locus-tag class description FYB61_RS00010 ENOG4105D28 Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity) FYB61_RS00015 ENOG4107QJE Chromosome Partitioning Protein FYB61_RS00025 ENOG4105FA0 parb-like partition protein FYB61_RS00030 ENOG4105HDK L-asparaginase FYB61_RS00050 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) FYB61_RS00060 ENOG410683Z Preprotein translocase SecE subunit FYB61_RS00075 ENOG4105C64 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity) FYB61_RS00080 ENOG4108VZM 50s ribosomal protein L10 FYB61_RS00085 ENOG4105KBC Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity) FYB61_RS00095 ENOG4107QR0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) FYB61_RS00130 ENOG4105PGM cation diffusion facilitator family transporter FYB61_RS00140 ENOG4108UKE Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity) FYB61_RS00145 ENOG4108UHY One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity) FYB61_RS00155 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) FYB61_RS00165 ENOG4105EEE One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity) FYB61_RS00175 ENOG41080KG One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) FYB61_RS00180 ENOG4105CFD One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity FYB61_RS00190 ENOG4105KAP The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity) FYB61_RS00195 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) FYB61_RS00200 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) FYB61_RS00205 ENOG41084PQ 50s ribosomal protein l29 FYB61_RS00210 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal FYB61_RS00230 ENOG4108UNN Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity) FYB61_RS00235 ENOG4105KAR One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity) FYB61_RS00240 ENOG4105CW6 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits FYB61_RS00245 ENOG4105VBI Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity) FYB61_RS00250 ENOG4108UJY One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity) FYB61_RS00260 ENOG4105K4C This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity) FYB61_RS00265 ENOG4108RA9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity) FYB61_RS00270 ENOG4105VPB 50S ribosomal protein L30 FYB61_RS00280 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) FYB61_RS00285 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) FYB61_RS00295 ENOG4108Z04 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits FYB61_RS00300 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) FYB61_RS00305 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) FYB61_RS00310 ENOG4105CTF DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) FYB61_RS00315 ENOG4108ZT0 50S ribosomal protein l17 FYB61_RS00320 ENOG4107YU2 histidine triad (hIT) protein FYB61_RS00325 ENOG4105VF7 tolerance protein FYB61_RS00330 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) FYB61_RS00340 ENOG4105D52 delta-aminolevulinic acid dehydratase FYB61_RS00345 ENOG4105WHM Necessary for normal cell division and for the maintenance of normal septation (By similarity) FYB61_RS00350 ENOG4106RE7 Cytochrome FYB61_RS00355 ENOG4105EBH Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity) FYB61_RS00360 ENOG4105CRE cytochrome C FYB61_RS00365 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) FYB61_RS00375 ENOG4108JQC penicillin-binding protein 1A FYB61_RS00380 ENOG4105KHV Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity) FYB61_RS00385 ENOG4105D49 3-dehydroquinate synthase FYB61_RS00400 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) FYB61_RS00405 ENOG4107RDB Major Facilitator FYB61_RS00455 ENOG4105JN3 extra-cytoplasmic solute receptor family protein FYB61_RS00460 ENOG4105JNK Glycosyl transferase (Group 1 FYB61_RS00480 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component FYB61_RS00510 ENOG4108KWP DNA-binding transcriptional regulator GlcC FYB61_RS00530 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FYB61_RS00535 ENOG4108ZGC gaf domain protein FYB61_RS00540 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) FYB61_RS00570 ENOG4107R7I amino acid FYB61_RS00600 ENOG4105C9M aspartyl-trna synthetase FYB61_RS00605 ENOG4105X23 Endonuclease Exonuclease phosphatase FYB61_RS00610 ENOG4105DZQ phospholipase D Transphosphatidylase FYB61_RS00630 ENOG4105C1B dTDP-glucose 4-6-dehydratase FYB61_RS00635 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase FYB61_RS00640 ENOG4105CAQ asparagine synthetase FYB61_RS00645 ENOG4105CAE Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity) FYB61_RS00660 ENOG4105CAE Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity) FYB61_RS00665 ENOG4105CAE Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity) FYB61_RS00680 ENOG4105EY8 ABC transporter FYB61_RS00685 ENOG4105EY8 ABC transporter FYB61_RS00705 ENOG4105CAQ asparagine synthetase FYB61_RS00720 ENOG4105C1B dTDP-glucose 4-6-dehydratase FYB61_RS00735 ENOG4105CAQ asparagine synthetase FYB61_RS00745 ENOG4105CG5 Glycosyl transferase (Group 1 FYB61_RS00765 ENOG4107UU3 sucrose-phosphate synthase (EC 2.4.1.14) FYB61_RS00770 ENOG4105D3Q Sugar transferase FYB61_RS00775 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase FYB61_RS00785 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase FYB61_RS00790 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase FYB61_RS00795 ENOG4105J5G Transferase hexapeptide repeat containing protein FYB61_RS00805 ENOG4105D16 lipopolysaccharide heptosyltransferase i FYB61_RS00810 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase FYB61_RS00835 ENOG4105DHJ ABC, transporter FYB61_RS00855 ENOG4105DZ1 carboxypeptidase FYB61_RS00860 ENOG4105F0I Aminotransferase FYB61_RS00880 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase FYB61_RS00895 ENOG4108WBT adenosyltransferase FYB61_RS00920 ENOG4105CKI cobalamin synthesis protein FYB61_RS00925 ENOG4105MYN Zinc uptake regulation protein FYB61_RS00935 ENOG4105DIK (ABC) transporter FYB61_RS00940 ENOG4105CC5 ABC transporter FYB61_RS00945 ENOG4105DSE periplasmic solute binding protein FYB61_RS00955 ENOG4105D7X high-affinity nickel-transporter FYB61_RS00960 ENOG4105UGU tonB-dependent Receptor FYB61_RS00965 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FYB61_RS00975 ENOG4105E4Z Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity) FYB61_RS00980 ENOG4105D1S lipid A biosynthesis FYB61_RS00990 ENOG4105CPH Catalyzes the formation of S-adenosylmethionine from methionine and ATP FYB61_RS01000 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) FYB61_RS01010 ENOG41086DT Membrane protein of unknown function FYB61_RS01015 ENOG4105SYT Methylenetetrahydrofolate reductase FYB61_RS01020 ENOG4105DUM transcriptional regulator, lysR family FYB61_RS01030 ENOG4105CSH Transporter FYB61_RS01040 ENOG4107SC1 transglycosylase FYB61_RS01055 ENOG4105C1J atp-dependent rna helicase FYB61_RS01065 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 FYB61_RS01070 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) FYB61_RS01085 ENOG41090R7 Ferric uptake FYB61_RS01105 ENOG4105E2K Glycosyl transferase (Group 1 FYB61_RS01120 ENOG4105CSR polyphosphate kinase 2 FYB61_RS01130 ENOG41080HT Transcriptional regulator, arsr family FYB61_RS01145 ENOG4105DZS Phenylacetate-CoA ligase FYB61_RS01150 ENOG4108IV0 ABC, transporter FYB61_RS01165 ENOG4105C32 Amino acid ABC transporter (Permease) FYB61_RS01170 ENOG4105C0Z ABC transporter FYB61_RS01190 ENOG4105CXD Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity) FYB61_RS01205 ENOG4105DFA alanine racemase domain protein FYB61_RS01210 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FYB61_RS01215 ENOG4107QXX ABC transporter FYB61_RS01225 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase FYB61_RS01230 ENOG4105C79 DNA protecting protein DprA FYB61_RS01235 ENOG4105F7P transcriptional regulator AsnC family FYB61_RS01245 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) FYB61_RS01260 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 FYB61_RS01270 ENOG4108URH decarboxylase FYB61_RS01280 ENOG4105CBM Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity) FYB61_RS01285 ENOG41084KP 4-oxalocrotonate tautomerase FYB61_RS01290 ENOG4105CJP fad dependent oxidoreductase FYB61_RS01325 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B FYB61_RS01335 ENOG4105ES5 Histidine kinase FYB61_RS01340 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family FYB61_RS01345 ENOG4105C1A potassium transporter peripheral membrane FYB61_RS01350 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) FYB61_RS01390 ENOG4108UAU isochorismatase FYB61_RS01415 ENOG4105CH5 extracellular solute-binding protein, family 7 FYB61_RS01445 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component FYB61_RS01455 ENOG4105CG6 trap dicarboxylate transporter dctm subunit FYB61_RS01465 ENOG4106T9E Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) FYB61_RS01490 ENOG4105IX2 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity) FYB61_RS01495 ENOG4105VW4 glutaredoxin 3 FYB61_RS01500 ENOG4105C72 UPF0176 protein FYB61_RS01510 ENOG41063SB peptidase FYB61_RS01515 ENOG4105CN1 protease FYB61_RS01520 ENOG4105D06 uba thif-type nad fad binding protein FYB61_RS01540 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) FYB61_RS01545 ENOG4105S7Q restriction endonuclease FYB61_RS01575 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control FYB61_RS01580 ENOG4105K46 50S ribosomal protein l27 FYB61_RS01585 ENOG4105KK9 This protein binds to 23S rRNA in the presence of protein L20 (By similarity) FYB61_RS01595 ENOG4105EAH synthase FYB61_RS01605 ENOG4105RQF LysR family Transcriptional regulator FYB61_RS01615 ENOG4107TYC hydantoinase B oxoprolinase FYB61_RS01620 ENOG4105DDR sarcosine oxidase (Beta subunit) FYB61_RS01625 ENOG4105JN3 extra-cytoplasmic solute receptor family protein FYB61_RS01635 ENOG41090Q8 at two internal lysine residues, thereby converting it to the active toxin. The acyl donor is ACP FYB61_RS01645 ENOG4107VZP Hemolysin-type calcium-binding repeat 2 copies family protein FYB61_RS01650 ENOG4108JJA ABC, transporter FYB61_RS01670 ENOG4107RP9 extracellular solute-binding protein, family 3 FYB61_RS01675 ENOG4105EAD ABC transporter FYB61_RS01680 ENOG4105DRP amino acid AbC transporter FYB61_RS01685 ENOG4105CDA abc transporter atp-binding protein FYB61_RS01705 ENOG4105CHR reductase FYB61_RS01715 ENOG4108WYP Transcriptional regulator FYB61_RS01730 ENOG4105DRR Transcriptional regulator, GntR family FYB61_RS01735 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein FYB61_RS01750 ENOG4105Y36 Binding-protein-dependent transport systems, inner membrane component FYB61_RS01780 ENOG4106P55 Transcriptional regulator FYB61_RS01785 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F FYB61_RS01790 ENOG4105CI0 Citrate lyase FYB61_RS01795 ENOG4105FDP GntR family transcriptional regulator FYB61_RS01815 ENOG4105JN3 extra-cytoplasmic solute receptor family protein FYB61_RS01840 ENOG4107F9Y LysR family transcriptional regulator FYB61_RS01850 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase FYB61_RS01860 ENOG4105C32 Amino acid ABC transporter (Permease) FYB61_RS01870 ENOG4105C0Z ABC transporter FYB61_RS01875 ENOG4108IV0 ABC, transporter FYB61_RS01880 ENOG4105H9W Short-chain dehydrogenase reductase Sdr FYB61_RS01890 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr FYB61_RS01895 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FYB61_RS01920 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FYB61_RS01960 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) FYB61_RS01970 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase FYB61_RS01980 ENOG4107BVJ 4,5-dihydroxyphthalate decarboxylase FYB61_RS02030 ENOG4108IV0 ABC, transporter FYB61_RS02035 ENOG4105C0Z ABC transporter FYB61_RS02040 ENOG4105C32 Amino acid ABC transporter (Permease) FYB61_RS02045 ENOG4108HWV )-transporter FYB61_RS02060 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) FYB61_RS02085 ENOG4105F2Z 3-oxoadipate enol-lactonase FYB61_RS02100 ENOG4107QNJ CoA-transferase subunit B FYB61_RS02110 ENOG4107HP6 Transcriptional regulator FYB61_RS02115 ENOG4105CHR reductase FYB61_RS02120 ENOG4105CRW Short chain fatty acid transporter FYB61_RS02125 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase FYB61_RS02160 ENOG4105JPG D-isomer specific 2-hydroxyacid dehydrogenase FYB61_RS02165 ENOG4105DEF Extracellular solute-binding protein, family 5 FYB61_RS02170 ENOG4105F2M alpha beta hydrolase fold-3 domain protein FYB61_RS02180 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) FYB61_RS02210 ENOG4105ENJ RND efflux system, outer membrane lipoprotein FYB61_RS02225 ENOG4105CBN LysR family transcriptional regulator FYB61_RS02230 ENOG4105IPI Membrane FYB61_RS02240 ENOG4107SVH Potassium channel protein FYB61_RS02245 ENOG4107YYT May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation (By similarity) FYB61_RS02255 ENOG4105EPW hflc protein FYB61_RS02260 ENOG4105KWI UPF0339 protein FYB61_RS02275 ENOG4105EJC lysr family transcriptional regulator FYB61_RS02310 ENOG4105CEY Amp-dependent synthetase and ligase FYB61_RS02315 ENOG4107258 Transcriptional regulator FYB61_RS02320 ENOG4108VUG Enoyl-CoA hydratase FYB61_RS02335 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family FYB61_RS02340 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F FYB61_RS02345 ENOG4105DND Transcriptional regulator FYB61_RS02355 ENOG4105IYB L-carnitine dehydratase bile acid-inducible protein F FYB61_RS02370 ENOG4108UQ8 endoribonuclease L-psp FYB61_RS02380 ENOG4105CRW Short chain fatty acid transporter FYB61_RS02410 ENOG4105VEQ Cold shock protein FYB61_RS02415 ENOG4105DND Transcriptional regulator FYB61_RS02435 ENOG4105CI2 imidazolone-5-propionate hydrolase FYB61_RS02440 ENOG4105CKI cobalamin synthesis protein FYB61_RS02525 ENOG4108TGY Glutathione S-transferase FYB61_RS02540 ENOG4105CRE cytochrome C FYB61_RS02545 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY FYB61_RS02550 