locus-tag	class	description
FYA90_RS00010	COG0521	Mo-molybdopterin cofactor biosynthetic process
FYA90_RS00020	COG0739	heme binding
FYA90_RS00030	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FYA90_RS00070	COG0456	acetyltransferase
FYA90_RS00075	COG1301	dicarboxylic acid transport
FYA90_RS00085	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FYA90_RS00090	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FYA90_RS00095	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FYA90_RS00100	COG0009	L-threonylcarbamoyladenylate synthase
FYA90_RS00110	COG4771	TonB-dependent receptor
FYA90_RS00140	COG1960	acyl-CoA dehydrogenase activity
FYA90_RS00145	COG0028	Belongs to the TPP enzyme family
FYA90_RS00150	COG0583	DNA-binding transcription factor activity
FYA90_RS00155	COG4974	Belongs to the 'phage' integrase family
FYA90_RS00160	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FYA90_RS00165	COG1686	Belongs to the peptidase S11 family
FYA90_RS00195	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FYA90_RS00200	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FYA90_RS00205	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FYA90_RS00225	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FYA90_RS00230	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FYA90_RS00235	COG0505	Belongs to the CarA family
FYA90_RS00240	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FYA90_RS00250	COG1028	Short-chain dehydrogenase reductase Sdr
FYA90_RS00255	COG0406	alpha-ribazole phosphatase activity
FYA90_RS00285	COG2233	PERMEase
FYA90_RS00290	COG3620	sequence-specific DNA binding
FYA90_RS00300	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FYA90_RS00310	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FYA90_RS00325	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FYA90_RS00340	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FYA90_RS00360	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FYA90_RS00420	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FYA90_RS00450	COG0540	Belongs to the ATCase OTCase family
FYA90_RS00455	COG2974	May be involved in recombination
FYA90_RS00480	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FYA90_RS00485	COG2137	regulation of response to DNA damage stimulus
FYA90_RS00495	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FYA90_RS00515	COG0045	succinate-CoA ligase (ADP-forming) activity
FYA90_RS00520	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FYA90_RS00525	COG0861	Integral membrane protein TerC family
FYA90_RS00530	COG0861	Integral membrane protein TerC family
FYA90_RS00535	COG0181	hydroxymethylbilane synthase activity
FYA90_RS00575	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FYA90_RS00630	COG1450	Type ii and iii secretion system protein
FYA90_RS00680	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FYA90_RS00700	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FYA90_RS00720	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FYA90_RS00725	COG0501	Belongs to the peptidase M48B family
FYA90_RS00730	COG2197	response regulator
FYA90_RS00755	COG0066	3-isopropylmalate dehydratase activity
FYA90_RS00765	COG0473	3-isopropylmalate dehydrogenase activity
FYA90_RS00770	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FYA90_RS00780	COG0101	tRNA pseudouridine synthase activity
FYA90_RS00785	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FYA90_RS00790	COG0135	phosphoribosylanthranilate isomerase activity
FYA90_RS00810	COG2801	Transposase and inactivated derivatives
FYA90_RS00815	COG2801	Transposase and inactivated derivatives
FYA90_RS00855	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FYA90_RS00860	COG2197	response regulator
FYA90_RS00870	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FYA90_RS00885	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FYA90_RS00890	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FYA90_RS00900	COG1764	response to oxidative stress
FYA90_RS00920	COG0765	amino acid transport
FYA90_RS00925	COG0765	amino acid transport
FYA90_RS00935	COG0756	dUTP diphosphatase activity
FYA90_RS00965	COG1522	sequence-specific DNA binding
FYA90_RS00985	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FYA90_RS00990	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FYA90_RS00995	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FYA90_RS01000	COG0196	riboflavin kinase activity
FYA90_RS01040	COG0210	DNA helicase
FYA90_RS01045	COG4771	TonB-dependent receptor
FYA90_RS01050	COG0488	(ABC) transporter
FYA90_RS01055	COG2890	protein-(glutamine-N5) methyltransferase activity
FYA90_RS01065	COG2171	N-acyltransferase activity
FYA90_RS01120	COG2801	Transposase and inactivated derivatives
FYA90_RS01160	COG2814	Major facilitator Superfamily
FYA90_RS01185	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FYA90_RS01190	COG2900	Belongs to the SlyX family
FYA90_RS01205	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FYA90_RS01225	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FYA90_RS01250	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FYA90_RS01255	COG0583	DNA-binding transcription factor activity
FYA90_RS01270	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FYA90_RS01275	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FYA90_RS01290	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FYA90_RS01295	COG0508	dehydrogenase complex catalyzes the overall conversion of
FYA90_RS01300	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FYA90_RS01310	COG4566	intracellular signal transduction
FYA90_RS01315	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FYA90_RS01335	COG1999	signal sequence binding
FYA90_RS01355	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYA90_RS01360	COG0583	DNA-binding transcription factor activity
FYA90_RS01365	COG1187	pseudouridine synthase activity
FYA90_RS01370	COG3161	chorismate lyase activity
FYA90_RS01385	COG1280	lysine exporter protein (LysE YggA)
FYA90_RS01425	COG1129	ABC transporter
FYA90_RS01440	COG0583	DNA-binding transcription factor activity
FYA90_RS01475	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FYA90_RS01490	COG1183	phosphatidylcholine synthase activity
FYA90_RS01500	COG0440	acetolactate synthase activity
FYA90_RS01530	COG3022	response to hydroperoxide
FYA90_RS01540	COG1028	Short-chain dehydrogenase reductase Sdr
FYA90_RS01555	COG3486	L-lysine 6-monooxygenase (NADPH) activity
FYA90_RS01615	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FYA90_RS01650	COG2733	membrane
FYA90_RS01675	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FYA90_RS01695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYA90_RS01700	COG1129	ABC transporter
FYA90_RS01700	COG0842	Transport permease protein
FYA90_RS01705	COG0842	Transport permease protein
FYA90_RS01725	COG2259	Doxx family
FYA90_RS01755	COG0415	Belongs to the DNA photolyase family
FYA90_RS01775	COG0386	Belongs to the glutathione peroxidase family
FYA90_RS01790	COG0095	Lipoate-protein ligase
FYA90_RS01800	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FYA90_RS01810	COG0010	Belongs to the arginase family
FYA90_RS01820	COG0765	amino acid transport
FYA90_RS01825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYA90_RS01840	COG0084	hydrolase, TatD family'
FYA90_RS01850	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FYA90_RS01855	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FYA90_RS01865	COG2175	clavaminate synthase activity
FYA90_RS01870	COG0583	DNA-binding transcription factor activity
FYA90_RS01895	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FYA90_RS01905	COG2914	Belongs to the UPF0125 (RnfH) family
FYA90_RS01915	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FYA90_RS01950	COG0519	Catalyzes the synthesis of GMP from XMP
FYA90_RS01950	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FYA90_RS01960	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FYA90_RS01970	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FYA90_RS01975	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FYA90_RS01980	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FYA90_RS01990	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FYA90_RS01995	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FYA90_RS02005	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FYA90_RS02015	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FYA90_RS02025	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FYA90_RS02030	COG0233	cytoplasmic translational termination
FYA90_RS02035	COG0528	UMP kinase activity
FYA90_RS02040	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FYA90_RS02045	COG0052	Belongs to the universal ribosomal protein uS2 family
FYA90_RS02050	COG0024	Methionine aminopeptidase
FYA90_RS02055	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FYA90_RS02080	COG1286	toxin biosynthetic process
FYA90_RS02090	COG0285	dihydrofolate synthase activity
FYA90_RS02100	COG3181	Tripartite tricarboxylate transporter family receptor
FYA90_RS02105	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYA90_RS02145	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FYA90_RS02155	COG1677	Flagellar hook-basal body complex protein FliE
FYA90_RS02165	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FYA90_RS02170	COG1317	bacterial-type flagellum organization
FYA90_RS02190	COG1580	Controls the rotational direction of flagella during chemotaxis
FYA90_RS02200	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FYA90_RS02225	COG0840	transmembrane signaling receptor activity
FYA90_RS02230	COG0840	transmembrane signaling receptor activity
FYA90_RS02255	COG1191	sigma factor activity
FYA90_RS02290	COG2199	diguanylate cyclase activity
FYA90_RS02290	COG2203	Gaf domain
FYA90_RS02325	COG1126	abc transporter atp-binding protein
FYA90_RS02330	COG0765	amino acid transport
FYA90_RS02335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYA90_RS02380	COG2200	EAL domain
FYA90_RS02415	COG2197	response regulator
FYA90_RS02420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYA90_RS02420	COG2205	protein histidine kinase activity
FYA90_RS02445	COG0076	glutamate decarboxylase activity
FYA90_RS02450	COG2985	domain, Protein
FYA90_RS02455	COG3189	MarR family transcriptional regulator
FYA90_RS02465	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FYA90_RS02475	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FYA90_RS02475	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FYA90_RS02485	COG0028	Belongs to the TPP enzyme family
FYA90_RS02495	COG1012	belongs to the aldehyde dehydrogenase family
FYA90_RS02505	COG0688	phosphatidylethanolamine metabolic process
