locus-tag	class	description
FYA61_RS00005	COG0445	tRNA wobble uridine modification
FYA61_RS00010	COG0357	Ribosomal RNA small subunit methyltransferase G
FYA61_RS00015	COG1192	Involved in chromosome partitioning
FYA61_RS00020	COG1475	DNA binding
FYA61_RS00025	COG0252	asparaginase activity
FYA61_RS00045	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FYA61_RS00055	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FYA61_RS00065	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FYA61_RS00070	COG0081	regulation of translation
FYA61_RS00075	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FYA61_RS00080	COG0222	ribosome binding
FYA61_RS00085	COG0085	RNA polymerase activity
FYA61_RS00090	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FYA61_RS00125	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FYA61_RS00130	COG0049	tRNA binding
FYA61_RS00135	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FYA61_RS00140	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FYA61_RS00145	COG0051	transcription antitermination factor activity, RNA binding
FYA61_RS00150	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FYA61_RS00155	COG0088	Forms part of the polypeptide exit tunnel
FYA61_RS00160	COG0089	rRNA binding
FYA61_RS00165	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FYA61_RS00170	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FYA61_RS00175	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FYA61_RS00180	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FYA61_RS00185	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FYA61_RS00190	COG0255	Belongs to the universal ribosomal protein uL29 family
FYA61_RS00195	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FYA61_RS00205	COG4177	L-phenylalanine transmembrane transporter activity
FYA61_RS00215	COG1129	ABC transporter
FYA61_RS00220	COG0411	ABC transporter
FYA61_RS00250	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FYA61_RS00255	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FYA61_RS00260	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FYA61_RS00265	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FYA61_RS00270	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FYA61_RS00275	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FYA61_RS00280	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FYA61_RS00285	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FYA61_RS00290	COG1841	ribosomal large subunit assembly
FYA61_RS00295	COG0200	Binds to the 23S rRNA
FYA61_RS00300	COG0201	protein transport
FYA61_RS00305	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FYA61_RS00310	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FYA61_RS00315	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FYA61_RS00320	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FYA61_RS00325	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FYA61_RS00330	COG0202	RNA polymerase activity
FYA61_RS00335	COG0203	ribosomal protein L17
FYA61_RS00340	COG0537	adenosine 5'-monophosphoramidase activity
FYA61_RS00345	COG1324	tolerance protein
FYA61_RS00350	COG4232	protein-disulfide reductase activity
FYA61_RS00365	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FYA61_RS00375	COG1333	cytochrome c biogenesis protein
FYA61_RS00380	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FYA61_RS00395	COG1965	Belongs to the frataxin family
FYA61_RS00405	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FYA61_RS00410	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FYA61_RS00415	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FYA61_RS00435	COG2814	Major facilitator Superfamily
FYA61_RS00460	COG2801	Transposase and inactivated derivatives
FYA61_RS00490	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FYA61_RS00495	COG2922	Belongs to the Smg family
FYA61_RS00500	COG1629	transport
FYA61_RS00510	COG2358	TRAP transporter, solute receptor (TAXI family
FYA61_RS00520	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FYA61_RS00535	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FYA61_RS00540	COG0183	Belongs to the thiolase family
FYA61_RS00545	COG1960	acyl-CoA dehydrogenase activity
FYA61_RS00570	COG2200	EAL domain
FYA61_RS00575	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FYA61_RS00585	COG0018	arginyl-trna synthetase
FYA61_RS00600	COG0154	amidase activity
FYA61_RS00605	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FYA61_RS00615	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FYA61_RS00625	COG0697	spore germination
FYA61_RS00685	COG3350	monooxygenase activity
FYA61_RS00710	COG1309	transcriptional regulator
FYA61_RS00740	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FYA61_RS00745	COG1280	lysine exporter protein (LysE YggA)
FYA61_RS00750	COG0513	Belongs to the DEAD box helicase family
FYA61_RS00760	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
FYA61_RS00765	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FYA61_RS00795	COG2969	positive regulation of protein catabolic process
FYA61_RS00800	COG0625	glutathione transferase activity
FYA61_RS00805	COG2857	Cytochrome c1
FYA61_RS00810	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FYA61_RS00815	COG0723	plastoquinol--plastocyanin reductase activity
FYA61_RS00820	COG1970	mechanosensitive ion channel activity
FYA61_RS00825	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FYA61_RS00830	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FYA61_RS00840	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FYA61_RS00845	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FYA61_RS00855	COG0140	phosphoribosyl-ATP diphosphatase activity
FYA61_RS00860	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FYA61_RS00865	COG0107	imidazoleglycerol-phosphate synthase activity
FYA61_RS00870	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FYA61_RS00880	COG0131	Imidazoleglycerol-phosphate dehydratase
FYA61_RS00885	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FYA61_RS00890	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FYA61_RS00895	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FYA61_RS00900	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FYA61_RS00905	COG0271	Belongs to the BolA IbaG family
FYA61_RS00910	COG0842	Transport permease protein
FYA61_RS00915	COG1131	(ABC) transporter
FYA61_RS00930	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FYA61_RS00935	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FYA61_RS00940	COG1127	ABC transporter
FYA61_RS00960	COG0069	glutamate synthase activity
FYA61_RS00960	COG0070	glutamate synthase
FYA61_RS00960	COG0067	glutamate synthase
FYA61_RS00985	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FYA61_RS01005	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FYA61_RS01010	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FYA61_RS01055	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FYA61_RS01090	COG0109	protoheme IX farnesyltransferase activity
FYA61_RS01095	COG1999	signal sequence binding
FYA61_RS01115	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FYA61_RS01120	COG2814	Major facilitator Superfamily
FYA61_RS01135	COG1522	sequence-specific DNA binding
FYA61_RS01200	COG4948	Mandelate Racemase Muconate Lactonizing
FYA61_RS01215	COG3119	arylsulfatase activity
FYA61_RS01250	COG0402	S-adenosylhomocysteine deaminase activity
FYA61_RS01260	COG1304	FMN binding
FYA61_RS01265	COG1254	Belongs to the acylphosphatase family
FYA61_RS01275	COG3181	Tripartite tricarboxylate transporter family receptor
FYA61_RS01285	COG1414	Transcriptional regulator
FYA61_RS01305	COG0028	Belongs to the TPP enzyme family
FYA61_RS01310	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FYA61_RS01315	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYA61_RS01320	COG1960	acyl-CoA dehydrogenase activity
FYA61_RS01355	COG3181	Tripartite tricarboxylate transporter family receptor
FYA61_RS01360	COG0583	DNA-binding transcription factor activity
FYA61_RS01375	COG0129	dihydroxy-acid dehydratase activity
FYA61_RS01380	COG2084	Dehydrogenase
FYA61_RS01395	COG1671	Belongs to the UPF0178 family
FYA61_RS01400	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FYA61_RS01410	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FYA61_RS01415	COG0443	Heat shock 70 kDa protein
FYA61_RS01440	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FYA61_RS01440	COG2169	Transcriptional regulator
FYA61_RS01455	COG1683	Conserved Protein
FYA61_RS01460	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FYA61_RS01475	COG1120	ATPase activity
FYA61_RS01480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FYA61_RS01485	COG4558	Periplasmic binding protein
FYA61_RS01490	COG3720	iron ion transport
FYA61_RS01500	COG3712	iron ion homeostasis
FYA61_RS01505	COG1595	DNA-templated transcription, initiation
FYA61_RS01525	COG1607	acyl-coa hydrolase
FYA61_RS01540	COG0437	4 iron, 4 sulfur cluster binding
FYA61_RS01545	COG2864	formate dehydrogenase
FYA61_RS01560	COG3276	selenocysteine insertion sequence binding
FYA61_RS01595	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FYA61_RS01600	COG0512	Glutamine amidotransferase of anthranilate synthase
FYA61_RS01610	COG0546	phosphoglycolate phosphatase activity
FYA61_RS01615	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FYA61_RS01620	COG2967	ApaG domain
FYA61_RS01625	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FYA61_RS01630	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FYA61_RS01635	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FYA61_RS01640	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FYA61_RS01645	COG0037	tRNA processing
FYA61_RS01665	COG1024	Enoyl-CoA hydratase
FYA61_RS01680	COG0356	it plays a direct role in the translocation of protons across the membrane
FYA61_RS01690	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FYA61_RS01695	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FYA61_RS01700	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FYA61_RS01705	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FYA61_RS01710	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FYA61_RS01715	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FYA61_RS01730	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FYA61_RS01735	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FYA61_RS01740	COG0210	DNA helicase
FYA61_RS01755	COG4608	Belongs to the ABC transporter superfamily
FYA61_RS01760	COG0444	Belongs to the ABC transporter superfamily
FYA61_RS01765	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FYA61_RS01790	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FYA61_RS01795	COG1024	Enoyl-CoA hydratase
FYA61_RS01800	COG1024	Enoyl-CoA hydratase
FYA61_RS01805	COG2070	2-Nitropropane dioxygenase
FYA61_RS01820	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYA61_RS01825	COG1250	3-hydroxyacyl-CoA dehydrogenase
FYA61_RS01845	COG2267	carboxylic ester hydrolase activity
FYA61_RS01865	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FYA61_RS01875	COG2813	Specifically methylates the guanine in position
FYA61_RS01875	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FYA61_RS01880	COG2223	nitrite transmembrane transporter activity
FYA61_RS01885	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FYA61_RS01900	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FYA61_RS01905	COG0708	Exodeoxyribonuclease III
FYA61_RS01910	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FYA61_RS01915	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FYA61_RS01920	COG0154	amidase activity
FYA61_RS01925	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FYA61_RS01930	COG1077	Cell shape determining protein MreB Mrl
FYA61_RS01935	COG1792	Involved in formation and maintenance of cell shape
FYA61_RS01945	COG0768	penicillin binding
FYA61_RS01950	COG0772	Belongs to the SEDS family
