	tryptophan synthase activity
BTL47_RS04140	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BTL47_RS04145	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BTL47_RS04160	COG1530	ribonuclease E activity
BTL47_RS04165	COG0564	pseudouridine synthase activity
BTL47_RS04170	COG0546	phosphoglycolate phosphatase activity
BTL47_RS04175	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BTL47_RS04180	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
BTL47_RS04185	COG3023	N-Acetylmuramoyl-L-alanine amidase
BTL47_RS04195	COG0424	maF-like protein
BTL47_RS04205	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BTL47_RS04215	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BTL47_RS04225	COG1028	Short-chain dehydrogenase reductase Sdr
BTL47_RS04230	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BTL47_RS04235	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BTL47_RS04260	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BTL47_RS04280	COG0481	GTPase activity
BTL47_RS04285	COG0681	Belongs to the peptidase S26 family
BTL47_RS04290	COG0571	ribonuclease III activity
BTL47_RS04295	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BTL47_RS04300	COG1381	Involved in DNA repair and RecF pathway recombination
BTL47_RS04330	COG0670	Belongs to the BI1 family
BTL47_RS04345	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BTL47_RS04370	COG0583	DNA-binding transcription factor activity
BTL47_RS04390	COG0791	NLP P60 protein
BTL47_RS04395	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BTL47_RS04400	COG3193	protein, possibly involved in utilization of glycolate and propanediol
BTL47_RS04410	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BTL47_RS04430	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
BTL47_RS04465	COG1446	asparaginase
BTL47_RS04470	COG4172	Belongs to the ABC transporter superfamily
BTL47_RS04475	COG0747	negative chemotaxis
BTL47_RS04480	COG0601	transmembrane transport
BTL47_RS04505	COG0504	CTP synthase activity
BTL47_RS04515	COG0148	phosphopyruvate hydratase activity
BTL47_RS04530	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BTL47_RS04540	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BTL47_RS04545	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BTL47_RS04590	COG1981	membrane
BTL47_RS04610	COG0039	L-malate dehydrogenase activity
BTL47_RS04615	COG2188	Transcriptional regulator
BTL47_RS04620	COG2009	succinate dehydrogenase
BTL47_RS04625	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BTL47_RS04630	COG1053	succinate dehydrogenase
BTL47_RS04635	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BTL47_RS04640	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BTL47_RS04645	COG0372	Belongs to the citrate synthase family
BTL47_RS04660	COG0583	DNA-binding transcription factor activity
BTL47_RS04665	COG3842	ATPase activity
BTL47_RS04685	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BTL47_RS04695	COG3128	pkhd-type hydroxylase
BTL47_RS04700	COG4774	siderophore transport
BTL47_RS04710	COG0280	phosphate acetyltransferase
BTL47_RS04710	COG0281	malic enzyme
BTL47_RS04720	COG1297	OPT oligopeptide transporter protein
BTL47_RS04725	COG0567	Dehydrogenase, E1 component
BTL47_RS04730	COG0508	dehydrogenase complex catalyzes the overall conversion of
BTL47_RS04735	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BTL47_RS04740	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BTL47_RS04745	COG1595	DNA-templated transcription, initiation
BTL47_RS04755	COG4774	siderophore transport
BTL47_RS04780	COG2183	response to ionizing radiation
BTL47_RS04785	COG1199	ATP-dependent helicase activity
BTL47_RS04795	COG0564	pseudouridine synthase activity
BTL47_RS04805	COG3243	poly(R)-hydroxyalkanoic acid synthase
BTL47_RS04810	COG1028	Short-chain dehydrogenase reductase Sdr
BTL47_RS04815	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
BTL47_RS04830	COG0672	)-iron permease
BTL47_RS04845	COG2823	Periplasmic or secreted lipoprotein
BTL47_RS04865	COG3237	CsbD-like
BTL47_RS04870	COG3038	cytochrome b561
BTL47_RS04885	COG1132	(ABC) transporter
BTL47_RS04915	COG2833	Protein of unknown function (DUF455)
BTL47_RS04920	COG2951	lytic endotransglycosylase activity
BTL47_RS04945	COG0586	Pfam SNARE associated Golgi protein
BTL47_RS04985	COG0165	Argininosuccinate lyase
BTL47_RS05005	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BTL47_RS05020	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BTL47_RS05025	COG1605	Chorismate mutase
BTL47_RS05025	COG0077	Prephenate dehydratase
BTL47_RS05030	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BTL47_RS05040	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BTL47_RS05045	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BTL47_RS05065	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BTL47_RS05070	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BTL47_RS05075	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BTL47_RS05080	COG0587	DNA-directed DNA polymerase activity
BTL47_RS05090	COG2951	lytic endotransglycosylase activity
BTL47_RS05095	COG0123	including yeast histone deacetylase and acetoin utilization protein
BTL47_RS05110	COG2985	domain, Protein
BTL47_RS05115	COG1960	acyl-CoA dehydrogenase activity
BTL47_RS05120	COG0450	alkyl hydroperoxide reductase
BTL47_RS05125	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BTL47_RS05130	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BTL47_RS05135	COG4208	sulfate ABC transporter
BTL47_RS05140	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BTL47_RS05145	COG0175	sulfate reduction
BTL47_RS05170	COG0335	large ribosomal subunit rRNA binding
BTL47_RS05190	COG3622	Belongs to the hyi family
BTL47_RS05195	COG1162	GTPase activity
BTL47_RS05200	COG0501	Belongs to the peptidase M48B family
BTL47_RS05205	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BTL47_RS05210	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BTL47_RS05215	COG3327	negative regulation of DNA-templated transcription, initiation
BTL47_RS05220	COG3396	Phenylacetate-CoA oxygenase
BTL47_RS05225	COG3460	Phenylacetate-CoA oxygenase
BTL47_RS05230	COG3396	Phenylacetate-CoA oxygenase
BTL47_RS05235	COG2151	metal-sulfur cluster biosynthetic enzyme
BTL47_RS05240	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BTL47_RS05245	COG1012	belongs to the aldehyde dehydrogenase family
BTL47_RS05250	COG1024	Enoyl-CoA hydratase
BTL47_RS05255	COG2050	protein possibly involved in aromatic compounds catabolism
BTL47_RS05290	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BTL47_RS05290	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BTL47_RS05300	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BTL47_RS05305	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BTL47_RS05310	COG2346	COG2346, Truncated hemoglobins
BTL47_RS05315	COG3642	lipopolysaccharide core region biosynthetic process
BTL47_RS05325	COG3842	ATPase activity
BTL47_RS05330	COG1176	ABC-type spermidine putrescine transport system, permease component I
BTL47_RS05335	COG1177	transmembrane transport
BTL47_RS05355	COG1322	Protein conserved in bacteria
BTL47_RS05365	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BTL47_RS05370	COG0704	Plays a role in the regulation of phosphate uptake
BTL47_RS05375	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
BTL47_RS05380	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BTL47_RS05380	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BTL47_RS05385	COG1643	Atp-dependent helicase
BTL47_RS05400	COG0438	transferase activity, transferring glycosyl groups
BTL47_RS05405	COG0726	polysaccharide deacetylase
BTL47_RS05410	COG0463	Glycosyl transferase, family 2
BTL47_RS05445	COG1132	(ABC) transporter
BTL47_RS05465	COG0501	Belongs to the peptidase M48B family
BTL47_RS05515	COG1722	exodeoxyribonuclease VII activity
BTL47_RS05520	COG0142	geranyltranstransferase activity
BTL47_RS05525	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BTL47_RS05530	COG1469	GTP cyclohydrolase I activity
BTL47_RS05535	COG0360	Binds together with S18 to 16S ribosomal RNA
BTL47_RS05540	COG2965	DNA replication, synthesis of RNA primer
BTL47_RS05545	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BTL47_RS05550	COG0359	binds to the 23S rRNA
BTL47_RS05560	COG0305	Participates in initiation and elongation during chromosome replication
BTL47_RS05570	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BTL47_RS05575	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BTL47_RS05580	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BTL47_RS05585	COG3737	Protein of unknown function (DUF498/DUF598)
BTL47_RS05590	COG0436	Aminotransferase
BTL47_RS05615	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BTL47_RS05620	COG0308	aminopeptidase N
BTL47_RS05635	COG0312	modulator of DNA gyrase
BTL47_RS05640	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BTL47_RS05665	COG0277	FAD linked oxidase domain protein
