locus-tag	class	description
FYB57_RS00005	COG0445	tRNA wobble uridine modification
FYB57_RS00010	COG0357	Ribosomal RNA small subunit methyltransferase G
FYB57_RS00015	COG1192	Involved in chromosome partitioning
FYB57_RS00020	COG1475	DNA binding
FYB57_RS00025	COG0252	asparaginase activity
FYB57_RS00045	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FYB57_RS00055	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FYB57_RS00065	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FYB57_RS00070	COG0081	regulation of translation
FYB57_RS00075	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FYB57_RS00080	COG0222	ribosome binding
FYB57_RS00085	COG0085	RNA polymerase activity
FYB57_RS00090	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FYB57_RS00125	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FYB57_RS00130	COG0049	tRNA binding
FYB57_RS00135	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FYB57_RS00140	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FYB57_RS00145	COG0051	transcription antitermination factor activity, RNA binding
FYB57_RS00150	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FYB57_RS00155	COG0088	Forms part of the polypeptide exit tunnel
FYB57_RS00160	COG0089	rRNA binding
FYB57_RS00165	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FYB57_RS00170	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FYB57_RS00175	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FYB57_RS00180	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FYB57_RS00185	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FYB57_RS00190	COG0255	Belongs to the universal ribosomal protein uL29 family
FYB57_RS00195	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FYB57_RS00205	COG4177	L-phenylalanine transmembrane transporter activity
FYB57_RS00215	COG1129	ABC transporter
FYB57_RS00220	COG0411	ABC transporter
FYB57_RS00250	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FYB57_RS00255	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FYB57_RS00260	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FYB57_RS00265	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FYB57_RS00270	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FYB57_RS00275	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FYB57_RS00280	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FYB57_RS00285	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FYB57_RS00290	COG1841	ribosomal large subunit assembly
FYB57_RS00295	COG0200	Binds to the 23S rRNA
FYB57_RS00300	COG0201	protein transport
FYB57_RS00305	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FYB57_RS00310	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FYB57_RS00315	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FYB57_RS00320	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FYB57_RS00325	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FYB57_RS00330	COG0202	RNA polymerase activity
FYB57_RS00335	COG0203	ribosomal protein L17
FYB57_RS00340	COG0537	adenosine 5'-monophosphoramidase activity
FYB57_RS00345	COG1324	tolerance protein
FYB57_RS00350	COG4232	protein-disulfide reductase activity
FYB57_RS00365	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FYB57_RS00375	COG1333	cytochrome c biogenesis protein
FYB57_RS00380	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FYB57_RS00395	COG1965	Belongs to the frataxin family
FYB57_RS00405	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FYB57_RS00410	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FYB57_RS00415	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FYB57_RS00435	COG2814	Major facilitator Superfamily
FYB57_RS00460	COG2801	Transposase and inactivated derivatives
FYB57_RS00490	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FYB57_RS00495	COG2922	Belongs to the Smg family
FYB57_RS00500	COG1629	transport
FYB57_RS00510	COG2358	TRAP transporter, solute receptor (TAXI family
FYB57_RS00520	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FYB57_RS00535	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FYB57_RS00540	COG0183	Belongs to the thiolase family
FYB57_RS00545	COG1960	acyl-CoA dehydrogenase activity
FYB57_RS00570	COG2200	EAL domain
FYB57_RS00575	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FYB57_RS00585	COG0018	arginyl-trna synthetase
FYB57_RS00600	COG0154	amidase activity
FYB57_RS00605	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FYB57_RS00615	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FYB57_RS00625	COG0697	spore germination
FYB57_RS00685	COG3350	monooxygenase activity
FYB57_RS00710	COG1309	transcriptional regulator
FYB57_RS00740	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FYB57_RS00745	COG1280	lysine exporter protein (LysE YggA)
FYB57_RS00750	COG0513	Belongs to the DEAD box helicase family
FYB57_RS00760	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
FYB57_RS00765	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FYB57_RS00795	COG2969	positive regulation of protein catabolic process
FYB57_RS00800	COG0625	glutathione transferase activity
FYB57_RS00805	COG2857	Cytochrome c1
FYB57_RS00810	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FYB57_RS00815	COG0723	plastoquinol--plastocyanin reductase activity
FYB57_RS00820	COG1970	mechanosensitive ion channel activity
FYB57_RS00825	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FYB57_RS00830	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FYB57_RS00840	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FYB57_RS00845	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FYB57_RS00855	COG0140	phosphoribosyl-ATP diphosphatase activity
FYB57_RS00860	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FYB57_RS00865	COG0107	imidazoleglycerol-phosphate synthase activity
FYB57_RS00870	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FYB57_RS00880	COG0131	Imidazoleglycerol-phosphate dehydratase
FYB57_RS00885	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FYB57_RS00890	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FYB57_RS00895	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FYB57_RS00900	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FYB57_RS00910	COG0842	Transport permease protein
FYB57_RS00915	COG1131	(ABC) transporter
FYB57_RS00930	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FYB57_RS00935	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FYB57_RS00940	COG1127	ABC transporter
FYB57_RS00960	COG0067	glutamate synthase
FYB57_RS00960	COG0070	glutamate synthase
FYB57_RS00960	COG0069	glutamate synthase activity
FYB57_RS00985	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FYB57_RS01005	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FYB57_RS01010	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FYB57_RS01055	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FYB57_RS01090	COG0109	protoheme IX farnesyltransferase activity
FYB57_RS01095	COG1999	signal sequence binding
FYB57_RS01115	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FYB57_RS01120	COG2814	Major facilitator Superfamily
FYB57_RS01135	COG1522	sequence-specific DNA binding
FYB57_RS01200	COG4948	Mandelate Racemase Muconate Lactonizing
FYB57_RS01215	COG3119	arylsulfatase activity
FYB57_RS01250	COG0402	S-adenosylhomocysteine deaminase activity
FYB57_RS01260	COG1304	FMN binding
FYB57_RS01265	COG1254	Belongs to the acylphosphatase family
FYB57_RS01275	COG3181	Tripartite tricarboxylate transporter family receptor
FYB57_RS01285	COG1414	Transcriptional regulator
FYB57_RS01305	COG0028	Belongs to the TPP enzyme family
FYB57_RS01310	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FYB57_RS01315	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYB57_RS01320	COG1960	acyl-CoA dehydrogenase activity
FYB57_RS01355	COG3181	Tripartite tricarboxylate transporter family receptor
FYB57_RS01360	COG0583	DNA-binding transcription factor activity
FYB57_RS01375	COG0129	dihydroxy-acid dehydratase activity
FYB57_RS01380	COG2084	Dehydrogenase
FYB57_RS01395	COG1671	Belongs to the UPF0178 family
FYB57_RS01400	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FYB57_RS01410	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FYB57_RS01415	COG0443	Heat shock 70 kDa protein
FYB57_RS01440	COG2169	Transcriptional regulator
FYB57_RS01440	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FYB57_RS01455	COG1683	Conserved Protein
FYB57_RS01460	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FYB57_RS01475	COG1120	ATPase activity
FYB57_RS01480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FYB57_RS01485	COG4558	Periplasmic binding protein
FYB57_RS01490	COG3720	iron ion transport
FYB57_RS01500	COG3712	iron ion homeostasis
FYB57_RS01505	COG1595	DNA-templated transcription, initiation
FYB57_RS01525	COG1607	acyl-coa hydrolase
FYB57_RS01540	COG0437	4 iron, 4 sulfur cluster binding
FYB57_RS01545	COG2864	formate dehydrogenase
FYB57_RS01560	COG3276	selenocysteine insertion sequence binding
FYB57_RS01595	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FYB57_RS01600	COG0512	Glutamine amidotransferase of anthranilate synthase
FYB57_RS01610	COG0546	phosphoglycolate phosphatase activity
FYB57_RS01615	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FYB57_RS01620	COG2967	ApaG domain
FYB57_RS01625	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FYB57_RS01630	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FYB57_RS01635	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FYB57_RS01640	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FYB57_RS01645	COG0037	tRNA processing
FYB57_RS01665	COG1024	Enoyl-CoA hydratase
FYB57_RS01680	COG0356	it plays a direct role in the translocation of protons across the membrane
FYB57_RS01690	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FYB57_RS01695	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FYB57_RS01700	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FYB57_RS01705	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FYB57_RS01710	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FYB57_RS01715	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FYB57_RS01730	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FYB57_RS01735	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FYB57_RS01740	COG0210	DNA helicase
FYB57_RS01755	COG4608	Belongs to the ABC transporter superfamily
FYB57_RS01760	COG0444	Belongs to the ABC transporter superfamily
FYB57_RS01765	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FYB57_RS01790	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FYB57_RS01795	COG1024	Enoyl-CoA hydratase
FYB57_RS01800	COG1024	Enoyl-CoA hydratase
FYB57_RS01805	COG2070	2-Nitropropane dioxygenase
FYB57_RS01820	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYB57_RS01825	COG1250	3-hydroxyacyl-CoA dehydrogenase
FYB57_RS01845	COG2267	carboxylic ester hydrolase activity
FYB57_RS01865	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FYB57_RS01875	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FYB57_RS01875	COG2813	Specifically methylates the guanine in position
FYB57_RS01880	COG2223	nitrite transmembrane transporter activity
FYB57_RS01885	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FYB57_RS01900	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FYB57_RS01905	COG0708	Exodeoxyribonuclease III
FYB57_RS01910	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FYB57_RS01915	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FYB57_RS01920	COG0154	amidase activity
FYB57_RS01925	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FYB57_RS01930	COG1077	Cell shape determining protein MreB Mrl
FYB57_RS01935	COG1792	Involved in formation and maintenance of cell shape
FYB57_RS01945	COG0768	penicillin binding
FYB57_RS01950	COG0772	Belongs to the SEDS family