ENOG4109066 lysm domain bon superfamily protein FYB61_RS02555 ENOG4105CA8 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity) FYB61_RS02575 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F FYB61_RS02580 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase FYB61_RS02615 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit FYB61_RS02670 ENOG4106KR7 LysR family Transcriptional regulator FYB61_RS02685 ENOG4105E39 Enoyl-CoA hydratase FYB61_RS02700 ENOG4105JN3 extra-cytoplasmic solute receptor family protein FYB61_RS02715 ENOG4105C7K acetolactate synthase FYB61_RS02725 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase FYB61_RS02735 ENOG4105J4Q Transcriptional regulator FYB61_RS02755 ENOG4105CEY Amp-dependent synthetase and ligase FYB61_RS02760 ENOG4105ETE Transcriptional regulator (LacI family FYB61_RS02785 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase FYB61_RS02790 ENOG4105E39 Enoyl-CoA hydratase FYB61_RS02795 ENOG4105C0A alcohol dehydrogenase FYB61_RS02805 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F FYB61_RS02815 ENOG4108KB2 LysR family Transcriptional regulator FYB61_RS02830 ENOG4105C1G acyl-Coa dehydrogenase FYB61_RS02845 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) FYB61_RS02850 ENOG4105DUM transcriptional regulator, lysR family FYB61_RS02855 ENOG4107EFR Flavocytochrome c FYB61_RS02870 ENOG4108IV0 ABC, transporter FYB61_RS02875 ENOG4105C0Z ABC transporter FYB61_RS02890 ENOG41083Z3 extracellular ligand-binding receptor FYB61_RS02900 ENOG4108W9H Tetr family transcriptional regulator FYB61_RS02920 ENOG4105CHR reductase FYB61_RS02925 ENOG4105C1G acyl-Coa dehydrogenase FYB61_RS02930 ENOG4105CHR reductase FYB61_RS02935 ENOG4105CEY Amp-dependent synthetase and ligase FYB61_RS02945 ENOG4108IPT Naphthoate synthase FYB61_RS02950 ENOG4105JN3 extra-cytoplasmic solute receptor family protein FYB61_RS02960 ENOG4105DAB fumarate reductase succinate dehydrogenase flavoprotein domain protein FYB61_RS02970 ENOG4105DJG MaoC domain protein dehydratase FYB61_RS02985 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F FYB61_RS03015 ENOG4105C32 Amino acid ABC transporter (Permease) FYB61_RS03030 ENOG4108IV0 ABC, transporter FYB61_RS03035 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FYB61_RS03050 ENOG4105CYC Transferase FYB61_RS03055 ENOG4105CEY Amp-dependent synthetase and ligase FYB61_RS03070 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) FYB61_RS03085 ENOG4105CHR reductase FYB61_RS03090 ENOG4105CHU acetyl-coa acetyltransferase FYB61_RS03095 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) FYB61_RS03105 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F FYB61_RS03110 ENOG4105DND Transcriptional regulator FYB61_RS03115 ENOG4105C1G acyl-Coa dehydrogenase FYB61_RS03125 ENOG4105C10 Electron transfer flavoprotein FYB61_RS03130 ENOG4108M9J MaoC like domain protein FYB61_RS03150 ENOG4105JN3 extra-cytoplasmic solute receptor family protein FYB61_RS03155 ENOG4108RZE Tetr family transcriptional regulator FYB61_RS03165 ENOG4105E39 Enoyl-CoA hydratase FYB61_RS03180 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase FYB61_RS03185 ENOG4105E39 Enoyl-CoA hydratase FYB61_RS03190 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F FYB61_RS03200 ENOG4105C0A alcohol dehydrogenase FYB61_RS03205 ENOG4108UKI Enoyl-CoA hydratase FYB61_RS03225 ENOG4105C26 Dehydrogenase FYB61_RS03230 ENOG4108UZX fmn reductase FYB61_RS03235 ENOG4108I05 Binding-protein-dependent transport systems, inner membrane component FYB61_RS03255 ENOG4107HP6 Transcriptional regulator FYB61_RS03260 ENOG4105IJJ transcriptional regulator, crp fnr family FYB61_RS03265 ENOG4105CHR reductase FYB61_RS03295 ENOG4105CEY Amp-dependent synthetase and ligase FYB61_RS03315 ENOG4105CGU Enoyl-CoA hydratase FYB61_RS03325 ENOG4105C1G acyl-Coa dehydrogenase FYB61_RS03330 ENOG4105E39 Enoyl-CoA hydratase FYB61_RS03335 ENOG4105CHU acetyl-coa acetyltransferase FYB61_RS03355 ENOG4105ETT transcriptional Regulator, LysR family FYB61_RS03360 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) FYB61_RS03375 ENOG4108K3A Glutathione S-transferase FYB61_RS03390 ENOG4105C6F GntR Family Transcriptional Regulator FYB61_RS03395 ENOG4105C26 Dehydrogenase FYB61_RS03400 ENOG4105C28 cystathionine FYB61_RS03420 ENOG4107QRP cobalamin biosynthesis protein CobW FYB61_RS03440 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) FYB61_RS03450 ENOG4105EAB amino acid AbC transporter FYB61_RS03455 ENOG4105E5Q amino acid AbC transporter FYB61_RS03470 ENOG41069M3 Transcriptional regulator FYB61_RS03480 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) FYB61_RS03495 ENOG4105CG6 trap dicarboxylate transporter dctm subunit FYB61_RS03540 ENOG4105CH5 extracellular solute-binding protein, family 7 FYB61_RS03555 ENOG4105DKK Benzoate FYB61_RS03570 ENOG4105DUM transcriptional regulator, lysR family FYB61_RS03580 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase FYB61_RS03605 ENOG41064HX Suppressor of fused protein (SUFU) FYB61_RS03665 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit FYB61_RS03690 ENOG4106VK6 Flagellar motor protein FYB61_RS03720 ENOG4105F4K antigen 43 FYB61_RS03735 ENOG4105E0C molybdate abc transporter FYB61_RS03740 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein FYB61_RS03780 ENOG4105C8Y Acetylornithine aminotransferase FYB61_RS03865 ENOG4105CXN decarboxylase FYB61_RS03870 ENOG4105CBX hi0933 family FYB61_RS03890 ENOG4105KE9 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity) FYB61_RS03915 ENOG4105E39 Enoyl-CoA hydratase FYB61_RS03935 ENOG4108JQ6 ABC transporter FYB61_RS03955 ENOG4105C26 Dehydrogenase FYB61_RS03960 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) FYB61_RS03990 ENOG4107UKG Glycosyl transferase, family 4 FYB61_RS03995 ENOG4107QQG Dehydrogenase FYB61_RS04010 ENOG4105CG5 Glycosyl transferase (Group 1 FYB61_RS04020 ENOG4107XU6 Glycosyl transferase (Group 1 FYB61_RS04025 ENOG4108KMV Glycosyl transferase (Group 1 FYB61_RS04030 ENOG4105CGN Glycosyl transferase (Group 1 FYB61_RS04035 ENOG4107QP8 phosphohexose isomerase FYB61_RS04040 ENOG4107QKV phosphomannomutase FYB61_RS04050 ENOG4105CQB FAD linked oxidase domain protein FYB61_RS04055 ENOG4105XJC Two component transcriptional regulator (Winged helix family FYB61_RS04060 ENOG4105DHQ Histidine kinase FYB61_RS04065 ENOG4105E0M Sulfatase FYB61_RS04095 ENOG4105E2Q 3-(3-hydroxy-phenyl)propionate hydroxylase FYB61_RS04110 ENOG4105DJQ tetratricopeptide tpr_2 repeat protein FYB61_RS04150 ENOG4105C3G gtp-binding protein FYB61_RS04165 ENOG4108KXV response regulator FYB61_RS04175 ENOG4108W9H Tetr family transcriptional regulator FYB61_RS04185 ENOG4105DXI Major Facilitator superfamily FYB61_RS04210 ENOG4105C6K Malic enzyme FYB61_RS04230 ENOG4108JQ6 ABC transporter FYB61_RS04245 ENOG4105F04 LysR family Transcriptional regulator FYB61_RS04260 ENOG41082BM Transcriptional regulator, arsr family FYB61_RS04275 ENOG4105DKK Benzoate FYB61_RS04280 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding FYB61_RS04285 ENOG4108ZEF Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity) FYB61_RS04290 ENOG4106H78 methyltransferase FYB61_RS04335 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) FYB61_RS04340 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) FYB61_RS04345 ENOG4107YIM Involved in the transcription termination process (By similarity) FYB61_RS04350 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) FYB61_RS04355 ENOG4108ZAI phosphatidylglycerophosphatase a FYB61_RS04360 ENOG4108I62 cina-like protein FYB61_RS04365 ENOG4105SKN orotidine 5''-phosphate decarboxylase FYB61_RS04370 ENOG4105CEP NADH dehydrogenase FYB61_RS04375 ENOG41080IJ Diacylglycerol kinase FYB61_RS04380 ENOG4107S2Z UPF0761 membrane protein FYB61_RS04395 ENOG4105K5Y Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity) FYB61_RS04415 ENOG4105DAB fumarate reductase succinate dehydrogenase flavoprotein domain protein FYB61_RS04425 ENOG4105DUM transcriptional regulator, lysR family FYB61_RS04430 ENOG4105DAB fumarate reductase succinate dehydrogenase flavoprotein domain protein FYB61_RS04440 ENOG4107HP6 Transcriptional regulator FYB61_RS04455 ENOG4105CHJ isochorismatase hydrolase FYB61_RS04470 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) FYB61_RS04485 ENOG4105C1G acyl-Coa dehydrogenase FYB61_RS04490 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F FYB61_RS04500 ENOG4107RSM transcriptional regulator FYB61_RS04530 ENOG4105CN8 Transcriptional regulator FYB61_RS04535 ENOG4108K0B C-di-gmp phosphodiesterase FYB61_RS04560 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FYB61_RS04590 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase FYB61_RS04595 ENOG4105CEY Amp-dependent synthetase and ligase FYB61_RS04600 ENOG4105JN3 extra-cytoplasmic solute receptor family protein FYB61_RS04605 ENOG4105BZU Histidine kinase FYB61_RS04620 ENOG4105CEY Amp-dependent synthetase and ligase FYB61_RS04625 ENOG4105CSU acyl-Coa dehydrogenase FYB61_RS04665 ENOG4108Z9Z response to DNA damage stimulus FYB61_RS04680 ENOG4105GRZ Ycii-related protein FYB61_RS04710 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) FYB61_RS04715 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F FYB61_RS04720 ENOG4105E39 Enoyl-CoA hydratase FYB61_RS04745 ENOG41061TZ Short-chain dehydrogenase reductase Sdr FYB61_RS04750 ENOG41069M3 Transcriptional regulator FYB61_RS04755 ENOG4105CP9 extracellular ligand-binding receptor FYB61_RS04770 ENOG4107Z5Z endoribonuclease L-PSP FYB61_RS04775 ENOG4105C32 Amino acid ABC transporter (Permease) FYB61_RS04785 ENOG4105C0Z ABC transporter FYB61_RS04790 ENOG4108IV0 ABC, transporter FYB61_RS04795 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FYB61_RS04800 ENOG4105HEI LysR family (Transcriptional regulator FYB61_RS04810 ENOG4107Y2X deaminase FYB61_RS04815 ENOG4105DJ2 Major Facilitator Superfamily FYB61_RS04820 ENOG4108R6K riboflavin synthase, subunit alpha FYB61_RS04830 ENOG4108XM1 transcriptional regulator AsnC family FYB61_RS04840 ENOG4105CEY Amp-dependent synthetase and ligase FYB61_RS04850 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component FYB61_RS04890 ENOG4105EST Metal Dependent Phosphohydrolase FYB61_RS04900 ENOG4105CHJ isochorismatase hydrolase FYB61_RS04930 ENOG4108JJA ABC, transporter FYB61_RS04940 ENOG4105DFG type I secretion outer membrane protein FYB61_RS04945 ENOG4105BZ8 glutamate synthase FYB61_RS04955 ENOG4107R5R arsenical pump membrane protein FYB61_RS04965 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F FYB61_RS04980 ENOG4105C1G acyl-Coa dehydrogenase FYB61_RS04985 ENOG4105F6U Short-chain dehydrogenase reductase Sdr FYB61_RS04990 ENOG4105KPY Small multidrug resistance protein FYB61_RS04995 ENOG4108IND Tetr family transcriptional regulator FYB61_RS05015 ENOG4105C8Q Methyl-accepting chemotaxis FYB61_RS05030 ENOG4105MDH Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) FYB61_RS05055 ENOG4105C26 Dehydrogenase FYB61_RS05065 ENOG41060WC Enoyl-CoA hydratase FYB61_RS05075 ENOG410620I Diguanylate cyclase FYB61_RS05095 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) FYB61_RS05100 ENOG4105CG6 trap dicarboxylate transporter dctm subunit FYB61_RS05125 ENOG4105NSG hemerythrin hhe cation binding domain protein FYB61_RS05140 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) FYB61_RS05160 ENOG4105C4M (Ubiquinol oxidase) subunit I FYB61_RS05165 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii FYB61_RS05175 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FYB61_RS05185 ENOG4105DB1 molybdopterin oxidoreductase FYB61_RS05190 ENOG4106WHD Tetrathionate reductase FYB61_RS05195 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein FYB61_RS05205 ENOG4105CPT Alpha beta hydrolase FYB61_RS05210 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) FYB61_RS05245 ENOG4105JSC dimethylmenaquinone methyltransferase FYB61_RS05260 ENOG4105EA8 2-Nitropropane dioxygenase FYB61_RS05265 ENOG4105EGI Transcriptional regulator FYB61_RS05275 ENOG4106AXJ AraC family transcriptional regulator FYB61_RS05290 ENOG4105CSR polyphosphate kinase 2 FYB61_RS05305 ENOG4105C7B Threonine dehydratase FYB61_RS05335 ENOG4105C5Q Transcriptional regulator FYB61_RS05350 ENOG4105F52 Transcriptional regulator FYB61_RS05375 ENOG4108UYB regulatoR FYB61_RS05380 ENOG4105E2S oxidase) subunit II FYB61_RS05385 ENOG4105BZ9 Cytochrome C oxidase, subunit I FYB61_RS05390 ENOG4105CCU oxidase (Subunit III) FYB61_RS05395 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) FYB61_RS05400 ENOG4105YVS arsR family transcriptional regulator FYB61_RS05435 ENOG4105E0K tonB-dependent siderophore receptor FYB61_RS05465 ENOG4108VPT UPF0234 protein FYB61_RS05490 ENOG4105CHR reductase FYB61_RS05500 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) FYB61_RS05505 ENOG4105CCU oxidase (Subunit III) FYB61_RS05510 ENOG4105BZ9 Cytochrome C oxidase, subunit I FYB61_RS05515 ENOG4105E2S oxidase) subunit II FYB61_RS05520 ENOG4105CSH Transporter FYB61_RS05535 ENOG4107AQZ Membrane FYB61_RS05540 ENOG41068KF Universal stress protein FYB61_RS05555 ENOG4107S47 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity) FYB61_RS05570 ENOG4108IEG Formate dehydrogenase Alpha subunit FYB61_RS05590 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) FYB61_RS05595 ENOG4105CVM Molybdenum cofactor synthesis domain protein FYB61_RS05600 ENOG4108RIR Molybdenum cofactor biosynthesis protein FYB61_RS05605 ENOG4108ZAF Molybdopterin FYB61_RS05610 ENOG4105M00 molybdopterin converting factor, subunit 1 FYB61_RS05625 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) FYB61_RS05645 ENOG4108TZV Membrane FYB61_RS05690 ENOG4107QM5 aconitate hydratase FYB61_RS05695 ENOG4105CD3 dihydroorotase FYB61_RS05700 ENOG4108UAU isochorismatase FYB61_RS05705 ENOG4105CKI cobalamin synthesis protein FYB61_RS05735 ENOG4105DRR Transcriptional regulator, GntR family FYB61_RS05755 ENOG4107SET aldo keto reductase FYB61_RS05765 ENOG4108JU5 Magnesium and cobalt efflux protein FYB61_RS05775 