FYA90_RS02510	COG1304	FMN binding
FYA90_RS02515	COG1464	Belongs to the NlpA lipoprotein family
FYA90_RS02535	COG0697	spore germination
FYA90_RS02540	COG2133	pyrroloquinoline quinone binding
FYA90_RS02545	COG0625	glutathione transferase activity
FYA90_RS02555	COG1794	racemase activity, acting on amino acids and derivatives
FYA90_RS02575	COG0559	Belongs to the binding-protein-dependent transport system permease family
FYA90_RS02585	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FYA90_RS02600	COG1175	transmembrane transport
FYA90_RS02605	COG0395	ABC-type sugar transport system, permease component
FYA90_RS02610	COG3842	ATPase activity
FYA90_RS02635	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FYA90_RS02650	COG0438	transferase activity, transferring glycosyl groups
FYA90_RS02675	COG0463	Glycosyl transferase, family 2
FYA90_RS02695	COG0583	DNA-binding transcription factor activity
FYA90_RS02700	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FYA90_RS02730	COG1840	ABC-type Fe3 transport system, periplasmic component
FYA90_RS02740	COG3842	ATPase activity
FYA90_RS02745	COG1741	Belongs to the pirin family
FYA90_RS02750	COG1741	Belongs to the pirin family
FYA90_RS02755	COG0583	DNA-binding transcription factor activity
FYA90_RS02770	COG0174	glutamine synthetase
FYA90_RS02775	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FYA90_RS02780	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FYA90_RS02790	COG0840	transmembrane signaling receptor activity
FYA90_RS02800	COG0583	DNA-binding transcription factor activity
FYA90_RS02805	COG1960	acyl-CoA dehydrogenase activity
FYA90_RS02810	COG2079	MmgE PrpD family protein
FYA90_RS02820	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FYA90_RS02825	COG1561	YicC-like family, N-terminal region
FYA90_RS02835	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FYA90_RS02840	COG0791	NLP P60 protein
FYA90_RS02845	COG1028	Short-chain dehydrogenase reductase Sdr
FYA90_RS02850	COG0194	GDP metabolic process
FYA90_RS02855	COG1758	RNA polymerase activity
FYA90_RS02860	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FYA90_RS02865	COG1126	abc transporter atp-binding protein
FYA90_RS02870	COG0765	amino acid transport
FYA90_RS02875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYA90_RS02885	COG2831	hemolysin activation secretion protein
FYA90_RS02900	COG3121	Chaperone
FYA90_RS02930	COG4181	ATPase activity
FYA90_RS02940	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FYA90_RS02945	COG0584	glycerophosphoryl diester phosphodiesterase
FYA90_RS02950	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FYA90_RS02970	COG2217	Heavy metal translocating P-type atpase
FYA90_RS02975	COG0789	Transcriptional regulator
FYA90_RS02980	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FYA90_RS03020	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FYA90_RS03030	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FYA90_RS03055	COG0583	DNA-binding transcription factor activity
FYA90_RS03060	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FYA90_RS03065	COG2252	PERMEase
FYA90_RS03070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FYA90_RS03075	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FYA90_RS03110	COG0488	(ABC) transporter
FYA90_RS03115	COG1619	proteins homologs of microcin C7 resistance protein MccF
FYA90_RS03120	COG0590	tRNA wobble adenosine to inosine editing
FYA90_RS03135	COG1320	monovalent cation:proton antiporter activity
FYA90_RS03140	COG2212	antiporter activity
FYA90_RS03145	COG1863	multisubunit Na H antiporter MnhE subunit
FYA90_RS03150	COG0651	ATP synthesis coupled electron transport
FYA90_RS03155	COG1006	Multisubunit Na H antiporter MnhC subunit
FYA90_RS03165	COG3181	Tripartite tricarboxylate transporter family receptor
FYA90_RS03190	COG0420	3'-5' exonuclease activity
FYA90_RS03225	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FYA90_RS03235	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FYA90_RS03245	COG2130	NADP-dependent
FYA90_RS03250	COG1309	transcriptional regulator
FYA90_RS03260	COG1131	(ABC) transporter
FYA90_RS03275	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FYA90_RS03315	COG0720	synthase
FYA90_RS03350	COG0587	DNA-directed DNA polymerase activity
FYA90_RS03360	COG0390	transport system, permease component
FYA90_RS03365	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FYA90_RS03370	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
FYA90_RS03425	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FYA90_RS03450	COG5507	3-demethylubiquinone-9 3-methyltransferase
FYA90_RS03485	COG1396	sequence-specific DNA binding
FYA90_RS03510	COG0583	DNA-binding transcription factor activity
FYA90_RS03515	COG2814	Major facilitator Superfamily
FYA90_RS03540	COG2807	transmembrane transport
FYA90_RS03545	COG2207	Transcriptional regulator
FYA90_RS03550	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FYA90_RS03555	COG2814	Major facilitator Superfamily
FYA90_RS03570	COG1012	belongs to the aldehyde dehydrogenase family
FYA90_RS03605	COG0583	DNA-binding transcription factor activity
FYA90_RS03630	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FYA90_RS03655	COG0384	phenazine biosynthesis protein PhzF
FYA90_RS03660	COG1733	regulation of RNA biosynthetic process
FYA90_RS03705	COG0519	Catalyzes the synthesis of GMP from XMP
FYA90_RS03705	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FYA90_RS03720	COG1695	Transcriptional regulator
FYA90_RS03735	COG2072	flavoprotein involved in K transport
FYA90_RS03740	COG0601	transmembrane transport
FYA90_RS03760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FYA90_RS03770	COG4608	Belongs to the ABC transporter superfamily
FYA90_RS03775	COG0747	negative chemotaxis
FYA90_RS03820	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FYA90_RS03840	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FYA90_RS03840	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FYA90_RS03855	COG0613	PHP domain protein
FYA90_RS03915	COG1012	belongs to the aldehyde dehydrogenase family
FYA90_RS03925	COG0583	DNA-binding transcription factor activity
FYA90_RS03945	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FYA90_RS03955	COG3181	Tripartite tricarboxylate transporter family receptor
FYA90_RS03965	COG3181	Tripartite tricarboxylate transporter family receptor
FYA90_RS04000	COG1595	DNA-templated transcription, initiation
FYA90_RS04005	COG3712	iron ion homeostasis
FYA90_RS04015	COG0084	hydrolase, TatD family'
FYA90_RS04020	COG1136	(ABC) transporter
FYA90_RS04045	COG1028	Short-chain dehydrogenase reductase Sdr
FYA90_RS04050	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FYA90_RS04060	COG1803	Methylglyoxal synthase
FYA90_RS04080	COG2801	Transposase and inactivated derivatives
FYA90_RS04085	COG2801	Transposase and inactivated derivatives
FYA90_RS04110	COG2975	iron-sulfur cluster assembly
FYA90_RS04115	COG0633	Ferredoxin
FYA90_RS04120	COG0443	Heat shock 70 kDa protein
FYA90_RS04125	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FYA90_RS04130	COG0316	Belongs to the HesB IscA family
FYA90_RS04135	COG0822	iron-sulfur transferase activity
FYA90_RS04140	COG1104	cysteine desulfurase activity
FYA90_RS04150	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FYA90_RS04155	COG0556	nucleotide-excision repair
FYA90_RS04170	COG0583	DNA-binding transcription factor activity
FYA90_RS04190	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FYA90_RS04230	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FYA90_RS04245	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FYA90_RS04255	COG0740	serine-type endopeptidase activity
FYA90_RS04260	COG0544	peptidyl-prolyl cis-trans isomerase activity
FYA90_RS04305	COG2801	Transposase and inactivated derivatives
FYA90_RS04315	COG1278	Cold shock
FYA90_RS04345	COG2433	Pfam Transposase IS66
FYA90_RS04405	COG1530	ribonuclease E activity
FYA90_RS04435	COG1846	Transcriptional regulator
FYA90_RS04445	COG1566	PFAM secretion protein HlyD family protein
FYA90_RS04450	COG2814	Major facilitator Superfamily
FYA90_RS04475	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FYA90_RS04480	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FYA90_RS04485	COG0433	COG0433 Predicted ATPase
FYA90_RS04490	COG0217	transcriptional regulatory protein
FYA90_RS04495	COG0151	Belongs to the GarS family
FYA90_RS04505	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FYA90_RS04510	COG0799	negative regulation of ribosome biogenesis
FYA90_RS04515	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FYA90_RS04520	COG0424	maF-like protein
FYA90_RS04530	COG4191	Histidine kinase
FYA90_RS04535	COG2204	response regulator
FYA90_RS04575	COG0803	Belongs to the bacterial solute-binding protein 9 family
FYA90_RS04580	COG1121	(ABC) transporter
FYA90_RS04585	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FYA90_RS04590	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FYA90_RS04605	COG4993	Dehydrogenase
FYA90_RS04615	COG4772	TonB-dependent receptor
FYA90_RS04620	COG2814	Major facilitator Superfamily
FYA90_RS04640	COG0037	tRNA processing
FYA90_RS04645	COG0825	malonyl-CoA metabolic process
FYA90_RS04655	COG0215	cysteine-tRNA ligase activity
FYA90_RS04665	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FYA90_RS04670	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FYA90_RS04675	COG1968	undecaprenyl-diphosphatase activity
FYA90_RS04680	COG1253	flavin adenine dinucleotide binding
FYA90_RS04685	COG0483	inositol monophosphate 1-phosphatase activity
FYA90_RS04705	COG0668	transmembrane transport
FYA90_RS04730	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FYA90_RS04740	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FYA90_RS04755	COG1802	Transcriptional regulator
FYA90_RS04775	COG3360	Dodecin
FYA90_RS04800	COG2850	peptidyl-arginine hydroxylation
FYA90_RS04810	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
FYA90_RS04815	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FYA90_RS04820	COG1994	Peptidase M50
FYA90_RS04825	COG0009	L-threonylcarbamoyladenylate synthase
FYA90_RS04830	COG2321	neutral zinc metallopeptidase
FYA90_RS04850	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FYA90_RS04860	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FYA90_RS04870	COG2271	Major facilitator Superfamily
FYA90_RS04950	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
FYA90_RS04970	COG1960	acyl-CoA dehydrogenase activity
FYA90_RS04975	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYA90_RS04980	COG2186	Transcriptional regulator
FYA90_RS05005	COG1595	DNA-templated transcription, initiation
FYA90_RS05040	COG1028	Short-chain dehydrogenase reductase Sdr