BTL47_RS05670	COG0277	FAD linked oxidase domain protein
BTL47_RS05675	COG0247	lactate metabolic process
BTL47_RS05715	COG0583	DNA-binding transcription factor activity
BTL47_RS05720	COG0482	sulfurtransferase activity
BTL47_RS05725	COG0730	response to heat
BTL47_RS05730	COG0625	glutathione transferase activity
BTL47_RS05735	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BTL47_RS05740	COG3909	cytochrome
BTL47_RS05775	COG3706	GGDEF domain
BTL47_RS05790	COG2826	transposase and inactivated derivatives, IS30 family
BTL47_RS05810	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
BTL47_RS05835	COG0069	glutamate synthase activity
BTL47_RS05840	COG2391	methyltransferase activity
BTL47_RS05845	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BTL47_RS05850	COG0679	Auxin Efflux Carrier
BTL47_RS05855	COG2153	protein acetylation
BTL47_RS05875	COG0557	exoribonuclease II activity
BTL47_RS05880	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BTL47_RS05885	COG2873	o-acetylhomoserine
BTL47_RS05890	COG0776	regulation of translation
BTL47_RS05920	COG0642	Histidine kinase
BTL47_RS05925	COG3158	transport of potassium into the cell
BTL47_RS05950	COG0137	argininosuccinate synthase activity
BTL47_RS05955	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BTL47_RS05960	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BTL47_RS05970	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BTL47_RS05985	COG2186	Transcriptional regulator
BTL47_RS06020	COG3836	Belongs to the HpcH HpaI aldolase family
BTL47_RS06025	COG0268	Binds directly to 16S ribosomal RNA
BTL47_RS06075	COG0728	peptidoglycan biosynthetic process
BTL47_RS06085	COG0563	adenylate kinase activity
BTL47_RS06090	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BTL47_RS06095	COG2835	tetraacyldisaccharide 4'-kinase activity
BTL47_RS06100	COG1663	tetraacyldisaccharide 4'-kinase activity
BTL47_RS06105	COG0848	biopolymer transport protein
BTL47_RS06110	COG0811	peptide transport
BTL47_RS06115	COG1570	exodeoxyribonuclease VII activity
BTL47_RS06120	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BTL47_RS06130	COG0038	chloride channel
BTL47_RS06135	COG0183	Belongs to the thiolase family
BTL47_RS06145	COG1278	Cold shock
BTL47_RS06150	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BTL47_RS06160	COG4953	penicillin-binding protein 1C
BTL47_RS06175	COG3008	intermembrane lipid transfer
BTL47_RS06185	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BTL47_RS06185	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BTL47_RS06185	COG0506	proline dehydrogenase activity
BTL47_RS06220	COG0004	ammonium transporteR
BTL47_RS06225	COG0347	Belongs to the P(II) protein family
BTL47_RS06265	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BTL47_RS06270	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BTL47_RS06275	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BTL47_RS06280	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BTL47_RS06280	COG0072	phenylalanine-tRNA ligase activity
BTL47_RS06285	COG0776	regulation of translation
BTL47_RS06315	COG1802	Transcriptional regulator
BTL47_RS06320	COG3181	Tripartite tricarboxylate transporter family receptor
BTL47_RS06340	COG1278	Cold shock
BTL47_RS06350	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BTL47_RS06370	COG1522	sequence-specific DNA binding
BTL47_RS06420	COG5265	(ABC) transporter
BTL47_RS06440	COG0656	L-ascorbic acid biosynthetic process
BTL47_RS06445	COG0667	Aldo Keto reductase
BTL47_RS06460	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BTL47_RS06505	COG1610	YqeY-like protein
BTL47_RS06520	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BTL47_RS06525	COG3246	L-lysine catabolic process to acetate
BTL47_RS06545	COG0318	PFAM AMP-dependent synthetase and ligase
BTL47_RS06560	COG0183	Belongs to the thiolase family
BTL47_RS06565	COG1250	3-hydroxyacyl-CoA dehydrogenase
BTL47_RS06565	COG1024	Enoyl-CoA hydratase
BTL47_RS06575	COG1024	Enoyl-CoA hydratase
BTL47_RS06575	COG1250	3-hydroxyacyl-CoA dehydrogenase
BTL47_RS06580	COG0183	Belongs to the thiolase family
BTL47_RS06585	COG1960	acyl-CoA dehydrogenase activity
BTL47_RS06595	COG1045	serine acetyltransferase
BTL47_RS06605	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BTL47_RS06610	COG0483	inositol monophosphate 1-phosphatase activity
BTL47_RS06615	COG1012	belongs to the aldehyde dehydrogenase family
BTL47_RS06620	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BTL47_RS06635	COG0210	DNA helicase
BTL47_RS06640	COG0598	Magnesium transport protein CorA
BTL47_RS06650	COG0747	negative chemotaxis
BTL47_RS06655	COG0601	transmembrane transport
BTL47_RS06660	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BTL47_RS06665	COG4172	Belongs to the ABC transporter superfamily
BTL47_RS06685	COG1346	cytolysis
BTL47_RS06695	COG1028	Short-chain dehydrogenase reductase Sdr
BTL47_RS06700	COG0783	Belongs to the Dps family
BTL47_RS06720	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BTL47_RS06730	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BTL47_RS06735	COG1845	cytochrome c oxidase, subunit III
BTL47_RS06740	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BTL47_RS06785	COG1666	GTP binding
BTL47_RS06810	COG1028	Short-chain dehydrogenase reductase Sdr
BTL47_RS06815	COG5006	permease, DMT superfamily
BTL47_RS06840	COG2264	protein methyltransferase activity
BTL47_RS06875	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BTL47_RS06880	COG0746	molybdenum cofactor guanylyltransferase activity
BTL47_RS06885	COG0303	'Molybdopterin
BTL47_RS06890	COG0521	Mo-molybdopterin cofactor biosynthetic process
BTL47_RS06895	COG0314	molybdopterin synthase activity
BTL47_RS06905	COG0315	cyclic pyranopterin monophosphate synthase activity
BTL47_RS06910	COG0412	Dienelactone hydrolase
BTL47_RS06920	COG0678	peroxiredoxin activity
BTL47_RS06935	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BTL47_RS06945	COG0542	response to heat
BTL47_RS06955	COG1477	protein flavinylation
BTL47_RS06980	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BTL47_RS06985	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
BTL47_RS06985	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
BTL47_RS06990	COG1562	ergosterol biosynthetic process
BTL47_RS06995	COG1562	ergosterol biosynthetic process
BTL47_RS07000	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BTL47_RS07040	COG0254	rRNA binding
BTL47_RS07045	COG3483	tryptophan 2,3-dioxygenase activity
BTL47_RS07050	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BTL47_RS07055	COG2003	Belongs to the UPF0758 family
BTL47_RS07065	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BTL47_RS07070	COG0625	glutathione transferase activity
BTL47_RS07090	COG0523	cobalamin synthesis protein
BTL47_RS07100	COG0583	DNA-binding transcription factor activity
BTL47_RS07110	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BTL47_RS07115	COG1187	pseudouridine synthase activity
BTL47_RS07120	COG0779	Required for maturation of 30S ribosomal subunits
BTL47_RS07125	COG0195	Participates in both transcription termination and antitermination
BTL47_RS07125	COG2251	uridine kinase activity
BTL47_RS07130	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BTL47_RS07135	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BTL47_RS07140	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BTL47_RS07145	COG1217	gtp-binding protein TYPA
BTL47_RS07160	COG1802	Transcriptional regulator
BTL47_RS07170	COG1024	Enoyl-CoA hydratase
BTL47_RS07175	COG0318	PFAM AMP-dependent synthetase and ligase
BTL47_RS07185	COG2032	superoxide dismutase activity
BTL47_RS07200	COG4120	Belongs to the binding-protein-dependent transport system permease family
BTL47_RS07205	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BTL47_RS07210	COG0725	ABC transporter, periplasmic molybdate-binding protein
BTL47_RS07215	COG4149	molybdate abc transporter
BTL47_RS07245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BTL47_RS07250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BTL47_RS07255	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BTL47_RS07265	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BTL47_RS07270	COG0736	holo-[acyl-carrier-protein] synthase activity
BTL47_RS07275	COG1472	Belongs to the glycosyl hydrolase 3 family
BTL47_RS07280	COG0322	excinuclease ABC activity
BTL47_RS07285	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BTL47_RS07295	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BTL47_RS07295	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BTL47_RS07300	COG2224	Isocitrate lyase
BTL47_RS07305	COG1846	Transcriptional regulator
BTL47_RS07310	COG1764	response to oxidative stress
BTL47_RS07315	COG1131	(ABC) transporter
BTL47_RS07325	COG0628	permease
BTL47_RS07340	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
BTL47_RS07350	COG2814	Major facilitator Superfamily
BTL47_RS07370	COG3015	lipoprotein NlpE involved in copper resistance
