locus-tag	class	description
CWR63_RS00010	COG0357	Ribosomal RNA small subunit methyltransferase G
CWR63_RS00015	COG1192	Involved in chromosome partitioning
CWR63_RS00025	COG1475	DNA binding
CWR63_RS00030	COG0252	asparaginase activity
CWR63_RS00050	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CWR63_RS00060	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CWR63_RS00075	COG0081	regulation of translation
CWR63_RS00080	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CWR63_RS00085	COG0222	ribosome binding
CWR63_RS00095	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CWR63_RS00130	COG1230	cation diffusion facilitator family transporter
CWR63_RS00140	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CWR63_RS00145	COG0049	tRNA binding
CWR63_RS00155	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CWR63_RS00165	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CWR63_RS00175	COG0089	rRNA binding
CWR63_RS00180	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CWR63_RS00190	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CWR63_RS00195	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CWR63_RS00200	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CWR63_RS00205	COG0255	Belongs to the universal ribosomal protein uL29 family
CWR63_RS00210	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CWR63_RS00230	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CWR63_RS00235	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CWR63_RS00240	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CWR63_RS00245	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CWR63_RS00250	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CWR63_RS00260	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CWR63_RS00265	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CWR63_RS00270	COG1841	ribosomal large subunit assembly
CWR63_RS00280	COG0201	protein transport
CWR63_RS00285	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CWR63_RS00290	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CWR63_RS00295	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CWR63_RS00300	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CWR63_RS00305	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CWR63_RS00310	COG0202	RNA polymerase activity
CWR63_RS00315	COG0203	ribosomal protein L17
CWR63_RS00320	COG0537	adenosine 5'-monophosphoramidase activity
CWR63_RS00325	COG1324	tolerance protein
CWR63_RS00330	COG4232	protein-disulfide reductase activity
CWR63_RS00345	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CWR63_RS00355	COG1333	cytochrome c biogenesis protein
CWR63_RS00360	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CWR63_RS00385	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CWR63_RS00390	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CWR63_RS00410	COG2814	Major facilitator Superfamily
CWR63_RS00455	COG0402	S-adenosylhomocysteine deaminase activity
CWR63_RS00465	COG0438	transferase activity, transferring glycosyl groups
CWR63_RS00485	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CWR63_RS00515	COG2186	Transcriptional regulator
CWR63_RS00535	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CWR63_RS00540	COG1956	GAF domain-containing protein
CWR63_RS00545	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CWR63_RS00575	COG0531	amino acid
CWR63_RS00605	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CWR63_RS00610	COG3568	Endonuclease Exonuclease Phosphatase
CWR63_RS00615	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CWR63_RS00635	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CWR63_RS00645	COG0367	asparagine synthase
CWR63_RS00665	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CWR63_RS00670	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CWR63_RS00710	COG0367	asparagine synthase
CWR63_RS00715	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CWR63_RS00740	COG0367	asparagine synthase
CWR63_RS00750	COG0438	transferase activity, transferring glycosyl groups
CWR63_RS00770	COG0438	transferase activity, transferring glycosyl groups
CWR63_RS00775	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CWR63_RS00780	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CWR63_RS00810	COG0859	PFAM glycosyl transferase family 9
CWR63_RS00840	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CWR63_RS00845	COG1127	ABC transporter
CWR63_RS00865	COG1686	Belongs to the peptidase S11 family
CWR63_RS00905	COG2096	Adenosyltransferase
CWR63_RS00930	COG0523	cobalamin synthesis protein
CWR63_RS00935	COG0735	belongs to the Fur family
CWR63_RS00940	COG1121	(ABC) transporter
CWR63_RS00950	COG0803	Belongs to the bacterial solute-binding protein 9 family
CWR63_RS00960	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CWR63_RS00970	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CWR63_RS00980	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CWR63_RS00985	COG1560	Kdo2-lipid A biosynthetic process
CWR63_RS00995	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CWR63_RS01015	COG1950	PFAM Membrane protein of
CWR63_RS01025	COG0583	DNA-binding transcription factor activity
CWR63_RS01035	COG0477	Major facilitator Superfamily
CWR63_RS01060	COG0513	Belongs to the DEAD box helicase family
CWR63_RS01070	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CWR63_RS01075	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CWR63_RS01090	COG0735	belongs to the Fur family
CWR63_RS01110	COG0438	transferase activity, transferring glycosyl groups
CWR63_RS01135	COG0640	Transcriptional regulator
CWR63_RS01195	COG0583	DNA-binding transcription factor activity
CWR63_RS01210	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CWR63_RS01215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CWR63_RS01220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWR63_RS01235	COG0758	DNA mediated transformation
CWR63_RS01240	COG1522	sequence-specific DNA binding
CWR63_RS01250	COG0242	peptide deformylase activity
CWR63_RS01265	COG0546	phosphoglycolate phosphatase activity
CWR63_RS01285	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CWR63_RS01290	COG1942	4-Oxalocrotonate Tautomerase
CWR63_RS01295	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CWR63_RS01330	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CWR63_RS01330	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CWR63_RS01340	COG5000	phosphorelay sensor kinase activity
CWR63_RS01345	COG2204	response regulator
CWR63_RS01370	COG2068	MobA-Related Protein
CWR63_RS01385	COG0596	Alpha beta hydrolase
CWR63_RS01390	COG2309	aminopeptidase activity
CWR63_RS01395	COG1335	isochorismatase
CWR63_RS01420	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CWR63_RS01445	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CWR63_RS01450	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CWR63_RS01470	COG2226	methyltransferase
CWR63_RS01485	COG3181	Tripartite tricarboxylate transporter family receptor
CWR63_RS01495	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CWR63_RS01500	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CWR63_RS01505	COG1054	Belongs to the UPF0176 family
CWR63_RS01515	COG4942	peptidase
CWR63_RS01520	COG0793	Belongs to the peptidase S41A family
CWR63_RS01525	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CWR63_RS01545	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CWR63_RS01580	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CWR63_RS01585	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CWR63_RS01590	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CWR63_RS01600	COG0142	geranyltranstransferase activity
CWR63_RS01610	COG0583	DNA-binding transcription factor activity
CWR63_RS01620	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
CWR63_RS01625	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CWR63_RS01640	COG2994	toxin metabolic process
CWR63_RS01650	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CWR63_RS01655	COG2274	protein secretion by the type I secretion system
CWR63_RS01660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CWR63_RS01665	COG1538	Outer membrane efflux protein
CWR63_RS01680	COG0765	amino acid transport
CWR63_RS01685	COG0765	amino acid transport
CWR63_RS01690	COG1126	abc transporter atp-binding protein
CWR63_RS01710	COG1028	Short-chain dehydrogenase reductase Sdr
CWR63_RS01720	COG1802	Transcriptional regulator
CWR63_RS01735	COG1802	Transcriptional regulator
CWR63_RS01745	COG0318	PFAM AMP-dependent synthetase and ligase
CWR63_RS01755	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CWR63_RS01785	COG0583	DNA-binding transcription factor activity
CWR63_RS01790	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR63_RS01795	COG2301	Belongs to the HpcH HpaI aldolase family
CWR63_RS01800	COG2188	Transcriptional regulator
CWR63_RS01845	COG0583	DNA-binding transcription factor activity
CWR63_RS01850	COG1024	Enoyl-CoA hydratase
CWR63_RS01885	COG1028	Short-chain dehydrogenase reductase Sdr
CWR63_RS01900	COG1902	pentaerythritol trinitrate reductase activity
CWR63_RS01925	COG0745	RESPONSE REGULATOR receiver
CWR63_RS01965	COG2890	protein-(glutamine-N5) methyltransferase activity
CWR63_RS01970	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CWR63_RS01980	COG3181	Tripartite tricarboxylate transporter family receptor
CWR63_RS02050	COG4211	Belongs to the binding-protein-dependent transport system permease family
CWR63_RS02060	COG0683	leucine binding
CWR63_RS02065	COG0154	amidase activity
CWR63_RS02070	COG0288	reversible hydration of carbon dioxide
CWR63_RS02090	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CWR63_RS02105	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CWR63_RS02115	COG1414	Transcriptional regulator
CWR63_RS02120	COG1028	Short-chain dehydrogenase reductase Sdr
CWR63_RS02125	COG2031	fatty acid transporter
CWR63_RS02130	COG1250	3-hydroxyacyl-CoA dehydrogenase
CWR63_RS02160	COG2808	Putative FMN-binding domain
CWR63_RS02165	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CWR63_RS02170	COG0747	negative chemotaxis
CWR63_RS02175	COG0657	acetylesterase activity
CWR63_RS02185	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CWR63_RS02190	COG2207	Transcriptional regulator
CWR63_RS02215	COG1538	Outer membrane efflux protein
CWR63_RS02230	COG0583	DNA-binding transcription factor activity
CWR63_RS02235	COG0628	permease
CWR63_RS02245	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CWR63_RS02250	COG0251	oxidation-reduction process
CWR63_RS02260	COG0330	HflC and HflK could
CWR63_RS02265	COG3422	double-strand break repair
CWR63_RS02280	COG0583	DNA-binding transcription factor activity
CWR63_RS02315	COG3181	Tripartite tricarboxylate transporter family receptor
CWR63_RS02320	COG0318	PFAM AMP-dependent synthetase and ligase
CWR63_RS02325	COG1414	Transcriptional regulator
CWR63_RS02330	COG1024	Enoyl-CoA hydratase
CWR63_RS02335	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CWR63_RS02340	COG3181	Tripartite tricarboxylate transporter family receptor
CWR63_RS02345	COG0604	alcohol dehydrogenase
CWR63_RS02350	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR63_RS02355	COG0583	DNA-binding transcription factor activity
CWR63_RS02365	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR63_RS02380	COG0251	oxidation-reduction process
CWR63_RS02390	COG2031	fatty acid transporter
CWR63_RS02420	COG1278	Cold shock
CWR63_RS02425	COG0583	DNA-binding transcription factor activity
CWR63_RS02435	COG3119	arylsulfatase activity
CWR63_RS02450	COG1228	amidohydrolase
CWR63_RS02455	COG0523	cobalamin synthesis protein
CWR63_RS02460	COG1819	glycosyl
CWR63_RS02545	COG0625	glutathione transferase activity
CWR63_RS02560	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CWR63_RS02565	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CWR63_RS02570	COG1652	LysM domain
CWR63_RS02595	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR63_RS02600	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CWR63_RS02635	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CWR63_RS02690	COG0583	DNA-binding transcription factor activity
CWR63_RS02695	COG3181	Tripartite tricarboxylate transporter family receptor
CWR63_RS02705	COG1024	Enoyl-CoA hydratase
CWR63_RS02710	COG3181	Tripartite tricarboxylate transporter family receptor
CWR63_RS02735	COG0028	Belongs to the TPP enzyme family
CWR63_RS02745	COG1250	3-hydroxyacyl-CoA dehydrogenase
CWR63_RS02745	COG1024	Enoyl-CoA hydratase
CWR63_RS02750	COG3181	Tripartite tricarboxylate transporter family receptor
CWR63_RS02755	COG1414	Transcriptional regulator
CWR63_RS02775	COG0318	PFAM AMP-dependent synthetase and ligase
CWR63_RS02780	COG1609	Transcriptional regulator
CWR63_RS02810	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CWR63_RS02815	COG1024	Enoyl-CoA hydratase
CWR63_RS02830	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR63_RS02835	COG3181	Tripartite tricarboxylate transporter family receptor
CWR63_RS02840	COG0583	DNA-binding transcription factor activity