ENOG4105C9A Phoh family FYB61_RS05790 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) FYB61_RS05795 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) FYB61_RS05800 ENOG4105VIE preprotein translocase, subunit YajC FYB61_RS05805 ENOG4105C6U Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity) FYB61_RS05815 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase FYB61_RS05860 ENOG4106S48 Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division FYB61_RS05865 ENOG4105CHM Aminotransferase FYB61_RS05875 ENOG4105C6K Malic enzyme FYB61_RS05890 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) FYB61_RS05895 ENOG4105CV1 Transketolase (EC 2.2.1.1) FYB61_RS05900 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase FYB61_RS05910 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH FYB61_RS05915 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) FYB61_RS05930 ENOG4108SHQ Glutathione S-transferase FYB61_RS05960 ENOG4108UMN azlc family FYB61_RS05970 ENOG4105CJ3 phosphate transporter FYB61_RS05975 ENOG4108RIR Molybdenum cofactor biosynthesis protein FYB61_RS05985 ENOG4105DR5 peptidase FYB61_RS05995 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) FYB61_RS06015 ENOG4105IW1 AmiS UreI transporter FYB61_RS06045 ENOG4105C8V SAICAR synthetase FYB61_RS06065 ENOG4105RXK Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity) FYB61_RS06070 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) FYB61_RS06075 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit FYB61_RS06080 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) FYB61_RS06090 ENOG4108FUF Transcriptional regulator, IclR family FYB61_RS06095 ENOG4105CYW agmatinase FYB61_RS06105 ENOG4105E5Q amino acid AbC transporter FYB61_RS06110 ENOG4105CDA abc transporter atp-binding protein FYB61_RS06125 ENOG4105C1G acyl-Coa dehydrogenase FYB61_RS06130 ENOG4105C7K acetolactate synthase FYB61_RS06135 ENOG4105ETT transcriptional Regulator, LysR family FYB61_RS06140 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FYB61_RS06145 ENOG4108Z66 YbaK ebsC protein FYB61_RS06150 ENOG4108UHX Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity) FYB61_RS06160 ENOG41061WM D-Alanyl-D-Alanine FYB61_RS06185 ENOG4107R2I The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation FYB61_RS06195 ENOG4107QMP dna polymerase iii subunits gamma and tau FYB61_RS06210 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F FYB61_RS06215 ENOG4105D2X ABC transporter substrate-binding protein FYB61_RS06225 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component FYB61_RS06235 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain FYB61_RS06240 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain FYB61_RS06250 ENOG4108YZN class I peptide chain release factor FYB61_RS06270 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) FYB61_RS06300 ENOG4107EFR Flavocytochrome c FYB61_RS06310 ENOG4108QIU Dehydrogenase FYB61_RS06325 ENOG4105E98 transcriptional regulator DeoR family FYB61_RS06335 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FYB61_RS06370 ENOG4105EW9 transcriptional regulator AsnC family FYB61_RS06380 ENOG4107RH8 nuclease SbcCD subunit D FYB61_RS06395 ENOG4105D65 subunit l FYB61_RS06400 ENOG4108ZE9 Monovalent cation H antiporter subunit C FYB61_RS06405 ENOG4107R4Z monovalent cation h antiporter subunit d FYB61_RS06410 ENOG4105SC1 monovalent cation H antiporter subunit E FYB61_RS06415 ENOG4105W4C monovalent cation H antiporter subunit F FYB61_RS06430 ENOG4106TCE FYB61_RS06435 ENOG4108Z6B deaminase FYB61_RS06440 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A FYB61_RS06445 ENOG4105E39 Enoyl-CoA hydratase FYB61_RS06450 ENOG4105CG6 trap dicarboxylate transporter dctm subunit FYB61_RS06460 ENOG4105CH5 extracellular solute-binding protein, family 7 FYB61_RS06465 ENOG4105C5H ABC transporter FYB61_RS06495 ENOG41080RH Thioredoxin FYB61_RS06500 ENOG4105DEN Luciferase family FYB61_RS06505 ENOG4105C7N Xanthine uracil vitamin C permease FYB61_RS06515 ENOG4105K7Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) FYB61_RS06530 ENOG4108K5P (LipO)protein FYB61_RS06565 ENOG4105EHV domain protein FYB61_RS06575 ENOG4105D6S protein involved in catabolism of external DNA FYB61_RS06580 ENOG4107T6V glycerophosphoryl diester phosphodiesterase FYB61_RS06585 ENOG4105EIN peptidylprolyl cis-trans isomerase FYB61_RS06590 ENOG4108UJV acyl-CoA thioesterase i FYB61_RS06595 ENOG4108I0Y (ABC) transporter FYB61_RS06605 ENOG4105EGI Transcriptional regulator FYB61_RS06635 ENOG4105CFM UPF0317 protein FYB61_RS06650 ENOG4108WQH regulatoR FYB61_RS06660 ENOG4108QZZ filamentous hemagglutinin FYB61_RS06670 ENOG4105GQR Chaperone FYB61_RS06680 ENOG41074HU Fimbrial adhesin FYB61_RS06685 ENOG4108YH7 hemolysin FYB61_RS06700 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit FYB61_RS06705 ENOG4105CG6 trap dicarboxylate transporter dctm subunit FYB61_RS06725 ENOG4107NQ8 LysR family Transcriptional regulator FYB61_RS06745 ENOG4107R0W ABC transporter FYB61_RS06750 ENOG4105E5Q amino acid AbC transporter FYB61_RS06755 ENOG4105CDA abc transporter atp-binding protein FYB61_RS06760 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) FYB61_RS06765 ENOG4105VFG Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity) FYB61_RS06770 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) FYB61_RS06780 ENOG41090Y2 cytochrome C FYB61_RS06785 ENOG41061TZ Short-chain dehydrogenase reductase Sdr FYB61_RS06790 ENOG4105K4H Nlp p60 protein FYB61_RS06795 ENOG4105FYV Amp nucleosidase FYB61_RS06825 ENOG4105DUM transcriptional regulator, lysR family FYB61_RS06835 ENOG4105BZU Histidine kinase FYB61_RS06845 ENOG4105CSA Coproporphyrinogen iii oxidase FYB61_RS06855 ENOG4105CUX Signal transduction histidine kinase FYB61_RS06860 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family FYB61_RS06865 ENOG4105EQ1 Transcriptional regulator FYB61_RS06875 ENOG4105EUB pirin domain protein FYB61_RS06880 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FYB61_RS06890 ENOG4107QKW extracellular solute-binding protein family 1 FYB61_RS06895 ENOG4105DP0 ferredoxin-NADP reductase FYB61_RS06900 ENOG4105HEI LysR family (Transcriptional regulator FYB61_RS06905 ENOG4105F27 Major Facilitator FYB61_RS06910 ENOG4105CV8 reductase FYB61_RS06915 ENOG4108P8G outer membrane autotransporter barrel FYB61_RS06920 ENOG4105KME endoribonuclease L-psp FYB61_RS06925 ENOG4105CB5 ATP-dependent DNA helicase recG FYB61_RS06930 ENOG4105C5Q Transcriptional regulator FYB61_RS06935 ENOG4105JQN Transcriptional regulator FYB61_RS06940 ENOG4105C26 Dehydrogenase FYB61_RS06960 ENOG4105K64 Glycosyl transferase, family 2 FYB61_RS06980 ENOG4107TAE Glycosyl transferase (Group 1 FYB61_RS06995 ENOG4107QQG Dehydrogenase FYB61_RS07010 ENOG41084CK capsule polysaccharide FYB61_RS07015 ENOG4108W6C Dehydrogenase FYB61_RS07040 ENOG4105CP9 extracellular ligand-binding receptor FYB61_RS07055 ENOG4105E4X binding-protein-dependent transport systems inner membrane Component FYB61_RS07060 ENOG4105BZ7 extracellular solute-binding protein family 1 FYB61_RS07065 ENOG4105II7 pyrroline-5-carboxylate reductase FYB61_RS07070 ENOG4105EX9 Membrane FYB61_RS07075 ENOG4105CP9 extracellular ligand-binding receptor FYB61_RS07080 ENOG4105C32 Amino acid ABC transporter (Permease) FYB61_RS07085 ENOG4105CF8 branched-chain amino acid ABC transporter, permease FYB61_RS07090 ENOG4105C0Z ABC transporter FYB61_RS07095 ENOG4108IV0 ABC, transporter FYB61_RS07105 ENOG4108K3A Glutathione S-transferase FYB61_RS07110 ENOG4105D8V Glucose sorbosone dehydrogenase FYB61_RS07150 ENOG4105D01 (LipO)protein FYB61_RS07160 ENOG4105DJ4 phosphatidylserine decarboxylase FYB61_RS07185 ENOG4105CYM Glutathione S-transferase FYB61_RS07190 ENOG4108V06 Glutathione peroxidase FYB61_RS07205 ENOG4105WAP TPR repeat-containing protein FYB61_RS07230 ENOG4108VGI doxx family FYB61_RS07235 ENOG4105D4Y metalloprotease FYB61_RS07245 ENOG4105CPC Aldo Keto reductase FYB61_RS07250 ENOG41068KF Universal stress protein FYB61_RS07265 ENOG4105CSW GntR family transcriptional regulator FYB61_RS07270 ENOG4105DFA alanine racemase domain protein FYB61_RS07290 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) FYB61_RS07340 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FYB61_RS07350 ENOG4105C5Q Transcriptional regulator FYB61_RS07380 ENOG4108JQ6 ABC transporter FYB61_RS07435 ENOG41082K8 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity) FYB61_RS07460 ENOG4105C9B Cysteine desulfurase FYB61_RS07470 ENOG4105DHQ Histidine kinase FYB61_RS07475 ENOG4105XJC Two component transcriptional regulator (Winged helix family FYB61_RS07490 ENOG4108UGX Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity) FYB61_RS07515 ENOG4105N21 Membrane FYB61_RS07520 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) FYB61_RS07525 ENOG4105DKZ GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity) FYB61_RS07535 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) FYB61_RS07540 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) FYB61_RS07545 ENOG4107QJR hflk protein FYB61_RS07550 ENOG4105EPW hflc protein FYB61_RS07565 ENOG4108UGV hypoxanthine phosphoribosyltransferase FYB61_RS07570 ENOG4105VCC 30S ribosomal protein S21 FYB61_RS07625 ENOG4108IV0 ABC, transporter FYB61_RS07630 ENOG4105C0Z ABC transporter FYB61_RS07635 ENOG4105CF8 branched-chain amino acid ABC transporter, permease FYB61_RS07640 ENOG4105C32 Amino acid ABC transporter (Permease) FYB61_RS07645 ENOG4105CP9 extracellular ligand-binding receptor FYB61_RS07650 ENOG4105FUY alpha subunit FYB61_RS07660 ENOG4105E39 Enoyl-CoA hydratase FYB61_RS07665 ENOG4105CHR reductase FYB61_RS07670 ENOG4107Z7P Ferredoxin FYB61_RS07675 ENOG410846T CoA-transferase family III FYB61_RS07685 ENOG4105DZS Phenylacetate-CoA ligase FYB61_RS07690 ENOG4105CHU acetyl-coa acetyltransferase FYB61_RS07700 ENOG4108NVI FYB61_RS07710 ENOG4105JN3 extra-cytoplasmic solute receptor family protein FYB61_RS07725 ENOG4105C26 Dehydrogenase FYB61_RS07730 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F FYB61_RS07745 ENOG4108M8H domain protein FYB61_RS07755 ENOG4108JU7 Transcriptional regulator FYB61_RS07785 ENOG4108IQI permease FYB61_RS07805 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F FYB61_RS07810 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit FYB61_RS07815 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase FYB61_RS07830 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component FYB61_RS07835 ENOG4105F38 ABC transporter, permease FYB61_RS07850 ENOG4105J4Q Transcriptional regulator FYB61_RS07855 ENOG4105H9W Short-chain dehydrogenase reductase Sdr FYB61_RS07865 ENOG4105FDP GntR family transcriptional regulator FYB61_RS07870 ENOG4105CG6 trap dicarboxylate transporter dctm subunit FYB61_RS07895 ENOG4105DDW LysR family Transcriptional regulator FYB61_RS07915 ENOG4105CNN ABC, transporter FYB61_RS07925 ENOG4105ERH Fumarylacetoacetate hydrolase FYB61_RS07935 ENOG4105CI2 imidazolone-5-propionate hydrolase FYB61_RS07940 ENOG4106HB6 Alpha beta hydrolase FYB61_RS07965 ENOG4108ZCF integral membrane protein FYB61_RS07985 ENOG4105E6M Sulphatase-modifying factor protein FYB61_RS08025 ENOG4105ENH Sulfatase FYB61_RS08045 ENOG4105WH1 Two component transcriptional regulator luxr family FYB61_RS08055 ENOG4105W08 virulence gene repressor rsal FYB61_RS08060 ENOG4105W2W Cytotoxic translational repressor of toxin-antitoxin stability system FYB61_RS08065 ENOG4108K3A Glutathione S-transferase FYB61_RS08080 ENOG41061MV Arylsulfatase FYB61_RS08095 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F FYB61_RS08100 ENOG4105CHU acetyl-coa acetyltransferase FYB61_RS08120 ENOG4107RSM transcriptional regulator FYB61_RS08150 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase FYB61_RS08160 ENOG4105C0A alcohol dehydrogenase FYB61_RS08185 ENOG4105DUM transcriptional regulator, lysR family FYB61_RS08190 ENOG4105CAU Arsenical resistance protein, ArsH FYB61_RS08220 ENOG4105CHR reductase FYB61_RS08250 ENOG4107QX8 SPFH domain, Band 7 family protein FYB61_RS08255 ENOG4105CDA abc transporter atp-binding protein FYB61_RS08280 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) FYB61_RS08285 ENOG41060IM Heme exporter protein FYB61_RS08300 ENOG4105DA4 cytochrome c-type biogenesis protein FYB61_RS08305 ENOG4107QX9 Thiol disulfide interChange protein FYB61_RS08310 ENOG4105KWW Biogenesis protein FYB61_RS08315 ENOG4108M1T Cytochrome c-type biogenesis protein FYB61_RS08325 ENOG4105KME endoribonuclease L-psp FYB61_RS08335 ENOG4105CMJ mandelate racemase muconate lactonizing FYB61_RS08355 ENOG4105ETE Transcriptional regulator (LacI family FYB61_RS08370 ENOG4105HEI LysR family (Transcriptional regulator FYB61_RS08390 ENOG4105NTW Transcriptional regulator FYB61_RS08400 ENOG4105X23 Endonuclease Exonuclease phosphatase FYB61_RS08410 ENOG4107UXM Membrane FYB61_RS08425 ENOG4105CEV competence damage-inducible protein FYB61_RS08445 ENOG4105TNS Conserved Protein FYB61_RS08450 ENOG4105FDF Could be involved in DNA repair (By similarity) FYB61_RS08460 ENOG4105CYX Short-chain dehydrogenase reductase Sdr FYB61_RS08520 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family FYB61_RS08525 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family FYB61_RS08545 ENOG4105F0N pyrophosphate phospho-hydrolase FYB61_RS08570 ENOG4108ZCF integral membrane protein FYB61_RS08575 ENOG4108ZCF integral membrane protein FYB61_RS08580 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha FYB61_RS08585 ENOG4105CMV Succinyl-CoA synthetase subunit beta FYB61_RS08600 ENOG4105DZ2 Transcriptional regulator FYB61_RS08605 ENOG4108004 Modulates RecA activity (By similarity) FYB61_RS08610 ENOG4105C68 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity) FYB61_RS08620 ENOG4105DHQ Histidine kinase FYB61_RS08625 ENOG4105CSH Transporter FYB61_RS08630 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase FYB61_RS08635 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FYB61_RS08650 ENOG4105CHR reductase FYB61_RS08665 ENOG4105CHU