BTL47_RS07380	COG3530	Putative quorum-sensing-regulated virulence factor
BTL47_RS07395	COG0494	nUDIX hydrolase
BTL47_RS07405	COG0697	spore germination
BTL47_RS07410	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BTL47_RS07435	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BTL47_RS07440	COG1702	phosphate starvation-inducible protein PhoH
BTL47_RS07445	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BTL47_RS07450	COG4535	Mg2 and Co2 transporter CorC
BTL47_RS07455	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BTL47_RS07460	COG0667	Aldo Keto reductase
BTL47_RS07480	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BTL47_RS07485	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BTL47_RS07490	COG1862	Preprotein translocase
BTL47_RS07495	COG0343	queuine tRNA-ribosyltransferase activity
BTL47_RS07500	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BTL47_RS07505	COG2027	D-alanyl-D-alanine carboxypeptidase
BTL47_RS07510	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BTL47_RS07515	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BTL47_RS07515	COG1648	precorrin-2 dehydrogenase activity
BTL47_RS07525	COG4575	ribosome binding
BTL47_RS07550	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BTL47_RS07555	COG0741	lytic transglycosylase activity
BTL47_RS07560	COG0436	Aminotransferase
BTL47_RS07570	COG0280	phosphate acetyltransferase
BTL47_RS07570	COG0281	malic enzyme
BTL47_RS07585	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BTL47_RS07590	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BTL47_RS07595	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BTL47_RS07600	COG0126	phosphoglycerate kinase activity
BTL47_RS07615	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BTL47_RS07630	COG0625	glutathione transferase activity
BTL47_RS07650	COG0789	Transcriptional regulator
BTL47_RS07665	COG0306	phosphate transporter
BTL47_RS07670	COG0521	Mo-molybdopterin cofactor biosynthetic process
BTL47_RS07680	COG0739	heme binding
BTL47_RS07690	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BTL47_RS07730	COG0456	acetyltransferase
BTL47_RS07735	COG1301	dicarboxylic acid transport
BTL47_RS07745	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BTL47_RS07750	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BTL47_RS07755	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BTL47_RS07760	COG0009	L-threonylcarbamoyladenylate synthase
BTL47_RS07770	COG4771	TonB-dependent receptor
BTL47_RS07800	COG1960	acyl-CoA dehydrogenase activity
BTL47_RS07805	COG0028	Belongs to the TPP enzyme family
BTL47_RS07810	COG0583	DNA-binding transcription factor activity
BTL47_RS07815	COG4974	Belongs to the 'phage' integrase family
BTL47_RS07820	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BTL47_RS07825	COG1686	Belongs to the peptidase S11 family
BTL47_RS07855	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BTL47_RS07860	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BTL47_RS07865	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BTL47_RS07885	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BTL47_RS07890	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BTL47_RS07895	COG0505	Belongs to the CarA family
BTL47_RS07900	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BTL47_RS07910	COG1028	Short-chain dehydrogenase reductase Sdr
BTL47_RS07915	COG0406	alpha-ribazole phosphatase activity
BTL47_RS07945	COG2233	PERMEase
BTL47_RS07950	COG3620	sequence-specific DNA binding
BTL47_RS07965	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BTL47_RS07975	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BTL47_RS07980	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BTL47_RS07990	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BTL47_RS08005	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BTL47_RS08025	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BTL47_RS08085	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTL47_RS08120	COG0540	Belongs to the ATCase OTCase family
BTL47_RS08125	COG2974	May be involved in recombination
BTL47_RS08150	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BTL47_RS08155	COG2137	regulation of response to DNA damage stimulus
BTL47_RS08165	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BTL47_RS08185	COG0045	succinate-CoA ligase (ADP-forming) activity
BTL47_RS08190	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BTL47_RS08195	COG0861	Integral membrane protein TerC family
BTL47_RS08200	COG0861	Integral membrane protein TerC family
BTL47_RS08205	COG0181	hydroxymethylbilane synthase activity
BTL47_RS08245	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BTL47_RS08290	COG1450	Type ii and iii secretion system protein
BTL47_RS08335	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BTL47_RS08345	COG1295	ribonuclease BN
BTL47_RS08355	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BTL47_RS08375	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BTL47_RS08380	COG0501	Belongs to the peptidase M48B family
BTL47_RS08385	COG2197	response regulator
BTL47_RS08410	COG0066	3-isopropylmalate dehydratase activity
BTL47_RS08425	COG0473	3-isopropylmalate dehydrogenase activity
BTL47_RS08430	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BTL47_RS08440	COG0101	tRNA pseudouridine synthase activity
BTL47_RS08445	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BTL47_RS08450	COG0135	phosphoribosylanthranilate isomerase activity
BTL47_RS08470	COG2801	Transposase and inactivated derivatives
BTL47_RS08475	COG2801	Transposase and inactivated derivatives
BTL47_RS08510	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BTL47_RS08515	COG2197	response regulator
BTL47_RS08520	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BTL47_RS08525	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BTL47_RS08540	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BTL47_RS08545	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BTL47_RS08555	COG1764	response to oxidative stress
BTL47_RS08570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTL47_RS08575	COG0765	amino acid transport
BTL47_RS08580	COG0765	amino acid transport
BTL47_RS08585	COG1126	abc transporter atp-binding protein
BTL47_RS08590	COG0756	dUTP diphosphatase activity
BTL47_RS08620	COG1522	sequence-specific DNA binding
BTL47_RS08640	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BTL47_RS08645	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BTL47_RS08650	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BTL47_RS08655	COG0196	riboflavin kinase activity
BTL47_RS08665	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BTL47_RS08665	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BTL47_RS08695	COG0210	DNA helicase
BTL47_RS08700	COG4771	TonB-dependent receptor
BTL47_RS08710	COG2890	protein-(glutamine-N5) methyltransferase activity
BTL47_RS08715	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BTL47_RS08720	COG2171	N-acyltransferase activity
BTL47_RS08775	COG2801	Transposase and inactivated derivatives
BTL47_RS08820	COG2814	Major facilitator Superfamily
BTL47_RS08845	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BTL47_RS08850	COG2900	Belongs to the SlyX family
BTL47_RS08865	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BTL47_RS08885	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BTL47_RS08910	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BTL47_RS08915	COG0583	DNA-binding transcription factor activity
BTL47_RS08920	COG1028	Short-chain dehydrogenase reductase Sdr
BTL47_RS08930	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BTL47_RS08935	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BTL47_RS08945	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BTL47_RS08950	COG0508	dehydrogenase complex catalyzes the overall conversion of
BTL47_RS08955	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BTL47_RS08965	COG4566	intracellular signal transduction
BTL47_RS08970	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BTL47_RS08990	COG1999	signal sequence binding
BTL47_RS09010	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BTL47_RS09015	COG0583	DNA-binding transcription factor activity
BTL47_RS09020	COG1187	pseudouridine synthase activity
BTL47_RS09025	COG3161	chorismate lyase activity
BTL47_RS09040	COG1280	lysine exporter protein (LysE YggA)
BTL47_RS09075	COG1129	ABC transporter
BTL47_RS09090	COG0583	DNA-binding transcription factor activity
BTL47_RS09120	COG1185	polyribonucleotide nucleotidyltransferase activity
BTL47_RS09125	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BTL47_RS09140	COG1183	phosphatidylcholine synthase activity
BTL47_RS09150	COG0440	acetolactate synthase activity
BTL47_RS09155	COG0028	Belongs to the TPP enzyme family
BTL47_RS09180	COG3022	response to hydroperoxide
BTL47_RS09190	COG1028	Short-chain dehydrogenase reductase Sdr
BTL47_RS09205	COG3486	L-lysine 6-monooxygenase (NADPH) activity