FYA61_RS01955	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FYA61_RS01960	COG0471	metal ion transport
FYA61_RS01965	COG1309	transcriptional regulator
FYA61_RS01975	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FYA61_RS01990	COG2823	Periplasmic or secreted lipoprotein
FYA61_RS01995	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FYA61_RS02000	COG0792	nuclease activity
FYA61_RS02020	COG1660	Displays ATPase and GTPase activities
FYA61_RS02035	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FYA61_RS02045	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FYA61_RS02055	COG3181	Tripartite tricarboxylate transporter family receptor
FYA61_RS02060	COG1473	amidohydrolase
FYA61_RS02065	COG1137	ATPase activity
FYA61_RS02080	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FYA61_RS02090	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FYA61_RS02110	COG1294	oxidase, subunit
FYA61_RS02120	COG4988	ABC transporter
FYA61_RS02125	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FYA61_RS02130	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FYA61_RS02145	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FYA61_RS02150	COG1238	metal cluster binding
FYA61_RS02160	COG1802	Transcriptional regulator
FYA61_RS02170	COG1984	allophanate hydrolase subunit 2
FYA61_RS02175	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FYA61_RS02185	COG0583	DNA-binding transcription factor activity
FYA61_RS02190	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FYA61_RS02195	COG5002	protein histidine kinase activity
FYA61_RS02200	COG0745	RESPONSE REGULATOR receiver
FYA61_RS02205	COG2226	methyltransferase
FYA61_RS02250	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FYA61_RS02260	COG1028	Short-chain dehydrogenase reductase Sdr
FYA61_RS02280	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FYA61_RS02285	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FYA61_RS02295	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FYA61_RS02315	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FYA61_RS02320	COG1538	Outer membrane efflux protein
FYA61_RS02330	COG0351	phosphomethylpyrimidine kinase
FYA61_RS02335	COG2022	thiamine diphosphate biosynthetic process
FYA61_RS02340	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FYA61_RS02360	COG2226	methyltransferase
FYA61_RS02370	COG1194	a g-specific adenine glycosylase
FYA61_RS02380	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FYA61_RS02385	COG2177	Part of the ABC transporter FtsEX involved in
FYA61_RS02390	COG2884	Cell division ATP-binding protein ftsE
FYA61_RS02395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYA61_RS02400	COG4597	amino acid ABC transporter
FYA61_RS02405	COG0765	amino acid transport
FYA61_RS02410	COG1126	abc transporter atp-binding protein
FYA61_RS02440	COG0477	Major facilitator Superfamily
FYA61_RS02450	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FYA61_RS02455	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FYA61_RS02470	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FYA61_RS02475	COG0237	dephospho-CoA kinase activity
FYA61_RS02480	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
FYA61_RS02490	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FYA61_RS02505	COG3539	Fimbrial protein
FYA61_RS02510	COG3539	Fimbrial protein
FYA61_RS02525	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FYA61_RS02535	COG1846	Transcriptional regulator
FYA61_RS02605	COG1028	Short-chain dehydrogenase reductase Sdr
FYA61_RS02610	COG1024	Enoyl-CoA hydratase
FYA61_RS02615	COG1960	acyl-CoA dehydrogenase activity
FYA61_RS02645	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FYA61_RS02650	COG0352	thiamine-phosphate diphosphorylase activity
FYA61_RS02655	COG0351	phosphomethylpyrimidine kinase
FYA61_RS02665	COG1678	Uncharacterized ACR, COG1678
FYA61_RS02670	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FYA61_RS02695	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FYA61_RS02705	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FYA61_RS02710	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FYA61_RS02720	COG0557	exoribonuclease II activity
FYA61_RS02730	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FYA61_RS02735	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FYA61_RS02740	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FYA61_RS02750	COG0439	Biotin carboxylase
FYA61_RS02755	COG2264	protein methyltransferase activity
FYA61_RS02765	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FYA61_RS02790	COG1696	Membrane protein involved in D-alanine export
FYA61_RS02795	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FYA61_RS02840	COG1522	sequence-specific DNA binding
FYA61_RS02855	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FYA61_RS02920	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FYA61_RS02945	COG3028	Belongs to the UPF0307 family
FYA61_RS02950	COG0312	modulator of DNA gyrase
FYA61_RS02955	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FYA61_RS02960	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FYA61_RS02965	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FYA61_RS02975	COG0316	Belongs to the HesB IscA family
FYA61_RS02985	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FYA61_RS02995	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FYA61_RS03000	COG1881	PFAM PEBP family protein
FYA61_RS03005	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FYA61_RS03010	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FYA61_RS03025	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FYA61_RS03025	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FYA61_RS03040	COG2718	Belongs to the UPF0229 family
FYA61_RS03045	COG2719	SpoVR family
FYA61_RS03105	COG0165	Argininosuccinate lyase
FYA61_RS03110	COG0589	response to stress
FYA61_RS03120	COG2816	NAD+ diphosphatase activity
FYA61_RS03125	COG4993	Dehydrogenase
FYA61_RS03150	COG3181	Tripartite tricarboxylate transporter family receptor
FYA61_RS03155	COG2979	Protein of unknown function (DUF533)
FYA61_RS03160	COG4206	TonB-dependent receptor
FYA61_RS03175	COG0741	lytic transglycosylase activity
FYA61_RS03175	COG1388	LysM domain
FYA61_RS03180	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FYA61_RS03185	COG2226	methyltransferase
FYA61_RS03190	COG0328	RNA-DNA hybrid ribonuclease activity
FYA61_RS03215	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FYA61_RS03235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYA61_RS03240	COG1129	ABC transporter
FYA61_RS03240	COG0842	Transport permease protein
FYA61_RS03245	COG0842	Transport permease protein
FYA61_RS03265	COG0463	Glycosyl transferase, family 2
FYA61_RS03270	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FYA61_RS03285	COG1073	alpha beta
FYA61_RS03295	COG0697	spore germination
FYA61_RS03300	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FYA61_RS03325	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FYA61_RS03355	COG0823	Involved in the tonB-independent uptake of proteins
FYA61_RS03365	COG0848	biopolymer transport protein
FYA61_RS03370	COG0811	peptide transport
FYA61_RS03375	COG0824	Thioesterase
FYA61_RS03380	COG0442	prolyl-tRNA aminoacylation
FYA61_RS03425	COG2084	Dehydrogenase
FYA61_RS03470	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FYA61_RS03475	COG4654	Cytochrome c, class I
FYA61_RS03480	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FYA61_RS03545	COG1473	amidohydrolase
FYA61_RS03550	COG0418	dihydroorotase activity
FYA61_RS03555	COG0488	(ABC) transporter
FYA61_RS03565	COG2001	Belongs to the MraZ family
FYA61_RS03570	COG0275	rRNA processing
FYA61_RS03575	COG3116	cell division
FYA61_RS03585	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FYA61_RS03590	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FYA61_RS03595	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FYA61_RS03605	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FYA61_RS03610	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FYA61_RS03615	COG1181	Belongs to the D-alanine--D-alanine ligase family
FYA61_RS03620	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FYA61_RS03635	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FYA61_RS03650	COG0739	heme binding
FYA61_RS03655	COG0653	protein targeting
FYA61_RS03680	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FYA61_RS03685	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FYA61_RS03695	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FYA61_RS03755	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FYA61_RS03770	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
FYA61_RS03795	COG0583	DNA-binding transcription factor activity
FYA61_RS03805	COG3181	Tripartite tricarboxylate transporter family receptor
FYA61_RS03810	COG2084	Dehydrogenase
FYA61_RS03820	COG1597	lipid kinase activity
FYA61_RS03820	COG1803	Methylglyoxal synthase
FYA61_RS03830	COG0671	phosphoesterase, PA-phosphatase related
FYA61_RS03850	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FYA61_RS03855	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FYA61_RS03860	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FYA61_RS03865	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FYA61_RS03870	COG0649	NAD binding
FYA61_RS03875	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FYA61_RS03885	COG1034	ATP synthesis coupled electron transport
FYA61_RS03890	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FYA61_RS03895	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FYA61_RS03905	COG0713	ATP synthesis coupled electron transport
FYA61_RS03920	COG1007	ATP synthesis coupled electron transport
FYA61_RS03930	COG0560	Phosphoserine phosphatase
FYA61_RS03935	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FYA61_RS03940	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FYA61_RS03945	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FYA61_RS03960	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FYA61_RS03965	COG0450	alkyl hydroperoxide reductase
FYA61_RS03985	COG1214	PFAM Peptidase M22, glycoprotease
FYA61_RS03990	COG1573	uracil-dna glycosylase
FYA61_RS03995	COG0477	Major facilitator Superfamily
FYA61_RS04000	COG1196	nuclear chromosome segregation
FYA61_RS04010	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FYA61_RS04015	COG1126	abc transporter atp-binding protein
FYA61_RS04020	COG0765	amino acid transport
FYA61_RS04025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYA61_RS04030	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FYA61_RS04035	COG2917	probably involved in intracellular septation
FYA61_RS04040	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FYA61_RS04045	COG1122	ATPase activity
FYA61_RS04050	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FYA61_RS04085	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FYA61_RS04115	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FYA61_RS04120	COG2878	Part of a membrane complex involved in electron transport
FYA61_RS04140	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FYA61_RS04145	COG0251	oxidation-reduction process
FYA61_RS04155	COG3228	Belongs to the MtfA family
FYA61_RS04160	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FYA61_RS04170	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FYA61_RS04180	COG0159	tryptophan synthase activity
FYA61_RS04185	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FYA61_RS04190	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FYA61_RS04205	COG1530	ribonuclease E activity
FYA61_RS04210	COG0564	pseudouridine synthase activity
FYA61_RS04215	COG0546	phosphoglycolate phosphatase activity
FYA61_RS04220	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FYA61_RS04225	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FYA61_RS04230	COG3023	N-Acetylmuramoyl-L-alanine amidase
