locus-tag	class	description
E0718_RS00030	COG1024	Enoyl-CoA hydratase
E0718_RS00035	COG0183	Belongs to the thiolase family
E0718_RS00040	COG3181	Tripartite tricarboxylate transporter family receptor
E0718_RS00055	COG0583	DNA-binding transcription factor activity
E0718_RS00060	COG2267	carboxylic ester hydrolase activity
E0718_RS00075	COG0625	glutathione transferase activity
E0718_RS00080	COG3181	Tripartite tricarboxylate transporter family receptor
E0718_RS00090	COG2186	Transcriptional regulator
E0718_RS00095	COG1012	belongs to the aldehyde dehydrogenase family
E0718_RS00100	COG0626	cystathionine gamma-synthase activity
E0718_RS00140	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
E0718_RS00145	COG0436	Aminotransferase
E0718_RS00150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E0718_RS00155	COG0765	amino acid transport
E0718_RS00165	COG1473	amidohydrolase
E0718_RS00170	COG1414	Transcriptional regulator
E0718_RS00180	COG0154	amidase activity
E0718_RS00240	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
E0718_RS00255	COG3135	benzoate transporter
E0718_RS00300	COG5444	nuclease activity
E0718_RS00420	COG3468	outer membrane autotransporter barrel domain protein
E0718_RS00485	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
E0718_RS00530	COG0489	protein tyrosine kinase activity
E0718_RS00575	COG2081	HI0933 family
E0718_RS00580	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
E0718_RS00595	COG0509	glycine decarboxylation via glycine cleavage system
E0718_RS00620	COG1024	Enoyl-CoA hydratase
E0718_RS00640	COG4172	Belongs to the ABC transporter superfamily
E0718_RS00645	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E0718_RS00650	COG0601	transmembrane transport
E0718_RS00655	COG0747	negative chemotaxis
E0718_RS00665	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
E0718_RS00695	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
E0718_RS00700	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
E0718_RS00715	COG0438	transferase activity, transferring glycosyl groups
E0718_RS00730	COG0438	transferase activity, transferring glycosyl groups
E0718_RS00735	COG0438	transferase activity, transferring glycosyl groups
E0718_RS00740	COG0166	Belongs to the GPI family
E0718_RS00755	COG0277	FAD linked oxidase domain protein
E0718_RS00760	COG0745	RESPONSE REGULATOR receiver
E0718_RS00765	COG0642	Histidine kinase
E0718_RS00770	COG1368	sulfuric ester hydrolase activity
E0718_RS00855	COG0012	GTP binding
E0718_RS00870	COG0745	RESPONSE REGULATOR receiver
E0718_RS00875	COG3181	Tripartite tricarboxylate transporter family receptor
E0718_RS00880	COG1309	transcriptional regulator
E0718_RS00890	COG2814	Major facilitator Superfamily
E0718_RS00915	COG0280	phosphate acetyltransferase
E0718_RS00915	COG0281	malic enzyme
E0718_RS00925	COG0601	transmembrane transport
E0718_RS00930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E0718_RS00935	COG4172	Belongs to the ABC transporter superfamily
E0718_RS00950	COG0583	DNA-binding transcription factor activity
E0718_RS00965	COG0640	Transcriptional regulator
E0718_RS00980	COG3135	benzoate transporter
E0718_RS00985	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
E0718_RS00990	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
E0718_RS00995	COG0742	ribosomal rna small subunit methyltransferase
E0718_RS01010	COG3639	organic phosphonate transmembrane transporter activity
E0718_RS01015	COG3639	organic phosphonate transmembrane transporter activity
E0718_RS01045	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
E0718_RS01050	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
E0718_RS01060	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
E0718_RS01065	COG1058	Belongs to the CinA family
E0718_RS01065	COG1546	Belongs to the CinA family
E0718_RS01070	COG0284	orotidine-5'-phosphate decarboxylase activity
E0718_RS01075	COG1252	NADH dehydrogenase
E0718_RS01100	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
E0718_RS01120	COG1053	succinate dehydrogenase
E0718_RS01130	COG0583	DNA-binding transcription factor activity
E0718_RS01135	COG1053	succinate dehydrogenase
E0718_RS01140	COG3181	Tripartite tricarboxylate transporter family receptor
E0718_RS01145	COG1414	Transcriptional regulator
E0718_RS01160	COG1335	isochorismatase
E0718_RS01175	COG0405	Gamma-glutamyltransferase
E0718_RS01190	COG1960	acyl-CoA dehydrogenase activity
E0718_RS01195	COG1804	L-carnitine dehydratase bile acid-inducible protein F
E0718_RS01200	COG3181	Tripartite tricarboxylate transporter family receptor
E0718_RS01205	COG0583	DNA-binding transcription factor activity
E0718_RS01230	COG3181	Tripartite tricarboxylate transporter family receptor
E0718_RS01235	COG0583	DNA-binding transcription factor activity
E0718_RS01240	COG2199	diguanylate cyclase activity
E0718_RS01295	COG1024	Enoyl-CoA hydratase
E0718_RS01295	COG1250	3-hydroxyacyl-CoA dehydrogenase
E0718_RS01300	COG0318	PFAM AMP-dependent synthetase and ligase
E0718_RS01315	COG1024	Enoyl-CoA hydratase
E0718_RS01320	COG1024	Enoyl-CoA hydratase
E0718_RS01325	COG0318	PFAM AMP-dependent synthetase and ligase
E0718_RS01330	COG1960	acyl-CoA dehydrogenase activity
E0718_RS01370	COG3685	Protein conserved in bacteria
E0718_RS01380	COG0387	Pfam Sodium calcium exchanger
E0718_RS01385	COG3795	YCII-related domain
E0718_RS01390	COG2188	Transcriptional regulator
E0718_RS01410	COG0154	amidase activity
E0718_RS01415	COG1804	L-carnitine dehydratase bile acid-inducible protein F
E0718_RS01420	COG1024	Enoyl-CoA hydratase
E0718_RS01430	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
E0718_RS01445	COG1028	Short-chain dehydrogenase reductase Sdr
E0718_RS01450	COG1414	Transcriptional regulator
E0718_RS01465	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
E0718_RS01470	COG0251	oxidation-reduction process
E0718_RS01475	COG0559	Belongs to the binding-protein-dependent transport system permease family
E0718_RS01495	COG1902	pentaerythritol trinitrate reductase activity
E0718_RS01500	COG0583	DNA-binding transcription factor activity
E0718_RS01510	COG0590	tRNA wobble adenosine to inosine editing
E0718_RS01515	COG2807	transmembrane transport
E0718_RS01520	COG0307	riboflavin synthase, alpha
E0718_RS01525	COG3181	Tripartite tricarboxylate transporter family receptor
E0718_RS01530	COG1522	sequence-specific DNA binding
E0718_RS01540	COG0318	PFAM AMP-dependent synthetase and ligase
E0718_RS01550	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
E0718_RS01590	COG1418	mRNA catabolic process
E0718_RS01600	COG1335	isochorismatase
E0718_RS01625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E0718_RS01630	COG2274	protein secretion by the type I secretion system
E0718_RS01640	COG1538	Outer membrane efflux protein
E0718_RS01645	COG0493	'glutamate synthase
E0718_RS01645	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
E0718_RS01655	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
E0718_RS01665	COG1804	L-carnitine dehydratase bile acid-inducible protein F
E0718_RS01675	COG1309	transcriptional regulator
E0718_RS01680	COG1960	acyl-CoA dehydrogenase activity
E0718_RS01685	COG1028	Short-chain dehydrogenase reductase Sdr
E0718_RS01690	COG2076	Multidrug Resistance protein
E0718_RS01695	COG1309	transcriptional regulator
E0718_RS01715	COG0840	transmembrane signaling receptor activity
E0718_RS01730	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E0718_RS01755	COG1012	belongs to the aldehyde dehydrogenase family
E0718_RS01765	COG1024	Enoyl-CoA hydratase
E0718_RS01775	COG2199	diguanylate cyclase activity
E0718_RS01775	COG2203	Gaf domain
E0718_RS01795	COG0154	amidase activity
E0718_RS01800	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
E0718_RS01800	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
E0718_RS01825	COG3945	hemerythrin HHE cation binding domain
E0718_RS01840	COG2169	Transcriptional regulator
E0718_RS01840	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
E0718_RS01860	COG1271	oxidase subunit
E0718_RS01865	COG1294	oxidase, subunit
E0718_RS01875	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E0718_RS01905	COG0596	Alpha beta hydrolase
E0718_RS01910	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
E0718_RS01945	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
E0718_RS01950	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
E0718_RS01960	COG2070	2-Nitropropane dioxygenase
E0718_RS01975	COG1917	Cupin 2, conserved barrel domain protein
E0718_RS01975	COG2207	Transcriptional regulator
E0718_RS01995	COG2900	Belongs to the SlyX family
E0718_RS02005	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
E0718_RS02035	COG0583	DNA-binding transcription factor activity
E0718_RS02040	COG1804	L-carnitine dehydratase bile acid-inducible protein F
E0718_RS02050	COG0583	DNA-binding transcription factor activity
E0718_RS02075	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
E0718_RS02085	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
E0718_RS02090	COG1845	cytochrome c oxidase, subunit III
E0718_RS02095	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
E0718_RS02100	COG0640	Transcriptional regulator
E0718_RS02165	COG1666	GTP binding
E0718_RS02190	COG1028	Short-chain dehydrogenase reductase Sdr
E0718_RS02200	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
E0718_RS02205	COG1845	cytochrome c oxidase, subunit III
E0718_RS02210	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
E0718_RS02215	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
E0718_RS02220	COG0477	Major facilitator Superfamily
E0718_RS02235	COG5006	permease, DMT superfamily
E0718_RS02255	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
E0718_RS02270	COG3383	formate dehydrogenase (NAD+) activity
E0718_RS02290	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
E0718_RS02295	COG0303	'Molybdopterin
E0718_RS02300	COG0521	Mo-molybdopterin cofactor biosynthetic process
E0718_RS02310	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
E0718_RS02325	COG0412	Dienelactone hydrolase
E0718_RS02335	COG0678	peroxiredoxin activity
E0718_RS02345	COG0697	spore germination
E0718_RS02390	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
E0718_RS02395	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
E0718_RS02400	COG1335	isochorismatase
E0718_RS02405	COG0523	cobalamin synthesis protein
E0718_RS02410	COG3181	Tripartite tricarboxylate transporter family receptor
E0718_RS02425	COG3181	Tripartite tricarboxylate transporter family receptor
E0718_RS02435	COG1802	Transcriptional regulator
E0718_RS02455	COG0667	Aldo Keto reductase
E0718_RS02465	COG4535	Mg2 and Co2 transporter CorC
E0718_RS02475	COG1702	phosphate starvation-inducible protein PhoH
E0718_RS02490	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
E0718_RS02495	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
E0718_RS02500	COG1862	Preprotein translocase
E0718_RS02505	COG0343	queuine tRNA-ribosyltransferase activity
E0718_RS02515	COG2027	D-alanyl-D-alanine carboxypeptidase
E0718_RS02560	COG0741	lytic transglycosylase activity
E0718_RS02570	COG0436	Aminotransferase
E0718_RS02580	COG0280	phosphate acetyltransferase
E0718_RS02580	COG0281	malic enzyme
E0718_RS02590	COG2732	(Barnase) inhibitor
E0718_RS02595	COG1385	rRNA (uridine-N3-)-methyltransferase activity
E0718_RS02600	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
E0718_RS02605	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
E0718_RS02615	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
E0718_RS02620	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
E0718_RS02635	COG0625	glutathione transferase activity
E0718_RS02665	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
E0718_RS02675	COG0306	phosphate transporter
E0718_RS02680	COG0521	Mo-molybdopterin cofactor biosynthetic process
E0718_RS02690	COG0739	heme binding
E0718_RS02700	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
E0718_RS02750	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
E0718_RS02775	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
E0718_RS02780	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
E0718_RS02785	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
E0718_RS02790	COG0009	L-threonylcarbamoyladenylate synthase
E0718_RS02795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E0718_RS02800	COG1414	Transcriptional regulator
E0718_RS02815	COG0765	amino acid transport
E0718_RS02820	COG1126	abc transporter atp-binding protein
E0718_RS02840	COG0028	Belongs to the TPP enzyme family
E0718_RS02845	COG0583	DNA-binding transcription factor activity
E0718_RS02850	COG4974	Belongs to the 'phage' integrase family
E0718_RS02855	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
E0718_RS02860	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
E0718_RS02870	COG1686	Belongs to the peptidase S11 family
E0718_RS02880	COG2814	Major facilitator Superfamily
E0718_RS02890	COG1074	ATP-dependent DNA helicase activity
E0718_RS02900	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
E0718_RS02915	COG1804	L-carnitine dehydratase bile acid-inducible protein F
E0718_RS02920	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