BTL47_RS09235	COG2814	Major facilitator Superfamily
BTL47_RS09265	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BTL47_RS09300	COG2733	membrane
BTL47_RS09320	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BTL47_RS09340	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BTL47_RS09345	COG1129	ABC transporter
BTL47_RS09345	COG0842	Transport permease protein
BTL47_RS09350	COG0842	Transport permease protein
BTL47_RS09360	COG1028	Short-chain dehydrogenase reductase Sdr
BTL47_RS09370	COG2259	Doxx family
BTL47_RS09400	COG0415	Belongs to the DNA photolyase family
BTL47_RS09420	COG0386	Belongs to the glutathione peroxidase family
BTL47_RS09435	COG0095	Lipoate-protein ligase
BTL47_RS09445	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BTL47_RS09455	COG0010	Belongs to the arginase family
BTL47_RS09465	COG0765	amino acid transport
BTL47_RS09470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTL47_RS09485	COG0084	hydrolase, TatD family'
BTL47_RS09495	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BTL47_RS09500	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BTL47_RS09510	COG2175	clavaminate synthase activity
BTL47_RS09515	COG0583	DNA-binding transcription factor activity
BTL47_RS09540	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BTL47_RS09555	COG2914	Belongs to the UPF0125 (RnfH) family
BTL47_RS09565	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BTL47_RS09595	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BTL47_RS09595	COG0519	Catalyzes the synthesis of GMP from XMP
BTL47_RS09605	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BTL47_RS09615	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BTL47_RS09620	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BTL47_RS09625	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BTL47_RS09635	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BTL47_RS09640	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BTL47_RS09650	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BTL47_RS09655	COG0750	zinc metalloprotease
BTL47_RS09660	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BTL47_RS09670	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BTL47_RS09675	COG0233	cytoplasmic translational termination
BTL47_RS09680	COG0528	UMP kinase activity
BTL47_RS09685	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BTL47_RS09690	COG0052	Belongs to the universal ribosomal protein uS2 family
BTL47_RS09695	COG0024	Methionine aminopeptidase
BTL47_RS09700	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BTL47_RS09725	COG1286	toxin biosynthetic process
BTL47_RS09735	COG0285	dihydrofolate synthase activity
BTL47_RS09745	COG3181	Tripartite tricarboxylate transporter family receptor
BTL47_RS09750	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BTL47_RS09790	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BTL47_RS09800	COG1677	Flagellar hook-basal body complex protein FliE
BTL47_RS09810	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BTL47_RS09815	COG1317	bacterial-type flagellum organization
BTL47_RS09835	COG1580	Controls the rotational direction of flagella during chemotaxis
BTL47_RS09845	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BTL47_RS09870	COG0840	transmembrane signaling receptor activity
BTL47_RS09875	COG0840	transmembrane signaling receptor activity
BTL47_RS09900	COG1191	sigma factor activity
BTL47_RS09940	COG2199	diguanylate cyclase activity
BTL47_RS09940	COG2203	Gaf domain
BTL47_RS09950	COG1619	proteins homologs of microcin C7 resistance protein MccF
BTL47_RS09975	COG1126	abc transporter atp-binding protein
BTL47_RS09980	COG0765	amino acid transport
BTL47_RS09985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTL47_RS10030	COG2200	EAL domain
BTL47_RS10060	COG1253	flavin adenine dinucleotide binding
BTL47_RS10065	COG2203	Gaf domain
BTL47_RS10065	COG5001	Diguanylate cyclase
BTL47_RS10065	COG3706	GGDEF domain
BTL47_RS10065	COG4251	negative regulation of phosphorylation
BTL47_RS10070	COG2197	response regulator
BTL47_RS10075	COG2205	protein histidine kinase activity
BTL47_RS10075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTL47_RS10100	COG0076	glutamate decarboxylase activity
BTL47_RS10105	COG2985	domain, Protein
BTL47_RS10110	COG3189	MarR family transcriptional regulator
BTL47_RS10120	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BTL47_RS10130	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BTL47_RS10130	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BTL47_RS10140	COG0028	Belongs to the TPP enzyme family
BTL47_RS10150	COG1012	belongs to the aldehyde dehydrogenase family
BTL47_RS10160	COG0688	phosphatidylethanolamine metabolic process
BTL47_RS10165	COG1304	FMN binding
BTL47_RS10170	COG1464	Belongs to the NlpA lipoprotein family
BTL47_RS10190	COG0697	spore germination
BTL47_RS10195	COG2133	pyrroloquinoline quinone binding
BTL47_RS10200	COG0625	glutathione transferase activity
BTL47_RS10215	COG1794	racemase activity, acting on amino acids and derivatives
BTL47_RS10235	COG0559	Belongs to the binding-protein-dependent transport system permease family
BTL47_RS10245	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BTL47_RS10260	COG1175	transmembrane transport
BTL47_RS10265	COG0395	ABC-type sugar transport system, permease component
BTL47_RS10270	COG3842	ATPase activity
BTL47_RS10295	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BTL47_RS10310	COG0438	transferase activity, transferring glycosyl groups
BTL47_RS10335	COG0463	Glycosyl transferase, family 2
BTL47_RS10350	COG0783	Belongs to the Dps family
BTL47_RS10355	COG0583	DNA-binding transcription factor activity
BTL47_RS10360	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BTL47_RS10390	COG1840	ABC-type Fe3 transport system, periplasmic component
BTL47_RS10400	COG3842	ATPase activity
BTL47_RS10405	COG1741	Belongs to the pirin family
BTL47_RS10410	COG1741	Belongs to the pirin family
BTL47_RS10415	COG0583	DNA-binding transcription factor activity
BTL47_RS10430	COG0174	glutamine synthetase
BTL47_RS10435	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BTL47_RS10440	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BTL47_RS10450	COG0840	transmembrane signaling receptor activity
BTL47_RS10465	COG0583	DNA-binding transcription factor activity
BTL47_RS10470	COG1960	acyl-CoA dehydrogenase activity
BTL47_RS10475	COG2079	MmgE PrpD family protein
BTL47_RS10485	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BTL47_RS10490	COG1561	YicC-like family, N-terminal region
BTL47_RS10500	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BTL47_RS10505	COG0791	NLP P60 protein
BTL47_RS10510	COG1028	Short-chain dehydrogenase reductase Sdr
BTL47_RS10515	COG0194	GDP metabolic process
BTL47_RS10520	COG1758	RNA polymerase activity
BTL47_RS10525	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BTL47_RS10530	COG1126	abc transporter atp-binding protein
BTL47_RS10535	COG0765	amino acid transport
BTL47_RS10540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTL47_RS10550	COG2831	hemolysin activation secretion protein
BTL47_RS10560	COG3188	usher protein
BTL47_RS10565	COG3121	Chaperone
BTL47_RS10585	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
BTL47_RS10585	COG3210	domain, Protein
BTL47_RS10585	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
BTL47_RS10585	COG3064	Membrane
BTL47_RS10585	COG3064	Membrane
BTL47_RS10585	COG3210	domain, Protein
BTL47_RS10595	COG4181	ATPase activity
BTL47_RS10605	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BTL47_RS10610	COG0584	glycerophosphoryl diester phosphodiesterase
BTL47_RS10615	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BTL47_RS10625	COG0678	peroxiredoxin activity
BTL47_RS10625	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BTL47_RS10635	COG2217	Heavy metal translocating P-type atpase
BTL47_RS10640	COG0789	Transcriptional regulator
BTL47_RS10645	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BTL47_RS10680	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BTL47_RS10690	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BTL47_RS10715	COG0583	DNA-binding transcription factor activity
BTL47_RS10720	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BTL47_RS10725	COG2252	PERMEase
BTL47_RS10730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BTL47_RS10735	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BTL47_RS10770	COG0488	(ABC) transporter
BTL47_RS10775	COG1619	proteins homologs of microcin C7 resistance protein MccF
BTL47_RS10780	COG0590	tRNA wobble adenosine to inosine editing
BTL47_RS10795	COG1320	monovalent cation:proton antiporter activity
BTL47_RS10800	COG2212	antiporter activity
BTL47_RS10805	COG1863	multisubunit Na H antiporter MnhE subunit
BTL47_RS10810	COG0651	ATP synthesis coupled electron transport
BTL47_RS10815	COG1006	Multisubunit Na H antiporter MnhC subunit
BTL47_RS10820	COG2111	Na H antiporter