CWR63_RS02855	COG1960	acyl-CoA dehydrogenase activity
CWR63_RS02870	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CWR63_RS02880	COG3976	FMN-binding domain protein
CWR63_RS02880	COG1053	succinate dehydrogenase
CWR63_RS02915	COG0683	leucine binding
CWR63_RS02925	COG1309	transcriptional regulator
CWR63_RS02945	COG1028	Short-chain dehydrogenase reductase Sdr
CWR63_RS02950	COG1960	acyl-CoA dehydrogenase activity
CWR63_RS02955	COG1028	Short-chain dehydrogenase reductase Sdr
CWR63_RS02960	COG0318	PFAM AMP-dependent synthetase and ligase
CWR63_RS02970	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CWR63_RS02980	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CWR63_RS02985	COG1053	succinate dehydrogenase
CWR63_RS02995	COG2030	dehydratase
CWR63_RS03005	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR63_RS03010	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR63_RS03015	COG3181	Tripartite tricarboxylate transporter family receptor
CWR63_RS03040	COG0559	Belongs to the binding-protein-dependent transport system permease family
CWR63_RS03060	COG0446	pyridine nucleotide-disulphide oxidoreductase
CWR63_RS03060	COG1902	pentaerythritol trinitrate reductase activity
CWR63_RS03075	COG0427	acetyl-CoA hydrolase
CWR63_RS03080	COG0318	PFAM AMP-dependent synthetase and ligase
CWR63_RS03095	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CWR63_RS03115	COG0183	Belongs to the thiolase family
CWR63_RS03120	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CWR63_RS03130	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR63_RS03135	COG0583	DNA-binding transcription factor activity
CWR63_RS03140	COG1960	acyl-CoA dehydrogenase activity
CWR63_RS03155	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
CWR63_RS03180	COG1309	transcriptional regulator
CWR63_RS03190	COG1024	Enoyl-CoA hydratase
CWR63_RS03210	COG1024	Enoyl-CoA hydratase
CWR63_RS03215	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR63_RS03220	COG3181	Tripartite tricarboxylate transporter family receptor
CWR63_RS03225	COG1454	alcohol dehydrogenase
CWR63_RS03230	COG1024	Enoyl-CoA hydratase
CWR63_RS03250	COG1012	belongs to the aldehyde dehydrogenase family
CWR63_RS03255	COG0431	NADPH-dependent FMN reductase
CWR63_RS03260	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CWR63_RS03265	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CWR63_RS03280	COG1414	Transcriptional regulator
CWR63_RS03285	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CWR63_RS03290	COG1028	Short-chain dehydrogenase reductase Sdr
CWR63_RS03295	COG3181	Tripartite tricarboxylate transporter family receptor
CWR63_RS03320	COG0318	PFAM AMP-dependent synthetase and ligase
CWR63_RS03340	COG1024	Enoyl-CoA hydratase
CWR63_RS03350	COG1960	acyl-CoA dehydrogenase activity
CWR63_RS03355	COG1024	Enoyl-CoA hydratase
CWR63_RS03360	COG0183	Belongs to the thiolase family
CWR63_RS03365	COG3181	Tripartite tricarboxylate transporter family receptor
CWR63_RS03380	COG0583	DNA-binding transcription factor activity
CWR63_RS03385	COG2267	carboxylic ester hydrolase activity
CWR63_RS03400	COG0625	glutathione transferase activity
CWR63_RS03405	COG3181	Tripartite tricarboxylate transporter family receptor
CWR63_RS03415	COG2186	Transcriptional regulator
CWR63_RS03420	COG1012	belongs to the aldehyde dehydrogenase family
CWR63_RS03425	COG0626	cystathionine gamma-synthase activity
CWR63_RS03465	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CWR63_RS03470	COG0436	Aminotransferase
CWR63_RS03475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWR63_RS03480	COG0765	amino acid transport
CWR63_RS03490	COG1473	amidohydrolase
CWR63_RS03495	COG1414	Transcriptional regulator
CWR63_RS03505	COG0154	amidase activity
CWR63_RS03565	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CWR63_RS03580	COG3135	benzoate transporter
CWR63_RS03625	COG5444	nuclease activity
CWR63_RS03745	COG3468	outer membrane autotransporter barrel domain protein
CWR63_RS03810	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CWR63_RS03855	COG0489	protein tyrosine kinase activity
CWR63_RS03900	COG2081	HI0933 family
CWR63_RS03905	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CWR63_RS03920	COG0509	glycine decarboxylation via glycine cleavage system
CWR63_RS03945	COG1024	Enoyl-CoA hydratase
CWR63_RS03965	COG4172	Belongs to the ABC transporter superfamily
CWR63_RS03970	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CWR63_RS03975	COG0601	transmembrane transport
CWR63_RS03980	COG0747	negative chemotaxis
CWR63_RS03990	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CWR63_RS04020	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CWR63_RS04025	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CWR63_RS04040	COG0438	transferase activity, transferring glycosyl groups
CWR63_RS04055	COG0438	transferase activity, transferring glycosyl groups
CWR63_RS04060	COG0438	transferase activity, transferring glycosyl groups
CWR63_RS04065	COG0166	Belongs to the GPI family
CWR63_RS04080	COG0277	FAD linked oxidase domain protein
CWR63_RS04085	COG0745	RESPONSE REGULATOR receiver
CWR63_RS04090	COG0642	Histidine kinase
CWR63_RS04095	COG1368	sulfuric ester hydrolase activity
CWR63_RS04180	COG0012	GTP binding
CWR63_RS04195	COG0745	RESPONSE REGULATOR receiver
CWR63_RS04200	COG3181	Tripartite tricarboxylate transporter family receptor
CWR63_RS04205	COG1309	transcriptional regulator
CWR63_RS04215	COG2814	Major facilitator Superfamily
CWR63_RS04240	COG0281	malic enzyme
CWR63_RS04240	COG0280	phosphate acetyltransferase
CWR63_RS04250	COG0601	transmembrane transport
CWR63_RS04255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CWR63_RS04260	COG4172	Belongs to the ABC transporter superfamily
CWR63_RS04275	COG0583	DNA-binding transcription factor activity
CWR63_RS04290	COG0640	Transcriptional regulator
CWR63_RS04305	COG3135	benzoate transporter
CWR63_RS04310	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CWR63_RS04315	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CWR63_RS04320	COG0742	ribosomal rna small subunit methyltransferase
CWR63_RS04335	COG3639	organic phosphonate transmembrane transporter activity
CWR63_RS04340	COG3639	organic phosphonate transmembrane transporter activity
CWR63_RS04370	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CWR63_RS04375	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CWR63_RS04385	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CWR63_RS04390	COG1546	Belongs to the CinA family
CWR63_RS04390	COG1058	Belongs to the CinA family
CWR63_RS04395	COG0284	orotidine-5'-phosphate decarboxylase activity
CWR63_RS04400	COG1252	NADH dehydrogenase
CWR63_RS04425	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CWR63_RS04445	COG1053	succinate dehydrogenase
CWR63_RS04455	COG0583	DNA-binding transcription factor activity
CWR63_RS04460	COG1053	succinate dehydrogenase
CWR63_RS04465	COG3181	Tripartite tricarboxylate transporter family receptor
CWR63_RS04470	COG1414	Transcriptional regulator
CWR63_RS04485	COG1335	isochorismatase
CWR63_RS04500	COG0405	Gamma-glutamyltransferase
CWR63_RS04515	COG1960	acyl-CoA dehydrogenase activity
CWR63_RS04520	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR63_RS04525	COG3181	Tripartite tricarboxylate transporter family receptor
CWR63_RS04530	COG0583	DNA-binding transcription factor activity
CWR63_RS04555	COG3181	Tripartite tricarboxylate transporter family receptor
CWR63_RS04560	COG0583	DNA-binding transcription factor activity
CWR63_RS04565	COG2199	diguanylate cyclase activity
CWR63_RS04620	COG1250	3-hydroxyacyl-CoA dehydrogenase
CWR63_RS04620	COG1024	Enoyl-CoA hydratase
CWR63_RS04625	COG0318	PFAM AMP-dependent synthetase and ligase
CWR63_RS04640	COG1024	Enoyl-CoA hydratase
CWR63_RS04645	COG1024	Enoyl-CoA hydratase
CWR63_RS04650	COG0318	PFAM AMP-dependent synthetase and ligase
CWR63_RS04655	COG1960	acyl-CoA dehydrogenase activity
CWR63_RS04695	COG3685	Protein conserved in bacteria
CWR63_RS04705	COG0387	Pfam Sodium calcium exchanger
CWR63_RS04710	COG3795	YCII-related domain
CWR63_RS04715	COG2188	Transcriptional regulator
CWR63_RS04735	COG0154	amidase activity
CWR63_RS04740	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR63_RS04745	COG1024	Enoyl-CoA hydratase
CWR63_RS04755	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CWR63_RS04770	COG1028	Short-chain dehydrogenase reductase Sdr
CWR63_RS04775	COG1414	Transcriptional regulator
CWR63_RS04790	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CWR63_RS04795	COG0251	oxidation-reduction process
CWR63_RS04800	COG0559	Belongs to the binding-protein-dependent transport system permease family
CWR63_RS04820	COG1902	pentaerythritol trinitrate reductase activity
CWR63_RS04825	COG0583	DNA-binding transcription factor activity
CWR63_RS04835	COG0590	tRNA wobble adenosine to inosine editing
CWR63_RS04840	COG2807	transmembrane transport
CWR63_RS04845	COG0307	riboflavin synthase, alpha
CWR63_RS04850	COG3181	Tripartite tricarboxylate transporter family receptor
CWR63_RS04855	COG1522	sequence-specific DNA binding
CWR63_RS04865	COG0318	PFAM AMP-dependent synthetase and ligase
CWR63_RS04875	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CWR63_RS04915	COG1418	mRNA catabolic process
CWR63_RS04925	COG1335	isochorismatase
CWR63_RS04950	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CWR63_RS04955	COG2274	protein secretion by the type I secretion system
CWR63_RS04965	COG1538	Outer membrane efflux protein
CWR63_RS04970	COG0493	'glutamate synthase
CWR63_RS04970	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CWR63_RS04980	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CWR63_RS04990	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR63_RS05000	COG1309	transcriptional regulator
CWR63_RS05005	COG1960	acyl-CoA dehydrogenase activity
CWR63_RS05010	COG1028	Short-chain dehydrogenase reductase Sdr
CWR63_RS05015	COG2076	Multidrug Resistance protein
CWR63_RS05020	COG1309	transcriptional regulator
CWR63_RS05040	COG0840	transmembrane signaling receptor activity
CWR63_RS05055	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CWR63_RS05080	COG1012	belongs to the aldehyde dehydrogenase family
CWR63_RS05090	COG1024	Enoyl-CoA hydratase
CWR63_RS05100	COG2203	Gaf domain
CWR63_RS05100	COG2199	diguanylate cyclase activity
CWR63_RS05120	COG0154	amidase activity
CWR63_RS05125	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CWR63_RS05125	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CWR63_RS05150	COG3945	hemerythrin HHE cation binding domain
CWR63_RS05165	COG2169	Transcriptional regulator
CWR63_RS05165	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CWR63_RS05185	COG1271	oxidase subunit
CWR63_RS05190	COG1294	oxidase, subunit
CWR63_RS05200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CWR63_RS05230	COG0596	Alpha beta hydrolase
CWR63_RS05235	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CWR63_RS05270	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CWR63_RS05275	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CWR63_RS05285	COG2070	2-Nitropropane dioxygenase
CWR63_RS05300	COG2207	Transcriptional regulator
CWR63_RS05300	COG1917	Cupin 2, conserved barrel domain protein
CWR63_RS05320	COG2900	Belongs to the SlyX family
CWR63_RS05330	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CWR63_RS05360	COG0583	DNA-binding transcription factor activity
CWR63_RS05365	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR63_RS05375	COG0583	DNA-binding transcription factor activity
CWR63_RS05400	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CWR63_RS05410	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CWR63_RS05415	COG1845	cytochrome c oxidase, subunit III
CWR63_RS05420	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CWR63_RS05425	COG0640	Transcriptional regulator
CWR63_RS05490	COG1666	GTP binding
CWR63_RS05515	COG1028	Short-chain dehydrogenase reductase Sdr
CWR63_RS05525	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CWR63_RS05530	COG1845	cytochrome c oxidase, subunit III
CWR63_RS05535	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CWR63_RS05540	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CWR63_RS05545	COG0477	Major facilitator Superfamily
CWR63_RS05560	COG5006	permease, DMT superfamily
CWR63_RS05580	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CWR63_RS05595	COG3383	formate dehydrogenase (NAD+) activity
CWR63_RS05615	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CWR63_RS05620	COG0303	'Molybdopterin
CWR63_RS05625	COG0521	Mo-molybdopterin cofactor biosynthetic process
CWR63_RS05635	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CWR63_RS05650	COG0412	Dienelactone hydrolase
CWR63_RS05660	COG0678	peroxiredoxin activity
CWR63_RS05670	COG0697	spore germination
CWR63_RS05715	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CWR63_RS05720	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CWR63_RS05725	COG1335	isochorismatase
CWR63_RS05730	COG0523	cobalamin synthesis protein