E0718_RS02930	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
E0718_RS02940	COG0505	Belongs to the CarA family
E0718_RS02945	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
E0718_RS02980	COG0613	PHP domain protein
E0718_RS02995	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
E0718_RS02995	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
E0718_RS03000	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
E0718_RS03005	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
E0718_RS03005	COG0047	phosphoribosylformylglycinamidine synthase activity
E0718_RS03010	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
E0718_RS03010	COG3210	domain, Protein
E0718_RS03010	COG3064	Membrane
E0718_RS03030	COG3181	Tripartite tricarboxylate transporter family receptor
E0718_RS03050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
E0718_RS03070	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
E0718_RS03075	COG2197	response regulator
E0718_RS03115	COG1061	Type III restriction enzyme res subunit
E0718_RS03120	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
E0718_RS03140	COG0477	Major facilitator Superfamily
E0718_RS03145	COG2814	Major facilitator Superfamily
E0718_RS03160	COG0625	glutathione transferase activity
E0718_RS03175	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
E0718_RS03190	COG3618	amidohydrolase
E0718_RS03205	COG1804	L-carnitine dehydratase bile acid-inducible protein F
E0718_RS03225	COG2079	MmgE PrpD family protein
E0718_RS03230	COG1012	belongs to the aldehyde dehydrogenase family
E0718_RS03265	COG1280	lysine exporter protein (LysE YggA)
E0718_RS03280	COG0747	negative chemotaxis
E0718_RS03285	COG0601	transmembrane transport
E0718_RS03295	COG4172	Belongs to the ABC transporter superfamily
E0718_RS03300	COG1609	Transcriptional regulator
E0718_RS03315	COG0789	Transcriptional regulator
E0718_RS03340	COG2188	Transcriptional regulator
E0718_RS03345	COG3181	Tripartite tricarboxylate transporter family receptor
E0718_RS03365	COG1802	Transcriptional regulator
E0718_RS03385	COG0842	Transport permease protein
E0718_RS03410	COG0656	L-ascorbic acid biosynthetic process
E0718_RS03415	COG3284	Transcriptional regulator
E0718_RS03420	COG1012	belongs to the aldehyde dehydrogenase family
E0718_RS03435	COG2733	membrane
E0718_RS03440	COG0583	DNA-binding transcription factor activity
E0718_RS03445	COG0384	phenazine biosynthesis protein PhzF
E0718_RS03450	COG5507	3-demethylubiquinone-9 3-methyltransferase
E0718_RS03485	COG0659	secondary active sulfate transmembrane transporter activity
E0718_RS03510	COG1132	(ABC) transporter
E0718_RS03550	COG2207	Transcriptional regulator
E0718_RS03585	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
E0718_RS03590	COG1280	lysine exporter protein (LysE YggA)
E0718_RS03610	COG0625	glutathione transferase activity
E0718_RS03625	COG0697	spore germination
E0718_RS03660	COG3246	L-lysine catabolic process to acetate
E0718_RS03665	COG1250	3-hydroxyacyl-CoA dehydrogenase
E0718_RS03670	COG0583	DNA-binding transcription factor activity
E0718_RS03685	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
E0718_RS03690	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E0718_RS03695	COG3622	Belongs to the hyi family
E0718_RS03705	COG0129	dihydroxy-acid dehydratase activity
E0718_RS03720	COG0129	dihydroxy-acid dehydratase activity
E0718_RS03725	COG3181	Tripartite tricarboxylate transporter family receptor
E0718_RS03735	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
E0718_RS03750	COG2188	Transcriptional regulator
E0718_RS03760	COG0583	DNA-binding transcription factor activity
E0718_RS03770	COG0501	Belongs to the peptidase M48B family
E0718_RS03780	COG2814	Major facilitator Superfamily
E0718_RS03785	COG0583	DNA-binding transcription factor activity
E0718_RS03820	COG4691	Plasmid stability protein
E0718_RS03850	COG2837	iron assimilation
E0718_RS03870	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
E0718_RS03875	COG1335	isochorismatase
E0718_RS03935	COG2346	COG2346, Truncated hemoglobins
E0718_RS03945	COG1126	abc transporter atp-binding protein
E0718_RS03950	COG0765	amino acid transport
E0718_RS03955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E0718_RS03965	COG0789	Transcriptional regulator
E0718_RS03975	COG0165	Argininosuccinate lyase
E0718_RS03980	COG0668	transmembrane transport
E0718_RS04030	COG0747	negative chemotaxis
E0718_RS04035	COG0601	transmembrane transport
E0718_RS04040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E0718_RS04050	COG1280	lysine exporter protein (LysE YggA)
E0718_RS04070	COG3161	chorismate lyase activity
E0718_RS04075	COG1187	pseudouridine synthase activity
E0718_RS04085	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E0718_RS04105	COG1999	signal sequence binding
E0718_RS04110	COG0339	signal peptide processing
E0718_RS04115	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
E0718_RS04120	COG4566	intracellular signal transduction
E0718_RS04130	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
E0718_RS04135	COG0508	dehydrogenase complex catalyzes the overall conversion of
E0718_RS04140	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E0718_RS04145	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
E0718_RS04175	COG0745	RESPONSE REGULATOR receiver
E0718_RS04180	COG0643	Histidine kinase
E0718_RS04180	COG2198	Histidine kinase
E0718_RS04190	COG0840	transmembrane signaling receptor activity
E0718_RS04195	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
E0718_RS04205	COG0745	RESPONSE REGULATOR receiver
E0718_RS04210	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
E0718_RS04245	COG1815	bacterial-type flagellum-dependent cell motility
E0718_RS04250	COG1558	bacterial-type flagellum-dependent cell motility
E0718_RS04260	COG1749	Flagellar hook protein flgE
E0718_RS04290	COG1256	bacterial-type flagellum assembly
E0718_RS04300	COG0840	transmembrane signaling receptor activity
E0718_RS04320	COG1338	Plays a role in the flagellum-specific transport system
E0718_RS04340	COG1580	Controls the rotational direction of flagella during chemotaxis
E0718_RS04355	COG1157	protein secretion by the type III secretion system
E0718_RS04360	COG1317	bacterial-type flagellum organization
E0718_RS04365	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
E0718_RS04375	COG1677	Flagellar hook-basal body complex protein FliE
E0718_RS04385	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
E0718_RS04415	COG0285	dihydrofolate synthase activity
E0718_RS04450	COG0024	Methionine aminopeptidase
E0718_RS04455	COG0052	Belongs to the universal ribosomal protein uS2 family
E0718_RS04470	COG0233	cytoplasmic translational termination
E0718_RS04475	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
E0718_RS04490	COG0750	zinc metalloprotease
E0718_RS04495	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E0718_RS04500	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
E0718_RS04525	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
E0718_RS04530	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
E0718_RS04555	COG0330	HflC and HflK could
E0718_RS04570	COG2867	negative regulation of translational initiation
E0718_RS04580	COG1960	acyl-CoA dehydrogenase activity
E0718_RS04585	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
E0718_RS04610	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
E0718_RS04615	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
E0718_RS04620	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
E0718_RS04625	COG0084	hydrolase, TatD family'
E0718_RS04650	COG1126	abc transporter atp-binding protein
E0718_RS04660	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
E0718_RS04665	COG1012	belongs to the aldehyde dehydrogenase family
E0718_RS04675	COG0028	Belongs to the TPP enzyme family
E0718_RS04705	COG3189	MarR family transcriptional regulator
E0718_RS04735	COG1595	DNA-templated transcription, initiation
E0718_RS04745	COG0861	Integral membrane protein TerC family
E0718_RS04770	COG2988	succinylglutamate desuccinylase activity
E0718_RS04785	COG1253	flavin adenine dinucleotide binding
E0718_RS04795	COG3181	Tripartite tricarboxylate transporter family receptor
E0718_RS04800	COG2084	Dehydrogenase
E0718_RS04835	COG2814	Major facilitator Superfamily
E0718_RS04845	COG0583	DNA-binding transcription factor activity
E0718_RS04875	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
E0718_RS04880	COG4943	cyclic-guanylate-specific phosphodiesterase activity
E0718_RS04885	COG0840	transmembrane signaling receptor activity
E0718_RS04910	COG3468	outer membrane autotransporter barrel domain protein
E0718_RS04915	COG3468	outer membrane autotransporter barrel domain protein
E0718_RS04950	COG5265	(ABC) transporter
E0718_RS04960	COG0667	Aldo Keto reductase
E0718_RS04975	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
E0718_RS05015	COG1959	2 iron, 2 sulfur cluster binding
E0718_RS05040	COG0400	carboxylic ester hydrolase activity
E0718_RS05050	COG1566	PFAM secretion protein HlyD family protein
E0718_RS05075	COG0235	Class ii aldolase
E0718_RS05080	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
E0718_RS05085	COG0720	synthase
E0718_RS05090	COG0602	queuosine metabolic process
E0718_RS05110	COG4208	sulfate ABC transporter
E0718_RS05120	COG0175	sulfate reduction
E0718_RS05150	COG0335	large ribosomal subunit rRNA binding
E0718_RS05160	COG0667	Aldo Keto reductase
E0718_RS05165	COG1162	GTPase activity
E0718_RS05170	COG0501	Belongs to the peptidase M48B family
E0718_RS05175	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
E0718_RS05185	COG3327	negative regulation of DNA-templated transcription, initiation
E0718_RS05190	COG3396	Phenylacetate-CoA oxygenase
E0718_RS05195	COG3460	Phenylacetate-CoA oxygenase
E0718_RS05200	COG3396	Phenylacetate-CoA oxygenase
E0718_RS05205	COG2151	metal-sulfur cluster biosynthetic enzyme
E0718_RS05210	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
E0718_RS05215	COG1012	belongs to the aldehyde dehydrogenase family
E0718_RS05220	COG1024	Enoyl-CoA hydratase
E0718_RS05225	COG2050	protein possibly involved in aromatic compounds catabolism
E0718_RS05240	COG3539	Fimbrial protein
E0718_RS05245	COG3539	Fimbrial protein
E0718_RS05250	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
E0718_RS05250	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
E0718_RS05260	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
E0718_RS05265	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
E0718_RS05280	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
E0718_RS05285	COG3842	ATPase activity
E0718_RS05290	COG1176	ABC-type spermidine putrescine transport system, permease component I
E0718_RS05295	COG1177	transmembrane transport
E0718_RS05320	COG1960	acyl-CoA dehydrogenase activity
E0718_RS05330	COG0704	Plays a role in the regulation of phosphate uptake
E0718_RS05340	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
E0718_RS05345	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
E0718_RS05345	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
E0718_RS05350	COG1643	Atp-dependent helicase
E0718_RS05365	COG0438	transferase activity, transferring glycosyl groups
E0718_RS05370	COG0726	polysaccharide deacetylase
E0718_RS05375	COG0463	Glycosyl transferase, family 2
E0718_RS05380	COG0438	transferase activity, transferring glycosyl groups
E0718_RS05385	COG2194	sulfuric ester hydrolase activity
E0718_RS05410	COG0859	PFAM glycosyl transferase family 9
E0718_RS05415	COG1132	(ABC) transporter
E0718_RS05430	COG0077	Prephenate dehydratase
E0718_RS05435	COG1530	ribonuclease E activity
E0718_RS05475	COG1250	3-hydroxyacyl-CoA dehydrogenase
E0718_RS05480	COG0154	amidase activity
E0718_RS05510	COG2814	Major facilitator Superfamily
E0718_RS05530	COG0267	Belongs to the bacterial ribosomal protein bL33 family
E0718_RS05535	COG0227	Belongs to the bacterial ribosomal protein bL28 family
E0718_RS05540	COG2814	Major facilitator Superfamily
E0718_RS05545	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
E0718_RS05555	COG4176	ABC-type proline glycine betaine transport system permease component
E0718_RS05565	COG1942	4-Oxalocrotonate Tautomerase
E0718_RS05570	COG0183	Belongs to the thiolase family
E0718_RS05580	COG1802	Transcriptional regulator
E0718_RS05590	COG1024	Enoyl-CoA hydratase
E0718_RS05595	COG0318	PFAM AMP-dependent synthetase and ligase
E0718_RS05605	COG2032	superoxide dismutase activity
E0718_RS05620	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
E0718_RS05645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E0718_RS05660	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
E0718_RS05665	COG0736	holo-[acyl-carrier-protein] synthase activity
E0718_RS05680	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
E0718_RS05695	COG2224	Isocitrate lyase
E0718_RS05705	COG1346	cytolysis
E0718_RS05710	COG1380	Effector of murein hydrolase LrgA
E0718_RS05715	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
E0718_RS05715	COG4106	trans-aconitate 2-methyltransferase activity
E0718_RS05745	COG3278	Belongs to the heme-copper respiratory oxidase family