BTL47_RS10820	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BTL47_RS10825	COG3181	Tripartite tricarboxylate transporter family receptor
BTL47_RS10850	COG0420	3'-5' exonuclease activity
BTL47_RS10885	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BTL47_RS10895	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BTL47_RS10905	COG2130	NADP-dependent
BTL47_RS10910	COG1309	transcriptional regulator
BTL47_RS10920	COG1131	(ABC) transporter
BTL47_RS10925	COG0842	Transport permease protein
BTL47_RS10935	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BTL47_RS10970	COG0602	queuosine metabolic process
BTL47_RS10975	COG0720	synthase
BTL47_RS11010	COG0587	DNA-directed DNA polymerase activity
BTL47_RS11020	COG0390	transport system, permease component
BTL47_RS11025	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BTL47_RS11030	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
BTL47_RS11085	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BTL47_RS11110	COG5507	3-demethylubiquinone-9 3-methyltransferase
BTL47_RS11145	COG1396	sequence-specific DNA binding
BTL47_RS11165	COG2801	Transposase and inactivated derivatives
BTL47_RS11185	COG0583	DNA-binding transcription factor activity
BTL47_RS11190	COG2814	Major facilitator Superfamily
BTL47_RS11215	COG2807	transmembrane transport
BTL47_RS11220	COG2207	Transcriptional regulator
BTL47_RS11225	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BTL47_RS11230	COG2814	Major facilitator Superfamily
BTL47_RS11245	COG1012	belongs to the aldehyde dehydrogenase family
BTL47_RS11280	COG0583	DNA-binding transcription factor activity
BTL47_RS11300	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BTL47_RS11325	COG0384	phenazine biosynthesis protein PhzF
BTL47_RS11330	COG1733	regulation of RNA biosynthetic process
BTL47_RS11365	COG3177	Filamentation induced by cAMP protein fic
BTL47_RS11375	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BTL47_RS11375	COG0519	Catalyzes the synthesis of GMP from XMP
BTL47_RS11390	COG1695	Transcriptional regulator
BTL47_RS11405	COG2072	flavoprotein involved in K transport
BTL47_RS11410	COG0601	transmembrane transport
BTL47_RS11430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BTL47_RS11440	COG4608	Belongs to the ABC transporter superfamily
BTL47_RS11445	COG0747	negative chemotaxis
BTL47_RS11485	COG0047	phosphoribosylformylglycinamidine synthase activity
BTL47_RS11485	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BTL47_RS11490	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BTL47_RS11510	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BTL47_RS11510	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BTL47_RS11515	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BTL47_RS11525	COG0613	PHP domain protein
BTL47_RS11585	COG1012	belongs to the aldehyde dehydrogenase family
BTL47_RS11595	COG0583	DNA-binding transcription factor activity
BTL47_RS11615	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BTL47_RS11625	COG3181	Tripartite tricarboxylate transporter family receptor
BTL47_RS11635	COG3181	Tripartite tricarboxylate transporter family receptor
BTL47_RS11665	COG1595	DNA-templated transcription, initiation
BTL47_RS11670	COG3712	iron ion homeostasis
BTL47_RS11680	COG0084	hydrolase, TatD family'
BTL47_RS11685	COG1136	(ABC) transporter
BTL47_RS11700	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BTL47_RS11710	COG1028	Short-chain dehydrogenase reductase Sdr
BTL47_RS11715	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BTL47_RS11725	COG1803	Methylglyoxal synthase
BTL47_RS11745	COG2801	Transposase and inactivated derivatives
BTL47_RS11750	COG2801	Transposase and inactivated derivatives
BTL47_RS11775	COG2975	iron-sulfur cluster assembly
BTL47_RS11780	COG0633	Ferredoxin
BTL47_RS11785	COG0443	Heat shock 70 kDa protein
BTL47_RS11790	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BTL47_RS11795	COG0316	Belongs to the HesB IscA family
BTL47_RS11800	COG0822	iron-sulfur transferase activity
BTL47_RS11805	COG1104	cysteine desulfurase activity
BTL47_RS11815	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BTL47_RS11820	COG0556	nucleotide-excision repair
BTL47_RS11835	COG0583	DNA-binding transcription factor activity
BTL47_RS11855	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BTL47_RS11895	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BTL47_RS11910	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BTL47_RS11920	COG0740	serine-type endopeptidase activity
BTL47_RS11925	COG0544	peptidyl-prolyl cis-trans isomerase activity
BTL47_RS11965	COG2801	Transposase and inactivated derivatives
BTL47_RS11975	COG1278	Cold shock
BTL47_RS12005	COG2433	Pfam Transposase IS66
BTL47_RS12065	COG1530	ribonuclease E activity
BTL47_RS12095	COG1846	Transcriptional regulator
BTL47_RS12105	COG1566	PFAM secretion protein HlyD family protein
BTL47_RS12110	COG2814	Major facilitator Superfamily
BTL47_RS12115	COG0473	3-isopropylmalate dehydrogenase activity
BTL47_RS12135	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BTL47_RS12140	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BTL47_RS12145	COG0433	COG0433 Predicted ATPase
BTL47_RS12150	COG0217	transcriptional regulatory protein
BTL47_RS12155	COG0151	Belongs to the GarS family
BTL47_RS12165	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BTL47_RS12170	COG0799	negative regulation of ribosome biogenesis
BTL47_RS12175	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BTL47_RS12180	COG0424	maF-like protein
BTL47_RS12190	COG4191	Histidine kinase
BTL47_RS12195	COG2204	response regulator
BTL47_RS12220	COG0500	methyltransferase
BTL47_RS12235	COG0803	Belongs to the bacterial solute-binding protein 9 family
BTL47_RS12240	COG1121	(ABC) transporter
BTL47_RS12245	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BTL47_RS12250	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BTL47_RS12280	COG4993	Dehydrogenase
BTL47_RS12305	COG2814	Major facilitator Superfamily
BTL47_RS12325	COG0037	tRNA processing
BTL47_RS12330	COG0825	malonyl-CoA metabolic process
BTL47_RS12340	COG0215	cysteine-tRNA ligase activity
BTL47_RS12350	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BTL47_RS12355	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BTL47_RS12360	COG1968	undecaprenyl-diphosphatase activity
BTL47_RS12365	COG1253	flavin adenine dinucleotide binding
BTL47_RS12370	COG0483	inositol monophosphate 1-phosphatase activity
BTL47_RS12390	COG0668	transmembrane transport
BTL47_RS12415	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BTL47_RS12425	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BTL47_RS12440	COG1802	Transcriptional regulator
BTL47_RS12460	COG3360	Dodecin
BTL47_RS12480	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BTL47_RS12485	COG2850	peptidyl-arginine hydroxylation
BTL47_RS12495	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BTL47_RS12500	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BTL47_RS12505	COG1994	Peptidase M50
BTL47_RS12510	COG0009	L-threonylcarbamoyladenylate synthase
BTL47_RS12515	COG2321	neutral zinc metallopeptidase
BTL47_RS12535	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BTL47_RS12545	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BTL47_RS12555	COG2271	Major facilitator Superfamily
BTL47_RS12630	COG2202	Pas domain
BTL47_RS12630	COG2200	EAL domain
BTL47_RS12630	COG2199	diguanylate cyclase activity
BTL47_RS12635	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
BTL47_RS12655	COG1960	acyl-CoA dehydrogenase activity
BTL47_RS12660	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BTL47_RS12665	COG2186	Transcriptional regulator
BTL47_RS12690	COG1595	DNA-templated transcription, initiation
BTL47_RS12725	COG1028	Short-chain dehydrogenase reductase Sdr
BTL47_RS12740	COG0179	Fumarylacetoacetate (FAA) hydrolase
BTL47_RS12760	COG4604	ABC transporter, ATP-binding protein
BTL47_RS12765	COG4605	iron ion homeostasis
BTL47_RS12770	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTL47_RS12775	COG4607	ABC-type enterochelin transport system periplasmic component
BTL47_RS12780	COG0438	transferase activity, transferring glycosyl groups
BTL47_RS12790	COG0149	triose-phosphate isomerase activity
BTL47_RS12795	COG4221	oxidoreductase activity
BTL47_RS12795	COG3321	synthase
BTL47_RS12795	COG0604	alcohol dehydrogenase
BTL47_RS12795	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BTL47_RS12825	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BTL47_RS12825	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BTL47_RS12830	COG0668	transmembrane transport
BTL47_RS12835	COG0165	Argininosuccinate lyase
BTL47_RS12845	COG0789	Transcriptional regulator
BTL47_RS12855	COG0501	Belongs to the peptidase M48B family
BTL47_RS12860	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BTL47_RS12885	COG1024	Enoyl-CoA hydratase
BTL47_RS12890	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BTL47_RS12910	COG3468	outer membrane autotransporter barrel domain protein