acetyl-coa acetyltransferase FYB61_RS08670 ENOG4105ETT transcriptional Regulator, LysR family FYB61_RS08675 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F FYB61_RS08690 ENOG4105CXT aspartate transcarbamylase FYB61_RS08725 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FYB61_RS08740 ENOG4108RYR transcriptional regulator AsnC family FYB61_RS08750 ENOG4108J4B Beta-lactamase FYB61_RS08765 ENOG4106R49 Methyltransferase FYB61_RS08805 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) FYB61_RS08810 ENOG4105VJV 50s ribosomal protein L35 FYB61_RS08815 ENOG4105C0P Mg chelatase subunit ChlI FYB61_RS08820 ENOG4105W0Z cytoplasmic protein FYB61_RS08825 ENOG4108YZA Nitrogen regulatory protein pii FYB61_RS08830 ENOG4105BZU Histidine kinase FYB61_RS08845 ENOG41060BG Tetr family transcriptional regulator FYB61_RS08855 ENOG4108IV0 ABC, transporter FYB61_RS08860 ENOG4105C0Z ABC transporter FYB61_RS08865 ENOG4105CF8 branched-chain amino acid ABC transporter, permease FYB61_RS08870 ENOG4105C32 Amino acid ABC transporter (Permease) FYB61_RS08880 ENOG4105C26 Dehydrogenase FYB61_RS08890 ENOG4105DY2 Paraquat-inducible protein b FYB61_RS08895 ENOG4105F1S paraquat-inducible protein a FYB61_RS08900 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit FYB61_RS08905 ENOG4108JQB penicillin-binding protein 1C FYB61_RS08920 ENOG4105VEQ Cold shock protein FYB61_RS08940 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FYB61_RS08955 ENOG4109015 Biopolymer transport protein exbD tolR FYB61_RS08965 ENOG4105W49 UPF0434 protein FYB61_RS08985 ENOG4105CJR Integral membrane protein (MviN FYB61_RS08995 ENOG41082GY Binds directly to 16S ribosomal RNA (By similarity) FYB61_RS09015 ENOG4105DG4 malate L-lactate dehydrogenase FYB61_RS09020 ENOG4107YCY Transcriptional regulator FYB61_RS09040 ENOG4105C5I Dehydrogenase FYB61_RS09045 ENOG4105CHR reductase FYB61_RS09050 ENOG4105CBN LysR family transcriptional regulator FYB61_RS09065 ENOG4105DBV ornithine carbamoyltransferase FYB61_RS09075 ENOG4105DFH Transport of potassium into the cell (By similarity) FYB61_RS09080 ENOG4105DHQ Histidine kinase FYB61_RS09085 ENOG4105XJC Two component transcriptional regulator (Winged helix family FYB61_RS09110 ENOG4105K70 DNA-binding protein FYB61_RS09115 ENOG4107E2E PKHD-type hydroxylase FYB61_RS09120 ENOG4105C28 cystathionine FYB61_RS09125 ENOG4105C2N RNA methyltransferase TrmH family group 3 FYB61_RS09130 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) FYB61_RS09150 ENOG4108HPG -acetyltransferase FYB61_RS09155 ENOG4105RK9 auxin efflux carrier FYB61_RS09165 ENOG4105CBC glutamate synthase FYB61_RS09170 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) FYB61_RS09180 ENOG41067HS methyltransferase FYB61_RS09215 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase FYB61_RS09220 ENOG4105BZU Histidine kinase FYB61_RS09255 ENOG4105T86 cytochrome C FYB61_RS09260 ENOG4107QTF adenylosuccinate lyase FYB61_RS09265 ENOG4108U78 Glutathione S-transferase FYB61_RS09280 ENOG4105ETT transcriptional Regulator, LysR family FYB61_RS09295 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) FYB61_RS09300 ENOG4105W8H transhydrogenase (subunit alpha FYB61_RS09305 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) FYB61_RS09315 ENOG4107RNH Outer membrane receptor FepA FYB61_RS09320 ENOG4105NIV Esterase FYB61_RS09325 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) FYB61_RS09335 ENOG4105CQB FAD linked oxidase domain protein FYB61_RS09340 ENOG4105CQB FAD linked oxidase domain protein FYB61_RS09345 ENOG4108QZZ filamentous hemagglutinin FYB61_RS09345 ENOG4108QZZ filamentous hemagglutinin FYB61_RS09350 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) FYB61_RS09355 ENOG4105D1U peptidase U62 modulator of DNA gyrase FYB61_RS09365 ENOG4105VFQ Histone family protein nucleoid-structuring protein H-NS FYB61_RS09375 ENOG4105CD8 aminopeptidase N FYB61_RS09380 ENOG4105CZI D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 FYB61_RS09395 ENOG4105D6E homoserine dehydrogenase FYB61_RS09400 ENOG4105CHM Aminotransferase FYB61_RS09405 ENOG4108UIV Protein of unknown function (DUF498/DUF598) FYB61_RS09410 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen FYB61_RS09415 ENOG4108IAB Phoh family FYB61_RS09420 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) FYB61_RS09425 ENOG4105DHU Bile acid FYB61_RS09430 ENOG4105CDU Replicative dna helicase FYB61_RS09450 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) FYB61_RS09460 ENOG4108ZDX Binds together with S18 to 16S ribosomal RNA (By similarity) FYB61_RS09465 ENOG4105DZA Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity) FYB61_RS09475 ENOG4105CTB Polyprenyl synthetase FYB61_RS09480 ENOG41082UU Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) FYB61_RS09530 ENOG4108KAZ Involved in phosphonate degradation (By similarity) FYB61_RS09540 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FYB61_RS09545 ENOG4105DUM transcriptional regulator, lysR family FYB61_RS09555 ENOG4105KHC sulfurtransferase FYB61_RS09565 ENOG4105D0M Protease HtpX homolog FYB61_RS09570 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein FYB61_RS09575 ENOG4106UX7 integral membrane protein FYB61_RS09585 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes FYB61_RS09605 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) FYB61_RS09615 ENOG4105DEF Extracellular solute-binding protein, family 5 FYB61_RS09625 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FYB61_RS09635 ENOG4108JPW Aminotransferase FYB61_RS09640 ENOG4105K8K Cupin 2, conserved barrel FYB61_RS09650 ENOG4105CE7 Amidase, hydantoinase carbamoylase family FYB61_RS09660 ENOG4105C26 Dehydrogenase FYB61_RS09670 ENOG4105C8Y Acetylornithine aminotransferase FYB61_RS09675 ENOG4105D7A ATP-binding protein FYB61_RS09685 ENOG4105C12 Phosphoribosylglycinamide synthetase FYB61_RS09700 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) FYB61_RS09715 ENOG4108P8G outer membrane autotransporter barrel FYB61_RS09750 ENOG4108MGI Transcriptional regulator FYB61_RS09755 ENOG4105C09 Bile acid FYB61_RS09760 ENOG4105CYC Transferase FYB61_RS09765 ENOG4105CMU LysR family (Transcriptional regulator FYB61_RS09770 ENOG4105EGS Mechanosensitive ion channel FYB61_RS09785 ENOG4105P69 integral membrane protein FYB61_RS09790 ENOG4108594 Permease of the drug metabolite transporter FYB61_RS09815 ENOG4107QIJ Aconitate hydratase 2 FYB61_RS09825 ENOG41090EK ompa motb domain protein FYB61_RS09845 ENOG4107QM5 aconitate hydratase FYB61_RS09850 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b FYB61_RS09865 ENOG4105DRH Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) FYB61_RS09870 ENOG4105XUA cytochrome c FYB61_RS09880 ENOG4105EMN RNA polymerase sigma factor FYB61_RS09965 ENOG4105BZU Histidine kinase FYB61_RS09985 ENOG4108JQ5 ABC transporter FYB61_RS09990 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FYB61_RS10000 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein FYB61_RS10010 ENOG4105D7N magnesium and cobalt transport protein CorA FYB61_RS10030 ENOG4108JPW Aminotransferase FYB61_RS10035 ENOG4105C26 Dehydrogenase FYB61_RS10040 ENOG4105ECY inositol monophosphatase FYB61_RS10065 ENOG4105D7W serine acetyltransferase FYB61_RS10070 ENOG4107QP8 phosphohexose isomerase FYB61_RS10075 ENOG4107QKV phosphomannomutase FYB61_RS10085 ENOG4105WH1 Two component transcriptional regulator luxr family FYB61_RS10095 ENOG4107QPN acyl-Coa dehydrogenase FYB61_RS10100 ENOG4105CHU acetyl-coa acetyltransferase FYB61_RS10120 ENOG4105CHU acetyl-coa acetyltransferase FYB61_RS10130 ENOG4105CEY Amp-dependent synthetase and ligase FYB61_RS10155 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) FYB61_RS10160 ENOG4105CE2 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding FYB61_RS10165 ENOG4108UAU isochorismatase FYB61_RS10190 ENOG4108XHQ (2Fe-2S)-binding domain protein FYB61_RS10200 ENOG4108IV0 ABC, transporter FYB61_RS10205 ENOG4105C0Z ABC transporter FYB61_RS10220 ENOG4108VHT MarR family transcriptional regulator FYB61_RS10240 ENOG4107BJW polysaccharide deacetylase FYB61_RS10245 ENOG4105CND Glycosyl transferase, family 2 FYB61_RS10255 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FYB61_RS10280 ENOG4107YYT May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation (By similarity) FYB61_RS10290 ENOG4105K4P CoA-binding domain protein FYB61_RS10295 ENOG4107HP6 Transcriptional regulator FYB61_RS10300 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FYB61_RS10310 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FYB61_RS10335 ENOG4105RQF LysR family Transcriptional regulator FYB61_RS10345 ENOG41061TZ Short-chain dehydrogenase reductase Sdr FYB61_RS10355 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) FYB61_RS10360 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit FYB61_RS10365 ENOG4105CG6 trap dicarboxylate transporter dctm subunit FYB61_RS10370 ENOG4105XDZ Tripartite ATP-independent periplasmic transporter FYB61_RS10395 ENOG4105CFH Aspartokinase FYB61_RS10405 ENOG4107QM9 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity) FYB61_RS10420 ENOG4108PPB Seems to be required for the assembly of the photosystem I complex (By similarity) FYB61_RS10440 ENOG4105EE5 Membrane protein terC FYB61_RS10445 ENOG4105ECY inositol monophosphatase FYB61_RS10465 ENOG4105D64 Mechanosensitive ion channel FYB61_RS10500 ENOG4105WKW Pfam:DUF1458 FYB61_RS10510 ENOG4105EZE Cupin 4 family protein FYB61_RS10525 ENOG4105GJM (LipO)protein FYB61_RS10530 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) FYB61_RS10535 ENOG4108Z4T Peptidase M50 FYB61_RS10540 ENOG4107RTD sua5 ycio yrdc ywlc family protein FYB61_RS10545 ENOG4105CGZ zinc metallopeptidase FYB61_RS10585 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) FYB61_RS10590 ENOG41083UI stage II sporulation protein FYB61_RS10595 ENOG4105JGF anti-sigma regulatory factor serine threonine protein kinase FYB61_RS10600 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) FYB61_RS10785 ENOG4105EXG Transcriptional regulator FYB61_RS10830 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) FYB61_RS10835 ENOG4105CHR reductase FYB61_RS10840 ENOG4108IV0 ABC, transporter FYB61_RS10845 ENOG4105C0Z ABC transporter FYB61_RS10855 ENOG4105C32 Amino acid ABC transporter (Permease) FYB61_RS10880 ENOG4105CIF Ornithine Cyclodeaminase FYB61_RS10885 ENOG4105ERH Fumarylacetoacetate hydrolase FYB61_RS10900 ENOG4105EJC lysr family transcriptional regulator FYB61_RS10925 ENOG4105CG6 trap dicarboxylate transporter dctm subunit FYB61_RS10935 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit FYB61_RS10950 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit FYB61_RS10955 ENOG4107QX3 carboxylase FYB61_RS10960 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase FYB61_RS10965 ENOG4105FDP GntR family transcriptional regulator FYB61_RS10985 ENOG4107QSA Oxaloacetate decarboxylase FYB61_RS11000 ENOG4105DHT Metal Dependent Phosphohydrolase FYB61_RS11010 ENOG4105C26 Dehydrogenase FYB61_RS11020 ENOG4108T7K Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity) FYB61_RS11045 ENOG4105BZ1 (ABC) transporter FYB61_RS11055 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) FYB61_RS11075 ENOG4105C32 Amino acid ABC transporter (Permease) FYB61_RS11085 ENOG4105C0Z ABC transporter FYB61_RS11090 ENOG4108IV0 ABC, transporter FYB61_RS11130 ENOG4107NQ8 LysR family Transcriptional regulator FYB61_RS11155 ENOG4105JN3 extra-cytoplasmic solute receptor family protein FYB61_RS11195 ENOG4105CDA abc transporter atp-binding protein FYB61_RS11200 ENOG4105DRP amino acid AbC transporter FYB61_RS11205 ENOG4105EZ7 amino acid ABC transporter FYB61_RS11215 ENOG4105CH2 amidohydrolase FYB61_RS11220 ENOG4107RCH Diaminopropionate ammonia-lyase FYB61_RS11235 ENOG4105ERH Fumarylacetoacetate hydrolase FYB61_RS11245 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit FYB61_RS11250 ENOG4105XDZ Tripartite ATP-independent periplasmic transporter FYB61_RS11255 ENOG4105CG6 trap dicarboxylate transporter dctm subunit FYB61_RS11275 ENOG4105CJP fad dependent oxidoreductase FYB61_RS11280 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) FYB61_RS11285 ENOG4108IV0 ABC, transporter FYB61_RS11290 ENOG4108IUZ ABC transporter FYB61_RS11295 ENOG4105CF8 branched-chain amino acid ABC transporter, permease FYB61_RS11300 ENOG4105C32 Amino acid ABC transporter (Permease) FYB61_RS11320 ENOG4105F35 Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity) FYB61_RS11325 ENOG4105F95 Monooxygenase FYB61_RS11360 ENOG4105C32 Amino acid ABC transporter (Permease) FYB61_RS11370 ENOG4105C0Z ABC transporter FYB61_RS11375 ENOG4108IV0 ABC, transporter FYB61_RS11390 ENOG4105C32 Amino acid ABC transporter (Permease) FYB61_RS11395 ENOG4108IV0 ABC, transporter FYB61_RS11400 ENOG4105C0Z ABC transporter FYB61_RS11420 ENOG4105C0A alcohol dehydrogenase FYB61_RS11470 ENOG4105E2Z phosphate ABC transporter (Permease FYB61_RS11475 ENOG4105C8U phosphate abc transporter FYB61_RS11480 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) FYB61_RS11490 ENOG4105C9X ppx gppa phosphatase FYB61_RS11510 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) FYB61_RS11520 ENOG4105HBR Rna-binding protein FYB61_RS11530 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) FYB61_RS11535 ENOG4105C8Q Methyl-accepting chemotaxis FYB61_RS11540 ENOG4105C2W permease FYB61_RS11555 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FYB61_RS11565 ENOG4105CVJ phosphoglycerate mutase FYB61_RS11570 ENOG4105EMU Dehydrogenase FYB61_RS11585 ENOG4105F8V Hydrolase, tatD family FYB61_RS11590 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) FYB61_RS11605 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) FYB61_RS11615 ENOG410904N short-chain dehydrogenase reductase FYB61_RS11635 ENOG4108IQE Amp-dependent synthetase and ligase FYB61_RS11640 ENOG4108IV0 ABC, transporter FYB61_RS11650 ENOG4105CF8 branched-chain amino acid ABC transporter, permease FYB61_RS11660 ENOG4105C0Z ABC transporter FYB61_RS11665 ENOG4105CGU