CWR63_RS05735	COG3181	Tripartite tricarboxylate transporter family receptor
CWR63_RS05750	COG3181	Tripartite tricarboxylate transporter family receptor
CWR63_RS05760	COG1802	Transcriptional regulator
CWR63_RS05780	COG0667	Aldo Keto reductase
CWR63_RS05790	COG4535	Mg2 and Co2 transporter CorC
CWR63_RS05800	COG1702	phosphate starvation-inducible protein PhoH
CWR63_RS05815	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CWR63_RS05820	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CWR63_RS05825	COG1862	Preprotein translocase
CWR63_RS05830	COG0343	queuine tRNA-ribosyltransferase activity
CWR63_RS05840	COG2027	D-alanyl-D-alanine carboxypeptidase
CWR63_RS05885	COG0741	lytic transglycosylase activity
CWR63_RS05895	COG0436	Aminotransferase
CWR63_RS05905	COG0280	phosphate acetyltransferase
CWR63_RS05905	COG0281	malic enzyme
CWR63_RS05915	COG2732	(Barnase) inhibitor
CWR63_RS05920	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CWR63_RS05925	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CWR63_RS05930	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CWR63_RS05940	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CWR63_RS05945	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CWR63_RS05960	COG0625	glutathione transferase activity
CWR63_RS05990	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CWR63_RS06000	COG0306	phosphate transporter
CWR63_RS06005	COG0521	Mo-molybdopterin cofactor biosynthetic process
CWR63_RS06015	COG0739	heme binding
CWR63_RS06025	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CWR63_RS06075	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CWR63_RS06100	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CWR63_RS06105	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CWR63_RS06110	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CWR63_RS06115	COG0009	L-threonylcarbamoyladenylate synthase
CWR63_RS06120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWR63_RS06125	COG1414	Transcriptional regulator
CWR63_RS06140	COG0765	amino acid transport
CWR63_RS06145	COG1126	abc transporter atp-binding protein
CWR63_RS06165	COG0028	Belongs to the TPP enzyme family
CWR63_RS06170	COG0583	DNA-binding transcription factor activity
CWR63_RS06175	COG4974	Belongs to the 'phage' integrase family
CWR63_RS06180	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CWR63_RS06185	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CWR63_RS06195	COG1686	Belongs to the peptidase S11 family
CWR63_RS06205	COG2814	Major facilitator Superfamily
CWR63_RS06215	COG1074	ATP-dependent DNA helicase activity
CWR63_RS06225	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CWR63_RS06240	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR63_RS06245	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CWR63_RS06255	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CWR63_RS06265	COG0505	Belongs to the CarA family
CWR63_RS06270	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CWR63_RS06305	COG0613	PHP domain protein
CWR63_RS06320	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CWR63_RS06320	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CWR63_RS06325	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CWR63_RS06330	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CWR63_RS06330	COG0047	phosphoribosylformylglycinamidine synthase activity
CWR63_RS06335	COG3064	Membrane
CWR63_RS06335	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CWR63_RS06335	COG3210	domain, Protein
CWR63_RS06355	COG3181	Tripartite tricarboxylate transporter family receptor
CWR63_RS06375	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CWR63_RS06395	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CWR63_RS06400	COG2197	response regulator
CWR63_RS06440	COG1061	Type III restriction enzyme res subunit
CWR63_RS06445	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CWR63_RS06465	COG0477	Major facilitator Superfamily
CWR63_RS06470	COG2814	Major facilitator Superfamily
CWR63_RS06485	COG0625	glutathione transferase activity
CWR63_RS06500	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CWR63_RS06515	COG3618	amidohydrolase
CWR63_RS06530	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR63_RS06550	COG2079	MmgE PrpD family protein
CWR63_RS06555	COG1012	belongs to the aldehyde dehydrogenase family
CWR63_RS06590	COG1280	lysine exporter protein (LysE YggA)
CWR63_RS06605	COG0747	negative chemotaxis
CWR63_RS06610	COG0601	transmembrane transport
CWR63_RS06620	COG4172	Belongs to the ABC transporter superfamily
CWR63_RS06625	COG1609	Transcriptional regulator
CWR63_RS06640	COG0789	Transcriptional regulator
CWR63_RS06665	COG2188	Transcriptional regulator
CWR63_RS06670	COG3181	Tripartite tricarboxylate transporter family receptor
CWR63_RS06690	COG1802	Transcriptional regulator
CWR63_RS06710	COG0842	Transport permease protein
CWR63_RS06735	COG0656	L-ascorbic acid biosynthetic process
CWR63_RS06740	COG3284	Transcriptional regulator
CWR63_RS06745	COG1012	belongs to the aldehyde dehydrogenase family
CWR63_RS06760	COG2733	membrane
CWR63_RS06765	COG0583	DNA-binding transcription factor activity
CWR63_RS06770	COG0384	phenazine biosynthesis protein PhzF
CWR63_RS06775	COG5507	3-demethylubiquinone-9 3-methyltransferase
CWR63_RS06810	COG0659	secondary active sulfate transmembrane transporter activity
CWR63_RS06835	COG1132	(ABC) transporter
CWR63_RS06875	COG2207	Transcriptional regulator
CWR63_RS06910	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CWR63_RS06915	COG1280	lysine exporter protein (LysE YggA)
CWR63_RS06935	COG0625	glutathione transferase activity
CWR63_RS06950	COG0697	spore germination
CWR63_RS06985	COG3246	L-lysine catabolic process to acetate
CWR63_RS06990	COG1250	3-hydroxyacyl-CoA dehydrogenase
CWR63_RS06995	COG0583	DNA-binding transcription factor activity
CWR63_RS07010	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CWR63_RS07015	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CWR63_RS07020	COG3622	Belongs to the hyi family
CWR63_RS07030	COG0129	dihydroxy-acid dehydratase activity
CWR63_RS07045	COG0129	dihydroxy-acid dehydratase activity
CWR63_RS07050	COG3181	Tripartite tricarboxylate transporter family receptor
CWR63_RS07060	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CWR63_RS07075	COG2188	Transcriptional regulator
CWR63_RS07085	COG0583	DNA-binding transcription factor activity
CWR63_RS07095	COG0501	Belongs to the peptidase M48B family
CWR63_RS07105	COG2814	Major facilitator Superfamily
CWR63_RS07110	COG0583	DNA-binding transcription factor activity
CWR63_RS07145	COG4691	Plasmid stability protein
CWR63_RS07175	COG2837	iron assimilation
CWR63_RS07195	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CWR63_RS07200	COG1335	isochorismatase
CWR63_RS07260	COG2346	COG2346, Truncated hemoglobins
CWR63_RS07270	COG1126	abc transporter atp-binding protein
CWR63_RS07275	COG0765	amino acid transport
CWR63_RS07280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWR63_RS07290	COG0789	Transcriptional regulator
CWR63_RS07300	COG0165	Argininosuccinate lyase
CWR63_RS07305	COG0668	transmembrane transport
CWR63_RS07355	COG0747	negative chemotaxis
CWR63_RS07360	COG0601	transmembrane transport
CWR63_RS07365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CWR63_RS07375	COG1280	lysine exporter protein (LysE YggA)
CWR63_RS07395	COG3161	chorismate lyase activity
CWR63_RS07400	COG1187	pseudouridine synthase activity
CWR63_RS07410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CWR63_RS07430	COG1999	signal sequence binding
CWR63_RS07435	COG0339	signal peptide processing
CWR63_RS07440	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CWR63_RS07445	COG4566	intracellular signal transduction
CWR63_RS07455	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CWR63_RS07460	COG0508	dehydrogenase complex catalyzes the overall conversion of
CWR63_RS07465	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CWR63_RS07470	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CWR63_RS07500	COG0745	RESPONSE REGULATOR receiver
CWR63_RS07505	COG2198	Histidine kinase
CWR63_RS07505	COG0643	Histidine kinase
CWR63_RS07515	COG0840	transmembrane signaling receptor activity
CWR63_RS07520	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CWR63_RS07530	COG0745	RESPONSE REGULATOR receiver
CWR63_RS07535	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CWR63_RS07570	COG1815	bacterial-type flagellum-dependent cell motility
CWR63_RS07575	COG1558	bacterial-type flagellum-dependent cell motility
CWR63_RS07585	COG1749	Flagellar hook protein flgE
CWR63_RS07615	COG1256	bacterial-type flagellum assembly
CWR63_RS07625	COG0840	transmembrane signaling receptor activity
CWR63_RS07645	COG1338	Plays a role in the flagellum-specific transport system
CWR63_RS07665	COG1580	Controls the rotational direction of flagella during chemotaxis
CWR63_RS07680	COG1157	protein secretion by the type III secretion system
CWR63_RS07685	COG1317	bacterial-type flagellum organization
CWR63_RS07690	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CWR63_RS07700	COG1677	Flagellar hook-basal body complex protein FliE
CWR63_RS07710	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CWR63_RS07740	COG0285	dihydrofolate synthase activity
CWR63_RS07775	COG0024	Methionine aminopeptidase
CWR63_RS07780	COG0052	Belongs to the universal ribosomal protein uS2 family
CWR63_RS07795	COG0233	cytoplasmic translational termination
CWR63_RS07800	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CWR63_RS07815	COG0750	zinc metalloprotease
CWR63_RS07820	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CWR63_RS07825	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CWR63_RS07850	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CWR63_RS07855	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CWR63_RS07880	COG0330	HflC and HflK could
CWR63_RS07895	COG2867	negative regulation of translational initiation
CWR63_RS07905	COG1960	acyl-CoA dehydrogenase activity
CWR63_RS07910	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CWR63_RS07935	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CWR63_RS07940	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CWR63_RS07945	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CWR63_RS07950	COG0084	hydrolase, TatD family'
CWR63_RS07975	COG1126	abc transporter atp-binding protein
CWR63_RS07985	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CWR63_RS07990	COG1012	belongs to the aldehyde dehydrogenase family
CWR63_RS08000	COG0028	Belongs to the TPP enzyme family
CWR63_RS08030	COG3189	MarR family transcriptional regulator
CWR63_RS08060	COG1595	DNA-templated transcription, initiation
CWR63_RS08070	COG0861	Integral membrane protein TerC family
CWR63_RS08095	COG2988	succinylglutamate desuccinylase activity
CWR63_RS08110	COG1253	flavin adenine dinucleotide binding
CWR63_RS08120	COG3181	Tripartite tricarboxylate transporter family receptor
CWR63_RS08125	COG2084	Dehydrogenase
CWR63_RS08160	COG2814	Major facilitator Superfamily
CWR63_RS08170	COG0583	DNA-binding transcription factor activity
CWR63_RS08200	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CWR63_RS08205	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CWR63_RS08210	COG0840	transmembrane signaling receptor activity
CWR63_RS08235	COG3468	outer membrane autotransporter barrel domain protein
CWR63_RS08240	COG3468	outer membrane autotransporter barrel domain protein
CWR63_RS08275	COG5265	(ABC) transporter
CWR63_RS08285	COG0667	Aldo Keto reductase
CWR63_RS08300	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CWR63_RS08340	COG1959	2 iron, 2 sulfur cluster binding
CWR63_RS08365	COG0400	carboxylic ester hydrolase activity
CWR63_RS08375	COG1566	PFAM secretion protein HlyD family protein
CWR63_RS08400	COG0235	Class ii aldolase
CWR63_RS08405	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CWR63_RS08410	COG0720	synthase
CWR63_RS08415	COG0602	queuosine metabolic process
CWR63_RS08435	COG4208	sulfate ABC transporter
CWR63_RS08445	COG0175	sulfate reduction
CWR63_RS08475	COG0335	large ribosomal subunit rRNA binding
CWR63_RS08485	COG0667	Aldo Keto reductase
CWR63_RS08490	COG1162	GTPase activity
CWR63_RS08495	COG0501	Belongs to the peptidase M48B family
CWR63_RS08500	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CWR63_RS08515	COG3396	Phenylacetate-CoA oxygenase
CWR63_RS08520	COG3460	Phenylacetate-CoA oxygenase
CWR63_RS08525	COG3396	Phenylacetate-CoA oxygenase
CWR63_RS08530	COG2151	metal-sulfur cluster biosynthetic enzyme
CWR63_RS08535	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CWR63_RS08540	COG1012	belongs to the aldehyde dehydrogenase family
CWR63_RS08545	COG1024	Enoyl-CoA hydratase
CWR63_RS08550	COG2050	protein possibly involved in aromatic compounds catabolism
CWR63_RS08565	COG3539	Fimbrial protein
CWR63_RS08570	COG3539	Fimbrial protein
