locus-tag	class	description
FYA58_RS00005	COG0445	tRNA wobble uridine modification
FYA58_RS00010	COG0357	Ribosomal RNA small subunit methyltransferase G
FYA58_RS00015	COG1192	Involved in chromosome partitioning
FYA58_RS00020	COG1475	DNA binding
FYA58_RS00025	COG0252	asparaginase activity
FYA58_RS00045	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FYA58_RS00055	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FYA58_RS00065	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FYA58_RS00070	COG0081	regulation of translation
FYA58_RS00075	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FYA58_RS00080	COG0222	ribosome binding
FYA58_RS00085	COG0085	RNA polymerase activity
FYA58_RS00090	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FYA58_RS00125	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FYA58_RS00130	COG0049	tRNA binding
FYA58_RS00135	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FYA58_RS00140	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FYA58_RS00145	COG0051	transcription antitermination factor activity, RNA binding
FYA58_RS00150	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FYA58_RS00155	COG0088	Forms part of the polypeptide exit tunnel
FYA58_RS00160	COG0089	rRNA binding
FYA58_RS00165	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FYA58_RS00170	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FYA58_RS00175	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FYA58_RS00180	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FYA58_RS00185	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FYA58_RS00190	COG0255	Belongs to the universal ribosomal protein uL29 family
FYA58_RS00195	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FYA58_RS00205	COG4177	L-phenylalanine transmembrane transporter activity
FYA58_RS00215	COG1129	ABC transporter
FYA58_RS00220	COG0411	ABC transporter
FYA58_RS00250	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FYA58_RS00255	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FYA58_RS00260	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FYA58_RS00265	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FYA58_RS00270	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FYA58_RS00275	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FYA58_RS00280	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FYA58_RS00285	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FYA58_RS00290	COG1841	ribosomal large subunit assembly
FYA58_RS00295	COG0200	Binds to the 23S rRNA
FYA58_RS00300	COG0201	protein transport
FYA58_RS00305	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FYA58_RS00310	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FYA58_RS00315	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FYA58_RS00320	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FYA58_RS00325	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FYA58_RS00330	COG0202	RNA polymerase activity
FYA58_RS00335	COG0203	ribosomal protein L17
FYA58_RS00340	COG0537	adenosine 5'-monophosphoramidase activity
FYA58_RS00345	COG1324	tolerance protein
FYA58_RS00350	COG4232	protein-disulfide reductase activity
FYA58_RS00365	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FYA58_RS00375	COG1333	cytochrome c biogenesis protein
FYA58_RS00380	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FYA58_RS00395	COG1965	Belongs to the frataxin family
FYA58_RS00405	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FYA58_RS00410	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FYA58_RS00415	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FYA58_RS00435	COG2814	Major facilitator Superfamily
FYA58_RS00460	COG2801	Transposase and inactivated derivatives
FYA58_RS00490	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FYA58_RS00495	COG2922	Belongs to the Smg family
FYA58_RS00500	COG1629	transport
FYA58_RS00510	COG2358	TRAP transporter, solute receptor (TAXI family
FYA58_RS00520	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FYA58_RS00535	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FYA58_RS00540	COG0183	Belongs to the thiolase family
FYA58_RS00545	COG1960	acyl-CoA dehydrogenase activity
FYA58_RS00570	COG2200	EAL domain
FYA58_RS00575	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FYA58_RS00585	COG0018	arginyl-trna synthetase
FYA58_RS00600	COG0154	amidase activity
FYA58_RS00605	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FYA58_RS00615	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FYA58_RS00625	COG0697	spore germination
FYA58_RS00685	COG3350	monooxygenase activity
FYA58_RS00710	COG1309	transcriptional regulator
FYA58_RS00740	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FYA58_RS00745	COG1280	lysine exporter protein (LysE YggA)
FYA58_RS00750	COG0513	Belongs to the DEAD box helicase family
FYA58_RS00760	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
FYA58_RS00765	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FYA58_RS00795	COG2969	positive regulation of protein catabolic process
FYA58_RS00800	COG0625	glutathione transferase activity
FYA58_RS00805	COG2857	Cytochrome c1
FYA58_RS00810	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FYA58_RS00815	COG0723	plastoquinol--plastocyanin reductase activity
FYA58_RS00820	COG1970	mechanosensitive ion channel activity
FYA58_RS00825	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FYA58_RS00830	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FYA58_RS00840	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FYA58_RS00845	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FYA58_RS00855	COG0140	phosphoribosyl-ATP diphosphatase activity
FYA58_RS00860	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FYA58_RS00865	COG0107	imidazoleglycerol-phosphate synthase activity
FYA58_RS00870	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FYA58_RS00880	COG0131	Imidazoleglycerol-phosphate dehydratase
FYA58_RS00885	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FYA58_RS00890	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FYA58_RS00895	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FYA58_RS00900	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FYA58_RS00910	COG0842	Transport permease protein
FYA58_RS00915	COG1131	(ABC) transporter
FYA58_RS00930	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FYA58_RS00935	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FYA58_RS00940	COG1127	ABC transporter
FYA58_RS00960	COG0070	glutamate synthase
FYA58_RS00960	COG0067	glutamate synthase
FYA58_RS00960	COG0069	glutamate synthase activity
FYA58_RS00985	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FYA58_RS01005	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FYA58_RS01010	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FYA58_RS01055	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FYA58_RS01090	COG0109	protoheme IX farnesyltransferase activity
FYA58_RS01095	COG1999	signal sequence binding
FYA58_RS01115	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FYA58_RS01120	COG2814	Major facilitator Superfamily
FYA58_RS01135	COG1522	sequence-specific DNA binding
FYA58_RS01200	COG4948	Mandelate Racemase Muconate Lactonizing
FYA58_RS01215	COG3119	arylsulfatase activity
FYA58_RS01250	COG0402	S-adenosylhomocysteine deaminase activity
FYA58_RS01260	COG1304	FMN binding
FYA58_RS01265	COG1254	Belongs to the acylphosphatase family
FYA58_RS01275	COG3181	Tripartite tricarboxylate transporter family receptor
FYA58_RS01285	COG1414	Transcriptional regulator
FYA58_RS01305	COG0028	Belongs to the TPP enzyme family
FYA58_RS01310	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FYA58_RS01315	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYA58_RS01320	COG1960	acyl-CoA dehydrogenase activity
FYA58_RS01355	COG3181	Tripartite tricarboxylate transporter family receptor
FYA58_RS01360	COG0583	DNA-binding transcription factor activity
FYA58_RS01375	COG0129	dihydroxy-acid dehydratase activity
FYA58_RS01380	COG2084	Dehydrogenase
FYA58_RS01395	COG1671	Belongs to the UPF0178 family
FYA58_RS01400	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FYA58_RS01410	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FYA58_RS01415	COG0443	Heat shock 70 kDa protein
FYA58_RS01440	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FYA58_RS01440	COG2169	Transcriptional regulator
FYA58_RS01455	COG1683	Conserved Protein
FYA58_RS01460	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FYA58_RS01475	COG1120	ATPase activity
FYA58_RS01480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FYA58_RS01485	COG4558	Periplasmic binding protein
FYA58_RS01490	COG3720	iron ion transport
FYA58_RS01500	COG3712	iron ion homeostasis
FYA58_RS01505	COG1595	DNA-templated transcription, initiation
FYA58_RS01525	COG1607	acyl-coa hydrolase
FYA58_RS01540	COG0437	4 iron, 4 sulfur cluster binding
FYA58_RS01545	COG2864	formate dehydrogenase
FYA58_RS01560	COG3276	selenocysteine insertion sequence binding
FYA58_RS01595	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FYA58_RS01600	COG0512	Glutamine amidotransferase of anthranilate synthase
FYA58_RS01610	COG0546	phosphoglycolate phosphatase activity
FYA58_RS01615	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FYA58_RS01620	COG2967	ApaG domain
FYA58_RS01625	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FYA58_RS01630	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FYA58_RS01635	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FYA58_RS01640	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FYA58_RS01645	COG0037	tRNA processing
FYA58_RS01665	COG1024	Enoyl-CoA hydratase
FYA58_RS01680	COG0356	it plays a direct role in the translocation of protons across the membrane
FYA58_RS01690	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FYA58_RS01695	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FYA58_RS01700	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FYA58_RS01705	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FYA58_RS01710	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FYA58_RS01715	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FYA58_RS01730	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FYA58_RS01735	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FYA58_RS01740	COG0210	DNA helicase
FYA58_RS01755	COG4608	Belongs to the ABC transporter superfamily
FYA58_RS01760	COG0444	Belongs to the ABC transporter superfamily
FYA58_RS01765	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FYA58_RS01790	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FYA58_RS01795	COG1024	Enoyl-CoA hydratase
FYA58_RS01800	COG1024	Enoyl-CoA hydratase
FYA58_RS01805	COG2070	2-Nitropropane dioxygenase
FYA58_RS01820	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYA58_RS01825	COG1250	3-hydroxyacyl-CoA dehydrogenase
FYA58_RS01845	COG2267	carboxylic ester hydrolase activity
FYA58_RS01865	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FYA58_RS01875	COG2813	Specifically methylates the guanine in position
FYA58_RS01875	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FYA58_RS01880	COG2223	nitrite transmembrane transporter activity
FYA58_RS01885	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FYA58_RS01900	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FYA58_RS01905	COG0708	Exodeoxyribonuclease III
FYA58_RS01910	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FYA58_RS01915	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FYA58_RS01920	COG0154	amidase activity
FYA58_RS01925	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FYA58_RS01930	COG1077	Cell shape determining protein MreB Mrl
FYA58_RS01935	COG1792	Involved in formation and maintenance of cell shape
FYA58_RS01945	COG0768	penicillin binding
FYA58_RS01950	COG0772	Belongs to the SEDS family