FYB57_RS01955	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FYB57_RS01960	COG0471	metal ion transport
FYB57_RS01965	COG1309	transcriptional regulator
FYB57_RS01975	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FYB57_RS01990	COG2823	Periplasmic or secreted lipoprotein
FYB57_RS01995	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FYB57_RS02000	COG0792	nuclease activity
FYB57_RS02020	COG1660	Displays ATPase and GTPase activities
FYB57_RS02035	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FYB57_RS02045	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FYB57_RS02055	COG3181	Tripartite tricarboxylate transporter family receptor
FYB57_RS02060	COG1473	amidohydrolase
FYB57_RS02065	COG1137	ATPase activity
FYB57_RS02080	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FYB57_RS02090	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FYB57_RS02110	COG1294	oxidase, subunit
FYB57_RS02120	COG4988	ABC transporter
FYB57_RS02125	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FYB57_RS02130	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FYB57_RS02145	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FYB57_RS02150	COG1238	metal cluster binding
FYB57_RS02160	COG1802	Transcriptional regulator
FYB57_RS02170	COG1984	allophanate hydrolase subunit 2
FYB57_RS02175	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FYB57_RS02185	COG0583	DNA-binding transcription factor activity
FYB57_RS02190	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FYB57_RS02195	COG5002	protein histidine kinase activity
FYB57_RS02200	COG0745	RESPONSE REGULATOR receiver
FYB57_RS02205	COG2226	methyltransferase
FYB57_RS02250	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FYB57_RS02260	COG1028	Short-chain dehydrogenase reductase Sdr
FYB57_RS02280	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FYB57_RS02285	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FYB57_RS02295	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FYB57_RS02315	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FYB57_RS02320	COG1538	Outer membrane efflux protein
FYB57_RS02330	COG0351	phosphomethylpyrimidine kinase
FYB57_RS02335	COG2022	thiamine diphosphate biosynthetic process
FYB57_RS02340	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FYB57_RS02360	COG2226	methyltransferase
FYB57_RS02370	COG1194	a g-specific adenine glycosylase
FYB57_RS02380	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FYB57_RS02385	COG2177	Part of the ABC transporter FtsEX involved in
FYB57_RS02390	COG2884	Cell division ATP-binding protein ftsE
FYB57_RS02395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYB57_RS02400	COG4597	amino acid ABC transporter
FYB57_RS02405	COG0765	amino acid transport
FYB57_RS02410	COG1126	abc transporter atp-binding protein
FYB57_RS02440	COG0477	Major facilitator Superfamily
FYB57_RS02450	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FYB57_RS02455	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FYB57_RS02470	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FYB57_RS02475	COG0237	dephospho-CoA kinase activity
FYB57_RS02480	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
FYB57_RS02490	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FYB57_RS02505	COG3539	Fimbrial protein
FYB57_RS02510	COG3539	Fimbrial protein
FYB57_RS02525	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FYB57_RS02535	COG1846	Transcriptional regulator
FYB57_RS02605	COG1028	Short-chain dehydrogenase reductase Sdr
FYB57_RS02610	COG1024	Enoyl-CoA hydratase
FYB57_RS02615	COG1960	acyl-CoA dehydrogenase activity
FYB57_RS02645	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FYB57_RS02650	COG0352	thiamine-phosphate diphosphorylase activity
FYB57_RS02655	COG0351	phosphomethylpyrimidine kinase
FYB57_RS02665	COG1678	Uncharacterized ACR, COG1678
FYB57_RS02670	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FYB57_RS02695	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FYB57_RS02705	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FYB57_RS02710	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FYB57_RS02720	COG0557	exoribonuclease II activity
FYB57_RS02730	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FYB57_RS02735	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FYB57_RS02740	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FYB57_RS02750	COG0439	Biotin carboxylase
FYB57_RS02755	COG2264	protein methyltransferase activity
FYB57_RS02765	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FYB57_RS02790	COG1696	Membrane protein involved in D-alanine export
FYB57_RS02795	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FYB57_RS02840	COG1522	sequence-specific DNA binding
FYB57_RS02855	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FYB57_RS02920	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FYB57_RS02945	COG3028	Belongs to the UPF0307 family
FYB57_RS02950	COG0312	modulator of DNA gyrase
FYB57_RS02955	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FYB57_RS02960	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FYB57_RS02965	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FYB57_RS02975	COG0316	Belongs to the HesB IscA family
FYB57_RS02985	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FYB57_RS02995	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FYB57_RS03000	COG1881	PFAM PEBP family protein
FYB57_RS03005	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FYB57_RS03010	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FYB57_RS03025	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FYB57_RS03025	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FYB57_RS03040	COG2718	Belongs to the UPF0229 family
FYB57_RS03045	COG2719	SpoVR family
FYB57_RS03105	COG0165	Argininosuccinate lyase
FYB57_RS03110	COG0589	response to stress
FYB57_RS03120	COG2816	NAD+ diphosphatase activity
FYB57_RS03125	COG4993	Dehydrogenase
FYB57_RS03150	COG3181	Tripartite tricarboxylate transporter family receptor
FYB57_RS03155	COG2979	Protein of unknown function (DUF533)
FYB57_RS03160	COG4206	TonB-dependent receptor
FYB57_RS03175	COG0741	lytic transglycosylase activity
FYB57_RS03175	COG1388	LysM domain
FYB57_RS03180	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FYB57_RS03185	COG2226	methyltransferase
FYB57_RS03190	COG0328	RNA-DNA hybrid ribonuclease activity
FYB57_RS03215	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FYB57_RS03235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYB57_RS03240	COG1129	ABC transporter
FYB57_RS03240	COG0842	Transport permease protein
FYB57_RS03245	COG0842	Transport permease protein
FYB57_RS03265	COG0463	Glycosyl transferase, family 2
FYB57_RS03270	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FYB57_RS03285	COG1073	alpha beta
FYB57_RS03295	COG0697	spore germination
FYB57_RS03300	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FYB57_RS03325	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FYB57_RS03355	COG0823	Involved in the tonB-independent uptake of proteins
FYB57_RS03365	COG0848	biopolymer transport protein
FYB57_RS03370	COG0811	peptide transport
FYB57_RS03375	COG0824	Thioesterase
FYB57_RS03380	COG0442	prolyl-tRNA aminoacylation
FYB57_RS03425	COG2084	Dehydrogenase
FYB57_RS03470	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FYB57_RS03475	COG4654	Cytochrome c, class I
FYB57_RS03480	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FYB57_RS03545	COG1473	amidohydrolase
FYB57_RS03550	COG0418	dihydroorotase activity
FYB57_RS03555	COG0488	(ABC) transporter
FYB57_RS03565	COG2001	Belongs to the MraZ family
FYB57_RS03570	COG0275	rRNA processing
FYB57_RS03575	COG3116	cell division
FYB57_RS03585	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FYB57_RS03590	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FYB57_RS03595	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FYB57_RS03605	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FYB57_RS03610	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FYB57_RS03615	COG1181	Belongs to the D-alanine--D-alanine ligase family
FYB57_RS03620	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FYB57_RS03635	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FYB57_RS03650	COG0739	heme binding
FYB57_RS03655	COG0653	protein targeting
FYB57_RS03680	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FYB57_RS03685	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FYB57_RS03695	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FYB57_RS03745	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FYB57_RS03760	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
FYB57_RS03785	COG0583	DNA-binding transcription factor activity
FYB57_RS03795	COG3181	Tripartite tricarboxylate transporter family receptor
FYB57_RS03800	COG2084	Dehydrogenase
FYB57_RS03815	COG1597	lipid kinase activity
FYB57_RS03815	COG1803	Methylglyoxal synthase
FYB57_RS03825	COG0671	phosphoesterase, PA-phosphatase related
FYB57_RS03845	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FYB57_RS03850	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FYB57_RS03855	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FYB57_RS03860	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FYB57_RS03865	COG0649	NAD binding
FYB57_RS03870	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FYB57_RS03880	COG1034	ATP synthesis coupled electron transport
FYB57_RS03885	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FYB57_RS03890	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FYB57_RS03900	COG0713	ATP synthesis coupled electron transport
FYB57_RS03915	COG1007	ATP synthesis coupled electron transport
FYB57_RS03925	COG0560	Phosphoserine phosphatase
FYB57_RS03930	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FYB57_RS03935	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FYB57_RS03940	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FYB57_RS03955	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FYB57_RS03960	COG0450	alkyl hydroperoxide reductase
FYB57_RS03980	COG1214	PFAM Peptidase M22, glycoprotease
FYB57_RS03985	COG1573	uracil-dna glycosylase
FYB57_RS03990	COG0477	Major facilitator Superfamily
FYB57_RS03995	COG1196	nuclear chromosome segregation
FYB57_RS04005	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FYB57_RS04010	COG1126	abc transporter atp-binding protein
FYB57_RS04015	COG0765	amino acid transport
FYB57_RS04020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYB57_RS04025	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FYB57_RS04030	COG2917	probably involved in intracellular septation
FYB57_RS04035	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FYB57_RS04040	COG1122	ATPase activity
FYB57_RS04045	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FYB57_RS04080	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FYB57_RS04110	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FYB57_RS04115	COG2878	Part of a membrane complex involved in electron transport
FYB57_RS04135	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FYB57_RS04140	COG0251	oxidation-reduction process
FYB57_RS04150	COG3228	Belongs to the MtfA family
FYB57_RS04155	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FYB57_RS04165	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FYB57_RS04175	COG0159	tryptophan synthase activity
FYB57_RS04180	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FYB57_RS04185	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FYB57_RS04200	COG1530	ribonuclease E activity
FYB57_RS04205	COG0564	pseudouridine synthase activity
FYB57_RS04210	COG0546	phosphoglycolate phosphatase activity
FYB57_RS04215	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FYB57_RS04220	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FYB57_RS04225	COG3023	N-Acetylmuramoyl-L-alanine amidase
FYB57_RS04235	COG0424	maF-like protein