Enoyl-CoA hydratase FYB61_RS11675 ENOG4105WVQ Fe-S assembly protein IscX FYB61_RS11680 ENOG4108ZIT Ferredoxin, 2FE-2S FYB61_RS11695 ENOG4108Z4V iron-sulfur cluster assembly FYB61_RS11700 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins FYB61_RS11705 ENOG4105C3J Cysteine desulfurase FYB61_RS11725 ENOG4105CGF Aromatic amino acid aminotransferase FYB61_RS11735 ENOG4108P8G outer membrane autotransporter barrel FYB61_RS11745 ENOG4107QNJ CoA-transferase subunit B FYB61_RS11760 ENOG4105D2B acyl-CoA dehydrogenase FYB61_RS11765 ENOG4105CHR reductase FYB61_RS11770 ENOG4105CHU acetyl-coa acetyltransferase FYB61_RS11780 ENOG4108UKI Enoyl-CoA hydratase FYB61_RS11790 ENOG4105JN3 extra-cytoplasmic solute receptor family protein FYB61_RS11795 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F FYB61_RS11800 ENOG4105CN8 Transcriptional regulator FYB61_RS11805 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) FYB61_RS11815 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) FYB61_RS11825 ENOG4108TEB UPF0114 protein FYB61_RS11830 ENOG4105VEQ Cold shock protein FYB61_RS11840 ENOG4105VEQ Cold shock protein FYB61_RS11870 ENOG4105CHM Aminotransferase FYB61_RS11885 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) FYB61_RS11890 ENOG4105C5H ABC transporter FYB61_RS11895 ENOG4105PE1 Receptor FYB61_RS11900 ENOG4105C4R Atp-dependent dna helicase FYB61_RS11920 ENOG4108V3E phosphoribosylglycinamide formyltransferase FYB61_RS11925 ENOG4105DTN riboflavin biosynthesis protein ribF FYB61_RS11935 ENOG4105M02 This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity) FYB61_RS11940 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase FYB61_RS12000 ENOG4105CIF Ornithine Cyclodeaminase FYB61_RS12005 ENOG4108Z9K Osmotically inducible protein FYB61_RS12015 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) FYB61_RS12020 ENOG41080Z8 PHOSPHOCARRIER protein FYB61_RS12035 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) FYB61_RS12040 ENOG4105C22 threonyL-tRNA synthetase FYB61_RS12045 ENOG4108T94 DNA-binding transcriptional activator BglJ FYB61_RS12055 ENOG4105D4P Coproporphyrinogen iii oxidase FYB61_RS12105 ENOG4105CG6 trap dicarboxylate transporter dctm subunit FYB61_RS12115 ENOG4105CH5 extracellular solute-binding protein, family 7 FYB61_RS12130 ENOG4107QJH Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) FYB61_RS12155 ENOG4108JJB ABC transporter FYB61_RS12185 ENOG4105QAX Iron-sulfur FYB61_RS12190 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) FYB61_RS12225 ENOG4105C6R Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) FYB61_RS12230 ENOG4105CVM Molybdenum cofactor synthesis domain protein FYB61_RS12235 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b FYB61_RS12240 ENOG4105ERG peptidase m48, ste24p FYB61_RS12255 ENOG4105BZU Histidine kinase FYB61_RS12260 ENOG4106WF9 DNA-binding transcriptional regulator TorR FYB61_RS12275 ENOG4107S2Z UPF0761 membrane protein FYB61_RS12285 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) FYB61_RS12355 ENOG4105MWK D-amino acid dehydrogenase, small subunit FYB61_RS12400 ENOG4105CAX The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity) FYB61_RS12435 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) FYB61_RS12440 ENOG4105H1G trap transporter solute receptor taxi family FYB61_RS12455 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FYB61_RS12465 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FYB61_RS12470 ENOG4105K63 Thioredoxin FYB61_RS12475 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) FYB61_RS12490 ENOG4105WPN DNA integration recombination invertion protein FYB61_RS12495 ENOG4105EJQ L-serine dehydratase FYB61_RS12500 ENOG4105EAM Na Pi-cotransporter FYB61_RS12505 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) FYB61_RS12515 ENOG4105C2M dna polymerase I FYB61_RS12520 ENOG4108URH decarboxylase FYB61_RS12535 ENOG4105CI3 gtp-binding protein typa FYB61_RS12555 ENOG4105CHV Transcription elongation factor NusA FYB61_RS12565 ENOG4105FE9 pseudouridine synthase FYB61_RS12570 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) FYB61_RS12580 ENOG4105EJC lysr family transcriptional regulator FYB61_RS12590 ENOG4105CKI cobalamin synthesis protein FYB61_RS12610 ENOG4108RXX maleylacetoacetate isomerase FYB61_RS12615 ENOG4105C48 Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity) FYB61_RS12620 ENOG4108YZY peptidylprolyl cis-trans isomerase FYB61_RS12675 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) FYB61_RS12680 ENOG4105CP2 von willebrand factor, type a FYB61_RS12700 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) FYB61_RS12715 ENOG4105CVN desaturase FYB61_RS12715 ENOG4105CVN desaturase FYB61_RS12735 ENOG4105CJ1 ABC, transporter FYB61_RS12800 ENOG4108P8G outer membrane autotransporter barrel FYB61_RS12810 ENOG4105DS0 Transcriptional regulator, Crp Fnr family FYB61_RS12825 ENOG4108YZ4 nudix hydrolase FYB61_RS12830 ENOG4105VRT cytoplasmic protein FYB61_RS12840 ENOG4108KPJ rna polymerase sigma factor FYB61_RS12845 ENOG4105MDH Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) FYB61_RS12880 ENOG4105EAB amino acid AbC transporter FYB61_RS12885 ENOG4105EAD ABC transporter FYB61_RS12890 ENOG4105DRP amino acid AbC transporter FYB61_RS12920 ENOG4105Z2P Protein of unknown function (DUF465) FYB61_RS12925 ENOG4105D94 Major Facilitator Superfamily FYB61_RS12935 ENOG4105BZU Histidine kinase FYB61_RS12940 ENOG4105IPI Membrane FYB61_RS12945 ENOG4105E3A (ABC) transporter FYB61_RS12950 ENOG4105DA5 (ABC) transporter FYB61_RS12995 ENOG4105EUH cytochrome C oxidase, cbb3-type, subunit i FYB61_RS13010 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) FYB61_RS13025 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) FYB61_RS13030 ENOG4105VAW lrga family FYB61_RS13035 ENOG41067MG lrgb family FYB61_RS13060 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase FYB61_RS13080 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) FYB61_RS13085 ENOG4105ENJ RND efflux system, outer membrane lipoprotein FYB61_RS13095 ENOG4105C1P efflux transporter, rnd family, mfp subunit FYB61_RS13115 ENOG4105F4R Transcriptional regulator mode FYB61_RS13120 ENOG4105D5T phosphonate abc transporter FYB61_RS13135 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FYB61_RS13145 ENOG4105CEY Amp-dependent synthetase and ligase FYB61_RS13150 ENOG4105E39 Enoyl-CoA hydratase FYB61_RS13160 ENOG4105DRR Transcriptional regulator, GntR family FYB61_RS13170 ENOG4105CHU acetyl-coa acetyltransferase FYB61_RS13180 ENOG4108IJ7 Glycine betaine FYB61_RS13185 ENOG4108HQS Glycine betaine FYB61_RS13195 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase FYB61_RS13200 ENOG4105C2C drug resistance transporter, Bcr CflA FYB61_RS13205 ENOG4105KDC 50s ribosomal protein l28 FYB61_RS13210 ENOG4105W0E 50S ribosomal protein L33 FYB61_RS13225 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes FYB61_RS13260 ENOG4105EUF amidase EC 3.5.1.4 FYB61_RS13265 ENOG4105F35 Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity) FYB61_RS13305 ENOG4105C03 ribonuclease FYB61_RS13310 ENOG4105CQC Prephenate dehydratase FYB61_RS13330 ENOG4105XA0 heptosyltransferase ii FYB61_RS13340 ENOG4105KRS Proteinase inhibitor FYB61_RS13355 ENOG4105DIJ Phosphoethanolamine transferase FYB61_RS13360 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) FYB61_RS13365 ENOG4106WTF Glycosyl transferase, family 2 FYB61_RS13370 ENOG4107BJW polysaccharide deacetylase FYB61_RS13375 ENOG4105CPK Glycosyl transferase (Group 1 FYB61_RS13380 ENOG4105C0B DNA polymerase III (alpha subunit) FYB61_RS13390 ENOG4105CQ7 ATP-dependent helicase FYB61_RS13395 ENOG4108EKC n-acetylglutamate synthase FYB61_RS13400 ENOG4105KMG Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity) FYB61_RS13405 ENOG4105HSS phospholipase C FYB61_RS13410 ENOG4108UTW Plays a role in the regulation of phosphate uptake FYB61_RS13420 ENOG4105CSU acyl-Coa dehydrogenase FYB61_RS13445 ENOG4105D38 putrescine abc transporter FYB61_RS13450 ENOG4105F38 ABC transporter, permease FYB61_RS13455 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FYB61_RS13460 ENOG4107RUE extracellular solute-binding protein family 1 FYB61_RS13475 ENOG4105CV6 ABC transporter, permease FYB61_RS13480 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit FYB61_RS13490 ENOG4105CG6 trap dicarboxylate transporter dctm subunit FYB61_RS13495 ENOG4105X0I Fimbrial FYB61_RS13500 ENOG4105X0I Fimbrial FYB61_RS13515 ENOG4108ZJI phenylacetic acid degradation protein FYB61_RS13520 ENOG4108UKI Enoyl-CoA hydratase FYB61_RS13530 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) FYB61_RS13535 ENOG4108ZA2 phenylacetate-CoA oxygenase PaaJ subunit FYB61_RS13540 ENOG4105D9S phenylacetate-CoA oxygenase PaaI subunit FYB61_RS13545 ENOG4105N76 Phenylacetate-CoA oxygenase, subunit FYB61_RS13550 ENOG4105CRS phenylacetate-CoA oxygenase PaaG subunit FYB61_RS13565 ENOG4108RBP 3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity) FYB61_RS13570 ENOG4105D0M Protease HtpX homolog FYB61_RS13575 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) FYB61_RS13580 ENOG4105CPC Aldo Keto reductase FYB61_RS13585 ENOG4105P8F nudix hydrolase FYB61_RS13590 ENOG4108YY1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity) FYB61_RS13610 ENOG4105C3T may be the GTPase, regulating ATP sulfurylase activity (By similarity) FYB61_RS13630 ENOG4105ECW sulfate abc transporter FYB61_RS13635 ENOG4108I5D sulfate abc transporter FYB61_RS13650 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) FYB61_RS13660 ENOG4105CH5 extracellular solute-binding protein, family 7 FYB61_RS13665 ENOG4108S8N class II Aldolase FYB61_RS13690 ENOG4105Y49 secretion protein, HlyD family FYB61_RS13700 ENOG4106KED esterase YpfH FYB61_RS13725 ENOG4105KPV Transcriptional regulator FYB61_RS13740 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) FYB61_RS13760 ENOG4108JQC penicillin-binding protein 1A FYB61_RS13765 ENOG4108R1E Serine threonine protein phosphatase 1 FYB61_RS13780 ENOG4105CPC Aldo Keto reductase FYB61_RS13790 ENOG4108JJ7 ABC transporter FYB61_RS13820 ENOG4108P8G outer membrane autotransporter barrel FYB61_RS13825 ENOG4108P8G outer membrane autotransporter barrel FYB61_RS13845 ENOG4105BZU Histidine kinase FYB61_RS13850 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor FYB61_RS13855 ENOG4108M8H domain protein FYB61_RS13860 ENOG4108Z7R Chaperone CsaA FYB61_RS13890 ENOG4105DDW LysR family Transcriptional regulator FYB61_RS13895 ENOG4105CHR reductase FYB61_RS13900 ENOG4105C0R drug resistance transporter emrb qaca subfamily FYB61_RS13925 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase FYB61_RS13940 ENOG4105EE5 Membrane protein terC FYB61_RS13955 ENOG4108Q6X Aspartoacylase (EC 3.5.1.15) FYB61_RS13975 ENOG4105BZU Histidine kinase FYB61_RS13980 ENOG4108ZCF integral membrane protein FYB61_RS13990 ENOG4105EMN RNA polymerase sigma factor FYB61_RS13995 ENOG4105BZU Histidine kinase FYB61_RS14020 ENOG4105K78 MarR family Transcriptional regulator FYB61_RS14050 ENOG4105C7K acetolactate synthase FYB61_RS14055 ENOG4105CE7 Amidase, hydantoinase carbamoylase family FYB61_RS14060 ENOG4105C26 Dehydrogenase FYB61_RS14065 ENOG4105D82 Glutamate dehydrogenase FYB61_RS14075 ENOG4105CDA abc transporter atp-binding protein FYB61_RS14100 ENOG4105F8V Hydrolase, tatD family FYB61_RS14105 ENOG4105C6E dna polymerase iii FYB61_RS14110 ENOG4108ZMD Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity) FYB61_RS14115 ENOG4105HHA aminodeoxychorismate lyase FYB61_RS14120 ENOG4106XY2 Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity) FYB61_RS14135 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase FYB61_RS14140 ENOG4108IPT Naphthoate synthase FYB61_RS14145 ENOG4105C1G acyl-Coa dehydrogenase FYB61_RS14155 ENOG4108Z1B Cyclase dehydrase FYB61_RS14170 ENOG4107QX8 SPFH domain, Band 7 family protein FYB61_RS14185 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) FYB61_RS14200 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) FYB61_RS14225 ENOG4108RFI Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity) FYB61_RS14230 ENOG4105E1Z Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane FYB61_RS14235 ENOG4105DZP Membrane-associated zinc metalloprotease FYB61_RS14245 ENOG4105KNE Phosphatidate cytidylyltransferase FYB61_RS14250 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) FYB61_RS14255 ENOG4108VCV Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity) FYB61_RS14270 ENOG4105CE9 30S ribosomal protein S2 FYB61_RS14275 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) FYB61_RS14295 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase FYB61_RS14310 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase FYB61_RS14320 ENOG4105DTS flagellar hook-associated FYB61_RS14325 ENOG4105MQ3 flagellar protein FliS FYB61_RS14340 ENOG4105D00 flagellar biosynthetic protein flhB FYB61_RS14350 ENOG4105VQ0 flagellar hook-basal body complex protein fliE FYB61_RS14360 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) FYB61_RS14365 ENOG4108CG0 Flagellar assembly protein FYB61_RS14370 ENOG4108JIR Flagellum-specific ATP synthase FYB61_RS14385 ENOG4107ZI8 flagellar basal body-associated protein flil FYB61_RS14390 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) FYB61_RS14405 ENOG4105CN7 Flagellar biosynthetic protein FliP FYB61_RS14410 ENOG4105VS8 Flagellar biosynthetic protein fliq FYB61_RS14425 ENOG4105C8Q Methyl-accepting chemotaxis FYB61_RS14430 ENOG4105DTJ flagellar hook-associated protein FYB61_RS14435 ENOG4105E1Q flagellar hook-associated protein FYB61_RS14440 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj FYB61_RS14460 ENOG4108KPB Flagellar basal-body rod protein FlgF FYB61_RS14465 ENOG4105BZE flagellar hook protein, FlgE FYB61_RS14470 ENOG4105W00 Flagellar hook capping protein FYB61_RS14475 ENOG4108ZC9 flagellar basal-body rod protein flgc FYB61_RS14480 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) FYB61_RS14490 ENOG4105M9M anti-sigma28 factor FlgM FYB61_RS14510 ENOG4105D00 