CWR63_RS08575	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CWR63_RS08575	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CWR63_RS08585	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CWR63_RS08590	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CWR63_RS08605	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CWR63_RS08610	COG3842	ATPase activity
CWR63_RS08615	COG1176	ABC-type spermidine putrescine transport system, permease component I
CWR63_RS08620	COG1177	transmembrane transport
CWR63_RS08645	COG1960	acyl-CoA dehydrogenase activity
CWR63_RS08655	COG0704	Plays a role in the regulation of phosphate uptake
CWR63_RS08665	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CWR63_RS08670	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CWR63_RS08670	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CWR63_RS08675	COG1643	Atp-dependent helicase
CWR63_RS08690	COG0438	transferase activity, transferring glycosyl groups
CWR63_RS08695	COG0726	polysaccharide deacetylase
CWR63_RS08700	COG0463	Glycosyl transferase, family 2
CWR63_RS08705	COG0438	transferase activity, transferring glycosyl groups
CWR63_RS08710	COG2194	sulfuric ester hydrolase activity
CWR63_RS08735	COG0859	PFAM glycosyl transferase family 9
CWR63_RS08740	COG1132	(ABC) transporter
CWR63_RS08755	COG0077	Prephenate dehydratase
CWR63_RS08760	COG1530	ribonuclease E activity
CWR63_RS08800	COG1250	3-hydroxyacyl-CoA dehydrogenase
CWR63_RS08805	COG0154	amidase activity
CWR63_RS08835	COG2814	Major facilitator Superfamily
CWR63_RS08855	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CWR63_RS08860	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CWR63_RS08865	COG2814	Major facilitator Superfamily
CWR63_RS08870	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CWR63_RS08880	COG4176	ABC-type proline glycine betaine transport system permease component
CWR63_RS08890	COG1942	4-Oxalocrotonate Tautomerase
CWR63_RS08895	COG0183	Belongs to the thiolase family
CWR63_RS08905	COG1802	Transcriptional regulator
CWR63_RS08915	COG1024	Enoyl-CoA hydratase
CWR63_RS08920	COG0318	PFAM AMP-dependent synthetase and ligase
CWR63_RS08930	COG2032	superoxide dismutase activity
CWR63_RS08945	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CWR63_RS08970	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CWR63_RS08985	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CWR63_RS08990	COG0736	holo-[acyl-carrier-protein] synthase activity
CWR63_RS09005	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CWR63_RS09020	COG2224	Isocitrate lyase
CWR63_RS09030	COG1346	cytolysis
CWR63_RS09035	COG1380	Effector of murein hydrolase LrgA
CWR63_RS09040	COG4106	trans-aconitate 2-methyltransferase activity
CWR63_RS09040	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CWR63_RS09070	COG3278	Belongs to the heme-copper respiratory oxidase family
CWR63_RS09115	COG1131	(ABC) transporter
CWR63_RS09120	COG0842	Transport permease protein
CWR63_RS09125	COG0628	permease
CWR63_RS09140	COG2814	Major facilitator Superfamily
CWR63_RS09145	COG2841	Protein conserved in bacteria
CWR63_RS09170	COG0765	amino acid transport
CWR63_RS09175	COG0765	amino acid transport
CWR63_RS09180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWR63_RS09215	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CWR63_RS09220	COG1595	DNA-templated transcription, initiation
CWR63_RS09230	COG3530	Putative quorum-sensing-regulated virulence factor
CWR63_RS09235	COG0494	nUDIX hydrolase
CWR63_RS09250	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CWR63_RS09260	COG3468	outer membrane autotransporter barrel domain protein
CWR63_RS09275	COG5564	TIM-barrel signal transduction protein
CWR63_RS09290	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CWR63_RS09325	COG1131	(ABC) transporter
CWR63_RS09345	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CWR63_RS09345	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CWR63_RS09350	COG1562	ergosterol biosynthetic process
CWR63_RS09355	COG1562	ergosterol biosynthetic process
CWR63_RS09360	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CWR63_RS09380	COG2304	oxidoreductase activity
CWR63_RS09440	COG1047	Peptidyl-prolyl cis-trans
CWR63_RS09445	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CWR63_RS09450	COG0625	glutathione transferase activity
CWR63_RS09470	COG0523	cobalamin synthesis protein
CWR63_RS09480	COG0583	DNA-binding transcription factor activity
CWR63_RS09490	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CWR63_RS09495	COG1187	pseudouridine synthase activity
CWR63_RS09505	COG2251	uridine kinase activity
CWR63_RS09505	COG0195	Participates in both transcription termination and antitermination
CWR63_RS09540	COG1611	Belongs to the LOG family
CWR63_RS09555	COG0412	Dienelactone hydrolase
CWR63_RS09560	COG1283	sodium-dependent phosphate transmembrane transporter activity
CWR63_RS09565	COG1760	l-serine dehydratase
CWR63_RS09570	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CWR63_RS09585	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CWR63_RS09610	COG2311	Membrane
CWR63_RS09620	COG2358	TRAP transporter, solute receptor (TAXI family
CWR63_RS09625	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CWR63_RS09665	COG3395	kinase activity
CWR63_RS09670	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CWR63_RS09705	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CWR63_RS09745	COG4964	Belongs to the GSP D family
CWR63_RS09780	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CWR63_RS09790	COG1295	ribonuclease BN
CWR63_RS09805	COG0745	RESPONSE REGULATOR receiver
CWR63_RS09810	COG2205	protein histidine kinase activity
CWR63_RS09815	COG5001	Diguanylate cyclase
CWR63_RS09830	COG1763	Mo-molybdopterin cofactor biosynthetic process
CWR63_RS09835	COG0303	'Molybdopterin
CWR63_RS09840	COG0746	molybdenum cofactor guanylyltransferase activity
CWR63_RS09845	COG0489	protein tyrosine kinase activity
CWR63_RS09875	COG0243	molybdopterin cofactor binding
CWR63_RS09875	COG3383	formate dehydrogenase (NAD+) activity
CWR63_RS09880	COG0437	4 iron, 4 sulfur cluster binding
CWR63_RS09910	COG1122	ATPase activity
CWR63_RS09935	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CWR63_RS09950	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CWR63_RS10010	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CWR63_RS10020	COG2197	response regulator
CWR63_RS10025	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CWR63_RS10030	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CWR63_RS10045	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CWR63_RS10050	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CWR63_RS10060	COG1764	response to oxidative stress
CWR63_RS10065	COG2423	ornithine cyclodeaminase activity
CWR63_RS10075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWR63_RS10080	COG0765	amino acid transport
CWR63_RS10085	COG0765	amino acid transport
CWR63_RS10090	COG1126	abc transporter atp-binding protein
CWR63_RS10115	COG1522	sequence-specific DNA binding
CWR63_RS10125	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CWR63_RS10130	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CWR63_RS10140	COG0196	riboflavin kinase activity
CWR63_RS10145	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CWR63_RS10150	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CWR63_RS10150	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CWR63_RS10165	COG0210	DNA helicase
CWR63_RS10170	COG4771	TonB-dependent receptor
CWR63_RS10175	COG0488	(ABC) transporter
CWR63_RS10180	COG2890	protein-(glutamine-N5) methyltransferase activity
CWR63_RS10195	COG0436	Aminotransferase
CWR63_RS10225	COG1278	Cold shock
CWR63_RS10235	COG1278	Cold shock
CWR63_RS10250	COG0740	serine-type endopeptidase activity
CWR63_RS10260	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CWR63_RS10265	COG0583	DNA-binding transcription factor activity
CWR63_RS10270	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR63_RS10285	COG1024	Enoyl-CoA hydratase
CWR63_RS10300	COG1028	Short-chain dehydrogenase reductase Sdr
CWR63_RS10305	COG1960	acyl-CoA dehydrogenase activity
CWR63_RS10320	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CWR63_RS10330	COG3468	outer membrane autotransporter barrel domain protein
CWR63_RS10350	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CWR63_RS10360	COG1104	cysteine desulfurase activity
CWR63_RS10365	COG0822	iron-sulfur transferase activity
CWR63_RS10370	COG0316	Belongs to the HesB IscA family
CWR63_RS10385	COG0633	Ferredoxin
CWR63_RS10400	COG1024	Enoyl-CoA hydratase
CWR63_RS10430	COG1022	Amp-dependent synthetase and ligase
CWR63_RS10450	COG1028	Short-chain dehydrogenase reductase Sdr
CWR63_RS10460	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CWR63_RS10475	COG1136	(ABC) transporter
CWR63_RS10480	COG0084	hydrolase, TatD family'
CWR63_RS10495	COG4221	oxidoreductase activity
CWR63_RS10500	COG0406	alpha-ribazole phosphatase activity
CWR63_RS10510	COG3842	ATPase activity
CWR63_RS10525	COG2233	PERMEase
CWR63_RS10530	COG0840	transmembrane signaling receptor activity
CWR63_RS10535	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CWR63_RS10545	COG1534	Rna-binding protein
CWR63_RS10555	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CWR63_RS10575	COG0248	Ppx GppA phosphatase
CWR63_RS10675	COG0559	Belongs to the binding-protein-dependent transport system permease family
CWR63_RS10705	COG0559	Belongs to the binding-protein-dependent transport system permease family
CWR63_RS10740	COG2072	flavoprotein involved in K transport
CWR63_RS10745	COG1250	3-hydroxyacyl-CoA dehydrogenase
CWR63_RS10775	COG1137	ATPase activity
CWR63_RS10785	COG0154	amidase activity
CWR63_RS10790	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CWR63_RS10810	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CWR63_RS10815	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CWR63_RS10820	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CWR63_RS10830	COG0179	Fumarylacetoacetate (FAA) hydrolase
CWR63_RS10840	COG1522	sequence-specific DNA binding
CWR63_RS10845	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CWR63_RS10850	COG1473	amidohydrolase
CWR63_RS10855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWR63_RS10860	COG4597	amino acid ABC transporter
CWR63_RS10865	COG0765	amino acid transport
CWR63_RS10870	COG1126	abc transporter atp-binding protein
CWR63_RS10885	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CWR63_RS10915	COG3181	Tripartite tricarboxylate transporter family receptor
CWR63_RS10935	COG0583	DNA-binding transcription factor activity
CWR63_RS10970	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CWR63_RS11010	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CWR63_RS11020	COG1132	(ABC) transporter
CWR63_RS11045	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CWR63_RS11055	COG1012	belongs to the aldehyde dehydrogenase family
CWR63_RS11065	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CWR63_RS11075	COG0511	ligase activity, forming carbon-carbon bonds
CWR63_RS11100	COG2188	Transcriptional regulator
CWR63_RS11105	COG0439	Biotin carboxylase
CWR63_RS11115	COG0511	ligase activity, forming carbon-carbon bonds
CWR63_RS11130	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CWR63_RS11160	COG3971	2-oxopent-4-enoate hydratase activity
CWR63_RS11165	COG0583	DNA-binding transcription factor activity
CWR63_RS11180	COG0179	Fumarylacetoacetate (FAA) hydrolase
CWR63_RS11230	COG1028	Short-chain dehydrogenase reductase Sdr
CWR63_RS11270	COG0251	oxidation-reduction process
CWR63_RS11370	COG4669	(LipO)protein
CWR63_RS11405	COG4790	Type iii secretion
CWR63_RS11410	COG4794	Type iii secretion
CWR63_RS11415	COG4791	protein targeting
CWR63_RS11420	COG4792	protein secretion
CWR63_RS11455	COG2208	phosphoserine phosphatase activity
CWR63_RS11455	COG2770	Histidine kinase
CWR63_RS11465	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CWR63_RS11470	COG2172	sigma factor antagonist activity
CWR63_RS11475	COG1366	Belongs to the anti-sigma-factor antagonist family
CWR63_RS11480	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CWR63_RS11520	COG2321	neutral zinc metallopeptidase
CWR63_RS11525	COG0009	L-threonylcarbamoyladenylate synthase
CWR63_RS11530	COG1994	Peptidase M50
CWR63_RS11535	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CWR63_RS11540	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CWR63_RS11545	COG3539	Fimbrial protein
CWR63_RS11555	COG2850	peptidyl-arginine hydroxylation
CWR63_RS11565	COG3360	Dodecin
CWR63_RS11600	COG0668	transmembrane transport
CWR63_RS11620	COG0483	inositol monophosphate 1-phosphatase activity
CWR63_RS11625	COG1253	flavin adenine dinucleotide binding
CWR63_RS11645	COG3063	Type IV pilus biogenesis stability protein PilW
CWR63_RS11660	COG0825	malonyl-CoA metabolic process
CWR63_RS11670	COG0527	aspartate kinase activity
CWR63_RS11695	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CWR63_RS11695	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CWR63_RS11710	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CWR63_RS11720	COG1028	Short-chain dehydrogenase reductase Sdr