FYA58_RS01955	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FYA58_RS01960	COG0471	metal ion transport
FYA58_RS01965	COG1309	transcriptional regulator
FYA58_RS01975	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FYA58_RS01990	COG2823	Periplasmic or secreted lipoprotein
FYA58_RS01995	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FYA58_RS02000	COG0792	nuclease activity
FYA58_RS02020	COG1660	Displays ATPase and GTPase activities
FYA58_RS02035	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FYA58_RS02045	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FYA58_RS02055	COG3181	Tripartite tricarboxylate transporter family receptor
FYA58_RS02060	COG1473	amidohydrolase
FYA58_RS02065	COG1137	ATPase activity
FYA58_RS02080	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FYA58_RS02090	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FYA58_RS02110	COG1294	oxidase, subunit
FYA58_RS02120	COG4988	ABC transporter
FYA58_RS02125	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FYA58_RS02130	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FYA58_RS02145	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FYA58_RS02150	COG1238	metal cluster binding
FYA58_RS02160	COG1802	Transcriptional regulator
FYA58_RS02170	COG1984	allophanate hydrolase subunit 2
FYA58_RS02175	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FYA58_RS02185	COG0583	DNA-binding transcription factor activity
FYA58_RS02190	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FYA58_RS02195	COG5002	protein histidine kinase activity
FYA58_RS02200	COG0745	RESPONSE REGULATOR receiver
FYA58_RS02205	COG2226	methyltransferase
FYA58_RS02250	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FYA58_RS02260	COG1028	Short-chain dehydrogenase reductase Sdr
FYA58_RS02280	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FYA58_RS02285	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FYA58_RS02295	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FYA58_RS02315	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FYA58_RS02320	COG1538	Outer membrane efflux protein
FYA58_RS02330	COG0351	phosphomethylpyrimidine kinase
FYA58_RS02335	COG2022	thiamine diphosphate biosynthetic process
FYA58_RS02340	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FYA58_RS02360	COG2226	methyltransferase
FYA58_RS02370	COG1194	a g-specific adenine glycosylase
FYA58_RS02380	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FYA58_RS02385	COG2177	Part of the ABC transporter FtsEX involved in
FYA58_RS02390	COG2884	Cell division ATP-binding protein ftsE
FYA58_RS02395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYA58_RS02400	COG4597	amino acid ABC transporter
FYA58_RS02405	COG0765	amino acid transport
FYA58_RS02410	COG1126	abc transporter atp-binding protein
FYA58_RS02440	COG0477	Major facilitator Superfamily
FYA58_RS02450	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FYA58_RS02455	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FYA58_RS02470	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FYA58_RS02475	COG0237	dephospho-CoA kinase activity
FYA58_RS02480	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
FYA58_RS02490	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FYA58_RS02505	COG3539	Fimbrial protein
FYA58_RS02510	COG3539	Fimbrial protein
FYA58_RS02525	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FYA58_RS02535	COG1846	Transcriptional regulator
FYA58_RS02600	COG1028	Short-chain dehydrogenase reductase Sdr
FYA58_RS02605	COG1024	Enoyl-CoA hydratase
FYA58_RS02610	COG1960	acyl-CoA dehydrogenase activity
FYA58_RS02640	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FYA58_RS02645	COG0352	thiamine-phosphate diphosphorylase activity
FYA58_RS02650	COG0351	phosphomethylpyrimidine kinase
FYA58_RS02660	COG1678	Uncharacterized ACR, COG1678
FYA58_RS02665	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FYA58_RS02690	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FYA58_RS02700	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FYA58_RS02705	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FYA58_RS02715	COG0557	exoribonuclease II activity
FYA58_RS02725	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FYA58_RS02730	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FYA58_RS02735	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FYA58_RS02745	COG0439	Biotin carboxylase
FYA58_RS02750	COG2264	protein methyltransferase activity
FYA58_RS02760	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FYA58_RS02785	COG1696	Membrane protein involved in D-alanine export
FYA58_RS02790	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FYA58_RS02835	COG1522	sequence-specific DNA binding
FYA58_RS02850	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FYA58_RS02915	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FYA58_RS02940	COG3028	Belongs to the UPF0307 family
FYA58_RS02945	COG0312	modulator of DNA gyrase
FYA58_RS02950	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FYA58_RS02955	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FYA58_RS02960	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FYA58_RS02970	COG0316	Belongs to the HesB IscA family
FYA58_RS02980	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FYA58_RS02990	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FYA58_RS02995	COG1881	PFAM PEBP family protein
FYA58_RS03000	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FYA58_RS03005	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FYA58_RS03020	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FYA58_RS03020	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FYA58_RS03035	COG2718	Belongs to the UPF0229 family
FYA58_RS03040	COG2719	SpoVR family
FYA58_RS03100	COG0165	Argininosuccinate lyase
FYA58_RS03105	COG0589	response to stress
FYA58_RS03115	COG2816	NAD+ diphosphatase activity
FYA58_RS03120	COG4993	Dehydrogenase
FYA58_RS03145	COG3181	Tripartite tricarboxylate transporter family receptor
FYA58_RS03150	COG2979	Protein of unknown function (DUF533)
FYA58_RS03155	COG4206	TonB-dependent receptor
FYA58_RS03170	COG0741	lytic transglycosylase activity
FYA58_RS03170	COG1388	LysM domain
FYA58_RS03175	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FYA58_RS03180	COG2226	methyltransferase
FYA58_RS03185	COG0328	RNA-DNA hybrid ribonuclease activity
FYA58_RS03210	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FYA58_RS03230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYA58_RS03235	COG1129	ABC transporter
FYA58_RS03235	COG0842	Transport permease protein
FYA58_RS03240	COG0842	Transport permease protein
FYA58_RS03260	COG0463	Glycosyl transferase, family 2
FYA58_RS03265	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FYA58_RS03280	COG1073	alpha beta
FYA58_RS03290	COG0697	spore germination
FYA58_RS03295	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FYA58_RS03320	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FYA58_RS03350	COG0823	Involved in the tonB-independent uptake of proteins
FYA58_RS03360	COG0848	biopolymer transport protein
FYA58_RS03365	COG0811	peptide transport
FYA58_RS03370	COG0824	Thioesterase
FYA58_RS03375	COG0442	prolyl-tRNA aminoacylation
FYA58_RS03420	COG2084	Dehydrogenase
FYA58_RS03465	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FYA58_RS03470	COG4654	Cytochrome c, class I
FYA58_RS03475	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FYA58_RS03540	COG1473	amidohydrolase
FYA58_RS03545	COG0418	dihydroorotase activity
FYA58_RS03550	COG0488	(ABC) transporter
FYA58_RS03560	COG2001	Belongs to the MraZ family
FYA58_RS03565	COG0275	rRNA processing
FYA58_RS03570	COG3116	cell division
FYA58_RS03580	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FYA58_RS03585	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FYA58_RS03590	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FYA58_RS03600	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FYA58_RS03605	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FYA58_RS03610	COG1181	Belongs to the D-alanine--D-alanine ligase family
FYA58_RS03615	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FYA58_RS03630	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FYA58_RS03645	COG0739	heme binding
FYA58_RS03650	COG0653	protein targeting
FYA58_RS03675	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FYA58_RS03680	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FYA58_RS03690	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FYA58_RS03740	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FYA58_RS03755	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
FYA58_RS03780	COG0583	DNA-binding transcription factor activity
FYA58_RS03790	COG3181	Tripartite tricarboxylate transporter family receptor
FYA58_RS03795	COG2084	Dehydrogenase
FYA58_RS03805	COG1597	lipid kinase activity
FYA58_RS03805	COG1803	Methylglyoxal synthase
FYA58_RS03815	COG0671	phosphoesterase, PA-phosphatase related
FYA58_RS03835	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FYA58_RS03840	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FYA58_RS03845	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FYA58_RS03850	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FYA58_RS03855	COG0649	NAD binding
FYA58_RS03860	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FYA58_RS03870	COG1034	ATP synthesis coupled electron transport
FYA58_RS03875	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FYA58_RS03880	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FYA58_RS03890	COG0713	ATP synthesis coupled electron transport
FYA58_RS03905	COG1007	ATP synthesis coupled electron transport
FYA58_RS03915	COG0560	Phosphoserine phosphatase
FYA58_RS03920	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FYA58_RS03925	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FYA58_RS03930	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FYA58_RS03945	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FYA58_RS03950	COG0450	alkyl hydroperoxide reductase
FYA58_RS03970	COG1214	PFAM Peptidase M22, glycoprotease
FYA58_RS03975	COG1573	uracil-dna glycosylase
FYA58_RS03980	COG0477	Major facilitator Superfamily
FYA58_RS03985	COG1196	nuclear chromosome segregation
FYA58_RS03995	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FYA58_RS04000	COG1126	abc transporter atp-binding protein
FYA58_RS04005	COG0765	amino acid transport
FYA58_RS04010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYA58_RS04015	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FYA58_RS04020	COG2917	probably involved in intracellular septation
FYA58_RS04025	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FYA58_RS04030	COG1122	ATPase activity
FYA58_RS04035	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FYA58_RS04070	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FYA58_RS04100	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FYA58_RS04105	COG2878	Part of a membrane complex involved in electron transport
FYA58_RS04125	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FYA58_RS04130	COG0251	oxidation-reduction process
FYA58_RS04140	COG3228	Belongs to the MtfA family
FYA58_RS04145	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FYA58_RS04155	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FYA58_RS04165	COG0159	tryptophan synthase activity
FYA58_RS04170	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FYA58_RS04175	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FYA58_RS04190	COG1530	ribonuclease E activity
FYA58_RS04195	COG0564	pseudouridine synthase activity
FYA58_RS04200	COG0546	phosphoglycolate phosphatase activity
FYA58_RS04205	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FYA58_RS04210	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FYA58_RS04215	COG3023	N-Acetylmuramoyl-L-alanine amidase