FYA61_RS04240	COG0424	maF-like protein
FYA61_RS04250	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FYA61_RS04260	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FYA61_RS04270	COG1028	Short-chain dehydrogenase reductase Sdr
FYA61_RS04275	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FYA61_RS04280	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FYA61_RS04305	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FYA61_RS04340	COG0481	GTPase activity
FYA61_RS04345	COG0681	Belongs to the peptidase S26 family
FYA61_RS04350	COG0571	ribonuclease III activity
FYA61_RS04355	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FYA61_RS04360	COG1381	Involved in DNA repair and RecF pathway recombination
FYA61_RS04380	COG0670	Belongs to the BI1 family
FYA61_RS04395	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FYA61_RS04420	COG0583	DNA-binding transcription factor activity
FYA61_RS04435	COG0791	NLP P60 protein
FYA61_RS04440	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FYA61_RS04445	COG3193	protein, possibly involved in utilization of glycolate and propanediol
FYA61_RS04455	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FYA61_RS04475	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FYA61_RS04510	COG1446	asparaginase
FYA61_RS04515	COG4172	Belongs to the ABC transporter superfamily
FYA61_RS04520	COG0747	negative chemotaxis
FYA61_RS04525	COG0601	transmembrane transport
FYA61_RS04550	COG0504	CTP synthase activity
FYA61_RS04560	COG0148	phosphopyruvate hydratase activity
FYA61_RS04575	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FYA61_RS04585	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FYA61_RS04590	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FYA61_RS04630	COG1981	membrane
FYA61_RS04650	COG0039	L-malate dehydrogenase activity
FYA61_RS04655	COG2188	Transcriptional regulator
FYA61_RS04660	COG2009	succinate dehydrogenase
FYA61_RS04665	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FYA61_RS04670	COG1053	succinate dehydrogenase
FYA61_RS04675	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FYA61_RS04680	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FYA61_RS04685	COG0372	Belongs to the citrate synthase family
FYA61_RS04695	COG0583	DNA-binding transcription factor activity
FYA61_RS04700	COG3842	ATPase activity
FYA61_RS04710	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FYA61_RS04715	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FYA61_RS04725	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FYA61_RS04735	COG3128	pkhd-type hydroxylase
FYA61_RS04740	COG4774	siderophore transport
FYA61_RS04755	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FYA61_RS04760	COG2894	cell division
FYA61_RS04765	COG0850	regulation of cytokinetic process
FYA61_RS04770	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FYA61_RS04780	COG1294	oxidase, subunit
FYA61_RS04800	COG0514	ATP-dependent DNA helicase (RecQ)
FYA61_RS04805	COG2255	four-way junction helicase activity
FYA61_RS04820	COG0632	four-way junction helicase activity
FYA61_RS04825	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FYA61_RS04855	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FYA61_RS04865	COG0006	proline dipeptidase activity
FYA61_RS04910	COG0429	hydrolase of the alpha beta-hydrolase fold
FYA61_RS04935	COG0513	Belongs to the DEAD box helicase family
FYA61_RS04955	COG1414	Transcriptional regulator
FYA61_RS05000	COG0167	dihydroorotate dehydrogenase activity
FYA61_RS05005	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FYA61_RS05010	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FYA61_RS05020	COG0583	DNA-binding transcription factor activity
FYA61_RS05050	COG0523	cobalamin synthesis protein
FYA61_RS05055	COG1335	isochorismatase
FYA61_RS05060	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FYA61_RS05065	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FYA61_RS05070	COG1802	Transcriptional regulator
FYA61_RS05075	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FYA61_RS05080	COG1028	Short-chain dehydrogenase reductase Sdr
FYA61_RS05095	COG3181	Tripartite tricarboxylate transporter family receptor
FYA61_RS05100	COG1280	lysine exporter protein (LysE YggA)
FYA61_RS05105	COG2828	Protein conserved in bacteria
FYA61_RS05150	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FYA61_RS05155	COG0735	belongs to the Fur family
FYA61_RS05185	COG0497	DNA recombination
FYA61_RS05190	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FYA61_RS05195	COG1420	regulation of RNA biosynthetic process
FYA61_RS05200	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FYA61_RS05210	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FYA61_RS05220	COG0443	Heat shock 70 kDa protein
FYA61_RS05230	COG0612	Peptidase, M16
FYA61_RS05250	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FYA61_RS05285	COG0745	RESPONSE REGULATOR receiver
FYA61_RS05295	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FYA61_RS05300	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FYA61_RS05305	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FYA61_RS05320	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FYA61_RS05335	COG1193	negative regulation of DNA recombination
FYA61_RS05340	COG0492	ferredoxin-NADP+ reductase activity
FYA61_RS05345	COG1674	ftsk spoiiie
FYA61_RS05350	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FYA61_RS05355	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FYA61_RS05360	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FYA61_RS05400	COG3468	outer membrane autotransporter barrel domain protein
FYA61_RS05420	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYA61_RS05425	COG1024	Enoyl-CoA hydratase
FYA61_RS05450	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FYA61_RS05455	COG0501	Belongs to the peptidase M48B family
FYA61_RS05465	COG0789	Transcriptional regulator
FYA61_RS05475	COG0165	Argininosuccinate lyase
FYA61_RS05480	COG0668	transmembrane transport
FYA61_RS05485	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FYA61_RS05485	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FYA61_RS05515	COG3321	synthase
FYA61_RS05515	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FYA61_RS05515	COG0604	alcohol dehydrogenase
FYA61_RS05515	COG4221	oxidoreductase activity
FYA61_RS05520	COG0149	triose-phosphate isomerase activity
FYA61_RS05530	COG0438	transferase activity, transferring glycosyl groups
FYA61_RS05535	COG4607	ABC-type enterochelin transport system periplasmic component
FYA61_RS05540	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FYA61_RS05545	COG4605	iron ion homeostasis
FYA61_RS05550	COG4604	ABC transporter, ATP-binding protein
FYA61_RS05570	COG0179	Fumarylacetoacetate (FAA) hydrolase
FYA61_RS05585	COG1028	Short-chain dehydrogenase reductase Sdr
FYA61_RS05620	COG1595	DNA-templated transcription, initiation
FYA61_RS05645	COG2186	Transcriptional regulator
FYA61_RS05650	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYA61_RS05655	COG1960	acyl-CoA dehydrogenase activity
FYA61_RS05675	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
FYA61_RS05680	COG2199	diguanylate cyclase activity
FYA61_RS05680	COG2202	Pas domain
FYA61_RS05680	COG2200	EAL domain
FYA61_RS05755	COG2271	Major facilitator Superfamily
FYA61_RS05770	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FYA61_RS05780	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FYA61_RS05800	COG2321	neutral zinc metallopeptidase
FYA61_RS05805	COG0009	L-threonylcarbamoyladenylate synthase
FYA61_RS05810	COG1994	Peptidase M50
FYA61_RS05815	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FYA61_RS05820	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
FYA61_RS05830	COG2850	peptidyl-arginine hydroxylation
FYA61_RS05835	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FYA61_RS05855	COG3360	Dodecin
FYA61_RS05875	COG1802	Transcriptional regulator
FYA61_RS05890	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FYA61_RS05900	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FYA61_RS05925	COG0668	transmembrane transport
FYA61_RS05945	COG0483	inositol monophosphate 1-phosphatase activity
FYA61_RS05950	COG1253	flavin adenine dinucleotide binding
FYA61_RS05955	COG1968	undecaprenyl-diphosphatase activity
FYA61_RS05960	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FYA61_RS05965	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FYA61_RS05975	COG0215	cysteine-tRNA ligase activity
FYA61_RS05985	COG0825	malonyl-CoA metabolic process
FYA61_RS05990	COG0037	tRNA processing
FYA61_RS06010	COG2814	Major facilitator Superfamily
FYA61_RS06015	COG4772	TonB-dependent receptor
FYA61_RS06025	COG4993	Dehydrogenase
FYA61_RS06040	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FYA61_RS06045	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FYA61_RS06050	COG1121	(ABC) transporter
FYA61_RS06055	COG0803	Belongs to the bacterial solute-binding protein 9 family
FYA61_RS06070	COG0500	methyltransferase
FYA61_RS06095	COG2204	response regulator
FYA61_RS06100	COG4191	Histidine kinase
FYA61_RS06110	COG0424	maF-like protein
FYA61_RS06115	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FYA61_RS06120	COG0799	negative regulation of ribosome biogenesis
FYA61_RS06125	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FYA61_RS06135	COG0151	Belongs to the GarS family
FYA61_RS06140	COG0217	transcriptional regulatory protein
FYA61_RS06145	COG0433	COG0433 Predicted ATPase
FYA61_RS06155	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FYA61_RS06160	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FYA61_RS06185	COG2814	Major facilitator Superfamily
FYA61_RS06190	COG1566	PFAM secretion protein HlyD family protein
FYA61_RS06200	COG1846	Transcriptional regulator
FYA61_RS06250	COG1530	ribonuclease E activity
FYA61_RS06310	COG2433	Pfam Transposase IS66
FYA61_RS06340	COG1278	Cold shock
FYA61_RS06350	COG2801	Transposase and inactivated derivatives
FYA61_RS06395	COG0544	peptidyl-prolyl cis-trans isomerase activity
FYA61_RS06400	COG0740	serine-type endopeptidase activity
FYA61_RS06410	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FYA61_RS06425	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FYA61_RS06465	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FYA61_RS06485	COG0583	DNA-binding transcription factor activity
FYA61_RS06500	COG0556	nucleotide-excision repair
FYA61_RS06505	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FYA61_RS06515	COG1104	cysteine desulfurase activity
FYA61_RS06520	COG0822	iron-sulfur transferase activity
FYA61_RS06525	COG0316	Belongs to the HesB IscA family
FYA61_RS06530	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FYA61_RS06535	COG0443	Heat shock 70 kDa protein
FYA61_RS06540	COG0633	Ferredoxin
FYA61_RS06545	COG2975	iron-sulfur cluster assembly
FYA61_RS06570	COG2801	Transposase and inactivated derivatives
FYA61_RS06575	COG2801	Transposase and inactivated derivatives
FYA61_RS06595	COG1803	Methylglyoxal synthase
FYA61_RS06605	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FYA61_RS06610	COG1028	Short-chain dehydrogenase reductase Sdr
FYA61_RS06620	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FYA61_RS06635	COG1136	(ABC) transporter
FYA61_RS06640	COG0084	hydrolase, TatD family'
FYA61_RS06650	COG3712	iron ion homeostasis
FYA61_RS06655	COG1595	DNA-templated transcription, initiation
FYA61_RS06685	COG3181	Tripartite tricarboxylate transporter family receptor
FYA61_RS06695	COG3181	Tripartite tricarboxylate transporter family receptor
FYA61_RS06705	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FYA61_RS06725	COG0583	DNA-binding transcription factor activity
FYA61_RS06735	COG1012	belongs to the aldehyde dehydrogenase family
FYA61_RS06795	COG0613	PHP domain protein