flagellar biosynthetic protein flhB FYB61_RS14515 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) FYB61_RS14520 ENOG4108VYJ response regulator receiver protein FYB61_RS14530 ENOG4105BZU Histidine kinase FYB61_RS14535 ENOG4105C8Q Methyl-accepting chemotaxis FYB61_RS14540 ENOG4108V3W Chemotaxis protein, CheW FYB61_RS14545 ENOG4105CBS Chea signal transduction histidine kinase FYB61_RS14550 ENOG4108VYJ response regulator receiver protein FYB61_RS14555 ENOG4105ER2 Ompa motb domain protein FYB61_RS14560 ENOG4107RD7 Flagellar Motor Protein, MotA FYB61_RS14565 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region FYB61_RS14570 ENOG4105GEH Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways (By similarity) FYB61_RS14580 ENOG4105I03 Flagellin FYB61_RS14585 ENOG4107QN2 dihydrolipoyl dehydrogenase FYB61_RS14590 ENOG4107QSN dihydrolipoamide acetyltransferase FYB61_RS14595 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) FYB61_RS14600 ENOG4105BZU Histidine kinase FYB61_RS14605 ENOG4108ZXC Two component transcriptional regulator, luxr family FYB61_RS14610 ENOG4105CN0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity) FYB61_RS14615 ENOG4105DGW oligopeptidase A FYB61_RS14630 ENOG4105ENJ RND efflux system, outer membrane lipoprotein FYB61_RS14635 ENOG4105BZS acriflavin resistance protein FYB61_RS14640 ENOG4105C1P efflux transporter, rnd family, mfp subunit FYB61_RS14645 ENOG4105JQN Transcriptional regulator FYB61_RS14650 ENOG4105FE9 pseudouridine synthase FYB61_RS14655 ENOG4105RUM Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity) FYB61_RS14665 ENOG4108VWS Yaeq family FYB61_RS14670 ENOG4105N14 lysine exporter protein LysE YggA FYB61_RS14680 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FYB61_RS14685 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component FYB61_RS14690 ENOG4105DEF Extracellular solute-binding protein, family 5 FYB61_RS14695 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) FYB61_RS14700 ENOG4105DUM transcriptional regulator, lysR family FYB61_RS14715 ENOG4105VEJ Heat shock protein FYB61_RS14725 ENOG4108YZA Nitrogen regulatory protein pii FYB61_RS14735 ENOG4105CUY Mechanosensitive ion channel FYB61_RS14740 ENOG4105CH7 arginosuccinase FYB61_RS14750 ENOG4105W1Y Transcriptional regulator FYB61_RS14765 ENOG4105E5Q amino acid AbC transporter FYB61_RS14770 ENOG4105CDA abc transporter atp-binding protein FYB61_RS14780 ENOG4105VIG Sec-independent protein translocase protein TatC FYB61_RS14840 ENOG4108UAU isochorismatase FYB61_RS14845 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit FYB61_RS14855 ENOG4105CG6 trap dicarboxylate transporter dctm subunit FYB61_RS14865 ENOG4105EZR dyp-type peroxidase family protein FYB61_RS14930 ENOG4105DDW LysR family Transcriptional regulator FYB61_RS14935 ENOG4105DXI Major Facilitator superfamily FYB61_RS14945 ENOG4108K0D peptidase, M48 FYB61_RS14950 ENOG4105CHR reductase FYB61_RS14955 ENOG4105CBN LysR family transcriptional regulator FYB61_RS14965 ENOG4105FDP GntR family transcriptional regulator FYB61_RS14980 ENOG4107Z6I Thiamine biosynthesis protein FYB61_RS14995 ENOG4105C01 Dihydroxy-acid dehydratase FYB61_RS15010 ENOG4105C01 Dihydroxy-acid dehydratase FYB61_RS15015 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase FYB61_RS15020 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) FYB61_RS15025 ENOG4105EXW epimerase dehydratase FYB61_RS15030 ENOG4105CH5 extracellular solute-binding protein, family 7 FYB61_RS15040 ENOG4105CG6 trap dicarboxylate transporter dctm subunit FYB61_RS15045 ENOG4107RSM transcriptional regulator FYB61_RS15050 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase FYB61_RS15105 ENOG4105CYM Glutathione S-transferase FYB61_RS15120 ENOG4105DC8 reductase FYB61_RS15125 ENOG4105N14 lysine exporter protein LysE YggA FYB61_RS15130 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) FYB61_RS15140 ENOG4105EXG Transcriptional regulator FYB61_RS15165 ENOG4105CF7 AraC family transcriptional regulator FYB61_RS15200 ENOG4105XYF acetyltransferase FYB61_RS15205 ENOG4105BZ1 (ABC) transporter FYB61_RS15230 ENOG4105CHH sulfate transporter FYB61_RS15265 ENOG4105KCV RNA signal recognition particle 4.5S RNA FYB61_RS15270 ENOG4107ZY0 Phenazine biosynthesis-like protein FYB61_RS15275 ENOG4105SKE transcriptional Regulator LysR family FYB61_RS15280 ENOG4106BRA Membrane FYB61_RS15295 ENOG4105C26 Dehydrogenase FYB61_RS15300 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family FYB61_RS15305 ENOG4105CV8 reductase FYB61_RS15330 ENOG4107QWP ABC-2 type transporter FYB61_RS15350 ENOG4105DRR Transcriptional regulator, GntR family FYB61_RS15355 ENOG4105II7 pyrroline-5-carboxylate reductase FYB61_RS15365 ENOG4105DG4 malate L-lactate dehydrogenase FYB61_RS15375 ENOG4108TZY GntR Family Transcriptional Regulator FYB61_RS15400 ENOG4108Z4X TRANSCRIPTIONal FYB61_RS15415 ENOG4105ETE Transcriptional regulator (LacI family FYB61_RS15420 ENOG4108JQ6 ABC transporter FYB61_RS15435 ENOG4105DEF Extracellular solute-binding protein, family 5 FYB61_RS15450 ENOG410829K Lysine exporter protein (Lyse ygga) FYB61_RS15485 ENOG4105C26 Dehydrogenase FYB61_RS15490 ENOG4108PGP mmge prpd family protein FYB61_RS15495 ENOG4105GAK amidohydrolase 2 FYB61_RS15510 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F FYB61_RS15530 ENOG4105JN3 extra-cytoplasmic solute receptor family protein FYB61_RS15540 ENOG4105CY0 Metallo-Beta-Lactamase FYB61_RS15555 ENOG4105CYM Glutathione S-transferase FYB61_RS15595 ENOG4105ECI YeeC-like protein FYB61_RS15600 ENOG4105F6A helicase FYB61_RS15625 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) FYB61_RS15640 ENOG4105WH1 Two component transcriptional regulator luxr family FYB61_RS15645 ENOG4105C77 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity) FYB61_RS15660 ENOG4108KHN disulfide isomerase, thiol-disulfide oxidase FYB61_RS15665 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen FYB61_RS15705 ENOG4108QZZ filamentous hemagglutinin FYB61_RS15710 ENOG4108ETH Formylglycinamide ribotide synthetase FYB61_RS15715 ENOG4105XDZ Tripartite ATP-independent periplasmic transporter FYB61_RS15720 ENOG4105CG6 trap dicarboxylate transporter dctm subunit FYB61_RS15735 ENOG4105DB7 PHP domain protein FYB61_RS15755 ENOG4108YZN class I peptide chain release factor FYB61_RS15765 ENOG4105D3R alkyl hydroperoxide reductase FYB61_RS15770 ENOG4105CSU acyl-Coa dehydrogenase FYB61_RS15775 ENOG4105C10 Electron transfer flavoprotein FYB61_RS15780 ENOG4105BZJ Electron transfer flavoprotein FYB61_RS15790 ENOG4105CVE Lytic murein transglycosylase FYB61_RS15795 ENOG4105C6T cysteine synthase FYB61_RS15810 ENOG4105DW0 Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity) FYB61_RS15815 ENOG4105CFV Tetratricopeptide repeat protein FYB61_RS15830 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) FYB61_RS15845 ENOG4105EVN Prephenate dehydrogenase FYB61_RS15860 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FYB61_RS15865 ENOG4105UYK outer membrane protein a FYB61_RS15875 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) FYB61_RS15880 ENOG4105F27 Major Facilitator FYB61_RS15910 ENOG4105JN3 extra-cytoplasmic solute receptor family protein FYB61_RS15945 ENOG4105DDW LysR family Transcriptional regulator FYB61_RS15960 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase FYB61_RS15980 ENOG41079YP Citrate utilization protein b FYB61_RS15985 ENOG4107EFR Flavocytochrome c FYB61_RS15990 ENOG4105C26 Dehydrogenase FYB61_RS15995 ENOG4105DXD 2-methylcitrate dehydratase FYB61_RS16005 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component FYB61_RS16030 ENOG4105DTI Phosphonopyruvate decarboxylase FYB61_RS16055 ENOG4108DBC nitroreductase FYB61_RS16060 ENOG4105C0R drug resistance transporter emrb qaca subfamily FYB61_RS16065 ENOG4105BZU Histidine kinase FYB61_RS16080 ENOG4105CVE Lytic murein transglycosylase FYB61_RS16085 ENOG4105ED9 Protein of unknown function (DUF455) FYB61_RS16100 ENOG4105BZ1 (ABC) transporter FYB61_RS16115 ENOG4105VDW Csbd family FYB61_RS16125 ENOG4105K3G Periplasmic Protein FYB61_RS16135 ENOG4105JAB phenazine biosynthesis protein, phzf family FYB61_RS16145 ENOG4105EKT )-iron permease FYB61_RS16160 ENOG4108NVM synthesis repressor PhaR FYB61_RS16165 ENOG4105CHR reductase FYB61_RS16170 ENOG4105D1N poly(r)-hydroxyalkanoic acid synthase, class FYB61_RS16175 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase FYB61_RS16180 ENOG4105C34 Pseudouridine synthase FYB61_RS16190 ENOG4105DVT helicase FYB61_RS16195 ENOG4105BZM domain protein FYB61_RS16220 ENOG4105E0K tonB-dependent siderophore receptor FYB61_RS16230 ENOG4108SF5 RNA Polymerase FYB61_RS16240 ENOG4105CHR reductase FYB61_RS16250 ENOG4107RSM transcriptional regulator FYB61_RS16255 ENOG4105CHR reductase FYB61_RS16260 ENOG4105D6Z AFG1 family ATPase FYB61_RS16265 ENOG4107QN2 dihydrolipoyl dehydrogenase FYB61_RS16270 ENOG4105C7S Dehydrogenase FYB61_RS16275 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 FYB61_RS16285 ENOG4108YXU transcriptional regulator AsnC family FYB61_RS16290 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) FYB61_RS16295 ENOG4105C6K Malic enzyme FYB61_RS16300 ENOG4105X0I Fimbrial FYB61_RS16315 ENOG4105BZN citrate synthase FYB61_RS16320 ENOG41060IS Flavinator of succinate dehydrogenase FYB61_RS16325 ENOG4105E33 succinate dehydrogenase FYB61_RS16335 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein FYB61_RS16340 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit FYB61_RS16345 ENOG4105FDP GntR family transcriptional regulator FYB61_RS16350 ENOG4105D9Z Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) FYB61_RS16355 ENOG4105CR4 methylisocitrate lyase FYB61_RS16360 ENOG4105BZN citrate synthase FYB61_RS16365 ENOG4108I0Z Aconitate hydratase FYB61_RS16370 ENOG4105C7F AcnD-accessory protein PrpF FYB61_RS16375 ENOG4105DXD 2-methylcitrate dehydratase FYB61_RS16380 ENOG4108YXA Membrane FYB61_RS16405 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) FYB61_RS16415 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) FYB61_RS16450 ENOG4105C70 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity) FYB61_RS16460 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase FYB61_RS16465 ENOG4105C8D Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity) FYB61_RS16485 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FYB61_RS16495 ENOG4105DEF Extracellular solute-binding protein, family 5 FYB61_RS16500 ENOG4108JQ6 ABC transporter FYB61_RS16505 ENOG4105D44 asparaginase FYB61_RS16530 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase FYB61_RS16535 ENOG4105CMR udp-glucose 4-epimerase FYB61_RS16550 ENOG4105C5W Aldolase FYB61_RS16555 ENOG4108Q5Y Membrane FYB61_RS16560 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) FYB61_RS16570 ENOG4108ZJF Glcg protein FYB61_RS16575 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) FYB61_RS16580 ENOG4105K4H Nlp p60 protein FYB61_RS16590 ENOG4107R11 Transcriptional regulator FYB61_RS16595 ENOG4105C26 Dehydrogenase FYB61_RS16605 ENOG410825D TRANSCRIPTIONal REGULATOR, LysR family FYB61_RS16620 ENOG4105MYG DNA polymerase iii, chi subunit FYB61_RS16630 ENOG4108MN8 Membrane FYB61_RS16655 ENOG41071DT Involved in DNA repair and RecF pathway recombination (By similarity) FYB61_RS16660 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) FYB61_RS16665 ENOG4108ZBM Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity) FYB61_RS16670 ENOG4105C3F Signal peptidase i FYB61_RS16680 ENOG4105C0H protease FYB61_RS16695 ENOG4105EMN RNA polymerase sigma factor FYB61_RS16705 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) FYB61_RS16710 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) FYB61_RS16715 ENOG4105CHR reductase FYB61_RS16720 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase FYB61_RS16735 ENOG4105VGS 50s ribosomal protein l32 FYB61_RS16740 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein FYB61_RS16750 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) FYB61_RS16755 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase FYB61_RS16765 ENOG4105CCD The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity) FYB61_RS16770 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) FYB61_RS16775 ENOG4105EI2 Pseudouridine synthase FYB61_RS16780 ENOG4105C03 ribonuclease FYB61_RS16790 ENOG41061N2 exported protein FYB61_RS16795 ENOG4107QTG Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity) FYB61_RS16820 ENOG4105EXZ Involved in the regulation of ptsG expression by binding and inactivating Mlc (By similarity) FYB61_RS16830 ENOG4105M4H endoribonuclease L-psp FYB61_RS16840 ENOG4108Z4U Ferredoxin FYB61_RS16845 ENOG4105DP0 ferredoxin-NADP reductase FYB61_RS16855 ENOG4108R3D Electron transport complex FYB61_RS16860 ENOG4105CSM endonuclease III FYB61_RS16865 ENOG4105C0Z ABC transporter FYB61_RS16870 ENOG4108IV0 ABC, transporter FYB61_RS16880 ENOG4105C32 Amino acid ABC transporter (Permease) FYB61_RS16895 ENOG4105CM2 brancheD-chain amino acid aminotransferase FYB61_RS16900 ENOG4108IV0 ABC, transporter FYB61_RS16905 ENOG4105C0Z ABC transporter FYB61_RS16920 ENOG4107ZYJ bioY protein FYB61_RS16925 ENOG4107QCX Transporter FYB61_RS16930 ENOG4108JJB ABC transporter FYB61_RS16935 ENOG4105E0X reductase FYB61_RS16945 ENOG4105M85 Bola protein FYB61_RS16950 ENOG4107TF3 peptidylprolyl cis-trans isomerase FYB61_RS16965 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) FYB61_RS16970 ENOG4108J8Q Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity) FYB61_RS16975 ENOG4108UN4 phage SPO1 DNA polymerase-related protein FYB61_RS16980 ENOG41072GX Peptidase M22 Glycoprotease FYB61_RS16990 ENOG4105E0F Histidine kinase FYB61_RS16995 ENOG4105D3R alkyl hydroperoxide reductase FYB61_RS17000 ENOG4108X7C Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) FYB61_RS17015 ENOG4108UH8 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity) FYB61_RS17025 ENOG4108JA2 transcriptioN-repair coupling factor FYB61_RS17030 ENOG4105EAC phosphoserine phosphatase FYB61_RS17035 