FYA58_RS04225	COG0424	maF-like protein
FYA58_RS04235	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FYA58_RS04245	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FYA58_RS04255	COG1028	Short-chain dehydrogenase reductase Sdr
FYA58_RS04260	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FYA58_RS04265	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FYA58_RS04290	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FYA58_RS04325	COG0481	GTPase activity
FYA58_RS04330	COG0681	Belongs to the peptidase S26 family
FYA58_RS04335	COG0571	ribonuclease III activity
FYA58_RS04340	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FYA58_RS04345	COG1381	Involved in DNA repair and RecF pathway recombination
FYA58_RS04365	COG0670	Belongs to the BI1 family
FYA58_RS04380	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FYA58_RS04405	COG0583	DNA-binding transcription factor activity
FYA58_RS04420	COG0791	NLP P60 protein
FYA58_RS04425	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FYA58_RS04430	COG3193	protein, possibly involved in utilization of glycolate and propanediol
FYA58_RS04440	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FYA58_RS04460	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FYA58_RS04495	COG1446	asparaginase
FYA58_RS04500	COG4172	Belongs to the ABC transporter superfamily
FYA58_RS04505	COG0747	negative chemotaxis
FYA58_RS04510	COG0601	transmembrane transport
FYA58_RS04535	COG0504	CTP synthase activity
FYA58_RS04545	COG0148	phosphopyruvate hydratase activity
FYA58_RS04560	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FYA58_RS04570	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FYA58_RS04575	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FYA58_RS04615	COG1981	membrane
FYA58_RS04635	COG0039	L-malate dehydrogenase activity
FYA58_RS04640	COG2188	Transcriptional regulator
FYA58_RS04645	COG2009	succinate dehydrogenase
FYA58_RS04650	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FYA58_RS04655	COG1053	succinate dehydrogenase
FYA58_RS04660	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FYA58_RS04665	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FYA58_RS04670	COG0372	Belongs to the citrate synthase family
FYA58_RS04680	COG0583	DNA-binding transcription factor activity
FYA58_RS04685	COG3842	ATPase activity
FYA58_RS04695	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FYA58_RS04700	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FYA58_RS04710	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FYA58_RS04720	COG3128	pkhd-type hydroxylase
FYA58_RS04725	COG4774	siderophore transport
FYA58_RS04735	COG0281	malic enzyme
FYA58_RS04735	COG0280	phosphate acetyltransferase
FYA58_RS04745	COG1297	OPT oligopeptide transporter protein
FYA58_RS04750	COG0567	Dehydrogenase, E1 component
FYA58_RS04755	COG0508	dehydrogenase complex catalyzes the overall conversion of
FYA58_RS04760	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FYA58_RS04765	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FYA58_RS04770	COG1595	DNA-templated transcription, initiation
FYA58_RS04780	COG4774	siderophore transport
FYA58_RS04805	COG2183	response to ionizing radiation
FYA58_RS04810	COG1199	ATP-dependent helicase activity
FYA58_RS04820	COG0564	pseudouridine synthase activity
FYA58_RS04830	COG3243	poly(R)-hydroxyalkanoic acid synthase
FYA58_RS04835	COG1028	Short-chain dehydrogenase reductase Sdr
FYA58_RS04840	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
FYA58_RS04855	COG0672	)-iron permease
FYA58_RS04870	COG2823	Periplasmic or secreted lipoprotein
FYA58_RS04890	COG3237	CsbD-like
FYA58_RS04895	COG3038	cytochrome b561
FYA58_RS04910	COG1132	(ABC) transporter
FYA58_RS04925	COG2833	Protein of unknown function (DUF455)
FYA58_RS04930	COG2951	lytic endotransglycosylase activity
FYA58_RS04955	COG0586	Pfam SNARE associated Golgi protein
FYA58_RS05010	COG0165	Argininosuccinate lyase
FYA58_RS05030	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FYA58_RS05045	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FYA58_RS05050	COG1605	Chorismate mutase
FYA58_RS05050	COG0077	Prephenate dehydratase
FYA58_RS05055	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FYA58_RS05065	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FYA58_RS05070	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FYA58_RS05090	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FYA58_RS05095	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FYA58_RS05100	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FYA58_RS05105	COG0587	DNA-directed DNA polymerase activity
FYA58_RS05115	COG2951	lytic endotransglycosylase activity
FYA58_RS05120	COG0123	including yeast histone deacetylase and acetoin utilization protein
FYA58_RS05135	COG2985	domain, Protein
FYA58_RS05140	COG1960	acyl-CoA dehydrogenase activity
FYA58_RS05145	COG0450	alkyl hydroperoxide reductase
FYA58_RS05150	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FYA58_RS05155	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FYA58_RS05160	COG4208	sulfate ABC transporter
FYA58_RS05165	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FYA58_RS05170	COG0175	sulfate reduction
FYA58_RS05200	COG0335	large ribosomal subunit rRNA binding
FYA58_RS05215	COG3622	Belongs to the hyi family
FYA58_RS05220	COG1162	GTPase activity
FYA58_RS05225	COG0501	Belongs to the peptidase M48B family
FYA58_RS05230	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FYA58_RS05235	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FYA58_RS05240	COG3327	negative regulation of DNA-templated transcription, initiation
FYA58_RS05245	COG3396	Phenylacetate-CoA oxygenase
FYA58_RS05250	COG3460	Phenylacetate-CoA oxygenase
FYA58_RS05255	COG3396	Phenylacetate-CoA oxygenase
FYA58_RS05260	COG2151	metal-sulfur cluster biosynthetic enzyme
FYA58_RS05265	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FYA58_RS05270	COG1012	belongs to the aldehyde dehydrogenase family
FYA58_RS05275	COG1024	Enoyl-CoA hydratase
FYA58_RS05280	COG2050	protein possibly involved in aromatic compounds catabolism
FYA58_RS05310	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FYA58_RS05310	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FYA58_RS05320	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FYA58_RS05325	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FYA58_RS05330	COG2346	COG2346, Truncated hemoglobins
FYA58_RS05335	COG3642	lipopolysaccharide core region biosynthetic process
FYA58_RS05345	COG3842	ATPase activity
FYA58_RS05350	COG1176	ABC-type spermidine putrescine transport system, permease component I
FYA58_RS05355	COG1177	transmembrane transport
FYA58_RS05375	COG1322	Protein conserved in bacteria
FYA58_RS05385	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FYA58_RS05390	COG0704	Plays a role in the regulation of phosphate uptake
FYA58_RS05395	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FYA58_RS05400	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FYA58_RS05400	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FYA58_RS05405	COG1643	Atp-dependent helicase
FYA58_RS05420	COG0438	transferase activity, transferring glycosyl groups
FYA58_RS05425	COG0726	polysaccharide deacetylase
FYA58_RS05430	COG0463	Glycosyl transferase, family 2
FYA58_RS05465	COG1132	(ABC) transporter
FYA58_RS05485	COG0501	Belongs to the peptidase M48B family
FYA58_RS05530	COG1722	exodeoxyribonuclease VII activity
FYA58_RS05535	COG0142	geranyltranstransferase activity
FYA58_RS05540	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FYA58_RS05545	COG1469	GTP cyclohydrolase I activity
FYA58_RS05550	COG0360	Binds together with S18 to 16S ribosomal RNA
FYA58_RS05555	COG2965	DNA replication, synthesis of RNA primer
FYA58_RS05560	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FYA58_RS05565	COG0359	binds to the 23S rRNA
FYA58_RS05575	COG0305	Participates in initiation and elongation during chromosome replication
FYA58_RS05585	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FYA58_RS05590	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FYA58_RS05595	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FYA58_RS05600	COG3737	Protein of unknown function (DUF498/DUF598)
FYA58_RS05605	COG0436	Aminotransferase
FYA58_RS05630	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FYA58_RS05635	COG0308	aminopeptidase N
FYA58_RS05650	COG0312	modulator of DNA gyrase
FYA58_RS05655	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FYA58_RS05675	COG0277	FAD linked oxidase domain protein
FYA58_RS05680	COG0277	FAD linked oxidase domain protein
FYA58_RS05685	COG0247	lactate metabolic process
FYA58_RS05725	COG0583	DNA-binding transcription factor activity
FYA58_RS05730	COG0482	sulfurtransferase activity
FYA58_RS05735	COG0730	response to heat
FYA58_RS05740	COG0625	glutathione transferase activity
FYA58_RS05745	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FYA58_RS05750	COG3909	cytochrome
FYA58_RS05785	COG3706	GGDEF domain
FYA58_RS05800	COG2826	transposase and inactivated derivatives, IS30 family
FYA58_RS05820	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
FYA58_RS05845	COG0069	glutamate synthase activity
FYA58_RS05850	COG2391	methyltransferase activity
FYA58_RS05855	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FYA58_RS05860	COG0679	Auxin Efflux Carrier
FYA58_RS05865	COG2153	protein acetylation
FYA58_RS05885	COG0557	exoribonuclease II activity
FYA58_RS05890	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FYA58_RS05895	COG2873	o-acetylhomoserine
FYA58_RS05900	COG0776	regulation of translation
FYA58_RS05930	COG0642	Histidine kinase
FYA58_RS05935	COG3158	transport of potassium into the cell
FYA58_RS05960	COG0137	argininosuccinate synthase activity
FYA58_RS05965	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FYA58_RS05970	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FYA58_RS05980	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FYA58_RS05995	COG2186	Transcriptional regulator
FYA58_RS06025	COG3836	Belongs to the HpcH HpaI aldolase family
FYA58_RS06030	COG0268	Binds directly to 16S ribosomal RNA
FYA58_RS06075	COG0728	peptidoglycan biosynthetic process
FYA58_RS06085	COG0563	adenylate kinase activity
FYA58_RS06090	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FYA58_RS06095	COG2835	tetraacyldisaccharide 4'-kinase activity
FYA58_RS06100	COG1663	tetraacyldisaccharide 4'-kinase activity
FYA58_RS06105	COG0848	biopolymer transport protein
FYA58_RS06110	COG0811	peptide transport
FYA58_RS06115	COG1570	exodeoxyribonuclease VII activity
FYA58_RS06120	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FYA58_RS06130	COG0038	chloride channel
FYA58_RS06135	COG0183	Belongs to the thiolase family
FYA58_RS06145	COG1278	Cold shock
FYA58_RS06150	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FYA58_RS06160	COG4953	penicillin-binding protein 1C
FYA58_RS06175	COG3008	intermembrane lipid transfer
FYA58_RS06185	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FYA58_RS06185	COG0506	proline dehydrogenase activity
FYA58_RS06185	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FYA58_RS06215	COG0004	ammonium transporteR
FYA58_RS06220	COG0347	Belongs to the P(II) protein family
FYA58_RS06265	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FYA58_RS06270	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FYA58_RS06275	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FYA58_RS06280	COG0072	phenylalanine-tRNA ligase activity
FYA58_RS06280	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FYA58_RS06285	COG0776	regulation of translation
FYA58_RS06315	COG1802	Transcriptional regulator
FYA58_RS06320	COG3181	Tripartite tricarboxylate transporter family receptor
FYA58_RS06340	COG1278	Cold shock