BTL47_RS12950	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BTL47_RS12955	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BTL47_RS12960	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BTL47_RS12965	COG1674	ftsk spoiiie
BTL47_RS12970	COG0492	ferredoxin-NADP+ reductase activity
BTL47_RS12975	COG1193	negative regulation of DNA recombination
BTL47_RS12990	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BTL47_RS13005	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BTL47_RS13010	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BTL47_RS13015	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
BTL47_RS13025	COG0745	RESPONSE REGULATOR receiver
BTL47_RS13060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BTL47_RS13080	COG0612	Peptidase, M16
BTL47_RS13090	COG0443	Heat shock 70 kDa protein
BTL47_RS13100	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BTL47_RS13110	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BTL47_RS13115	COG1420	regulation of RNA biosynthetic process
BTL47_RS13120	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BTL47_RS13125	COG0497	DNA recombination
BTL47_RS13155	COG0735	belongs to the Fur family
BTL47_RS13160	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BTL47_RS13205	COG2828	Protein conserved in bacteria
BTL47_RS13210	COG1280	lysine exporter protein (LysE YggA)
BTL47_RS13215	COG3181	Tripartite tricarboxylate transporter family receptor
BTL47_RS13235	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BTL47_RS13240	COG1802	Transcriptional regulator
BTL47_RS13245	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BTL47_RS13250	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BTL47_RS13255	COG1335	isochorismatase
BTL47_RS13260	COG0523	cobalamin synthesis protein
BTL47_RS13290	COG0583	DNA-binding transcription factor activity
BTL47_RS13300	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BTL47_RS13305	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BTL47_RS13310	COG0167	dihydroorotate dehydrogenase activity
BTL47_RS13355	COG4783	chaperone-mediated protein folding
BTL47_RS13360	COG0429	hydrolase of the alpha beta-hydrolase fold
BTL47_RS13385	COG0513	Belongs to the DEAD box helicase family
BTL47_RS13405	COG1414	Transcriptional regulator
BTL47_RS13450	COG0006	proline dipeptidase activity
BTL47_RS13460	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BTL47_RS13485	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BTL47_RS13490	COG0632	four-way junction helicase activity
BTL47_RS13505	COG2255	four-way junction helicase activity
BTL47_RS13510	COG0514	ATP-dependent DNA helicase (RecQ)
BTL47_RS13530	COG1294	oxidase, subunit
BTL47_RS13540	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BTL47_RS13545	COG0850	regulation of cytokinetic process
BTL47_RS13550	COG2894	cell division
BTL47_RS13555	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BTL47_RS13580	COG0488	(ABC) transporter
BTL47_RS13595	COG4608	Belongs to the ABC transporter superfamily
BTL47_RS13600	COG0444	Belongs to the ABC transporter superfamily
BTL47_RS13605	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BTL47_RS13620	COG1215	transferase activity, transferring glycosyl groups
BTL47_RS13625	COG0583	DNA-binding transcription factor activity
BTL47_RS13630	COG1368	sulfuric ester hydrolase activity
BTL47_RS13635	COG1686	Belongs to the peptidase S11 family
BTL47_RS13645	COG1280	lysine exporter protein (LysE YggA)
BTL47_RS13655	COG1064	alcohol dehydrogenase
BTL47_RS13660	COG4191	Histidine kinase
BTL47_RS13665	COG4566	intracellular signal transduction
BTL47_RS13675	COG1802	Transcriptional regulator
BTL47_RS13700	COG3181	Tripartite tricarboxylate transporter family receptor
BTL47_RS13705	COG0513	Belongs to the DEAD box helicase family
BTL47_RS13710	COG0668	transmembrane transport
BTL47_RS13725	COG1595	DNA-templated transcription, initiation
BTL47_RS13765	COG0583	DNA-binding transcription factor activity
BTL47_RS13770	COG0531	amino acid
BTL47_RS13775	COG1982	Orn Lys Arg decarboxylase major
BTL47_RS13800	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BTL47_RS13805	COG0459	protein refolding
BTL47_RS13815	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BTL47_RS13820	COG1252	NADH dehydrogenase
BTL47_RS13825	COG0284	orotidine-5'-phosphate decarboxylase activity
BTL47_RS13835	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BTL47_RS13845	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BTL47_RS13850	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BTL47_RS13880	COG1595	DNA-templated transcription, initiation
BTL47_RS13890	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BTL47_RS13895	COG3639	organic phosphonate transmembrane transporter activity
BTL47_RS13900	COG3639	organic phosphonate transmembrane transporter activity
BTL47_RS13915	COG0742	ribosomal rna small subunit methyltransferase
BTL47_RS13920	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BTL47_RS13925	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BTL47_RS13930	COG3135	benzoate transporter
BTL47_RS13950	COG4774	siderophore transport
BTL47_RS13975	COG1024	Enoyl-CoA hydratase
BTL47_RS13980	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BTL47_RS13985	COG1960	acyl-CoA dehydrogenase activity
BTL47_RS13995	COG0318	PFAM AMP-dependent synthetase and ligase
BTL47_RS14000	COG3181	Tripartite tricarboxylate transporter family receptor
BTL47_RS14010	COG0583	DNA-binding transcription factor activity
BTL47_RS14035	COG0277	FAD linked oxidase domain protein
BTL47_RS14055	COG1802	Transcriptional regulator
BTL47_RS14065	COG2271	Major facilitator Superfamily
BTL47_RS14075	COG0583	DNA-binding transcription factor activity
BTL47_RS14100	COG0012	GTP binding
BTL47_RS14110	COG0193	aminoacyl-tRNA hydrolase activity
BTL47_RS14115	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BTL47_RS14120	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BTL47_RS14130	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BTL47_RS14145	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BTL47_RS14170	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
BTL47_RS14180	COG1368	sulfuric ester hydrolase activity
BTL47_RS14185	COG2186	Transcriptional regulator
BTL47_RS14195	COG3181	Tripartite tricarboxylate transporter family receptor
BTL47_RS14210	COG0277	FAD linked oxidase domain protein
BTL47_RS14225	COG0166	Belongs to the GPI family
BTL47_RS14230	COG0438	transferase activity, transferring glycosyl groups
BTL47_RS14235	COG0438	transferase activity, transferring glycosyl groups
BTL47_RS14250	COG0438	transferase activity, transferring glycosyl groups
BTL47_RS14265	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BTL47_RS14270	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BTL47_RS14275	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
BTL47_RS14285	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BTL47_RS14295	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTL47_RS14300	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BTL47_RS14315	COG0747	negative chemotaxis
BTL47_RS14325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BTL47_RS14330	COG4172	Belongs to the ABC transporter superfamily
BTL47_RS14350	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BTL47_RS14350	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BTL47_RS14355	COG0509	glycine decarboxylation via glycine cleavage system
BTL47_RS14360	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BTL47_RS14365	COG2081	HI0933 family
BTL47_RS14380	COG0456	acetyltransferase
BTL47_RS14385	COG0717	Belongs to the dCTP deaminase family
BTL47_RS14400	COG0489	protein tyrosine kinase activity
BTL47_RS14410	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BTL47_RS14410	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BTL47_RS14435	COG3539	Fimbrial protein
BTL47_RS14450	COG0745	RESPONSE REGULATOR receiver
BTL47_RS14475	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
BTL47_RS14490	COG2084	Dehydrogenase
BTL47_RS14495	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BTL47_RS14520	COG3842	ATPase activity
BTL47_RS14525	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BTL47_RS14530	COG1960	acyl-CoA dehydrogenase activity
BTL47_RS14540	COG0583	DNA-binding transcription factor activity
BTL47_RS14550	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BTL47_RS14555	COG1024	Enoyl-CoA hydratase
BTL47_RS14570	COG0583	DNA-binding transcription factor activity
BTL47_RS14575	COG1408	metallophosphoesterase
BTL47_RS14580	COG0625	glutathione transferase activity
BTL47_RS14615	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BTL47_RS14615	COG0426	domain, Protein
BTL47_RS14620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BTL47_RS14625	COG0583	DNA-binding transcription factor activity
BTL47_RS14635	COG1024	Enoyl-CoA hydratase
BTL47_RS14645	COG1960	acyl-CoA dehydrogenase activity