FYA90_RS05055	COG0179	Fumarylacetoacetate (FAA) hydrolase
FYA90_RS05075	COG4604	ABC transporter, ATP-binding protein
FYA90_RS05080	COG4605	iron ion homeostasis
FYA90_RS05085	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FYA90_RS05090	COG4607	ABC-type enterochelin transport system periplasmic component
FYA90_RS05105	COG0149	triose-phosphate isomerase activity
FYA90_RS05110	COG0604	alcohol dehydrogenase
FYA90_RS05110	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FYA90_RS05110	COG3321	synthase
FYA90_RS05110	COG4221	oxidoreductase activity
FYA90_RS05140	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FYA90_RS05140	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FYA90_RS05145	COG0668	transmembrane transport
FYA90_RS05150	COG0165	Argininosuccinate lyase
FYA90_RS05160	COG0789	Transcriptional regulator
FYA90_RS05170	COG0501	Belongs to the peptidase M48B family
FYA90_RS05175	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FYA90_RS05200	COG1024	Enoyl-CoA hydratase
FYA90_RS05205	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYA90_RS05225	COG3468	outer membrane autotransporter barrel domain protein
FYA90_RS05270	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FYA90_RS05275	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FYA90_RS05280	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FYA90_RS05285	COG1674	ftsk spoiiie
FYA90_RS05290	COG0492	ferredoxin-NADP+ reductase activity
FYA90_RS05295	COG1193	negative regulation of DNA recombination
FYA90_RS05310	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FYA90_RS05325	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FYA90_RS05330	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FYA90_RS05335	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FYA90_RS05340	COG2205	protein histidine kinase activity
FYA90_RS05345	COG0745	RESPONSE REGULATOR receiver
FYA90_RS05380	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FYA90_RS05400	COG0612	Peptidase, M16
FYA90_RS05410	COG0443	Heat shock 70 kDa protein
FYA90_RS05420	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FYA90_RS05430	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FYA90_RS05435	COG1420	regulation of RNA biosynthetic process
FYA90_RS05440	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FYA90_RS05445	COG0497	DNA recombination
FYA90_RS05475	COG0735	belongs to the Fur family
FYA90_RS05480	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FYA90_RS05525	COG2828	Protein conserved in bacteria
FYA90_RS05530	COG1280	lysine exporter protein (LysE YggA)
FYA90_RS05535	COG3181	Tripartite tricarboxylate transporter family receptor
FYA90_RS05550	COG1028	Short-chain dehydrogenase reductase Sdr
FYA90_RS05555	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FYA90_RS05560	COG1802	Transcriptional regulator
FYA90_RS05570	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FYA90_RS05575	COG1335	isochorismatase
FYA90_RS05610	COG0583	DNA-binding transcription factor activity
FYA90_RS05620	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FYA90_RS05625	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FYA90_RS05630	COG0167	dihydroorotate dehydrogenase activity
FYA90_RS05675	COG1414	Transcriptional regulator
FYA90_RS05695	COG0513	Belongs to the DEAD box helicase family
FYA90_RS05720	COG0429	hydrolase of the alpha beta-hydrolase fold
FYA90_RS05765	COG0006	proline dipeptidase activity
FYA90_RS05775	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FYA90_RS05805	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FYA90_RS05810	COG0632	four-way junction helicase activity
FYA90_RS05825	COG2255	four-way junction helicase activity
FYA90_RS05830	COG0514	ATP-dependent DNA helicase (RecQ)
FYA90_RS05850	COG1294	oxidase, subunit
FYA90_RS05860	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FYA90_RS05870	COG2894	cell division
FYA90_RS05875	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FYA90_RS05900	COG0488	(ABC) transporter
FYA90_RS05915	COG4608	Belongs to the ABC transporter superfamily
FYA90_RS05920	COG0444	Belongs to the ABC transporter superfamily
FYA90_RS05925	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FYA90_RS05940	COG1215	transferase activity, transferring glycosyl groups
FYA90_RS05945	COG0583	DNA-binding transcription factor activity
FYA90_RS05950	COG1368	sulfuric ester hydrolase activity
FYA90_RS05955	COG1686	Belongs to the peptidase S11 family
FYA90_RS05965	COG1280	lysine exporter protein (LysE YggA)
FYA90_RS05975	COG1064	alcohol dehydrogenase
FYA90_RS05985	COG4566	intracellular signal transduction
FYA90_RS05995	COG1802	Transcriptional regulator
FYA90_RS06020	COG3181	Tripartite tricarboxylate transporter family receptor
FYA90_RS06025	COG0513	Belongs to the DEAD box helicase family
FYA90_RS06030	COG0668	transmembrane transport
FYA90_RS06045	COG1595	DNA-templated transcription, initiation
FYA90_RS06090	COG0531	amino acid
FYA90_RS06095	COG1982	Orn Lys Arg decarboxylase major
FYA90_RS06120	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FYA90_RS06125	COG0459	protein refolding
FYA90_RS06135	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FYA90_RS06140	COG1252	NADH dehydrogenase
FYA90_RS06145	COG0284	orotidine-5'-phosphate decarboxylase activity
FYA90_RS06155	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FYA90_RS06165	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FYA90_RS06170	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FYA90_RS06200	COG1595	DNA-templated transcription, initiation
FYA90_RS06210	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FYA90_RS06215	COG3639	organic phosphonate transmembrane transporter activity
FYA90_RS06220	COG3639	organic phosphonate transmembrane transporter activity
FYA90_RS06235	COG0742	ribosomal rna small subunit methyltransferase
FYA90_RS06240	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FYA90_RS06245	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FYA90_RS06250	COG3135	benzoate transporter
FYA90_RS06270	COG4774	siderophore transport
FYA90_RS06295	COG1024	Enoyl-CoA hydratase
FYA90_RS06300	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FYA90_RS06305	COG1960	acyl-CoA dehydrogenase activity
FYA90_RS06315	COG0318	PFAM AMP-dependent synthetase and ligase
FYA90_RS06320	COG3181	Tripartite tricarboxylate transporter family receptor
FYA90_RS06330	COG0583	DNA-binding transcription factor activity
FYA90_RS06375	COG1802	Transcriptional regulator
FYA90_RS06390	COG2271	Major facilitator Superfamily
FYA90_RS06400	COG0583	DNA-binding transcription factor activity
FYA90_RS06425	COG0012	GTP binding
FYA90_RS06435	COG0193	aminoacyl-tRNA hydrolase activity
FYA90_RS06440	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FYA90_RS06445	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FYA90_RS06455	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FYA90_RS06470	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FYA90_RS06495	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FYA90_RS06505	COG1368	sulfuric ester hydrolase activity
FYA90_RS06510	COG2186	Transcriptional regulator
FYA90_RS06520	COG3181	Tripartite tricarboxylate transporter family receptor
FYA90_RS06535	COG0277	FAD linked oxidase domain protein
FYA90_RS06550	COG0166	Belongs to the GPI family
FYA90_RS06555	COG0438	transferase activity, transferring glycosyl groups
FYA90_RS06560	COG0438	transferase activity, transferring glycosyl groups
FYA90_RS06595	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FYA90_RS06610	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
FYA90_RS06620	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FYA90_RS06630	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FYA90_RS06635	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FYA90_RS06650	COG0747	negative chemotaxis
FYA90_RS06660	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FYA90_RS06665	COG4172	Belongs to the ABC transporter superfamily
FYA90_RS06690	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FYA90_RS06690	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FYA90_RS06695	COG0509	glycine decarboxylation via glycine cleavage system
FYA90_RS06700	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FYA90_RS06705	COG2081	HI0933 family
FYA90_RS06720	COG0456	acetyltransferase
FYA90_RS06725	COG0717	Belongs to the dCTP deaminase family
FYA90_RS06740	COG0489	protein tyrosine kinase activity
FYA90_RS06750	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FYA90_RS06750	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FYA90_RS06775	COG3539	Fimbrial protein
FYA90_RS06790	COG0745	RESPONSE REGULATOR receiver
FYA90_RS06820	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
FYA90_RS06840	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FYA90_RS06865	COG3842	ATPase activity
FYA90_RS06870	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FYA90_RS06875	COG1960	acyl-CoA dehydrogenase activity
FYA90_RS06885	COG0583	DNA-binding transcription factor activity
FYA90_RS06895	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYA90_RS06900	COG1024	Enoyl-CoA hydratase
FYA90_RS06920	COG0583	DNA-binding transcription factor activity
FYA90_RS06925	COG1408	metallophosphoesterase
FYA90_RS06930	COG0625	glutathione transferase activity
FYA90_RS06965	COG0426	domain, Protein
FYA90_RS06965	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FYA90_RS06970	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FYA90_RS06975	COG0583	DNA-binding transcription factor activity
FYA90_RS06985	COG1024	Enoyl-CoA hydratase
FYA90_RS06995	COG1960	acyl-CoA dehydrogenase activity
FYA90_RS07000	COG1028	Short-chain dehydrogenase reductase Sdr
FYA90_RS07005	COG1028	Short-chain dehydrogenase reductase Sdr
FYA90_RS07025	COG3181	Tripartite tricarboxylate transporter family receptor
FYA90_RS07030	COG1028	Short-chain dehydrogenase reductase Sdr
FYA90_RS07040	COG3181	Tripartite tricarboxylate transporter family receptor
FYA90_RS07080	COG0583	DNA-binding transcription factor activity
FYA90_RS07085	COG1960	acyl-CoA dehydrogenase activity
FYA90_RS07090	COG3181	Tripartite tricarboxylate transporter family receptor
FYA90_RS07100	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FYA90_RS07125	COG0560	Phosphoserine phosphatase
FYA90_RS07130	COG0583	DNA-binding transcription factor activity
FYA90_RS07140	COG3842	ATPase activity
FYA90_RS07155	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FYA90_RS07215	COG4336	lyase activity
FYA90_RS07230	COG2233	PERMEase
FYA90_RS07270	COG2818	Glycosylase
FYA90_RS07275	COG0727	PFAM Uncharacterised protein family (UPF0153)
FYA90_RS07300	COG0402	S-adenosylhomocysteine deaminase activity