FYA58_RS06350	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FYA58_RS06370	COG1522	sequence-specific DNA binding
FYA58_RS06420	COG5265	(ABC) transporter
FYA58_RS06440	COG0656	L-ascorbic acid biosynthetic process
FYA58_RS06445	COG0667	Aldo Keto reductase
FYA58_RS06460	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FYA58_RS06505	COG1610	YqeY-like protein
FYA58_RS06520	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FYA58_RS06525	COG3246	L-lysine catabolic process to acetate
FYA58_RS06545	COG0318	PFAM AMP-dependent synthetase and ligase
FYA58_RS06560	COG0183	Belongs to the thiolase family
FYA58_RS06565	COG1024	Enoyl-CoA hydratase
FYA58_RS06565	COG1250	3-hydroxyacyl-CoA dehydrogenase
FYA58_RS06575	COG1250	3-hydroxyacyl-CoA dehydrogenase
FYA58_RS06575	COG1024	Enoyl-CoA hydratase
FYA58_RS06580	COG0183	Belongs to the thiolase family
FYA58_RS06585	COG1960	acyl-CoA dehydrogenase activity
FYA58_RS06595	COG1045	serine acetyltransferase
FYA58_RS06605	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FYA58_RS06610	COG0483	inositol monophosphate 1-phosphatase activity
FYA58_RS06615	COG1012	belongs to the aldehyde dehydrogenase family
FYA58_RS06620	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FYA58_RS06635	COG0210	DNA helicase
FYA58_RS06640	COG0598	Magnesium transport protein CorA
FYA58_RS06650	COG0747	negative chemotaxis
FYA58_RS06655	COG0601	transmembrane transport
FYA58_RS06660	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FYA58_RS06665	COG4172	Belongs to the ABC transporter superfamily
FYA58_RS06685	COG1346	cytolysis
FYA58_RS06695	COG1028	Short-chain dehydrogenase reductase Sdr
FYA58_RS06700	COG0783	Belongs to the Dps family
FYA58_RS06720	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
FYA58_RS06730	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FYA58_RS06735	COG1845	cytochrome c oxidase, subunit III
FYA58_RS06740	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FYA58_RS06785	COG1666	GTP binding
FYA58_RS06810	COG1028	Short-chain dehydrogenase reductase Sdr
FYA58_RS06815	COG5006	permease, DMT superfamily
FYA58_RS06840	COG2264	protein methyltransferase activity
FYA58_RS06875	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FYA58_RS06880	COG0746	molybdenum cofactor guanylyltransferase activity
FYA58_RS06885	COG0303	'Molybdopterin
FYA58_RS06890	COG0521	Mo-molybdopterin cofactor biosynthetic process
FYA58_RS06895	COG0314	molybdopterin synthase activity
FYA58_RS06905	COG0315	cyclic pyranopterin monophosphate synthase activity
FYA58_RS06910	COG0412	Dienelactone hydrolase
FYA58_RS06920	COG0678	peroxiredoxin activity
FYA58_RS06935	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FYA58_RS06945	COG0542	response to heat
FYA58_RS06960	COG1477	protein flavinylation
FYA58_RS06985	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FYA58_RS06990	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
FYA58_RS06990	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
FYA58_RS06995	COG1562	ergosterol biosynthetic process
FYA58_RS07000	COG1562	ergosterol biosynthetic process
FYA58_RS07005	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FYA58_RS07045	COG0254	rRNA binding
FYA58_RS07050	COG3483	tryptophan 2,3-dioxygenase activity
FYA58_RS07055	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FYA58_RS07060	COG2003	Belongs to the UPF0758 family
FYA58_RS07070	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FYA58_RS07075	COG0625	glutathione transferase activity
FYA58_RS07095	COG0523	cobalamin synthesis protein
FYA58_RS07105	COG0583	DNA-binding transcription factor activity
FYA58_RS07115	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FYA58_RS07120	COG1187	pseudouridine synthase activity
FYA58_RS07125	COG0779	Required for maturation of 30S ribosomal subunits
FYA58_RS07130	COG0195	Participates in both transcription termination and antitermination
FYA58_RS07130	COG2251	uridine kinase activity
FYA58_RS07135	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FYA58_RS07140	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FYA58_RS07145	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FYA58_RS07150	COG1217	gtp-binding protein TYPA
FYA58_RS07165	COG1802	Transcriptional regulator
FYA58_RS07175	COG1024	Enoyl-CoA hydratase
FYA58_RS07180	COG0318	PFAM AMP-dependent synthetase and ligase
FYA58_RS07190	COG2032	superoxide dismutase activity
FYA58_RS07205	COG4120	Belongs to the binding-protein-dependent transport system permease family
FYA58_RS07210	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FYA58_RS07215	COG0725	ABC transporter, periplasmic molybdate-binding protein
FYA58_RS07220	COG4149	molybdate abc transporter
FYA58_RS07250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYA58_RS07255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYA58_RS07260	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FYA58_RS07270	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FYA58_RS07275	COG0736	holo-[acyl-carrier-protein] synthase activity
FYA58_RS07280	COG1472	Belongs to the glycosyl hydrolase 3 family
FYA58_RS07285	COG0322	excinuclease ABC activity
FYA58_RS07290	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FYA58_RS07300	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FYA58_RS07300	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FYA58_RS07305	COG2224	Isocitrate lyase
FYA58_RS07310	COG1846	Transcriptional regulator
FYA58_RS07315	COG1764	response to oxidative stress
FYA58_RS07320	COG1131	(ABC) transporter
FYA58_RS07330	COG0628	permease
FYA58_RS07350	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
FYA58_RS07360	COG2814	Major facilitator Superfamily
FYA58_RS07380	COG3015	lipoprotein NlpE involved in copper resistance
FYA58_RS07390	COG3530	Putative quorum-sensing-regulated virulence factor
FYA58_RS07405	COG0494	nUDIX hydrolase
FYA58_RS07415	COG0697	spore germination
FYA58_RS07420	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FYA58_RS07445	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FYA58_RS07450	COG1702	phosphate starvation-inducible protein PhoH
FYA58_RS07455	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FYA58_RS07460	COG4535	Mg2 and Co2 transporter CorC
FYA58_RS07465	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FYA58_RS07470	COG0667	Aldo Keto reductase
FYA58_RS07490	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FYA58_RS07495	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FYA58_RS07500	COG1862	Preprotein translocase
FYA58_RS07505	COG0343	queuine tRNA-ribosyltransferase activity
FYA58_RS07510	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FYA58_RS07515	COG2027	D-alanyl-D-alanine carboxypeptidase
FYA58_RS07520	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FYA58_RS07525	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FYA58_RS07525	COG1648	precorrin-2 dehydrogenase activity
FYA58_RS07535	COG4575	ribosome binding
FYA58_RS07560	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FYA58_RS07565	COG0741	lytic transglycosylase activity
FYA58_RS07570	COG0436	Aminotransferase
FYA58_RS07580	COG0280	phosphate acetyltransferase
FYA58_RS07580	COG0281	malic enzyme
FYA58_RS07595	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FYA58_RS07600	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FYA58_RS07605	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FYA58_RS07610	COG0126	phosphoglycerate kinase activity
FYA58_RS07625	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FYA58_RS07640	COG0625	glutathione transferase activity
FYA58_RS07660	COG0789	Transcriptional regulator
FYA58_RS07675	COG0306	phosphate transporter
FYA58_RS07680	COG0521	Mo-molybdopterin cofactor biosynthetic process
FYA58_RS07690	COG0739	heme binding
FYA58_RS07700	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FYA58_RS07740	COG0456	acetyltransferase
FYA58_RS07745	COG1301	dicarboxylic acid transport
FYA58_RS07755	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FYA58_RS07760	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FYA58_RS07765	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FYA58_RS07770	COG0009	L-threonylcarbamoyladenylate synthase
FYA58_RS07780	COG4771	TonB-dependent receptor
FYA58_RS07810	COG1960	acyl-CoA dehydrogenase activity
FYA58_RS07815	COG0028	Belongs to the TPP enzyme family
FYA58_RS07820	COG0583	DNA-binding transcription factor activity
FYA58_RS07825	COG4974	Belongs to the 'phage' integrase family
FYA58_RS07830	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FYA58_RS07835	COG1686	Belongs to the peptidase S11 family
FYA58_RS07865	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FYA58_RS07870	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FYA58_RS07875	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FYA58_RS07895	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FYA58_RS07900	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FYA58_RS07905	COG0505	Belongs to the CarA family
FYA58_RS07910	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FYA58_RS07920	COG1028	Short-chain dehydrogenase reductase Sdr
FYA58_RS07925	COG0406	alpha-ribazole phosphatase activity
FYA58_RS07955	COG2233	PERMEase
FYA58_RS07960	COG3620	sequence-specific DNA binding
FYA58_RS07970	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FYA58_RS07980	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FYA58_RS07985	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FYA58_RS07995	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FYA58_RS08010	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FYA58_RS08030	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FYA58_RS08090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FYA58_RS08120	COG0540	Belongs to the ATCase OTCase family
FYA58_RS08125	COG2974	May be involved in recombination
FYA58_RS08150	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FYA58_RS08155	COG2137	regulation of response to DNA damage stimulus
FYA58_RS08165	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FYA58_RS08185	COG0045	succinate-CoA ligase (ADP-forming) activity
FYA58_RS08190	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FYA58_RS08195	COG0861	Integral membrane protein TerC family
FYA58_RS08200	COG0861	Integral membrane protein TerC family
FYA58_RS08205	COG0181	hydroxymethylbilane synthase activity
FYA58_RS08245	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FYA58_RS08290	COG1450	Type ii and iii secretion system protein
FYA58_RS08340	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FYA58_RS08350	COG1295	ribonuclease BN
FYA58_RS08360	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FYA58_RS08380	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FYA58_RS08385	COG0501	Belongs to the peptidase M48B family
FYA58_RS08390	COG2197	response regulator
FYA58_RS08415	COG0066	3-isopropylmalate dehydratase activity
FYA58_RS08425	COG0473	3-isopropylmalate dehydrogenase activity
FYA58_RS08430	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FYA58_RS08440	COG0101	tRNA pseudouridine synthase activity
FYA58_RS08445	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FYA58_RS08450	COG0135	phosphoribosylanthranilate isomerase activity
FYA58_RS08470	COG2801	Transposase and inactivated derivatives
FYA58_RS08475	COG2801	Transposase and inactivated derivatives
FYA58_RS08515	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FYA58_RS08520	COG2197	response regulator
FYA58_RS08525	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FYA58_RS08530	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FYA58_RS08545	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FYA58_RS08550	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FYA58_RS08560	COG1764	response to oxidative stress
FYA58_RS08575	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYA58_RS08580	COG0765	amino acid transport