FYA61_RS06805	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FYA61_RS06810	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FYA61_RS06810	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FYA61_RS06830	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FYA61_RS06835	COG0047	phosphoribosylformylglycinamidine synthase activity
FYA61_RS06835	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FYA61_RS06875	COG0747	negative chemotaxis
FYA61_RS06880	COG4608	Belongs to the ABC transporter superfamily
FYA61_RS06890	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FYA61_RS06910	COG0601	transmembrane transport
FYA61_RS06915	COG2072	flavoprotein involved in K transport
FYA61_RS06930	COG1695	Transcriptional regulator
FYA61_RS06945	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FYA61_RS06945	COG0519	Catalyzes the synthesis of GMP from XMP
FYA61_RS06955	COG3177	Filamentation induced by cAMP protein fic
FYA61_RS06990	COG1733	regulation of RNA biosynthetic process
FYA61_RS06995	COG0384	phenazine biosynthesis protein PhzF
FYA61_RS07020	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FYA61_RS07045	COG0583	DNA-binding transcription factor activity
FYA61_RS07080	COG1012	belongs to the aldehyde dehydrogenase family
FYA61_RS07095	COG2814	Major facilitator Superfamily
FYA61_RS07100	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FYA61_RS07105	COG2207	Transcriptional regulator
FYA61_RS07110	COG2807	transmembrane transport
FYA61_RS07135	COG2814	Major facilitator Superfamily
FYA61_RS07140	COG0583	DNA-binding transcription factor activity
FYA61_RS07165	COG1396	sequence-specific DNA binding
FYA61_RS07200	COG5507	3-demethylubiquinone-9 3-methyltransferase
FYA61_RS07225	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FYA61_RS07280	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
FYA61_RS07285	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FYA61_RS07290	COG0390	transport system, permease component
FYA61_RS07300	COG0587	DNA-directed DNA polymerase activity
FYA61_RS07335	COG0720	synthase
FYA61_RS07340	COG0602	queuosine metabolic process
FYA61_RS07375	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FYA61_RS07385	COG0842	Transport permease protein
FYA61_RS07390	COG1131	(ABC) transporter
FYA61_RS07400	COG1309	transcriptional regulator
FYA61_RS07405	COG2130	NADP-dependent
FYA61_RS07415	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FYA61_RS07425	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FYA61_RS07460	COG0420	3'-5' exonuclease activity
FYA61_RS07485	COG3181	Tripartite tricarboxylate transporter family receptor
FYA61_RS07490	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FYA61_RS07490	COG2111	Na H antiporter
FYA61_RS07495	COG1006	Multisubunit Na H antiporter MnhC subunit
FYA61_RS07500	COG0651	ATP synthesis coupled electron transport
FYA61_RS07505	COG1863	multisubunit Na H antiporter MnhE subunit
FYA61_RS07510	COG2212	antiporter activity
FYA61_RS07515	COG1320	monovalent cation:proton antiporter activity
FYA61_RS07530	COG0590	tRNA wobble adenosine to inosine editing
FYA61_RS07535	COG1619	proteins homologs of microcin C7 resistance protein MccF
FYA61_RS07540	COG0488	(ABC) transporter
FYA61_RS07575	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FYA61_RS07580	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FYA61_RS07585	COG2252	PERMEase
FYA61_RS07590	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FYA61_RS07595	COG0583	DNA-binding transcription factor activity
FYA61_RS07620	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FYA61_RS07630	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FYA61_RS07665	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FYA61_RS07670	COG0789	Transcriptional regulator
FYA61_RS07675	COG2217	Heavy metal translocating P-type atpase
FYA61_RS07685	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FYA61_RS07685	COG0678	peroxiredoxin activity
FYA61_RS07695	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FYA61_RS07700	COG0584	glycerophosphoryl diester phosphodiesterase
FYA61_RS07705	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FYA61_RS07715	COG4181	ATPase activity
FYA61_RS07725	COG3210	domain, Protein
FYA61_RS07725	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
FYA61_RS07725	COG3064	Membrane
FYA61_RS07740	COG3121	Chaperone
FYA61_RS07745	COG3188	usher protein
FYA61_RS07755	COG2831	hemolysin activation secretion protein
FYA61_RS07765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYA61_RS07770	COG0765	amino acid transport
FYA61_RS07775	COG1126	abc transporter atp-binding protein
FYA61_RS07780	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FYA61_RS07785	COG1758	RNA polymerase activity
FYA61_RS07790	COG0194	GDP metabolic process
FYA61_RS07795	COG1028	Short-chain dehydrogenase reductase Sdr
FYA61_RS07800	COG0791	NLP P60 protein
FYA61_RS07805	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FYA61_RS07815	COG1561	YicC-like family, N-terminal region
FYA61_RS07820	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FYA61_RS07830	COG2079	MmgE PrpD family protein
FYA61_RS07835	COG1960	acyl-CoA dehydrogenase activity
FYA61_RS07840	COG0583	DNA-binding transcription factor activity
FYA61_RS07850	COG0840	transmembrane signaling receptor activity
FYA61_RS07860	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FYA61_RS07865	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FYA61_RS07870	COG0174	glutamine synthetase
FYA61_RS07885	COG0583	DNA-binding transcription factor activity
FYA61_RS07890	COG1741	Belongs to the pirin family
FYA61_RS07895	COG1741	Belongs to the pirin family
FYA61_RS07900	COG3842	ATPase activity
FYA61_RS07910	COG1840	ABC-type Fe3 transport system, periplasmic component
FYA61_RS07940	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FYA61_RS07945	COG0583	DNA-binding transcription factor activity
FYA61_RS07950	COG0783	Belongs to the Dps family
FYA61_RS07965	COG0463	Glycosyl transferase, family 2
FYA61_RS07990	COG0438	transferase activity, transferring glycosyl groups
FYA61_RS08005	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FYA61_RS08030	COG3842	ATPase activity
FYA61_RS08035	COG0395	ABC-type sugar transport system, permease component
FYA61_RS08040	COG1175	transmembrane transport
FYA61_RS08055	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FYA61_RS08065	COG0559	Belongs to the binding-protein-dependent transport system permease family
FYA61_RS08085	COG1794	racemase activity, acting on amino acids and derivatives
FYA61_RS08095	COG0625	glutathione transferase activity
FYA61_RS08100	COG2133	pyrroloquinoline quinone binding
FYA61_RS08105	COG0697	spore germination
FYA61_RS08125	COG1464	Belongs to the NlpA lipoprotein family
FYA61_RS08130	COG1304	FMN binding
FYA61_RS08135	COG0688	phosphatidylethanolamine metabolic process
FYA61_RS08145	COG1012	belongs to the aldehyde dehydrogenase family
FYA61_RS08155	COG0028	Belongs to the TPP enzyme family
FYA61_RS08165	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FYA61_RS08165	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FYA61_RS08175	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FYA61_RS08185	COG3189	MarR family transcriptional regulator
FYA61_RS08190	COG2985	domain, Protein
FYA61_RS08195	COG0076	glutamate decarboxylase activity
FYA61_RS08220	COG2205	protein histidine kinase activity
FYA61_RS08220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYA61_RS08225	COG2197	response regulator
FYA61_RS08230	COG5001	Diguanylate cyclase
FYA61_RS08230	COG4251	negative regulation of phosphorylation
FYA61_RS08230	COG3706	GGDEF domain
FYA61_RS08230	COG2203	Gaf domain
FYA61_RS08235	COG1253	flavin adenine dinucleotide binding
FYA61_RS08255	COG2200	EAL domain
FYA61_RS08300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYA61_RS08305	COG0765	amino acid transport
FYA61_RS08310	COG1126	abc transporter atp-binding protein
FYA61_RS08335	COG1619	proteins homologs of microcin C7 resistance protein MccF
FYA61_RS08345	COG2203	Gaf domain
FYA61_RS08345	COG2199	diguanylate cyclase activity
FYA61_RS08380	COG1191	sigma factor activity
FYA61_RS08400	COG0840	transmembrane signaling receptor activity
FYA61_RS08405	COG0840	transmembrane signaling receptor activity
FYA61_RS08430	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FYA61_RS08440	COG1580	Controls the rotational direction of flagella during chemotaxis
FYA61_RS08460	COG1317	bacterial-type flagellum organization
FYA61_RS08465	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FYA61_RS08475	COG1677	Flagellar hook-basal body complex protein FliE
FYA61_RS08485	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FYA61_RS08525	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYA61_RS08530	COG3181	Tripartite tricarboxylate transporter family receptor
FYA61_RS08540	COG0285	dihydrofolate synthase activity
FYA61_RS08550	COG1286	toxin biosynthetic process
FYA61_RS08570	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FYA61_RS08575	COG0024	Methionine aminopeptidase
FYA61_RS08580	COG0052	Belongs to the universal ribosomal protein uS2 family
FYA61_RS08585	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FYA61_RS08590	COG0528	UMP kinase activity
FYA61_RS08595	COG0233	cytoplasmic translational termination
FYA61_RS08600	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FYA61_RS08610	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FYA61_RS08615	COG0750	zinc metalloprotease
FYA61_RS08620	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FYA61_RS08630	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FYA61_RS08635	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FYA61_RS08645	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FYA61_RS08650	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FYA61_RS08655	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FYA61_RS08665	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FYA61_RS08675	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FYA61_RS08675	COG0519	Catalyzes the synthesis of GMP from XMP
FYA61_RS08710	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FYA61_RS08720	COG2914	Belongs to the UPF0125 (RnfH) family
FYA61_RS08730	COG1960	acyl-CoA dehydrogenase activity
FYA61_RS08735	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FYA61_RS08760	COG0583	DNA-binding transcription factor activity
FYA61_RS08765	COG2175	clavaminate synthase activity
FYA61_RS08775	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FYA61_RS08780	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FYA61_RS08790	COG0084	hydrolase, TatD family'
FYA61_RS08805	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYA61_RS08810	COG0765	amino acid transport
FYA61_RS08820	COG0010	Belongs to the arginase family
FYA61_RS08830	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FYA61_RS08840	COG0095	Lipoate-protein ligase
FYA61_RS08855	COG0386	Belongs to the glutathione peroxidase family
FYA61_RS08875	COG0415	Belongs to the DNA photolyase family
FYA61_RS08905	COG2259	Doxx family
FYA61_RS08915	COG1028	Short-chain dehydrogenase reductase Sdr
FYA61_RS08925	COG0842	Transport permease protein
FYA61_RS08930	COG0842	Transport permease protein
FYA61_RS08930	COG1129	ABC transporter
FYA61_RS08935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYA61_RS08955	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FYA61_RS08980	COG2733	membrane
FYA61_RS09015	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FYA61_RS09045	COG2814	Major facilitator Superfamily
FYA61_RS09075	COG3486	L-lysine 6-monooxygenase (NADPH) activity
FYA61_RS09090	COG1028	Short-chain dehydrogenase reductase Sdr
FYA61_RS09100	COG3022	response to hydroperoxide
FYA61_RS09125	COG0028	Belongs to the TPP enzyme family
FYA61_RS09130	COG0440	acetolactate synthase activity
FYA61_RS09140	COG1183	phosphatidylcholine synthase activity
FYA61_RS09155	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FYA61_RS09160	COG1185	polyribonucleotide nucleotidyltransferase activity