FYA90_RS07310	COG0156	8-amino-7-oxononanoate synthase activity
FYA90_RS07315	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FYA90_RS07365	COG1464	Belongs to the NlpA lipoprotein family
FYA90_RS07370	COG2011	ABC-type metal ion transport system permease component
FYA90_RS07375	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FYA90_RS07380	COG1501	Belongs to the glycosyl hydrolase 31 family
FYA90_RS07385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FYA90_RS07385	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FYA90_RS07390	COG0483	inositol monophosphate 1-phosphatase activity
FYA90_RS07395	COG0318	PFAM AMP-dependent synthetase and ligase
FYA90_RS07400	COG1473	amidohydrolase
FYA90_RS07405	COG0583	DNA-binding transcription factor activity
FYA90_RS07410	COG2855	membrane
FYA90_RS07420	COG2239	Acts as a magnesium transporter
FYA90_RS07435	COG1522	sequence-specific DNA binding
FYA90_RS07475	COG0330	HflC and HflK could
FYA90_RS07480	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FYA90_RS07485	COG1923	regulation of RNA biosynthetic process
FYA90_RS07495	COG1160	GTP binding
FYA90_RS07500	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FYA90_RS07505	COG2976	Protein conserved in bacteria
FYA90_RS07510	COG0124	histidyl-tRNA synthetase
FYA90_RS07525	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FYA90_RS07530	COG0105	UTP biosynthetic process
FYA90_RS07535	COG0525	valine-tRNA ligase activity
FYA90_RS07545	COG0336	Belongs to the RNA methyltransferase TrmD family
FYA90_RS07550	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FYA90_RS07555	COG0228	four-way junction DNA binding
FYA90_RS07560	COG0425	Belongs to the sulfur carrier protein TusA family
FYA90_RS07640	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FYA90_RS07645	COG2076	Multidrug Resistance protein
FYA90_RS07655	COG5285	phytanoyl-CoA dioxygenase
FYA90_RS07660	COG0662	Cupin 2, conserved barrel domain protein
FYA90_RS07685	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FYA90_RS07715	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FYA90_RS07725	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FYA90_RS07730	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FYA90_RS07740	COG1283	sodium-dependent phosphate transmembrane transporter activity
FYA90_RS07745	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FYA90_RS07750	COG0412	Dienelactone hydrolase
FYA90_RS07755	COG0428	transporter
FYA90_RS07775	COG1845	cytochrome c oxidase, subunit III
FYA90_RS07780	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FYA90_RS07790	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FYA90_RS07790	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FYA90_RS07815	COG1942	4-Oxalocrotonate Tautomerase
FYA90_RS07825	COG4176	ABC-type proline glycine betaine transport system permease component
FYA90_RS07845	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FYA90_RS07850	COG2814	Major facilitator Superfamily
FYA90_RS07855	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FYA90_RS07860	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FYA90_RS07885	COG1846	Transcriptional regulator
FYA90_RS07895	COG0495	leucyl-tRNA aminoacylation
FYA90_RS07910	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FYA90_RS07930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYA90_RS07935	COG2274	protein secretion by the type I secretion system
FYA90_RS07980	COG0427	acetyl-CoA hydrolase
FYA90_RS07990	COG1511	domain protein
FYA90_RS07990	COG3264	Mechanosensitive ion channel
FYA90_RS08010	COG2176	DNA-directed DNA polymerase activity
FYA90_RS08030	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FYA90_RS08035	COG3384	dioxygenase
FYA90_RS08050	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FYA90_RS08120	COG4964	Belongs to the GSP D family
FYA90_RS08165	COG1846	Transcriptional regulator
FYA90_RS08200	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FYA90_RS08210	COG2070	2-Nitropropane dioxygenase
FYA90_RS08215	COG2070	2-Nitropropane dioxygenase
FYA90_RS08225	COG2610	gluconate transmembrane transporter activity
FYA90_RS08240	COG1408	metallophosphoesterase
FYA90_RS08245	COG0493	'glutamate synthase
FYA90_RS08245	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FYA90_RS08255	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FYA90_RS08300	COG0583	DNA-binding transcription factor activity
FYA90_RS08315	COG1024	Enoyl-CoA hydratase
FYA90_RS08320	COG2186	Transcriptional regulator
FYA90_RS08325	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYA90_RS08335	COG0833	amino acid
FYA90_RS08345	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FYA90_RS08370	COG5265	(ABC) transporter
FYA90_RS08415	COG1971	Probably functions as a manganese efflux pump
FYA90_RS08420	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FYA90_RS08435	COG2814	Major facilitator Superfamily
FYA90_RS08460	COG4608	Belongs to the ABC transporter superfamily
FYA90_RS08480	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FYA90_RS08490	COG3383	formate dehydrogenase (NAD+) activity
FYA90_RS08505	COG0747	negative chemotaxis
FYA90_RS08515	COG0625	glutathione transferase activity
FYA90_RS08545	COG1595	DNA-templated transcription, initiation
FYA90_RS08570	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FYA90_RS08585	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FYA90_RS08590	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FYA90_RS08615	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYA90_RS08655	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FYA90_RS08660	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FYA90_RS08665	COG1116	anion transmembrane transporter activity
FYA90_RS08675	COG3585	molybdate ion transport
FYA90_RS08735	COG0583	DNA-binding transcription factor activity
FYA90_RS08740	COG4948	Mandelate Racemase Muconate Lactonizing
FYA90_RS08775	COG3181	Tripartite tricarboxylate transporter family receptor
FYA90_RS08810	COG4177	L-phenylalanine transmembrane transporter activity
FYA90_RS08835	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FYA90_RS08850	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FYA90_RS08855	COG1538	Outer membrane efflux protein
FYA90_RS08860	COG1136	(ABC) transporter
FYA90_RS08860	COG0577	efflux transmembrane transporter activity
FYA90_RS08865	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYA90_RS08880	COG0259	pyridoxamine-phosphate oxidase activity
FYA90_RS08885	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FYA90_RS08890	COG0579	oxidoreductase
FYA90_RS08910	COG3181	Tripartite tricarboxylate transporter family receptor
FYA90_RS08920	COG0114	fumarate hydratase activity
FYA90_RS08925	COG0802	atpase or kinase
FYA90_RS08930	COG0860	N-Acetylmuramoyl-L-alanine amidase
FYA90_RS08935	COG0586	Pfam SNARE associated Golgi protein
FYA90_RS08940	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FYA90_RS08945	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FYA90_RS08950	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FYA90_RS08965	COG0617	tRNA 3'-terminal CCA addition
FYA90_RS09000	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
FYA90_RS09010	COG1024	Enoyl-CoA hydratase
FYA90_RS09020	COG2188	Transcriptional regulator
FYA90_RS09025	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FYA90_RS09040	COG0752	glycyl-tRNA synthetase alpha subunit
FYA90_RS09045	COG0751	glycine-tRNA ligase activity
FYA90_RS09050	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FYA90_RS09055	COG0204	Acyl-transferase
FYA90_RS09085	COG0242	peptide deformylase activity
FYA90_RS09095	COG0700	Nucleoside recognition
FYA90_RS09100	COG0469	pyruvate kinase activity
FYA90_RS09105	COG1929	Belongs to the glycerate kinase type-1 family
FYA90_RS09115	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FYA90_RS09120	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FYA90_RS09125	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FYA90_RS09135	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FYA90_RS09145	COG2154	pterin-4-alpha-carbinolamine dehydratase
FYA90_RS09150	COG2885	chlorophyll binding
FYA90_RS09170	COG3181	Tripartite tricarboxylate transporter family receptor
FYA90_RS09195	COG0288	reversible hydration of carbon dioxide
FYA90_RS09225	COG4829	muconolactone delta-isomerase
FYA90_RS09230	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FYA90_RS09240	COG1414	Transcriptional regulator
FYA90_RS09245	COG1028	Short-chain dehydrogenase reductase Sdr
FYA90_RS09250	COG2031	fatty acid transporter
FYA90_RS09255	COG1250	3-hydroxyacyl-CoA dehydrogenase
FYA90_RS09265	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FYA90_RS09270	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FYA90_RS09285	COG0129	dihydroxy-acid dehydratase activity
FYA90_RS09315	COG4106	trans-aconitate 2-methyltransferase activity
FYA90_RS09330	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FYA90_RS09370	COG0163	prenyltransferase activity
FYA90_RS09375	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FYA90_RS09380	COG2890	protein-(glutamine-N5) methyltransferase activity
FYA90_RS09385	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FYA90_RS09390	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FYA90_RS09405	COG3712	iron ion homeostasis
FYA90_RS09435	COG0659	secondary active sulfate transmembrane transporter activity
FYA90_RS09455	COG1028	Short-chain dehydrogenase reductase Sdr
FYA90_RS09465	COG4774	siderophore transport
FYA90_RS09475	COG1595	DNA-templated transcription, initiation
FYA90_RS09495	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FYA90_RS09500	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FYA90_RS09505	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FYA90_RS09510	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FYA90_RS09530	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FYA90_RS09530	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FYA90_RS09535	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FYA90_RS09550	COG0583	DNA-binding transcription factor activity
FYA90_RS09555	COG0861	Integral membrane protein TerC family
FYA90_RS09570	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FYA90_RS09575	COG0793	Belongs to the peptidase S41A family
FYA90_RS09580	COG4942	peptidase
FYA90_RS09585	COG0588	phosphoglycerate mutase activity
FYA90_RS09595	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FYA90_RS09600	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FYA90_RS09605	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FYA90_RS09610	COG3181	Tripartite tricarboxylate transporter family receptor
FYA90_RS09625	COG2226	methyltransferase
