locus-tag	class	description
FYB61_RS00010	COG0357	Ribosomal RNA small subunit methyltransferase G
FYB61_RS00015	COG1192	Involved in chromosome partitioning
FYB61_RS00025	COG1475	DNA binding
FYB61_RS00030	COG0252	asparaginase activity
FYB61_RS00050	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FYB61_RS00060	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FYB61_RS00075	COG0081	regulation of translation
FYB61_RS00080	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FYB61_RS00085	COG0222	ribosome binding
FYB61_RS00095	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FYB61_RS00130	COG1230	cation diffusion facilitator family transporter
FYB61_RS00140	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FYB61_RS00145	COG0049	tRNA binding
FYB61_RS00155	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FYB61_RS00165	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FYB61_RS00175	COG0089	rRNA binding
FYB61_RS00180	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FYB61_RS00190	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FYB61_RS00195	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FYB61_RS00200	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FYB61_RS00205	COG0255	Belongs to the universal ribosomal protein uL29 family
FYB61_RS00210	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FYB61_RS00230	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FYB61_RS00235	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FYB61_RS00240	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FYB61_RS00245	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FYB61_RS00250	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FYB61_RS00260	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FYB61_RS00265	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FYB61_RS00270	COG1841	ribosomal large subunit assembly
FYB61_RS00280	COG0201	protein transport
FYB61_RS00285	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FYB61_RS00290	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FYB61_RS00295	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FYB61_RS00300	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FYB61_RS00305	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FYB61_RS00310	COG0202	RNA polymerase activity
FYB61_RS00315	COG0203	ribosomal protein L17
FYB61_RS00320	COG0537	adenosine 5'-monophosphoramidase activity
FYB61_RS00325	COG1324	tolerance protein
FYB61_RS00330	COG4232	protein-disulfide reductase activity
FYB61_RS00345	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FYB61_RS00355	COG1333	cytochrome c biogenesis protein
FYB61_RS00360	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FYB61_RS00380	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FYB61_RS00385	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FYB61_RS00405	COG2814	Major facilitator Superfamily
FYB61_RS00450	COG0402	S-adenosylhomocysteine deaminase activity
FYB61_RS00460	COG0438	transferase activity, transferring glycosyl groups
FYB61_RS00480	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FYB61_RS00510	COG2186	Transcriptional regulator
FYB61_RS00530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FYB61_RS00535	COG1956	GAF domain-containing protein
FYB61_RS00540	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FYB61_RS00570	COG0531	amino acid
FYB61_RS00600	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FYB61_RS00605	COG3568	Endonuclease Exonuclease Phosphatase
FYB61_RS00610	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FYB61_RS00630	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FYB61_RS00640	COG0367	asparagine synthase
FYB61_RS00660	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FYB61_RS00665	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FYB61_RS00705	COG0367	asparagine synthase
FYB61_RS00710	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
FYB61_RS00735	COG0367	asparagine synthase
FYB61_RS00745	COG0438	transferase activity, transferring glycosyl groups
FYB61_RS00765	COG0438	transferase activity, transferring glycosyl groups
FYB61_RS00770	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FYB61_RS00775	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FYB61_RS00805	COG0859	PFAM glycosyl transferase family 9
FYB61_RS00830	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FYB61_RS00835	COG1127	ABC transporter
FYB61_RS00855	COG1686	Belongs to the peptidase S11 family
FYB61_RS00895	COG2096	Adenosyltransferase
FYB61_RS00920	COG0523	cobalamin synthesis protein
FYB61_RS00925	COG0735	belongs to the Fur family
FYB61_RS00935	COG1121	(ABC) transporter
FYB61_RS00945	COG0803	Belongs to the bacterial solute-binding protein 9 family
FYB61_RS00955	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FYB61_RS00965	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FYB61_RS00975	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FYB61_RS00980	COG1560	Kdo2-lipid A biosynthetic process
FYB61_RS00990	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FYB61_RS01010	COG1950	PFAM Membrane protein of
FYB61_RS01020	COG0583	DNA-binding transcription factor activity
FYB61_RS01030	COG0477	Major facilitator Superfamily
FYB61_RS01055	COG0513	Belongs to the DEAD box helicase family
FYB61_RS01065	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FYB61_RS01070	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FYB61_RS01085	COG0735	belongs to the Fur family
FYB61_RS01105	COG0438	transferase activity, transferring glycosyl groups
FYB61_RS01130	COG0640	Transcriptional regulator
FYB61_RS01190	COG0583	DNA-binding transcription factor activity
FYB61_RS01205	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FYB61_RS01210	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FYB61_RS01215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYB61_RS01230	COG0758	DNA mediated transformation
FYB61_RS01235	COG1522	sequence-specific DNA binding
FYB61_RS01245	COG0242	peptide deformylase activity
FYB61_RS01260	COG0546	phosphoglycolate phosphatase activity
FYB61_RS01280	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FYB61_RS01285	COG1942	4-Oxalocrotonate Tautomerase
FYB61_RS01290	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FYB61_RS01325	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FYB61_RS01325	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FYB61_RS01335	COG5000	phosphorelay sensor kinase activity
FYB61_RS01340	COG2204	response regulator
FYB61_RS01365	COG2068	MobA-Related Protein
FYB61_RS01380	COG0596	Alpha beta hydrolase
FYB61_RS01385	COG2309	aminopeptidase activity
FYB61_RS01390	COG1335	isochorismatase
FYB61_RS01415	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FYB61_RS01440	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FYB61_RS01445	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FYB61_RS01465	COG2226	methyltransferase
FYB61_RS01480	COG3181	Tripartite tricarboxylate transporter family receptor
FYB61_RS01490	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FYB61_RS01495	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FYB61_RS01510	COG4942	peptidase
FYB61_RS01515	COG0793	Belongs to the peptidase S41A family
FYB61_RS01520	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FYB61_RS01540	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FYB61_RS01575	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FYB61_RS01580	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FYB61_RS01585	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FYB61_RS01595	COG0142	geranyltranstransferase activity
FYB61_RS01605	COG0583	DNA-binding transcription factor activity
FYB61_RS01615	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
FYB61_RS01620	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FYB61_RS01635	COG2994	toxin metabolic process
FYB61_RS01645	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
FYB61_RS01650	COG2274	protein secretion by the type I secretion system
FYB61_RS01655	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYB61_RS01660	COG1538	Outer membrane efflux protein
FYB61_RS01675	COG0765	amino acid transport
FYB61_RS01680	COG0765	amino acid transport
FYB61_RS01685	COG1126	abc transporter atp-binding protein
FYB61_RS01705	COG1028	Short-chain dehydrogenase reductase Sdr
FYB61_RS01715	COG1802	Transcriptional regulator
FYB61_RS01730	COG1802	Transcriptional regulator
FYB61_RS01740	COG0318	PFAM AMP-dependent synthetase and ligase
FYB61_RS01750	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FYB61_RS01780	COG0583	DNA-binding transcription factor activity
FYB61_RS01785	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYB61_RS01790	COG2301	Belongs to the HpcH HpaI aldolase family
FYB61_RS01795	COG2188	Transcriptional regulator
FYB61_RS01840	COG0583	DNA-binding transcription factor activity
FYB61_RS01845	COG1024	Enoyl-CoA hydratase
FYB61_RS01880	COG1028	Short-chain dehydrogenase reductase Sdr
FYB61_RS01895	COG1902	pentaerythritol trinitrate reductase activity
FYB61_RS01920	COG0745	RESPONSE REGULATOR receiver
FYB61_RS01960	COG2890	protein-(glutamine-N5) methyltransferase activity
FYB61_RS01965	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FYB61_RS01975	COG3181	Tripartite tricarboxylate transporter family receptor