CWR63_RS11730	COG0583	DNA-binding transcription factor activity
CWR63_RS11755	COG3842	ATPase activity
CWR63_RS11765	COG0446	pyridine nucleotide-disulphide oxidoreductase
CWR63_RS11765	COG1902	pentaerythritol trinitrate reductase activity
CWR63_RS11770	COG1414	Transcriptional regulator
CWR63_RS11775	COG1832	CoA-binding protein
CWR63_RS11785	COG0251	oxidation-reduction process
CWR63_RS11810	COG1902	pentaerythritol trinitrate reductase activity
CWR63_RS11820	COG1215	transferase activity, transferring glycosyl groups
CWR63_RS11825	COG1649	PFAM Uncharacterised BCR, COG1649
CWR63_RS11825	COG0726	polysaccharide deacetylase
CWR63_RS11845	COG1846	Transcriptional regulator
CWR63_RS11875	COG2080	2 iron, 2 sulfur cluster binding
CWR63_RS11880	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CWR63_RS11890	COG0596	Alpha beta hydrolase
CWR63_RS11895	COG2309	aminopeptidase activity
CWR63_RS11900	COG1335	isochorismatase
CWR63_RS11905	COG2010	Cytochrome c
CWR63_RS11905	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CWR63_RS11910	COG1017	nitric oxide dioxygenase activity
CWR63_RS11910	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CWR63_RS11925	COG3181	Tripartite tricarboxylate transporter family receptor
CWR63_RS11935	COG0318	PFAM AMP-dependent synthetase and ligase
CWR63_RS11945	COG0183	Belongs to the thiolase family
CWR63_RS11950	COG1250	3-hydroxyacyl-CoA dehydrogenase
CWR63_RS11950	COG1024	Enoyl-CoA hydratase
CWR63_RS11965	COG0183	Belongs to the thiolase family
CWR63_RS11980	COG2197	response regulator
CWR63_RS11995	COG0166	Belongs to the GPI family
CWR63_RS12000	COG1045	serine acetyltransferase
CWR63_RS12025	COG0483	inositol monophosphate 1-phosphatase activity
CWR63_RS12035	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CWR63_RS12055	COG0598	Magnesium transport protein CorA
CWR63_RS12065	COG0747	negative chemotaxis
CWR63_RS12070	COG0601	transmembrane transport
CWR63_RS12075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CWR63_RS12080	COG4172	Belongs to the ABC transporter superfamily
CWR63_RS12130	COG4964	Belongs to the GSP D family
CWR63_RS12195	COG3474	cytochrome
CWR63_RS12200	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CWR63_RS12215	COG3384	dioxygenase
CWR63_RS12220	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CWR63_RS12240	COG2885	chlorophyll binding
CWR63_RS12275	COG0697	spore germination
CWR63_RS12280	COG0730	response to heat
CWR63_RS12295	COG3264	Mechanosensitive ion channel
CWR63_RS12295	COG1511	domain protein
CWR63_RS12300	COG0583	DNA-binding transcription factor activity
CWR63_RS12305	COG0427	acetyl-CoA hydrolase
CWR63_RS12310	COG0385	Bile acid
CWR63_RS12350	COG3468	outer membrane autotransporter barrel domain protein
CWR63_RS12365	COG0799	negative regulation of ribosome biogenesis
CWR63_RS12380	COG0151	Belongs to the GarS family
CWR63_RS12390	COG0433	COG0433 Predicted ATPase
CWR63_RS12395	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CWR63_RS12405	COG1012	belongs to the aldehyde dehydrogenase family
CWR63_RS12430	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CWR63_RS12440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CWR63_RS12450	COG0747	negative chemotaxis
CWR63_RS12460	COG0473	3-isopropylmalate dehydrogenase activity
CWR63_RS12480	COG1846	Transcriptional regulator
CWR63_RS12490	COG0697	spore germination
CWR63_RS12500	COG0501	Belongs to the peptidase M48B family
CWR63_RS12520	COG0583	DNA-binding transcription factor activity
CWR63_RS12525	COG3842	ATPase activity
CWR63_RS12530	COG1178	ABC-type Fe3 transport system permease component
CWR63_RS12535	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CWR63_RS12540	COG1840	ABC-type Fe3 transport system, periplasmic component
CWR63_RS12575	COG3181	Tripartite tricarboxylate transporter family receptor
CWR63_RS12585	COG1722	exodeoxyribonuclease VII activity
CWR63_RS12590	COG0142	geranyltranstransferase activity
CWR63_RS12600	COG1469	GTP cyclohydrolase I activity
CWR63_RS12605	COG0360	Binds together with S18 to 16S ribosomal RNA
CWR63_RS12610	COG2965	DNA replication, synthesis of RNA primer
CWR63_RS12615	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CWR63_RS12635	COG0305	Participates in initiation and elongation during chromosome replication
CWR63_RS12645	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CWR63_RS12650	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CWR63_RS12655	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CWR63_RS12660	COG3737	Protein of unknown function (DUF498/DUF598)
CWR63_RS12665	COG0436	Aminotransferase
CWR63_RS12685	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CWR63_RS12690	COG0308	aminopeptidase N
CWR63_RS12710	COG0312	modulator of DNA gyrase
CWR63_RS12715	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CWR63_RS12720	COG3064	Membrane
CWR63_RS12720	COG3210	domain, Protein
CWR63_RS12720	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CWR63_RS12720	COG3064	Membrane
CWR63_RS12720	COG3210	domain, Protein
CWR63_RS12720	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CWR63_RS12725	COG0277	FAD linked oxidase domain protein
CWR63_RS12730	COG0277	FAD linked oxidase domain protein
CWR63_RS12740	COG0247	lactate metabolic process
CWR63_RS12745	COG2819	hydrolase of the alpha beta superfamily
CWR63_RS12785	COG0583	DNA-binding transcription factor activity
CWR63_RS12795	COG0730	response to heat
CWR63_RS12800	COG0625	glutathione transferase activity
CWR63_RS12805	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CWR63_RS12810	COG3909	cytochrome
CWR63_RS12845	COG3706	GGDEF domain
CWR63_RS12885	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
CWR63_RS12895	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CWR63_RS12900	COG0069	glutamate synthase activity
CWR63_RS12905	COG2391	methyltransferase activity
CWR63_RS12910	COG0679	Auxin Efflux Carrier
CWR63_RS12935	COG0557	exoribonuclease II activity
CWR63_RS12940	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CWR63_RS12950	COG3128	pkhd-type hydroxylase
CWR63_RS12955	COG0776	regulation of translation
CWR63_RS12985	COG0642	Histidine kinase
CWR63_RS12990	COG3158	transport of potassium into the cell
CWR63_RS13000	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CWR63_RS13015	COG0583	DNA-binding transcription factor activity
CWR63_RS13025	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CWR63_RS13045	COG2186	Transcriptional regulator
CWR63_RS13050	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CWR63_RS13070	COG0268	Binds directly to 16S ribosomal RNA
CWR63_RS13080	COG0728	peptidoglycan biosynthetic process
CWR63_RS13100	COG2835	tetraacyldisaccharide 4'-kinase activity
CWR63_RS13110	COG0848	biopolymer transport protein
CWR63_RS13115	COG0811	peptide transport
CWR63_RS13125	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CWR63_RS13130	COG0038	chloride channel
CWR63_RS13135	COG0183	Belongs to the thiolase family
CWR63_RS13145	COG1278	Cold shock
CWR63_RS13160	COG4953	penicillin-binding protein 1C
CWR63_RS13165	COG0542	response to heat
CWR63_RS13170	COG2995	paraquat-inducible protein a
CWR63_RS13175	COG3008	intermembrane lipid transfer
CWR63_RS13175	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CWR63_RS13185	COG0506	proline dehydrogenase activity
CWR63_RS13185	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CWR63_RS13185	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CWR63_RS13220	COG1309	transcriptional regulator
CWR63_RS13235	COG0004	ammonium transporteR
CWR63_RS13260	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CWR63_RS13265	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CWR63_RS13305	COG0500	methyltransferase
CWR63_RS13320	COG2367	Beta-lactamase
CWR63_RS13330	COG1522	sequence-specific DNA binding
CWR63_RS13345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CWR63_RS13380	COG0540	Belongs to the ATCase OTCase family
CWR63_RS13395	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR63_RS13400	COG0583	DNA-binding transcription factor activity
CWR63_RS13405	COG0183	Belongs to the thiolase family
CWR63_RS13420	COG1028	Short-chain dehydrogenase reductase Sdr
CWR63_RS13435	COG3842	ATPase activity
CWR63_RS13440	COG1024	Enoyl-CoA hydratase
CWR63_RS13440	COG1250	3-hydroxyacyl-CoA dehydrogenase
CWR63_RS13460	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CWR63_RS13465	COG2137	regulation of response to DNA damage stimulus
CWR63_RS13485	COG0045	succinate-CoA ligase (ADP-forming) activity
CWR63_RS13490	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CWR63_RS13495	COG0861	Integral membrane protein TerC family
CWR63_RS13500	COG0861	Integral membrane protein TerC family
CWR63_RS13545	COG2204	response regulator
CWR63_RS13550	COG2204	response regulator
CWR63_RS13555	COG0028	Belongs to the TPP enzyme family
CWR63_RS13610	COG1028	Short-chain dehydrogenase reductase Sdr
CWR63_RS13620	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CWR63_RS13625	COG4575	ribosome binding
CWR63_RS13645	COG1058	Belongs to the CinA family
CWR63_RS13645	COG1546	Belongs to the CinA family
CWR63_RS13660	COG0392	lysyltransferase activity
CWR63_RS13670	COG3568	Endonuclease Exonuclease Phosphatase
CWR63_RS13680	COG1695	Transcriptional regulator
CWR63_RS13700	COG0583	DNA-binding transcription factor activity
CWR63_RS13730	COG3181	Tripartite tricarboxylate transporter family receptor
CWR63_RS13735	COG4948	Mandelate Racemase Muconate Lactonizing
CWR63_RS13765	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CWR63_RS13800	COG3005	denitrification pathway
CWR63_RS13805	COG3043	anaerobic respiration
CWR63_RS13825	COG0330	HflC and HflK could
CWR63_RS13850	COG0583	DNA-binding transcription factor activity
CWR63_RS13855	COG1028	Short-chain dehydrogenase reductase Sdr
CWR63_RS13885	COG0431	NADPH-dependent FMN reductase
CWR63_RS13910	COG0824	Thioesterase
CWR63_RS13915	COG1454	alcohol dehydrogenase
CWR63_RS13925	COG1250	3-hydroxyacyl-CoA dehydrogenase
CWR63_RS13925	COG1024	Enoyl-CoA hydratase
CWR63_RS13930	COG3181	Tripartite tricarboxylate transporter family receptor
CWR63_RS13940	COG1024	Enoyl-CoA hydratase
CWR63_RS13950	COG3181	Tripartite tricarboxylate transporter family receptor
CWR63_RS13955	COG0583	DNA-binding transcription factor activity
CWR63_RS13960	COG1028	Short-chain dehydrogenase reductase Sdr
CWR63_RS13975	COG0183	Belongs to the thiolase family
CWR63_RS13980	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR63_RS13995	COG3119	arylsulfatase activity
CWR63_RS14010	COG0625	glutathione transferase activity
CWR63_RS14015	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
CWR63_RS14020	COG2944	sequence-specific DNA binding
CWR63_RS14030	COG2197	response regulator
CWR63_RS14050	COG3119	arylsulfatase activity
CWR63_RS14090	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CWR63_RS14105	COG1028	Short-chain dehydrogenase reductase Sdr
CWR63_RS14110	COG0861	Integral membrane protein TerC family
CWR63_RS14135	COG2267	carboxylic ester hydrolase activity
CWR63_RS14140	COG1228	amidohydrolase
CWR63_RS14150	COG0179	Fumarylacetoacetate (FAA) hydrolase
CWR63_RS14160	COG1172	Belongs to the binding-protein-dependent transport system permease family
CWR63_RS14180	COG0583	DNA-binding transcription factor activity
CWR63_RS14185	COG3181	Tripartite tricarboxylate transporter family receptor
CWR63_RS14210	COG2188	Transcriptional regulator
CWR63_RS14220	COG1028	Short-chain dehydrogenase reductase Sdr
CWR63_RS14225	COG1414	Transcriptional regulator
CWR63_RS14240	COG1176	ABC-type spermidine putrescine transport system, permease component I
CWR63_RS14245	COG0395	ABC-type sugar transport system, permease component
CWR63_RS14260	COG0439	Biotin carboxylase
CWR63_RS14265	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CWR63_RS14270	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR63_RS14290	COG0833	amino acid
CWR63_RS14320	COG3829	transcription factor binding
CWR63_RS14330	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CWR63_RS14350	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR63_RS14355	COG1012	belongs to the aldehyde dehydrogenase family
CWR63_RS14375	COG0583	DNA-binding transcription factor activity
CWR63_RS14380	COG4692	amylo-alpha-1,6-glucosidase activity
CWR63_RS14390	COG0183	Belongs to the thiolase family
CWR63_RS14405	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR63_RS14410	COG0633	Ferredoxin
CWR63_RS14420	COG1024	Enoyl-CoA hydratase
CWR63_RS14430	COG4638	Rieske (2fe-2S)
CWR63_RS14435	COG0683	leucine binding
CWR63_RS14440	COG0559	Belongs to the binding-protein-dependent transport system permease family
CWR63_RS14500	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CWR63_RS14510	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CWR63_RS14515	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CWR63_RS14530	COG0330	HflC and HflK could
CWR63_RS14535	COG0330	HflC and HflK could