FYA61_RS09190	COG0583	DNA-binding transcription factor activity
FYA61_RS09205	COG1129	ABC transporter
FYA61_RS09245	COG1280	lysine exporter protein (LysE YggA)
FYA61_RS09260	COG3161	chorismate lyase activity
FYA61_RS09265	COG1187	pseudouridine synthase activity
FYA61_RS09270	COG0583	DNA-binding transcription factor activity
FYA61_RS09275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYA61_RS09295	COG1999	signal sequence binding
FYA61_RS09315	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FYA61_RS09320	COG4566	intracellular signal transduction
FYA61_RS09330	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FYA61_RS09335	COG0508	dehydrogenase complex catalyzes the overall conversion of
FYA61_RS09340	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FYA61_RS09355	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FYA61_RS09360	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FYA61_RS09370	COG1028	Short-chain dehydrogenase reductase Sdr
FYA61_RS09375	COG0583	DNA-binding transcription factor activity
FYA61_RS09380	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FYA61_RS09405	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FYA61_RS09425	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FYA61_RS09440	COG2900	Belongs to the SlyX family
FYA61_RS09445	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FYA61_RS09470	COG2814	Major facilitator Superfamily
FYA61_RS09510	COG2801	Transposase and inactivated derivatives
FYA61_RS09565	COG2171	N-acyltransferase activity
FYA61_RS09570	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FYA61_RS09575	COG2890	protein-(glutamine-N5) methyltransferase activity
FYA61_RS09580	COG0488	(ABC) transporter
FYA61_RS09585	COG4771	TonB-dependent receptor
FYA61_RS09590	COG0210	DNA helicase
FYA61_RS09620	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FYA61_RS09620	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FYA61_RS09630	COG0196	riboflavin kinase activity
FYA61_RS09635	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FYA61_RS09640	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FYA61_RS09645	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FYA61_RS09665	COG1522	sequence-specific DNA binding
FYA61_RS09695	COG0756	dUTP diphosphatase activity
FYA61_RS09705	COG0765	amino acid transport
FYA61_RS09710	COG0765	amino acid transport
FYA61_RS09715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYA61_RS09730	COG1764	response to oxidative stress
FYA61_RS09740	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FYA61_RS09745	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FYA61_RS09760	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FYA61_RS09765	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FYA61_RS09770	COG2197	response regulator
FYA61_RS09775	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FYA61_RS09815	COG2801	Transposase and inactivated derivatives
FYA61_RS09820	COG2801	Transposase and inactivated derivatives
FYA61_RS09840	COG0135	phosphoribosylanthranilate isomerase activity
FYA61_RS09845	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FYA61_RS09850	COG0101	tRNA pseudouridine synthase activity
FYA61_RS09860	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FYA61_RS09865	COG0473	3-isopropylmalate dehydrogenase activity
FYA61_RS09875	COG0066	3-isopropylmalate dehydratase activity
FYA61_RS09900	COG2197	response regulator
FYA61_RS09905	COG0501	Belongs to the peptidase M48B family
FYA61_RS09910	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FYA61_RS09930	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FYA61_RS09940	COG1295	ribonuclease BN
FYA61_RS09950	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FYA61_RS10000	COG1450	Type ii and iii secretion system protein
FYA61_RS10045	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FYA61_RS10085	COG0181	hydroxymethylbilane synthase activity
FYA61_RS10090	COG0861	Integral membrane protein TerC family
FYA61_RS10095	COG0861	Integral membrane protein TerC family
FYA61_RS10100	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FYA61_RS10105	COG0045	succinate-CoA ligase (ADP-forming) activity
FYA61_RS10125	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FYA61_RS10135	COG2137	regulation of response to DNA damage stimulus
FYA61_RS10140	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FYA61_RS10165	COG2974	May be involved in recombination
FYA61_RS10170	COG0540	Belongs to the ATCase OTCase family
FYA61_RS10200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FYA61_RS10260	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FYA61_RS10280	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FYA61_RS10295	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FYA61_RS10305	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FYA61_RS10310	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FYA61_RS10320	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FYA61_RS10330	COG3620	sequence-specific DNA binding
FYA61_RS10335	COG2233	PERMEase
FYA61_RS10365	COG0406	alpha-ribazole phosphatase activity
FYA61_RS10370	COG1028	Short-chain dehydrogenase reductase Sdr
FYA61_RS10380	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FYA61_RS10385	COG0505	Belongs to the CarA family
FYA61_RS10390	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FYA61_RS10395	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FYA61_RS10415	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FYA61_RS10420	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FYA61_RS10425	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FYA61_RS10455	COG1686	Belongs to the peptidase S11 family
FYA61_RS10460	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FYA61_RS10465	COG4974	Belongs to the 'phage' integrase family
FYA61_RS10470	COG0583	DNA-binding transcription factor activity
FYA61_RS10475	COG0028	Belongs to the TPP enzyme family
FYA61_RS10480	COG1960	acyl-CoA dehydrogenase activity
FYA61_RS10510	COG4771	TonB-dependent receptor
FYA61_RS10520	COG0009	L-threonylcarbamoyladenylate synthase
FYA61_RS10525	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FYA61_RS10530	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FYA61_RS10535	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FYA61_RS10545	COG1301	dicarboxylic acid transport
FYA61_RS10550	COG0456	acetyltransferase
FYA61_RS10590	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FYA61_RS10600	COG0739	heme binding
FYA61_RS10610	COG0521	Mo-molybdopterin cofactor biosynthetic process
FYA61_RS10615	COG0306	phosphate transporter
FYA61_RS10630	COG0789	Transcriptional regulator
FYA61_RS10650	COG0625	glutathione transferase activity
FYA61_RS10665	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FYA61_RS10685	COG0126	phosphoglycerate kinase activity
FYA61_RS10690	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FYA61_RS10695	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FYA61_RS10700	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FYA61_RS10715	COG0281	malic enzyme
FYA61_RS10715	COG0280	phosphate acetyltransferase
FYA61_RS10725	COG0436	Aminotransferase
FYA61_RS10730	COG0741	lytic transglycosylase activity
FYA61_RS10735	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FYA61_RS10760	COG4575	ribosome binding
FYA61_RS10770	COG1648	precorrin-2 dehydrogenase activity
FYA61_RS10770	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FYA61_RS10775	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FYA61_RS10780	COG2027	D-alanyl-D-alanine carboxypeptidase
FYA61_RS10785	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FYA61_RS10790	COG0343	queuine tRNA-ribosyltransferase activity
FYA61_RS10795	COG1862	Preprotein translocase
FYA61_RS10800	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FYA61_RS10805	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FYA61_RS10825	COG0667	Aldo Keto reductase
FYA61_RS10830	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FYA61_RS10835	COG4535	Mg2 and Co2 transporter CorC
FYA61_RS10840	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FYA61_RS10845	COG1702	phosphate starvation-inducible protein PhoH
FYA61_RS10850	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FYA61_RS10875	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FYA61_RS10880	COG0697	spore germination
FYA61_RS10890	COG0494	nUDIX hydrolase
FYA61_RS10905	COG3530	Putative quorum-sensing-regulated virulence factor
FYA61_RS10915	COG3015	lipoprotein NlpE involved in copper resistance
FYA61_RS10935	COG2814	Major facilitator Superfamily
FYA61_RS10945	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
FYA61_RS10970	COG0628	permease
FYA61_RS10980	COG1131	(ABC) transporter
FYA61_RS10985	COG1764	response to oxidative stress
FYA61_RS10990	COG1846	Transcriptional regulator
FYA61_RS10995	COG2224	Isocitrate lyase
FYA61_RS11000	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FYA61_RS11000	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FYA61_RS11010	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FYA61_RS11015	COG0322	excinuclease ABC activity
FYA61_RS11020	COG1472	Belongs to the glycosyl hydrolase 3 family
FYA61_RS11025	COG0736	holo-[acyl-carrier-protein] synthase activity
FYA61_RS11030	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FYA61_RS11040	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FYA61_RS11045	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYA61_RS11050	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYA61_RS11080	COG4149	molybdate abc transporter
FYA61_RS11085	COG0725	ABC transporter, periplasmic molybdate-binding protein
FYA61_RS11090	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FYA61_RS11095	COG4120	Belongs to the binding-protein-dependent transport system permease family
FYA61_RS11110	COG2032	superoxide dismutase activity
FYA61_RS11120	COG0318	PFAM AMP-dependent synthetase and ligase
FYA61_RS11125	COG1024	Enoyl-CoA hydratase
FYA61_RS11135	COG1802	Transcriptional regulator
FYA61_RS11150	COG1217	gtp-binding protein TYPA
FYA61_RS11155	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FYA61_RS11160	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FYA61_RS11165	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FYA61_RS11170	COG0195	Participates in both transcription termination and antitermination
FYA61_RS11170	COG2251	uridine kinase activity
FYA61_RS11175	COG0779	Required for maturation of 30S ribosomal subunits
FYA61_RS11180	COG1187	pseudouridine synthase activity
FYA61_RS11185	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FYA61_RS11195	COG0583	DNA-binding transcription factor activity
FYA61_RS11205	COG0523	cobalamin synthesis protein
FYA61_RS11225	COG0625	glutathione transferase activity
FYA61_RS11230	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FYA61_RS11240	COG2003	Belongs to the UPF0758 family
FYA61_RS11245	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FYA61_RS11250	COG3483	tryptophan 2,3-dioxygenase activity
FYA61_RS11255	COG0254	rRNA binding
FYA61_RS11295	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FYA61_RS11300	COG1562	ergosterol biosynthetic process
FYA61_RS11305	COG1562	ergosterol biosynthetic process
FYA61_RS11310	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
FYA61_RS11310	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
FYA61_RS11315	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FYA61_RS11340	COG1477	protein flavinylation
FYA61_RS11355	COG0542	response to heat
FYA61_RS11365	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FYA61_RS11380	COG0678	peroxiredoxin activity
FYA61_RS11390	COG0412	Dienelactone hydrolase
FYA61_RS11395	COG0315	cyclic pyranopterin monophosphate synthase activity
FYA61_RS11405	COG0314	molybdopterin synthase activity