FYB61_RS02045	COG4211	Belongs to the binding-protein-dependent transport system permease family
FYB61_RS02055	COG0683	leucine binding
FYB61_RS02060	COG0154	amidase activity
FYB61_RS02065	COG0288	reversible hydration of carbon dioxide
FYB61_RS02085	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FYB61_RS02100	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FYB61_RS02110	COG1414	Transcriptional regulator
FYB61_RS02115	COG1028	Short-chain dehydrogenase reductase Sdr
FYB61_RS02120	COG2031	fatty acid transporter
FYB61_RS02125	COG1250	3-hydroxyacyl-CoA dehydrogenase
FYB61_RS02155	COG2808	Putative FMN-binding domain
FYB61_RS02160	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FYB61_RS02165	COG0747	negative chemotaxis
FYB61_RS02170	COG0657	acetylesterase activity
FYB61_RS02180	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FYB61_RS02185	COG2207	Transcriptional regulator
FYB61_RS02210	COG1538	Outer membrane efflux protein
FYB61_RS02225	COG0583	DNA-binding transcription factor activity
FYB61_RS02230	COG0628	permease
FYB61_RS02240	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FYB61_RS02245	COG0251	oxidation-reduction process
FYB61_RS02255	COG0330	HflC and HflK could
FYB61_RS02260	COG3422	double-strand break repair
FYB61_RS02275	COG0583	DNA-binding transcription factor activity
FYB61_RS02305	COG3181	Tripartite tricarboxylate transporter family receptor
FYB61_RS02310	COG0318	PFAM AMP-dependent synthetase and ligase
FYB61_RS02315	COG1414	Transcriptional regulator
FYB61_RS02320	COG1024	Enoyl-CoA hydratase
FYB61_RS02325	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FYB61_RS02330	COG3181	Tripartite tricarboxylate transporter family receptor
FYB61_RS02335	COG0604	alcohol dehydrogenase
FYB61_RS02340	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYB61_RS02345	COG0583	DNA-binding transcription factor activity
FYB61_RS02355	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYB61_RS02370	COG0251	oxidation-reduction process
FYB61_RS02380	COG2031	fatty acid transporter
FYB61_RS02410	COG1278	Cold shock
FYB61_RS02415	COG0583	DNA-binding transcription factor activity
FYB61_RS02435	COG1228	amidohydrolase
FYB61_RS02440	COG0523	cobalamin synthesis protein
FYB61_RS02445	COG1819	glycosyl
FYB61_RS02525	COG0625	glutathione transferase activity
FYB61_RS02540	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FYB61_RS02545	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FYB61_RS02550	COG1652	LysM domain
FYB61_RS02575	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYB61_RS02580	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FYB61_RS02615	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FYB61_RS02670	COG0583	DNA-binding transcription factor activity
FYB61_RS02675	COG3181	Tripartite tricarboxylate transporter family receptor
FYB61_RS02685	COG1024	Enoyl-CoA hydratase
FYB61_RS02690	COG3181	Tripartite tricarboxylate transporter family receptor
FYB61_RS02715	COG0028	Belongs to the TPP enzyme family
FYB61_RS02725	COG1024	Enoyl-CoA hydratase
FYB61_RS02725	COG1250	3-hydroxyacyl-CoA dehydrogenase
FYB61_RS02730	COG3181	Tripartite tricarboxylate transporter family receptor
FYB61_RS02735	COG1414	Transcriptional regulator
FYB61_RS02755	COG0318	PFAM AMP-dependent synthetase and ligase
FYB61_RS02760	COG1609	Transcriptional regulator
FYB61_RS02785	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FYB61_RS02790	COG1024	Enoyl-CoA hydratase
FYB61_RS02805	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYB61_RS02810	COG3181	Tripartite tricarboxylate transporter family receptor
FYB61_RS02815	COG0583	DNA-binding transcription factor activity
FYB61_RS02830	COG1960	acyl-CoA dehydrogenase activity
FYB61_RS02845	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FYB61_RS02855	COG1053	succinate dehydrogenase
FYB61_RS02855	COG3976	FMN-binding domain protein
FYB61_RS02890	COG0683	leucine binding
FYB61_RS02900	COG1309	transcriptional regulator
FYB61_RS02920	COG1028	Short-chain dehydrogenase reductase Sdr
FYB61_RS02925	COG1960	acyl-CoA dehydrogenase activity
FYB61_RS02930	COG1028	Short-chain dehydrogenase reductase Sdr
FYB61_RS02935	COG0318	PFAM AMP-dependent synthetase and ligase
FYB61_RS02945	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FYB61_RS02955	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
FYB61_RS02970	COG2030	dehydratase
FYB61_RS02980	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYB61_RS02985	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYB61_RS02990	COG3181	Tripartite tricarboxylate transporter family receptor
FYB61_RS03015	COG0559	Belongs to the binding-protein-dependent transport system permease family
FYB61_RS03035	COG1902	pentaerythritol trinitrate reductase activity
FYB61_RS03035	COG0446	pyridine nucleotide-disulphide oxidoreductase
FYB61_RS03050	COG0427	acetyl-CoA hydrolase
FYB61_RS03055	COG0318	PFAM AMP-dependent synthetase and ligase
FYB61_RS03070	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FYB61_RS03090	COG0183	Belongs to the thiolase family
FYB61_RS03095	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FYB61_RS03105	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYB61_RS03110	COG0583	DNA-binding transcription factor activity
FYB61_RS03115	COG1960	acyl-CoA dehydrogenase activity
FYB61_RS03130	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
FYB61_RS03155	COG1309	transcriptional regulator
FYB61_RS03165	COG1024	Enoyl-CoA hydratase
FYB61_RS03185	COG1024	Enoyl-CoA hydratase
FYB61_RS03190	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYB61_RS03195	COG3181	Tripartite tricarboxylate transporter family receptor
FYB61_RS03200	COG1454	alcohol dehydrogenase
FYB61_RS03205	COG1024	Enoyl-CoA hydratase
FYB61_RS03225	COG1012	belongs to the aldehyde dehydrogenase family
FYB61_RS03230	COG0431	NADPH-dependent FMN reductase
FYB61_RS03235	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FYB61_RS03240	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FYB61_RS03255	COG1414	Transcriptional regulator
FYB61_RS03260	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FYB61_RS03265	COG1028	Short-chain dehydrogenase reductase Sdr
FYB61_RS03270	COG3181	Tripartite tricarboxylate transporter family receptor
FYB61_RS03295	COG0318	PFAM AMP-dependent synthetase and ligase
FYB61_RS03315	COG1024	Enoyl-CoA hydratase
FYB61_RS03325	COG1960	acyl-CoA dehydrogenase activity
FYB61_RS03330	COG1024	Enoyl-CoA hydratase
FYB61_RS03335	COG0183	Belongs to the thiolase family
FYB61_RS03340	COG3181	Tripartite tricarboxylate transporter family receptor
FYB61_RS03355	COG0583	DNA-binding transcription factor activity
FYB61_RS03360	COG2267	carboxylic ester hydrolase activity
FYB61_RS03375	COG0625	glutathione transferase activity
FYB61_RS03380	COG3181	Tripartite tricarboxylate transporter family receptor
FYB61_RS03390	COG2186	Transcriptional regulator
FYB61_RS03395	COG1012	belongs to the aldehyde dehydrogenase family
FYB61_RS03400	COG0626	cystathionine gamma-synthase activity
FYB61_RS03440	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FYB61_RS03445	COG0436	Aminotransferase
FYB61_RS03465	COG1473	amidohydrolase
FYB61_RS03470	COG1414	Transcriptional regulator
FYB61_RS03480	COG0154	amidase activity
FYB61_RS03540	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FYB61_RS03555	COG3135	benzoate transporter
FYB61_RS03580	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FYB61_RS03600	COG5444	nuclease activity
FYB61_RS03720	COG3468	outer membrane autotransporter barrel domain protein
FYB61_RS03780	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FYB61_RS03825	COG0489	protein tyrosine kinase activity
FYB61_RS03865	COG1982	Orn Lys Arg decarboxylase major
FYB61_RS03870	COG2081	HI0933 family
FYB61_RS03875	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FYB61_RS03890	COG0509	glycine decarboxylation via glycine cleavage system
FYB61_RS03915	COG1024	Enoyl-CoA hydratase
FYB61_RS03935	COG4172	Belongs to the ABC transporter superfamily
FYB61_RS03940	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FYB61_RS03945	COG0601	transmembrane transport
FYB61_RS03950	COG0747	negative chemotaxis
FYB61_RS03990	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FYB61_RS03995	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FYB61_RS04010	COG0438	transferase activity, transferring glycosyl groups
FYB61_RS04025	COG0438	transferase activity, transferring glycosyl groups
FYB61_RS04030	COG0438	transferase activity, transferring glycosyl groups
FYB61_RS04035	COG0166	Belongs to the GPI family
FYB61_RS04050	COG0277	FAD linked oxidase domain protein
FYB61_RS04055	COG0745	RESPONSE REGULATOR receiver
FYB61_RS04060	COG0642	Histidine kinase
FYB61_RS04065	COG1368	sulfuric ester hydrolase activity
FYB61_RS04150	COG0012	GTP binding
FYB61_RS04165	COG0745	RESPONSE REGULATOR receiver
FYB61_RS04170	COG3181	Tripartite tricarboxylate transporter family receptor
FYB61_RS04175	COG1309	transcriptional regulator
FYB61_RS04185	COG2814	Major facilitator Superfamily
FYB61_RS04210	COG0281	malic enzyme
FYB61_RS04210	COG0280	phosphate acetyltransferase
FYB61_RS04220	COG0601	transmembrane transport