ENOG4105F04 LysR family Transcriptional regulator FYB61_RS17045 ENOG4105C7K acetolactate synthase FYB61_RS17050 ENOG4105CHR reductase FYB61_RS17070 ENOG4108ESX Receptor FYB61_RS17080 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) FYB61_RS17085 ENOG4105C8S subunit m FYB61_RS17095 ENOG4105M5H NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) FYB61_RS17100 ENOG4105DF2 NADH dehydrogenase subunit j FYB61_RS17105 ENOG4105P3U NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) FYB61_RS17110 ENOG4105CMZ NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity) FYB61_RS17115 ENOG4108IEH NADH dehydrogenase subunit g FYB61_RS17140 ENOG4105ES3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) FYB61_RS17145 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain FYB61_RS17150 ENOG4108Z9W Outer membrane porin FYB61_RS17170 ENOG410841Q phosphoesterase PA-phosphatase related protein FYB61_RS17180 ENOG4105CBD Diacylglycerol kinase FYB61_RS17185 ENOG4105DUM transcriptional regulator, lysR family FYB61_RS17190 ENOG4105C94 Transporter FYB61_RS17195 ENOG4105KVH Transcriptional regulator FYB61_RS17200 ENOG4105ENT Efflux transporter rnd family, mfp subunit FYB61_RS17210 ENOG4105ENJ RND efflux system, outer membrane lipoprotein FYB61_RS17220 ENOG41090JD Blue (Type 1) copper domain protein FYB61_RS17240 ENOG4105CJP fad dependent oxidoreductase FYB61_RS17260 ENOG4105E5N succinylglutamate desuccinylase aspartoacylase FYB61_RS17265 ENOG4105C28 cystathionine FYB61_RS17270 ENOG4107NQ8 LysR family Transcriptional regulator FYB61_RS17275 ENOG4107EXU Short-chain dehydrogenase reductase Sdr FYB61_RS17285 ENOG4105CH7 arginosuccinase FYB61_RS17300 ENOG4105DV9 Methylaspartate ammonia-lyase FYB61_RS17310 ENOG4105C94 Transporter FYB61_RS17320 ENOG4105NTZ Preprotein translocase subunit SecG FYB61_RS17325 ENOG4105CP7 Triose-phosphate isomerase FYB61_RS17345 ENOG4105C7B Threonine dehydratase FYB61_RS17355 ENOG4105C62 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity) FYB61_RS17360 ENOG4105K77 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity) FYB61_RS17370 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase FYB61_RS17380 ENOG4108ZP8 Acetolactate synthase small subunit FYB61_RS17385 ENOG4105C7K acetolactate synthase FYB61_RS17400 ENOG4105D1Q UPF0246 protein FYB61_RS17405 ENOG4105DTD Dehydrogenase FYB61_RS17410 ENOG4105CKD glutathione-regulated potassium-efflux system protein FYB61_RS17420 ENOG4105F1Y L-lysine 6-monooxygenase (NADPH) FYB61_RS17450 ENOG4108RWP Major Facilitator Superfamily protein FYB61_RS17455 ENOG4105CNM Receptor FYB61_RS17470 ENOG4105BZU Histidine kinase FYB61_RS17505 ENOG4105D1H recombination factor protein RarA FYB61_RS17515 ENOG4105CNU cell division protein FtsK FYB61_RS17520 ENOG4105C3M thioredoxin reductase FYB61_RS17525 ENOG4105C98 muts2 protein FYB61_RS17535 ENOG4107QN1 sodium solute FYB61_RS17555 ENOG4105C8X One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) FYB61_RS17560 ENOG4108R80 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity) FYB61_RS17565 ENOG4105C08 Histidine kinase FYB61_RS17570 ENOG4105EEX Two component transcriptional regulator (Winged helix family FYB61_RS17605 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) FYB61_RS17645 ENOG4105K90 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ FYB61_RS17660 ENOG4105CI8 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity) FYB61_RS17670 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) FYB61_RS17680 ENOG41090R7 Ferric uptake FYB61_RS17685 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) FYB61_RS17730 ENOG4105D43 The glycine cleavage system catalyzes the degradation of glycine (By similarity) FYB61_RS17735 ENOG4105WIU sarcosine oxidase delta subunit FYB61_RS17740 ENOG4105DDR sarcosine oxidase (Beta subunit) FYB61_RS17750 ENOG4108M0I Transcriptional regulator FYB61_RS17755 ENOG4105DG4 malate L-lactate dehydrogenase FYB61_RS17765 ENOG4105JN3 extra-cytoplasmic solute receptor family protein FYB61_RS17770 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F FYB61_RS17775 ENOG4105DJG MaoC domain protein dehydratase FYB61_RS17785 ENOG4105CGU Enoyl-CoA hydratase FYB61_RS17810 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit FYB61_RS17820 ENOG4105CG6 trap dicarboxylate transporter dctm subunit FYB61_RS17835 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase FYB61_RS17850 ENOG4105CJP fad dependent oxidoreductase FYB61_RS17860 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) FYB61_RS17870 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein FYB61_RS17875 ENOG410829K Lysine exporter protein (Lyse ygga) FYB61_RS17905 ENOG4105CC0 LysR family Transcriptional regulator FYB61_RS17945 ENOG41069M3 Transcriptional regulator FYB61_RS17950 ENOG4107TH8 cina domain protein FYB61_RS17965 ENOG4105C1J atp-dependent rna helicase FYB61_RS17980 ENOG4105CM2 brancheD-chain amino acid aminotransferase FYB61_RS17995 ENOG4105DNZ Alpha Beta Hydrolase FYB61_RS18000 ENOG4105ERG peptidase m48, ste24p FYB61_RS18015 ENOG4108Z9W Outer membrane porin FYB61_RS18030 ENOG4107RAQ aminopeptidase FYB61_RS18040 ENOG4105D0A hydroxylase FYB61_RS18045 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) FYB61_RS18085 ENOG4105C9U ATP-dependent DNA helicase RecQ FYB61_RS18110 ENOG4105C4M (Ubiquinol oxidase) subunit I FYB61_RS18125 ENOG4107QMS site-determining protein FYB61_RS18130 ENOG4105VJP Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity) FYB61_RS18145 ENOG4105C5H ABC transporter FYB61_RS18170 ENOG4108JQ7 (ABC) transporter FYB61_RS18175 ENOG4105C3U ABC transporter FYB61_RS18180 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FYB61_RS18195 ENOG4108SHN Glycosyl transferase, family 2 FYB61_RS18205 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) FYB61_RS18230 ENOG4105CEY Amp-dependent synthetase and ligase FYB61_RS18235 ENOG4105FDP GntR family transcriptional regulator FYB61_RS18240 ENOG4105CUZ uba thif-type nad fad binding protein FYB61_RS18255 ENOG4108S7T Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity) FYB61_RS18275 ENOG4107RSM transcriptional regulator FYB61_RS18280 ENOG4105CSU acyl-Coa dehydrogenase FYB61_RS18290 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F FYB61_RS18295 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) FYB61_RS18320 ENOG4105K8N protein family UPF0079, ATPase FYB61_RS18325 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase FYB61_RS18330 ENOG4105DQR SNARE associated Golgi FYB61_RS18350 ENOG4108KZ1 Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity) FYB61_RS18360 ENOG4105DJ0 Poly(A) Polymerase FYB61_RS18365 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase FYB61_RS18380 ENOG4105CG6 trap dicarboxylate transporter dctm subunit FYB61_RS18385 ENOG4105CH5 extracellular solute-binding protein, family 7 FYB61_RS18390 ENOG4105FDP GntR family transcriptional regulator FYB61_RS18400 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase FYB61_RS18405 ENOG4107XDQ Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) FYB61_RS18420 ENOG4108R85 Short chain dehydrogenase FYB61_RS18430 ENOG4108MGF sugar kinase FYB61_RS18435 ENOG4105CI0 Citrate lyase FYB61_RS18445 ENOG4108M9J MaoC like domain protein FYB61_RS18465 ENOG4105FDP GntR family transcriptional regulator FYB61_RS18470 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) FYB61_RS18475 ENOG4105MQS Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) FYB61_RS18490 ENOG4108HMW glycyl-tRNA synthetase, alpha subunit FYB61_RS18495 ENOG4105C38 Glycyl-tRNA synthetase beta subunit FYB61_RS18500 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase FYB61_RS18505 ENOG4105E9Q Acyl-transferase FYB61_RS18520 ENOG4108RBJ Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) FYB61_RS18525 ENOG4107QPN acyl-Coa dehydrogenase FYB61_RS18535 ENOG4105CA9 Pyruvate kinase FYB61_RS18560 ENOG4105EHM Aminoglycoside phosphotransferase FYB61_RS18565 ENOG4108S0S Nucleotidyl transferase FYB61_RS18575 ENOG4105KZX Pterin carbinolamine dehydratase FYB61_RS18595 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) FYB61_RS18600 ENOG4105EUF amidase EC 3.5.1.4 FYB61_RS18635 ENOG4105D3D Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine (By similarity) FYB61_RS18650 ENOG4108S3W Anti-feci sigma factor, fecr FYB61_RS18655 ENOG4105E0K tonB-dependent siderophore receptor FYB61_RS18660 ENOG4108YYC ycei family FYB61_RS18665 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) FYB61_RS18680 ENOG4105ETT transcriptional Regulator, LysR family FYB61_RS18705 ENOG4105ERH Fumarylacetoacetate hydrolase FYB61_RS18735 ENOG4105F6U Short-chain dehydrogenase reductase Sdr FYB61_RS18740 ENOG4108XFH Transcriptional regulator FYB61_RS18745 ENOG41066T0 asmA family FYB61_RS18750 ENOG4108R3E Dna-3-methyladenine glycosylase i FYB61_RS18755 ENOG4108Z4X TRANSCRIPTIONal FYB61_RS18770 ENOG4105WEM extracellular solute-binding protein FYB61_RS18775 ENOG4105DX1 Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity) FYB61_RS18780 ENOG4108IJ9 (ABC) transporter FYB61_RS18785 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component FYB61_RS18810 ENOG41073TP transcriptional regulator FYB61_RS18830 ENOG4105C0A alcohol dehydrogenase FYB61_RS18840 ENOG4105D01 (LipO)protein FYB61_RS18845 ENOG4108UMI ABC transporter, permease FYB61_RS18850 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) FYB61_RS18855 ENOG4105CJQ hydrolase, family 31 FYB61_RS18865 ENOG4105ECY inositol monophosphatase FYB61_RS18870 ENOG4105CEY Amp-dependent synthetase and ligase FYB61_RS18875 ENOG4105CH2 amidohydrolase FYB61_RS18880 ENOG4105DUM transcriptional regulator, lysR family FYB61_RS18885 ENOG4105HMI Membrane FYB61_RS18890 ENOG4105NAU thioesterase Superfamily protein FYB61_RS18895 ENOG4105CJW magnesium transporter FYB61_RS18910 ENOG4108XM1 transcriptional regulator AsnC family FYB61_RS18915 ENOG4105MWK D-amino acid dehydrogenase, small subunit FYB61_RS18920 ENOG4105CHR reductase FYB61_RS18945 ENOG4105DR5 peptidase FYB61_RS18955 ENOG4105C7C involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) FYB61_RS18960 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) FYB61_RS18965 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) FYB61_RS18970 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) FYB61_RS19000 ENOG4105CPY First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity) FYB61_RS19005 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) FYB61_RS19010 ENOG4105CJN penicillin-binding protein FYB61_RS19015 ENOG4105N8N Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) FYB61_RS19020 ENOG4105CGJ Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity) FYB61_RS19025 ENOG4108V6E Cell division protein mraZ FYB61_RS19035 ENOG4105C5H ABC transporter FYB61_RS19040 ENOG4105EKE dihydroorotase FYB61_RS19045 ENOG4105CH2 amidohydrolase FYB61_RS19085 ENOG4105EW9 transcriptional regulator AsnC family FYB61_RS19090 ENOG4105E6K 4-Hydroxyphenylpyruvate dioxygenase FYB61_RS19095 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) FYB61_RS19100 ENOG4105W2Z cytochrome C, class I FYB61_RS19150 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) FYB61_RS19155 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase FYB61_RS19165 ENOG4105EXG Transcriptional regulator FYB61_RS19200 ENOG4107YD3 Thioesterase FYB61_RS19205 ENOG4105E02 MotA TolQ exbB proton channel FYB61_RS19225 ENOG4105KCK Peptidoglycan-associated lipoprotein FYB61_RS19235 ENOG4105EHG Permease protein FYB61_RS19255 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes FYB61_RS19260 ENOG4108DN8 FAD dependent oxidoreductase FYB61_RS19275 ENOG4105JN3 extra-cytoplasmic solute receptor family protein FYB61_RS19285 ENOG4105CHU acetyl-coa acetyltransferase FYB61_RS19295 ENOG4105CC9 acyl-Coa dehydrogenase FYB61_RS19300 ENOG4106NZI LysR family Transcriptional regulator FYB61_RS19310 ENOG4105E39 Enoyl-CoA hydratase FYB61_RS19315 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F FYB61_RS19320 ENOG4105EE5 Membrane protein terC FYB61_RS19325 ENOG4108302 MgtC SapB transporter FYB61_RS19350 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FYB61_RS19355 ENOG4105T38 integral membrane protein FYB61_RS19365 ENOG4107XM9 (LipO)protein FYB61_RS19400 ENOG4105D6U Sodium Glutamate Symporter FYB61_RS19410 ENOG4105CRW Short chain fatty acid transporter FYB61_RS19425 ENOG4107RZZ dna polymerase iii epsilon subunit FYB61_RS19430 ENOG4105BZS acriflavin resistance protein FYB61_RS19440 ENOG4108UMW Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) FYB61_RS19445 ENOG4105D1A Methyltransferase FYB61_RS19455 ENOG4105E9H Lytic Murein transglycosylase FYB61_RS19460 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH FYB61_RS19470 ENOG4108Q2J Inner membrane protein YebE FYB61_RS19480 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase FYB61_RS19505 ENOG4105CBG Sulfatase FYB61_RS19530 ENOG4105E8T Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity) FYB61_RS19535 ENOG4108WKG Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) FYB61_RS19550 ENOG4105KI2 Urea amidohydrolase subunit beta FYB61_RS19560 ENOG4108YZ9 Urea amidohydrolase subunit gamma FYB61_RS19565 ENOG4108M9X Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) FYB61_RS19580 ENOG4108ZIT Ferredoxin, 2FE-2S FYB61_RS19595 ENOG4108TZY GntR Family Transcriptional Regulator FYB61_RS19600 ENOG4105DV9 Methylaspartate ammonia-lyase FYB61_RS19620 ENOG4105ED1 spovr family FYB61_RS19625 ENOG4106AKX UPF0229 protein FYB61_RS19630 ENOG4105CYN Serine protein kinase FYB61_RS19635 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) FYB61_RS19650 ENOG4108Z11 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity) FYB61_RS19680 ENOG4108YX9 iron--sulfur cluster insertion protein erpA FYB61_RS19700 ENOG4108UM5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity) FYB61_RS19705 ENOG4105CH5 extracellular solute-binding protein, family 7 FYB61_RS19710 ENOG4105CMS peptidase U62, modulator of DNA gyrase FYB61_RS19735 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component