FYA90_RS09630	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
FYA90_RS09635	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FYA90_RS09645	COG2204	response regulator
FYA90_RS09650	COG5000	phosphorelay sensor kinase activity
FYA90_RS09660	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FYA90_RS09660	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FYA90_RS09695	COG2188	Transcriptional regulator
FYA90_RS09710	COG0583	DNA-binding transcription factor activity
FYA90_RS09715	COG1012	belongs to the aldehyde dehydrogenase family
FYA90_RS09735	COG0546	phosphoglycolate phosphatase activity
FYA90_RS09750	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FYA90_RS09755	COG0242	peptide deformylase activity
FYA90_RS09765	COG1522	sequence-specific DNA binding
FYA90_RS09770	COG2879	small protein
FYA90_RS09775	COG1966	Carbon starvation protein
FYA90_RS09805	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYA90_RS09815	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FYA90_RS09820	COG3181	Tripartite tricarboxylate transporter family receptor
FYA90_RS09885	COG1172	Belongs to the binding-protein-dependent transport system permease family
FYA90_RS09920	COG0640	Transcriptional regulator
FYA90_RS09960	COG0735	belongs to the Fur family
FYA90_RS09965	COG2207	Transcriptional regulator
FYA90_RS09970	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FYA90_RS09975	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FYA90_RS10005	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FYA90_RS10020	COG1305	Transglutaminase-like
FYA90_RS10060	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FYA90_RS10065	COG1950	PFAM Membrane protein of
FYA90_RS10090	COG0024	Methionine aminopeptidase
FYA90_RS10095	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FYA90_RS10105	COG1560	Kdo2-lipid A biosynthetic process
FYA90_RS10110	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FYA90_RS10160	COG0523	cobalamin synthesis protein
FYA90_RS10175	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FYA90_RS10185	COG2096	Adenosyltransferase
FYA90_RS10190	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FYA90_RS10195	COG0321	lipoyl(octanoyl) transferase activity
FYA90_RS10205	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FYA90_RS10210	COG1686	Belongs to the peptidase S11 family
FYA90_RS10235	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FYA90_RS10245	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FYA90_RS10255	COG0859	PFAM glycosyl transferase family 9
FYA90_RS10310	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FYA90_RS10340	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FYA90_RS10345	COG1956	GAF domain-containing protein
FYA90_RS10350	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FYA90_RS10365	COG2186	Transcriptional regulator
FYA90_RS10370	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FYA90_RS10425	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FYA90_RS10430	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FYA90_RS10465	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FYA90_RS10475	COG1028	Short-chain dehydrogenase reductase Sdr
FYA90_RS10480	COG1012	belongs to the aldehyde dehydrogenase family
FYA90_RS10505	COG1522	sequence-specific DNA binding
FYA90_RS10510	COG3781	membrane
FYA90_RS10550	COG2200	EAL domain
FYA90_RS10560	COG0592	DNA-directed DNA polymerase activity
FYA90_RS10570	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FYA90_RS10575	COG0594	ribonuclease P activity
FYA90_RS10580	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FYA90_RS10585	COG0706	membrane insertase activity
FYA90_RS10590	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FYA90_RS10600	COG4608	Belongs to the ABC transporter superfamily
FYA90_RS10605	COG0444	Belongs to the ABC transporter superfamily
FYA90_RS10610	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FYA90_RS10615	COG0601	transmembrane transport
FYA90_RS10625	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FYA90_RS10630	COG1505	serine-type exopeptidase activity
FYA90_RS10640	COG0281	malic enzyme
FYA90_RS10640	COG0280	phosphate acetyltransferase
FYA90_RS10670	COG0436	Aminotransferase
FYA90_RS10675	COG1278	Cold shock
FYA90_RS10685	COG0357	Ribosomal RNA small subunit methyltransferase G
FYA90_RS10690	COG1192	Involved in chromosome partitioning
FYA90_RS10695	COG1475	DNA binding
FYA90_RS10700	COG0252	asparaginase activity
FYA90_RS10720	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FYA90_RS10730	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FYA90_RS10745	COG0081	regulation of translation
FYA90_RS10750	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FYA90_RS10755	COG0222	ribosome binding
FYA90_RS10765	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FYA90_RS10800	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FYA90_RS10805	COG0049	tRNA binding
FYA90_RS10810	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FYA90_RS10815	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FYA90_RS10820	COG0051	transcription antitermination factor activity, RNA binding
FYA90_RS10825	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FYA90_RS10830	COG0088	Forms part of the polypeptide exit tunnel
FYA90_RS10835	COG0089	rRNA binding
FYA90_RS10840	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FYA90_RS10845	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FYA90_RS10850	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FYA90_RS10855	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FYA90_RS10860	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FYA90_RS10865	COG0255	Belongs to the universal ribosomal protein uL29 family
FYA90_RS10870	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FYA90_RS10890	COG1129	ABC transporter
FYA90_RS10895	COG0411	ABC transporter
FYA90_RS10925	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FYA90_RS10930	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FYA90_RS10935	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FYA90_RS10940	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FYA90_RS10945	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FYA90_RS10950	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FYA90_RS10955	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FYA90_RS10960	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FYA90_RS10965	COG1841	ribosomal large subunit assembly
FYA90_RS10970	COG0200	Binds to the 23S rRNA
FYA90_RS10975	COG0201	protein transport
FYA90_RS10980	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FYA90_RS10985	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FYA90_RS10990	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FYA90_RS10995	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FYA90_RS11000	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FYA90_RS11005	COG0202	RNA polymerase activity
FYA90_RS11010	COG0203	ribosomal protein L17
FYA90_RS11015	COG0537	adenosine 5'-monophosphoramidase activity
FYA90_RS11020	COG1324	tolerance protein
FYA90_RS11025	COG4232	protein-disulfide reductase activity
FYA90_RS11040	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FYA90_RS11050	COG1333	cytochrome c biogenesis protein
FYA90_RS11055	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FYA90_RS11070	COG1965	Belongs to the frataxin family
FYA90_RS11080	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FYA90_RS11090	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FYA90_RS11110	COG2814	Major facilitator Superfamily
FYA90_RS11135	COG2801	Transposase and inactivated derivatives
FYA90_RS11165	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FYA90_RS11170	COG2922	Belongs to the Smg family
FYA90_RS11175	COG1629	transport
FYA90_RS11185	COG2358	TRAP transporter, solute receptor (TAXI family
FYA90_RS11195	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FYA90_RS11215	COG0183	Belongs to the thiolase family
FYA90_RS11220	COG1960	acyl-CoA dehydrogenase activity
FYA90_RS11245	COG2200	EAL domain
FYA90_RS11250	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FYA90_RS11260	COG0018	arginyl-trna synthetase
FYA90_RS11275	COG0154	amidase activity
FYA90_RS11280	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FYA90_RS11290	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FYA90_RS11300	COG0697	spore germination
FYA90_RS11330	COG2151	metal-sulfur cluster biosynthetic enzyme
FYA90_RS11360	COG3350	monooxygenase activity
FYA90_RS11385	COG1309	transcriptional regulator
FYA90_RS11415	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FYA90_RS11420	COG1280	lysine exporter protein (LysE YggA)
FYA90_RS11425	COG0513	Belongs to the DEAD box helicase family
FYA90_RS11440	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FYA90_RS11470	COG2969	positive regulation of protein catabolic process
FYA90_RS11475	COG0625	glutathione transferase activity
FYA90_RS11480	COG2857	Cytochrome c1
FYA90_RS11485	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FYA90_RS11495	COG1970	mechanosensitive ion channel activity
FYA90_RS11500	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FYA90_RS11505	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FYA90_RS11515	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FYA90_RS11520	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FYA90_RS11530	COG0140	phosphoribosyl-ATP diphosphatase activity
FYA90_RS11535	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FYA90_RS11540	COG0107	imidazoleglycerol-phosphate synthase activity
FYA90_RS11545	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FYA90_RS11555	COG0131	Imidazoleglycerol-phosphate dehydratase
FYA90_RS11565	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FYA90_RS11570	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FYA90_RS11575	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FYA90_RS11580	COG0271	Belongs to the BolA IbaG family
FYA90_RS11585	COG0842	Transport permease protein
FYA90_RS11590	COG1131	(ABC) transporter
FYA90_RS11605	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FYA90_RS11610	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FYA90_RS11615	COG1127	ABC transporter
FYA90_RS11660	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FYA90_RS11680	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FYA90_RS11685	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FYA90_RS11765	COG0109	protoheme IX farnesyltransferase activity
FYA90_RS11770	COG1999	signal sequence binding
FYA90_RS11790	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FYA90_RS11795	COG2814	Major facilitator Superfamily
FYA90_RS11810	COG1522	sequence-specific DNA binding