FYB61_RS04225	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FYB61_RS04230	COG4172	Belongs to the ABC transporter superfamily
FYB61_RS04245	COG0583	DNA-binding transcription factor activity
FYB61_RS04260	COG0640	Transcriptional regulator
FYB61_RS04275	COG3135	benzoate transporter
FYB61_RS04280	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FYB61_RS04285	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FYB61_RS04290	COG0742	ribosomal rna small subunit methyltransferase
FYB61_RS04305	COG3639	organic phosphonate transmembrane transporter activity
FYB61_RS04310	COG3639	organic phosphonate transmembrane transporter activity
FYB61_RS04340	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FYB61_RS04345	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FYB61_RS04355	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FYB61_RS04360	COG1058	Belongs to the CinA family
FYB61_RS04360	COG1546	Belongs to the CinA family
FYB61_RS04365	COG0284	orotidine-5'-phosphate decarboxylase activity
FYB61_RS04370	COG1252	NADH dehydrogenase
FYB61_RS04395	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FYB61_RS04415	COG1053	succinate dehydrogenase
FYB61_RS04425	COG0583	DNA-binding transcription factor activity
FYB61_RS04435	COG3181	Tripartite tricarboxylate transporter family receptor
FYB61_RS04440	COG1414	Transcriptional regulator
FYB61_RS04455	COG1335	isochorismatase
FYB61_RS04470	COG0405	Gamma-glutamyltransferase
FYB61_RS04485	COG1960	acyl-CoA dehydrogenase activity
FYB61_RS04490	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYB61_RS04495	COG3181	Tripartite tricarboxylate transporter family receptor
FYB61_RS04500	COG0583	DNA-binding transcription factor activity
FYB61_RS04525	COG3181	Tripartite tricarboxylate transporter family receptor
FYB61_RS04530	COG0583	DNA-binding transcription factor activity
FYB61_RS04535	COG5001	Diguanylate cyclase
FYB61_RS04590	COG1250	3-hydroxyacyl-CoA dehydrogenase
FYB61_RS04590	COG1024	Enoyl-CoA hydratase
FYB61_RS04595	COG0318	PFAM AMP-dependent synthetase and ligase
FYB61_RS04610	COG1024	Enoyl-CoA hydratase
FYB61_RS04615	COG1024	Enoyl-CoA hydratase
FYB61_RS04620	COG0318	PFAM AMP-dependent synthetase and ligase
FYB61_RS04625	COG1960	acyl-CoA dehydrogenase activity
FYB61_RS04665	COG3685	Protein conserved in bacteria
FYB61_RS04675	COG0387	Pfam Sodium calcium exchanger
FYB61_RS04680	COG3795	YCII-related domain
FYB61_RS04685	COG2188	Transcriptional regulator
FYB61_RS04710	COG0154	amidase activity
FYB61_RS04715	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYB61_RS04720	COG1024	Enoyl-CoA hydratase
FYB61_RS04730	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FYB61_RS04745	COG1028	Short-chain dehydrogenase reductase Sdr
FYB61_RS04750	COG1414	Transcriptional regulator
FYB61_RS04765	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FYB61_RS04770	COG0251	oxidation-reduction process
FYB61_RS04775	COG0559	Belongs to the binding-protein-dependent transport system permease family
FYB61_RS04795	COG1902	pentaerythritol trinitrate reductase activity
FYB61_RS04800	COG0583	DNA-binding transcription factor activity
FYB61_RS04810	COG0590	tRNA wobble adenosine to inosine editing
FYB61_RS04815	COG2807	transmembrane transport
FYB61_RS04820	COG0307	riboflavin synthase, alpha
FYB61_RS04825	COG3181	Tripartite tricarboxylate transporter family receptor
FYB61_RS04830	COG1522	sequence-specific DNA binding
FYB61_RS04840	COG0318	PFAM AMP-dependent synthetase and ligase
FYB61_RS04850	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FYB61_RS04890	COG1418	mRNA catabolic process
FYB61_RS04900	COG1335	isochorismatase
FYB61_RS04925	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYB61_RS04930	COG2274	protein secretion by the type I secretion system
FYB61_RS04940	COG1538	Outer membrane efflux protein
FYB61_RS04955	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FYB61_RS04965	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYB61_RS04975	COG1309	transcriptional regulator
FYB61_RS04980	COG1960	acyl-CoA dehydrogenase activity
FYB61_RS04985	COG1028	Short-chain dehydrogenase reductase Sdr
FYB61_RS04990	COG2076	Multidrug Resistance protein
FYB61_RS04995	COG1309	transcriptional regulator
FYB61_RS05015	COG0840	transmembrane signaling receptor activity
FYB61_RS05030	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FYB61_RS05055	COG1012	belongs to the aldehyde dehydrogenase family
FYB61_RS05065	COG1024	Enoyl-CoA hydratase
FYB61_RS05075	COG2199	diguanylate cyclase activity
FYB61_RS05075	COG2203	Gaf domain
FYB61_RS05095	COG0154	amidase activity
FYB61_RS05125	COG3945	hemerythrin HHE cation binding domain
FYB61_RS05140	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FYB61_RS05140	COG2169	Transcriptional regulator
FYB61_RS05160	COG1271	oxidase subunit
FYB61_RS05165	COG1294	oxidase, subunit
FYB61_RS05175	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FYB61_RS05205	COG0596	Alpha beta hydrolase
FYB61_RS05210	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FYB61_RS05245	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FYB61_RS05250	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FYB61_RS05260	COG2070	2-Nitropropane dioxygenase
FYB61_RS05275	COG2207	Transcriptional regulator
FYB61_RS05275	COG1917	Cupin 2, conserved barrel domain protein
FYB61_RS05295	COG2900	Belongs to the SlyX family
FYB61_RS05305	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FYB61_RS05335	COG0583	DNA-binding transcription factor activity
FYB61_RS05350	COG0583	DNA-binding transcription factor activity
FYB61_RS05375	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
FYB61_RS05385	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FYB61_RS05390	COG1845	cytochrome c oxidase, subunit III
FYB61_RS05395	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FYB61_RS05400	COG0640	Transcriptional regulator
FYB61_RS05465	COG1666	GTP binding
FYB61_RS05490	COG1028	Short-chain dehydrogenase reductase Sdr
FYB61_RS05500	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FYB61_RS05505	COG1845	cytochrome c oxidase, subunit III
FYB61_RS05510	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FYB61_RS05515	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FYB61_RS05520	COG0477	Major facilitator Superfamily
FYB61_RS05535	COG5006	permease, DMT superfamily
FYB61_RS05555	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FYB61_RS05570	COG3383	formate dehydrogenase (NAD+) activity
FYB61_RS05590	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FYB61_RS05595	COG0303	'Molybdopterin
FYB61_RS05600	COG0521	Mo-molybdopterin cofactor biosynthetic process
FYB61_RS05610	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FYB61_RS05625	COG0412	Dienelactone hydrolase
FYB61_RS05635	COG0678	peroxiredoxin activity
FYB61_RS05645	COG0697	spore germination
FYB61_RS05690	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FYB61_RS05695	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FYB61_RS05700	COG1335	isochorismatase
FYB61_RS05705	COG0523	cobalamin synthesis protein
FYB61_RS05710	COG3181	Tripartite tricarboxylate transporter family receptor
FYB61_RS05725	COG3181	Tripartite tricarboxylate transporter family receptor
FYB61_RS05735	COG1802	Transcriptional regulator
FYB61_RS05755	COG0667	Aldo Keto reductase
FYB61_RS05765	COG4535	Mg2 and Co2 transporter CorC
FYB61_RS05775	COG1702	phosphate starvation-inducible protein PhoH
FYB61_RS05790	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FYB61_RS05795	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FYB61_RS05800	COG1862	Preprotein translocase
FYB61_RS05805	COG0343	queuine tRNA-ribosyltransferase activity
FYB61_RS05815	COG2027	D-alanyl-D-alanine carboxypeptidase
FYB61_RS05860	COG0741	lytic transglycosylase activity
FYB61_RS05865	COG0436	Aminotransferase
FYB61_RS05875	COG0281	malic enzyme
FYB61_RS05875	COG0280	phosphate acetyltransferase
FYB61_RS05885	COG2732	(Barnase) inhibitor
FYB61_RS05890	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FYB61_RS05895	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FYB61_RS05900	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FYB61_RS05910	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FYB61_RS05915	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FYB61_RS05930	COG0625	glutathione transferase activity
FYB61_RS05960	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FYB61_RS05970	COG0306	phosphate transporter
FYB61_RS05975	COG0521	Mo-molybdopterin cofactor biosynthetic process
FYB61_RS05985	COG0739	heme binding
FYB61_RS05995	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FYB61_RS06045	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FYB61_RS06065	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FYB61_RS06070	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FYB61_RS06075	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FYB61_RS06080	COG0009	L-threonylcarbamoyladenylate synthase
FYB61_RS06085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYB61_RS06090	COG1414	Transcriptional regulator
FYB61_RS06105	COG0765	amino acid transport
FYB61_RS06110	COG1126	abc transporter atp-binding protein
FYB61_RS06130	COG0028	Belongs to the TPP enzyme family
FYB61_RS06135	COG0583	DNA-binding transcription factor activity