FYB61_RS19740 ENOG4106XMA In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity) FYB61_RS19745 ENOG41090KQ Glyoxalase Bleomycin resistance protein (Dioxygenase FYB61_RS19750 ENOG4105C1J atp-dependent rna helicase FYB61_RS19760 ENOG4105DRR Transcriptional regulator, GntR family FYB61_RS19765 ENOG4105CD5 CoA-binding domain protein FYB61_RS19785 ENOG4108YXU transcriptional regulator AsnC family FYB61_RS19795 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) FYB61_RS19800 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) FYB61_RS19815 ENOG4108IQD Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity) FYB61_RS19820 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein FYB61_RS19840 ENOG4107T4Z adenosine kinase FYB61_RS19855 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase FYB61_RS19860 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein FYB61_RS19865 ENOG4108Z38 Catalyzes a trans-dehydration via an enolate intermediate (By similarity) FYB61_RS19870 ENOG4107QX9 Thiol disulfide interChange protein FYB61_RS19875 ENOG4105DFU Cell wall formation (By similarity) FYB61_RS19880 ENOG4105IPS esterase FYB61_RS19900 ENOG4108VKV Monofunctional biosynthetic peptidoglycan transglycosylase FYB61_RS19915 ENOG4108Z20 Acyl-transferase FYB61_RS19920 ENOG4105CD3 dihydroorotase FYB61_RS19935 ENOG4108UJU UPF0301 protein FYB61_RS19940 ENOG4105VCQ rubredoxin FYB61_RS19950 ENOG4107RZ7 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) FYB61_RS19980 ENOG4105C1G acyl-Coa dehydrogenase FYB61_RS19990 ENOG4105DTD Dehydrogenase FYB61_RS20005 ENOG4105C0Z ABC transporter FYB61_RS20010 ENOG4105CF8 branched-chain amino acid ABC transporter, permease FYB61_RS20015 ENOG4105C32 Amino acid ABC transporter (Permease) FYB61_RS20055 ENOG4105ENJ RND efflux system, outer membrane lipoprotein FYB61_RS20060 ENOG4105BZS acriflavin resistance protein FYB61_RS20075 ENOG4105DHA Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity) FYB61_RS20100 ENOG4108IAA Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity) FYB61_RS20105 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) FYB61_RS20135 ENOG4105CDA abc transporter atp-binding protein FYB61_RS20140 ENOG4105DRP amino acid AbC transporter FYB61_RS20145 ENOG4105EZ7 amino acid ABC transporter FYB61_RS20150 ENOG4107QXX ABC transporter FYB61_RS20155 ENOG4105CAK Cell division ATP-binding protein ftsE FYB61_RS20160 ENOG4105CRP Part of the ABC transporter FtsEX involved in FYB61_RS20175 ENOG4105CEN a g-specific adenine glycosylase FYB61_RS20190 ENOG4105C3R Methionine synthase FYB61_RS20195 ENOG4105CHI Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity) FYB61_RS20200 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) FYB61_RS20215 ENOG4105E26 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity) FYB61_RS20220 ENOG4105DFG type I secretion outer membrane protein FYB61_RS20225 ENOG4107Z67 Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity) FYB61_RS20235 ENOG4105CNK Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity) FYB61_RS20250 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) FYB61_RS20255 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FYB61_RS20260 ENOG4105BZU Histidine kinase FYB61_RS20270 ENOG4105GR3 Histidine kinase FYB61_RS20280 ENOG4108JQ1 Dehydrogenase FYB61_RS20285 ENOG4108M0I Transcriptional regulator FYB61_RS20295 ENOG4105P4J Allophanate hydrolase, subunit 1 FYB61_RS20340 ENOG4105DRR Transcriptional regulator, GntR family FYB61_RS20350 ENOG4105W39 Membrane FYB61_RS20355 ENOG4105C7B Threonine dehydratase FYB61_RS20360 ENOG4108Z9W Outer membrane porin FYB61_RS20370 ENOG4105EXG Transcriptional regulator FYB61_RS20380 ENOG4108JJ8 (ABC) transporter FYB61_RS20385 ENOG4108JJ9 ABC, transporter FYB61_RS20395 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii FYB61_RS20400 ENOG4105C4M (Ubiquinol oxidase) subunit I FYB61_RS20415 ENOG4105C2X Arabinose 5-phosphate isomerase FYB61_RS20435 ENOG4108IUZ ABC transporter FYB61_RS20440 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA FYB61_RS20445 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN FYB61_RS20455 ENOG4105CE2 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding FYB61_RS20465 ENOG4105C21 Displays ATPase and GTPase activities (By similarity) FYB61_RS20475 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) FYB61_RS20490 ENOG4105F55 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity) FYB61_RS20495 ENOG4105W4M Transport-associated protein FYB61_RS20505 ENOG4105D01 (LipO)protein FYB61_RS20525 ENOG4107QPK )-transporter FYB61_RS20530 ENOG4105DG4 malate L-lactate dehydrogenase FYB61_RS20535 ENOG4105CNI cell division protein FtsW FYB61_RS20540 ENOG4105CJN penicillin-binding protein FYB61_RS20550 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) FYB61_RS20580 ENOG4105CGK Exodeoxyribonuclease III FYB61_RS20590 ENOG4105EN6 Membrane FYB61_RS20600 ENOG4105EJC lysr family transcriptional regulator FYB61_RS20605 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) FYB61_RS20630 ENOG4107YNJ LysR family Transcriptional regulator FYB61_RS20635 ENOG4105K6H D-cysteine desulfhydrase FYB61_RS20640 ENOG4107RP9 extracellular solute-binding protein, family 3 FYB61_RS20645 ENOG4105EAD ABC transporter FYB61_RS20650 ENOG4105DRP amino acid AbC transporter FYB61_RS20655 ENOG4105CDA abc transporter atp-binding protein FYB61_RS20665 ENOG4108Z9W Outer membrane porin FYB61_RS20670 ENOG4105EYM Major Facilitator superfamily FYB61_RS20675 ENOG4105DWV Homoserine O-trans-acetylase FYB61_RS20685 ENOG4105DG4 malate L-lactate dehydrogenase FYB61_RS20730 ENOG4105DND Transcriptional regulator FYB61_RS20735 ENOG4105CCG Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity) FYB61_RS20740 ENOG4108Z9W Outer membrane porin FYB61_RS20750 ENOG4105C32 Amino acid ABC transporter (Permease) FYB61_RS20760 ENOG4105C0Z ABC transporter FYB61_RS20765 ENOG4108IV0 ABC, transporter FYB61_RS20775 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) FYB61_RS20785 ENOG41069M3 Transcriptional regulator FYB61_RS20795 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase FYB61_RS20805 ENOG4105E3B Multicopper oxidase FYB61_RS20850 ENOG4105E39 Enoyl-CoA hydratase FYB61_RS20855 ENOG41060WC Enoyl-CoA hydratase FYB61_RS20860 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) FYB61_RS20870 ENOG4105DEF Extracellular solute-binding protein, family 5 FYB61_RS20880 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component FYB61_RS20885 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FYB61_RS20890 ENOG4105C3U ABC transporter FYB61_RS20895 ENOG4108JQ7 (ABC) transporter FYB61_RS20905 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) FYB61_RS20910 ENOG4105C4R Atp-dependent dna helicase FYB61_RS20915 ENOG4105C25 Primosomal protein n' FYB61_RS20930 ENOG4105KNM Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity) FYB61_RS20950 ENOG4107S15 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) FYB61_RS20960 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) FYB61_RS20965 ENOG4107RAZ it plays a direct role in the translocation of protons across the membrane (By similarity) FYB61_RS20980 ENOG4105E39 Enoyl-CoA hydratase FYB61_RS21015 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family FYB61_RS21020 ENOG4105CA3 membrane-bound lytic murein transglycosylase FYB61_RS21025 ENOG4105NWN ApaG protein FYB61_RS21035 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) FYB61_RS21045 ENOG4105DDQ anthranilate synthase FYB61_RS21065 ENOG4105CYX Short-chain dehydrogenase reductase Sdr FYB61_RS21085 ENOG4105C8F Beta-lactamase domain protein FYB61_RS21095 ENOG4108S4H thioesterase Superfamily protein FYB61_RS21150 ENOG4105DRR Transcriptional regulator, GntR family FYB61_RS21155 ENOG4105CIF Ornithine Cyclodeaminase FYB61_RS21180 ENOG4108SF5 RNA Polymerase FYB61_RS21195 ENOG4106QJH hemin transport protein FYB61_RS21200 ENOG4107R4I Periplasmic binding protein FYB61_RS21205 ENOG4105EHG Permease protein FYB61_RS21215 ENOG4105EWC Purine nucleoside phosphorylase FYB61_RS21225 ENOG4105CF1 Alkylated DNA repair protein FYB61_RS21230 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) FYB61_RS21235 ENOG4105BZU Histidine kinase FYB61_RS21245 ENOG4108NST exported protein FYB61_RS21250 ENOG4105DDW LysR family Transcriptional regulator FYB61_RS21260 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) FYB61_RS21270 ENOG4105C5R Aminotransferase FYB61_RS21275 ENOG4105DRR Transcriptional regulator, GntR family FYB61_RS21285 ENOG4105BZ9 Cytochrome C oxidase, subunit I FYB61_RS21305 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F FYB61_RS21330 ENOG4105DDW LysR family Transcriptional regulator FYB61_RS21345 ENOG4105CHU acetyl-coa acetyltransferase FYB61_RS21365 ENOG4105CD5 CoA-binding domain protein FYB61_RS21400 ENOG4105C6Y Udp-glucose 6-dehydrogenase FYB61_RS21405 ENOG4105C0R drug resistance transporter emrb qaca subfamily FYB61_RS21460 ENOG4107QS1 Cytochrome C Oxidase, Subunit III FYB61_RS21470 ENOG4105BZ9 Cytochrome C oxidase, subunit I FYB61_RS21475 ENOG4105CV4 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity) FYB61_RS21490 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) FYB61_RS21500 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FYB61_RS21510 ENOG4105C4W S-formylglutathione hydrolase FYB61_RS21515 ENOG4107QPD alcohol dehydrogenase FYB61_RS21535 ENOG4105EIF outer membrane protein W FYB61_RS21545 ENOG4105DHJ ABC, transporter FYB61_RS21550 ENOG4105CY3 ABC transporter, permease FYB61_RS21555 ENOG4107PE3 Mammalian cell entry related domain protein FYB61_RS21570 ENOG4105DA5 (ABC) transporter FYB61_RS21575 ENOG4105E3A (ABC) transporter FYB61_RS21595 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) FYB61_RS21605 ENOG4105ECC imidazole-glycerol-phosphate dehydratase FYB61_RS21615 ENOG4105CJV Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase FYB61_RS21630 ENOG4105KPZ phosphoribosyl-atp pyrophosphatase FYB61_RS21635 ENOG4107YU2 histidine triad (hIT) protein FYB61_RS21640 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) FYB61_RS21665 ENOG4107QNR UPF0135 protein FYB61_RS21675 ENOG4108R5F Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) FYB61_RS21680 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) FYB61_RS21685 ENOG4105EIX cytochrome c1 FYB61_RS21690 ENOG4107MKT Stringent starvation protein a FYB61_RS21695 ENOG4105KB2 stringent starvation protein b FYB61_RS21715 ENOG4105ENX hydrolase FYB61_RS21725 ENOG4106NZI LysR family Transcriptional regulator FYB61_RS21730 ENOG4105C3M thioredoxin reductase FYB61_RS21750 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F FYB61_RS21810 ENOG4106D0Q Type IV secretion system protein VirB2 FYB61_RS21815 ENOG4106E4H Type IV secretory pathway VirB3 family protein FYB61_RS21835 ENOG4105PDG Type IV secretion system protein VirB8 FYB61_RS21850 ENOG4108EHY type IV secretion system FYB61_RS21860 ENOG410631K Membrane FYB61_RS21880 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) FYB61_RS21885 ENOG4105DEF Extracellular solute-binding protein, family 5 FYB61_RS21890 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component FYB61_RS21895 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FYB61_RS21905 ENOG4105HA9 of methanol dehydrogenase type FYB61_RS21915 ENOG4105C1J atp-dependent rna helicase FYB61_RS21920 ENOG410829K Lysine exporter protein (Lyse ygga) FYB61_RS21935 ENOG4108UQY Iron-storage protein FYB61_RS21955 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FYB61_RS21965 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) FYB61_RS21970 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) FYB61_RS21975 ENOG4105ETE Transcriptional regulator (LacI family FYB61_RS21990 ENOG4105E0C molybdate abc transporter FYB61_RS21995 ENOG4108IJ6 ABC transporter FYB61_RS22000 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) FYB61_RS22005 ENOG4108IJ9 (ABC) transporter FYB61_RS22010 ENOG4105BZ7 extracellular solute-binding protein family 1 FYB61_RS22015 ENOG4105E4X binding-protein-dependent transport systems inner membrane Component FYB61_RS22020 ENOG4105DRS transport system, permease FYB61_RS22055 ENOG410829K Lysine exporter protein (Lyse ygga) FYB61_RS22070 ENOG4105C1G acyl-Coa dehydrogenase FYB61_RS22080 ENOG4105CHU acetyl-coa acetyltransferase FYB61_RS22085 ENOG4107QX3 carboxylase FYB61_RS22115 ENOG4105H1G trap transporter solute receptor taxi family FYB61_RS22130 ENOG4108RPN Protein smg homolog FYB61_RS22145 ENOG4105C9U ATP-dependent DNA helicase RecQ FYB61_RS22160 ENOG4105Y36 Binding-protein-dependent transport systems, inner membrane component FYB61_RS22165 ENOG4105CHR reductase FYB61_RS22170 ENOG4105C26 Dehydrogenase FYB61_RS22180 ENOG4105C7K acetolactate synthase FYB61_RS22185 ENOG4108YXU transcriptional regulator AsnC family FYB61_RS22190 ENOG4105FFC UPF0187 protein FYB61_RS22220 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) FYB61_RS22230 ENOG4105K5X acetyltransferase FYB61_RS22245 ENOG4105DMF Dehydrogenase FYB61_RS22265 ENOG4108FUF Transcriptional regulator, IclR family FYB61_RS22270 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FYB61_RS22275 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) FYB61_RS22280 ENOG4105CI4 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity) FYB61_RS22285 ENOG4105VG0 50S ribosomal protein l34 FYB61_RS22290 ENOG4105X5M RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity) FYB61_RS22295 ENOG4105VAS Could be involved in insertion of integral membrane proteins into the membrane (By similarity) FYB61_RS22305 ENOG4105CH6 catalase FYB61_RS22310 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component FYB61_RS22330 ENOG4105CH2 amidohydrolase FYB61_RS22335 ENOG4108JQ7 (ABC) transporter FYB61_RS22340 ENOG4105C3U ABC transporter FYB61_RS22355 ENOG4105DEF Extracellular solute-binding protein, family 5 FYB61_RS22375 ENOG41062D9 Histidine kinase FYB61_RS22395 ENOG4105CHM Aminotransferase FYB61_RS22400 ENOG4105VEQ Cold shock protein