E0718_RS05790	COG1131	(ABC) transporter
E0718_RS05795	COG0842	Transport permease protein
E0718_RS05800	COG0628	permease
E0718_RS05815	COG2814	Major facilitator Superfamily
E0718_RS05820	COG2841	Protein conserved in bacteria
E0718_RS05845	COG0765	amino acid transport
E0718_RS05850	COG0765	amino acid transport
E0718_RS05855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E0718_RS05890	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E0718_RS05895	COG1595	DNA-templated transcription, initiation
E0718_RS05905	COG3530	Putative quorum-sensing-regulated virulence factor
E0718_RS05910	COG0494	nUDIX hydrolase
E0718_RS05925	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
E0718_RS05935	COG3468	outer membrane autotransporter barrel domain protein
E0718_RS05950	COG5564	TIM-barrel signal transduction protein
E0718_RS05965	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
E0718_RS06000	COG1131	(ABC) transporter
E0718_RS06020	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
E0718_RS06020	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
E0718_RS06025	COG1562	ergosterol biosynthetic process
E0718_RS06030	COG1562	ergosterol biosynthetic process
E0718_RS06035	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
E0718_RS06055	COG2304	oxidoreductase activity
E0718_RS06115	COG1047	Peptidyl-prolyl cis-trans
E0718_RS06120	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
E0718_RS06125	COG0625	glutathione transferase activity
E0718_RS06145	COG0523	cobalamin synthesis protein
E0718_RS06155	COG0583	DNA-binding transcription factor activity
E0718_RS06165	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
E0718_RS06170	COG1187	pseudouridine synthase activity
E0718_RS06180	COG2251	uridine kinase activity
E0718_RS06180	COG0195	Participates in both transcription termination and antitermination
E0718_RS06215	COG1611	Belongs to the LOG family
E0718_RS06230	COG0412	Dienelactone hydrolase
E0718_RS06235	COG1283	sodium-dependent phosphate transmembrane transporter activity
E0718_RS06240	COG1760	l-serine dehydratase
E0718_RS06245	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
E0718_RS06260	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
E0718_RS06285	COG2311	Membrane
E0718_RS06295	COG2358	TRAP transporter, solute receptor (TAXI family
E0718_RS06300	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
E0718_RS06340	COG3395	kinase activity
E0718_RS06345	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
E0718_RS06380	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
E0718_RS06420	COG4964	Belongs to the GSP D family
E0718_RS06455	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
E0718_RS06465	COG1295	ribonuclease BN
E0718_RS06480	COG0745	RESPONSE REGULATOR receiver
E0718_RS06485	COG2205	protein histidine kinase activity
E0718_RS06490	COG5001	Diguanylate cyclase
E0718_RS06505	COG1763	Mo-molybdopterin cofactor biosynthetic process
E0718_RS06510	COG0303	'Molybdopterin
E0718_RS06515	COG0746	molybdenum cofactor guanylyltransferase activity
E0718_RS06520	COG0489	protein tyrosine kinase activity
E0718_RS06550	COG3383	formate dehydrogenase (NAD+) activity
E0718_RS06550	COG0243	molybdopterin cofactor binding
E0718_RS06555	COG0437	4 iron, 4 sulfur cluster binding
E0718_RS06585	COG1122	ATPase activity
E0718_RS06610	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
E0718_RS06625	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
E0718_RS06685	COG0635	Involved in the biosynthesis of porphyrin-containing compound
E0718_RS06695	COG2197	response regulator
E0718_RS06700	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
E0718_RS06705	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
E0718_RS06720	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
E0718_RS06725	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
E0718_RS06735	COG1764	response to oxidative stress
E0718_RS06740	COG2423	ornithine cyclodeaminase activity
E0718_RS06750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E0718_RS06755	COG0765	amino acid transport
E0718_RS06760	COG0765	amino acid transport
E0718_RS06765	COG1126	abc transporter atp-binding protein
E0718_RS06790	COG1522	sequence-specific DNA binding
E0718_RS06800	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
E0718_RS06805	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
E0718_RS06815	COG0196	riboflavin kinase activity
E0718_RS06820	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
E0718_RS06825	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
E0718_RS06825	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
E0718_RS06840	COG0210	DNA helicase
E0718_RS06845	COG4771	TonB-dependent receptor
E0718_RS06850	COG0488	(ABC) transporter
E0718_RS06855	COG2890	protein-(glutamine-N5) methyltransferase activity
E0718_RS06870	COG0436	Aminotransferase
E0718_RS06900	COG1278	Cold shock
E0718_RS06910	COG1278	Cold shock
E0718_RS06925	COG0740	serine-type endopeptidase activity
E0718_RS06935	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
E0718_RS06940	COG0583	DNA-binding transcription factor activity
E0718_RS06945	COG1804	L-carnitine dehydratase bile acid-inducible protein F
E0718_RS06960	COG1024	Enoyl-CoA hydratase
E0718_RS06975	COG1028	Short-chain dehydrogenase reductase Sdr
E0718_RS06980	COG1960	acyl-CoA dehydrogenase activity
E0718_RS06995	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
E0718_RS07005	COG3468	outer membrane autotransporter barrel domain protein
E0718_RS07025	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
E0718_RS07035	COG1104	cysteine desulfurase activity
E0718_RS07040	COG0822	iron-sulfur transferase activity
E0718_RS07045	COG0316	Belongs to the HesB IscA family
E0718_RS07060	COG0633	Ferredoxin
E0718_RS07075	COG1024	Enoyl-CoA hydratase
E0718_RS07105	COG1022	Amp-dependent synthetase and ligase
E0718_RS07125	COG1028	Short-chain dehydrogenase reductase Sdr
E0718_RS07135	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
E0718_RS07150	COG1136	(ABC) transporter
E0718_RS07155	COG0084	hydrolase, TatD family'
E0718_RS07170	COG4221	oxidoreductase activity
E0718_RS07175	COG0406	alpha-ribazole phosphatase activity
E0718_RS07185	COG3842	ATPase activity
E0718_RS07200	COG2233	PERMEase
E0718_RS07205	COG0840	transmembrane signaling receptor activity
E0718_RS07210	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
E0718_RS07220	COG1534	Rna-binding protein
E0718_RS07230	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
E0718_RS07250	COG0248	Ppx GppA phosphatase
E0718_RS07380	COG0559	Belongs to the binding-protein-dependent transport system permease family
E0718_RS07415	COG2072	flavoprotein involved in K transport
E0718_RS07420	COG1250	3-hydroxyacyl-CoA dehydrogenase
E0718_RS07450	COG1137	ATPase activity
E0718_RS07460	COG0154	amidase activity
E0718_RS07465	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
E0718_RS07485	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
E0718_RS07490	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
E0718_RS07495	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
E0718_RS07505	COG0179	Fumarylacetoacetate (FAA) hydrolase
E0718_RS07515	COG1522	sequence-specific DNA binding
E0718_RS07520	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
E0718_RS07525	COG1473	amidohydrolase
E0718_RS07530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E0718_RS07535	COG4597	amino acid ABC transporter
E0718_RS07540	COG0765	amino acid transport
E0718_RS07545	COG1126	abc transporter atp-binding protein
E0718_RS07560	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
E0718_RS07590	COG3181	Tripartite tricarboxylate transporter family receptor
E0718_RS07610	COG0583	DNA-binding transcription factor activity
E0718_RS07645	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
E0718_RS07685	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
E0718_RS07695	COG1132	(ABC) transporter
E0718_RS07720	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
E0718_RS07730	COG1012	belongs to the aldehyde dehydrogenase family
E0718_RS07740	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
E0718_RS07750	COG0511	ligase activity, forming carbon-carbon bonds
E0718_RS07775	COG2188	Transcriptional regulator
E0718_RS07780	COG0439	Biotin carboxylase
E0718_RS07790	COG0511	ligase activity, forming carbon-carbon bonds
E0718_RS07805	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
E0718_RS07835	COG3971	2-oxopent-4-enoate hydratase activity
E0718_RS07840	COG0583	DNA-binding transcription factor activity
E0718_RS07855	COG0179	Fumarylacetoacetate (FAA) hydrolase
E0718_RS07905	COG1028	Short-chain dehydrogenase reductase Sdr
E0718_RS07945	COG0251	oxidation-reduction process
E0718_RS08045	COG4669	(LipO)protein
E0718_RS08080	COG4790	Type iii secretion
E0718_RS08085	COG4794	Type iii secretion
E0718_RS08090	COG4791	protein targeting
E0718_RS08095	COG4792	protein secretion
E0718_RS08130	COG2770	Histidine kinase
E0718_RS08130	COG2208	phosphoserine phosphatase activity
E0718_RS08140	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
E0718_RS08150	COG1366	Belongs to the anti-sigma-factor antagonist family
E0718_RS08155	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
E0718_RS08195	COG2321	neutral zinc metallopeptidase
E0718_RS08200	COG0009	L-threonylcarbamoyladenylate synthase
E0718_RS08205	COG1994	Peptidase M50
E0718_RS08210	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
E0718_RS08215	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
E0718_RS08220	COG3539	Fimbrial protein
E0718_RS08230	COG2850	peptidyl-arginine hydroxylation
E0718_RS08240	COG3360	Dodecin
E0718_RS08275	COG0668	transmembrane transport
E0718_RS08295	COG0483	inositol monophosphate 1-phosphatase activity
E0718_RS08300	COG1253	flavin adenine dinucleotide binding
E0718_RS08320	COG3063	Type IV pilus biogenesis stability protein PilW
E0718_RS08335	COG0825	malonyl-CoA metabolic process
E0718_RS08345	COG0527	aspartate kinase activity
E0718_RS08370	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
E0718_RS08370	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
E0718_RS08385	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
E0718_RS08395	COG1028	Short-chain dehydrogenase reductase Sdr
E0718_RS08405	COG0583	DNA-binding transcription factor activity
E0718_RS08430	COG3842	ATPase activity
E0718_RS08440	COG0446	pyridine nucleotide-disulphide oxidoreductase
E0718_RS08440	COG1902	pentaerythritol trinitrate reductase activity
E0718_RS08445	COG1414	Transcriptional regulator
E0718_RS08450	COG1832	CoA-binding protein
E0718_RS08460	COG0251	oxidation-reduction process
E0718_RS08485	COG1902	pentaerythritol trinitrate reductase activity
E0718_RS08495	COG1215	transferase activity, transferring glycosyl groups
E0718_RS08500	COG1649	PFAM Uncharacterised BCR, COG1649
E0718_RS08500	COG0726	polysaccharide deacetylase
E0718_RS08520	COG1846	Transcriptional regulator
E0718_RS08550	COG2080	2 iron, 2 sulfur cluster binding
E0718_RS08555	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E0718_RS08565	COG0596	Alpha beta hydrolase
E0718_RS08570	COG2309	aminopeptidase activity
E0718_RS08575	COG1335	isochorismatase
E0718_RS08580	COG1529	Aldehyde oxidase and xanthine dehydrogenase
E0718_RS08580	COG2010	Cytochrome c
E0718_RS08585	COG1017	nitric oxide dioxygenase activity
E0718_RS08585	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
E0718_RS08600	COG3181	Tripartite tricarboxylate transporter family receptor
E0718_RS08610	COG0318	PFAM AMP-dependent synthetase and ligase
E0718_RS08620	COG0183	Belongs to the thiolase family
E0718_RS08625	COG1024	Enoyl-CoA hydratase
E0718_RS08625	COG1250	3-hydroxyacyl-CoA dehydrogenase
E0718_RS08640	COG0183	Belongs to the thiolase family
E0718_RS08655	COG2197	response regulator
E0718_RS08670	COG0166	Belongs to the GPI family
E0718_RS08675	COG1045	serine acetyltransferase
E0718_RS08700	COG0483	inositol monophosphate 1-phosphatase activity
E0718_RS08710	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
E0718_RS08730	COG0598	Magnesium transport protein CorA
E0718_RS08740	COG0747	negative chemotaxis
E0718_RS08745	COG0601	transmembrane transport
E0718_RS08750	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E0718_RS08755	COG4172	Belongs to the ABC transporter superfamily
E0718_RS08805	COG4964	Belongs to the GSP D family
E0718_RS08870	COG3474	cytochrome
E0718_RS08875	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
E0718_RS08890	COG3384	dioxygenase
E0718_RS08895	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
E0718_RS08915	COG2885	chlorophyll binding
E0718_RS08950	COG0697	spore germination
E0718_RS08955	COG0730	response to heat
E0718_RS08970	COG3264	Mechanosensitive ion channel
E0718_RS08970	COG1511	domain protein
E0718_RS08975	COG0583	DNA-binding transcription factor activity
E0718_RS08980	COG0427	acetyl-CoA hydrolase
E0718_RS08985	COG0385	Bile acid
E0718_RS09025	COG3468	outer membrane autotransporter barrel domain protein
E0718_RS09040	COG0799	negative regulation of ribosome biogenesis
E0718_RS09055	COG0151	Belongs to the GarS family
E0718_RS09065	COG0433	COG0433 Predicted ATPase