FYB61_RS06140	COG4974	Belongs to the 'phage' integrase family
FYB61_RS06145	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FYB61_RS06150	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
FYB61_RS06160	COG1686	Belongs to the peptidase S11 family
FYB61_RS06170	COG2814	Major facilitator Superfamily
FYB61_RS06185	COG1074	ATP-dependent DNA helicase activity
FYB61_RS06195	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FYB61_RS06210	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYB61_RS06215	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FYB61_RS06225	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FYB61_RS06235	COG0505	Belongs to the CarA family
FYB61_RS06240	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FYB61_RS06270	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FYB61_RS06300	COG1053	succinate dehydrogenase
FYB61_RS06300	COG3976	FMN-binding domain protein
FYB61_RS06305	COG3181	Tripartite tricarboxylate transporter family receptor
FYB61_RS06335	COG3842	ATPase activity
FYB61_RS06345	COG0395	ABC-type sugar transport system, permease component
FYB61_RS06380	COG0420	3'-5' exonuclease activity
FYB61_RS06395	COG2111	Na H antiporter
FYB61_RS06395	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FYB61_RS06400	COG1006	Multisubunit Na H antiporter MnhC subunit
FYB61_RS06405	COG0651	ATP synthesis coupled electron transport
FYB61_RS06410	COG1863	multisubunit Na H antiporter MnhE subunit
FYB61_RS06415	COG2212	antiporter activity
FYB61_RS06435	COG0590	tRNA wobble adenosine to inosine editing
FYB61_RS06440	COG1619	proteins homologs of microcin C7 resistance protein MccF
FYB61_RS06445	COG1024	Enoyl-CoA hydratase
FYB61_RS06450	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FYB61_RS06460	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FYB61_RS06465	COG0488	(ABC) transporter
FYB61_RS06495	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FYB61_RS06500	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FYB61_RS06505	COG2252	PERMEase
FYB61_RS06515	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FYB61_RS06555	COG0789	Transcriptional regulator
FYB61_RS06565	COG0678	peroxiredoxin activity
FYB61_RS06565	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FYB61_RS06575	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FYB61_RS06580	COG0584	glycerophosphoryl diester phosphodiesterase
FYB61_RS06585	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FYB61_RS06595	COG4181	ATPase activity
FYB61_RS06635	COG4336	lyase activity
FYB61_RS06650	COG2197	response regulator
FYB61_RS06660	COG3064	Membrane
FYB61_RS06660	COG3210	domain, Protein
FYB61_RS06660	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
FYB61_RS06670	COG3121	Chaperone
FYB61_RS06675	COG3188	usher protein
FYB61_RS06680	COG3539	Fimbrial protein
FYB61_RS06685	COG2831	hemolysin activation secretion protein
FYB61_RS06700	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FYB61_RS06725	COG0583	DNA-binding transcription factor activity
FYB61_RS06745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYB61_RS06750	COG0765	amino acid transport
FYB61_RS06755	COG1126	abc transporter atp-binding protein
FYB61_RS06760	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FYB61_RS06765	COG1758	RNA polymerase activity
FYB61_RS06770	COG0194	GDP metabolic process
FYB61_RS06775	COG3258	Cytochrome c
FYB61_RS06780	COG2863	cytochrome
FYB61_RS06785	COG1028	Short-chain dehydrogenase reductase Sdr
FYB61_RS06790	COG0791	NLP P60 protein
FYB61_RS06795	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FYB61_RS06835	COG5002	protein histidine kinase activity
FYB61_RS06835	COG5001	Diguanylate cyclase
FYB61_RS06845	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FYB61_RS06850	COG0174	glutamine synthetase
FYB61_RS06860	COG2204	response regulator
FYB61_RS06865	COG0583	DNA-binding transcription factor activity
FYB61_RS06870	COG1741	Belongs to the pirin family
FYB61_RS06875	COG1741	Belongs to the pirin family
FYB61_RS06880	COG3842	ATPase activity
FYB61_RS06890	COG1840	ABC-type Fe3 transport system, periplasmic component
FYB61_RS06900	COG0583	DNA-binding transcription factor activity
FYB61_RS06905	COG2814	Major facilitator Superfamily
FYB61_RS06910	COG0656	L-ascorbic acid biosynthetic process
FYB61_RS06915	COG3468	outer membrane autotransporter barrel domain protein
FYB61_RS06925	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FYB61_RS06930	COG0583	DNA-binding transcription factor activity
FYB61_RS06945	COG0783	Belongs to the Dps family
FYB61_RS06960	COG0463	Glycosyl transferase, family 2
FYB61_RS06980	COG0438	transferase activity, transferring glycosyl groups
FYB61_RS06995	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FYB61_RS07015	COG0300	oxidoreductase activity
FYB61_RS07030	COG1028	Short-chain dehydrogenase reductase Sdr
FYB61_RS07030	COG3321	synthase
FYB61_RS07030	COG0604	alcohol dehydrogenase
FYB61_RS07050	COG0395	ABC-type sugar transport system, permease component
FYB61_RS07055	COG1175	transmembrane transport
FYB61_RS07060	COG1653	transport
FYB61_RS07070	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FYB61_RS07080	COG0559	Belongs to the binding-protein-dependent transport system permease family
FYB61_RS07100	COG1794	racemase activity, acting on amino acids and derivatives
FYB61_RS07105	COG0625	glutathione transferase activity
FYB61_RS07110	COG2133	pyrroloquinoline quinone binding
FYB61_RS07135	COG2363	Small membrane protein
FYB61_RS07150	COG1464	Belongs to the NlpA lipoprotein family
FYB61_RS07160	COG0688	phosphatidylethanolamine metabolic process
FYB61_RS07185	COG0625	glutathione transferase activity
FYB61_RS07190	COG0386	Belongs to the glutathione peroxidase family
FYB61_RS07230	COG2259	Doxx family
FYB61_RS07245	COG0667	Aldo Keto reductase
FYB61_RS07290	COG1640	4-alpha-glucanotransferase
FYB61_RS07340	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FYB61_RS07365	COG0747	negative chemotaxis
FYB61_RS07370	COG0601	transmembrane transport
FYB61_RS07375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FYB61_RS07380	COG4172	Belongs to the ABC transporter superfamily
FYB61_RS07435	COG0425	Belongs to the sulfur carrier protein TusA family
FYB61_RS07460	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FYB61_RS07470	COG0642	Histidine kinase
FYB61_RS07475	COG0745	RESPONSE REGULATOR receiver
FYB61_RS07490	COG0105	UTP biosynthetic process
FYB61_RS07515	COG2976	Protein conserved in bacteria
FYB61_RS07520	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FYB61_RS07525	COG1160	GTP binding
FYB61_RS07535	COG1923	regulation of RNA biosynthetic process
FYB61_RS07540	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FYB61_RS07545	COG0330	HflC and HflK could
FYB61_RS07550	COG0330	HflC and HflK could
FYB61_RS07570	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FYB61_RS07580	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FYB61_RS07640	COG0559	Belongs to the binding-protein-dependent transport system permease family
FYB61_RS07645	COG0683	leucine binding
FYB61_RS07650	COG4638	Rieske (2fe-2S)
FYB61_RS07660	COG1024	Enoyl-CoA hydratase
FYB61_RS07670	COG0633	Ferredoxin
FYB61_RS07675	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYB61_RS07690	COG0183	Belongs to the thiolase family
FYB61_RS07700	COG4692	amylo-alpha-1,6-glucosidase activity
FYB61_RS07705	COG0583	DNA-binding transcription factor activity
FYB61_RS07725	COG1012	belongs to the aldehyde dehydrogenase family
FYB61_RS07730	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYB61_RS07745	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FYB61_RS07755	COG3829	transcription factor binding
FYB61_RS07785	COG0833	amino acid
FYB61_RS07805	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYB61_RS07810	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FYB61_RS07815	COG0439	Biotin carboxylase
FYB61_RS07830	COG0395	ABC-type sugar transport system, permease component
FYB61_RS07835	COG1176	ABC-type spermidine putrescine transport system, permease component I
FYB61_RS07850	COG1414	Transcriptional regulator
FYB61_RS07855	COG1028	Short-chain dehydrogenase reductase Sdr
FYB61_RS07865	COG2188	Transcriptional regulator
FYB61_RS07890	COG3181	Tripartite tricarboxylate transporter family receptor
FYB61_RS07895	COG0583	DNA-binding transcription factor activity
FYB61_RS07915	COG1172	Belongs to the binding-protein-dependent transport system permease family
FYB61_RS07925	COG0179	Fumarylacetoacetate (FAA) hydrolase
FYB61_RS07935	COG1228	amidohydrolase
FYB61_RS07940	COG2267	carboxylic ester hydrolase activity
FYB61_RS07965	COG0861	Integral membrane protein TerC family
FYB61_RS07970	COG1028	Short-chain dehydrogenase reductase Sdr
FYB61_RS07985	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FYB61_RS08025	COG3119	arylsulfatase activity
FYB61_RS08045	COG2197	response regulator
FYB61_RS08055	COG2944	sequence-specific DNA binding
FYB61_RS08060	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
FYB61_RS08065	COG0625	glutathione transferase activity
FYB61_RS08080	COG3119	arylsulfatase activity
FYB61_RS08095	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYB61_RS08100	COG0183	Belongs to the thiolase family