FYB57_RS04245	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FYB57_RS04255	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FYB57_RS04265	COG1028	Short-chain dehydrogenase reductase Sdr
FYB57_RS04270	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FYB57_RS04275	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FYB57_RS04300	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FYB57_RS04335	COG0481	GTPase activity
FYB57_RS04340	COG0681	Belongs to the peptidase S26 family
FYB57_RS04345	COG0571	ribonuclease III activity
FYB57_RS04350	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FYB57_RS04355	COG1381	Involved in DNA repair and RecF pathway recombination
FYB57_RS04375	COG0670	Belongs to the BI1 family
FYB57_RS04390	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FYB57_RS04415	COG0583	DNA-binding transcription factor activity
FYB57_RS04430	COG0791	NLP P60 protein
FYB57_RS04435	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FYB57_RS04440	COG3193	protein, possibly involved in utilization of glycolate and propanediol
FYB57_RS04450	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FYB57_RS04470	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FYB57_RS04505	COG1446	asparaginase
FYB57_RS04510	COG4172	Belongs to the ABC transporter superfamily
FYB57_RS04515	COG0747	negative chemotaxis
FYB57_RS04520	COG0601	transmembrane transport
FYB57_RS04545	COG0504	CTP synthase activity
FYB57_RS04555	COG0148	phosphopyruvate hydratase activity
FYB57_RS04570	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FYB57_RS04580	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FYB57_RS04585	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FYB57_RS04625	COG1981	membrane
FYB57_RS04645	COG0039	L-malate dehydrogenase activity
FYB57_RS04650	COG2188	Transcriptional regulator
FYB57_RS04655	COG2009	succinate dehydrogenase
FYB57_RS04660	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FYB57_RS04665	COG1053	succinate dehydrogenase
FYB57_RS04670	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FYB57_RS04675	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FYB57_RS04680	COG0372	Belongs to the citrate synthase family
FYB57_RS04690	COG0583	DNA-binding transcription factor activity
FYB57_RS04695	COG3842	ATPase activity
FYB57_RS04705	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FYB57_RS04710	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FYB57_RS04720	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FYB57_RS04730	COG3128	pkhd-type hydroxylase
FYB57_RS04735	COG4774	siderophore transport
FYB57_RS04745	COG0280	phosphate acetyltransferase
FYB57_RS04745	COG0281	malic enzyme
FYB57_RS04755	COG1297	OPT oligopeptide transporter protein
FYB57_RS04760	COG0567	Dehydrogenase, E1 component
FYB57_RS04765	COG0508	dehydrogenase complex catalyzes the overall conversion of
FYB57_RS04770	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FYB57_RS04775	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FYB57_RS04780	COG1595	DNA-templated transcription, initiation
FYB57_RS04790	COG4774	siderophore transport
FYB57_RS04815	COG2183	response to ionizing radiation
FYB57_RS04820	COG1199	ATP-dependent helicase activity
FYB57_RS04830	COG0564	pseudouridine synthase activity
FYB57_RS04840	COG3243	poly(R)-hydroxyalkanoic acid synthase
FYB57_RS04845	COG1028	Short-chain dehydrogenase reductase Sdr
FYB57_RS04850	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
FYB57_RS04865	COG0672	)-iron permease
FYB57_RS04880	COG2823	Periplasmic or secreted lipoprotein
FYB57_RS04900	COG3237	CsbD-like
FYB57_RS04905	COG3038	cytochrome b561
FYB57_RS04920	COG1132	(ABC) transporter
FYB57_RS04935	COG2833	Protein of unknown function (DUF455)
FYB57_RS04940	COG2951	lytic endotransglycosylase activity
FYB57_RS04965	COG0586	Pfam SNARE associated Golgi protein
FYB57_RS05020	COG0165	Argininosuccinate lyase
FYB57_RS05040	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FYB57_RS05055	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FYB57_RS05060	COG0077	Prephenate dehydratase
FYB57_RS05060	COG1605	Chorismate mutase
FYB57_RS05065	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FYB57_RS05075	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FYB57_RS05080	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FYB57_RS05100	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FYB57_RS05105	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FYB57_RS05110	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FYB57_RS05115	COG0587	DNA-directed DNA polymerase activity
FYB57_RS05125	COG2951	lytic endotransglycosylase activity
FYB57_RS05130	COG0123	including yeast histone deacetylase and acetoin utilization protein
FYB57_RS05145	COG2985	domain, Protein
FYB57_RS05150	COG1960	acyl-CoA dehydrogenase activity
FYB57_RS05155	COG0450	alkyl hydroperoxide reductase
FYB57_RS05160	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FYB57_RS05165	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FYB57_RS05170	COG4208	sulfate ABC transporter
FYB57_RS05175	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FYB57_RS05180	COG0175	sulfate reduction
FYB57_RS05210	COG0335	large ribosomal subunit rRNA binding
FYB57_RS05225	COG3622	Belongs to the hyi family
FYB57_RS05230	COG1162	GTPase activity
FYB57_RS05235	COG0501	Belongs to the peptidase M48B family
FYB57_RS05240	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FYB57_RS05245	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FYB57_RS05250	COG3327	negative regulation of DNA-templated transcription, initiation
FYB57_RS05255	COG3396	Phenylacetate-CoA oxygenase
FYB57_RS05260	COG3460	Phenylacetate-CoA oxygenase
FYB57_RS05265	COG3396	Phenylacetate-CoA oxygenase
FYB57_RS05270	COG2151	metal-sulfur cluster biosynthetic enzyme
FYB57_RS05275	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FYB57_RS05280	COG1012	belongs to the aldehyde dehydrogenase family
FYB57_RS05285	COG1024	Enoyl-CoA hydratase
FYB57_RS05290	COG2050	protein possibly involved in aromatic compounds catabolism
FYB57_RS05320	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FYB57_RS05320	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FYB57_RS05330	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FYB57_RS05335	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FYB57_RS05340	COG2346	COG2346, Truncated hemoglobins
FYB57_RS05345	COG3642	lipopolysaccharide core region biosynthetic process
FYB57_RS05355	COG3842	ATPase activity
FYB57_RS05360	COG1176	ABC-type spermidine putrescine transport system, permease component I
FYB57_RS05365	COG1177	transmembrane transport
FYB57_RS05385	COG1322	Protein conserved in bacteria
FYB57_RS05395	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FYB57_RS05400	COG0704	Plays a role in the regulation of phosphate uptake
FYB57_RS05405	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FYB57_RS05410	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FYB57_RS05410	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FYB57_RS05415	COG1643	Atp-dependent helicase
FYB57_RS05430	COG0438	transferase activity, transferring glycosyl groups
FYB57_RS05435	COG0726	polysaccharide deacetylase
FYB57_RS05440	COG0463	Glycosyl transferase, family 2
FYB57_RS05475	COG1132	(ABC) transporter
FYB57_RS05495	COG0501	Belongs to the peptidase M48B family
FYB57_RS05540	COG1722	exodeoxyribonuclease VII activity
FYB57_RS05545	COG0142	geranyltranstransferase activity
FYB57_RS05550	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FYB57_RS05555	COG1469	GTP cyclohydrolase I activity
FYB57_RS05560	COG0360	Binds together with S18 to 16S ribosomal RNA
FYB57_RS05565	COG2965	DNA replication, synthesis of RNA primer
FYB57_RS05570	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FYB57_RS05575	COG0359	binds to the 23S rRNA
FYB57_RS05585	COG0305	Participates in initiation and elongation during chromosome replication
FYB57_RS05595	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FYB57_RS05600	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FYB57_RS05605	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FYB57_RS05610	COG3737	Protein of unknown function (DUF498/DUF598)
FYB57_RS05615	COG0436	Aminotransferase
FYB57_RS05640	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FYB57_RS05645	COG0308	aminopeptidase N
FYB57_RS05660	COG0312	modulator of DNA gyrase
FYB57_RS05665	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FYB57_RS05685	COG0277	FAD linked oxidase domain protein
FYB57_RS05690	COG0277	FAD linked oxidase domain protein
FYB57_RS05695	COG0247	lactate metabolic process
FYB57_RS05735	COG0583	DNA-binding transcription factor activity
FYB57_RS05740	COG0482	sulfurtransferase activity
FYB57_RS05745	COG0730	response to heat
FYB57_RS05750	COG0625	glutathione transferase activity
FYB57_RS05755	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FYB57_RS05760	COG3909	cytochrome
FYB57_RS05795	COG3706	GGDEF domain
FYB57_RS05810	COG2826	transposase and inactivated derivatives, IS30 family
FYB57_RS05830	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
FYB57_RS05855	COG0069	glutamate synthase activity
FYB57_RS05860	COG2391	methyltransferase activity
FYB57_RS05865	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FYB57_RS05870	COG0679	Auxin Efflux Carrier
FYB57_RS05875	COG2153	protein acetylation
FYB57_RS05895	COG0557	exoribonuclease II activity
FYB57_RS05900	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FYB57_RS05905	COG2873	o-acetylhomoserine
FYB57_RS05910	COG0776	regulation of translation
FYB57_RS05940	COG0642	Histidine kinase
FYB57_RS05945	COG3158	transport of potassium into the cell
FYB57_RS05970	COG0137	argininosuccinate synthase activity
FYB57_RS05975	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FYB57_RS05980	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FYB57_RS05990	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FYB57_RS06005	COG2186	Transcriptional regulator
FYB57_RS06035	COG3836	Belongs to the HpcH HpaI aldolase family
FYB57_RS06040	COG0268	Binds directly to 16S ribosomal RNA
FYB57_RS06085	COG0728	peptidoglycan biosynthetic process
FYB57_RS06095	COG0563	adenylate kinase activity
FYB57_RS06100	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FYB57_RS06105	COG2835	tetraacyldisaccharide 4'-kinase activity
FYB57_RS06110	COG1663	tetraacyldisaccharide 4'-kinase activity
FYB57_RS06115	COG0848	biopolymer transport protein
FYB57_RS06120	COG0811	peptide transport
FYB57_RS06125	COG1570	exodeoxyribonuclease VII activity
FYB57_RS06130	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FYB57_RS06140	COG0038	chloride channel
FYB57_RS06145	COG0183	Belongs to the thiolase family
FYB57_RS06155	COG1278	Cold shock
FYB57_RS06160	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FYB57_RS06170	COG4953	penicillin-binding protein 1C
FYB57_RS06185	COG3008	intermembrane lipid transfer
FYB57_RS06195	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FYB57_RS06195	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FYB57_RS06195	COG0506	proline dehydrogenase activity
FYB57_RS06225	COG0004	ammonium transporteR
FYB57_RS06230	COG0347	Belongs to the P(II) protein family
FYB57_RS06270	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FYB57_RS06275	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FYB57_RS06280	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FYB57_RS06285	COG0072	phenylalanine-tRNA ligase activity
FYB57_RS06285	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FYB57_RS06290	COG0776	regulation of translation
FYB57_RS06320	COG1802	Transcriptional regulator
FYB57_RS06325	COG3181	Tripartite tricarboxylate transporter family receptor
FYB57_RS06345	COG1278	Cold shock
FYB57_RS06355	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FYB57_RS06375	COG1522	sequence-specific DNA binding