E0718_RS09070	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
E0718_RS09080	COG1012	belongs to the aldehyde dehydrogenase family
E0718_RS09105	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
E0718_RS09115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E0718_RS09125	COG0747	negative chemotaxis
E0718_RS09135	COG0473	3-isopropylmalate dehydrogenase activity
E0718_RS09155	COG1846	Transcriptional regulator
E0718_RS09165	COG0697	spore germination
E0718_RS09175	COG0501	Belongs to the peptidase M48B family
E0718_RS09195	COG0583	DNA-binding transcription factor activity
E0718_RS09200	COG3842	ATPase activity
E0718_RS09205	COG1178	ABC-type Fe3 transport system permease component
E0718_RS09210	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E0718_RS09215	COG1840	ABC-type Fe3 transport system, periplasmic component
E0718_RS09250	COG3181	Tripartite tricarboxylate transporter family receptor
E0718_RS09260	COG1722	exodeoxyribonuclease VII activity
E0718_RS09265	COG0142	geranyltranstransferase activity
E0718_RS09275	COG1469	GTP cyclohydrolase I activity
E0718_RS09280	COG0360	Binds together with S18 to 16S ribosomal RNA
E0718_RS09285	COG2965	DNA replication, synthesis of RNA primer
E0718_RS09290	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
E0718_RS09310	COG0305	Participates in initiation and elongation during chromosome replication
E0718_RS09320	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
E0718_RS09325	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
E0718_RS09330	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E0718_RS09335	COG3737	Protein of unknown function (DUF498/DUF598)
E0718_RS09340	COG0436	Aminotransferase
E0718_RS09360	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
E0718_RS09365	COG0308	aminopeptidase N
E0718_RS09385	COG0312	modulator of DNA gyrase
E0718_RS09390	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
E0718_RS09395	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
E0718_RS09395	COG3064	Membrane
E0718_RS09395	COG3064	Membrane
E0718_RS09395	COG3210	domain, Protein
E0718_RS09395	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
E0718_RS09395	COG3210	domain, Protein
E0718_RS09400	COG0277	FAD linked oxidase domain protein
E0718_RS09405	COG0277	FAD linked oxidase domain protein
E0718_RS09415	COG0247	lactate metabolic process
E0718_RS09420	COG2819	hydrolase of the alpha beta superfamily
E0718_RS09460	COG0583	DNA-binding transcription factor activity
E0718_RS09470	COG0730	response to heat
E0718_RS09475	COG0625	glutathione transferase activity
E0718_RS09480	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
E0718_RS09485	COG3909	cytochrome
E0718_RS09520	COG3706	GGDEF domain
E0718_RS09560	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
E0718_RS09570	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
E0718_RS09575	COG0069	glutamate synthase activity
E0718_RS09580	COG2391	methyltransferase activity
E0718_RS09585	COG0679	Auxin Efflux Carrier
E0718_RS09610	COG0557	exoribonuclease II activity
E0718_RS09615	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
E0718_RS09625	COG3128	pkhd-type hydroxylase
E0718_RS09630	COG0776	regulation of translation
E0718_RS09660	COG0642	Histidine kinase
E0718_RS09665	COG3158	transport of potassium into the cell
E0718_RS09675	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
E0718_RS09690	COG0583	DNA-binding transcription factor activity
E0718_RS09700	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
E0718_RS09720	COG2186	Transcriptional regulator
E0718_RS09725	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
E0718_RS09745	COG0268	Binds directly to 16S ribosomal RNA
E0718_RS09755	COG0728	peptidoglycan biosynthetic process
E0718_RS09775	COG2835	tetraacyldisaccharide 4'-kinase activity
E0718_RS09785	COG0848	biopolymer transport protein
E0718_RS09790	COG0811	peptide transport
E0718_RS09800	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
E0718_RS09805	COG0038	chloride channel
E0718_RS09810	COG0183	Belongs to the thiolase family
E0718_RS09820	COG1278	Cold shock
E0718_RS09835	COG4953	penicillin-binding protein 1C
E0718_RS09840	COG0542	response to heat
E0718_RS09845	COG2995	paraquat-inducible protein a
E0718_RS09850	COG3008	intermembrane lipid transfer
E0718_RS09850	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
E0718_RS09860	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
E0718_RS09860	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
E0718_RS09860	COG0506	proline dehydrogenase activity
E0718_RS09895	COG1309	transcriptional regulator
E0718_RS09910	COG0004	ammonium transporteR
E0718_RS09935	COG0291	Belongs to the bacterial ribosomal protein bL35 family
E0718_RS09940	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
E0718_RS09980	COG0500	methyltransferase
E0718_RS09995	COG2367	Beta-lactamase
E0718_RS10005	COG1522	sequence-specific DNA binding
E0718_RS10020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E0718_RS10055	COG0540	Belongs to the ATCase OTCase family
E0718_RS10070	COG1804	L-carnitine dehydratase bile acid-inducible protein F
E0718_RS10075	COG0583	DNA-binding transcription factor activity
E0718_RS10080	COG0183	Belongs to the thiolase family
E0718_RS10095	COG1028	Short-chain dehydrogenase reductase Sdr
E0718_RS10110	COG3842	ATPase activity
E0718_RS10115	COG1024	Enoyl-CoA hydratase
E0718_RS10115	COG1250	3-hydroxyacyl-CoA dehydrogenase
E0718_RS10135	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
E0718_RS10140	COG2137	regulation of response to DNA damage stimulus
E0718_RS10160	COG0045	succinate-CoA ligase (ADP-forming) activity
E0718_RS10165	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
E0718_RS10170	COG0861	Integral membrane protein TerC family
E0718_RS10175	COG0861	Integral membrane protein TerC family
E0718_RS10220	COG2204	response regulator
E0718_RS10225	COG2204	response regulator
E0718_RS10230	COG0028	Belongs to the TPP enzyme family
E0718_RS10285	COG1028	Short-chain dehydrogenase reductase Sdr
E0718_RS10295	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
E0718_RS10300	COG4575	ribosome binding
E0718_RS10320	COG1546	Belongs to the CinA family
E0718_RS10320	COG1058	Belongs to the CinA family
E0718_RS10335	COG0392	lysyltransferase activity
E0718_RS10345	COG3568	Endonuclease Exonuclease Phosphatase
E0718_RS10355	COG1695	Transcriptional regulator
E0718_RS10375	COG0583	DNA-binding transcription factor activity
E0718_RS10405	COG3181	Tripartite tricarboxylate transporter family receptor
E0718_RS10410	COG4948	Mandelate Racemase Muconate Lactonizing
E0718_RS10440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
E0718_RS10475	COG3005	denitrification pathway
E0718_RS10480	COG3043	anaerobic respiration
E0718_RS10500	COG0330	HflC and HflK could
E0718_RS10525	COG0583	DNA-binding transcription factor activity
E0718_RS10530	COG1028	Short-chain dehydrogenase reductase Sdr
E0718_RS10560	COG0431	NADPH-dependent FMN reductase
E0718_RS10585	COG0824	Thioesterase
E0718_RS10590	COG1454	alcohol dehydrogenase
E0718_RS10600	COG1024	Enoyl-CoA hydratase
E0718_RS10600	COG1250	3-hydroxyacyl-CoA dehydrogenase
E0718_RS10605	COG3181	Tripartite tricarboxylate transporter family receptor
E0718_RS10615	COG1024	Enoyl-CoA hydratase
E0718_RS10625	COG3181	Tripartite tricarboxylate transporter family receptor
E0718_RS10630	COG0583	DNA-binding transcription factor activity
E0718_RS10635	COG1028	Short-chain dehydrogenase reductase Sdr
E0718_RS10650	COG0183	Belongs to the thiolase family
E0718_RS10655	COG1804	L-carnitine dehydratase bile acid-inducible protein F
E0718_RS10670	COG3119	arylsulfatase activity
E0718_RS10685	COG0625	glutathione transferase activity
E0718_RS10690	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
E0718_RS10695	COG2944	sequence-specific DNA binding
E0718_RS10705	COG2197	response regulator
E0718_RS10725	COG3119	arylsulfatase activity
E0718_RS10765	COG1262	PFAM Formylglycine-generating sulfatase enzyme
E0718_RS10780	COG1028	Short-chain dehydrogenase reductase Sdr
E0718_RS10785	COG0861	Integral membrane protein TerC family
E0718_RS10810	COG2267	carboxylic ester hydrolase activity
E0718_RS10815	COG1228	amidohydrolase
E0718_RS10825	COG0179	Fumarylacetoacetate (FAA) hydrolase
E0718_RS10835	COG1172	Belongs to the binding-protein-dependent transport system permease family
E0718_RS10855	COG0583	DNA-binding transcription factor activity
E0718_RS10860	COG3181	Tripartite tricarboxylate transporter family receptor
E0718_RS10885	COG2188	Transcriptional regulator
E0718_RS10895	COG1028	Short-chain dehydrogenase reductase Sdr
E0718_RS10900	COG1414	Transcriptional regulator
E0718_RS10915	COG1176	ABC-type spermidine putrescine transport system, permease component I
E0718_RS10920	COG0395	ABC-type sugar transport system, permease component
E0718_RS10935	COG0439	Biotin carboxylase
E0718_RS10940	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
E0718_RS10945	COG1804	L-carnitine dehydratase bile acid-inducible protein F
E0718_RS10965	COG0833	amino acid
E0718_RS10995	COG3829	transcription factor binding
E0718_RS11005	COG4943	cyclic-guanylate-specific phosphodiesterase activity
E0718_RS11025	COG1804	L-carnitine dehydratase bile acid-inducible protein F
E0718_RS11030	COG1012	belongs to the aldehyde dehydrogenase family
E0718_RS11050	COG0583	DNA-binding transcription factor activity
E0718_RS11055	COG4692	amylo-alpha-1,6-glucosidase activity
E0718_RS11065	COG0183	Belongs to the thiolase family
E0718_RS11080	COG1804	L-carnitine dehydratase bile acid-inducible protein F
E0718_RS11085	COG0633	Ferredoxin
E0718_RS11095	COG1024	Enoyl-CoA hydratase
E0718_RS11105	COG4638	Rieske (2fe-2S)
E0718_RS11110	COG0683	leucine binding
E0718_RS11115	COG0559	Belongs to the binding-protein-dependent transport system permease family
E0718_RS11175	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
E0718_RS11185	COG0828	Belongs to the bacterial ribosomal protein bS21 family
E0718_RS11190	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
E0718_RS11205	COG0330	HflC and HflK could
E0718_RS11210	COG0330	HflC and HflK could
E0718_RS11215	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
E0718_RS11220	COG1923	regulation of RNA biosynthetic process
E0718_RS11230	COG1160	GTP binding
E0718_RS11235	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E0718_RS11240	COG2976	Protein conserved in bacteria
E0718_RS11265	COG0105	UTP biosynthetic process
E0718_RS11285	COG0642	Histidine kinase
E0718_RS11295	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
E0718_RS11320	COG0425	Belongs to the sulfur carrier protein TusA family
E0718_RS11375	COG4172	Belongs to the ABC transporter superfamily
E0718_RS11380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E0718_RS11385	COG0601	transmembrane transport
E0718_RS11390	COG0747	negative chemotaxis
E0718_RS11415	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
E0718_RS11465	COG1640	4-alpha-glucanotransferase
E0718_RS11510	COG0667	Aldo Keto reductase
E0718_RS11525	COG2259	Doxx family
E0718_RS11565	COG0386	Belongs to the glutathione peroxidase family
E0718_RS11570	COG0625	glutathione transferase activity
E0718_RS11585	COG0095	Lipoate-protein ligase
E0718_RS11600	COG0688	phosphatidylethanolamine metabolic process
E0718_RS11610	COG1464	Belongs to the NlpA lipoprotein family
E0718_RS11625	COG2363	Small membrane protein
E0718_RS11650	COG2133	pyrroloquinoline quinone binding
E0718_RS11655	COG0625	glutathione transferase activity
E0718_RS11660	COG1794	racemase activity, acting on amino acids and derivatives
E0718_RS11680	COG0559	Belongs to the binding-protein-dependent transport system permease family
E0718_RS11690	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
E0718_RS11700	COG1653	transport
E0718_RS11705	COG1175	transmembrane transport
E0718_RS11710	COG0395	ABC-type sugar transport system, permease component
E0718_RS11730	COG3321	synthase
E0718_RS11730	COG0604	alcohol dehydrogenase
E0718_RS11730	COG1028	Short-chain dehydrogenase reductase Sdr
E0718_RS11745	COG0300	oxidoreductase activity
E0718_RS11765	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
E0718_RS11780	COG0438	transferase activity, transferring glycosyl groups
E0718_RS11800	COG0463	Glycosyl transferase, family 2
E0718_RS11815	COG0783	Belongs to the Dps family
E0718_RS11830	COG0583	DNA-binding transcription factor activity
E0718_RS11835	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
E0718_RS11850	COG0656	L-ascorbic acid biosynthetic process
E0718_RS11855	COG2814	Major facilitator Superfamily
E0718_RS11860	COG0583	DNA-binding transcription factor activity
E0718_RS11870	COG1840	ABC-type Fe3 transport system, periplasmic component
E0718_RS11880	COG3842	ATPase activity
E0718_RS11885	COG1741	Belongs to the pirin family
E0718_RS11890	COG1741	Belongs to the pirin family
E0718_RS11895	COG0583	DNA-binding transcription factor activity
E0718_RS11900	COG2204	response regulator
E0718_RS11910	COG0174	glutamine synthetase
E0718_RS11915	COG0635	Involved in the biosynthesis of porphyrin-containing compound
E0718_RS11925	COG5001	Diguanylate cyclase