FYA58_RS08585	COG0765	amino acid transport
FYA58_RS08595	COG0756	dUTP diphosphatase activity
FYA58_RS08625	COG1522	sequence-specific DNA binding
FYA58_RS08645	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FYA58_RS08650	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FYA58_RS08655	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FYA58_RS08660	COG0196	riboflavin kinase activity
FYA58_RS08670	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FYA58_RS08670	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FYA58_RS08700	COG0210	DNA helicase
FYA58_RS08705	COG4771	TonB-dependent receptor
FYA58_RS08710	COG0488	(ABC) transporter
FYA58_RS08715	COG2890	protein-(glutamine-N5) methyltransferase activity
FYA58_RS08720	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FYA58_RS08725	COG2171	N-acyltransferase activity
FYA58_RS08780	COG2801	Transposase and inactivated derivatives
FYA58_RS08820	COG2814	Major facilitator Superfamily
FYA58_RS08845	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FYA58_RS08850	COG2900	Belongs to the SlyX family
FYA58_RS08865	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FYA58_RS08885	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FYA58_RS08910	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FYA58_RS08915	COG0583	DNA-binding transcription factor activity
FYA58_RS08920	COG1028	Short-chain dehydrogenase reductase Sdr
FYA58_RS08930	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FYA58_RS08935	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FYA58_RS08950	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FYA58_RS08955	COG0508	dehydrogenase complex catalyzes the overall conversion of
FYA58_RS08960	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FYA58_RS08970	COG4566	intracellular signal transduction
FYA58_RS08975	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FYA58_RS08995	COG1999	signal sequence binding
FYA58_RS09015	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYA58_RS09020	COG0583	DNA-binding transcription factor activity
FYA58_RS09025	COG1187	pseudouridine synthase activity
FYA58_RS09030	COG3161	chorismate lyase activity
FYA58_RS09045	COG1280	lysine exporter protein (LysE YggA)
FYA58_RS09085	COG1129	ABC transporter
FYA58_RS09100	COG0583	DNA-binding transcription factor activity
FYA58_RS09130	COG1185	polyribonucleotide nucleotidyltransferase activity
FYA58_RS09135	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FYA58_RS09150	COG1183	phosphatidylcholine synthase activity
FYA58_RS09160	COG0440	acetolactate synthase activity
FYA58_RS09165	COG0028	Belongs to the TPP enzyme family
FYA58_RS09190	COG3022	response to hydroperoxide
FYA58_RS09200	COG1028	Short-chain dehydrogenase reductase Sdr
FYA58_RS09215	COG3486	L-lysine 6-monooxygenase (NADPH) activity
FYA58_RS09245	COG2814	Major facilitator Superfamily
FYA58_RS09275	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FYA58_RS09310	COG2733	membrane
FYA58_RS09335	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FYA58_RS09355	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYA58_RS09360	COG0842	Transport permease protein
FYA58_RS09360	COG1129	ABC transporter
FYA58_RS09365	COG0842	Transport permease protein
FYA58_RS09375	COG1028	Short-chain dehydrogenase reductase Sdr
FYA58_RS09385	COG2259	Doxx family
FYA58_RS09415	COG0415	Belongs to the DNA photolyase family
FYA58_RS09435	COG0386	Belongs to the glutathione peroxidase family
FYA58_RS09450	COG0095	Lipoate-protein ligase
FYA58_RS09460	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FYA58_RS09470	COG0010	Belongs to the arginase family
FYA58_RS09480	COG0765	amino acid transport
FYA58_RS09485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYA58_RS09500	COG0084	hydrolase, TatD family'
FYA58_RS09510	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FYA58_RS09515	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FYA58_RS09525	COG2175	clavaminate synthase activity
FYA58_RS09530	COG0583	DNA-binding transcription factor activity
FYA58_RS09555	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FYA58_RS09565	COG2914	Belongs to the UPF0125 (RnfH) family
FYA58_RS09575	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FYA58_RS09610	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FYA58_RS09610	COG0519	Catalyzes the synthesis of GMP from XMP
FYA58_RS09620	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FYA58_RS09630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FYA58_RS09635	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FYA58_RS09640	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FYA58_RS09650	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FYA58_RS09655	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FYA58_RS09665	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FYA58_RS09670	COG0750	zinc metalloprotease
FYA58_RS09675	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FYA58_RS09685	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FYA58_RS09690	COG0233	cytoplasmic translational termination
FYA58_RS09695	COG0528	UMP kinase activity
FYA58_RS09700	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FYA58_RS09705	COG0052	Belongs to the universal ribosomal protein uS2 family
FYA58_RS09710	COG0024	Methionine aminopeptidase
FYA58_RS09715	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FYA58_RS09735	COG1286	toxin biosynthetic process
FYA58_RS09745	COG0285	dihydrofolate synthase activity
FYA58_RS09755	COG3181	Tripartite tricarboxylate transporter family receptor
FYA58_RS09760	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYA58_RS09800	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FYA58_RS09810	COG1677	Flagellar hook-basal body complex protein FliE
FYA58_RS09820	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FYA58_RS09825	COG1317	bacterial-type flagellum organization
FYA58_RS09845	COG1580	Controls the rotational direction of flagella during chemotaxis
FYA58_RS09855	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FYA58_RS09880	COG0840	transmembrane signaling receptor activity
FYA58_RS09885	COG0840	transmembrane signaling receptor activity
FYA58_RS09905	COG1191	sigma factor activity
FYA58_RS09940	COG2199	diguanylate cyclase activity
FYA58_RS09940	COG2203	Gaf domain
FYA58_RS09950	COG1619	proteins homologs of microcin C7 resistance protein MccF
FYA58_RS09975	COG1126	abc transporter atp-binding protein
FYA58_RS09980	COG0765	amino acid transport
FYA58_RS09985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYA58_RS10030	COG2200	EAL domain
FYA58_RS10050	COG1253	flavin adenine dinucleotide binding
FYA58_RS10055	COG5001	Diguanylate cyclase
FYA58_RS10055	COG3706	GGDEF domain
FYA58_RS10055	COG2203	Gaf domain
FYA58_RS10055	COG4251	negative regulation of phosphorylation
FYA58_RS10060	COG2197	response regulator
FYA58_RS10065	COG2205	protein histidine kinase activity
FYA58_RS10065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYA58_RS10090	COG0076	glutamate decarboxylase activity
FYA58_RS10095	COG2985	domain, Protein
FYA58_RS10100	COG3189	MarR family transcriptional regulator
FYA58_RS10110	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FYA58_RS10120	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FYA58_RS10120	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FYA58_RS10130	COG0028	Belongs to the TPP enzyme family
FYA58_RS10140	COG1012	belongs to the aldehyde dehydrogenase family
FYA58_RS10150	COG0688	phosphatidylethanolamine metabolic process
FYA58_RS10155	COG1304	FMN binding
FYA58_RS10160	COG1464	Belongs to the NlpA lipoprotein family
FYA58_RS10180	COG0697	spore germination
FYA58_RS10185	COG2133	pyrroloquinoline quinone binding
FYA58_RS10190	COG0625	glutathione transferase activity
FYA58_RS10200	COG1794	racemase activity, acting on amino acids and derivatives
FYA58_RS10220	COG0559	Belongs to the binding-protein-dependent transport system permease family
FYA58_RS10230	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FYA58_RS10245	COG1175	transmembrane transport
FYA58_RS10250	COG0395	ABC-type sugar transport system, permease component
FYA58_RS10255	COG3842	ATPase activity
FYA58_RS10280	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FYA58_RS10295	COG0438	transferase activity, transferring glycosyl groups
FYA58_RS10320	COG0463	Glycosyl transferase, family 2
FYA58_RS10335	COG0783	Belongs to the Dps family
FYA58_RS10340	COG0583	DNA-binding transcription factor activity
FYA58_RS10345	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FYA58_RS10375	COG1840	ABC-type Fe3 transport system, periplasmic component
FYA58_RS10385	COG3842	ATPase activity
FYA58_RS10390	COG1741	Belongs to the pirin family
FYA58_RS10395	COG1741	Belongs to the pirin family
FYA58_RS10400	COG0583	DNA-binding transcription factor activity
FYA58_RS10415	COG0174	glutamine synthetase
FYA58_RS10420	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FYA58_RS10425	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FYA58_RS10435	COG0840	transmembrane signaling receptor activity
FYA58_RS10445	COG0583	DNA-binding transcription factor activity
FYA58_RS10450	COG1960	acyl-CoA dehydrogenase activity
FYA58_RS10455	COG2079	MmgE PrpD family protein
FYA58_RS10465	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FYA58_RS10470	COG1561	YicC-like family, N-terminal region
FYA58_RS10480	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FYA58_RS10485	COG0791	NLP P60 protein
FYA58_RS10490	COG1028	Short-chain dehydrogenase reductase Sdr
FYA58_RS10495	COG0194	GDP metabolic process
FYA58_RS10500	COG1758	RNA polymerase activity
FYA58_RS10505	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FYA58_RS10510	COG1126	abc transporter atp-binding protein
FYA58_RS10515	COG0765	amino acid transport
FYA58_RS10520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYA58_RS10530	COG2831	hemolysin activation secretion protein
FYA58_RS10540	COG3188	usher protein
FYA58_RS10545	COG3121	Chaperone
FYA58_RS10560	COG3064	Membrane
FYA58_RS10560	COG3210	domain, Protein
FYA58_RS10560	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
FYA58_RS10570	COG4181	ATPase activity
FYA58_RS10580	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FYA58_RS10585	COG0584	glycerophosphoryl diester phosphodiesterase
FYA58_RS10590	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FYA58_RS10600	COG0678	peroxiredoxin activity
FYA58_RS10600	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FYA58_RS10610	COG2217	Heavy metal translocating P-type atpase
FYA58_RS10615	COG0789	Transcriptional regulator
FYA58_RS10620	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FYA58_RS10655	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FYA58_RS10665	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FYA58_RS10690	COG0583	DNA-binding transcription factor activity
FYA58_RS10695	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FYA58_RS10700	COG2252	PERMEase
FYA58_RS10705	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FYA58_RS10710	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FYA58_RS10745	COG0488	(ABC) transporter
FYA58_RS10750	COG1619	proteins homologs of microcin C7 resistance protein MccF
FYA58_RS10755	COG0590	tRNA wobble adenosine to inosine editing
FYA58_RS10770	COG1320	monovalent cation:proton antiporter activity
FYA58_RS10775	COG2212	antiporter activity
FYA58_RS10780	COG1863	multisubunit Na H antiporter MnhE subunit
FYA58_RS10785	COG0651	ATP synthesis coupled electron transport
FYA58_RS10790	COG1006	Multisubunit Na H antiporter MnhC subunit
FYA58_RS10795	COG2111	Na H antiporter
FYA58_RS10795	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FYA58_RS10800	COG3181	Tripartite tricarboxylate transporter family receptor
FYA58_RS10825	COG0420	3'-5' exonuclease activity