FYA61_RS11410	COG0521	Mo-molybdopterin cofactor biosynthetic process
FYA61_RS11415	COG0303	'Molybdopterin
FYA61_RS11420	COG0746	molybdenum cofactor guanylyltransferase activity
FYA61_RS11425	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FYA61_RS11460	COG2264	protein methyltransferase activity
FYA61_RS11485	COG5006	permease, DMT superfamily
FYA61_RS11490	COG1028	Short-chain dehydrogenase reductase Sdr
FYA61_RS11515	COG1666	GTP binding
FYA61_RS11560	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FYA61_RS11565	COG1845	cytochrome c oxidase, subunit III
FYA61_RS11570	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FYA61_RS11580	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
FYA61_RS11600	COG0783	Belongs to the Dps family
FYA61_RS11605	COG1028	Short-chain dehydrogenase reductase Sdr
FYA61_RS11615	COG1346	cytolysis
FYA61_RS11635	COG4172	Belongs to the ABC transporter superfamily
FYA61_RS11640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FYA61_RS11645	COG0601	transmembrane transport
FYA61_RS11650	COG0747	negative chemotaxis
FYA61_RS11660	COG0598	Magnesium transport protein CorA
FYA61_RS11665	COG0210	DNA helicase
FYA61_RS11680	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FYA61_RS11685	COG1012	belongs to the aldehyde dehydrogenase family
FYA61_RS11690	COG0483	inositol monophosphate 1-phosphatase activity
FYA61_RS11695	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FYA61_RS11705	COG1045	serine acetyltransferase
FYA61_RS11715	COG1960	acyl-CoA dehydrogenase activity
FYA61_RS11720	COG0183	Belongs to the thiolase family
FYA61_RS11725	COG1250	3-hydroxyacyl-CoA dehydrogenase
FYA61_RS11725	COG1024	Enoyl-CoA hydratase
FYA61_RS11735	COG1024	Enoyl-CoA hydratase
FYA61_RS11735	COG1250	3-hydroxyacyl-CoA dehydrogenase
FYA61_RS11740	COG0183	Belongs to the thiolase family
FYA61_RS11755	COG0318	PFAM AMP-dependent synthetase and ligase
FYA61_RS11775	COG3246	L-lysine catabolic process to acetate
FYA61_RS11780	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FYA61_RS11795	COG1610	YqeY-like protein
FYA61_RS11840	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FYA61_RS11855	COG0667	Aldo Keto reductase
FYA61_RS11860	COG0656	L-ascorbic acid biosynthetic process
FYA61_RS11880	COG5265	(ABC) transporter
FYA61_RS11930	COG1522	sequence-specific DNA binding
FYA61_RS11950	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FYA61_RS11960	COG1278	Cold shock
FYA61_RS11980	COG3181	Tripartite tricarboxylate transporter family receptor
FYA61_RS11985	COG1802	Transcriptional regulator
FYA61_RS12015	COG0776	regulation of translation
FYA61_RS12020	COG0072	phenylalanine-tRNA ligase activity
FYA61_RS12020	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FYA61_RS12025	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FYA61_RS12030	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FYA61_RS12035	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FYA61_RS12080	COG0347	Belongs to the P(II) protein family
FYA61_RS12085	COG0004	ammonium transporteR
FYA61_RS12115	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FYA61_RS12115	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FYA61_RS12115	COG0506	proline dehydrogenase activity
FYA61_RS12125	COG3008	intermembrane lipid transfer
FYA61_RS12140	COG4953	penicillin-binding protein 1C
FYA61_RS12150	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FYA61_RS12155	COG1278	Cold shock
FYA61_RS12165	COG0183	Belongs to the thiolase family
FYA61_RS12170	COG0038	chloride channel
FYA61_RS12180	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FYA61_RS12185	COG1570	exodeoxyribonuclease VII activity
FYA61_RS12190	COG0811	peptide transport
FYA61_RS12195	COG0848	biopolymer transport protein
FYA61_RS12200	COG1663	tetraacyldisaccharide 4'-kinase activity
FYA61_RS12205	COG2835	tetraacyldisaccharide 4'-kinase activity
FYA61_RS12210	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FYA61_RS12215	COG0563	adenylate kinase activity
FYA61_RS12225	COG0728	peptidoglycan biosynthetic process
FYA61_RS12270	COG0268	Binds directly to 16S ribosomal RNA
FYA61_RS12275	COG3836	Belongs to the HpcH HpaI aldolase family
FYA61_RS12305	COG2186	Transcriptional regulator
FYA61_RS12320	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FYA61_RS12330	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FYA61_RS12335	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FYA61_RS12340	COG0137	argininosuccinate synthase activity
FYA61_RS12365	COG3158	transport of potassium into the cell
FYA61_RS12370	COG0642	Histidine kinase
FYA61_RS12400	COG0776	regulation of translation
FYA61_RS12405	COG2873	o-acetylhomoserine
FYA61_RS12410	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FYA61_RS12415	COG0557	exoribonuclease II activity
FYA61_RS12435	COG2153	protein acetylation
FYA61_RS12440	COG0679	Auxin Efflux Carrier
FYA61_RS12445	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FYA61_RS12450	COG2391	methyltransferase activity
FYA61_RS12455	COG0069	glutamate synthase activity
FYA61_RS12480	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
FYA61_RS12500	COG2826	transposase and inactivated derivatives, IS30 family
FYA61_RS12515	COG3706	GGDEF domain
FYA61_RS12550	COG3909	cytochrome
FYA61_RS12555	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FYA61_RS12560	COG0625	glutathione transferase activity
FYA61_RS12565	COG0730	response to heat
FYA61_RS12570	COG0482	sulfurtransferase activity
FYA61_RS12575	COG0583	DNA-binding transcription factor activity
FYA61_RS12615	COG0247	lactate metabolic process
FYA61_RS12620	COG0277	FAD linked oxidase domain protein
FYA61_RS12625	COG0277	FAD linked oxidase domain protein
FYA61_RS12645	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FYA61_RS12650	COG0312	modulator of DNA gyrase
FYA61_RS12665	COG0308	aminopeptidase N
FYA61_RS12670	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FYA61_RS12695	COG0436	Aminotransferase
FYA61_RS12700	COG3737	Protein of unknown function (DUF498/DUF598)
FYA61_RS12705	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FYA61_RS12710	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FYA61_RS12715	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FYA61_RS12725	COG0305	Participates in initiation and elongation during chromosome replication
FYA61_RS12735	COG0359	binds to the 23S rRNA
FYA61_RS12740	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FYA61_RS12745	COG2965	DNA replication, synthesis of RNA primer
FYA61_RS12750	COG0360	Binds together with S18 to 16S ribosomal RNA
FYA61_RS12755	COG1469	GTP cyclohydrolase I activity
FYA61_RS12760	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FYA61_RS12765	COG0142	geranyltranstransferase activity
FYA61_RS12770	COG1722	exodeoxyribonuclease VII activity
FYA61_RS12815	COG0501	Belongs to the peptidase M48B family
FYA61_RS12835	COG1132	(ABC) transporter
FYA61_RS12870	COG0463	Glycosyl transferase, family 2
FYA61_RS12875	COG0726	polysaccharide deacetylase
FYA61_RS12880	COG0438	transferase activity, transferring glycosyl groups
FYA61_RS12895	COG1643	Atp-dependent helicase
FYA61_RS12900	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FYA61_RS12900	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FYA61_RS12905	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FYA61_RS12910	COG0704	Plays a role in the regulation of phosphate uptake
FYA61_RS12915	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FYA61_RS12925	COG1322	Protein conserved in bacteria
FYA61_RS12945	COG1177	transmembrane transport
FYA61_RS12950	COG1176	ABC-type spermidine putrescine transport system, permease component I
FYA61_RS12955	COG3842	ATPase activity
FYA61_RS12965	COG3642	lipopolysaccharide core region biosynthetic process
FYA61_RS12970	COG2346	COG2346, Truncated hemoglobins
FYA61_RS12975	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FYA61_RS12980	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FYA61_RS12990	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FYA61_RS12990	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FYA61_RS13020	COG2050	protein possibly involved in aromatic compounds catabolism
FYA61_RS13025	COG1024	Enoyl-CoA hydratase
FYA61_RS13030	COG1012	belongs to the aldehyde dehydrogenase family
FYA61_RS13035	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FYA61_RS13040	COG2151	metal-sulfur cluster biosynthetic enzyme
FYA61_RS13045	COG3396	Phenylacetate-CoA oxygenase
FYA61_RS13050	COG3460	Phenylacetate-CoA oxygenase
FYA61_RS13055	COG3396	Phenylacetate-CoA oxygenase
FYA61_RS13060	COG3327	negative regulation of DNA-templated transcription, initiation
FYA61_RS13065	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FYA61_RS13070	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FYA61_RS13075	COG0501	Belongs to the peptidase M48B family
FYA61_RS13080	COG1162	GTPase activity
FYA61_RS13085	COG3622	Belongs to the hyi family
FYA61_RS13100	COG0335	large ribosomal subunit rRNA binding
FYA61_RS13130	COG0175	sulfate reduction
FYA61_RS13135	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FYA61_RS13140	COG4208	sulfate ABC transporter
FYA61_RS13145	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FYA61_RS13150	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FYA61_RS13155	COG0450	alkyl hydroperoxide reductase
FYA61_RS13160	COG1960	acyl-CoA dehydrogenase activity
FYA61_RS13165	COG2985	domain, Protein
FYA61_RS13180	COG0123	including yeast histone deacetylase and acetoin utilization protein
FYA61_RS13185	COG2951	lytic endotransglycosylase activity
FYA61_RS13195	COG0587	DNA-directed DNA polymerase activity
FYA61_RS13200	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FYA61_RS13205	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FYA61_RS13210	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FYA61_RS13230	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FYA61_RS13235	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FYA61_RS13245	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FYA61_RS13250	COG1605	Chorismate mutase
FYA61_RS13250	COG0077	Prephenate dehydratase
FYA61_RS13255	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FYA61_RS13270	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FYA61_RS13290	COG0165	Argininosuccinate lyase
FYA61_RS13345	COG0586	Pfam SNARE associated Golgi protein
FYA61_RS13370	COG2951	lytic endotransglycosylase activity
FYA61_RS13375	COG2833	Protein of unknown function (DUF455)
FYA61_RS13390	COG1132	(ABC) transporter
FYA61_RS13405	COG3038	cytochrome b561
FYA61_RS13410	COG3237	CsbD-like
FYA61_RS13430	COG2823	Periplasmic or secreted lipoprotein
FYA61_RS13445	COG0672	)-iron permease
FYA61_RS13460	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
FYA61_RS13465	COG1028	Short-chain dehydrogenase reductase Sdr
FYA61_RS13470	COG3243	poly(R)-hydroxyalkanoic acid synthase
FYA61_RS13480	COG0564	pseudouridine synthase activity
FYA61_RS13490	COG1199	ATP-dependent helicase activity
FYA61_RS13495	COG2183	response to ionizing radiation
FYA61_RS13520	COG4774	siderophore transport
FYA61_RS13530	COG1595	DNA-templated transcription, initiation
FYA61_RS13535	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FYA61_RS13540	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FYA61_RS13545	COG0508	dehydrogenase complex catalyzes the overall conversion of
FYA61_RS13550	COG0567	Dehydrogenase, E1 component
FYA61_RS13555	COG1297	OPT oligopeptide transporter protein
FYA61_RS13565	COG0280	phosphate acetyltransferase
FYA61_RS13565	COG0281	malic enzyme
FYA61_RS13585	COG0488	(ABC) transporter
FYA61_RS13600	COG4608	Belongs to the ABC transporter superfamily
FYA61_RS13605	COG0444	Belongs to the ABC transporter superfamily
FYA61_RS13610	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FYA61_RS13625	COG1215	transferase activity, transferring glycosyl groups