E0718_RS11925	COG5002	protein histidine kinase activity
E0718_RS11970	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
E0718_RS11975	COG0791	NLP P60 protein
E0718_RS11980	COG1028	Short-chain dehydrogenase reductase Sdr
E0718_RS11985	COG2863	cytochrome
E0718_RS11990	COG3258	Cytochrome c
E0718_RS11995	COG0194	GDP metabolic process
E0718_RS12000	COG1758	RNA polymerase activity
E0718_RS12005	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
E0718_RS12010	COG1126	abc transporter atp-binding protein
E0718_RS12015	COG0765	amino acid transport
E0718_RS12020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E0718_RS12040	COG0583	DNA-binding transcription factor activity
E0718_RS12065	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
E0718_RS12080	COG2831	hemolysin activation secretion protein
E0718_RS12085	COG3539	Fimbrial protein
E0718_RS12090	COG3188	usher protein
E0718_RS12095	COG3121	Chaperone
E0718_RS12105	COG3210	domain, Protein
E0718_RS12105	COG3064	Membrane
E0718_RS12105	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
E0718_RS12110	COG2197	response regulator
E0718_RS12165	COG4181	ATPase activity
E0718_RS12175	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
E0718_RS12180	COG0584	glycerophosphoryl diester phosphodiesterase
E0718_RS12185	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
E0718_RS12195	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
E0718_RS12195	COG0678	peroxiredoxin activity
E0718_RS12205	COG0789	Transcriptional regulator
E0718_RS12245	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
E0718_RS12255	COG2252	PERMEase
E0718_RS12260	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E0718_RS12265	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
E0718_RS12295	COG0488	(ABC) transporter
E0718_RS12300	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
E0718_RS12310	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
E0718_RS12315	COG1024	Enoyl-CoA hydratase
E0718_RS12320	COG1619	proteins homologs of microcin C7 resistance protein MccF
E0718_RS12325	COG0590	tRNA wobble adenosine to inosine editing
E0718_RS12345	COG2212	antiporter activity
E0718_RS12350	COG1863	multisubunit Na H antiporter MnhE subunit
E0718_RS12355	COG0651	ATP synthesis coupled electron transport
E0718_RS12360	COG1006	Multisubunit Na H antiporter MnhC subunit
E0718_RS12365	COG2111	Na H antiporter
E0718_RS12365	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
E0718_RS12380	COG0420	3'-5' exonuclease activity
E0718_RS12415	COG0395	ABC-type sugar transport system, permease component
E0718_RS12425	COG3842	ATPase activity
E0718_RS12455	COG3181	Tripartite tricarboxylate transporter family receptor
E0718_RS12460	COG3976	FMN-binding domain protein
E0718_RS12460	COG1053	succinate dehydrogenase
E0718_RS12490	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
E0718_RS12520	COG0450	alkyl hydroperoxide reductase
E0718_RS12525	COG1960	acyl-CoA dehydrogenase activity
E0718_RS12540	COG0123	including yeast histone deacetylase and acetoin utilization protein
E0718_RS12545	COG2951	lytic endotransglycosylase activity
E0718_RS12565	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
E0718_RS12570	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
E0718_RS12600	COG0287	Prephenate dehydrogenase
E0718_RS12635	COG2814	Major facilitator Superfamily
E0718_RS12705	COG0583	DNA-binding transcription factor activity
E0718_RS12720	COG0179	Fumarylacetoacetate (FAA) hydrolase
E0718_RS12745	COG1053	succinate dehydrogenase
E0718_RS12750	COG1012	belongs to the aldehyde dehydrogenase family
E0718_RS12755	COG2079	MmgE PrpD family protein
E0718_RS12765	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
E0718_RS12790	COG0028	Belongs to the TPP enzyme family
E0718_RS12790	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
E0718_RS12795	COG0436	Aminotransferase
E0718_RS12815	COG0778	Nitroreductase
E0718_RS12820	COG2814	Major facilitator Superfamily
E0718_RS12825	COG3706	GGDEF domain
E0718_RS12830	COG0589	response to stress
E0718_RS12840	COG2951	lytic endotransglycosylase activity
E0718_RS12845	COG2833	Protein of unknown function (DUF455)
E0718_RS12860	COG1132	(ABC) transporter
E0718_RS12870	COG1181	Belongs to the D-alanine--D-alanine ligase family
E0718_RS12870	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
E0718_RS12875	COG3237	CsbD-like
E0718_RS12885	COG2823	Periplasmic or secreted lipoprotein
E0718_RS12905	COG0672	)-iron permease
E0718_RS12920	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
E0718_RS12925	COG1028	Short-chain dehydrogenase reductase Sdr
E0718_RS12930	COG3243	poly(R)-hydroxyalkanoic acid synthase
E0718_RS12940	COG0564	pseudouridine synthase activity
E0718_RS12950	COG1199	ATP-dependent helicase activity
E0718_RS12955	COG2183	response to ionizing radiation
E0718_RS12980	COG4774	siderophore transport
E0718_RS12990	COG1595	DNA-templated transcription, initiation
E0718_RS12995	COG2175	clavaminate synthase activity
E0718_RS13005	COG3181	Tripartite tricarboxylate transporter family receptor
E0718_RS13010	COG0583	DNA-binding transcription factor activity
E0718_RS13015	COG1028	Short-chain dehydrogenase reductase Sdr
E0718_RS13020	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
E0718_RS13025	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E0718_RS13030	COG0508	dehydrogenase complex catalyzes the overall conversion of
E0718_RS13035	COG0567	Dehydrogenase, E1 component
E0718_RS13045	COG1522	sequence-specific DNA binding
E0718_RS13055	COG0280	phosphate acetyltransferase
E0718_RS13055	COG0281	malic enzyme
E0718_RS13060	COG3539	Fimbrial protein
E0718_RS13075	COG0372	Belongs to the citrate synthase family
E0718_RS13080	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
E0718_RS13085	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
E0718_RS13090	COG1053	succinate dehydrogenase
E0718_RS13095	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
E0718_RS13100	COG2009	succinate dehydrogenase
E0718_RS13105	COG2188	Transcriptional regulator
E0718_RS13110	COG0039	L-malate dehydrogenase activity
E0718_RS13130	COG2828	Protein conserved in bacteria
E0718_RS13140	COG1981	membrane
E0718_RS13165	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
E0718_RS13175	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
E0718_RS13210	COG0148	phosphopyruvate hydratase activity
E0718_RS13220	COG2877	3-deoxy-8-phosphooctulonate synthase activity
E0718_RS13225	COG0504	CTP synthase activity
E0718_RS13245	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E0718_RS13255	COG0747	negative chemotaxis
E0718_RS13260	COG4172	Belongs to the ABC transporter superfamily
E0718_RS13265	COG1446	asparaginase
E0718_RS13295	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
E0718_RS13310	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
E0718_RS13315	COG0697	spore germination
E0718_RS13320	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
E0718_RS13330	COG3193	protein, possibly involved in utilization of glycolate and propanediol
E0718_RS13335	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
E0718_RS13340	COG0791	NLP P60 protein
E0718_RS13350	COG0583	DNA-binding transcription factor activity
E0718_RS13365	COG0583	DNA-binding transcription factor activity
E0718_RS13390	COG0670	Belongs to the BI1 family
E0718_RS13395	COG3181	Tripartite tricarboxylate transporter family receptor
E0718_RS13405	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
E0718_RS13415	COG1381	Involved in DNA repair and RecF pathway recombination
E0718_RS13420	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
E0718_RS13425	COG0571	ribonuclease III activity
E0718_RS13430	COG0681	Belongs to the peptidase S26 family
E0718_RS13440	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
E0718_RS13465	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
E0718_RS13470	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
E0718_RS13495	COG0333	Belongs to the bacterial ribosomal protein bL32 family
E0718_RS13500	COG1399	metal-binding, possibly nucleic acid-binding protein
E0718_RS13515	COG3023	N-Acetylmuramoyl-L-alanine amidase
E0718_RS13525	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
E0718_RS13530	COG0546	phosphoglycolate phosphatase activity
E0718_RS13540	COG1530	ribonuclease E activity
E0718_RS13550	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
E0718_RS13555	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
E0718_RS13580	COG3228	Belongs to the MtfA family
E0718_RS13590	COG0251	oxidation-reduction process
E0718_RS13600	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
E0718_RS13615	COG2878	Part of a membrane complex involved in electron transport
E0718_RS13620	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
E0718_RS13655	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
E0718_RS13680	COG1268	BioY protein
E0718_RS13685	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
E0718_RS13690	COG1122	ATPase activity
E0718_RS13695	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
E0718_RS13705	COG0271	Belongs to the BolA IbaG family
E0718_RS13710	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
E0718_RS13725	COG1196	nuclear chromosome segregation
E0718_RS13730	COG0477	Major facilitator Superfamily
E0718_RS13735	COG1573	uracil-dna glycosylase
E0718_RS13740	COG1214	PFAM Peptidase M22, glycoprotease
E0718_RS13755	COG0450	alkyl hydroperoxide reductase
E0718_RS13760	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E0718_RS13775	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
E0718_RS13785	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
E0718_RS13790	COG0560	Phosphoserine phosphatase
E0718_RS13795	COG0583	DNA-binding transcription factor activity
E0718_RS13800	COG3181	Tripartite tricarboxylate transporter family receptor
E0718_RS13805	COG0028	Belongs to the TPP enzyme family
E0718_RS13830	COG4774	siderophore transport
E0718_RS13840	COG1007	ATP synthesis coupled electron transport
E0718_RS13855	COG0713	ATP synthesis coupled electron transport
E0718_RS13865	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E0718_RS13870	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
E0718_RS13875	COG1034	ATP synthesis coupled electron transport
E0718_RS13885	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
E0718_RS13900	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E0718_RS13905	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E0718_RS13910	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
E0718_RS13930	COG0671	phosphoesterase, PA-phosphatase related
E0718_RS13940	COG1597	lipid kinase activity
E0718_RS13945	COG0583	DNA-binding transcription factor activity
E0718_RS13950	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
E0718_RS13955	COG1733	regulation of RNA biosynthetic process
E0718_RS13960	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E0718_RS13980	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
E0718_RS14000	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
E0718_RS14020	COG3608	succinylglutamate desuccinylase aspartoacylase
E0718_RS14025	COG0626	cystathionine gamma-synthase activity
E0718_RS14030	COG0583	DNA-binding transcription factor activity
E0718_RS14040	COG3181	Tripartite tricarboxylate transporter family receptor
E0718_RS14045	COG0165	Argininosuccinate lyase
E0718_RS14060	COG3799	methylaspartate ammonia-lyase activity
E0718_RS14070	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
E0718_RS14080	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
E0718_RS14085	COG0149	triose-phosphate isomerase activity
E0718_RS14105	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
E0718_RS14115	COG1185	polyribonucleotide nucleotidyltransferase activity
E0718_RS14120	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
E0718_RS14135	COG1183	phosphatidylcholine synthase activity
E0718_RS14145	COG0440	acetolactate synthase activity
E0718_RS14150	COG0028	Belongs to the TPP enzyme family
E0718_RS14155	COG1289	transmembrane transporter activity
E0718_RS14165	COG3022	response to hydroperoxide
E0718_RS14170	COG1028	Short-chain dehydrogenase reductase Sdr
E0718_RS14185	COG3486	L-lysine 6-monooxygenase (NADPH) activity
E0718_RS14215	COG2814	Major facilitator Superfamily
E0718_RS14235	COG3706	GGDEF domain
E0718_RS14270	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
E0718_RS14280	COG1674	ftsk spoiiie
E0718_RS14285	COG0492	ferredoxin-NADP+ reductase activity
E0718_RS14290	COG1193	negative regulation of DNA recombination
E0718_RS14300	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
E0718_RS14320	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
E0718_RS14325	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
E0718_RS14330	COG2205	protein histidine kinase activity
E0718_RS14335	COG0745	RESPONSE REGULATOR receiver
E0718_RS14370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
E0718_RS14390	COG0612	Peptidase, M16
E0718_RS14410	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
E0718_RS14425	COG1420	regulation of RNA biosynthetic process
E0718_RS14435	COG0497	DNA recombination