FYA58_RS10860	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FYA58_RS10870	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FYA58_RS10880	COG2130	NADP-dependent
FYA58_RS10885	COG1309	transcriptional regulator
FYA58_RS10895	COG1131	(ABC) transporter
FYA58_RS10900	COG0842	Transport permease protein
FYA58_RS10910	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FYA58_RS10945	COG0602	queuosine metabolic process
FYA58_RS10950	COG0720	synthase
FYA58_RS10985	COG0587	DNA-directed DNA polymerase activity
FYA58_RS10995	COG0390	transport system, permease component
FYA58_RS11000	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FYA58_RS11005	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
FYA58_RS11060	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FYA58_RS11085	COG5507	3-demethylubiquinone-9 3-methyltransferase
FYA58_RS11120	COG1396	sequence-specific DNA binding
FYA58_RS11145	COG0583	DNA-binding transcription factor activity
FYA58_RS11150	COG2814	Major facilitator Superfamily
FYA58_RS11175	COG2807	transmembrane transport
FYA58_RS11180	COG2207	Transcriptional regulator
FYA58_RS11185	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FYA58_RS11190	COG2814	Major facilitator Superfamily
FYA58_RS11205	COG1012	belongs to the aldehyde dehydrogenase family
FYA58_RS11240	COG0583	DNA-binding transcription factor activity
FYA58_RS11265	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FYA58_RS11290	COG0384	phenazine biosynthesis protein PhzF
FYA58_RS11295	COG1733	regulation of RNA biosynthetic process
FYA58_RS11330	COG3177	Filamentation induced by cAMP protein fic
FYA58_RS11340	COG0519	Catalyzes the synthesis of GMP from XMP
FYA58_RS11340	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FYA58_RS11355	COG1695	Transcriptional regulator
FYA58_RS11370	COG2072	flavoprotein involved in K transport
FYA58_RS11375	COG0601	transmembrane transport
FYA58_RS11395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FYA58_RS11405	COG4608	Belongs to the ABC transporter superfamily
FYA58_RS11410	COG0747	negative chemotaxis
FYA58_RS11450	COG0047	phosphoribosylformylglycinamidine synthase activity
FYA58_RS11450	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FYA58_RS11455	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FYA58_RS11475	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FYA58_RS11475	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FYA58_RS11480	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FYA58_RS11490	COG0613	PHP domain protein
FYA58_RS11550	COG1012	belongs to the aldehyde dehydrogenase family
FYA58_RS11560	COG0583	DNA-binding transcription factor activity
FYA58_RS11580	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FYA58_RS11590	COG3181	Tripartite tricarboxylate transporter family receptor
FYA58_RS11600	COG3181	Tripartite tricarboxylate transporter family receptor
FYA58_RS11630	COG1595	DNA-templated transcription, initiation
FYA58_RS11635	COG3712	iron ion homeostasis
FYA58_RS11645	COG0084	hydrolase, TatD family'
FYA58_RS11650	COG1136	(ABC) transporter
FYA58_RS11665	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FYA58_RS11675	COG1028	Short-chain dehydrogenase reductase Sdr
FYA58_RS11680	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FYA58_RS11690	COG1803	Methylglyoxal synthase
FYA58_RS11710	COG2801	Transposase and inactivated derivatives
FYA58_RS11715	COG2801	Transposase and inactivated derivatives
FYA58_RS11740	COG2975	iron-sulfur cluster assembly
FYA58_RS11745	COG0633	Ferredoxin
FYA58_RS11750	COG0443	Heat shock 70 kDa protein
FYA58_RS11755	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FYA58_RS11760	COG0316	Belongs to the HesB IscA family
FYA58_RS11765	COG0822	iron-sulfur transferase activity
FYA58_RS11770	COG1104	cysteine desulfurase activity
FYA58_RS11780	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FYA58_RS11785	COG0556	nucleotide-excision repair
FYA58_RS11800	COG0583	DNA-binding transcription factor activity
FYA58_RS11820	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FYA58_RS11860	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FYA58_RS11875	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FYA58_RS11885	COG0740	serine-type endopeptidase activity
FYA58_RS11890	COG0544	peptidyl-prolyl cis-trans isomerase activity
FYA58_RS11935	COG2801	Transposase and inactivated derivatives
FYA58_RS11945	COG1278	Cold shock
FYA58_RS11975	COG2433	Pfam Transposase IS66
FYA58_RS12035	COG1530	ribonuclease E activity
FYA58_RS12070	COG1846	Transcriptional regulator
FYA58_RS12080	COG1566	PFAM secretion protein HlyD family protein
FYA58_RS12085	COG2814	Major facilitator Superfamily
FYA58_RS12110	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FYA58_RS12125	COG0433	COG0433 Predicted ATPase
FYA58_RS12130	COG0217	transcriptional regulatory protein
FYA58_RS12135	COG0151	Belongs to the GarS family
FYA58_RS12145	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FYA58_RS12150	COG0799	negative regulation of ribosome biogenesis
FYA58_RS12155	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FYA58_RS12160	COG0424	maF-like protein
FYA58_RS12170	COG4191	Histidine kinase
FYA58_RS12175	COG2204	response regulator
FYA58_RS12200	COG0500	methyltransferase
FYA58_RS12215	COG0803	Belongs to the bacterial solute-binding protein 9 family
FYA58_RS12220	COG1121	(ABC) transporter
FYA58_RS12225	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FYA58_RS12230	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FYA58_RS12245	COG4993	Dehydrogenase
FYA58_RS12255	COG4772	TonB-dependent receptor
FYA58_RS12260	COG2814	Major facilitator Superfamily
FYA58_RS12280	COG0037	tRNA processing
FYA58_RS12285	COG0825	malonyl-CoA metabolic process
FYA58_RS12295	COG0215	cysteine-tRNA ligase activity
FYA58_RS12305	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FYA58_RS12310	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FYA58_RS12315	COG1968	undecaprenyl-diphosphatase activity
FYA58_RS12320	COG1253	flavin adenine dinucleotide binding
FYA58_RS12325	COG0483	inositol monophosphate 1-phosphatase activity
FYA58_RS12345	COG0668	transmembrane transport
FYA58_RS12370	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FYA58_RS12380	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FYA58_RS12395	COG1802	Transcriptional regulator
FYA58_RS12415	COG3360	Dodecin
FYA58_RS12435	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FYA58_RS12440	COG2850	peptidyl-arginine hydroxylation
FYA58_RS12450	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
FYA58_RS12455	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FYA58_RS12460	COG1994	Peptidase M50
FYA58_RS12465	COG0009	L-threonylcarbamoyladenylate synthase
FYA58_RS12470	COG2321	neutral zinc metallopeptidase
FYA58_RS12490	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FYA58_RS12500	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FYA58_RS12510	COG2271	Major facilitator Superfamily
FYA58_RS12585	COG2202	Pas domain
FYA58_RS12585	COG2200	EAL domain
FYA58_RS12585	COG2199	diguanylate cyclase activity
FYA58_RS12590	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
FYA58_RS12610	COG1960	acyl-CoA dehydrogenase activity
FYA58_RS12615	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYA58_RS12620	COG2186	Transcriptional regulator
FYA58_RS12645	COG1595	DNA-templated transcription, initiation
FYA58_RS12680	COG1028	Short-chain dehydrogenase reductase Sdr
FYA58_RS12695	COG0179	Fumarylacetoacetate (FAA) hydrolase
FYA58_RS12715	COG4604	ABC transporter, ATP-binding protein
FYA58_RS12720	COG4605	iron ion homeostasis
FYA58_RS12725	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FYA58_RS12730	COG4607	ABC-type enterochelin transport system periplasmic component
FYA58_RS12735	COG0438	transferase activity, transferring glycosyl groups
FYA58_RS12745	COG0149	triose-phosphate isomerase activity
FYA58_RS12780	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FYA58_RS12780	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FYA58_RS12785	COG0668	transmembrane transport
FYA58_RS12790	COG0165	Argininosuccinate lyase
FYA58_RS12800	COG0789	Transcriptional regulator
FYA58_RS12810	COG0501	Belongs to the peptidase M48B family
FYA58_RS12815	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FYA58_RS12840	COG1024	Enoyl-CoA hydratase
FYA58_RS12845	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYA58_RS12865	COG3468	outer membrane autotransporter barrel domain protein
FYA58_RS12910	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FYA58_RS12915	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FYA58_RS12920	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FYA58_RS12925	COG1674	ftsk spoiiie
FYA58_RS12930	COG0492	ferredoxin-NADP+ reductase activity
FYA58_RS12935	COG1193	negative regulation of DNA recombination
FYA58_RS12950	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FYA58_RS12965	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FYA58_RS12970	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FYA58_RS12975	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FYA58_RS12985	COG0745	RESPONSE REGULATOR receiver
FYA58_RS13020	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FYA58_RS13040	COG0612	Peptidase, M16
FYA58_RS13050	COG0443	Heat shock 70 kDa protein
FYA58_RS13060	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FYA58_RS13070	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FYA58_RS13075	COG1420	regulation of RNA biosynthetic process
FYA58_RS13080	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FYA58_RS13085	COG0497	DNA recombination
FYA58_RS13115	COG0735	belongs to the Fur family
FYA58_RS13120	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FYA58_RS13165	COG2828	Protein conserved in bacteria
FYA58_RS13170	COG1280	lysine exporter protein (LysE YggA)
FYA58_RS13175	COG3181	Tripartite tricarboxylate transporter family receptor
FYA58_RS13190	COG1028	Short-chain dehydrogenase reductase Sdr
FYA58_RS13195	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FYA58_RS13200	COG1802	Transcriptional regulator
FYA58_RS13205	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FYA58_RS13210	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FYA58_RS13215	COG1335	isochorismatase
FYA58_RS13220	COG0523	cobalamin synthesis protein
FYA58_RS13250	COG0583	DNA-binding transcription factor activity
FYA58_RS13260	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FYA58_RS13265	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FYA58_RS13270	COG0167	dihydroorotate dehydrogenase activity
FYA58_RS13315	COG1414	Transcriptional regulator
FYA58_RS13335	COG0513	Belongs to the DEAD box helicase family
FYA58_RS13360	COG0429	hydrolase of the alpha beta-hydrolase fold
FYA58_RS13405	COG0006	proline dipeptidase activity
FYA58_RS13415	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FYA58_RS13445	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FYA58_RS13450	COG0632	four-way junction helicase activity
FYA58_RS13465	COG2255	four-way junction helicase activity
FYA58_RS13470	COG0514	ATP-dependent DNA helicase (RecQ)
FYA58_RS13490	COG1294	oxidase, subunit
FYA58_RS13500	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FYA58_RS13505	COG0850	regulation of cytokinetic process
FYA58_RS13510	COG2894	cell division
FYA58_RS13515	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FYA58_RS13540	COG0488	(ABC) transporter
FYA58_RS13555	COG4608	Belongs to the ABC transporter superfamily
FYA58_RS13560	COG0444	Belongs to the ABC transporter superfamily
FYA58_RS13565	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FYA58_RS13580	COG1215	transferase activity, transferring glycosyl groups
FYA58_RS13585	COG0583	DNA-binding transcription factor activity
FYA58_RS13590	COG1368	sulfuric ester hydrolase activity
FYA58_RS13595	COG1686	Belongs to the peptidase S11 family