FYA90_RS11875	COG4948	Mandelate Racemase Muconate Lactonizing
FYA90_RS11890	COG3119	arylsulfatase activity
FYA90_RS11925	COG0402	S-adenosylhomocysteine deaminase activity
FYA90_RS11935	COG1304	FMN binding
FYA90_RS11940	COG1254	Belongs to the acylphosphatase family
FYA90_RS11950	COG3181	Tripartite tricarboxylate transporter family receptor
FYA90_RS11960	COG1414	Transcriptional regulator
FYA90_RS11980	COG0028	Belongs to the TPP enzyme family
FYA90_RS11985	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FYA90_RS11990	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYA90_RS11995	COG1960	acyl-CoA dehydrogenase activity
FYA90_RS12030	COG3181	Tripartite tricarboxylate transporter family receptor
FYA90_RS12035	COG0583	DNA-binding transcription factor activity
FYA90_RS12055	COG2084	Dehydrogenase
FYA90_RS12070	COG1671	Belongs to the UPF0178 family
FYA90_RS12075	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FYA90_RS12085	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FYA90_RS12090	COG0443	Heat shock 70 kDa protein
FYA90_RS12115	COG2169	Transcriptional regulator
FYA90_RS12115	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FYA90_RS12130	COG1683	Conserved Protein
FYA90_RS12135	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FYA90_RS12150	COG1120	ATPase activity
FYA90_RS12155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FYA90_RS12165	COG3720	iron ion transport
FYA90_RS12180	COG3712	iron ion homeostasis
FYA90_RS12185	COG1595	DNA-templated transcription, initiation
FYA90_RS12205	COG1607	acyl-coa hydrolase
FYA90_RS12220	COG0437	4 iron, 4 sulfur cluster binding
FYA90_RS12225	COG2864	formate dehydrogenase
FYA90_RS12275	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FYA90_RS12280	COG0512	Glutamine amidotransferase of anthranilate synthase
FYA90_RS12290	COG0546	phosphoglycolate phosphatase activity
FYA90_RS12295	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FYA90_RS12300	COG2967	ApaG domain
FYA90_RS12305	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FYA90_RS12310	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FYA90_RS12315	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FYA90_RS12320	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FYA90_RS12325	COG0037	tRNA processing
FYA90_RS12345	COG1024	Enoyl-CoA hydratase
FYA90_RS12360	COG0356	it plays a direct role in the translocation of protons across the membrane
FYA90_RS12370	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FYA90_RS12375	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FYA90_RS12380	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FYA90_RS12385	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FYA90_RS12390	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FYA90_RS12410	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FYA90_RS12415	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FYA90_RS12420	COG0210	DNA helicase
FYA90_RS12435	COG4608	Belongs to the ABC transporter superfamily
FYA90_RS12440	COG0444	Belongs to the ABC transporter superfamily
FYA90_RS12445	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FYA90_RS12470	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FYA90_RS12475	COG1024	Enoyl-CoA hydratase
FYA90_RS12480	COG1024	Enoyl-CoA hydratase
FYA90_RS12485	COG2070	2-Nitropropane dioxygenase
FYA90_RS12505	COG1250	3-hydroxyacyl-CoA dehydrogenase
FYA90_RS12525	COG2267	carboxylic ester hydrolase activity
FYA90_RS12545	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FYA90_RS12555	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FYA90_RS12555	COG2813	Specifically methylates the guanine in position
FYA90_RS12565	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FYA90_RS12580	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FYA90_RS12585	COG0708	Exodeoxyribonuclease III
FYA90_RS12590	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FYA90_RS12595	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FYA90_RS12600	COG0154	amidase activity
FYA90_RS12605	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FYA90_RS12610	COG1077	Cell shape determining protein MreB Mrl
FYA90_RS12615	COG1792	Involved in formation and maintenance of cell shape
FYA90_RS12625	COG0768	penicillin binding
FYA90_RS12630	COG0772	Belongs to the SEDS family
FYA90_RS12635	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FYA90_RS12640	COG0471	metal ion transport
FYA90_RS12645	COG1309	transcriptional regulator
FYA90_RS12655	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FYA90_RS12670	COG2823	Periplasmic or secreted lipoprotein
FYA90_RS12675	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FYA90_RS12680	COG0792	nuclease activity
FYA90_RS12700	COG1660	Displays ATPase and GTPase activities
FYA90_RS12715	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FYA90_RS12725	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FYA90_RS12735	COG3181	Tripartite tricarboxylate transporter family receptor
FYA90_RS12745	COG1137	ATPase activity
FYA90_RS12760	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FYA90_RS12770	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FYA90_RS12790	COG1294	oxidase, subunit
FYA90_RS12800	COG4988	ABC transporter
FYA90_RS12805	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FYA90_RS12810	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FYA90_RS12825	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FYA90_RS12830	COG1238	metal cluster binding
FYA90_RS12850	COG1984	allophanate hydrolase subunit 2
FYA90_RS12855	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FYA90_RS12865	COG0583	DNA-binding transcription factor activity
FYA90_RS12880	COG0745	RESPONSE REGULATOR receiver
FYA90_RS12885	COG2226	methyltransferase
FYA90_RS12930	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FYA90_RS12940	COG1028	Short-chain dehydrogenase reductase Sdr
FYA90_RS12960	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FYA90_RS12965	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FYA90_RS12975	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FYA90_RS12995	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FYA90_RS13000	COG1538	Outer membrane efflux protein
FYA90_RS13010	COG0351	phosphomethylpyrimidine kinase
FYA90_RS13015	COG2022	thiamine diphosphate biosynthetic process
FYA90_RS13020	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FYA90_RS13040	COG2226	methyltransferase
FYA90_RS13050	COG1194	a g-specific adenine glycosylase
FYA90_RS13060	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FYA90_RS13065	COG2177	Part of the ABC transporter FtsEX involved in
FYA90_RS13070	COG2884	Cell division ATP-binding protein ftsE
FYA90_RS13075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYA90_RS13085	COG0765	amino acid transport
FYA90_RS13090	COG1126	abc transporter atp-binding protein
FYA90_RS13120	COG0477	Major facilitator Superfamily
FYA90_RS13130	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FYA90_RS13135	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FYA90_RS13150	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FYA90_RS13155	COG0237	dephospho-CoA kinase activity
FYA90_RS13170	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FYA90_RS13185	COG3539	Fimbrial protein
FYA90_RS13190	COG3539	Fimbrial protein
FYA90_RS13205	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FYA90_RS13215	COG1846	Transcriptional regulator
FYA90_RS13285	COG1028	Short-chain dehydrogenase reductase Sdr
FYA90_RS13290	COG1024	Enoyl-CoA hydratase
FYA90_RS13325	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FYA90_RS13330	COG0352	thiamine-phosphate diphosphorylase activity
FYA90_RS13335	COG0351	phosphomethylpyrimidine kinase
FYA90_RS13345	COG1678	Uncharacterized ACR, COG1678
FYA90_RS13350	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FYA90_RS13375	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FYA90_RS13385	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FYA90_RS13390	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FYA90_RS13400	COG0557	exoribonuclease II activity
FYA90_RS13410	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FYA90_RS13415	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FYA90_RS13420	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FYA90_RS13430	COG0439	Biotin carboxylase
FYA90_RS13435	COG2264	protein methyltransferase activity
FYA90_RS13445	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FYA90_RS13520	COG1522	sequence-specific DNA binding
FYA90_RS13535	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FYA90_RS13625	COG3028	Belongs to the UPF0307 family
FYA90_RS13635	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FYA90_RS13640	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FYA90_RS13645	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FYA90_RS13655	COG0316	Belongs to the HesB IscA family
FYA90_RS13675	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FYA90_RS13685	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FYA90_RS13690	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FYA90_RS13705	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FYA90_RS13705	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FYA90_RS13720	COG2718	Belongs to the UPF0229 family
FYA90_RS13725	COG2719	SpoVR family
FYA90_RS13785	COG0165	Argininosuccinate lyase
FYA90_RS13790	COG0589	response to stress
FYA90_RS13800	COG2816	NAD+ diphosphatase activity
FYA90_RS13805	COG4993	Dehydrogenase
FYA90_RS13830	COG3181	Tripartite tricarboxylate transporter family receptor
FYA90_RS13835	COG2979	Protein of unknown function (DUF533)
FYA90_RS13840	COG4206	TonB-dependent receptor
FYA90_RS13855	COG0741	lytic transglycosylase activity
FYA90_RS13855	COG1388	LysM domain
FYA90_RS13860	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FYA90_RS13865	COG2226	methyltransferase
FYA90_RS13870	COG0328	RNA-DNA hybrid ribonuclease activity
FYA90_RS13895	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FYA90_RS13915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYA90_RS13920	COG1129	ABC transporter
FYA90_RS13920	COG0842	Transport permease protein
FYA90_RS13925	COG0842	Transport permease protein
FYA90_RS13950	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FYA90_RS13965	COG1073	alpha beta
FYA90_RS14005	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FYA90_RS14035	COG0823	Involved in the tonB-independent uptake of proteins
FYA90_RS14045	COG0848	biopolymer transport protein
FYA90_RS14050	COG0811	peptide transport
FYA90_RS14055	COG0824	Thioesterase
FYA90_RS14060	COG0442	prolyl-tRNA aminoacylation
FYA90_RS14105	COG2084	Dehydrogenase
FYA90_RS14150	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FYA90_RS14155	COG4654	Cytochrome c, class I