FYB61_RS08115	COG1028	Short-chain dehydrogenase reductase Sdr
FYB61_RS08120	COG0583	DNA-binding transcription factor activity
FYB61_RS08125	COG3181	Tripartite tricarboxylate transporter family receptor
FYB61_RS08135	COG1024	Enoyl-CoA hydratase
FYB61_RS08145	COG3181	Tripartite tricarboxylate transporter family receptor
FYB61_RS08150	COG1024	Enoyl-CoA hydratase
FYB61_RS08150	COG1250	3-hydroxyacyl-CoA dehydrogenase
FYB61_RS08160	COG1454	alcohol dehydrogenase
FYB61_RS08165	COG0824	Thioesterase
FYB61_RS08190	COG0431	NADPH-dependent FMN reductase
FYB61_RS08220	COG1028	Short-chain dehydrogenase reductase Sdr
FYB61_RS08225	COG0583	DNA-binding transcription factor activity
FYB61_RS08250	COG0330	HflC and HflK could
FYB61_RS08265	COG3043	anaerobic respiration
FYB61_RS08270	COG3005	denitrification pathway
FYB61_RS08305	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FYB61_RS08335	COG4948	Mandelate Racemase Muconate Lactonizing
FYB61_RS08340	COG3181	Tripartite tricarboxylate transporter family receptor
FYB61_RS08370	COG0583	DNA-binding transcription factor activity
FYB61_RS08390	COG1695	Transcriptional regulator
FYB61_RS08400	COG3568	Endonuclease Exonuclease Phosphatase
FYB61_RS08410	COG0392	lysyltransferase activity
FYB61_RS08425	COG1546	Belongs to the CinA family
FYB61_RS08425	COG1058	Belongs to the CinA family
FYB61_RS08445	COG4575	ribosome binding
FYB61_RS08450	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FYB61_RS08460	COG1028	Short-chain dehydrogenase reductase Sdr
FYB61_RS08515	COG0028	Belongs to the TPP enzyme family
FYB61_RS08520	COG2204	response regulator
FYB61_RS08525	COG2204	response regulator
FYB61_RS08570	COG0861	Integral membrane protein TerC family
FYB61_RS08575	COG0861	Integral membrane protein TerC family
FYB61_RS08580	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FYB61_RS08585	COG0045	succinate-CoA ligase (ADP-forming) activity
FYB61_RS08605	COG2137	regulation of response to DNA damage stimulus
FYB61_RS08610	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FYB61_RS08620	COG0642	Histidine kinase
FYB61_RS08630	COG1024	Enoyl-CoA hydratase
FYB61_RS08630	COG1250	3-hydroxyacyl-CoA dehydrogenase
FYB61_RS08635	COG3842	ATPase activity
FYB61_RS08650	COG1028	Short-chain dehydrogenase reductase Sdr
FYB61_RS08665	COG0183	Belongs to the thiolase family
FYB61_RS08670	COG0583	DNA-binding transcription factor activity
FYB61_RS08675	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYB61_RS08690	COG0540	Belongs to the ATCase OTCase family
FYB61_RS08725	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FYB61_RS08740	COG1522	sequence-specific DNA binding
FYB61_RS08750	COG2367	Beta-lactamase
FYB61_RS08765	COG0500	methyltransferase
FYB61_RS08805	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FYB61_RS08810	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FYB61_RS08830	COG0004	ammonium transporteR
FYB61_RS08845	COG1309	transcriptional regulator
FYB61_RS08880	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FYB61_RS08880	COG0506	proline dehydrogenase activity
FYB61_RS08880	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FYB61_RS08890	COG3008	intermembrane lipid transfer
FYB61_RS08890	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FYB61_RS08895	COG2995	paraquat-inducible protein a
FYB61_RS08900	COG0542	response to heat
FYB61_RS08905	COG4953	penicillin-binding protein 1C
FYB61_RS08920	COG1278	Cold shock
FYB61_RS08930	COG0183	Belongs to the thiolase family
FYB61_RS08935	COG0038	chloride channel
FYB61_RS08940	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FYB61_RS08950	COG0811	peptide transport
FYB61_RS08955	COG0848	biopolymer transport protein
FYB61_RS08965	COG2835	tetraacyldisaccharide 4'-kinase activity
FYB61_RS08985	COG0728	peptidoglycan biosynthetic process
FYB61_RS08995	COG0268	Binds directly to 16S ribosomal RNA
FYB61_RS09015	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FYB61_RS09020	COG2186	Transcriptional regulator
FYB61_RS09040	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FYB61_RS09050	COG0583	DNA-binding transcription factor activity
FYB61_RS09065	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FYB61_RS09075	COG3158	transport of potassium into the cell
FYB61_RS09080	COG0642	Histidine kinase
FYB61_RS09110	COG0776	regulation of translation
FYB61_RS09115	COG3128	pkhd-type hydroxylase
FYB61_RS09125	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FYB61_RS09130	COG0557	exoribonuclease II activity
FYB61_RS09155	COG0679	Auxin Efflux Carrier
FYB61_RS09165	COG0069	glutamate synthase activity
FYB61_RS09170	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FYB61_RS09180	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
FYB61_RS09220	COG3706	GGDEF domain
FYB61_RS09255	COG3909	cytochrome
FYB61_RS09260	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FYB61_RS09265	COG0625	glutathione transferase activity
FYB61_RS09270	COG0730	response to heat
FYB61_RS09280	COG0583	DNA-binding transcription factor activity
FYB61_RS09320	COG2819	hydrolase of the alpha beta superfamily
FYB61_RS09325	COG0247	lactate metabolic process
FYB61_RS09335	COG0277	FAD linked oxidase domain protein
FYB61_RS09340	COG0277	FAD linked oxidase domain protein
FYB61_RS09345	COG3064	Membrane
FYB61_RS09345	COG3210	domain, Protein
FYB61_RS09345	COG3210	domain, Protein
FYB61_RS09345	COG3064	Membrane
FYB61_RS09345	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
FYB61_RS09345	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
FYB61_RS09350	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FYB61_RS09355	COG0312	modulator of DNA gyrase
FYB61_RS09375	COG0308	aminopeptidase N
FYB61_RS09380	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FYB61_RS09400	COG0436	Aminotransferase
FYB61_RS09405	COG3737	Protein of unknown function (DUF498/DUF598)
FYB61_RS09410	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FYB61_RS09415	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FYB61_RS09420	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FYB61_RS09430	COG0305	Participates in initiation and elongation during chromosome replication
FYB61_RS09450	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FYB61_RS09455	COG2965	DNA replication, synthesis of RNA primer
FYB61_RS09460	COG0360	Binds together with S18 to 16S ribosomal RNA
FYB61_RS09465	COG1469	GTP cyclohydrolase I activity
FYB61_RS09475	COG0142	geranyltranstransferase activity
FYB61_RS09480	COG1722	exodeoxyribonuclease VII activity
FYB61_RS09490	COG3181	Tripartite tricarboxylate transporter family receptor
FYB61_RS09525	COG1840	ABC-type Fe3 transport system, periplasmic component
FYB61_RS09530	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FYB61_RS09535	COG1178	ABC-type Fe3 transport system permease component
FYB61_RS09540	COG3842	ATPase activity
FYB61_RS09545	COG0583	DNA-binding transcription factor activity
FYB61_RS09565	COG0501	Belongs to the peptidase M48B family
FYB61_RS09575	COG0697	spore germination
FYB61_RS09585	COG1846	Transcriptional regulator
FYB61_RS09605	COG0473	3-isopropylmalate dehydrogenase activity
FYB61_RS09615	COG0747	negative chemotaxis
FYB61_RS09625	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FYB61_RS09635	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FYB61_RS09660	COG1012	belongs to the aldehyde dehydrogenase family
FYB61_RS09670	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FYB61_RS09675	COG0433	COG0433 Predicted ATPase
FYB61_RS09685	COG0151	Belongs to the GarS family
FYB61_RS09700	COG0799	negative regulation of ribosome biogenesis
FYB61_RS09715	COG3468	outer membrane autotransporter barrel domain protein
FYB61_RS09755	COG0385	Bile acid
FYB61_RS09760	COG0427	acetyl-CoA hydrolase
FYB61_RS09765	COG0583	DNA-binding transcription factor activity
FYB61_RS09770	COG1511	domain protein
FYB61_RS09770	COG3264	Mechanosensitive ion channel
FYB61_RS09785	COG0730	response to heat
FYB61_RS09790	COG0697	spore germination
FYB61_RS09825	COG2885	chlorophyll binding
FYB61_RS09845	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FYB61_RS09850	COG3384	dioxygenase
FYB61_RS09865	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FYB61_RS09870	COG3474	cytochrome
FYB61_RS09935	COG4964	Belongs to the GSP D family
FYB61_RS09985	COG4172	Belongs to the ABC transporter superfamily
FYB61_RS09990	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FYB61_RS09995	COG0601	transmembrane transport
FYB61_RS10000	COG0747	negative chemotaxis
FYB61_RS10010	COG0598	Magnesium transport protein CorA
FYB61_RS10030	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FYB61_RS10040	COG0483	inositol monophosphate 1-phosphatase activity
FYB61_RS10065	COG1045	serine acetyltransferase
FYB61_RS10070	COG0166	Belongs to the GPI family
FYB61_RS10085	COG2197	response regulator
FYB61_RS10100	COG0183	Belongs to the thiolase family
FYB61_RS10115	COG1024	Enoyl-CoA hydratase
FYB61_RS10115	COG1250	3-hydroxyacyl-CoA dehydrogenase
FYB61_RS10120	COG0183	Belongs to the thiolase family
FYB61_RS10130	COG0318	PFAM AMP-dependent synthetase and ligase
FYB61_RS10140	COG3181	Tripartite tricarboxylate transporter family receptor
FYB61_RS10155	COG1017	nitric oxide dioxygenase activity