FYA61_RS13630	COG0583	DNA-binding transcription factor activity
FYA61_RS13635	COG1368	sulfuric ester hydrolase activity
FYA61_RS13640	COG1686	Belongs to the peptidase S11 family
FYA61_RS13650	COG1280	lysine exporter protein (LysE YggA)
FYA61_RS13660	COG1064	alcohol dehydrogenase
FYA61_RS13665	COG4191	Histidine kinase
FYA61_RS13670	COG4566	intracellular signal transduction
FYA61_RS13680	COG1802	Transcriptional regulator
FYA61_RS13705	COG3181	Tripartite tricarboxylate transporter family receptor
FYA61_RS13710	COG0513	Belongs to the DEAD box helicase family
FYA61_RS13715	COG0668	transmembrane transport
FYA61_RS13730	COG1595	DNA-templated transcription, initiation
FYA61_RS13770	COG0583	DNA-binding transcription factor activity
FYA61_RS13775	COG0531	amino acid
FYA61_RS13780	COG1982	Orn Lys Arg decarboxylase major
FYA61_RS13805	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FYA61_RS13810	COG0459	protein refolding
FYA61_RS13820	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FYA61_RS13825	COG1252	NADH dehydrogenase
FYA61_RS13830	COG0284	orotidine-5'-phosphate decarboxylase activity
FYA61_RS13840	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FYA61_RS13850	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FYA61_RS13855	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FYA61_RS13885	COG1595	DNA-templated transcription, initiation
FYA61_RS13895	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FYA61_RS13900	COG3639	organic phosphonate transmembrane transporter activity
FYA61_RS13905	COG3639	organic phosphonate transmembrane transporter activity
FYA61_RS13920	COG0742	ribosomal rna small subunit methyltransferase
FYA61_RS13925	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FYA61_RS13930	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FYA61_RS13935	COG3135	benzoate transporter
FYA61_RS13955	COG4774	siderophore transport
FYA61_RS13980	COG1024	Enoyl-CoA hydratase
FYA61_RS13985	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FYA61_RS13990	COG1960	acyl-CoA dehydrogenase activity
FYA61_RS14000	COG0318	PFAM AMP-dependent synthetase and ligase
FYA61_RS14005	COG3181	Tripartite tricarboxylate transporter family receptor
FYA61_RS14015	COG0583	DNA-binding transcription factor activity
FYA61_RS14040	COG0277	FAD linked oxidase domain protein
FYA61_RS14060	COG1802	Transcriptional regulator
FYA61_RS14075	COG2271	Major facilitator Superfamily
FYA61_RS14085	COG0583	DNA-binding transcription factor activity
FYA61_RS14110	COG0012	GTP binding
FYA61_RS14120	COG0193	aminoacyl-tRNA hydrolase activity
FYA61_RS14125	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FYA61_RS14130	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FYA61_RS14140	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FYA61_RS14155	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FYA61_RS14180	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FYA61_RS14190	COG1368	sulfuric ester hydrolase activity
FYA61_RS14195	COG2186	Transcriptional regulator
FYA61_RS14205	COG3181	Tripartite tricarboxylate transporter family receptor
FYA61_RS14220	COG0277	FAD linked oxidase domain protein
FYA61_RS14235	COG0166	Belongs to the GPI family
FYA61_RS14240	COG0438	transferase activity, transferring glycosyl groups
FYA61_RS14245	COG0438	transferase activity, transferring glycosyl groups
FYA61_RS14260	COG0438	transferase activity, transferring glycosyl groups
FYA61_RS14275	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FYA61_RS14280	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FYA61_RS14295	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
FYA61_RS14305	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FYA61_RS14315	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FYA61_RS14320	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FYA61_RS14335	COG0747	negative chemotaxis
FYA61_RS14345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FYA61_RS14350	COG4172	Belongs to the ABC transporter superfamily
FYA61_RS14375	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FYA61_RS14375	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FYA61_RS14380	COG0509	glycine decarboxylation via glycine cleavage system
FYA61_RS14385	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FYA61_RS14390	COG2081	HI0933 family
FYA61_RS14405	COG0456	acetyltransferase
FYA61_RS14410	COG0717	Belongs to the dCTP deaminase family
FYA61_RS14425	COG0489	protein tyrosine kinase activity
FYA61_RS14435	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FYA61_RS14435	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FYA61_RS14460	COG3539	Fimbrial protein
FYA61_RS14475	COG0745	RESPONSE REGULATOR receiver
FYA61_RS14505	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
FYA61_RS14520	COG2084	Dehydrogenase
FYA61_RS14525	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FYA61_RS14550	COG3842	ATPase activity
FYA61_RS14555	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FYA61_RS14560	COG1960	acyl-CoA dehydrogenase activity
FYA61_RS14570	COG0583	DNA-binding transcription factor activity
FYA61_RS14580	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYA61_RS14585	COG1024	Enoyl-CoA hydratase
FYA61_RS14605	COG0583	DNA-binding transcription factor activity
FYA61_RS14610	COG1408	metallophosphoesterase
FYA61_RS14615	COG0625	glutathione transferase activity
FYA61_RS14650	COG0426	domain, Protein
FYA61_RS14650	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FYA61_RS14655	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FYA61_RS14660	COG0583	DNA-binding transcription factor activity
FYA61_RS14670	COG1024	Enoyl-CoA hydratase
FYA61_RS14680	COG1960	acyl-CoA dehydrogenase activity
FYA61_RS14685	COG1028	Short-chain dehydrogenase reductase Sdr
FYA61_RS14690	COG1028	Short-chain dehydrogenase reductase Sdr
FYA61_RS14710	COG3181	Tripartite tricarboxylate transporter family receptor
FYA61_RS14715	COG1028	Short-chain dehydrogenase reductase Sdr
FYA61_RS14725	COG3181	Tripartite tricarboxylate transporter family receptor
FYA61_RS14765	COG0583	DNA-binding transcription factor activity
FYA61_RS14770	COG1960	acyl-CoA dehydrogenase activity
FYA61_RS14775	COG3181	Tripartite tricarboxylate transporter family receptor
FYA61_RS14780	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYA61_RS14785	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FYA61_RS14810	COG0560	Phosphoserine phosphatase
FYA61_RS14815	COG0583	DNA-binding transcription factor activity
FYA61_RS14825	COG3842	ATPase activity
FYA61_RS14840	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FYA61_RS14860	COG0625	glutathione transferase activity
FYA61_RS14900	COG4336	lyase activity
FYA61_RS14910	COG0326	Molecular chaperone. Has ATPase activity
FYA61_RS14915	COG2233	PERMEase
FYA61_RS14955	COG2818	Glycosylase
FYA61_RS14960	COG0727	PFAM Uncharacterised protein family (UPF0153)
FYA61_RS14985	COG0402	S-adenosylhomocysteine deaminase activity
FYA61_RS15000	COG0156	8-amino-7-oxononanoate synthase activity
FYA61_RS15005	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FYA61_RS15055	COG1464	Belongs to the NlpA lipoprotein family
FYA61_RS15060	COG2011	ABC-type metal ion transport system permease component
FYA61_RS15065	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FYA61_RS15070	COG1501	Belongs to the glycosyl hydrolase 31 family
FYA61_RS15075	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FYA61_RS15075	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FYA61_RS15080	COG0483	inositol monophosphate 1-phosphatase activity
FYA61_RS15085	COG0318	PFAM AMP-dependent synthetase and ligase
FYA61_RS15090	COG1473	amidohydrolase
FYA61_RS15095	COG0583	DNA-binding transcription factor activity
FYA61_RS15100	COG2855	membrane
FYA61_RS15110	COG2239	Acts as a magnesium transporter
FYA61_RS15125	COG1522	sequence-specific DNA binding
FYA61_RS15160	COG0330	HflC and HflK could
FYA61_RS15165	COG0330	HflC and HflK could
FYA61_RS15170	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FYA61_RS15175	COG1923	regulation of RNA biosynthetic process
FYA61_RS15185	COG1160	GTP binding
FYA61_RS15190	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FYA61_RS15195	COG2976	Protein conserved in bacteria
FYA61_RS15200	COG0124	histidyl-tRNA synthetase
FYA61_RS15215	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FYA61_RS15220	COG0105	UTP biosynthetic process
FYA61_RS15225	COG0525	valine-tRNA ligase activity
FYA61_RS15235	COG0336	Belongs to the RNA methyltransferase TrmD family
FYA61_RS15240	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FYA61_RS15245	COG0228	four-way junction DNA binding
FYA61_RS15250	COG0425	Belongs to the sulfur carrier protein TusA family
FYA61_RS15255	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FYA61_RS15320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FYA61_RS15325	COG0543	2 iron, 2 sulfur cluster binding
FYA61_RS15325	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FYA61_RS15330	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FYA61_RS15335	COG2076	Multidrug Resistance protein
FYA61_RS15340	COG0633	Ferredoxin
FYA61_RS15340	COG3217	Mosc domain protein beta barrel domain protein
FYA61_RS15345	COG5285	phytanoyl-CoA dioxygenase
FYA61_RS15350	COG0662	Cupin 2, conserved barrel domain protein
FYA61_RS15360	COG0456	acetyltransferase
FYA61_RS15375	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FYA61_RS15405	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FYA61_RS15415	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FYA61_RS15420	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FYA61_RS15425	COG1760	l-serine dehydratase
FYA61_RS15430	COG1283	sodium-dependent phosphate transmembrane transporter activity
FYA61_RS15435	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FYA61_RS15440	COG0412	Dienelactone hydrolase
FYA61_RS15445	COG0428	transporter
FYA61_RS15455	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FYA61_RS15465	COG1845	cytochrome c oxidase, subunit III
FYA61_RS15470	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FYA61_RS15480	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FYA61_RS15480	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FYA61_RS15505	COG1942	4-Oxalocrotonate Tautomerase
FYA61_RS15515	COG4176	ABC-type proline glycine betaine transport system permease component
FYA61_RS15535	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FYA61_RS15540	COG2814	Major facilitator Superfamily
FYA61_RS15545	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FYA61_RS15550	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FYA61_RS15575	COG1846	Transcriptional regulator
FYA61_RS15580	COG2814	Major facilitator Superfamily
FYA61_RS15585	COG0495	leucyl-tRNA aminoacylation
FYA61_RS15600	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FYA61_RS15620	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYA61_RS15625	COG2274	protein secretion by the type I secretion system
FYA61_RS15670	COG0427	acetyl-CoA hydrolase
FYA61_RS15680	COG1511	domain protein
FYA61_RS15680	COG3264	Mechanosensitive ion channel
FYA61_RS15685	COG0730	response to heat
FYA61_RS15700	COG2176	DNA-directed DNA polymerase activity
FYA61_RS15720	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FYA61_RS15725	COG3384	dioxygenase
FYA61_RS15740	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FYA61_RS15810	COG4964	Belongs to the GSP D family
FYA61_RS15855	COG1846	Transcriptional regulator
FYA61_RS15890	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FYA61_RS15900	COG2070	2-Nitropropane dioxygenase
FYA61_RS15905	COG2070	2-Nitropropane dioxygenase
FYA61_RS15915	COG2610	gluconate transmembrane transporter activity
FYA61_RS15930	COG1408	metallophosphoesterase
FYA61_RS15935	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FYA61_RS15935	COG0493	'glutamate synthase
FYA61_RS15940	COG2199	diguanylate cyclase activity