FYA90_RS14160	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FYA90_RS14225	COG1473	amidohydrolase
FYA90_RS14230	COG0418	dihydroorotase activity
FYA90_RS14235	COG0488	(ABC) transporter
FYA90_RS14245	COG2001	Belongs to the MraZ family
FYA90_RS14250	COG0275	rRNA processing
FYA90_RS14255	COG3116	cell division
FYA90_RS14290	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FYA90_RS14295	COG1181	Belongs to the D-alanine--D-alanine ligase family
FYA90_RS14300	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FYA90_RS14315	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FYA90_RS14330	COG0739	heme binding
FYA90_RS14335	COG0653	protein targeting
FYA90_RS14365	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FYA90_RS14375	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FYA90_RS14425	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FYA90_RS14440	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
FYA90_RS14455	COG0583	DNA-binding transcription factor activity
FYA90_RS14465	COG3181	Tripartite tricarboxylate transporter family receptor
FYA90_RS14470	COG2084	Dehydrogenase
FYA90_RS14490	COG0671	phosphoesterase, PA-phosphatase related
FYA90_RS14510	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FYA90_RS14515	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FYA90_RS14520	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FYA90_RS14525	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FYA90_RS14530	COG0649	NAD binding
FYA90_RS14535	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FYA90_RS14545	COG1034	ATP synthesis coupled electron transport
FYA90_RS14550	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FYA90_RS14555	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FYA90_RS14565	COG0713	ATP synthesis coupled electron transport
FYA90_RS14580	COG1007	ATP synthesis coupled electron transport
FYA90_RS14590	COG0560	Phosphoserine phosphatase
FYA90_RS14595	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FYA90_RS14600	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FYA90_RS14605	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FYA90_RS14620	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FYA90_RS14625	COG0450	alkyl hydroperoxide reductase
FYA90_RS14645	COG1214	PFAM Peptidase M22, glycoprotease
FYA90_RS14650	COG1573	uracil-dna glycosylase
FYA90_RS14655	COG0477	Major facilitator Superfamily
FYA90_RS14660	COG1196	nuclear chromosome segregation
FYA90_RS14670	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FYA90_RS14675	COG1126	abc transporter atp-binding protein
FYA90_RS14680	COG0765	amino acid transport
FYA90_RS14685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYA90_RS14690	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FYA90_RS14695	COG2917	probably involved in intracellular septation
FYA90_RS14700	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FYA90_RS14705	COG1122	ATPase activity
FYA90_RS14710	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FYA90_RS14715	COG1268	BioY protein
FYA90_RS14745	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FYA90_RS14775	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FYA90_RS14780	COG2878	Part of a membrane complex involved in electron transport
FYA90_RS14800	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FYA90_RS14805	COG0251	oxidation-reduction process
FYA90_RS14815	COG3228	Belongs to the MtfA family
FYA90_RS14820	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FYA90_RS14830	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FYA90_RS14840	COG0159	tryptophan synthase activity
FYA90_RS14845	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FYA90_RS14870	COG0564	pseudouridine synthase activity
FYA90_RS14875	COG0546	phosphoglycolate phosphatase activity
FYA90_RS14885	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FYA90_RS14890	COG3023	N-Acetylmuramoyl-L-alanine amidase
FYA90_RS14900	COG0424	maF-like protein
FYA90_RS14910	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FYA90_RS14920	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FYA90_RS14935	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FYA90_RS14940	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FYA90_RS14965	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FYA90_RS15000	COG0481	GTPase activity
FYA90_RS15005	COG0681	Belongs to the peptidase S26 family
FYA90_RS15010	COG0571	ribonuclease III activity
FYA90_RS15015	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FYA90_RS15020	COG1381	Involved in DNA repair and RecF pathway recombination
FYA90_RS15040	COG0670	Belongs to the BI1 family
FYA90_RS15055	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FYA90_RS15080	COG0583	DNA-binding transcription factor activity
FYA90_RS15095	COG0791	NLP P60 protein
FYA90_RS15100	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FYA90_RS15105	COG3193	protein, possibly involved in utilization of glycolate and propanediol
FYA90_RS15115	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FYA90_RS15135	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FYA90_RS15170	COG1446	asparaginase
FYA90_RS15175	COG4172	Belongs to the ABC transporter superfamily
FYA90_RS15180	COG0747	negative chemotaxis
FYA90_RS15185	COG0601	transmembrane transport
FYA90_RS15210	COG0504	CTP synthase activity
FYA90_RS15235	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FYA90_RS15250	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FYA90_RS15290	COG1981	membrane
FYA90_RS15315	COG2188	Transcriptional regulator
FYA90_RS15320	COG2009	succinate dehydrogenase
FYA90_RS15325	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FYA90_RS15330	COG1053	succinate dehydrogenase
FYA90_RS15335	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FYA90_RS15340	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FYA90_RS15345	COG0372	Belongs to the citrate synthase family
FYA90_RS15355	COG0583	DNA-binding transcription factor activity
FYA90_RS15360	COG3842	ATPase activity
FYA90_RS15370	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FYA90_RS15375	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FYA90_RS15385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FYA90_RS15395	COG3128	pkhd-type hydroxylase
FYA90_RS15410	COG0281	malic enzyme
FYA90_RS15410	COG0280	phosphate acetyltransferase
FYA90_RS15425	COG0567	Dehydrogenase, E1 component
FYA90_RS15430	COG0508	dehydrogenase complex catalyzes the overall conversion of
FYA90_RS15435	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FYA90_RS15440	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FYA90_RS15445	COG1595	DNA-templated transcription, initiation
FYA90_RS15455	COG4774	siderophore transport
FYA90_RS15480	COG2183	response to ionizing radiation
FYA90_RS15485	COG1199	ATP-dependent helicase activity
FYA90_RS15495	COG0564	pseudouridine synthase activity
FYA90_RS15505	COG3243	poly(R)-hydroxyalkanoic acid synthase
FYA90_RS15510	COG1028	Short-chain dehydrogenase reductase Sdr
FYA90_RS15515	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
FYA90_RS15530	COG0672	)-iron permease
FYA90_RS15545	COG2823	Periplasmic or secreted lipoprotein
FYA90_RS15565	COG3237	CsbD-like
FYA90_RS15570	COG3038	cytochrome b561
FYA90_RS15585	COG1132	(ABC) transporter
FYA90_RS15600	COG2833	Protein of unknown function (DUF455)
FYA90_RS15605	COG2951	lytic endotransglycosylase activity
FYA90_RS15630	COG0586	Pfam SNARE associated Golgi protein
FYA90_RS15685	COG0165	Argininosuccinate lyase
FYA90_RS15705	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FYA90_RS15720	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FYA90_RS15725	COG1605	Chorismate mutase
FYA90_RS15725	COG0077	Prephenate dehydratase
FYA90_RS15730	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FYA90_RS15745	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FYA90_RS15765	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FYA90_RS15770	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FYA90_RS15775	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FYA90_RS15780	COG0587	DNA-directed DNA polymerase activity
FYA90_RS15790	COG2951	lytic endotransglycosylase activity
FYA90_RS15795	COG0123	including yeast histone deacetylase and acetoin utilization protein
FYA90_RS15815	COG1960	acyl-CoA dehydrogenase activity
FYA90_RS15820	COG0450	alkyl hydroperoxide reductase
FYA90_RS15825	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FYA90_RS15830	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FYA90_RS15835	COG4208	sulfate ABC transporter
FYA90_RS15840	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FYA90_RS15845	COG0175	sulfate reduction
FYA90_RS15870	COG0335	large ribosomal subunit rRNA binding
FYA90_RS15885	COG3622	Belongs to the hyi family
FYA90_RS15890	COG1162	GTPase activity
FYA90_RS15895	COG0501	Belongs to the peptidase M48B family
FYA90_RS15900	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FYA90_RS15905	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FYA90_RS15910	COG3327	negative regulation of DNA-templated transcription, initiation
FYA90_RS15915	COG3396	Phenylacetate-CoA oxygenase
FYA90_RS15920	COG3460	Phenylacetate-CoA oxygenase
FYA90_RS15925	COG3396	Phenylacetate-CoA oxygenase
FYA90_RS15930	COG2151	metal-sulfur cluster biosynthetic enzyme
FYA90_RS15935	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FYA90_RS15940	COG1012	belongs to the aldehyde dehydrogenase family
FYA90_RS15945	COG1024	Enoyl-CoA hydratase
FYA90_RS15950	COG2050	protein possibly involved in aromatic compounds catabolism
FYA90_RS15980	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FYA90_RS15980	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FYA90_RS15990	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FYA90_RS15995	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FYA90_RS16000	COG2346	COG2346, Truncated hemoglobins
FYA90_RS16005	COG3642	lipopolysaccharide core region biosynthetic process
FYA90_RS16015	COG3842	ATPase activity
FYA90_RS16020	COG1176	ABC-type spermidine putrescine transport system, permease component I
FYA90_RS16025	COG1177	transmembrane transport
FYA90_RS16045	COG1322	Protein conserved in bacteria
FYA90_RS16055	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FYA90_RS16060	COG0704	Plays a role in the regulation of phosphate uptake
FYA90_RS16065	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FYA90_RS16070	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FYA90_RS16070	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FYA90_RS16075	COG1643	Atp-dependent helicase
FYA90_RS16090	COG0438	transferase activity, transferring glycosyl groups