FYB61_RS10155	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FYB61_RS10160	COG2010	Cytochrome c
FYB61_RS10160	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FYB61_RS10165	COG1335	isochorismatase
FYB61_RS10170	COG2309	aminopeptidase activity
FYB61_RS10175	COG0596	Alpha beta hydrolase
FYB61_RS10185	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FYB61_RS10190	COG2080	2 iron, 2 sulfur cluster binding
FYB61_RS10220	COG1846	Transcriptional regulator
FYB61_RS10240	COG0726	polysaccharide deacetylase
FYB61_RS10240	COG1649	PFAM Uncharacterised BCR, COG1649
FYB61_RS10245	COG1215	transferase activity, transferring glycosyl groups
FYB61_RS10255	COG1902	pentaerythritol trinitrate reductase activity
FYB61_RS10280	COG0251	oxidation-reduction process
FYB61_RS10290	COG1832	CoA-binding protein
FYB61_RS10295	COG1414	Transcriptional regulator
FYB61_RS10300	COG1902	pentaerythritol trinitrate reductase activity
FYB61_RS10300	COG0446	pyridine nucleotide-disulphide oxidoreductase
FYB61_RS10310	COG3842	ATPase activity
FYB61_RS10335	COG0583	DNA-binding transcription factor activity
FYB61_RS10345	COG1028	Short-chain dehydrogenase reductase Sdr
FYB61_RS10355	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FYB61_RS10370	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FYB61_RS10395	COG0527	aspartate kinase activity
FYB61_RS10405	COG0825	malonyl-CoA metabolic process
FYB61_RS10420	COG3063	Type IV pilus biogenesis stability protein PilW
FYB61_RS10440	COG1253	flavin adenine dinucleotide binding
FYB61_RS10465	COG0668	transmembrane transport
FYB61_RS10500	COG3360	Dodecin
FYB61_RS10510	COG2850	peptidyl-arginine hydroxylation
FYB61_RS10520	COG3539	Fimbrial protein
FYB61_RS10525	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
FYB61_RS10530	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FYB61_RS10535	COG1994	Peptidase M50
FYB61_RS10540	COG0009	L-threonylcarbamoyladenylate synthase
FYB61_RS10545	COG2321	neutral zinc metallopeptidase
FYB61_RS10590	COG1366	Belongs to the anti-sigma-factor antagonist family
FYB61_RS10595	COG2172	sigma factor antagonist activity
FYB61_RS10600	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FYB61_RS10610	COG2208	phosphoserine phosphatase activity
FYB61_RS10610	COG2770	Histidine kinase
FYB61_RS10645	COG4792	protein secretion
FYB61_RS10650	COG4791	protein targeting
FYB61_RS10655	COG4794	Type iii secretion
FYB61_RS10695	COG4669	(LipO)protein
FYB61_RS10795	COG0251	oxidation-reduction process
FYB61_RS10835	COG1028	Short-chain dehydrogenase reductase Sdr
FYB61_RS10885	COG0179	Fumarylacetoacetate (FAA) hydrolase
FYB61_RS10900	COG0583	DNA-binding transcription factor activity
FYB61_RS10905	COG3971	2-oxopent-4-enoate hydratase activity
FYB61_RS10935	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FYB61_RS10950	COG0511	ligase activity, forming carbon-carbon bonds
FYB61_RS10960	COG0439	Biotin carboxylase
FYB61_RS10965	COG2188	Transcriptional regulator
FYB61_RS10990	COG0511	ligase activity, forming carbon-carbon bonds
FYB61_RS11000	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FYB61_RS11010	COG1012	belongs to the aldehyde dehydrogenase family
FYB61_RS11020	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
FYB61_RS11045	COG1132	(ABC) transporter
FYB61_RS11055	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FYB61_RS11095	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FYB61_RS11130	COG0583	DNA-binding transcription factor activity
FYB61_RS11150	COG3181	Tripartite tricarboxylate transporter family receptor
FYB61_RS11180	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FYB61_RS11195	COG1126	abc transporter atp-binding protein
FYB61_RS11200	COG0765	amino acid transport
FYB61_RS11205	COG4597	amino acid ABC transporter
FYB61_RS11210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYB61_RS11215	COG1473	amidohydrolase
FYB61_RS11220	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FYB61_RS11225	COG1522	sequence-specific DNA binding
FYB61_RS11235	COG0179	Fumarylacetoacetate (FAA) hydrolase
FYB61_RS11245	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FYB61_RS11250	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FYB61_RS11255	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FYB61_RS11275	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FYB61_RS11280	COG0154	amidase activity
FYB61_RS11290	COG1137	ATPase activity
FYB61_RS11320	COG1250	3-hydroxyacyl-CoA dehydrogenase
FYB61_RS11325	COG2072	flavoprotein involved in K transport
FYB61_RS11360	COG0559	Belongs to the binding-protein-dependent transport system permease family
FYB61_RS11390	COG0559	Belongs to the binding-protein-dependent transport system permease family
FYB61_RS11490	COG0248	Ppx GppA phosphatase
FYB61_RS11510	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FYB61_RS11520	COG1534	Rna-binding protein
FYB61_RS11530	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FYB61_RS11535	COG0840	transmembrane signaling receptor activity
FYB61_RS11540	COG2233	PERMEase
FYB61_RS11555	COG3842	ATPase activity
FYB61_RS11565	COG0406	alpha-ribazole phosphatase activity
FYB61_RS11570	COG4221	oxidoreductase activity
FYB61_RS11585	COG0084	hydrolase, TatD family'
FYB61_RS11590	COG1136	(ABC) transporter
FYB61_RS11605	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FYB61_RS11615	COG1028	Short-chain dehydrogenase reductase Sdr
FYB61_RS11635	COG1022	Amp-dependent synthetase and ligase
FYB61_RS11665	COG1024	Enoyl-CoA hydratase
FYB61_RS11680	COG0633	Ferredoxin
FYB61_RS11695	COG0316	Belongs to the HesB IscA family
FYB61_RS11700	COG0822	iron-sulfur transferase activity
FYB61_RS11705	COG1104	cysteine desulfurase activity
FYB61_RS11715	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FYB61_RS11735	COG3468	outer membrane autotransporter barrel domain protein
FYB61_RS11745	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FYB61_RS11760	COG1960	acyl-CoA dehydrogenase activity
FYB61_RS11765	COG1028	Short-chain dehydrogenase reductase Sdr
FYB61_RS11780	COG1024	Enoyl-CoA hydratase
FYB61_RS11795	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYB61_RS11800	COG0583	DNA-binding transcription factor activity
FYB61_RS11805	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FYB61_RS11815	COG0740	serine-type endopeptidase activity
FYB61_RS11830	COG1278	Cold shock
FYB61_RS11840	COG1278	Cold shock
FYB61_RS11870	COG0436	Aminotransferase
FYB61_RS11885	COG2890	protein-(glutamine-N5) methyltransferase activity
FYB61_RS11890	COG0488	(ABC) transporter
FYB61_RS11895	COG4771	TonB-dependent receptor
FYB61_RS11900	COG0210	DNA helicase
FYB61_RS11915	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FYB61_RS11915	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FYB61_RS11920	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FYB61_RS11925	COG0196	riboflavin kinase activity
FYB61_RS11935	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FYB61_RS11940	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FYB61_RS11950	COG1522	sequence-specific DNA binding
FYB61_RS11975	COG1126	abc transporter atp-binding protein
FYB61_RS11980	COG0765	amino acid transport
FYB61_RS11985	COG0765	amino acid transport
FYB61_RS11990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYB61_RS12000	COG2423	ornithine cyclodeaminase activity
FYB61_RS12005	COG1764	response to oxidative stress
FYB61_RS12015	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FYB61_RS12020	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FYB61_RS12035	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FYB61_RS12040	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FYB61_RS12045	COG2197	response regulator
FYB61_RS12055	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FYB61_RS12115	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FYB61_RS12130	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FYB61_RS12155	COG1122	ATPase activity
FYB61_RS12185	COG0437	4 iron, 4 sulfur cluster binding
FYB61_RS12190	COG3383	formate dehydrogenase (NAD+) activity
FYB61_RS12190	COG0243	molybdopterin cofactor binding
FYB61_RS12220	COG0489	protein tyrosine kinase activity
FYB61_RS12225	COG0746	molybdenum cofactor guanylyltransferase activity
FYB61_RS12230	COG0303	'Molybdopterin
FYB61_RS12235	COG1763	Mo-molybdopterin cofactor biosynthetic process
FYB61_RS12250	COG5001	Diguanylate cyclase
FYB61_RS12255	COG2205	protein histidine kinase activity
FYB61_RS12260	COG0745	RESPONSE REGULATOR receiver
FYB61_RS12275	COG1295	ribonuclease BN
FYB61_RS12285	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FYB61_RS12315	COG4964	Belongs to the GSP D family
FYB61_RS12355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FYB61_RS12390	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FYB61_RS12395	COG3395	kinase activity
FYB61_RS12435	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FYB61_RS12440	COG2358	TRAP transporter, solute receptor (TAXI family
FYB61_RS12450	COG2311	Membrane
FYB61_RS12475	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FYB61_RS12490	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FYB61_RS12495	COG1760	l-serine dehydratase
FYB61_RS12500	COG1283	sodium-dependent phosphate transmembrane transporter activity
FYB61_RS12505	COG0412	Dienelactone hydrolase