E0718_RS14445	COG0735	belongs to the Fur family
E0718_RS14450	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E0718_RS14495	COG0446	pyridine nucleotide-disulphide oxidoreductase
E0718_RS14495	COG0404	The glycine cleavage system catalyzes the degradation of glycine
E0718_RS14500	COG4311	Sarcosine oxidase, delta subunit
E0718_RS14505	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
E0718_RS14515	COG0583	DNA-binding transcription factor activity
E0718_RS14535	COG1804	L-carnitine dehydratase bile acid-inducible protein F
E0718_RS14540	COG2030	dehydratase
E0718_RS14550	COG1024	Enoyl-CoA hydratase
E0718_RS14575	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
E0718_RS14585	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
E0718_RS14585	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
E0718_RS14600	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E0718_RS14615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
E0718_RS14625	COG0405	Gamma-glutamyltransferase
E0718_RS14640	COG1280	lysine exporter protein (LysE YggA)
E0718_RS14670	COG0583	DNA-binding transcription factor activity
E0718_RS14710	COG1414	Transcriptional regulator
E0718_RS14715	COG1546	Belongs to the CinA family
E0718_RS14715	COG1058	Belongs to the CinA family
E0718_RS14730	COG0513	Belongs to the DEAD box helicase family
E0718_RS14760	COG0429	hydrolase of the alpha beta-hydrolase fold
E0718_RS14765	COG4783	chaperone-mediated protein folding
E0718_RS14780	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
E0718_RS14795	COG0006	proline dipeptidase activity
E0718_RS14805	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E0718_RS14850	COG0514	ATP-dependent DNA helicase (RecQ)
E0718_RS14875	COG1271	oxidase subunit
E0718_RS14890	COG2894	cell division
E0718_RS14895	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
E0718_RS14910	COG0488	(ABC) transporter
E0718_RS14935	COG4608	Belongs to the ABC transporter superfamily
E0718_RS14940	COG0444	Belongs to the ABC transporter superfamily
E0718_RS14945	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E0718_RS14950	COG0601	transmembrane transport
E0718_RS14960	COG1215	transferase activity, transferring glycosyl groups
E0718_RS14975	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
E0718_RS14985	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
E0718_RS15000	COG0318	PFAM AMP-dependent synthetase and ligase
E0718_RS15005	COG2188	Transcriptional regulator
E0718_RS15010	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
E0718_RS15015	COG2814	Major facilitator Superfamily
E0718_RS15025	COG0259	pyridoxamine-phosphate oxidase activity
E0718_RS15030	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
E0718_RS15045	COG0583	DNA-binding transcription factor activity
E0718_RS15050	COG1960	acyl-CoA dehydrogenase activity
E0718_RS15060	COG1804	L-carnitine dehydratase bile acid-inducible protein F
E0718_RS15065	COG0405	Gamma-glutamyltransferase
E0718_RS15075	COG3181	Tripartite tricarboxylate transporter family receptor
E0718_RS15090	COG0802	atpase or kinase
E0718_RS15095	COG0860	N-Acetylmuramoyl-L-alanine amidase
E0718_RS15100	COG0586	Pfam SNARE associated Golgi protein
E0718_RS15130	COG0617	tRNA 3'-terminal CCA addition
E0718_RS15155	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
E0718_RS15160	COG2188	Transcriptional regulator
E0718_RS15170	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E0718_RS15175	COG1234	tRNA 3'-trailer cleavage
E0718_RS15180	COG1028	Short-chain dehydrogenase reductase Sdr
E0718_RS15190	COG1028	Short-chain dehydrogenase reductase Sdr
E0718_RS15195	COG3181	Tripartite tricarboxylate transporter family receptor
E0718_RS15200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E0718_RS15205	COG2301	Belongs to the HpcH HpaI aldolase family
E0718_RS15210	COG1804	L-carnitine dehydratase bile acid-inducible protein F
E0718_RS15215	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
E0718_RS15225	COG1024	Enoyl-CoA hydratase
E0718_RS15235	COG2188	Transcriptional regulator
E0718_RS15240	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
E0718_RS15245	COG0066	3-isopropylmalate dehydratase activity
E0718_RS15260	COG0752	glycyl-tRNA synthetase alpha subunit
E0718_RS15265	COG0751	glycine-tRNA ligase activity
E0718_RS15270	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
E0718_RS15275	COG0204	Acyl-transferase
E0718_RS15290	COG0242	peptide deformylase activity
E0718_RS15295	COG1960	acyl-CoA dehydrogenase activity
E0718_RS15300	COG0700	Nucleoside recognition
E0718_RS15305	COG0469	pyruvate kinase activity
E0718_RS15335	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
E0718_RS15345	COG2154	pterin-4-alpha-carbinolamine dehydratase
E0718_RS15365	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
E0718_RS15370	COG0154	amidase activity
E0718_RS15380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E0718_RS15390	COG0747	negative chemotaxis
E0718_RS15405	COG0019	diaminopimelate decarboxylase activity
E0718_RS15420	COG3712	iron ion homeostasis
E0718_RS15425	COG4774	siderophore transport
E0718_RS15430	COG2353	YceI-like domain
E0718_RS15435	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
E0718_RS15450	COG0583	DNA-binding transcription factor activity
E0718_RS15470	COG3384	dioxygenase
E0718_RS15475	COG0179	Fumarylacetoacetate (FAA) hydrolase
E0718_RS15510	COG1028	Short-chain dehydrogenase reductase Sdr
E0718_RS15515	COG1309	transcriptional regulator
E0718_RS15520	COG2982	Protein involved in outer membrane biogenesis
E0718_RS15525	COG2818	Glycosylase
E0718_RS15545	COG1653	transport
E0718_RS15550	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E0718_RS15555	COG3842	ATPase activity
E0718_RS15560	COG0395	ABC-type sugar transport system, permease component
E0718_RS15585	COG2186	Transcriptional regulator
E0718_RS15605	COG1454	alcohol dehydrogenase
E0718_RS15620	COG2011	ABC-type metal ion transport system permease component
E0718_RS15625	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
E0718_RS15630	COG1501	Belongs to the glycosyl hydrolase 31 family
E0718_RS15645	COG0318	PFAM AMP-dependent synthetase and ligase
E0718_RS15650	COG1473	amidohydrolase
E0718_RS15660	COG2855	membrane
E0718_RS15670	COG2239	Acts as a magnesium transporter
E0718_RS15685	COG1522	sequence-specific DNA binding
E0718_RS15690	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
E0718_RS15695	COG1028	Short-chain dehydrogenase reductase Sdr
E0718_RS15720	COG0739	heme binding
E0718_RS15730	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
E0718_RS15735	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
E0718_RS15745	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
E0718_RS15750	COG1181	Belongs to the D-alanine--D-alanine ligase family
E0718_RS15775	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
E0718_RS15780	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
E0718_RS15790	COG3116	cell division
E0718_RS15795	COG0275	rRNA processing
E0718_RS15800	COG2001	Belongs to the MraZ family
E0718_RS15810	COG0488	(ABC) transporter
E0718_RS15815	COG0418	dihydroorotase activity
E0718_RS15820	COG1473	amidohydrolase
E0718_RS15870	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
E0718_RS15875	COG4654	Cytochrome c, class I
E0718_RS15930	COG2084	Dehydrogenase
E0718_RS15975	COG0824	Thioesterase
E0718_RS15980	COG0811	peptide transport
E0718_RS15985	COG0848	biopolymer transport protein
E0718_RS16010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E0718_RS16015	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
E0718_RS16020	COG3181	Tripartite tricarboxylate transporter family receptor
E0718_RS16035	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
E0718_RS16060	COG0183	Belongs to the thiolase family
E0718_RS16070	COG1960	acyl-CoA dehydrogenase activity
E0718_RS16075	COG0583	DNA-binding transcription factor activity
E0718_RS16080	COG3181	Tripartite tricarboxylate transporter family receptor
E0718_RS16085	COG1024	Enoyl-CoA hydratase
E0718_RS16095	COG1253	flavin adenine dinucleotide binding
E0718_RS16100	COG1285	pathogenesis
E0718_RS16125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E0718_RS16130	COG0697	spore germination
E0718_RS16140	COG1073	alpha beta
E0718_RS16165	COG0463	Glycosyl transferase, family 2
E0718_RS16175	COG0786	glutamate:sodium symporter activity
E0718_RS16185	COG2031	fatty acid transporter
E0718_RS16200	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E0718_RS16205	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E0718_RS16215	COG0328	RNA-DNA hybrid ribonuclease activity
E0718_RS16220	COG2226	methyltransferase
E0718_RS16225	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E0718_RS16230	COG0741	lytic transglycosylase activity
E0718_RS16230	COG1388	LysM domain
E0718_RS16245	COG2979	Protein of unknown function (DUF533)
E0718_RS16265	COG3181	Tripartite tricarboxylate transporter family receptor
E0718_RS16280	COG3119	arylsulfatase activity
E0718_RS16305	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
E0718_RS16325	COG0832	Belongs to the urease beta subunit family
E0718_RS16335	COG0831	urea catabolic process
E0718_RS16340	COG0829	nickel cation binding
E0718_RS16355	COG0633	Ferredoxin
E0718_RS16370	COG2188	Transcriptional regulator
E0718_RS16375	COG3799	methylaspartate ammonia-lyase activity
E0718_RS16395	COG2719	SpoVR family
E0718_RS16400	COG2718	Belongs to the UPF0229 family
E0718_RS16405	COG2766	serine protein kinase
E0718_RS16410	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
E0718_RS16410	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
E0718_RS16420	COG4977	sequence-specific DNA binding
E0718_RS16425	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
E0718_RS16455	COG0316	Belongs to the HesB IscA family
E0718_RS16475	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
E0718_RS16480	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
E0718_RS16485	COG0312	modulator of DNA gyrase
E0718_RS16505	COG1116	anion transmembrane transporter activity
E0718_RS16510	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
E0718_RS16515	COG1335	isochorismatase
E0718_RS16520	COG0346	lactoylglutathione lyase activity
E0718_RS16525	COG0513	Belongs to the DEAD box helicase family
E0718_RS16535	COG1802	Transcriptional regulator
E0718_RS16540	COG1042	CoA-binding domain protein
E0718_RS16540	COG0045	succinate-CoA ligase (ADP-forming) activity
E0718_RS16540	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E0718_RS16560	COG1522	sequence-specific DNA binding
E0718_RS16590	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
E0718_RS16595	COG1696	Membrane protein involved in D-alanine export
E0718_RS16620	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E0718_RS16635	COG0439	Biotin carboxylase
E0718_RS16640	COG0511	ligase activity, forming carbon-carbon bonds
E0718_RS16645	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
E0718_RS16650	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
E0718_RS16655	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
E0718_RS16660	COG3150	esterase
E0718_RS16665	COG0557	exoribonuclease II activity
E0718_RS16680	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
E0718_RS16715	COG1678	Uncharacterized ACR, COG1678
E0718_RS16730	COG0352	thiamine-phosphate diphosphorylase activity
E0718_RS16760	COG1960	acyl-CoA dehydrogenase activity
E0718_RS16770	COG1028	Short-chain dehydrogenase reductase Sdr
E0718_RS16830	COG0494	nUDIX hydrolase
E0718_RS16855	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
E0718_RS16880	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
E0718_RS16885	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
E0718_RS16915	COG1126	abc transporter atp-binding protein
E0718_RS16920	COG0765	amino acid transport
E0718_RS16925	COG4597	amino acid ABC transporter
E0718_RS16930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E0718_RS16935	COG2884	Cell division ATP-binding protein ftsE
E0718_RS16940	COG2177	Part of the ABC transporter FtsEX involved in
E0718_RS16955	COG1194	a g-specific adenine glycosylase
E0718_RS16975	COG4206	TonB-dependent receptor
E0718_RS16980	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
E0718_RS16990	COG0351	phosphomethylpyrimidine kinase
E0718_RS16995	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
E0718_RS17005	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
E0718_RS17015	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
E0718_RS17030	COG2226	methyltransferase
E0718_RS17035	COG0745	RESPONSE REGULATOR receiver
E0718_RS17040	COG5002	protein histidine kinase activity
E0718_RS17050	COG5002	protein histidine kinase activity
E0718_RS17060	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
E0718_RS17065	COG0583	DNA-binding transcription factor activity
E0718_RS17075	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
E0718_RS17080	COG1984	allophanate hydrolase subunit 2
E0718_RS17095	COG3181	Tripartite tricarboxylate transporter family receptor
E0718_RS17105	COG1024	Enoyl-CoA hydratase
E0718_RS17120	COG1802	Transcriptional regulator
E0718_RS17130	COG1238	metal cluster binding