FYB57_RS06425	COG5265	(ABC) transporter
FYB57_RS06445	COG0656	L-ascorbic acid biosynthetic process
FYB57_RS06450	COG0667	Aldo Keto reductase
FYB57_RS06465	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FYB57_RS06510	COG1610	YqeY-like protein
FYB57_RS06525	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FYB57_RS06530	COG3246	L-lysine catabolic process to acetate
FYB57_RS06535	COG1250	3-hydroxyacyl-CoA dehydrogenase
FYB57_RS06545	COG0318	PFAM AMP-dependent synthetase and ligase
FYB57_RS06560	COG0183	Belongs to the thiolase family
FYB57_RS06565	COG1024	Enoyl-CoA hydratase
FYB57_RS06565	COG1250	3-hydroxyacyl-CoA dehydrogenase
FYB57_RS06575	COG1024	Enoyl-CoA hydratase
FYB57_RS06575	COG1250	3-hydroxyacyl-CoA dehydrogenase
FYB57_RS06580	COG0183	Belongs to the thiolase family
FYB57_RS06595	COG1045	serine acetyltransferase
FYB57_RS06605	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FYB57_RS06610	COG0483	inositol monophosphate 1-phosphatase activity
FYB57_RS06615	COG1012	belongs to the aldehyde dehydrogenase family
FYB57_RS06620	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FYB57_RS06635	COG0210	DNA helicase
FYB57_RS06640	COG0598	Magnesium transport protein CorA
FYB57_RS06650	COG0747	negative chemotaxis
FYB57_RS06655	COG0601	transmembrane transport
FYB57_RS06660	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FYB57_RS06665	COG4172	Belongs to the ABC transporter superfamily
FYB57_RS06685	COG1346	cytolysis
FYB57_RS06695	COG1028	Short-chain dehydrogenase reductase Sdr
FYB57_RS06700	COG0783	Belongs to the Dps family
FYB57_RS06720	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
FYB57_RS06730	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FYB57_RS06735	COG1845	cytochrome c oxidase, subunit III
FYB57_RS06740	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FYB57_RS06785	COG1666	GTP binding
FYB57_RS06810	COG1028	Short-chain dehydrogenase reductase Sdr
FYB57_RS06815	COG5006	permease, DMT superfamily
FYB57_RS06840	COG2264	protein methyltransferase activity
FYB57_RS06875	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FYB57_RS06880	COG0746	molybdenum cofactor guanylyltransferase activity
FYB57_RS06885	COG0303	'Molybdopterin
FYB57_RS06890	COG0521	Mo-molybdopterin cofactor biosynthetic process
FYB57_RS06895	COG0314	molybdopterin synthase activity
FYB57_RS06905	COG0315	cyclic pyranopterin monophosphate synthase activity
FYB57_RS06910	COG0412	Dienelactone hydrolase
FYB57_RS06920	COG0678	peroxiredoxin activity
FYB57_RS06935	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FYB57_RS06945	COG0542	response to heat
FYB57_RS06960	COG1477	protein flavinylation
FYB57_RS06985	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FYB57_RS06990	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
FYB57_RS06990	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
FYB57_RS06995	COG1562	ergosterol biosynthetic process
FYB57_RS07000	COG1562	ergosterol biosynthetic process
FYB57_RS07005	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FYB57_RS07045	COG0254	rRNA binding
FYB57_RS07050	COG3483	tryptophan 2,3-dioxygenase activity
FYB57_RS07055	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FYB57_RS07060	COG2003	Belongs to the UPF0758 family
FYB57_RS07070	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FYB57_RS07075	COG0625	glutathione transferase activity
FYB57_RS07095	COG0523	cobalamin synthesis protein
FYB57_RS07105	COG0583	DNA-binding transcription factor activity
FYB57_RS07115	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FYB57_RS07120	COG1187	pseudouridine synthase activity
FYB57_RS07125	COG0779	Required for maturation of 30S ribosomal subunits
FYB57_RS07130	COG2251	uridine kinase activity
FYB57_RS07130	COG0195	Participates in both transcription termination and antitermination
FYB57_RS07135	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FYB57_RS07140	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FYB57_RS07145	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FYB57_RS07150	COG1217	gtp-binding protein TYPA
FYB57_RS07165	COG1802	Transcriptional regulator
FYB57_RS07175	COG1024	Enoyl-CoA hydratase
FYB57_RS07180	COG0318	PFAM AMP-dependent synthetase and ligase
FYB57_RS07190	COG2032	superoxide dismutase activity
FYB57_RS07205	COG4120	Belongs to the binding-protein-dependent transport system permease family
FYB57_RS07210	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FYB57_RS07215	COG0725	ABC transporter, periplasmic molybdate-binding protein
FYB57_RS07220	COG4149	molybdate abc transporter
FYB57_RS07250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYB57_RS07255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYB57_RS07260	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FYB57_RS07270	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FYB57_RS07275	COG0736	holo-[acyl-carrier-protein] synthase activity
FYB57_RS07280	COG1472	Belongs to the glycosyl hydrolase 3 family
FYB57_RS07285	COG0322	excinuclease ABC activity
FYB57_RS07290	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FYB57_RS07300	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FYB57_RS07300	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FYB57_RS07305	COG2224	Isocitrate lyase
FYB57_RS07310	COG1846	Transcriptional regulator
FYB57_RS07315	COG1764	response to oxidative stress
FYB57_RS07320	COG1131	(ABC) transporter
FYB57_RS07330	COG0628	permease
FYB57_RS07355	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
FYB57_RS07365	COG2814	Major facilitator Superfamily
FYB57_RS07385	COG3015	lipoprotein NlpE involved in copper resistance
FYB57_RS07395	COG3530	Putative quorum-sensing-regulated virulence factor
FYB57_RS07410	COG0494	nUDIX hydrolase
FYB57_RS07420	COG0697	spore germination
FYB57_RS07425	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FYB57_RS07450	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FYB57_RS07455	COG1702	phosphate starvation-inducible protein PhoH
FYB57_RS07460	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FYB57_RS07465	COG4535	Mg2 and Co2 transporter CorC
FYB57_RS07470	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FYB57_RS07475	COG0667	Aldo Keto reductase
FYB57_RS07495	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FYB57_RS07500	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FYB57_RS07505	COG1862	Preprotein translocase
FYB57_RS07510	COG0343	queuine tRNA-ribosyltransferase activity
FYB57_RS07515	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FYB57_RS07520	COG2027	D-alanyl-D-alanine carboxypeptidase
FYB57_RS07525	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FYB57_RS07530	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FYB57_RS07530	COG1648	precorrin-2 dehydrogenase activity
FYB57_RS07540	COG4575	ribosome binding
FYB57_RS07565	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FYB57_RS07570	COG0741	lytic transglycosylase activity
FYB57_RS07575	COG0436	Aminotransferase
FYB57_RS07585	COG0281	malic enzyme
FYB57_RS07585	COG0280	phosphate acetyltransferase
FYB57_RS07600	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FYB57_RS07605	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FYB57_RS07610	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FYB57_RS07615	COG0126	phosphoglycerate kinase activity
FYB57_RS07630	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FYB57_RS07645	COG0625	glutathione transferase activity
FYB57_RS07665	COG0789	Transcriptional regulator
FYB57_RS07680	COG0306	phosphate transporter
FYB57_RS07685	COG0521	Mo-molybdopterin cofactor biosynthetic process
FYB57_RS07695	COG0739	heme binding
FYB57_RS07705	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FYB57_RS07745	COG0456	acetyltransferase
FYB57_RS07750	COG1301	dicarboxylic acid transport
FYB57_RS07760	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FYB57_RS07765	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FYB57_RS07770	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FYB57_RS07775	COG0009	L-threonylcarbamoyladenylate synthase
FYB57_RS07785	COG4771	TonB-dependent receptor
FYB57_RS07815	COG1960	acyl-CoA dehydrogenase activity
FYB57_RS07820	COG0028	Belongs to the TPP enzyme family
FYB57_RS07825	COG0583	DNA-binding transcription factor activity
FYB57_RS07830	COG4974	Belongs to the 'phage' integrase family
FYB57_RS07835	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FYB57_RS07840	COG1686	Belongs to the peptidase S11 family
FYB57_RS07870	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FYB57_RS07875	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FYB57_RS07880	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FYB57_RS07900	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FYB57_RS07905	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FYB57_RS07910	COG0505	Belongs to the CarA family
FYB57_RS07915	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FYB57_RS07925	COG1028	Short-chain dehydrogenase reductase Sdr
FYB57_RS07930	COG0406	alpha-ribazole phosphatase activity
FYB57_RS07960	COG2233	PERMEase
FYB57_RS07965	COG3620	sequence-specific DNA binding
FYB57_RS07975	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FYB57_RS07985	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FYB57_RS07990	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FYB57_RS08000	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FYB57_RS08015	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FYB57_RS08035	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FYB57_RS08095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FYB57_RS08125	COG0540	Belongs to the ATCase OTCase family
FYB57_RS08130	COG2974	May be involved in recombination
FYB57_RS08155	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FYB57_RS08160	COG2137	regulation of response to DNA damage stimulus
FYB57_RS08170	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FYB57_RS08190	COG0045	succinate-CoA ligase (ADP-forming) activity
FYB57_RS08195	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FYB57_RS08200	COG0861	Integral membrane protein TerC family
FYB57_RS08205	COG0861	Integral membrane protein TerC family
FYB57_RS08210	COG0181	hydroxymethylbilane synthase activity
FYB57_RS08250	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FYB57_RS08300	COG1450	Type ii and iii secretion system protein
FYB57_RS08350	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FYB57_RS08360	COG1295	ribonuclease BN
FYB57_RS08370	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FYB57_RS08390	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FYB57_RS08395	COG0501	Belongs to the peptidase M48B family
FYB57_RS08400	COG2197	response regulator
FYB57_RS08425	COG0066	3-isopropylmalate dehydratase activity
FYB57_RS08435	COG0473	3-isopropylmalate dehydrogenase activity
FYB57_RS08440	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FYB57_RS08450	COG0101	tRNA pseudouridine synthase activity
FYB57_RS08455	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FYB57_RS08460	COG0135	phosphoribosylanthranilate isomerase activity
FYB57_RS08480	COG2801	Transposase and inactivated derivatives
FYB57_RS08485	COG2801	Transposase and inactivated derivatives
FYB57_RS08525	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FYB57_RS08530	COG2197	response regulator
FYB57_RS08535	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FYB57_RS08540	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FYB57_RS08555	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FYB57_RS08560	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FYB57_RS08570	COG1764	response to oxidative stress
FYB57_RS08585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYB57_RS08590	COG0765	amino acid transport
FYB57_RS08595	COG0765	amino acid transport
FYB57_RS08605	COG0756	dUTP diphosphatase activity