FYA58_RS13605	COG1280	lysine exporter protein (LysE YggA)
FYA58_RS13615	COG1064	alcohol dehydrogenase
FYA58_RS13620	COG4191	Histidine kinase
FYA58_RS13625	COG4566	intracellular signal transduction
FYA58_RS13635	COG1802	Transcriptional regulator
FYA58_RS13660	COG3181	Tripartite tricarboxylate transporter family receptor
FYA58_RS13665	COG0513	Belongs to the DEAD box helicase family
FYA58_RS13670	COG0668	transmembrane transport
FYA58_RS13685	COG1595	DNA-templated transcription, initiation
FYA58_RS13725	COG0583	DNA-binding transcription factor activity
FYA58_RS13730	COG0531	amino acid
FYA58_RS13735	COG1982	Orn Lys Arg decarboxylase major
FYA58_RS13760	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FYA58_RS13765	COG0459	protein refolding
FYA58_RS13775	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FYA58_RS13780	COG1252	NADH dehydrogenase
FYA58_RS13785	COG0284	orotidine-5'-phosphate decarboxylase activity
FYA58_RS13795	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FYA58_RS13805	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FYA58_RS13810	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FYA58_RS13840	COG1595	DNA-templated transcription, initiation
FYA58_RS13850	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FYA58_RS13855	COG3639	organic phosphonate transmembrane transporter activity
FYA58_RS13860	COG3639	organic phosphonate transmembrane transporter activity
FYA58_RS13875	COG0742	ribosomal rna small subunit methyltransferase
FYA58_RS13880	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FYA58_RS13885	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FYA58_RS13890	COG3135	benzoate transporter
FYA58_RS13910	COG4774	siderophore transport
FYA58_RS13935	COG1024	Enoyl-CoA hydratase
FYA58_RS13940	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FYA58_RS13945	COG1960	acyl-CoA dehydrogenase activity
FYA58_RS13955	COG0318	PFAM AMP-dependent synthetase and ligase
FYA58_RS13960	COG3181	Tripartite tricarboxylate transporter family receptor
FYA58_RS13970	COG0583	DNA-binding transcription factor activity
FYA58_RS13995	COG0277	FAD linked oxidase domain protein
FYA58_RS14015	COG1802	Transcriptional regulator
FYA58_RS14030	COG2271	Major facilitator Superfamily
FYA58_RS14040	COG0583	DNA-binding transcription factor activity
FYA58_RS14065	COG0012	GTP binding
FYA58_RS14075	COG0193	aminoacyl-tRNA hydrolase activity
FYA58_RS14080	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FYA58_RS14085	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FYA58_RS14095	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FYA58_RS14110	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FYA58_RS14135	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FYA58_RS14145	COG1368	sulfuric ester hydrolase activity
FYA58_RS14150	COG2186	Transcriptional regulator
FYA58_RS14160	COG3181	Tripartite tricarboxylate transporter family receptor
FYA58_RS14175	COG0277	FAD linked oxidase domain protein
FYA58_RS14190	COG0166	Belongs to the GPI family
FYA58_RS14195	COG0438	transferase activity, transferring glycosyl groups
FYA58_RS14200	COG0438	transferase activity, transferring glycosyl groups
FYA58_RS14215	COG0438	transferase activity, transferring glycosyl groups
FYA58_RS14230	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FYA58_RS14235	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FYA58_RS14250	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
FYA58_RS14260	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FYA58_RS14270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FYA58_RS14275	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FYA58_RS14290	COG0747	negative chemotaxis
FYA58_RS14300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FYA58_RS14305	COG4172	Belongs to the ABC transporter superfamily
FYA58_RS14330	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FYA58_RS14330	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FYA58_RS14335	COG0509	glycine decarboxylation via glycine cleavage system
FYA58_RS14340	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FYA58_RS14345	COG2081	HI0933 family
FYA58_RS14360	COG0456	acetyltransferase
FYA58_RS14365	COG0717	Belongs to the dCTP deaminase family
FYA58_RS14380	COG0489	protein tyrosine kinase activity
FYA58_RS14390	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FYA58_RS14390	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FYA58_RS14415	COG3539	Fimbrial protein
FYA58_RS14430	COG0745	RESPONSE REGULATOR receiver
FYA58_RS14460	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
FYA58_RS14475	COG2084	Dehydrogenase
FYA58_RS14480	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FYA58_RS14505	COG3842	ATPase activity
FYA58_RS14510	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FYA58_RS14515	COG1960	acyl-CoA dehydrogenase activity
FYA58_RS14525	COG0583	DNA-binding transcription factor activity
FYA58_RS14535	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYA58_RS14540	COG1024	Enoyl-CoA hydratase
FYA58_RS14560	COG0583	DNA-binding transcription factor activity
FYA58_RS14565	COG1408	metallophosphoesterase
FYA58_RS14570	COG0625	glutathione transferase activity
FYA58_RS14605	COG0426	domain, Protein
FYA58_RS14605	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FYA58_RS14610	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FYA58_RS14615	COG0583	DNA-binding transcription factor activity
FYA58_RS14625	COG1024	Enoyl-CoA hydratase
FYA58_RS14635	COG1960	acyl-CoA dehydrogenase activity
FYA58_RS14640	COG1028	Short-chain dehydrogenase reductase Sdr
FYA58_RS14645	COG1028	Short-chain dehydrogenase reductase Sdr
FYA58_RS14665	COG3181	Tripartite tricarboxylate transporter family receptor
FYA58_RS14670	COG1028	Short-chain dehydrogenase reductase Sdr
FYA58_RS14680	COG3181	Tripartite tricarboxylate transporter family receptor
FYA58_RS14720	COG0583	DNA-binding transcription factor activity
FYA58_RS14725	COG1960	acyl-CoA dehydrogenase activity
FYA58_RS14730	COG3181	Tripartite tricarboxylate transporter family receptor
FYA58_RS14735	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYA58_RS14740	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FYA58_RS14765	COG0560	Phosphoserine phosphatase
FYA58_RS14770	COG0583	DNA-binding transcription factor activity
FYA58_RS14780	COG3842	ATPase activity
FYA58_RS14795	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FYA58_RS14815	COG0625	glutathione transferase activity
FYA58_RS14855	COG4336	lyase activity
FYA58_RS14865	COG0326	Molecular chaperone. Has ATPase activity
FYA58_RS14870	COG2233	PERMEase
FYA58_RS14910	COG2818	Glycosylase
FYA58_RS14915	COG0727	PFAM Uncharacterised protein family (UPF0153)
FYA58_RS14940	COG0402	S-adenosylhomocysteine deaminase activity
FYA58_RS14955	COG0156	8-amino-7-oxononanoate synthase activity
FYA58_RS14960	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FYA58_RS15010	COG1464	Belongs to the NlpA lipoprotein family
FYA58_RS15015	COG2011	ABC-type metal ion transport system permease component
FYA58_RS15020	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FYA58_RS15025	COG1501	Belongs to the glycosyl hydrolase 31 family
FYA58_RS15030	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FYA58_RS15030	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FYA58_RS15035	COG0483	inositol monophosphate 1-phosphatase activity
FYA58_RS15040	COG0318	PFAM AMP-dependent synthetase and ligase
FYA58_RS15045	COG1473	amidohydrolase
FYA58_RS15050	COG0583	DNA-binding transcription factor activity
FYA58_RS15055	COG2855	membrane
FYA58_RS15065	COG2239	Acts as a magnesium transporter
FYA58_RS15080	COG1522	sequence-specific DNA binding
FYA58_RS15115	COG0330	HflC and HflK could
FYA58_RS15120	COG0330	HflC and HflK could
FYA58_RS15125	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FYA58_RS15130	COG1923	regulation of RNA biosynthetic process
FYA58_RS15140	COG1160	GTP binding
FYA58_RS15145	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FYA58_RS15150	COG2976	Protein conserved in bacteria
FYA58_RS15155	COG0124	histidyl-tRNA synthetase
FYA58_RS15170	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FYA58_RS15175	COG0105	UTP biosynthetic process
FYA58_RS15180	COG0525	valine-tRNA ligase activity
FYA58_RS15190	COG0336	Belongs to the RNA methyltransferase TrmD family
FYA58_RS15195	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FYA58_RS15200	COG0228	four-way junction DNA binding
FYA58_RS15205	COG0425	Belongs to the sulfur carrier protein TusA family
FYA58_RS15210	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FYA58_RS15275	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FYA58_RS15280	COG0543	2 iron, 2 sulfur cluster binding
FYA58_RS15280	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FYA58_RS15285	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FYA58_RS15290	COG2076	Multidrug Resistance protein
FYA58_RS15295	COG0633	Ferredoxin
FYA58_RS15295	COG3217	Mosc domain protein beta barrel domain protein
FYA58_RS15300	COG5285	phytanoyl-CoA dioxygenase
FYA58_RS15305	COG0662	Cupin 2, conserved barrel domain protein
FYA58_RS15315	COG0456	acetyltransferase
FYA58_RS15330	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FYA58_RS15360	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FYA58_RS15370	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FYA58_RS15375	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FYA58_RS15380	COG1760	l-serine dehydratase
FYA58_RS15385	COG1283	sodium-dependent phosphate transmembrane transporter activity
FYA58_RS15390	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FYA58_RS15395	COG0412	Dienelactone hydrolase
FYA58_RS15400	COG0428	transporter
FYA58_RS15410	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FYA58_RS15420	COG1845	cytochrome c oxidase, subunit III
FYA58_RS15425	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FYA58_RS15435	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FYA58_RS15435	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FYA58_RS15460	COG1942	4-Oxalocrotonate Tautomerase
FYA58_RS15470	COG4176	ABC-type proline glycine betaine transport system permease component
FYA58_RS15490	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FYA58_RS15495	COG2814	Major facilitator Superfamily
FYA58_RS15500	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FYA58_RS15505	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FYA58_RS15530	COG1846	Transcriptional regulator
FYA58_RS15535	COG2814	Major facilitator Superfamily
FYA58_RS15540	COG0495	leucyl-tRNA aminoacylation
FYA58_RS15555	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FYA58_RS15575	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYA58_RS15580	COG2274	protein secretion by the type I secretion system
FYA58_RS15625	COG0427	acetyl-CoA hydrolase
FYA58_RS15635	COG3264	Mechanosensitive ion channel
FYA58_RS15635	COG1511	domain protein
FYA58_RS15640	COG0730	response to heat
FYA58_RS15655	COG2176	DNA-directed DNA polymerase activity
FYA58_RS15675	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FYA58_RS15680	COG3384	dioxygenase
FYA58_RS15695	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FYA58_RS15765	COG4964	Belongs to the GSP D family
FYA58_RS15810	COG1846	Transcriptional regulator
FYA58_RS15845	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FYA58_RS15855	COG2070	2-Nitropropane dioxygenase
FYA58_RS15860	COG2070	2-Nitropropane dioxygenase
FYA58_RS15870	COG2610	gluconate transmembrane transporter activity
FYA58_RS15885	COG1408	metallophosphoesterase
FYA58_RS15890	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FYA58_RS15890	COG0493	'glutamate synthase
FYA58_RS15895	COG2199	diguanylate cyclase activity
FYA58_RS15900	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FYA58_RS15935	COG2159	amidohydrolase