E0718_RS17135	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
E0718_RS17140	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
E0718_RS17160	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
E0718_RS17165	COG4988	ABC transporter
E0718_RS17175	COG1294	oxidase, subunit
E0718_RS17200	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
E0718_RS17215	COG1137	ATPase activity
E0718_RS17220	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
E0718_RS17235	COG1529	Aldehyde oxidase and xanthine dehydrogenase
E0718_RS17235	COG2010	Cytochrome c
E0718_RS17245	COG1660	Displays ATPase and GTPase activities
E0718_RS17255	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
E0718_RS17270	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
E0718_RS17275	COG2823	Periplasmic or secreted lipoprotein
E0718_RS17305	COG0471	metal ion transport
E0718_RS17310	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
E0718_RS17315	COG0772	Belongs to the SEDS family
E0718_RS17320	COG0768	penicillin binding
E0718_RS17330	COG1792	Involved in formation and maintenance of cell shape
E0718_RS17335	COG1077	Cell shape determining protein MreB Mrl
E0718_RS17360	COG0708	Exodeoxyribonuclease III
E0718_RS17370	COG2860	membrane
E0718_RS17380	COG0583	DNA-binding transcription factor activity
E0718_RS17385	COG0473	3-isopropylmalate dehydrogenase activity
E0718_RS17410	COG0583	DNA-binding transcription factor activity
E0718_RS17415	COG2515	1-aminocyclopropane-1-carboxylate deaminase
E0718_RS17420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E0718_RS17425	COG0765	amino acid transport
E0718_RS17430	COG0765	amino acid transport
E0718_RS17435	COG1126	abc transporter atp-binding protein
E0718_RS17440	COG1794	racemase activity, acting on amino acids and derivatives
E0718_RS17445	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
E0718_RS17450	COG2223	nitrite transmembrane transporter activity
E0718_RS17455	COG2813	Specifically methylates the guanine in position
E0718_RS17455	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
E0718_RS17465	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
E0718_RS17510	COG0583	DNA-binding transcription factor activity
E0718_RS17515	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
E0718_RS17520	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
E0718_RS17555	COG0154	amidase activity
E0718_RS17565	COG1414	Transcriptional regulator
E0718_RS17575	COG1250	3-hydroxyacyl-CoA dehydrogenase
E0718_RS17575	COG1024	Enoyl-CoA hydratase
E0718_RS17585	COG2132	Multicopper oxidase
E0718_RS17630	COG1024	Enoyl-CoA hydratase
E0718_RS17635	COG1024	Enoyl-CoA hydratase
E0718_RS17640	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
E0718_RS17650	COG0747	negative chemotaxis
E0718_RS17660	COG0601	transmembrane transport
E0718_RS17665	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E0718_RS17670	COG0444	Belongs to the ABC transporter superfamily
E0718_RS17675	COG4608	Belongs to the ABC transporter superfamily
E0718_RS17685	COG2195	Cleaves the N-terminal amino acid of tripeptides
E0718_RS17690	COG0210	DNA helicase
E0718_RS17695	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
E0718_RS17710	COG0355	proton-transporting ATP synthase activity, rotational mechanism
E0718_RS17730	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
E0718_RS17745	COG0356	it plays a direct role in the translocation of protons across the membrane
E0718_RS17760	COG1024	Enoyl-CoA hydratase
E0718_RS17785	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
E0718_RS17795	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E0718_RS17800	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
E0718_RS17805	COG2967	ApaG domain
E0718_RS17810	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
E0718_RS17815	COG0546	phosphoglycolate phosphatase activity
E0718_RS17825	COG0512	Glutamine amidotransferase of anthranilate synthase
E0718_RS17840	COG1028	Short-chain dehydrogenase reductase Sdr
E0718_RS17860	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E0718_RS17870	COG1607	acyl-coa hydrolase
E0718_RS17925	COG1802	Transcriptional regulator
E0718_RS17955	COG1595	DNA-templated transcription, initiation
E0718_RS17970	COG3720	iron ion transport
E0718_RS17975	COG4558	Periplasmic binding protein
E0718_RS17980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E0718_RS17990	COG1683	Conserved Protein
E0718_RS18020	COG3064	Membrane
E0718_RS18025	COG0583	DNA-binding transcription factor activity
E0718_RS18035	COG1234	tRNA 3'-trailer cleavage
E0718_RS18045	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
E0718_RS18050	COG1802	Transcriptional regulator
E0718_RS18060	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
E0718_RS18080	COG1804	L-carnitine dehydratase bile acid-inducible protein F
E0718_RS18100	COG3181	Tripartite tricarboxylate transporter family receptor
E0718_RS18105	COG0583	DNA-binding transcription factor activity
E0718_RS18115	COG1522	sequence-specific DNA binding
E0718_RS18120	COG0183	Belongs to the thiolase family
E0718_RS18180	COG2814	Major facilitator Superfamily
E0718_RS18205	COG1999	signal sequence binding
E0718_RS18250	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
E0718_RS18270	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
E0718_RS18280	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
E0718_RS18290	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
E0718_RS18295	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
E0718_RS18305	COG0067	glutamate synthase
E0718_RS18305	COG0069	glutamate synthase activity
E0718_RS18305	COG0070	glutamate synthase
E0718_RS18315	COG3047	cAMP biosynthetic process
E0718_RS18325	COG1127	ABC transporter
E0718_RS18330	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
E0718_RS18335	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
E0718_RS18340	COG2853	Lipoprotein
E0718_RS18350	COG1131	(ABC) transporter
E0718_RS18355	COG0842	Transport permease protein
E0718_RS18375	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
E0718_RS18385	COG0131	Imidazoleglycerol-phosphate dehydratase
E0718_RS18395	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
E0718_RS18410	COG0140	phosphoribosyl-ATP diphosphatase activity
E0718_RS18415	COG0537	adenosine 5'-monophosphoramidase activity
E0718_RS18420	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
E0718_RS18445	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
E0718_RS18455	COG0723	plastoquinol--plastocyanin reductase activity
E0718_RS18460	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
E0718_RS18465	COG2857	Cytochrome c1
E0718_RS18470	COG0625	glutathione transferase activity
E0718_RS18475	COG2969	positive regulation of protein catabolic process
E0718_RS18505	COG0583	DNA-binding transcription factor activity
E0718_RS18510	COG0492	ferredoxin-NADP+ reductase activity
E0718_RS18530	COG1804	L-carnitine dehydratase bile acid-inducible protein F
E0718_RS18540	COG1804	L-carnitine dehydratase bile acid-inducible protein F
E0718_RS18555	COG3181	Tripartite tricarboxylate transporter family receptor
E0718_RS18590	COG3702	type iv secretory pathway
E0718_RS18610	COG3736	Type IV secretory pathway, component VirB8
E0718_RS18625	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
E0718_RS18635	COG0697	spore germination
E0718_RS18655	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
E0718_RS18660	COG0747	negative chemotaxis
E0718_RS18665	COG0601	transmembrane transport
E0718_RS18670	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E0718_RS18680	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
E0718_RS18690	COG0513	Belongs to the DEAD box helicase family
E0718_RS18695	COG1280	lysine exporter protein (LysE YggA)
E0718_RS18720	COG0583	DNA-binding transcription factor activity
E0718_RS18730	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
E0718_RS18740	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
E0718_RS18745	COG0154	amidase activity
E0718_RS18750	COG1609	Transcriptional regulator
E0718_RS18770	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
E0718_RS18775	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
E0718_RS18780	COG3842	ATPase activity
E0718_RS18785	COG1653	transport
E0718_RS18790	COG1175	transmembrane transport
E0718_RS18795	COG0395	ABC-type sugar transport system, permease component
E0718_RS18830	COG1280	lysine exporter protein (LysE YggA)
E0718_RS18845	COG1960	acyl-CoA dehydrogenase activity
E0718_RS18855	COG0183	Belongs to the thiolase family
E0718_RS18860	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
E0718_RS18880	COG3181	Tripartite tricarboxylate transporter family receptor
E0718_RS18890	COG2358	TRAP transporter, solute receptor (TAXI family
E0718_RS18905	COG2922	Belongs to the Smg family
E0718_RS18930	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
E0718_RS18935	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
E0718_RS18940	COG1028	Short-chain dehydrogenase reductase Sdr
E0718_RS18945	COG1012	belongs to the aldehyde dehydrogenase family
E0718_RS18955	COG0028	Belongs to the TPP enzyme family
E0718_RS18960	COG1522	sequence-specific DNA binding
E0718_RS18965	COG3781	membrane
E0718_RS18995	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
E0718_RS19020	COG1304	FMN binding
E0718_RS19040	COG1414	Transcriptional regulator
E0718_RS19055	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
E0718_RS19060	COG0230	Belongs to the bacterial ribosomal protein bL34 family
E0718_RS19065	COG0594	ribonuclease P activity
E0718_RS19070	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
E0718_RS19080	COG0753	catalase activity
E0718_RS19085	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
E0718_RS19090	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
E0718_RS19100	COG2175	clavaminate synthase activity
E0718_RS19105	COG1473	amidohydrolase
E0718_RS19110	COG4608	Belongs to the ABC transporter superfamily
E0718_RS19115	COG0444	Belongs to the ABC transporter superfamily
E0718_RS19125	COG0601	transmembrane transport
E0718_RS19130	COG0747	negative chemotaxis
E0718_RS19170	COG0436	Aminotransferase
E0718_RS19175	COG1278	Cold shock
E0718_RS19185	COG0357	Ribosomal RNA small subunit methyltransferase G
E0718_RS19190	COG1192	Involved in chromosome partitioning
E0718_RS19200	COG1475	DNA binding
E0718_RS19205	COG0252	asparaginase activity
E0718_RS19225	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
E0718_RS19235	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
E0718_RS19250	COG0081	regulation of translation
E0718_RS19255	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
E0718_RS19260	COG0222	ribosome binding
E0718_RS19270	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
E0718_RS19305	COG1230	cation diffusion facilitator family transporter
E0718_RS19315	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
E0718_RS19320	COG0049	tRNA binding
E0718_RS19330	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
E0718_RS19340	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
E0718_RS19350	COG0089	rRNA binding
E0718_RS19355	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
E0718_RS19365	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
E0718_RS19370	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
E0718_RS19375	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
E0718_RS19380	COG0255	Belongs to the universal ribosomal protein uL29 family
E0718_RS19385	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
E0718_RS19405	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
E0718_RS19410	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
E0718_RS19415	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
E0718_RS19420	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
E0718_RS19425	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
E0718_RS19435	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
E0718_RS19440	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
E0718_RS19445	COG1841	ribosomal large subunit assembly
E0718_RS19455	COG0201	protein transport
E0718_RS19460	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
E0718_RS19465	COG0257	Belongs to the bacterial ribosomal protein bL36 family
E0718_RS19470	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
E0718_RS19475	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
E0718_RS19480	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
E0718_RS19485	COG0202	RNA polymerase activity
E0718_RS19490	COG0203	ribosomal protein L17
E0718_RS19495	COG0537	adenosine 5'-monophosphoramidase activity
E0718_RS19500	COG1324	tolerance protein
E0718_RS19505	COG4232	protein-disulfide reductase activity
E0718_RS19520	COG0218	Necessary for normal cell division and for the maintenance of normal septation
E0718_RS19530	COG1333	cytochrome c biogenesis protein
E0718_RS19535	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E0718_RS19560	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
E0718_RS19565	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
E0718_RS19585	COG2814	Major facilitator Superfamily
E0718_RS19630	COG0402	S-adenosylhomocysteine deaminase activity