FYB57_RS08635	COG1522	sequence-specific DNA binding
FYB57_RS08655	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FYB57_RS08660	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FYB57_RS08665	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FYB57_RS08670	COG0196	riboflavin kinase activity
FYB57_RS08680	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FYB57_RS08680	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FYB57_RS08710	COG0210	DNA helicase
FYB57_RS08715	COG4771	TonB-dependent receptor
FYB57_RS08720	COG0488	(ABC) transporter
FYB57_RS08725	COG2890	protein-(glutamine-N5) methyltransferase activity
FYB57_RS08730	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FYB57_RS08735	COG2171	N-acyltransferase activity
FYB57_RS08790	COG2801	Transposase and inactivated derivatives
FYB57_RS08830	COG2814	Major facilitator Superfamily
FYB57_RS08855	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FYB57_RS08860	COG2900	Belongs to the SlyX family
FYB57_RS08875	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FYB57_RS08895	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FYB57_RS08920	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FYB57_RS08925	COG0583	DNA-binding transcription factor activity
FYB57_RS08930	COG1028	Short-chain dehydrogenase reductase Sdr
FYB57_RS08940	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FYB57_RS08945	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FYB57_RS08960	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FYB57_RS08965	COG0508	dehydrogenase complex catalyzes the overall conversion of
FYB57_RS08970	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FYB57_RS08985	COG4566	intracellular signal transduction
FYB57_RS08990	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FYB57_RS09010	COG1999	signal sequence binding
FYB57_RS09030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYB57_RS09035	COG0583	DNA-binding transcription factor activity
FYB57_RS09040	COG1187	pseudouridine synthase activity
FYB57_RS09045	COG3161	chorismate lyase activity
FYB57_RS09060	COG1280	lysine exporter protein (LysE YggA)
FYB57_RS09100	COG1129	ABC transporter
FYB57_RS09115	COG0583	DNA-binding transcription factor activity
FYB57_RS09145	COG1185	polyribonucleotide nucleotidyltransferase activity
FYB57_RS09150	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FYB57_RS09165	COG1183	phosphatidylcholine synthase activity
FYB57_RS09175	COG0440	acetolactate synthase activity
FYB57_RS09180	COG0028	Belongs to the TPP enzyme family
FYB57_RS09205	COG3022	response to hydroperoxide
FYB57_RS09215	COG1028	Short-chain dehydrogenase reductase Sdr
FYB57_RS09230	COG3486	L-lysine 6-monooxygenase (NADPH) activity
FYB57_RS09260	COG2814	Major facilitator Superfamily
FYB57_RS09290	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FYB57_RS09325	COG2733	membrane
FYB57_RS09350	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FYB57_RS09370	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYB57_RS09375	COG1129	ABC transporter
FYB57_RS09375	COG0842	Transport permease protein
FYB57_RS09380	COG0842	Transport permease protein
FYB57_RS09390	COG1028	Short-chain dehydrogenase reductase Sdr
FYB57_RS09400	COG2259	Doxx family
FYB57_RS09430	COG0415	Belongs to the DNA photolyase family
FYB57_RS09450	COG0386	Belongs to the glutathione peroxidase family
FYB57_RS09465	COG0095	Lipoate-protein ligase
FYB57_RS09475	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FYB57_RS09485	COG0010	Belongs to the arginase family
FYB57_RS09495	COG0765	amino acid transport
FYB57_RS09500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYB57_RS09515	COG0084	hydrolase, TatD family'
FYB57_RS09525	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FYB57_RS09530	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FYB57_RS09540	COG2175	clavaminate synthase activity
FYB57_RS09545	COG0583	DNA-binding transcription factor activity
FYB57_RS09570	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FYB57_RS09580	COG2914	Belongs to the UPF0125 (RnfH) family
FYB57_RS09590	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FYB57_RS09625	COG0519	Catalyzes the synthesis of GMP from XMP
FYB57_RS09625	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FYB57_RS09635	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FYB57_RS09645	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FYB57_RS09650	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FYB57_RS09655	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FYB57_RS09665	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FYB57_RS09670	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FYB57_RS09680	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FYB57_RS09685	COG0750	zinc metalloprotease
FYB57_RS09690	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FYB57_RS09700	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FYB57_RS09705	COG0233	cytoplasmic translational termination
FYB57_RS09710	COG0528	UMP kinase activity
FYB57_RS09715	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FYB57_RS09720	COG0052	Belongs to the universal ribosomal protein uS2 family
FYB57_RS09725	COG0024	Methionine aminopeptidase
FYB57_RS09730	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FYB57_RS09750	COG1286	toxin biosynthetic process
FYB57_RS09760	COG0285	dihydrofolate synthase activity
FYB57_RS09770	COG3181	Tripartite tricarboxylate transporter family receptor
FYB57_RS09775	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYB57_RS09815	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FYB57_RS09825	COG1677	Flagellar hook-basal body complex protein FliE
FYB57_RS09835	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FYB57_RS09840	COG1317	bacterial-type flagellum organization
FYB57_RS09860	COG1580	Controls the rotational direction of flagella during chemotaxis
FYB57_RS09870	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FYB57_RS09895	COG0840	transmembrane signaling receptor activity
FYB57_RS09900	COG0840	transmembrane signaling receptor activity
FYB57_RS09920	COG1191	sigma factor activity
FYB57_RS09955	COG2199	diguanylate cyclase activity
FYB57_RS09955	COG2203	Gaf domain
FYB57_RS09965	COG1619	proteins homologs of microcin C7 resistance protein MccF
FYB57_RS09990	COG1126	abc transporter atp-binding protein
FYB57_RS09995	COG0765	amino acid transport
FYB57_RS10000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYB57_RS10045	COG2200	EAL domain
FYB57_RS10065	COG1253	flavin adenine dinucleotide binding
FYB57_RS10070	COG3706	GGDEF domain
FYB57_RS10070	COG4251	negative regulation of phosphorylation
FYB57_RS10070	COG5001	Diguanylate cyclase
FYB57_RS10070	COG2203	Gaf domain
FYB57_RS10075	COG2197	response regulator
FYB57_RS10080	COG2205	protein histidine kinase activity
FYB57_RS10080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYB57_RS10105	COG0076	glutamate decarboxylase activity
FYB57_RS10110	COG2985	domain, Protein
FYB57_RS10115	COG3189	MarR family transcriptional regulator
FYB57_RS10125	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FYB57_RS10135	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FYB57_RS10135	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FYB57_RS10145	COG0028	Belongs to the TPP enzyme family
FYB57_RS10155	COG1012	belongs to the aldehyde dehydrogenase family
FYB57_RS10165	COG0688	phosphatidylethanolamine metabolic process
FYB57_RS10170	COG1304	FMN binding
FYB57_RS10175	COG1464	Belongs to the NlpA lipoprotein family
FYB57_RS10195	COG0697	spore germination
FYB57_RS10200	COG2133	pyrroloquinoline quinone binding
FYB57_RS10205	COG0625	glutathione transferase activity
FYB57_RS10215	COG1794	racemase activity, acting on amino acids and derivatives
FYB57_RS10235	COG0559	Belongs to the binding-protein-dependent transport system permease family
FYB57_RS10245	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FYB57_RS10260	COG1175	transmembrane transport
FYB57_RS10265	COG0395	ABC-type sugar transport system, permease component
FYB57_RS10270	COG3842	ATPase activity
FYB57_RS10295	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FYB57_RS10310	COG0438	transferase activity, transferring glycosyl groups
FYB57_RS10335	COG0463	Glycosyl transferase, family 2
FYB57_RS10350	COG0783	Belongs to the Dps family
FYB57_RS10355	COG0583	DNA-binding transcription factor activity
FYB57_RS10360	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FYB57_RS10390	COG1840	ABC-type Fe3 transport system, periplasmic component
FYB57_RS10400	COG3842	ATPase activity
FYB57_RS10405	COG1741	Belongs to the pirin family
FYB57_RS10410	COG1741	Belongs to the pirin family
FYB57_RS10415	COG0583	DNA-binding transcription factor activity
FYB57_RS10430	COG0174	glutamine synthetase
FYB57_RS10435	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FYB57_RS10440	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FYB57_RS10450	COG0840	transmembrane signaling receptor activity
FYB57_RS10460	COG0583	DNA-binding transcription factor activity
FYB57_RS10465	COG1960	acyl-CoA dehydrogenase activity
FYB57_RS10470	COG2079	MmgE PrpD family protein
FYB57_RS10480	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FYB57_RS10485	COG1561	YicC-like family, N-terminal region
FYB57_RS10495	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FYB57_RS10500	COG0791	NLP P60 protein
FYB57_RS10505	COG1028	Short-chain dehydrogenase reductase Sdr
FYB57_RS10510	COG0194	GDP metabolic process
FYB57_RS10515	COG1758	RNA polymerase activity
FYB57_RS10520	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FYB57_RS10525	COG1126	abc transporter atp-binding protein
FYB57_RS10530	COG0765	amino acid transport
FYB57_RS10535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYB57_RS10545	COG2831	hemolysin activation secretion protein
FYB57_RS10555	COG3188	usher protein
FYB57_RS10560	COG3121	Chaperone
FYB57_RS10575	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
FYB57_RS10575	COG3210	domain, Protein
FYB57_RS10575	COG3064	Membrane
FYB57_RS10585	COG4181	ATPase activity
FYB57_RS10595	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FYB57_RS10600	COG0584	glycerophosphoryl diester phosphodiesterase
FYB57_RS10605	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FYB57_RS10615	COG0678	peroxiredoxin activity
FYB57_RS10615	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FYB57_RS10625	COG2217	Heavy metal translocating P-type atpase
FYB57_RS10630	COG0789	Transcriptional regulator
FYB57_RS10635	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FYB57_RS10670	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FYB57_RS10680	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FYB57_RS10705	COG0583	DNA-binding transcription factor activity
FYB57_RS10710	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FYB57_RS10715	COG2252	PERMEase
FYB57_RS10720	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FYB57_RS10725	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FYB57_RS10760	COG0488	(ABC) transporter
FYB57_RS10765	COG1619	proteins homologs of microcin C7 resistance protein MccF
FYB57_RS10770	COG0590	tRNA wobble adenosine to inosine editing
FYB57_RS10785	COG1320	monovalent cation:proton antiporter activity
FYB57_RS10790	COG2212	antiporter activity
FYB57_RS10795	COG1863	multisubunit Na H antiporter MnhE subunit
FYB57_RS10800	COG0651	ATP synthesis coupled electron transport
FYB57_RS10805	COG1006	Multisubunit Na H antiporter MnhC subunit
FYB57_RS10810	COG2111	Na H antiporter
FYB57_RS10810	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FYB57_RS10815	COG3181	Tripartite tricarboxylate transporter family receptor
FYB57_RS10840	COG0420	3'-5' exonuclease activity
FYB57_RS10875	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FYB57_RS10885	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FYB57_RS10895	COG2130	NADP-dependent