FYB61_RS12520	COG1611	Belongs to the LOG family
FYB61_RS12555	COG0195	Participates in both transcription termination and antitermination
FYB61_RS12555	COG2251	uridine kinase activity
FYB61_RS12565	COG1187	pseudouridine synthase activity
FYB61_RS12570	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FYB61_RS12580	COG0583	DNA-binding transcription factor activity
FYB61_RS12590	COG0523	cobalamin synthesis protein
FYB61_RS12610	COG0625	glutathione transferase activity
FYB61_RS12615	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FYB61_RS12620	COG1047	Peptidyl-prolyl cis-trans
FYB61_RS12680	COG2304	oxidoreductase activity
FYB61_RS12700	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FYB61_RS12705	COG1562	ergosterol biosynthetic process
FYB61_RS12710	COG1562	ergosterol biosynthetic process
FYB61_RS12715	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
FYB61_RS12715	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
FYB61_RS12735	COG1131	(ABC) transporter
FYB61_RS12770	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
FYB61_RS12785	COG5564	TIM-barrel signal transduction protein
FYB61_RS12800	COG3468	outer membrane autotransporter barrel domain protein
FYB61_RS12810	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FYB61_RS12825	COG0494	nUDIX hydrolase
FYB61_RS12830	COG3530	Putative quorum-sensing-regulated virulence factor
FYB61_RS12840	COG1595	DNA-templated transcription, initiation
FYB61_RS12845	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FYB61_RS12880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYB61_RS12885	COG0765	amino acid transport
FYB61_RS12890	COG0765	amino acid transport
FYB61_RS12920	COG2841	Protein conserved in bacteria
FYB61_RS12925	COG2814	Major facilitator Superfamily
FYB61_RS12940	COG0628	permease
FYB61_RS12945	COG0842	Transport permease protein
FYB61_RS12950	COG1131	(ABC) transporter
FYB61_RS12995	COG3278	Belongs to the heme-copper respiratory oxidase family
FYB61_RS13025	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FYB61_RS13025	COG4106	trans-aconitate 2-methyltransferase activity
FYB61_RS13030	COG1380	Effector of murein hydrolase LrgA
FYB61_RS13035	COG1346	cytolysis
FYB61_RS13045	COG2224	Isocitrate lyase
FYB61_RS13060	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FYB61_RS13080	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FYB61_RS13095	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYB61_RS13120	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FYB61_RS13135	COG2032	superoxide dismutase activity
FYB61_RS13145	COG0318	PFAM AMP-dependent synthetase and ligase
FYB61_RS13150	COG1024	Enoyl-CoA hydratase
FYB61_RS13160	COG1802	Transcriptional regulator
FYB61_RS13170	COG0183	Belongs to the thiolase family
FYB61_RS13175	COG1942	4-Oxalocrotonate Tautomerase
FYB61_RS13185	COG4176	ABC-type proline glycine betaine transport system permease component
FYB61_RS13195	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FYB61_RS13200	COG2814	Major facilitator Superfamily
FYB61_RS13205	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FYB61_RS13210	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FYB61_RS13230	COG2814	Major facilitator Superfamily
FYB61_RS13260	COG0154	amidase activity
FYB61_RS13265	COG1250	3-hydroxyacyl-CoA dehydrogenase
FYB61_RS13305	COG1530	ribonuclease E activity
FYB61_RS13310	COG0077	Prephenate dehydratase
FYB61_RS13330	COG0859	PFAM glycosyl transferase family 9
FYB61_RS13355	COG2194	sulfuric ester hydrolase activity
FYB61_RS13360	COG0438	transferase activity, transferring glycosyl groups
FYB61_RS13365	COG0463	Glycosyl transferase, family 2
FYB61_RS13370	COG0726	polysaccharide deacetylase
FYB61_RS13375	COG0438	transferase activity, transferring glycosyl groups
FYB61_RS13390	COG1643	Atp-dependent helicase
FYB61_RS13395	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FYB61_RS13395	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FYB61_RS13400	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FYB61_RS13410	COG0704	Plays a role in the regulation of phosphate uptake
FYB61_RS13420	COG1960	acyl-CoA dehydrogenase activity
FYB61_RS13445	COG1177	transmembrane transport
FYB61_RS13450	COG1176	ABC-type spermidine putrescine transport system, permease component I
FYB61_RS13455	COG3842	ATPase activity
FYB61_RS13460	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FYB61_RS13475	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FYB61_RS13480	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FYB61_RS13495	COG3539	Fimbrial protein
FYB61_RS13500	COG3539	Fimbrial protein
FYB61_RS13515	COG2050	protein possibly involved in aromatic compounds catabolism
FYB61_RS13520	COG1024	Enoyl-CoA hydratase
FYB61_RS13525	COG1012	belongs to the aldehyde dehydrogenase family
FYB61_RS13530	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FYB61_RS13535	COG2151	metal-sulfur cluster biosynthetic enzyme
FYB61_RS13540	COG3396	Phenylacetate-CoA oxygenase
FYB61_RS13545	COG3460	Phenylacetate-CoA oxygenase
FYB61_RS13550	COG3396	Phenylacetate-CoA oxygenase
FYB61_RS13565	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FYB61_RS13570	COG0501	Belongs to the peptidase M48B family
FYB61_RS13575	COG1162	GTPase activity
FYB61_RS13580	COG0667	Aldo Keto reductase
FYB61_RS13590	COG0335	large ribosomal subunit rRNA binding
FYB61_RS13620	COG0175	sulfate reduction
FYB61_RS13630	COG4208	sulfate ABC transporter
FYB61_RS13650	COG0602	queuosine metabolic process
FYB61_RS13655	COG0720	synthase
FYB61_RS13660	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FYB61_RS13665	COG0235	Class ii aldolase
FYB61_RS13690	COG1566	PFAM secretion protein HlyD family protein
FYB61_RS13700	COG0400	carboxylic ester hydrolase activity
FYB61_RS13725	COG1959	2 iron, 2 sulfur cluster binding
FYB61_RS13765	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FYB61_RS13780	COG0667	Aldo Keto reductase
FYB61_RS13790	COG5265	(ABC) transporter
FYB61_RS13820	COG3468	outer membrane autotransporter barrel domain protein
FYB61_RS13825	COG3468	outer membrane autotransporter barrel domain protein
FYB61_RS13845	COG3447	MASE1 domain protein
FYB61_RS13845	COG5002	protein histidine kinase activity
FYB61_RS13845	COG5001	Diguanylate cyclase
FYB61_RS13850	COG0840	transmembrane signaling receptor activity
FYB61_RS13855	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FYB61_RS13860	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FYB61_RS13890	COG0583	DNA-binding transcription factor activity
FYB61_RS13900	COG2814	Major facilitator Superfamily
FYB61_RS13925	COG2084	Dehydrogenase
FYB61_RS13930	COG3181	Tripartite tricarboxylate transporter family receptor
FYB61_RS13940	COG1253	flavin adenine dinucleotide binding
FYB61_RS13955	COG2988	succinylglutamate desuccinylase activity
FYB61_RS13980	COG0861	Integral membrane protein TerC family
FYB61_RS13990	COG1595	DNA-templated transcription, initiation
FYB61_RS14020	COG3189	MarR family transcriptional regulator
FYB61_RS14050	COG0028	Belongs to the TPP enzyme family
FYB61_RS14060	COG1012	belongs to the aldehyde dehydrogenase family
FYB61_RS14065	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FYB61_RS14075	COG1126	abc transporter atp-binding protein
FYB61_RS14100	COG0084	hydrolase, TatD family'
FYB61_RS14105	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FYB61_RS14110	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FYB61_RS14115	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FYB61_RS14140	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FYB61_RS14145	COG1960	acyl-CoA dehydrogenase activity
FYB61_RS14155	COG2867	negative regulation of translational initiation
FYB61_RS14170	COG0330	HflC and HflK could
FYB61_RS14195	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FYB61_RS14200	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FYB61_RS14225	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
FYB61_RS14230	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FYB61_RS14235	COG0750	zinc metalloprotease
FYB61_RS14250	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FYB61_RS14255	COG0233	cytoplasmic translational termination
FYB61_RS14270	COG0052	Belongs to the universal ribosomal protein uS2 family
FYB61_RS14275	COG0024	Methionine aminopeptidase
FYB61_RS14310	COG0285	dihydrofolate synthase activity
FYB61_RS14340	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FYB61_RS14350	COG1677	Flagellar hook-basal body complex protein FliE
FYB61_RS14360	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FYB61_RS14365	COG1317	bacterial-type flagellum organization
FYB61_RS14370	COG1157	protein secretion by the type III secretion system
FYB61_RS14385	COG1580	Controls the rotational direction of flagella during chemotaxis
FYB61_RS14405	COG1338	Plays a role in the flagellum-specific transport system
FYB61_RS14425	COG0840	transmembrane signaling receptor activity
FYB61_RS14435	COG1256	bacterial-type flagellum assembly
FYB61_RS14465	COG1749	Flagellar hook protein flgE
FYB61_RS14475	COG1558	bacterial-type flagellum-dependent cell motility
FYB61_RS14480	COG1815	bacterial-type flagellum-dependent cell motility
FYB61_RS14515	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FYB61_RS14520	COG0745	RESPONSE REGULATOR receiver