E0718_RS19640	COG0438	transferase activity, transferring glycosyl groups
E0718_RS19660	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
E0718_RS19690	COG2186	Transcriptional regulator
E0718_RS19710	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E0718_RS19715	COG1956	GAF domain-containing protein
E0718_RS19720	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
E0718_RS19750	COG0531	amino acid
E0718_RS19780	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
E0718_RS19785	COG3568	Endonuclease Exonuclease Phosphatase
E0718_RS19790	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
E0718_RS19810	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E0718_RS19820	COG0367	asparagine synthase
E0718_RS19840	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
E0718_RS19845	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
E0718_RS19885	COG0367	asparagine synthase
E0718_RS19890	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
E0718_RS19915	COG0367	asparagine synthase
E0718_RS19925	COG0438	transferase activity, transferring glycosyl groups
E0718_RS19945	COG0438	transferase activity, transferring glycosyl groups
E0718_RS19950	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
E0718_RS19955	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
E0718_RS19985	COG0859	PFAM glycosyl transferase family 9
E0718_RS20015	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
E0718_RS20020	COG1127	ABC transporter
E0718_RS20040	COG1686	Belongs to the peptidase S11 family
E0718_RS20080	COG2096	Adenosyltransferase
E0718_RS20105	COG0523	cobalamin synthesis protein
E0718_RS20110	COG0735	belongs to the Fur family
E0718_RS20115	COG1121	(ABC) transporter
E0718_RS20125	COG0803	Belongs to the bacterial solute-binding protein 9 family
E0718_RS20135	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
E0718_RS20145	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
E0718_RS20155	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
E0718_RS20160	COG1560	Kdo2-lipid A biosynthetic process
E0718_RS20170	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
E0718_RS20190	COG1950	PFAM Membrane protein of
E0718_RS20200	COG0583	DNA-binding transcription factor activity
E0718_RS20210	COG0477	Major facilitator Superfamily
E0718_RS20235	COG0513	Belongs to the DEAD box helicase family
E0718_RS20245	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E0718_RS20250	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
E0718_RS20265	COG0735	belongs to the Fur family
E0718_RS20285	COG0438	transferase activity, transferring glycosyl groups
E0718_RS20310	COG0640	Transcriptional regulator
E0718_RS20370	COG0583	DNA-binding transcription factor activity
E0718_RS20385	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
E0718_RS20390	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E0718_RS20395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E0718_RS20410	COG0758	DNA mediated transformation
E0718_RS20415	COG1522	sequence-specific DNA binding
E0718_RS20425	COG0242	peptide deformylase activity
E0718_RS20440	COG0546	phosphoglycolate phosphatase activity
E0718_RS20460	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
E0718_RS20465	COG1942	4-Oxalocrotonate Tautomerase
E0718_RS20470	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
E0718_RS20505	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
E0718_RS20505	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
E0718_RS20515	COG5000	phosphorelay sensor kinase activity
E0718_RS20520	COG2204	response regulator
E0718_RS20545	COG2068	MobA-Related Protein
E0718_RS20560	COG0596	Alpha beta hydrolase
E0718_RS20565	COG2309	aminopeptidase activity
E0718_RS20570	COG1335	isochorismatase
E0718_RS20595	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
E0718_RS20620	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
E0718_RS20625	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
E0718_RS20645	COG2226	methyltransferase
E0718_RS20660	COG3181	Tripartite tricarboxylate transporter family receptor
E0718_RS20670	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
E0718_RS20675	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
E0718_RS20680	COG1054	Belongs to the UPF0176 family
E0718_RS20690	COG4942	peptidase
E0718_RS20695	COG0793	Belongs to the peptidase S41A family
E0718_RS20700	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
E0718_RS20720	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
E0718_RS20755	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
E0718_RS20760	COG0211	Belongs to the bacterial ribosomal protein bL27 family
E0718_RS20765	COG0261	This protein binds to 23S rRNA in the presence of protein L20
E0718_RS20775	COG0142	geranyltranstransferase activity
E0718_RS20785	COG0583	DNA-binding transcription factor activity
E0718_RS20795	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
E0718_RS20800	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
E0718_RS20815	COG2994	toxin metabolic process
E0718_RS20825	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
E0718_RS20830	COG2274	protein secretion by the type I secretion system
E0718_RS20835	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E0718_RS20840	COG1538	Outer membrane efflux protein
E0718_RS20855	COG0765	amino acid transport
E0718_RS20860	COG0765	amino acid transport
E0718_RS20865	COG1126	abc transporter atp-binding protein
E0718_RS20885	COG1028	Short-chain dehydrogenase reductase Sdr
E0718_RS20895	COG1802	Transcriptional regulator
E0718_RS20910	COG1802	Transcriptional regulator
E0718_RS20920	COG0318	PFAM AMP-dependent synthetase and ligase
E0718_RS20930	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
E0718_RS20960	COG0583	DNA-binding transcription factor activity
E0718_RS20965	COG1804	L-carnitine dehydratase bile acid-inducible protein F
E0718_RS20970	COG2301	Belongs to the HpcH HpaI aldolase family
E0718_RS20975	COG2188	Transcriptional regulator
E0718_RS21020	COG0583	DNA-binding transcription factor activity
E0718_RS21025	COG1024	Enoyl-CoA hydratase
E0718_RS21060	COG1028	Short-chain dehydrogenase reductase Sdr
E0718_RS21075	COG1902	pentaerythritol trinitrate reductase activity
E0718_RS21100	COG0745	RESPONSE REGULATOR receiver
E0718_RS21140	COG2890	protein-(glutamine-N5) methyltransferase activity
E0718_RS21145	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
E0718_RS21155	COG3181	Tripartite tricarboxylate transporter family receptor
E0718_RS21225	COG4211	Belongs to the binding-protein-dependent transport system permease family
E0718_RS21235	COG0683	leucine binding
E0718_RS21240	COG0154	amidase activity
E0718_RS21245	COG0288	reversible hydration of carbon dioxide
E0718_RS21265	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
E0718_RS21280	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
E0718_RS21290	COG1414	Transcriptional regulator
E0718_RS21295	COG1028	Short-chain dehydrogenase reductase Sdr
E0718_RS21300	COG2031	fatty acid transporter
E0718_RS21305	COG1250	3-hydroxyacyl-CoA dehydrogenase
E0718_RS21340	COG2808	Putative FMN-binding domain
E0718_RS21345	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
E0718_RS21350	COG0747	negative chemotaxis
E0718_RS21355	COG0657	acetylesterase activity
E0718_RS21365	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
E0718_RS21370	COG2207	Transcriptional regulator
E0718_RS21395	COG1538	Outer membrane efflux protein
E0718_RS21410	COG0583	DNA-binding transcription factor activity
E0718_RS21415	COG0628	permease
E0718_RS21425	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
E0718_RS21430	COG0251	oxidation-reduction process
E0718_RS21440	COG0330	HflC and HflK could
E0718_RS21445	COG3422	double-strand break repair
E0718_RS21460	COG0583	DNA-binding transcription factor activity
E0718_RS21495	COG3181	Tripartite tricarboxylate transporter family receptor
E0718_RS21500	COG0318	PFAM AMP-dependent synthetase and ligase
E0718_RS21505	COG1414	Transcriptional regulator
E0718_RS21510	COG1024	Enoyl-CoA hydratase
E0718_RS21515	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E0718_RS21520	COG3181	Tripartite tricarboxylate transporter family receptor
E0718_RS21525	COG0604	alcohol dehydrogenase
E0718_RS21530	COG1804	L-carnitine dehydratase bile acid-inducible protein F
E0718_RS21535	COG0583	DNA-binding transcription factor activity
E0718_RS21545	COG1804	L-carnitine dehydratase bile acid-inducible protein F
E0718_RS21560	COG0251	oxidation-reduction process
E0718_RS21570	COG2031	fatty acid transporter
E0718_RS21600	COG1278	Cold shock
E0718_RS21605	COG0583	DNA-binding transcription factor activity
E0718_RS21615	COG3119	arylsulfatase activity
E0718_RS21630	COG1228	amidohydrolase
E0718_RS21635	COG0523	cobalamin synthesis protein
E0718_RS21640	COG1819	glycosyl
E0718_RS21725	COG0625	glutathione transferase activity
E0718_RS21740	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E0718_RS21745	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
E0718_RS21750	COG1652	LysM domain
E0718_RS21775	COG1804	L-carnitine dehydratase bile acid-inducible protein F
E0718_RS21780	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
E0718_RS21815	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
E0718_RS21870	COG0583	DNA-binding transcription factor activity
E0718_RS21875	COG3181	Tripartite tricarboxylate transporter family receptor
E0718_RS21885	COG1024	Enoyl-CoA hydratase
E0718_RS21890	COG3181	Tripartite tricarboxylate transporter family receptor
E0718_RS21915	COG0028	Belongs to the TPP enzyme family
E0718_RS21925	COG1024	Enoyl-CoA hydratase
E0718_RS21925	COG1250	3-hydroxyacyl-CoA dehydrogenase
E0718_RS21930	COG3181	Tripartite tricarboxylate transporter family receptor
E0718_RS21935	COG1414	Transcriptional regulator
E0718_RS21955	COG0318	PFAM AMP-dependent synthetase and ligase
E0718_RS21960	COG1609	Transcriptional regulator
E0718_RS21990	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E0718_RS21995	COG1024	Enoyl-CoA hydratase
E0718_RS22010	COG1804	L-carnitine dehydratase bile acid-inducible protein F
E0718_RS22015	COG3181	Tripartite tricarboxylate transporter family receptor
E0718_RS22020	COG0583	DNA-binding transcription factor activity
E0718_RS22035	COG1960	acyl-CoA dehydrogenase activity
E0718_RS22050	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
E0718_RS22060	COG1053	succinate dehydrogenase
E0718_RS22060	COG3976	FMN-binding domain protein
E0718_RS22095	COG0683	leucine binding
E0718_RS22105	COG1309	transcriptional regulator
E0718_RS22125	COG1028	Short-chain dehydrogenase reductase Sdr
E0718_RS22130	COG1960	acyl-CoA dehydrogenase activity
E0718_RS22135	COG1028	Short-chain dehydrogenase reductase Sdr
E0718_RS22140	COG0318	PFAM AMP-dependent synthetase and ligase
E0718_RS22150	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
E0718_RS22160	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
E0718_RS22165	COG1053	succinate dehydrogenase
E0718_RS22175	COG2030	dehydratase
E0718_RS22185	COG1804	L-carnitine dehydratase bile acid-inducible protein F
E0718_RS22190	COG1804	L-carnitine dehydratase bile acid-inducible protein F
E0718_RS22195	COG3181	Tripartite tricarboxylate transporter family receptor
E0718_RS22220	COG0559	Belongs to the binding-protein-dependent transport system permease family
E0718_RS22240	COG0446	pyridine nucleotide-disulphide oxidoreductase
E0718_RS22240	COG1902	pentaerythritol trinitrate reductase activity
E0718_RS22255	COG0427	acetyl-CoA hydrolase
E0718_RS22260	COG0318	PFAM AMP-dependent synthetase and ligase
E0718_RS22275	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
E0718_RS22295	COG0183	Belongs to the thiolase family
E0718_RS22300	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
E0718_RS22310	COG1804	L-carnitine dehydratase bile acid-inducible protein F
E0718_RS22315	COG0583	DNA-binding transcription factor activity
E0718_RS22320	COG1960	acyl-CoA dehydrogenase activity
E0718_RS22335	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
E0718_RS22360	COG1309	transcriptional regulator
E0718_RS22370	COG1024	Enoyl-CoA hydratase
E0718_RS22390	COG1024	Enoyl-CoA hydratase
E0718_RS22395	COG1804	L-carnitine dehydratase bile acid-inducible protein F
E0718_RS22400	COG3181	Tripartite tricarboxylate transporter family receptor
E0718_RS22405	COG1454	alcohol dehydrogenase
E0718_RS22410	COG1024	Enoyl-CoA hydratase
E0718_RS22430	COG1012	belongs to the aldehyde dehydrogenase family
E0718_RS22435	COG0431	NADPH-dependent FMN reductase
E0718_RS22440	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
E0718_RS22445	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
E0718_RS22460	COG1414	Transcriptional regulator
E0718_RS22465	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
E0718_RS22470	COG1028	Short-chain dehydrogenase reductase Sdr
E0718_RS22475	COG3181	Tripartite tricarboxylate transporter family receptor
E0718_RS22500	COG0318	PFAM AMP-dependent synthetase and ligase
E0718_RS22520	COG1024	Enoyl-CoA hydratase
E0718_RS22530	COG1960	acyl-CoA dehydrogenase activity
E0718_RS22535	COG1024	Enoyl-CoA hydratase
E0718_RS22540	COG0183	Belongs to the thiolase family