FYB57_RS10900	COG1309	transcriptional regulator
FYB57_RS10910	COG1131	(ABC) transporter
FYB57_RS10915	COG0842	Transport permease protein
FYB57_RS10925	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FYB57_RS10960	COG0602	queuosine metabolic process
FYB57_RS10965	COG0720	synthase
FYB57_RS11000	COG0587	DNA-directed DNA polymerase activity
FYB57_RS11010	COG0390	transport system, permease component
FYB57_RS11015	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FYB57_RS11020	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
FYB57_RS11075	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FYB57_RS11100	COG5507	3-demethylubiquinone-9 3-methyltransferase
FYB57_RS11135	COG1396	sequence-specific DNA binding
FYB57_RS11160	COG0583	DNA-binding transcription factor activity
FYB57_RS11165	COG2814	Major facilitator Superfamily
FYB57_RS11190	COG2807	transmembrane transport
FYB57_RS11195	COG2207	Transcriptional regulator
FYB57_RS11200	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FYB57_RS11205	COG2814	Major facilitator Superfamily
FYB57_RS11220	COG1012	belongs to the aldehyde dehydrogenase family
FYB57_RS11255	COG0583	DNA-binding transcription factor activity
FYB57_RS11280	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FYB57_RS11305	COG0384	phenazine biosynthesis protein PhzF
FYB57_RS11310	COG1733	regulation of RNA biosynthetic process
FYB57_RS11345	COG3177	Filamentation induced by cAMP protein fic
FYB57_RS11355	COG0519	Catalyzes the synthesis of GMP from XMP
FYB57_RS11355	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FYB57_RS11370	COG1695	Transcriptional regulator
FYB57_RS11385	COG2072	flavoprotein involved in K transport
FYB57_RS11390	COG0601	transmembrane transport
FYB57_RS11410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FYB57_RS11420	COG4608	Belongs to the ABC transporter superfamily
FYB57_RS11425	COG0747	negative chemotaxis
FYB57_RS11465	COG0047	phosphoribosylformylglycinamidine synthase activity
FYB57_RS11465	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FYB57_RS11470	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FYB57_RS11490	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FYB57_RS11490	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FYB57_RS11495	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FYB57_RS11505	COG0613	PHP domain protein
FYB57_RS11565	COG1012	belongs to the aldehyde dehydrogenase family
FYB57_RS11575	COG0583	DNA-binding transcription factor activity
FYB57_RS11595	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FYB57_RS11605	COG3181	Tripartite tricarboxylate transporter family receptor
FYB57_RS11615	COG3181	Tripartite tricarboxylate transporter family receptor
FYB57_RS11645	COG1595	DNA-templated transcription, initiation
FYB57_RS11650	COG3712	iron ion homeostasis
FYB57_RS11660	COG0084	hydrolase, TatD family'
FYB57_RS11665	COG1136	(ABC) transporter
FYB57_RS11680	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FYB57_RS11690	COG1028	Short-chain dehydrogenase reductase Sdr
FYB57_RS11695	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FYB57_RS11705	COG1803	Methylglyoxal synthase
FYB57_RS11725	COG2801	Transposase and inactivated derivatives
FYB57_RS11730	COG2801	Transposase and inactivated derivatives
FYB57_RS11755	COG2975	iron-sulfur cluster assembly
FYB57_RS11760	COG0633	Ferredoxin
FYB57_RS11765	COG0443	Heat shock 70 kDa protein
FYB57_RS11770	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FYB57_RS11775	COG0316	Belongs to the HesB IscA family
FYB57_RS11780	COG0822	iron-sulfur transferase activity
FYB57_RS11785	COG1104	cysteine desulfurase activity
FYB57_RS11795	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FYB57_RS11800	COG0556	nucleotide-excision repair
FYB57_RS11815	COG0583	DNA-binding transcription factor activity
FYB57_RS11835	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FYB57_RS11875	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FYB57_RS11890	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FYB57_RS11900	COG0740	serine-type endopeptidase activity
FYB57_RS11905	COG0544	peptidyl-prolyl cis-trans isomerase activity
FYB57_RS11950	COG2801	Transposase and inactivated derivatives
FYB57_RS11960	COG1278	Cold shock
FYB57_RS11990	COG2433	Pfam Transposase IS66
FYB57_RS12045	COG2963	transposase activity
FYB57_RS12055	COG1530	ribonuclease E activity
FYB57_RS12090	COG1846	Transcriptional regulator
FYB57_RS12100	COG1566	PFAM secretion protein HlyD family protein
FYB57_RS12105	COG2814	Major facilitator Superfamily
FYB57_RS12130	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FYB57_RS12135	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FYB57_RS12145	COG0433	COG0433 Predicted ATPase
FYB57_RS12150	COG0217	transcriptional regulatory protein
FYB57_RS12155	COG0151	Belongs to the GarS family
FYB57_RS12165	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FYB57_RS12170	COG0799	negative regulation of ribosome biogenesis
FYB57_RS12175	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FYB57_RS12180	COG0424	maF-like protein
FYB57_RS12190	COG4191	Histidine kinase
FYB57_RS12195	COG2204	response regulator
FYB57_RS12220	COG0500	methyltransferase
FYB57_RS12235	COG0803	Belongs to the bacterial solute-binding protein 9 family
FYB57_RS12240	COG1121	(ABC) transporter
FYB57_RS12245	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FYB57_RS12250	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FYB57_RS12265	COG4993	Dehydrogenase
FYB57_RS12275	COG4772	TonB-dependent receptor
FYB57_RS12280	COG2814	Major facilitator Superfamily
FYB57_RS12300	COG0037	tRNA processing
FYB57_RS12305	COG0825	malonyl-CoA metabolic process
FYB57_RS12315	COG0215	cysteine-tRNA ligase activity
FYB57_RS12325	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FYB57_RS12330	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FYB57_RS12335	COG1968	undecaprenyl-diphosphatase activity
FYB57_RS12340	COG1253	flavin adenine dinucleotide binding
FYB57_RS12345	COG0483	inositol monophosphate 1-phosphatase activity
FYB57_RS12365	COG0668	transmembrane transport
FYB57_RS12390	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FYB57_RS12400	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FYB57_RS12415	COG1802	Transcriptional regulator
FYB57_RS12435	COG3360	Dodecin
FYB57_RS12455	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FYB57_RS12460	COG2850	peptidyl-arginine hydroxylation
FYB57_RS12470	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
FYB57_RS12475	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FYB57_RS12480	COG1994	Peptidase M50
FYB57_RS12485	COG0009	L-threonylcarbamoyladenylate synthase
FYB57_RS12490	COG2321	neutral zinc metallopeptidase
FYB57_RS12510	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FYB57_RS12520	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FYB57_RS12530	COG2271	Major facilitator Superfamily
FYB57_RS12605	COG2202	Pas domain
FYB57_RS12605	COG2200	EAL domain
FYB57_RS12605	COG2199	diguanylate cyclase activity
FYB57_RS12610	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
FYB57_RS12630	COG1960	acyl-CoA dehydrogenase activity
FYB57_RS12635	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYB57_RS12640	COG2186	Transcriptional regulator
FYB57_RS12665	COG1595	DNA-templated transcription, initiation
FYB57_RS12700	COG1028	Short-chain dehydrogenase reductase Sdr
FYB57_RS12715	COG0179	Fumarylacetoacetate (FAA) hydrolase
FYB57_RS12735	COG4604	ABC transporter, ATP-binding protein
FYB57_RS12740	COG4605	iron ion homeostasis
FYB57_RS12745	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FYB57_RS12750	COG4607	ABC-type enterochelin transport system periplasmic component
FYB57_RS12755	COG0438	transferase activity, transferring glycosyl groups
FYB57_RS12765	COG0149	triose-phosphate isomerase activity
FYB57_RS12770	COG3321	synthase
FYB57_RS12770	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FYB57_RS12770	COG0604	alcohol dehydrogenase
FYB57_RS12770	COG4221	oxidoreductase activity
FYB57_RS12800	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FYB57_RS12800	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FYB57_RS12805	COG0668	transmembrane transport
FYB57_RS12810	COG0165	Argininosuccinate lyase
FYB57_RS12820	COG0789	Transcriptional regulator
FYB57_RS12830	COG0501	Belongs to the peptidase M48B family
FYB57_RS12835	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FYB57_RS12860	COG1024	Enoyl-CoA hydratase
FYB57_RS12865	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYB57_RS12885	COG3468	outer membrane autotransporter barrel domain protein
FYB57_RS12930	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FYB57_RS12935	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FYB57_RS12940	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FYB57_RS12945	COG1674	ftsk spoiiie
FYB57_RS12950	COG0492	ferredoxin-NADP+ reductase activity
FYB57_RS12955	COG1193	negative regulation of DNA recombination
FYB57_RS12970	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FYB57_RS12985	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FYB57_RS12990	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FYB57_RS12995	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FYB57_RS13005	COG0745	RESPONSE REGULATOR receiver
FYB57_RS13040	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FYB57_RS13060	COG0612	Peptidase, M16
FYB57_RS13070	COG0443	Heat shock 70 kDa protein
FYB57_RS13080	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FYB57_RS13090	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FYB57_RS13095	COG1420	regulation of RNA biosynthetic process
FYB57_RS13100	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FYB57_RS13105	COG0497	DNA recombination
FYB57_RS13135	COG0735	belongs to the Fur family
FYB57_RS13140	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FYB57_RS13185	COG2828	Protein conserved in bacteria
FYB57_RS13190	COG1280	lysine exporter protein (LysE YggA)
FYB57_RS13195	COG3181	Tripartite tricarboxylate transporter family receptor
FYB57_RS13210	COG1028	Short-chain dehydrogenase reductase Sdr
FYB57_RS13220	COG1802	Transcriptional regulator
FYB57_RS13225	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FYB57_RS13230	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FYB57_RS13235	COG1335	isochorismatase
FYB57_RS13240	COG0523	cobalamin synthesis protein
FYB57_RS13270	COG0583	DNA-binding transcription factor activity
FYB57_RS13280	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FYB57_RS13285	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FYB57_RS13290	COG0167	dihydroorotate dehydrogenase activity
FYB57_RS13335	COG1414	Transcriptional regulator
FYB57_RS13355	COG0513	Belongs to the DEAD box helicase family
FYB57_RS13380	COG0429	hydrolase of the alpha beta-hydrolase fold
FYB57_RS13425	COG0006	proline dipeptidase activity
FYB57_RS13435	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FYB57_RS13465	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FYB57_RS13470	COG0632	four-way junction helicase activity
FYB57_RS13485	COG2255	four-way junction helicase activity
FYB57_RS13490	COG0514	ATP-dependent DNA helicase (RecQ)
FYB57_RS13510	COG1294	oxidase, subunit
FYB57_RS13520	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FYB57_RS13525	COG0850	regulation of cytokinetic process
FYB57_RS13530	COG2894	cell division
FYB57_RS13535	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FYB57_RS13560	COG0488	(ABC) transporter
FYB57_RS13575	COG4608	Belongs to the ABC transporter superfamily
FYB57_RS13580	COG0444	Belongs to the ABC transporter superfamily
FYB57_RS13585	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FYB57_RS13600	COG1215	transferase activity, transferring glycosyl groups
FYB57_RS13605	COG0583	DNA-binding transcription factor activity