BTL47_RS14650	COG1028	Short-chain dehydrogenase reductase Sdr
BTL47_RS14655	COG1028	Short-chain dehydrogenase reductase Sdr
BTL47_RS14675	COG3181	Tripartite tricarboxylate transporter family receptor
BTL47_RS14680	COG1028	Short-chain dehydrogenase reductase Sdr
BTL47_RS14690	COG3181	Tripartite tricarboxylate transporter family receptor
BTL47_RS14730	COG0583	DNA-binding transcription factor activity
BTL47_RS14735	COG1960	acyl-CoA dehydrogenase activity
BTL47_RS14740	COG3181	Tripartite tricarboxylate transporter family receptor
BTL47_RS14745	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BTL47_RS14750	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BTL47_RS14775	COG0560	Phosphoserine phosphatase
BTL47_RS14780	COG0583	DNA-binding transcription factor activity
BTL47_RS14795	COG3842	ATPase activity
BTL47_RS14810	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BTL47_RS14830	COG0625	glutathione transferase activity
BTL47_RS14875	COG4336	lyase activity
BTL47_RS14885	COG0326	Molecular chaperone. Has ATPase activity
BTL47_RS14890	COG2233	PERMEase
BTL47_RS14930	COG2818	Glycosylase
BTL47_RS14935	COG0727	PFAM Uncharacterised protein family (UPF0153)
BTL47_RS14960	COG0402	S-adenosylhomocysteine deaminase activity
BTL47_RS14970	COG0156	8-amino-7-oxononanoate synthase activity
BTL47_RS14975	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BTL47_RS15025	COG1464	Belongs to the NlpA lipoprotein family
BTL47_RS15030	COG2011	ABC-type metal ion transport system permease component
BTL47_RS15035	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BTL47_RS15040	COG1501	Belongs to the glycosyl hydrolase 31 family
BTL47_RS15045	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BTL47_RS15045	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
BTL47_RS15050	COG0483	inositol monophosphate 1-phosphatase activity
BTL47_RS15055	COG0318	PFAM AMP-dependent synthetase and ligase
BTL47_RS15060	COG1473	amidohydrolase
BTL47_RS15065	COG0583	DNA-binding transcription factor activity
BTL47_RS15070	COG2855	membrane
BTL47_RS15080	COG2239	Acts as a magnesium transporter
BTL47_RS15095	COG1522	sequence-specific DNA binding
BTL47_RS15135	COG0330	HflC and HflK could
BTL47_RS15140	COG0330	HflC and HflK could
BTL47_RS15145	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BTL47_RS15150	COG1923	regulation of RNA biosynthetic process
BTL47_RS15160	COG1160	GTP binding
BTL47_RS15165	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BTL47_RS15170	COG2976	Protein conserved in bacteria
BTL47_RS15175	COG0124	histidyl-tRNA synthetase
BTL47_RS15190	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BTL47_RS15195	COG0105	UTP biosynthetic process
BTL47_RS15200	COG0525	valine-tRNA ligase activity
BTL47_RS15210	COG0336	Belongs to the RNA methyltransferase TrmD family
BTL47_RS15215	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BTL47_RS15220	COG0228	four-way junction DNA binding
BTL47_RS15225	COG0425	Belongs to the sulfur carrier protein TusA family
BTL47_RS15230	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BTL47_RS15295	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BTL47_RS15300	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BTL47_RS15300	COG0543	2 iron, 2 sulfur cluster binding
BTL47_RS15305	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BTL47_RS15310	COG2076	Multidrug Resistance protein
BTL47_RS15315	COG3217	Mosc domain protein beta barrel domain protein
BTL47_RS15315	COG0633	Ferredoxin
BTL47_RS15320	COG5285	phytanoyl-CoA dioxygenase
BTL47_RS15325	COG0662	Cupin 2, conserved barrel domain protein
BTL47_RS15335	COG0456	acetyltransferase
BTL47_RS15355	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BTL47_RS15385	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BTL47_RS15410	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BTL47_RS15415	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BTL47_RS15420	COG1760	l-serine dehydratase
BTL47_RS15425	COG1283	sodium-dependent phosphate transmembrane transporter activity
BTL47_RS15430	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BTL47_RS15435	COG0412	Dienelactone hydrolase
BTL47_RS15440	COG0428	transporter
BTL47_RS15450	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BTL47_RS15455	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BTL47_RS15460	COG1845	cytochrome c oxidase, subunit III
BTL47_RS15465	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BTL47_RS15475	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BTL47_RS15475	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BTL47_RS15500	COG1942	4-Oxalocrotonate Tautomerase
BTL47_RS15510	COG4176	ABC-type proline glycine betaine transport system permease component
BTL47_RS15530	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BTL47_RS15535	COG2814	Major facilitator Superfamily
BTL47_RS15540	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BTL47_RS15545	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BTL47_RS15570	COG1846	Transcriptional regulator
BTL47_RS15575	COG2814	Major facilitator Superfamily
BTL47_RS15580	COG0495	leucyl-tRNA aminoacylation
BTL47_RS15595	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BTL47_RS15615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BTL47_RS15620	COG2274	protein secretion by the type I secretion system
BTL47_RS15665	COG0427	acetyl-CoA hydrolase
BTL47_RS15675	COG3264	Mechanosensitive ion channel
BTL47_RS15675	COG1511	domain protein
BTL47_RS15680	COG0730	response to heat
BTL47_RS15695	COG2176	DNA-directed DNA polymerase activity
BTL47_RS15715	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BTL47_RS15720	COG3384	dioxygenase
BTL47_RS15735	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BTL47_RS15805	COG4964	Belongs to the GSP D family
BTL47_RS15850	COG1846	Transcriptional regulator
BTL47_RS15885	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BTL47_RS15895	COG2070	2-Nitropropane dioxygenase
BTL47_RS15900	COG2070	2-Nitropropane dioxygenase
BTL47_RS15910	COG2610	gluconate transmembrane transporter activity
BTL47_RS15925	COG1408	metallophosphoesterase
BTL47_RS15930	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BTL47_RS15930	COG0493	'glutamate synthase
BTL47_RS15935	COG2199	diguanylate cyclase activity
BTL47_RS15940	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BTL47_RS15975	COG2159	amidohydrolase
BTL47_RS16010	COG1024	Enoyl-CoA hydratase
BTL47_RS16015	COG2186	Transcriptional regulator
BTL47_RS16020	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BTL47_RS16030	COG0833	amino acid
BTL47_RS16040	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BTL47_RS16075	COG5265	(ABC) transporter
BTL47_RS16115	COG1971	Probably functions as a manganese efflux pump
BTL47_RS16120	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BTL47_RS16130	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BTL47_RS16135	COG2814	Major facilitator Superfamily
BTL47_RS16165	COG0747	negative chemotaxis
BTL47_RS16175	COG0625	glutathione transferase activity
BTL47_RS16205	COG1595	DNA-templated transcription, initiation
BTL47_RS16215	COG4774	siderophore transport
BTL47_RS16230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BTL47_RS16245	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BTL47_RS16250	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
BTL47_RS16275	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BTL47_RS16280	COG1024	Enoyl-CoA hydratase
BTL47_RS16315	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BTL47_RS16320	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BTL47_RS16325	COG1116	anion transmembrane transporter activity
BTL47_RS16335	COG3585	molybdate ion transport
BTL47_RS16395	COG0583	DNA-binding transcription factor activity
BTL47_RS16400	COG4948	Mandelate Racemase Muconate Lactonizing
BTL47_RS16405	COG3181	Tripartite tricarboxylate transporter family receptor
BTL47_RS16430	COG3181	Tripartite tricarboxylate transporter family receptor
BTL47_RS16435	COG3181	Tripartite tricarboxylate transporter family receptor
BTL47_RS16470	COG4177	L-phenylalanine transmembrane transporter activity
BTL47_RS16495	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BTL47_RS16510	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BTL47_RS16515	COG1538	Outer membrane efflux protein
BTL47_RS16520	COG0577	efflux transmembrane transporter activity
BTL47_RS16520	COG1136	(ABC) transporter
BTL47_RS16525	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BTL47_RS16540	COG0259	pyridoxamine-phosphate oxidase activity
BTL47_RS16545	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BTL47_RS16550	COG0579	oxidoreductase
BTL47_RS16560	COG0405	Gamma-glutamyltransferase
BTL47_RS16570	COG3181	Tripartite tricarboxylate transporter family receptor
BTL47_RS16580	COG0114	fumarate hydratase activity
BTL47_RS16585	COG0802	atpase or kinase
BTL47_RS16590	COG0860	N-Acetylmuramoyl-L-alanine amidase
BTL47_RS16595	COG0586	Pfam SNARE associated Golgi protein