FYA58_RS15945	COG0583	DNA-binding transcription factor activity
FYA58_RS15960	COG1024	Enoyl-CoA hydratase
FYA58_RS15965	COG2186	Transcriptional regulator
FYA58_RS15970	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYA58_RS15980	COG0833	amino acid
FYA58_RS15990	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FYA58_RS16025	COG5265	(ABC) transporter
FYA58_RS16065	COG1971	Probably functions as a manganese efflux pump
FYA58_RS16070	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FYA58_RS16080	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FYA58_RS16085	COG2814	Major facilitator Superfamily
FYA58_RS16110	COG4608	Belongs to the ABC transporter superfamily
FYA58_RS16130	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FYA58_RS16140	COG3383	formate dehydrogenase (NAD+) activity
FYA58_RS16155	COG0747	negative chemotaxis
FYA58_RS16165	COG0625	glutathione transferase activity
FYA58_RS16195	COG1595	DNA-templated transcription, initiation
FYA58_RS16205	COG4774	siderophore transport
FYA58_RS16220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FYA58_RS16235	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FYA58_RS16240	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FYA58_RS16265	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYA58_RS16270	COG1024	Enoyl-CoA hydratase
FYA58_RS16305	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FYA58_RS16310	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FYA58_RS16315	COG1116	anion transmembrane transporter activity
FYA58_RS16325	COG3585	molybdate ion transport
FYA58_RS16385	COG0583	DNA-binding transcription factor activity
FYA58_RS16390	COG4948	Mandelate Racemase Muconate Lactonizing
FYA58_RS16395	COG3181	Tripartite tricarboxylate transporter family receptor
FYA58_RS16420	COG3181	Tripartite tricarboxylate transporter family receptor
FYA58_RS16425	COG3181	Tripartite tricarboxylate transporter family receptor
FYA58_RS16460	COG4177	L-phenylalanine transmembrane transporter activity
FYA58_RS16485	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FYA58_RS16500	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FYA58_RS16505	COG1538	Outer membrane efflux protein
FYA58_RS16510	COG0577	efflux transmembrane transporter activity
FYA58_RS16510	COG1136	(ABC) transporter
FYA58_RS16515	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYA58_RS16530	COG0259	pyridoxamine-phosphate oxidase activity
FYA58_RS16535	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FYA58_RS16540	COG0579	oxidoreductase
FYA58_RS16550	COG0405	Gamma-glutamyltransferase
FYA58_RS16560	COG3181	Tripartite tricarboxylate transporter family receptor
FYA58_RS16570	COG0114	fumarate hydratase activity
FYA58_RS16575	COG0802	atpase or kinase
FYA58_RS16580	COG0860	N-Acetylmuramoyl-L-alanine amidase
FYA58_RS16585	COG0586	Pfam SNARE associated Golgi protein
FYA58_RS16590	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FYA58_RS16595	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FYA58_RS16600	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FYA58_RS16615	COG0617	tRNA 3'-terminal CCA addition
FYA58_RS16650	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
FYA58_RS16660	COG1024	Enoyl-CoA hydratase
FYA58_RS16670	COG2188	Transcriptional regulator
FYA58_RS16675	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FYA58_RS16690	COG0752	glycyl-tRNA synthetase alpha subunit
FYA58_RS16695	COG0751	glycine-tRNA ligase activity
FYA58_RS16700	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FYA58_RS16705	COG0204	Acyl-transferase
FYA58_RS16735	COG0242	peptide deformylase activity
FYA58_RS16745	COG0700	Nucleoside recognition
FYA58_RS16750	COG0469	pyruvate kinase activity
FYA58_RS16755	COG1929	Belongs to the glycerate kinase type-1 family
FYA58_RS16765	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FYA58_RS16770	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FYA58_RS16775	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FYA58_RS16785	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FYA58_RS16795	COG2154	pterin-4-alpha-carbinolamine dehydratase
FYA58_RS16800	COG2885	chlorophyll binding
FYA58_RS16810	COG0667	Aldo Keto reductase
FYA58_RS16820	COG3181	Tripartite tricarboxylate transporter family receptor
FYA58_RS16840	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FYA58_RS16845	COG0288	reversible hydration of carbon dioxide
FYA58_RS16865	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FYA58_RS16875	COG4829	muconolactone delta-isomerase
FYA58_RS16880	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FYA58_RS16890	COG1414	Transcriptional regulator
FYA58_RS16895	COG1028	Short-chain dehydrogenase reductase Sdr
FYA58_RS16900	COG2031	fatty acid transporter
FYA58_RS16905	COG1250	3-hydroxyacyl-CoA dehydrogenase
FYA58_RS16915	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FYA58_RS16920	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FYA58_RS16935	COG0129	dihydroxy-acid dehydratase activity
FYA58_RS16940	COG1609	Transcriptional regulator
FYA58_RS16965	COG4106	trans-aconitate 2-methyltransferase activity
FYA58_RS16980	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FYA58_RS17015	COG0163	prenyltransferase activity
FYA58_RS17020	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FYA58_RS17025	COG2890	protein-(glutamine-N5) methyltransferase activity
FYA58_RS17030	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FYA58_RS17035	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FYA58_RS17050	COG3712	iron ion homeostasis
FYA58_RS17080	COG0659	secondary active sulfate transmembrane transporter activity
FYA58_RS17100	COG1028	Short-chain dehydrogenase reductase Sdr
FYA58_RS17110	COG4774	siderophore transport
FYA58_RS17120	COG1595	DNA-templated transcription, initiation
FYA58_RS17135	COG0142	geranyltranstransferase activity
FYA58_RS17140	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FYA58_RS17145	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FYA58_RS17150	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FYA58_RS17155	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FYA58_RS17175	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FYA58_RS17175	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FYA58_RS17180	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FYA58_RS17195	COG0583	DNA-binding transcription factor activity
FYA58_RS17200	COG0861	Integral membrane protein TerC family
FYA58_RS17215	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FYA58_RS17220	COG0793	Belongs to the peptidase S41A family
FYA58_RS17225	COG4942	peptidase
FYA58_RS17230	COG0588	phosphoglycerate mutase activity
FYA58_RS17240	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FYA58_RS17245	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FYA58_RS17250	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FYA58_RS17255	COG3181	Tripartite tricarboxylate transporter family receptor
FYA58_RS17270	COG2226	methyltransferase
FYA58_RS17275	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
FYA58_RS17280	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FYA58_RS17290	COG2204	response regulator
FYA58_RS17295	COG5000	phosphorelay sensor kinase activity
FYA58_RS17305	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FYA58_RS17305	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FYA58_RS17340	COG2188	Transcriptional regulator
FYA58_RS17355	COG0583	DNA-binding transcription factor activity
FYA58_RS17360	COG1012	belongs to the aldehyde dehydrogenase family
FYA58_RS17380	COG0546	phosphoglycolate phosphatase activity
FYA58_RS17395	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FYA58_RS17400	COG0242	peptide deformylase activity
FYA58_RS17410	COG1522	sequence-specific DNA binding
FYA58_RS17415	COG2879	small protein
FYA58_RS17420	COG1966	Carbon starvation protein
FYA58_RS17450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYA58_RS17455	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FYA58_RS17460	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FYA58_RS17465	COG3181	Tripartite tricarboxylate transporter family receptor
FYA58_RS17530	COG1172	Belongs to the binding-protein-dependent transport system permease family
FYA58_RS17565	COG0640	Transcriptional regulator
FYA58_RS17605	COG0735	belongs to the Fur family
FYA58_RS17610	COG2207	Transcriptional regulator
FYA58_RS17615	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FYA58_RS17620	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FYA58_RS17625	COG0513	Belongs to the DEAD box helicase family
FYA58_RS17650	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FYA58_RS17665	COG1305	Transglutaminase-like
FYA58_RS17705	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FYA58_RS17710	COG1950	PFAM Membrane protein of
FYA58_RS17735	COG0024	Methionine aminopeptidase
FYA58_RS17740	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FYA58_RS17750	COG1560	Kdo2-lipid A biosynthetic process
FYA58_RS17755	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FYA58_RS17765	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FYA58_RS17800	COG0735	belongs to the Fur family
FYA58_RS17805	COG0523	cobalamin synthesis protein
FYA58_RS17820	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FYA58_RS17830	COG2096	Adenosyltransferase
FYA58_RS17835	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FYA58_RS17840	COG0321	lipoyl(octanoyl) transferase activity
FYA58_RS17850	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FYA58_RS17855	COG1686	Belongs to the peptidase S11 family
FYA58_RS17880	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FYA58_RS17890	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FYA58_RS17900	COG0859	PFAM glycosyl transferase family 9
FYA58_RS17935	COG0477	Major facilitator Superfamily
FYA58_RS17950	COG3568	Endonuclease Exonuclease Phosphatase
FYA58_RS17955	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FYA58_RS17985	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FYA58_RS17990	COG1956	GAF domain-containing protein
FYA58_RS17995	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FYA58_RS18010	COG2186	Transcriptional regulator
FYA58_RS18015	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FYA58_RS18030	COG1840	ABC-type Fe3 transport system, periplasmic component
FYA58_RS18070	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FYA58_RS18075	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FYA58_RS18080	COG1086	Polysaccharide biosynthesis protein
FYA58_RS18110	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FYA58_RS18120	COG1028	Short-chain dehydrogenase reductase Sdr
FYA58_RS18125	COG1012	belongs to the aldehyde dehydrogenase family
FYA58_RS18150	COG1522	sequence-specific DNA binding
FYA58_RS18155	COG3781	membrane
FYA58_RS18195	COG2200	EAL domain
FYA58_RS18205	COG0592	DNA-directed DNA polymerase activity
FYA58_RS18210	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FYA58_RS18215	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FYA58_RS18220	COG0594	ribonuclease P activity
FYA58_RS18225	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FYA58_RS18230	COG0706	membrane insertase activity
FYA58_RS18235	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FYA58_RS18240	COG1473	amidohydrolase
FYA58_RS18245	COG4608	Belongs to the ABC transporter superfamily
FYA58_RS18250	COG0444	Belongs to the ABC transporter superfamily
FYA58_RS18255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FYA58_RS18260	COG0601	transmembrane transport
FYA58_RS18270	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FYA58_RS18275	COG1505	serine-type exopeptidase activity
FYA58_RS18285	COG0281	malic enzyme
FYA58_RS18285	COG0280	phosphate acetyltransferase
FYA58_RS18315	COG0436	Aminotransferase
FYA58_RS18320	COG1278	Cold shock