FYB57_RS13610	COG1368	sulfuric ester hydrolase activity
FYB57_RS13615	COG1686	Belongs to the peptidase S11 family
FYB57_RS13625	COG1280	lysine exporter protein (LysE YggA)
FYB57_RS13635	COG1064	alcohol dehydrogenase
FYB57_RS13640	COG4191	Histidine kinase
FYB57_RS13645	COG4566	intracellular signal transduction
FYB57_RS13655	COG1802	Transcriptional regulator
FYB57_RS13680	COG3181	Tripartite tricarboxylate transporter family receptor
FYB57_RS13685	COG0513	Belongs to the DEAD box helicase family
FYB57_RS13690	COG0668	transmembrane transport
FYB57_RS13705	COG1595	DNA-templated transcription, initiation
FYB57_RS13745	COG0583	DNA-binding transcription factor activity
FYB57_RS13750	COG0531	amino acid
FYB57_RS13755	COG1982	Orn Lys Arg decarboxylase major
FYB57_RS13780	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FYB57_RS13785	COG0459	protein refolding
FYB57_RS13795	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FYB57_RS13800	COG1252	NADH dehydrogenase
FYB57_RS13805	COG0284	orotidine-5'-phosphate decarboxylase activity
FYB57_RS13815	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FYB57_RS13825	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FYB57_RS13830	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FYB57_RS13860	COG1595	DNA-templated transcription, initiation
FYB57_RS13870	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FYB57_RS13875	COG3639	organic phosphonate transmembrane transporter activity
FYB57_RS13880	COG3639	organic phosphonate transmembrane transporter activity
FYB57_RS13895	COG0742	ribosomal rna small subunit methyltransferase
FYB57_RS13900	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FYB57_RS13905	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FYB57_RS13910	COG3135	benzoate transporter
FYB57_RS13930	COG4774	siderophore transport
FYB57_RS13955	COG1024	Enoyl-CoA hydratase
FYB57_RS13960	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FYB57_RS13965	COG1960	acyl-CoA dehydrogenase activity
FYB57_RS13975	COG0318	PFAM AMP-dependent synthetase and ligase
FYB57_RS13980	COG3181	Tripartite tricarboxylate transporter family receptor
FYB57_RS13990	COG0583	DNA-binding transcription factor activity
FYB57_RS14015	COG0277	FAD linked oxidase domain protein
FYB57_RS14035	COG1802	Transcriptional regulator
FYB57_RS14050	COG2271	Major facilitator Superfamily
FYB57_RS14060	COG0583	DNA-binding transcription factor activity
FYB57_RS14085	COG0012	GTP binding
FYB57_RS14095	COG0193	aminoacyl-tRNA hydrolase activity
FYB57_RS14100	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FYB57_RS14105	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FYB57_RS14115	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FYB57_RS14130	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FYB57_RS14155	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FYB57_RS14165	COG1368	sulfuric ester hydrolase activity
FYB57_RS14170	COG2186	Transcriptional regulator
FYB57_RS14180	COG3181	Tripartite tricarboxylate transporter family receptor
FYB57_RS14195	COG0277	FAD linked oxidase domain protein
FYB57_RS14210	COG0166	Belongs to the GPI family
FYB57_RS14215	COG0438	transferase activity, transferring glycosyl groups
FYB57_RS14220	COG0438	transferase activity, transferring glycosyl groups
FYB57_RS14235	COG0438	transferase activity, transferring glycosyl groups
FYB57_RS14250	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FYB57_RS14255	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FYB57_RS14270	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
FYB57_RS14280	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FYB57_RS14290	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FYB57_RS14295	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FYB57_RS14310	COG0747	negative chemotaxis
FYB57_RS14320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FYB57_RS14325	COG4172	Belongs to the ABC transporter superfamily
FYB57_RS14350	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FYB57_RS14350	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FYB57_RS14355	COG0509	glycine decarboxylation via glycine cleavage system
FYB57_RS14360	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FYB57_RS14365	COG2081	HI0933 family
FYB57_RS14380	COG0456	acetyltransferase
FYB57_RS14385	COG0717	Belongs to the dCTP deaminase family
FYB57_RS14400	COG0489	protein tyrosine kinase activity
FYB57_RS14410	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FYB57_RS14410	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FYB57_RS14435	COG3539	Fimbrial protein
FYB57_RS14450	COG0745	RESPONSE REGULATOR receiver
FYB57_RS14480	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
FYB57_RS14495	COG2084	Dehydrogenase
FYB57_RS14500	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FYB57_RS14525	COG3842	ATPase activity
FYB57_RS14530	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FYB57_RS14535	COG1960	acyl-CoA dehydrogenase activity
FYB57_RS14545	COG0583	DNA-binding transcription factor activity
FYB57_RS14555	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYB57_RS14560	COG1024	Enoyl-CoA hydratase
FYB57_RS14580	COG0583	DNA-binding transcription factor activity
FYB57_RS14585	COG1408	metallophosphoesterase
FYB57_RS14590	COG0625	glutathione transferase activity
FYB57_RS14625	COG0426	domain, Protein
FYB57_RS14625	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FYB57_RS14630	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FYB57_RS14635	COG0583	DNA-binding transcription factor activity
FYB57_RS14645	COG1024	Enoyl-CoA hydratase
FYB57_RS14655	COG1960	acyl-CoA dehydrogenase activity
FYB57_RS14660	COG1028	Short-chain dehydrogenase reductase Sdr
FYB57_RS14665	COG1028	Short-chain dehydrogenase reductase Sdr
FYB57_RS14685	COG3181	Tripartite tricarboxylate transporter family receptor
FYB57_RS14690	COG1028	Short-chain dehydrogenase reductase Sdr
FYB57_RS14700	COG3181	Tripartite tricarboxylate transporter family receptor
FYB57_RS14740	COG0583	DNA-binding transcription factor activity
FYB57_RS14745	COG1960	acyl-CoA dehydrogenase activity
FYB57_RS14750	COG3181	Tripartite tricarboxylate transporter family receptor
FYB57_RS14755	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYB57_RS14760	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FYB57_RS14785	COG0560	Phosphoserine phosphatase
FYB57_RS14790	COG0583	DNA-binding transcription factor activity
FYB57_RS14800	COG3842	ATPase activity
FYB57_RS14815	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FYB57_RS14835	COG0625	glutathione transferase activity
FYB57_RS14875	COG4336	lyase activity
FYB57_RS14885	COG0326	Molecular chaperone. Has ATPase activity
FYB57_RS14890	COG2233	PERMEase
FYB57_RS14930	COG2818	Glycosylase
FYB57_RS14935	COG0727	PFAM Uncharacterised protein family (UPF0153)
FYB57_RS14960	COG0402	S-adenosylhomocysteine deaminase activity
FYB57_RS14975	COG0156	8-amino-7-oxononanoate synthase activity
FYB57_RS14980	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FYB57_RS15030	COG1464	Belongs to the NlpA lipoprotein family
FYB57_RS15035	COG2011	ABC-type metal ion transport system permease component
FYB57_RS15040	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FYB57_RS15045	COG1501	Belongs to the glycosyl hydrolase 31 family
FYB57_RS15050	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FYB57_RS15050	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FYB57_RS15055	COG0483	inositol monophosphate 1-phosphatase activity
FYB57_RS15060	COG0318	PFAM AMP-dependent synthetase and ligase
FYB57_RS15065	COG1473	amidohydrolase
FYB57_RS15070	COG0583	DNA-binding transcription factor activity
FYB57_RS15075	COG2855	membrane
FYB57_RS15085	COG2239	Acts as a magnesium transporter
FYB57_RS15100	COG1522	sequence-specific DNA binding
FYB57_RS15135	COG0330	HflC and HflK could
FYB57_RS15140	COG0330	HflC and HflK could
FYB57_RS15145	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FYB57_RS15150	COG1923	regulation of RNA biosynthetic process
FYB57_RS15160	COG1160	GTP binding
FYB57_RS15165	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FYB57_RS15170	COG2976	Protein conserved in bacteria
FYB57_RS15175	COG0124	histidyl-tRNA synthetase
FYB57_RS15190	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FYB57_RS15195	COG0105	UTP biosynthetic process
FYB57_RS15200	COG0525	valine-tRNA ligase activity
FYB57_RS15210	COG0336	Belongs to the RNA methyltransferase TrmD family
FYB57_RS15215	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FYB57_RS15220	COG0228	four-way junction DNA binding
FYB57_RS15225	COG0425	Belongs to the sulfur carrier protein TusA family
FYB57_RS15230	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FYB57_RS15295	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FYB57_RS15300	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FYB57_RS15300	COG0543	2 iron, 2 sulfur cluster binding
FYB57_RS15305	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FYB57_RS15310	COG2076	Multidrug Resistance protein
FYB57_RS15315	COG0633	Ferredoxin
FYB57_RS15315	COG3217	Mosc domain protein beta barrel domain protein
FYB57_RS15320	COG5285	phytanoyl-CoA dioxygenase
FYB57_RS15325	COG0662	Cupin 2, conserved barrel domain protein
FYB57_RS15335	COG0456	acetyltransferase
FYB57_RS15350	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FYB57_RS15380	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FYB57_RS15390	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FYB57_RS15395	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FYB57_RS15400	COG1760	l-serine dehydratase
FYB57_RS15405	COG1283	sodium-dependent phosphate transmembrane transporter activity
FYB57_RS15410	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FYB57_RS15415	COG0412	Dienelactone hydrolase
FYB57_RS15420	COG0428	transporter
FYB57_RS15430	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FYB57_RS15440	COG1845	cytochrome c oxidase, subunit III
FYB57_RS15445	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FYB57_RS15455	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FYB57_RS15455	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FYB57_RS15480	COG1942	4-Oxalocrotonate Tautomerase
FYB57_RS15490	COG4176	ABC-type proline glycine betaine transport system permease component
FYB57_RS15510	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FYB57_RS15515	COG2814	Major facilitator Superfamily
FYB57_RS15520	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FYB57_RS15525	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FYB57_RS15550	COG1846	Transcriptional regulator
FYB57_RS15555	COG2814	Major facilitator Superfamily
FYB57_RS15560	COG0495	leucyl-tRNA aminoacylation
FYB57_RS15575	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FYB57_RS15595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYB57_RS15600	COG2274	protein secretion by the type I secretion system
FYB57_RS15645	COG0427	acetyl-CoA hydrolase
FYB57_RS15655	COG1511	domain protein
FYB57_RS15655	COG3264	Mechanosensitive ion channel
FYB57_RS15660	COG0730	response to heat
FYB57_RS15675	COG2176	DNA-directed DNA polymerase activity
FYB57_RS15695	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FYB57_RS15700	COG3384	dioxygenase
FYB57_RS15715	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FYB57_RS15785	COG4964	Belongs to the GSP D family
FYB57_RS15830	COG1846	Transcriptional regulator
FYB57_RS15865	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FYB57_RS15875	COG2070	2-Nitropropane dioxygenase
FYB57_RS15880	COG2070	2-Nitropropane dioxygenase
FYB57_RS15890	COG2610	gluconate transmembrane transporter activity
FYB57_RS15905	COG1408	metallophosphoesterase
FYB57_RS15910	COG0493	'glutamate synthase
FYB57_RS15910	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FYB57_RS15915	COG2199	diguanylate cyclase activity