BTL47_RS16600	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BTL47_RS16605	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BTL47_RS16610	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BTL47_RS16625	COG0617	tRNA 3'-terminal CCA addition
BTL47_RS16660	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
BTL47_RS16670	COG1024	Enoyl-CoA hydratase
BTL47_RS16680	COG2188	Transcriptional regulator
BTL47_RS16685	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BTL47_RS16700	COG0752	glycyl-tRNA synthetase alpha subunit
BTL47_RS16705	COG0751	glycine-tRNA ligase activity
BTL47_RS16710	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BTL47_RS16715	COG0204	Acyl-transferase
BTL47_RS16745	COG0242	peptide deformylase activity
BTL47_RS16755	COG0700	Nucleoside recognition
BTL47_RS16760	COG0469	pyruvate kinase activity
BTL47_RS16765	COG1929	Belongs to the glycerate kinase type-1 family
BTL47_RS16775	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BTL47_RS16780	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BTL47_RS16785	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BTL47_RS16795	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BTL47_RS16805	COG2154	pterin-4-alpha-carbinolamine dehydratase
BTL47_RS16810	COG2885	chlorophyll binding
BTL47_RS16820	COG0667	Aldo Keto reductase
BTL47_RS16830	COG3181	Tripartite tricarboxylate transporter family receptor
BTL47_RS16850	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BTL47_RS16855	COG0288	reversible hydration of carbon dioxide
BTL47_RS16875	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BTL47_RS16885	COG4829	muconolactone delta-isomerase
BTL47_RS16890	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BTL47_RS16900	COG1414	Transcriptional regulator
BTL47_RS16905	COG1028	Short-chain dehydrogenase reductase Sdr
BTL47_RS16910	COG2031	fatty acid transporter
BTL47_RS16915	COG1250	3-hydroxyacyl-CoA dehydrogenase
BTL47_RS16925	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BTL47_RS16930	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BTL47_RS16945	COG0129	dihydroxy-acid dehydratase activity
BTL47_RS16950	COG1609	Transcriptional regulator
BTL47_RS16970	COG4106	trans-aconitate 2-methyltransferase activity
BTL47_RS16990	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BTL47_RS17030	COG0163	prenyltransferase activity
BTL47_RS17035	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BTL47_RS17040	COG2890	protein-(glutamine-N5) methyltransferase activity
BTL47_RS17045	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BTL47_RS17050	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BTL47_RS17065	COG3712	iron ion homeostasis
BTL47_RS17095	COG0659	secondary active sulfate transmembrane transporter activity
BTL47_RS17115	COG1028	Short-chain dehydrogenase reductase Sdr
BTL47_RS17130	COG4774	siderophore transport
BTL47_RS17140	COG1595	DNA-templated transcription, initiation
BTL47_RS17155	COG0142	geranyltranstransferase activity
BTL47_RS17160	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BTL47_RS17165	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BTL47_RS17170	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BTL47_RS17175	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BTL47_RS17195	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BTL47_RS17195	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BTL47_RS17200	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BTL47_RS17215	COG0583	DNA-binding transcription factor activity
BTL47_RS17220	COG0861	Integral membrane protein TerC family
BTL47_RS17235	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BTL47_RS17240	COG0793	Belongs to the peptidase S41A family
BTL47_RS17245	COG4942	peptidase
BTL47_RS17250	COG0588	phosphoglycerate mutase activity
BTL47_RS17260	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BTL47_RS17265	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BTL47_RS17270	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BTL47_RS17275	COG3181	Tripartite tricarboxylate transporter family receptor
BTL47_RS17290	COG2226	methyltransferase
BTL47_RS17295	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
BTL47_RS17300	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BTL47_RS17310	COG2204	response regulator
BTL47_RS17315	COG5000	phosphorelay sensor kinase activity
BTL47_RS17325	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BTL47_RS17325	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BTL47_RS17365	COG2188	Transcriptional regulator
BTL47_RS17380	COG0583	DNA-binding transcription factor activity
BTL47_RS17385	COG1012	belongs to the aldehyde dehydrogenase family
BTL47_RS17405	COG0546	phosphoglycolate phosphatase activity
BTL47_RS17420	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BTL47_RS17425	COG0242	peptide deformylase activity
BTL47_RS17435	COG1522	sequence-specific DNA binding
BTL47_RS17440	COG2879	small protein
BTL47_RS17445	COG1966	Carbon starvation protein
BTL47_RS17475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTL47_RS17480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTL47_RS17485	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BTL47_RS17490	COG3181	Tripartite tricarboxylate transporter family receptor
BTL47_RS17555	COG1172	Belongs to the binding-protein-dependent transport system permease family
BTL47_RS17590	COG0640	Transcriptional regulator
BTL47_RS17630	COG0735	belongs to the Fur family
BTL47_RS17635	COG2207	Transcriptional regulator
BTL47_RS17640	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BTL47_RS17645	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BTL47_RS17650	COG0513	Belongs to the DEAD box helicase family
BTL47_RS17680	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BTL47_RS17695	COG1305	Transglutaminase-like
BTL47_RS17735	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BTL47_RS17740	COG1950	PFAM Membrane protein of
BTL47_RS17765	COG0024	Methionine aminopeptidase
BTL47_RS17770	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BTL47_RS17780	COG1560	Kdo2-lipid A biosynthetic process
BTL47_RS17785	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BTL47_RS17795	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BTL47_RS17830	COG0735	belongs to the Fur family
BTL47_RS17835	COG0523	cobalamin synthesis protein
BTL47_RS17850	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BTL47_RS17860	COG2096	Adenosyltransferase
BTL47_RS17865	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BTL47_RS17870	COG0321	lipoyl(octanoyl) transferase activity
BTL47_RS17880	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BTL47_RS17885	COG1686	Belongs to the peptidase S11 family
BTL47_RS17910	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BTL47_RS17920	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BTL47_RS17930	COG0859	PFAM glycosyl transferase family 9
BTL47_RS17965	COG0477	Major facilitator Superfamily
BTL47_RS17980	COG3568	Endonuclease Exonuclease Phosphatase
BTL47_RS17985	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BTL47_RS18015	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BTL47_RS18020	COG1956	GAF domain-containing protein
BTL47_RS18025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTL47_RS18040	COG2186	Transcriptional regulator
BTL47_RS18045	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BTL47_RS18060	COG1840	ABC-type Fe3 transport system, periplasmic component
BTL47_RS18100	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BTL47_RS18105	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BTL47_RS18110	COG1086	Polysaccharide biosynthesis protein
BTL47_RS18145	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BTL47_RS18155	COG1028	Short-chain dehydrogenase reductase Sdr
BTL47_RS18160	COG1012	belongs to the aldehyde dehydrogenase family
BTL47_RS18175	COG1522	sequence-specific DNA binding
BTL47_RS18180	COG3781	membrane
BTL47_RS18220	COG2200	EAL domain
BTL47_RS18230	COG0592	DNA-directed DNA polymerase activity
BTL47_RS18235	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BTL47_RS18240	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BTL47_RS18245	COG0594	ribonuclease P activity
BTL47_RS18250	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BTL47_RS18255	COG0706	membrane insertase activity
BTL47_RS18260	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
BTL47_RS18265	COG1473	amidohydrolase
BTL47_RS18270	COG4608	Belongs to the ABC transporter superfamily
BTL47_RS18275	COG0444	Belongs to the ABC transporter superfamily
BTL47_RS18280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BTL47_RS18285	COG0601	transmembrane transport
BTL47_RS18295	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BTL47_RS18310	COG1505	serine-type exopeptidase activity
BTL47_RS18320	COG0281	malic enzyme
BTL47_RS18320	COG0280	phosphate acetyltransferase
BTL47_RS18350	COG0436	Aminotransferase
BTL47_RS18355	COG1278	Cold shock