FYA61_RS15945	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FYA61_RS15980	COG2159	amidohydrolase
FYA61_RS15990	COG0583	DNA-binding transcription factor activity
FYA61_RS16005	COG1024	Enoyl-CoA hydratase
FYA61_RS16010	COG2186	Transcriptional regulator
FYA61_RS16015	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYA61_RS16025	COG0833	amino acid
FYA61_RS16035	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FYA61_RS16070	COG5265	(ABC) transporter
FYA61_RS16110	COG1971	Probably functions as a manganese efflux pump
FYA61_RS16115	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FYA61_RS16125	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FYA61_RS16130	COG2814	Major facilitator Superfamily
FYA61_RS16155	COG4608	Belongs to the ABC transporter superfamily
FYA61_RS16175	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FYA61_RS16185	COG3383	formate dehydrogenase (NAD+) activity
FYA61_RS16200	COG0747	negative chemotaxis
FYA61_RS16210	COG0625	glutathione transferase activity
FYA61_RS16240	COG1595	DNA-templated transcription, initiation
FYA61_RS16250	COG4774	siderophore transport
FYA61_RS16265	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FYA61_RS16280	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FYA61_RS16285	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FYA61_RS16310	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYA61_RS16315	COG1024	Enoyl-CoA hydratase
FYA61_RS16350	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FYA61_RS16355	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FYA61_RS16360	COG1116	anion transmembrane transporter activity
FYA61_RS16370	COG3585	molybdate ion transport
FYA61_RS16430	COG0583	DNA-binding transcription factor activity
FYA61_RS16435	COG4948	Mandelate Racemase Muconate Lactonizing
FYA61_RS16440	COG3181	Tripartite tricarboxylate transporter family receptor
FYA61_RS16470	COG3181	Tripartite tricarboxylate transporter family receptor
FYA61_RS16505	COG4177	L-phenylalanine transmembrane transporter activity
FYA61_RS16530	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FYA61_RS16545	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FYA61_RS16550	COG1538	Outer membrane efflux protein
FYA61_RS16555	COG1136	(ABC) transporter
FYA61_RS16555	COG0577	efflux transmembrane transporter activity
FYA61_RS16560	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYA61_RS16575	COG0259	pyridoxamine-phosphate oxidase activity
FYA61_RS16580	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FYA61_RS16585	COG0579	oxidoreductase
FYA61_RS16595	COG0405	Gamma-glutamyltransferase
FYA61_RS16605	COG3181	Tripartite tricarboxylate transporter family receptor
FYA61_RS16615	COG0114	fumarate hydratase activity
FYA61_RS16620	COG0802	atpase or kinase
FYA61_RS16625	COG0860	N-Acetylmuramoyl-L-alanine amidase
FYA61_RS16630	COG0586	Pfam SNARE associated Golgi protein
FYA61_RS16635	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FYA61_RS16640	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FYA61_RS16645	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FYA61_RS16660	COG0617	tRNA 3'-terminal CCA addition
FYA61_RS16695	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
FYA61_RS16705	COG1024	Enoyl-CoA hydratase
FYA61_RS16715	COG2188	Transcriptional regulator
FYA61_RS16720	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FYA61_RS16735	COG0752	glycyl-tRNA synthetase alpha subunit
FYA61_RS16740	COG0751	glycine-tRNA ligase activity
FYA61_RS16745	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FYA61_RS16750	COG0204	Acyl-transferase
FYA61_RS16780	COG0242	peptide deformylase activity
FYA61_RS16790	COG0700	Nucleoside recognition
FYA61_RS16795	COG0469	pyruvate kinase activity
FYA61_RS16800	COG1929	Belongs to the glycerate kinase type-1 family
FYA61_RS16810	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FYA61_RS16815	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FYA61_RS16820	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FYA61_RS16830	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FYA61_RS16840	COG2154	pterin-4-alpha-carbinolamine dehydratase
FYA61_RS16845	COG2885	chlorophyll binding
FYA61_RS16855	COG0667	Aldo Keto reductase
FYA61_RS16865	COG3181	Tripartite tricarboxylate transporter family receptor
FYA61_RS16885	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FYA61_RS16890	COG0288	reversible hydration of carbon dioxide
FYA61_RS16910	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FYA61_RS16920	COG4829	muconolactone delta-isomerase
FYA61_RS16925	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FYA61_RS16935	COG1414	Transcriptional regulator
FYA61_RS16940	COG1028	Short-chain dehydrogenase reductase Sdr
FYA61_RS16945	COG2031	fatty acid transporter
FYA61_RS16950	COG1250	3-hydroxyacyl-CoA dehydrogenase
FYA61_RS16960	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FYA61_RS16965	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FYA61_RS16980	COG0129	dihydroxy-acid dehydratase activity
FYA61_RS16985	COG1609	Transcriptional regulator
FYA61_RS17010	COG4106	trans-aconitate 2-methyltransferase activity
FYA61_RS17025	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FYA61_RS17060	COG0163	prenyltransferase activity
FYA61_RS17065	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FYA61_RS17070	COG2890	protein-(glutamine-N5) methyltransferase activity
FYA61_RS17075	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FYA61_RS17080	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FYA61_RS17095	COG3712	iron ion homeostasis
FYA61_RS17125	COG0659	secondary active sulfate transmembrane transporter activity
FYA61_RS17145	COG1028	Short-chain dehydrogenase reductase Sdr
FYA61_RS17155	COG4774	siderophore transport
FYA61_RS17165	COG1595	DNA-templated transcription, initiation
FYA61_RS17180	COG0142	geranyltranstransferase activity
FYA61_RS17185	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FYA61_RS17190	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FYA61_RS17195	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FYA61_RS17200	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FYA61_RS17220	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FYA61_RS17220	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FYA61_RS17225	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FYA61_RS17240	COG0583	DNA-binding transcription factor activity
FYA61_RS17245	COG0861	Integral membrane protein TerC family
FYA61_RS17260	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FYA61_RS17265	COG0793	Belongs to the peptidase S41A family
FYA61_RS17270	COG4942	peptidase
FYA61_RS17275	COG0588	phosphoglycerate mutase activity
FYA61_RS17285	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FYA61_RS17290	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FYA61_RS17295	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FYA61_RS17300	COG3181	Tripartite tricarboxylate transporter family receptor
FYA61_RS17315	COG2226	methyltransferase
FYA61_RS17320	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
FYA61_RS17325	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FYA61_RS17335	COG2204	response regulator
FYA61_RS17340	COG5000	phosphorelay sensor kinase activity
FYA61_RS17350	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FYA61_RS17350	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FYA61_RS17385	COG2188	Transcriptional regulator
FYA61_RS17400	COG0583	DNA-binding transcription factor activity
FYA61_RS17405	COG1012	belongs to the aldehyde dehydrogenase family
FYA61_RS17425	COG0546	phosphoglycolate phosphatase activity
FYA61_RS17440	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FYA61_RS17445	COG0242	peptide deformylase activity
FYA61_RS17455	COG1522	sequence-specific DNA binding
FYA61_RS17460	COG2879	small protein
FYA61_RS17465	COG1966	Carbon starvation protein
FYA61_RS17495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYA61_RS17500	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FYA61_RS17505	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FYA61_RS17510	COG3181	Tripartite tricarboxylate transporter family receptor
FYA61_RS17575	COG1172	Belongs to the binding-protein-dependent transport system permease family
FYA61_RS17610	COG0640	Transcriptional regulator
FYA61_RS17650	COG0735	belongs to the Fur family
FYA61_RS17655	COG2207	Transcriptional regulator
FYA61_RS17660	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FYA61_RS17665	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FYA61_RS17670	COG0513	Belongs to the DEAD box helicase family
FYA61_RS17695	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FYA61_RS17710	COG1305	Transglutaminase-like
FYA61_RS17750	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FYA61_RS17755	COG1950	PFAM Membrane protein of
FYA61_RS17780	COG0024	Methionine aminopeptidase
FYA61_RS17785	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FYA61_RS17795	COG1560	Kdo2-lipid A biosynthetic process
FYA61_RS17800	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FYA61_RS17810	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FYA61_RS17845	COG0735	belongs to the Fur family
FYA61_RS17850	COG0523	cobalamin synthesis protein
FYA61_RS17865	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FYA61_RS17875	COG2096	Adenosyltransferase
FYA61_RS17880	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FYA61_RS17885	COG0321	lipoyl(octanoyl) transferase activity
FYA61_RS17895	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FYA61_RS17900	COG1686	Belongs to the peptidase S11 family
FYA61_RS17925	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FYA61_RS17935	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FYA61_RS17945	COG0859	PFAM glycosyl transferase family 9
FYA61_RS17980	COG0477	Major facilitator Superfamily
FYA61_RS17995	COG3568	Endonuclease Exonuclease Phosphatase
FYA61_RS18000	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FYA61_RS18030	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FYA61_RS18035	COG1956	GAF domain-containing protein
FYA61_RS18040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FYA61_RS18055	COG2186	Transcriptional regulator
FYA61_RS18060	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FYA61_RS18075	COG1840	ABC-type Fe3 transport system, periplasmic component
FYA61_RS18115	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FYA61_RS18120	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FYA61_RS18125	COG1086	Polysaccharide biosynthesis protein
FYA61_RS18155	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FYA61_RS18165	COG1028	Short-chain dehydrogenase reductase Sdr
FYA61_RS18170	COG1012	belongs to the aldehyde dehydrogenase family
FYA61_RS18195	COG1522	sequence-specific DNA binding
FYA61_RS18200	COG3781	membrane
FYA61_RS18240	COG2200	EAL domain
FYA61_RS18250	COG0592	DNA-directed DNA polymerase activity
FYA61_RS18255	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FYA61_RS18260	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FYA61_RS18265	COG0594	ribonuclease P activity
FYA61_RS18270	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FYA61_RS18275	COG0706	membrane insertase activity
FYA61_RS18280	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FYA61_RS18285	COG1473	amidohydrolase
FYA61_RS18290	COG4608	Belongs to the ABC transporter superfamily
FYA61_RS18295	COG0444	Belongs to the ABC transporter superfamily
FYA61_RS18300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FYA61_RS18305	COG0601	transmembrane transport
FYA61_RS18315	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FYA61_RS18320	COG1505	serine-type exopeptidase activity
FYA61_RS18330	COG0280	phosphate acetyltransferase
FYA61_RS18330	COG0281	malic enzyme
FYA61_RS18360	COG0436	Aminotransferase
FYA61_RS18365	COG1278	Cold shock