FYB57_RS15920	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FYB57_RS15955	COG2159	amidohydrolase
FYB57_RS15965	COG0583	DNA-binding transcription factor activity
FYB57_RS15980	COG1024	Enoyl-CoA hydratase
FYB57_RS15985	COG2186	Transcriptional regulator
FYB57_RS15990	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYB57_RS16000	COG0833	amino acid
FYB57_RS16010	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FYB57_RS16045	COG5265	(ABC) transporter
FYB57_RS16085	COG1971	Probably functions as a manganese efflux pump
FYB57_RS16090	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FYB57_RS16100	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FYB57_RS16105	COG2814	Major facilitator Superfamily
FYB57_RS16130	COG4608	Belongs to the ABC transporter superfamily
FYB57_RS16150	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FYB57_RS16160	COG3383	formate dehydrogenase (NAD+) activity
FYB57_RS16175	COG0747	negative chemotaxis
FYB57_RS16185	COG0625	glutathione transferase activity
FYB57_RS16215	COG1595	DNA-templated transcription, initiation
FYB57_RS16225	COG4774	siderophore transport
FYB57_RS16240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FYB57_RS16255	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FYB57_RS16260	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FYB57_RS16285	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYB57_RS16290	COG1024	Enoyl-CoA hydratase
FYB57_RS16325	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FYB57_RS16330	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FYB57_RS16335	COG1116	anion transmembrane transporter activity
FYB57_RS16345	COG3585	molybdate ion transport
FYB57_RS16405	COG0583	DNA-binding transcription factor activity
FYB57_RS16410	COG4948	Mandelate Racemase Muconate Lactonizing
FYB57_RS16415	COG3181	Tripartite tricarboxylate transporter family receptor
FYB57_RS16445	COG3181	Tripartite tricarboxylate transporter family receptor
FYB57_RS16480	COG4177	L-phenylalanine transmembrane transporter activity
FYB57_RS16505	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FYB57_RS16520	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FYB57_RS16525	COG1538	Outer membrane efflux protein
FYB57_RS16530	COG0577	efflux transmembrane transporter activity
FYB57_RS16530	COG1136	(ABC) transporter
FYB57_RS16535	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYB57_RS16550	COG0259	pyridoxamine-phosphate oxidase activity
FYB57_RS16555	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FYB57_RS16560	COG0579	oxidoreductase
FYB57_RS16570	COG0405	Gamma-glutamyltransferase
FYB57_RS16580	COG3181	Tripartite tricarboxylate transporter family receptor
FYB57_RS16590	COG0114	fumarate hydratase activity
FYB57_RS16595	COG0802	atpase or kinase
FYB57_RS16600	COG0860	N-Acetylmuramoyl-L-alanine amidase
FYB57_RS16605	COG0586	Pfam SNARE associated Golgi protein
FYB57_RS16610	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FYB57_RS16615	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FYB57_RS16620	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FYB57_RS16635	COG0617	tRNA 3'-terminal CCA addition
FYB57_RS16670	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
FYB57_RS16680	COG1024	Enoyl-CoA hydratase
FYB57_RS16690	COG2188	Transcriptional regulator
FYB57_RS16695	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FYB57_RS16710	COG0752	glycyl-tRNA synthetase alpha subunit
FYB57_RS16715	COG0751	glycine-tRNA ligase activity
FYB57_RS16720	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FYB57_RS16725	COG0204	Acyl-transferase
FYB57_RS16755	COG0242	peptide deformylase activity
FYB57_RS16765	COG0700	Nucleoside recognition
FYB57_RS16770	COG0469	pyruvate kinase activity
FYB57_RS16775	COG1929	Belongs to the glycerate kinase type-1 family
FYB57_RS16785	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FYB57_RS16790	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FYB57_RS16795	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FYB57_RS16805	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FYB57_RS16815	COG2154	pterin-4-alpha-carbinolamine dehydratase
FYB57_RS16820	COG2885	chlorophyll binding
FYB57_RS16830	COG0667	Aldo Keto reductase
FYB57_RS16840	COG3181	Tripartite tricarboxylate transporter family receptor
FYB57_RS16860	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FYB57_RS16865	COG0288	reversible hydration of carbon dioxide
FYB57_RS16885	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FYB57_RS16895	COG4829	muconolactone delta-isomerase
FYB57_RS16900	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FYB57_RS16910	COG1414	Transcriptional regulator
FYB57_RS16915	COG1028	Short-chain dehydrogenase reductase Sdr
FYB57_RS16920	COG2031	fatty acid transporter
FYB57_RS16925	COG1250	3-hydroxyacyl-CoA dehydrogenase
FYB57_RS16935	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FYB57_RS16940	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FYB57_RS16955	COG0129	dihydroxy-acid dehydratase activity
FYB57_RS16960	COG1609	Transcriptional regulator
FYB57_RS16985	COG4106	trans-aconitate 2-methyltransferase activity
FYB57_RS17000	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FYB57_RS17035	COG0163	prenyltransferase activity
FYB57_RS17040	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FYB57_RS17045	COG2890	protein-(glutamine-N5) methyltransferase activity
FYB57_RS17050	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FYB57_RS17055	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FYB57_RS17070	COG3712	iron ion homeostasis
FYB57_RS17100	COG0659	secondary active sulfate transmembrane transporter activity
FYB57_RS17120	COG1028	Short-chain dehydrogenase reductase Sdr
FYB57_RS17130	COG4774	siderophore transport
FYB57_RS17140	COG1595	DNA-templated transcription, initiation
FYB57_RS17155	COG0142	geranyltranstransferase activity
FYB57_RS17160	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FYB57_RS17165	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FYB57_RS17170	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FYB57_RS17175	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FYB57_RS17195	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FYB57_RS17195	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FYB57_RS17200	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FYB57_RS17215	COG0583	DNA-binding transcription factor activity
FYB57_RS17220	COG0861	Integral membrane protein TerC family
FYB57_RS17235	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FYB57_RS17240	COG0793	Belongs to the peptidase S41A family
FYB57_RS17245	COG4942	peptidase
FYB57_RS17250	COG0588	phosphoglycerate mutase activity
FYB57_RS17260	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FYB57_RS17265	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FYB57_RS17270	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FYB57_RS17275	COG3181	Tripartite tricarboxylate transporter family receptor
FYB57_RS17290	COG2226	methyltransferase
FYB57_RS17295	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
FYB57_RS17300	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FYB57_RS17310	COG2204	response regulator
FYB57_RS17315	COG5000	phosphorelay sensor kinase activity
FYB57_RS17325	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FYB57_RS17325	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FYB57_RS17360	COG2188	Transcriptional regulator
FYB57_RS17375	COG0583	DNA-binding transcription factor activity
FYB57_RS17380	COG1012	belongs to the aldehyde dehydrogenase family
FYB57_RS17400	COG0546	phosphoglycolate phosphatase activity
FYB57_RS17415	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FYB57_RS17420	COG0242	peptide deformylase activity
FYB57_RS17430	COG1522	sequence-specific DNA binding
FYB57_RS17435	COG2879	small protein
FYB57_RS17440	COG1966	Carbon starvation protein
FYB57_RS17470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYB57_RS17475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FYB57_RS17480	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FYB57_RS17485	COG3181	Tripartite tricarboxylate transporter family receptor
FYB57_RS17550	COG1172	Belongs to the binding-protein-dependent transport system permease family
FYB57_RS17585	COG0640	Transcriptional regulator
FYB57_RS17625	COG0735	belongs to the Fur family
FYB57_RS17630	COG2207	Transcriptional regulator
FYB57_RS17635	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FYB57_RS17640	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FYB57_RS17645	COG0513	Belongs to the DEAD box helicase family
FYB57_RS17670	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FYB57_RS17685	COG1305	Transglutaminase-like
FYB57_RS17725	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FYB57_RS17730	COG1950	PFAM Membrane protein of
FYB57_RS17755	COG0024	Methionine aminopeptidase
FYB57_RS17760	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FYB57_RS17770	COG1560	Kdo2-lipid A biosynthetic process
FYB57_RS17775	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FYB57_RS17785	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FYB57_RS17820	COG0735	belongs to the Fur family
FYB57_RS17825	COG0523	cobalamin synthesis protein
FYB57_RS17840	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FYB57_RS17850	COG2096	Adenosyltransferase
FYB57_RS17855	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FYB57_RS17860	COG0321	lipoyl(octanoyl) transferase activity
FYB57_RS17870	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FYB57_RS17875	COG1686	Belongs to the peptidase S11 family
FYB57_RS17900	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FYB57_RS17910	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FYB57_RS17920	COG0859	PFAM glycosyl transferase family 9
FYB57_RS17955	COG0477	Major facilitator Superfamily
FYB57_RS17970	COG3568	Endonuclease Exonuclease Phosphatase
FYB57_RS17975	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FYB57_RS18005	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FYB57_RS18010	COG1956	GAF domain-containing protein
FYB57_RS18015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FYB57_RS18030	COG2186	Transcriptional regulator
FYB57_RS18035	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FYB57_RS18050	COG1840	ABC-type Fe3 transport system, periplasmic component
FYB57_RS18090	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FYB57_RS18095	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FYB57_RS18100	COG1086	Polysaccharide biosynthesis protein
FYB57_RS18130	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FYB57_RS18140	COG1028	Short-chain dehydrogenase reductase Sdr
FYB57_RS18145	COG1012	belongs to the aldehyde dehydrogenase family
FYB57_RS18170	COG1522	sequence-specific DNA binding
FYB57_RS18175	COG3781	membrane
FYB57_RS18215	COG2200	EAL domain
FYB57_RS18225	COG0592	DNA-directed DNA polymerase activity
FYB57_RS18230	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FYB57_RS18235	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FYB57_RS18240	COG0594	ribonuclease P activity
FYB57_RS18245	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FYB57_RS18250	COG0706	membrane insertase activity
FYB57_RS18255	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FYB57_RS18260	COG1473	amidohydrolase
FYB57_RS18265	COG4608	Belongs to the ABC transporter superfamily
FYB57_RS18270	COG0444	Belongs to the ABC transporter superfamily
FYB57_RS18275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FYB57_RS18280	COG0601	transmembrane transport
FYB57_RS18290	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FYB57_RS18295	COG1505	serine-type exopeptidase activity
FYB57_RS18305	COG0281	malic enzyme
FYB57_RS18305	COG0280	phosphate acetyltransferase
FYB57_RS18335	COG0436	Aminotransferase
FYB57_RS18340	COG1278	Cold shock