CWR63_RS14540	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CWR63_RS14545	COG1923	regulation of RNA biosynthetic process
CWR63_RS14555	COG1160	GTP binding
CWR63_RS14560	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CWR63_RS14565	COG2976	Protein conserved in bacteria
CWR63_RS14590	COG0105	UTP biosynthetic process
CWR63_RS14610	COG0642	Histidine kinase
CWR63_RS14620	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CWR63_RS14645	COG0425	Belongs to the sulfur carrier protein TusA family
CWR63_RS14700	COG4172	Belongs to the ABC transporter superfamily
CWR63_RS14705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CWR63_RS14710	COG0601	transmembrane transport
CWR63_RS14715	COG0747	negative chemotaxis
CWR63_RS14740	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CWR63_RS14790	COG1640	4-alpha-glucanotransferase
CWR63_RS14835	COG0667	Aldo Keto reductase
CWR63_RS14850	COG2259	Doxx family
CWR63_RS14890	COG0386	Belongs to the glutathione peroxidase family
CWR63_RS14895	COG0625	glutathione transferase activity
CWR63_RS14910	COG0095	Lipoate-protein ligase
CWR63_RS14925	COG0688	phosphatidylethanolamine metabolic process
CWR63_RS14935	COG1464	Belongs to the NlpA lipoprotein family
CWR63_RS14950	COG2363	Small membrane protein
CWR63_RS14975	COG2133	pyrroloquinoline quinone binding
CWR63_RS14980	COG0625	glutathione transferase activity
CWR63_RS14985	COG1794	racemase activity, acting on amino acids and derivatives
CWR63_RS15005	COG0559	Belongs to the binding-protein-dependent transport system permease family
CWR63_RS15015	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CWR63_RS15025	COG1653	transport
CWR63_RS15030	COG1175	transmembrane transport
CWR63_RS15035	COG0395	ABC-type sugar transport system, permease component
CWR63_RS15055	COG3321	synthase
CWR63_RS15055	COG1028	Short-chain dehydrogenase reductase Sdr
CWR63_RS15055	COG0604	alcohol dehydrogenase
CWR63_RS15070	COG0300	oxidoreductase activity
CWR63_RS15090	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CWR63_RS15105	COG0438	transferase activity, transferring glycosyl groups
CWR63_RS15125	COG0463	Glycosyl transferase, family 2
CWR63_RS15140	COG0783	Belongs to the Dps family
CWR63_RS15155	COG0583	DNA-binding transcription factor activity
CWR63_RS15160	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CWR63_RS15175	COG0656	L-ascorbic acid biosynthetic process
CWR63_RS15180	COG2814	Major facilitator Superfamily
CWR63_RS15185	COG0583	DNA-binding transcription factor activity
CWR63_RS15195	COG1840	ABC-type Fe3 transport system, periplasmic component
CWR63_RS15205	COG3842	ATPase activity
CWR63_RS15210	COG1741	Belongs to the pirin family
CWR63_RS15215	COG1741	Belongs to the pirin family
CWR63_RS15220	COG0583	DNA-binding transcription factor activity
CWR63_RS15225	COG2204	response regulator
CWR63_RS15235	COG0174	glutamine synthetase
CWR63_RS15240	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CWR63_RS15250	COG5002	protein histidine kinase activity
CWR63_RS15250	COG5001	Diguanylate cyclase
CWR63_RS15295	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CWR63_RS15300	COG0791	NLP P60 protein
CWR63_RS15305	COG1028	Short-chain dehydrogenase reductase Sdr
CWR63_RS15310	COG2863	cytochrome
CWR63_RS15315	COG3258	Cytochrome c
CWR63_RS15320	COG0194	GDP metabolic process
CWR63_RS15325	COG1758	RNA polymerase activity
CWR63_RS15330	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CWR63_RS15335	COG1126	abc transporter atp-binding protein
CWR63_RS15340	COG0765	amino acid transport
CWR63_RS15345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWR63_RS15365	COG0583	DNA-binding transcription factor activity
CWR63_RS15390	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CWR63_RS15405	COG2831	hemolysin activation secretion protein
CWR63_RS15410	COG3539	Fimbrial protein
CWR63_RS15415	COG3188	usher protein
CWR63_RS15420	COG3121	Chaperone
CWR63_RS15430	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CWR63_RS15430	COG3210	domain, Protein
CWR63_RS15430	COG3064	Membrane
CWR63_RS15435	COG2197	response regulator
CWR63_RS15490	COG4181	ATPase activity
CWR63_RS15500	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CWR63_RS15505	COG0584	glycerophosphoryl diester phosphodiesterase
CWR63_RS15510	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CWR63_RS15520	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CWR63_RS15520	COG0678	peroxiredoxin activity
CWR63_RS15530	COG0789	Transcriptional regulator
CWR63_RS15570	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CWR63_RS15580	COG2252	PERMEase
CWR63_RS15585	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CWR63_RS15590	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CWR63_RS15620	COG0488	(ABC) transporter
CWR63_RS15625	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CWR63_RS15635	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CWR63_RS15640	COG1024	Enoyl-CoA hydratase
CWR63_RS15645	COG1619	proteins homologs of microcin C7 resistance protein MccF
CWR63_RS15650	COG0590	tRNA wobble adenosine to inosine editing
CWR63_RS15670	COG2212	antiporter activity
CWR63_RS15675	COG1863	multisubunit Na H antiporter MnhE subunit
CWR63_RS15680	COG0651	ATP synthesis coupled electron transport
CWR63_RS15685	COG1006	Multisubunit Na H antiporter MnhC subunit
CWR63_RS15690	COG2111	Na H antiporter
CWR63_RS15690	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CWR63_RS15705	COG0420	3'-5' exonuclease activity
CWR63_RS15740	COG0395	ABC-type sugar transport system, permease component
CWR63_RS15750	COG3842	ATPase activity
CWR63_RS15780	COG3181	Tripartite tricarboxylate transporter family receptor
CWR63_RS15785	COG3976	FMN-binding domain protein
CWR63_RS15785	COG1053	succinate dehydrogenase
CWR63_RS15815	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CWR63_RS15845	COG0450	alkyl hydroperoxide reductase
CWR63_RS15850	COG1960	acyl-CoA dehydrogenase activity
CWR63_RS15865	COG0123	including yeast histone deacetylase and acetoin utilization protein
CWR63_RS15870	COG2951	lytic endotransglycosylase activity
CWR63_RS15890	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CWR63_RS15895	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CWR63_RS15925	COG0287	Prephenate dehydrogenase
CWR63_RS15960	COG2814	Major facilitator Superfamily
CWR63_RS16030	COG0583	DNA-binding transcription factor activity
CWR63_RS16045	COG0179	Fumarylacetoacetate (FAA) hydrolase
CWR63_RS16070	COG1053	succinate dehydrogenase
CWR63_RS16075	COG1012	belongs to the aldehyde dehydrogenase family
CWR63_RS16080	COG2079	MmgE PrpD family protein
CWR63_RS16090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CWR63_RS16115	COG0028	Belongs to the TPP enzyme family
CWR63_RS16115	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
CWR63_RS16120	COG0436	Aminotransferase
CWR63_RS16140	COG0778	Nitroreductase
CWR63_RS16145	COG2814	Major facilitator Superfamily
CWR63_RS16150	COG3706	GGDEF domain
CWR63_RS16155	COG0589	response to stress
CWR63_RS16165	COG2951	lytic endotransglycosylase activity
CWR63_RS16170	COG2833	Protein of unknown function (DUF455)
CWR63_RS16185	COG1132	(ABC) transporter
CWR63_RS16195	COG1181	Belongs to the D-alanine--D-alanine ligase family
CWR63_RS16195	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CWR63_RS16200	COG3237	CsbD-like
CWR63_RS16210	COG2823	Periplasmic or secreted lipoprotein
CWR63_RS16230	COG0672	)-iron permease
CWR63_RS16245	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
CWR63_RS16250	COG1028	Short-chain dehydrogenase reductase Sdr
CWR63_RS16255	COG3243	poly(R)-hydroxyalkanoic acid synthase
CWR63_RS16265	COG0564	pseudouridine synthase activity
CWR63_RS16275	COG1199	ATP-dependent helicase activity
CWR63_RS16280	COG2183	response to ionizing radiation
CWR63_RS16305	COG4774	siderophore transport
CWR63_RS16315	COG1595	DNA-templated transcription, initiation
CWR63_RS16320	COG2175	clavaminate synthase activity
CWR63_RS16330	COG3181	Tripartite tricarboxylate transporter family receptor
CWR63_RS16335	COG0583	DNA-binding transcription factor activity
CWR63_RS16340	COG1028	Short-chain dehydrogenase reductase Sdr
CWR63_RS16345	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CWR63_RS16350	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CWR63_RS16355	COG0508	dehydrogenase complex catalyzes the overall conversion of
CWR63_RS16360	COG0567	Dehydrogenase, E1 component
CWR63_RS16370	COG1522	sequence-specific DNA binding
CWR63_RS16380	COG0281	malic enzyme
CWR63_RS16380	COG0280	phosphate acetyltransferase
CWR63_RS16385	COG3539	Fimbrial protein
CWR63_RS16400	COG0372	Belongs to the citrate synthase family
CWR63_RS16405	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CWR63_RS16410	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CWR63_RS16415	COG1053	succinate dehydrogenase
CWR63_RS16420	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CWR63_RS16425	COG2009	succinate dehydrogenase
CWR63_RS16430	COG2188	Transcriptional regulator
CWR63_RS16435	COG0039	L-malate dehydrogenase activity
CWR63_RS16455	COG2828	Protein conserved in bacteria
CWR63_RS16465	COG1981	membrane
CWR63_RS16490	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CWR63_RS16500	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CWR63_RS16535	COG0148	phosphopyruvate hydratase activity
CWR63_RS16545	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CWR63_RS16550	COG0504	CTP synthase activity
CWR63_RS16570	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CWR63_RS16580	COG0747	negative chemotaxis
CWR63_RS16585	COG4172	Belongs to the ABC transporter superfamily
CWR63_RS16590	COG1446	asparaginase
CWR63_RS16620	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CWR63_RS16635	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CWR63_RS16640	COG0697	spore germination
CWR63_RS16645	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CWR63_RS16655	COG3193	protein, possibly involved in utilization of glycolate and propanediol
CWR63_RS16660	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CWR63_RS16665	COG0791	NLP P60 protein
CWR63_RS16675	COG0583	DNA-binding transcription factor activity
CWR63_RS16690	COG0583	DNA-binding transcription factor activity
CWR63_RS16715	COG0670	Belongs to the BI1 family
CWR63_RS16720	COG3181	Tripartite tricarboxylate transporter family receptor
CWR63_RS16730	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CWR63_RS16740	COG1381	Involved in DNA repair and RecF pathway recombination
CWR63_RS16745	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CWR63_RS16750	COG0571	ribonuclease III activity
CWR63_RS16755	COG0681	Belongs to the peptidase S26 family
CWR63_RS16765	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CWR63_RS16790	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CWR63_RS16795	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CWR63_RS16820	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CWR63_RS16825	COG1399	metal-binding, possibly nucleic acid-binding protein
CWR63_RS16840	COG3023	N-Acetylmuramoyl-L-alanine amidase
CWR63_RS16850	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CWR63_RS16855	COG0546	phosphoglycolate phosphatase activity
CWR63_RS16865	COG1530	ribonuclease E activity
CWR63_RS16875	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CWR63_RS16880	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CWR63_RS16905	COG3228	Belongs to the MtfA family
CWR63_RS16915	COG0251	oxidation-reduction process
CWR63_RS16925	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CWR63_RS16940	COG2878	Part of a membrane complex involved in electron transport
CWR63_RS16945	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CWR63_RS16980	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CWR63_RS17005	COG1268	BioY protein
CWR63_RS17010	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CWR63_RS17015	COG1122	ATPase activity
CWR63_RS17020	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CWR63_RS17030	COG0271	Belongs to the BolA IbaG family
CWR63_RS17035	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CWR63_RS17050	COG1196	nuclear chromosome segregation
CWR63_RS17055	COG0477	Major facilitator Superfamily
CWR63_RS17060	COG1573	uracil-dna glycosylase
CWR63_RS17065	COG1214	PFAM Peptidase M22, glycoprotease
CWR63_RS17080	COG0450	alkyl hydroperoxide reductase
CWR63_RS17085	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CWR63_RS17100	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CWR63_RS17110	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CWR63_RS17115	COG0560	Phosphoserine phosphatase
CWR63_RS17120	COG0583	DNA-binding transcription factor activity
CWR63_RS17125	COG3181	Tripartite tricarboxylate transporter family receptor
CWR63_RS17130	COG0028	Belongs to the TPP enzyme family
CWR63_RS17155	COG4774	siderophore transport
CWR63_RS17165	COG1007	ATP synthesis coupled electron transport
CWR63_RS17180	COG0713	ATP synthesis coupled electron transport
CWR63_RS17190	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CWR63_RS17195	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CWR63_RS17200	COG1034	ATP synthesis coupled electron transport