FYA90_RS16095	COG0726	polysaccharide deacetylase
FYA90_RS16100	COG0463	Glycosyl transferase, family 2
FYA90_RS16135	COG1132	(ABC) transporter
FYA90_RS16155	COG0501	Belongs to the peptidase M48B family
FYA90_RS16200	COG1722	exodeoxyribonuclease VII activity
FYA90_RS16205	COG0142	geranyltranstransferase activity
FYA90_RS16215	COG1469	GTP cyclohydrolase I activity
FYA90_RS16220	COG0360	Binds together with S18 to 16S ribosomal RNA
FYA90_RS16225	COG2965	DNA replication, synthesis of RNA primer
FYA90_RS16230	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FYA90_RS16235	COG0359	binds to the 23S rRNA
FYA90_RS16245	COG0305	Participates in initiation and elongation during chromosome replication
FYA90_RS16255	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FYA90_RS16260	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FYA90_RS16265	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FYA90_RS16270	COG3737	Protein of unknown function (DUF498/DUF598)
FYA90_RS16275	COG0436	Aminotransferase
FYA90_RS16300	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FYA90_RS16305	COG0308	aminopeptidase N
FYA90_RS16320	COG0312	modulator of DNA gyrase
FYA90_RS16325	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FYA90_RS16345	COG0277	FAD linked oxidase domain protein
FYA90_RS16350	COG0277	FAD linked oxidase domain protein
FYA90_RS16355	COG0247	lactate metabolic process
FYA90_RS16395	COG0583	DNA-binding transcription factor activity
FYA90_RS16400	COG0482	sulfurtransferase activity
FYA90_RS16405	COG0730	response to heat
FYA90_RS16410	COG0625	glutathione transferase activity
FYA90_RS16420	COG3909	cytochrome
FYA90_RS16455	COG3706	GGDEF domain
FYA90_RS16470	COG2826	transposase and inactivated derivatives, IS30 family
FYA90_RS16490	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
FYA90_RS16515	COG0069	glutamate synthase activity
FYA90_RS16520	COG2391	methyltransferase activity
FYA90_RS16525	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FYA90_RS16555	COG0557	exoribonuclease II activity
FYA90_RS16560	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FYA90_RS16565	COG2873	o-acetylhomoserine
FYA90_RS16570	COG0776	regulation of translation
FYA90_RS16600	COG0642	Histidine kinase
FYA90_RS16605	COG3158	transport of potassium into the cell
FYA90_RS16630	COG0137	argininosuccinate synthase activity
FYA90_RS16635	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FYA90_RS16660	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FYA90_RS16675	COG2186	Transcriptional regulator
FYA90_RS16705	COG3836	Belongs to the HpcH HpaI aldolase family
FYA90_RS16710	COG0268	Binds directly to 16S ribosomal RNA
FYA90_RS16755	COG0728	peptidoglycan biosynthetic process
FYA90_RS16770	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FYA90_RS16775	COG2835	tetraacyldisaccharide 4'-kinase activity
FYA90_RS16785	COG0848	biopolymer transport protein
FYA90_RS16790	COG0811	peptide transport
FYA90_RS16795	COG1570	exodeoxyribonuclease VII activity
FYA90_RS16800	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FYA90_RS16810	COG0038	chloride channel
FYA90_RS16815	COG0183	Belongs to the thiolase family
FYA90_RS16825	COG1278	Cold shock
FYA90_RS16830	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FYA90_RS16855	COG3008	intermembrane lipid transfer
FYA90_RS16895	COG0004	ammonium transporteR
FYA90_RS16900	COG0347	Belongs to the P(II) protein family
FYA90_RS16940	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FYA90_RS16945	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FYA90_RS16950	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FYA90_RS16960	COG0776	regulation of translation
FYA90_RS16990	COG1802	Transcriptional regulator
FYA90_RS16995	COG3181	Tripartite tricarboxylate transporter family receptor
FYA90_RS17015	COG1278	Cold shock
FYA90_RS17045	COG1522	sequence-specific DNA binding
FYA90_RS17095	COG5265	(ABC) transporter
FYA90_RS17115	COG0656	L-ascorbic acid biosynthetic process
FYA90_RS17120	COG0667	Aldo Keto reductase
FYA90_RS17135	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FYA90_RS17180	COG1610	YqeY-like protein
FYA90_RS17200	COG3246	L-lysine catabolic process to acetate
FYA90_RS17215	COG0318	PFAM AMP-dependent synthetase and ligase
FYA90_RS17230	COG0183	Belongs to the thiolase family
FYA90_RS17245	COG1250	3-hydroxyacyl-CoA dehydrogenase
FYA90_RS17245	COG1024	Enoyl-CoA hydratase
FYA90_RS17250	COG0183	Belongs to the thiolase family
FYA90_RS17255	COG1960	acyl-CoA dehydrogenase activity
FYA90_RS17275	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FYA90_RS17280	COG0483	inositol monophosphate 1-phosphatase activity
FYA90_RS17285	COG1012	belongs to the aldehyde dehydrogenase family
FYA90_RS17290	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FYA90_RS17305	COG0210	DNA helicase
FYA90_RS17310	COG0598	Magnesium transport protein CorA
FYA90_RS17320	COG0747	negative chemotaxis
FYA90_RS17325	COG0601	transmembrane transport
FYA90_RS17330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FYA90_RS17335	COG4172	Belongs to the ABC transporter superfamily
FYA90_RS17355	COG1346	cytolysis
FYA90_RS17370	COG0783	Belongs to the Dps family
FYA90_RS17390	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
FYA90_RS17400	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FYA90_RS17405	COG1845	cytochrome c oxidase, subunit III
FYA90_RS17410	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FYA90_RS17455	COG1666	GTP binding
FYA90_RS17480	COG1028	Short-chain dehydrogenase reductase Sdr
FYA90_RS17485	COG5006	permease, DMT superfamily
FYA90_RS17510	COG2264	protein methyltransferase activity
FYA90_RS17545	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FYA90_RS17550	COG0746	molybdenum cofactor guanylyltransferase activity
FYA90_RS17555	COG0303	'Molybdopterin
FYA90_RS17560	COG0521	Mo-molybdopterin cofactor biosynthetic process
FYA90_RS17565	COG0314	molybdopterin synthase activity
FYA90_RS17575	COG0315	cyclic pyranopterin monophosphate synthase activity
FYA90_RS17580	COG0412	Dienelactone hydrolase
FYA90_RS17590	COG0678	peroxiredoxin activity
FYA90_RS17605	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FYA90_RS17615	COG0542	response to heat
FYA90_RS17630	COG1477	protein flavinylation
FYA90_RS17655	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FYA90_RS17660	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
FYA90_RS17660	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
FYA90_RS17665	COG1562	ergosterol biosynthetic process
FYA90_RS17670	COG1562	ergosterol biosynthetic process
FYA90_RS17675	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FYA90_RS17715	COG0254	rRNA binding
FYA90_RS17725	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FYA90_RS17730	COG2003	Belongs to the UPF0758 family
FYA90_RS17740	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FYA90_RS17745	COG0625	glutathione transferase activity
FYA90_RS17765	COG0523	cobalamin synthesis protein
FYA90_RS17775	COG0583	DNA-binding transcription factor activity
FYA90_RS17785	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FYA90_RS17795	COG0779	Required for maturation of 30S ribosomal subunits
FYA90_RS17800	COG0195	Participates in both transcription termination and antitermination
FYA90_RS17800	COG2251	uridine kinase activity
FYA90_RS17805	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FYA90_RS17810	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FYA90_RS17815	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FYA90_RS17820	COG1217	gtp-binding protein TYPA
FYA90_RS17835	COG1802	Transcriptional regulator
FYA90_RS17845	COG1024	Enoyl-CoA hydratase
FYA90_RS17850	COG0318	PFAM AMP-dependent synthetase and ligase
FYA90_RS17860	COG2032	superoxide dismutase activity
FYA90_RS17875	COG4120	Belongs to the binding-protein-dependent transport system permease family
FYA90_RS17880	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FYA90_RS17885	COG0725	ABC transporter, periplasmic molybdate-binding protein
FYA90_RS17890	COG4149	molybdate abc transporter
FYA90_RS17920	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYA90_RS17925	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYA90_RS17940	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FYA90_RS17945	COG0736	holo-[acyl-carrier-protein] synthase activity
FYA90_RS17950	COG1472	Belongs to the glycosyl hydrolase 3 family
FYA90_RS17955	COG0322	excinuclease ABC activity
FYA90_RS17960	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FYA90_RS17970	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FYA90_RS17970	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FYA90_RS17975	COG2224	Isocitrate lyase
FYA90_RS17980	COG1846	Transcriptional regulator
FYA90_RS17985	COG1764	response to oxidative stress
FYA90_RS17990	COG1131	(ABC) transporter
FYA90_RS18000	COG0628	permease
FYA90_RS18025	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
FYA90_RS18035	COG2814	Major facilitator Superfamily
FYA90_RS18055	COG3015	lipoprotein NlpE involved in copper resistance
FYA90_RS18065	COG3530	Putative quorum-sensing-regulated virulence factor
FYA90_RS18080	COG0494	nUDIX hydrolase
FYA90_RS18090	COG0697	spore germination
FYA90_RS18095	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FYA90_RS18120	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FYA90_RS18125	COG1702	phosphate starvation-inducible protein PhoH
FYA90_RS18130	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FYA90_RS18135	COG4535	Mg2 and Co2 transporter CorC
FYA90_RS18145	COG0667	Aldo Keto reductase
FYA90_RS18165	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FYA90_RS18170	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FYA90_RS18180	COG0343	queuine tRNA-ribosyltransferase activity
FYA90_RS18185	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FYA90_RS18190	COG2027	D-alanyl-D-alanine carboxypeptidase
FYA90_RS18195	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FYA90_RS18200	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FYA90_RS18200	COG1648	precorrin-2 dehydrogenase activity
FYA90_RS18210	COG4575	ribosome binding
FYA90_RS18235	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FYA90_RS18240	COG0741	lytic transglycosylase activity
FYA90_RS18255	COG0280	phosphate acetyltransferase
FYA90_RS18255	COG0281	malic enzyme
FYA90_RS18275	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FYA90_RS18280	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FYA90_RS18285	COG0126	phosphoglycerate kinase activity
FYA90_RS18300	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FYA90_RS18315	COG0625	glutathione transferase activity
FYA90_RS18335	COG0789	Transcriptional regulator