CWR63_RS17210	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CWR63_RS17225	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CWR63_RS17230	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CWR63_RS17235	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CWR63_RS17255	COG0671	phosphoesterase, PA-phosphatase related
CWR63_RS17265	COG1597	lipid kinase activity
CWR63_RS17270	COG0583	DNA-binding transcription factor activity
CWR63_RS17275	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CWR63_RS17280	COG1733	regulation of RNA biosynthetic process
CWR63_RS17285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CWR63_RS17305	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
CWR63_RS17325	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CWR63_RS17345	COG3608	succinylglutamate desuccinylase aspartoacylase
CWR63_RS17350	COG0626	cystathionine gamma-synthase activity
CWR63_RS17355	COG0583	DNA-binding transcription factor activity
CWR63_RS17365	COG3181	Tripartite tricarboxylate transporter family receptor
CWR63_RS17370	COG0165	Argininosuccinate lyase
CWR63_RS17385	COG3799	methylaspartate ammonia-lyase activity
CWR63_RS17395	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CWR63_RS17405	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CWR63_RS17410	COG0149	triose-phosphate isomerase activity
CWR63_RS17430	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CWR63_RS17440	COG1185	polyribonucleotide nucleotidyltransferase activity
CWR63_RS17445	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CWR63_RS17460	COG1183	phosphatidylcholine synthase activity
CWR63_RS17470	COG0440	acetolactate synthase activity
CWR63_RS17475	COG0028	Belongs to the TPP enzyme family
CWR63_RS17480	COG1289	transmembrane transporter activity
CWR63_RS17490	COG3022	response to hydroperoxide
CWR63_RS17495	COG1028	Short-chain dehydrogenase reductase Sdr
CWR63_RS17510	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CWR63_RS17540	COG2814	Major facilitator Superfamily
CWR63_RS17560	COG3706	GGDEF domain
CWR63_RS17595	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CWR63_RS17605	COG1674	ftsk spoiiie
CWR63_RS17610	COG0492	ferredoxin-NADP+ reductase activity
CWR63_RS17615	COG1193	negative regulation of DNA recombination
CWR63_RS17625	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CWR63_RS17645	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CWR63_RS17650	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CWR63_RS17655	COG2205	protein histidine kinase activity
CWR63_RS17660	COG0745	RESPONSE REGULATOR receiver
CWR63_RS17695	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CWR63_RS17715	COG0612	Peptidase, M16
CWR63_RS17735	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CWR63_RS17750	COG1420	regulation of RNA biosynthetic process
CWR63_RS17760	COG0497	DNA recombination
CWR63_RS17770	COG0735	belongs to the Fur family
CWR63_RS17775	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CWR63_RS17820	COG0446	pyridine nucleotide-disulphide oxidoreductase
CWR63_RS17820	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CWR63_RS17825	COG4311	Sarcosine oxidase, delta subunit
CWR63_RS17830	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CWR63_RS17840	COG0583	DNA-binding transcription factor activity
CWR63_RS17860	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR63_RS17865	COG2030	dehydratase
CWR63_RS17875	COG1024	Enoyl-CoA hydratase
CWR63_RS17900	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CWR63_RS17910	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CWR63_RS17910	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CWR63_RS17925	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CWR63_RS17940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CWR63_RS17950	COG0405	Gamma-glutamyltransferase
CWR63_RS17965	COG1280	lysine exporter protein (LysE YggA)
CWR63_RS17995	COG0583	DNA-binding transcription factor activity
CWR63_RS18035	COG1414	Transcriptional regulator
CWR63_RS18040	COG1058	Belongs to the CinA family
CWR63_RS18040	COG1546	Belongs to the CinA family
CWR63_RS18055	COG0513	Belongs to the DEAD box helicase family
CWR63_RS18085	COG0429	hydrolase of the alpha beta-hydrolase fold
CWR63_RS18090	COG4783	chaperone-mediated protein folding
CWR63_RS18105	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CWR63_RS18120	COG0006	proline dipeptidase activity
CWR63_RS18130	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CWR63_RS18175	COG0514	ATP-dependent DNA helicase (RecQ)
CWR63_RS18200	COG1271	oxidase subunit
CWR63_RS18215	COG2894	cell division
CWR63_RS18220	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CWR63_RS18235	COG0488	(ABC) transporter
CWR63_RS18260	COG4608	Belongs to the ABC transporter superfamily
CWR63_RS18265	COG0444	Belongs to the ABC transporter superfamily
CWR63_RS18270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CWR63_RS18275	COG0601	transmembrane transport
CWR63_RS18285	COG1215	transferase activity, transferring glycosyl groups
CWR63_RS18300	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CWR63_RS18310	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CWR63_RS18325	COG0318	PFAM AMP-dependent synthetase and ligase
CWR63_RS18330	COG2188	Transcriptional regulator
CWR63_RS18335	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CWR63_RS18340	COG2814	Major facilitator Superfamily
CWR63_RS18350	COG0259	pyridoxamine-phosphate oxidase activity
CWR63_RS18355	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CWR63_RS18370	COG0583	DNA-binding transcription factor activity
CWR63_RS18375	COG1960	acyl-CoA dehydrogenase activity
CWR63_RS18385	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR63_RS18390	COG0405	Gamma-glutamyltransferase
CWR63_RS18400	COG3181	Tripartite tricarboxylate transporter family receptor
CWR63_RS18415	COG0802	atpase or kinase
CWR63_RS18420	COG0860	N-Acetylmuramoyl-L-alanine amidase
CWR63_RS18425	COG0586	Pfam SNARE associated Golgi protein
CWR63_RS18455	COG0617	tRNA 3'-terminal CCA addition
CWR63_RS18480	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CWR63_RS18485	COG2188	Transcriptional regulator
CWR63_RS18495	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CWR63_RS18500	COG1234	tRNA 3'-trailer cleavage
CWR63_RS18505	COG1028	Short-chain dehydrogenase reductase Sdr
CWR63_RS18515	COG1028	Short-chain dehydrogenase reductase Sdr
CWR63_RS18520	COG3181	Tripartite tricarboxylate transporter family receptor
CWR63_RS18525	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CWR63_RS18530	COG2301	Belongs to the HpcH HpaI aldolase family
CWR63_RS18535	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR63_RS18540	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
CWR63_RS18550	COG1024	Enoyl-CoA hydratase
CWR63_RS18560	COG2188	Transcriptional regulator
CWR63_RS18565	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CWR63_RS18570	COG0066	3-isopropylmalate dehydratase activity
CWR63_RS18585	COG0752	glycyl-tRNA synthetase alpha subunit
CWR63_RS18590	COG0751	glycine-tRNA ligase activity
CWR63_RS18595	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CWR63_RS18600	COG0204	Acyl-transferase
CWR63_RS18615	COG0242	peptide deformylase activity
CWR63_RS18620	COG1960	acyl-CoA dehydrogenase activity
CWR63_RS18625	COG0700	Nucleoside recognition
CWR63_RS18630	COG0469	pyruvate kinase activity
CWR63_RS18660	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CWR63_RS18670	COG2154	pterin-4-alpha-carbinolamine dehydratase
CWR63_RS18690	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CWR63_RS18695	COG0154	amidase activity
CWR63_RS18705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CWR63_RS18715	COG0747	negative chemotaxis
CWR63_RS18730	COG0019	diaminopimelate decarboxylase activity
CWR63_RS18745	COG3712	iron ion homeostasis
CWR63_RS18750	COG4774	siderophore transport
CWR63_RS18755	COG2353	YceI-like domain
CWR63_RS18760	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CWR63_RS18775	COG0583	DNA-binding transcription factor activity
CWR63_RS18795	COG3384	dioxygenase
CWR63_RS18800	COG0179	Fumarylacetoacetate (FAA) hydrolase
CWR63_RS18835	COG1028	Short-chain dehydrogenase reductase Sdr
CWR63_RS18840	COG1309	transcriptional regulator
CWR63_RS18845	COG2982	Protein involved in outer membrane biogenesis
CWR63_RS18850	COG2818	Glycosylase
CWR63_RS18870	COG1653	transport
CWR63_RS18875	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CWR63_RS18880	COG3842	ATPase activity
CWR63_RS18885	COG0395	ABC-type sugar transport system, permease component
CWR63_RS18910	COG2186	Transcriptional regulator
CWR63_RS18930	COG1454	alcohol dehydrogenase
CWR63_RS18945	COG2011	ABC-type metal ion transport system permease component
CWR63_RS18950	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CWR63_RS18955	COG1501	Belongs to the glycosyl hydrolase 31 family
CWR63_RS18970	COG0318	PFAM AMP-dependent synthetase and ligase
CWR63_RS18975	COG1473	amidohydrolase
CWR63_RS18985	COG2855	membrane
CWR63_RS18995	COG2239	Acts as a magnesium transporter
CWR63_RS19010	COG1522	sequence-specific DNA binding
CWR63_RS19015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CWR63_RS19020	COG1028	Short-chain dehydrogenase reductase Sdr
CWR63_RS19045	COG0739	heme binding
CWR63_RS19055	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CWR63_RS19060	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CWR63_RS19070	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CWR63_RS19075	COG1181	Belongs to the D-alanine--D-alanine ligase family
CWR63_RS19100	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CWR63_RS19105	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CWR63_RS19115	COG3116	cell division
CWR63_RS19120	COG0275	rRNA processing
CWR63_RS19125	COG2001	Belongs to the MraZ family
CWR63_RS19135	COG0488	(ABC) transporter
CWR63_RS19140	COG0418	dihydroorotase activity
CWR63_RS19145	COG1473	amidohydrolase
CWR63_RS19195	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CWR63_RS19200	COG4654	Cytochrome c, class I
CWR63_RS19255	COG2084	Dehydrogenase
CWR63_RS19300	COG0824	Thioesterase
CWR63_RS19305	COG0811	peptide transport
CWR63_RS19310	COG0848	biopolymer transport protein
CWR63_RS19335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CWR63_RS19340	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CWR63_RS19345	COG3181	Tripartite tricarboxylate transporter family receptor
CWR63_RS19360	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CWR63_RS19385	COG0183	Belongs to the thiolase family
CWR63_RS19395	COG1960	acyl-CoA dehydrogenase activity
CWR63_RS19400	COG0583	DNA-binding transcription factor activity
CWR63_RS19405	COG3181	Tripartite tricarboxylate transporter family receptor
CWR63_RS19410	COG1024	Enoyl-CoA hydratase
CWR63_RS19420	COG1253	flavin adenine dinucleotide binding
CWR63_RS19425	COG1285	pathogenesis
CWR63_RS19450	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CWR63_RS19455	COG0697	spore germination
CWR63_RS19465	COG1073	alpha beta
CWR63_RS19490	COG0463	Glycosyl transferase, family 2
CWR63_RS19500	COG0786	glutamate:sodium symporter activity
CWR63_RS19510	COG2031	fatty acid transporter
CWR63_RS19525	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CWR63_RS19530	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CWR63_RS19540	COG0328	RNA-DNA hybrid ribonuclease activity
CWR63_RS19545	COG2226	methyltransferase
CWR63_RS19550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CWR63_RS19555	COG1388	LysM domain
CWR63_RS19555	COG0741	lytic transglycosylase activity
CWR63_RS19570	COG2979	Protein of unknown function (DUF533)
CWR63_RS19590	COG3181	Tripartite tricarboxylate transporter family receptor
CWR63_RS19605	COG3119	arylsulfatase activity
CWR63_RS19630	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CWR63_RS19650	COG0832	Belongs to the urease beta subunit family
CWR63_RS19660	COG0831	urea catabolic process
CWR63_RS19665	COG0829	nickel cation binding
CWR63_RS19680	COG0633	Ferredoxin
CWR63_RS19695	COG2188	Transcriptional regulator
CWR63_RS19700	COG3799	methylaspartate ammonia-lyase activity
CWR63_RS19720	COG2719	SpoVR family
CWR63_RS19725	COG2718	Belongs to the UPF0229 family
CWR63_RS19730	COG2766	serine protein kinase
CWR63_RS19735	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CWR63_RS19735	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CWR63_RS19745	COG4977	sequence-specific DNA binding
CWR63_RS19750	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CWR63_RS19780	COG0316	Belongs to the HesB IscA family
CWR63_RS19800	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CWR63_RS19805	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CWR63_RS19810	COG0312	modulator of DNA gyrase
CWR63_RS19830	COG1116	anion transmembrane transporter activity
CWR63_RS19835	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CWR63_RS19840	COG1335	isochorismatase
CWR63_RS19845	COG0346	lactoylglutathione lyase activity
CWR63_RS19850	COG0513	Belongs to the DEAD box helicase family
CWR63_RS19860	COG1802	Transcriptional regulator
CWR63_RS19865	COG0045	succinate-CoA ligase (ADP-forming) activity
CWR63_RS19865	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CWR63_RS19865	COG1042	CoA-binding domain protein
CWR63_RS19885	COG1522	sequence-specific DNA binding
CWR63_RS19915	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CWR63_RS19920	COG1696	Membrane protein involved in D-alanine export
CWR63_RS19945	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CWR63_RS19960	COG0439	Biotin carboxylase
CWR63_RS19965	COG0511	ligase activity, forming carbon-carbon bonds
CWR63_RS19970	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CWR63_RS19975	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CWR63_RS19980	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CWR63_RS19985	COG3150	esterase
CWR63_RS19990	COG0557	exoribonuclease II activity
CWR63_RS20005	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CWR63_RS20040	COG1678	Uncharacterized ACR, COG1678
CWR63_RS20055	COG0352	thiamine-phosphate diphosphorylase activity
CWR63_RS20085	COG1960	acyl-CoA dehydrogenase activity
CWR63_RS20095	COG1028	Short-chain dehydrogenase reductase Sdr
CWR63_RS20155	COG0494	nUDIX hydrolase
CWR63_RS20180	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
CWR63_RS20205	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CWR63_RS20210	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CWR63_RS20240	COG1126	abc transporter atp-binding protein
CWR63_RS20245	COG0765	amino acid transport
CWR63_RS20250	COG4597	amino acid ABC transporter
CWR63_RS20255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWR63_RS20260	COG2884	Cell division ATP-binding protein ftsE
CWR63_RS20265	COG2177	Part of the ABC transporter FtsEX involved in
CWR63_RS20280	COG1194	a g-specific adenine glycosylase
CWR63_RS20300	COG4206	TonB-dependent receptor
CWR63_RS20305	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CWR63_RS20315	COG0351	phosphomethylpyrimidine kinase
CWR63_RS20320	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CWR63_RS20330	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CWR63_RS20340	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CWR63_RS20355	COG2226	methyltransferase
CWR63_RS20360	COG0745	RESPONSE REGULATOR receiver
CWR63_RS20365	COG5002	protein histidine kinase activity
CWR63_RS20375	COG5002	protein histidine kinase activity
CWR63_RS20385	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CWR63_RS20390	COG0583	DNA-binding transcription factor activity
CWR63_RS20400	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CWR63_RS20405	COG1984	allophanate hydrolase subunit 2
CWR63_RS20420	COG3181	Tripartite tricarboxylate transporter family receptor
CWR63_RS20430	COG1024	Enoyl-CoA hydratase
CWR63_RS20445	COG1802	Transcriptional regulator
CWR63_RS20455	COG1238	metal cluster binding
CWR63_RS20460	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CWR63_RS20465	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CWR63_RS20485	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CWR63_RS20490	COG4988	ABC transporter
CWR63_RS20500	COG1294	oxidase, subunit
CWR63_RS20525	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CWR63_RS20540	COG1137	ATPase activity
CWR63_RS20545	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CWR63_RS20560	COG2010	Cytochrome c
CWR63_RS20560	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CWR63_RS20570	COG1660	Displays ATPase and GTPase activities
CWR63_RS20580	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CWR63_RS20595	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CWR63_RS20600	COG2823	Periplasmic or secreted lipoprotein
CWR63_RS20630	COG0471	metal ion transport
CWR63_RS20635	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CWR63_RS20640	COG0772	Belongs to the SEDS family
CWR63_RS20645	COG0768	penicillin binding
CWR63_RS20655	COG1792	Involved in formation and maintenance of cell shape
CWR63_RS20660	COG1077	Cell shape determining protein MreB Mrl
CWR63_RS20685	COG0708	Exodeoxyribonuclease III
CWR63_RS20695	COG2860	membrane
CWR63_RS20705	COG0583	DNA-binding transcription factor activity
CWR63_RS20710	COG0473	3-isopropylmalate dehydrogenase activity
CWR63_RS20735	COG0583	DNA-binding transcription factor activity
CWR63_RS20740	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CWR63_RS20745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWR63_RS20750	COG0765	amino acid transport
CWR63_RS20755	COG0765	amino acid transport
CWR63_RS20760	COG1126	abc transporter atp-binding protein
CWR63_RS20765	COG1794	racemase activity, acting on amino acids and derivatives
CWR63_RS20770	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CWR63_RS20775	COG2223	nitrite transmembrane transporter activity
CWR63_RS20780	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CWR63_RS20780	COG2813	Specifically methylates the guanine in position
CWR63_RS20790	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CWR63_RS20835	COG0583	DNA-binding transcription factor activity
CWR63_RS20840	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CWR63_RS20845	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CWR63_RS20880	COG0154	amidase activity
CWR63_RS20890	COG1414	Transcriptional regulator
CWR63_RS20900	COG1024	Enoyl-CoA hydratase
CWR63_RS20900	COG1250	3-hydroxyacyl-CoA dehydrogenase
CWR63_RS20910	COG2132	Multicopper oxidase
CWR63_RS20955	COG1024	Enoyl-CoA hydratase
CWR63_RS20960	COG1024	Enoyl-CoA hydratase
CWR63_RS20965	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CWR63_RS20975	COG0747	negative chemotaxis
CWR63_RS20985	COG0601	transmembrane transport
CWR63_RS20990	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CWR63_RS20995	COG0444	Belongs to the ABC transporter superfamily
CWR63_RS21000	COG4608	Belongs to the ABC transporter superfamily
CWR63_RS21010	COG2195	Cleaves the N-terminal amino acid of tripeptides
CWR63_RS21015	COG0210	DNA helicase
CWR63_RS21020	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CWR63_RS21035	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CWR63_RS21055	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CWR63_RS21070	COG0356	it plays a direct role in the translocation of protons across the membrane
CWR63_RS21085	COG1024	Enoyl-CoA hydratase
CWR63_RS21110	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CWR63_RS21120	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CWR63_RS21125	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CWR63_RS21130	COG2967	ApaG domain
CWR63_RS21135	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CWR63_RS21140	COG0546	phosphoglycolate phosphatase activity
CWR63_RS21150	COG0512	Glutamine amidotransferase of anthranilate synthase
CWR63_RS21165	COG1028	Short-chain dehydrogenase reductase Sdr
CWR63_RS21185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CWR63_RS21195	COG1607	acyl-coa hydrolase
CWR63_RS21250	COG1802	Transcriptional regulator
CWR63_RS21280	COG1595	DNA-templated transcription, initiation
CWR63_RS21295	COG3720	iron ion transport
CWR63_RS21300	COG4558	Periplasmic binding protein
CWR63_RS21305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CWR63_RS21315	COG1683	Conserved Protein
CWR63_RS21345	COG3064	Membrane
CWR63_RS21350	COG0583	DNA-binding transcription factor activity
CWR63_RS21360	COG1234	tRNA 3'-trailer cleavage
CWR63_RS21370	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CWR63_RS21375	COG1802	Transcriptional regulator
CWR63_RS21385	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CWR63_RS21405	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR63_RS21425	COG3181	Tripartite tricarboxylate transporter family receptor
CWR63_RS21430	COG0583	DNA-binding transcription factor activity
CWR63_RS21440	COG1522	sequence-specific DNA binding
CWR63_RS21445	COG0183	Belongs to the thiolase family
CWR63_RS21505	COG2814	Major facilitator Superfamily
CWR63_RS21530	COG1999	signal sequence binding
CWR63_RS21575	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CWR63_RS21595	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CWR63_RS21605	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CWR63_RS21615	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CWR63_RS21620	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CWR63_RS21630	COG0067	glutamate synthase
CWR63_RS21630	COG0069	glutamate synthase activity
CWR63_RS21630	COG0070	glutamate synthase
CWR63_RS21640	COG3047	cAMP biosynthetic process
CWR63_RS21650	COG1127	ABC transporter
CWR63_RS21655	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CWR63_RS21660	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CWR63_RS21665	COG2853	Lipoprotein
CWR63_RS21675	COG1131	(ABC) transporter
CWR63_RS21680	COG0842	Transport permease protein
CWR63_RS21700	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CWR63_RS21710	COG0131	Imidazoleglycerol-phosphate dehydratase
CWR63_RS21720	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CWR63_RS21735	COG0140	phosphoribosyl-ATP diphosphatase activity
CWR63_RS21740	COG0537	adenosine 5'-monophosphoramidase activity
CWR63_RS21745	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CWR63_RS21770	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CWR63_RS21780	COG0723	plastoquinol--plastocyanin reductase activity
CWR63_RS21785	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CWR63_RS21790	COG2857	Cytochrome c1
CWR63_RS21795	COG0625	glutathione transferase activity
CWR63_RS21800	COG2969	positive regulation of protein catabolic process
CWR63_RS21830	COG0583	DNA-binding transcription factor activity
CWR63_RS21835	COG0492	ferredoxin-NADP+ reductase activity
CWR63_RS21855	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR63_RS21865	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR63_RS21880	COG3181	Tripartite tricarboxylate transporter family receptor
CWR63_RS21915	COG3702	type iv secretory pathway
CWR63_RS21935	COG3736	Type IV secretory pathway, component VirB8
CWR63_RS21950	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
CWR63_RS21960	COG0697	spore germination
CWR63_RS21980	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CWR63_RS21985	COG0747	negative chemotaxis
CWR63_RS21990	COG0601	transmembrane transport
CWR63_RS21995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CWR63_RS22005	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CWR63_RS22015	COG0513	Belongs to the DEAD box helicase family
CWR63_RS22020	COG1280	lysine exporter protein (LysE YggA)
CWR63_RS22045	COG0583	DNA-binding transcription factor activity
CWR63_RS22055	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CWR63_RS22065	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CWR63_RS22070	COG0154	amidase activity
CWR63_RS22075	COG1609	Transcriptional regulator
CWR63_RS22095	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CWR63_RS22100	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CWR63_RS22105	COG3842	ATPase activity
CWR63_RS22110	COG1653	transport
CWR63_RS22115	COG1175	transmembrane transport
CWR63_RS22120	COG0395	ABC-type sugar transport system, permease component
CWR63_RS22155	COG1280	lysine exporter protein (LysE YggA)
CWR63_RS22170	COG1960	acyl-CoA dehydrogenase activity
CWR63_RS22180	COG0183	Belongs to the thiolase family
CWR63_RS22185	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CWR63_RS22205	COG3181	Tripartite tricarboxylate transporter family receptor
CWR63_RS22215	COG2358	TRAP transporter, solute receptor (TAXI family
CWR63_RS22230	COG2922	Belongs to the Smg family
CWR63_RS22255	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CWR63_RS22260	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CWR63_RS22265	COG1028	Short-chain dehydrogenase reductase Sdr
CWR63_RS22270	COG1012	belongs to the aldehyde dehydrogenase family
CWR63_RS22280	COG0028	Belongs to the TPP enzyme family
CWR63_RS22285	COG1522	sequence-specific DNA binding
CWR63_RS22290	COG3781	membrane
CWR63_RS22320	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CWR63_RS22345	COG1304	FMN binding
CWR63_RS22365	COG1414	Transcriptional regulator
CWR63_RS22380	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CWR63_RS22385	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CWR63_RS22390	COG0594	ribonuclease P activity
CWR63_RS22395	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CWR63_RS22405	COG0753	catalase activity
CWR63_RS22410	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CWR63_RS22415	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CWR63_RS22425	COG2175	clavaminate synthase activity
CWR63_RS22430	COG1473	amidohydrolase
CWR63_RS22435	COG4608	Belongs to the ABC transporter superfamily
CWR63_RS22440	COG0444	Belongs to the ABC transporter superfamily
CWR63_RS22450	COG0601	transmembrane transport
CWR63_RS22455	COG0747	negative chemotaxis
CWR63_RS22495	COG0436	Aminotransferase
CWR63_RS22500	COG1278	Cold shock