FYB61_RS14530	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FYB61_RS14535	COG0840	transmembrane signaling receptor activity
FYB61_RS14545	COG0643	Histidine kinase
FYB61_RS14545	COG2198	Histidine kinase
FYB61_RS14550	COG0745	RESPONSE REGULATOR receiver
FYB61_RS14580	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FYB61_RS14585	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FYB61_RS14590	COG0508	dehydrogenase complex catalyzes the overall conversion of
FYB61_RS14595	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FYB61_RS14605	COG4566	intracellular signal transduction
FYB61_RS14610	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FYB61_RS14615	COG0339	signal peptide processing
FYB61_RS14620	COG1999	signal sequence binding
FYB61_RS14640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYB61_RS14650	COG1187	pseudouridine synthase activity
FYB61_RS14655	COG3161	chorismate lyase activity
FYB61_RS14670	COG1280	lysine exporter protein (LysE YggA)
FYB61_RS14685	COG0601	transmembrane transport
FYB61_RS14690	COG0747	negative chemotaxis
FYB61_RS14735	COG0668	transmembrane transport
FYB61_RS14740	COG0165	Argininosuccinate lyase
FYB61_RS14750	COG0789	Transcriptional regulator
FYB61_RS14760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYB61_RS14770	COG1126	abc transporter atp-binding protein
FYB61_RS14780	COG2346	COG2346, Truncated hemoglobins
FYB61_RS14840	COG1335	isochorismatase
FYB61_RS14865	COG2837	iron assimilation
FYB61_RS14895	COG4691	Plasmid stability protein
FYB61_RS14930	COG0583	DNA-binding transcription factor activity
FYB61_RS14935	COG2814	Major facilitator Superfamily
FYB61_RS14945	COG0501	Belongs to the peptidase M48B family
FYB61_RS14955	COG0583	DNA-binding transcription factor activity
FYB61_RS14965	COG2188	Transcriptional regulator
FYB61_RS14980	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FYB61_RS14990	COG3181	Tripartite tricarboxylate transporter family receptor
FYB61_RS14995	COG0129	dihydroxy-acid dehydratase activity
FYB61_RS15010	COG0129	dihydroxy-acid dehydratase activity
FYB61_RS15020	COG3622	Belongs to the hyi family
FYB61_RS15025	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FYB61_RS15030	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FYB61_RS15045	COG0583	DNA-binding transcription factor activity
FYB61_RS15050	COG1250	3-hydroxyacyl-CoA dehydrogenase
FYB61_RS15055	COG3246	L-lysine catabolic process to acetate
FYB61_RS15090	COG0697	spore germination
FYB61_RS15105	COG0625	glutathione transferase activity
FYB61_RS15125	COG1280	lysine exporter protein (LysE YggA)
FYB61_RS15130	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FYB61_RS15165	COG2207	Transcriptional regulator
FYB61_RS15205	COG1132	(ABC) transporter
FYB61_RS15230	COG0659	secondary active sulfate transmembrane transporter activity
FYB61_RS15265	COG5507	3-demethylubiquinone-9 3-methyltransferase
FYB61_RS15270	COG0384	phenazine biosynthesis protein PhzF
FYB61_RS15275	COG0583	DNA-binding transcription factor activity
FYB61_RS15280	COG2733	membrane
FYB61_RS15295	COG1012	belongs to the aldehyde dehydrogenase family
FYB61_RS15300	COG3284	Transcriptional regulator
FYB61_RS15305	COG0656	L-ascorbic acid biosynthetic process
FYB61_RS15330	COG0842	Transport permease protein
FYB61_RS15350	COG1802	Transcriptional regulator
FYB61_RS15370	COG3181	Tripartite tricarboxylate transporter family receptor
FYB61_RS15375	COG2188	Transcriptional regulator
FYB61_RS15400	COG0789	Transcriptional regulator
FYB61_RS15415	COG1609	Transcriptional regulator
FYB61_RS15420	COG4172	Belongs to the ABC transporter superfamily
FYB61_RS15430	COG0601	transmembrane transport
FYB61_RS15435	COG0747	negative chemotaxis
FYB61_RS15450	COG1280	lysine exporter protein (LysE YggA)
FYB61_RS15485	COG1012	belongs to the aldehyde dehydrogenase family
FYB61_RS15490	COG2079	MmgE PrpD family protein
FYB61_RS15510	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYB61_RS15525	COG3618	amidohydrolase
FYB61_RS15540	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FYB61_RS15555	COG0625	glutathione transferase activity
FYB61_RS15570	COG2814	Major facilitator Superfamily
FYB61_RS15575	COG0477	Major facilitator Superfamily
FYB61_RS15595	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FYB61_RS15600	COG1061	Type III restriction enzyme res subunit
FYB61_RS15640	COG2197	response regulator
FYB61_RS15645	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FYB61_RS15665	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FYB61_RS15685	COG3181	Tripartite tricarboxylate transporter family receptor
FYB61_RS15705	COG3064	Membrane
FYB61_RS15705	COG3210	domain, Protein
FYB61_RS15705	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
FYB61_RS15710	COG0047	phosphoribosylformylglycinamidine synthase activity
FYB61_RS15710	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FYB61_RS15715	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FYB61_RS15735	COG0613	PHP domain protein
FYB61_RS15765	COG0450	alkyl hydroperoxide reductase
FYB61_RS15770	COG1960	acyl-CoA dehydrogenase activity
FYB61_RS15785	COG0123	including yeast histone deacetylase and acetoin utilization protein
FYB61_RS15790	COG2951	lytic endotransglycosylase activity
FYB61_RS15810	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FYB61_RS15815	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FYB61_RS15845	COG0287	Prephenate dehydrogenase
FYB61_RS15880	COG2814	Major facilitator Superfamily
FYB61_RS15945	COG0583	DNA-binding transcription factor activity
FYB61_RS15960	COG0179	Fumarylacetoacetate (FAA) hydrolase
FYB61_RS15985	COG1053	succinate dehydrogenase
FYB61_RS15990	COG1012	belongs to the aldehyde dehydrogenase family
FYB61_RS15995	COG2079	MmgE PrpD family protein
FYB61_RS16005	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FYB61_RS16030	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
FYB61_RS16030	COG0028	Belongs to the TPP enzyme family
FYB61_RS16035	COG0436	Aminotransferase
FYB61_RS16055	COG0778	Nitroreductase
FYB61_RS16060	COG2814	Major facilitator Superfamily
FYB61_RS16065	COG3706	GGDEF domain
FYB61_RS16070	COG0589	response to stress
FYB61_RS16080	COG2951	lytic endotransglycosylase activity
FYB61_RS16085	COG2833	Protein of unknown function (DUF455)
FYB61_RS16100	COG1132	(ABC) transporter
FYB61_RS16110	COG1181	Belongs to the D-alanine--D-alanine ligase family
FYB61_RS16110	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FYB61_RS16115	COG3237	CsbD-like
FYB61_RS16125	COG2823	Periplasmic or secreted lipoprotein
FYB61_RS16145	COG0672	)-iron permease
FYB61_RS16160	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
FYB61_RS16165	COG1028	Short-chain dehydrogenase reductase Sdr
FYB61_RS16170	COG3243	poly(R)-hydroxyalkanoic acid synthase
FYB61_RS16180	COG0564	pseudouridine synthase activity
FYB61_RS16190	COG1199	ATP-dependent helicase activity
FYB61_RS16195	COG2183	response to ionizing radiation
FYB61_RS16220	COG4774	siderophore transport
FYB61_RS16230	COG1595	DNA-templated transcription, initiation
FYB61_RS16235	COG2175	clavaminate synthase activity
FYB61_RS16245	COG3181	Tripartite tricarboxylate transporter family receptor
FYB61_RS16250	COG0583	DNA-binding transcription factor activity
FYB61_RS16255	COG1028	Short-chain dehydrogenase reductase Sdr
FYB61_RS16260	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FYB61_RS16265	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FYB61_RS16270	COG0508	dehydrogenase complex catalyzes the overall conversion of
FYB61_RS16275	COG0567	Dehydrogenase, E1 component
FYB61_RS16285	COG1522	sequence-specific DNA binding
FYB61_RS16295	COG0281	malic enzyme
FYB61_RS16295	COG0280	phosphate acetyltransferase
FYB61_RS16300	COG3539	Fimbrial protein
FYB61_RS16315	COG0372	Belongs to the citrate synthase family
FYB61_RS16320	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FYB61_RS16325	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FYB61_RS16330	COG1053	succinate dehydrogenase
FYB61_RS16335	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FYB61_RS16340	COG2009	succinate dehydrogenase
FYB61_RS16345	COG2188	Transcriptional regulator
FYB61_RS16350	COG0039	L-malate dehydrogenase activity
FYB61_RS16370	COG2828	Protein conserved in bacteria
FYB61_RS16405	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FYB61_RS16415	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FYB61_RS16450	COG0148	phosphopyruvate hydratase activity
FYB61_RS16460	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FYB61_RS16465	COG0504	CTP synthase activity
FYB61_RS16485	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FYB61_RS16495	COG0747	negative chemotaxis
FYB61_RS16500	COG4172	Belongs to the ABC transporter superfamily
FYB61_RS16505	COG1446	asparaginase
FYB61_RS16535	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FYB61_RS16550	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FYB61_RS16555	COG0697	spore germination
FYB61_RS16560	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FYB61_RS16570	COG3193	protein, possibly involved in utilization of glycolate and propanediol
FYB61_RS16575	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FYB61_RS16580	COG0791	NLP P60 protein
FYB61_RS16590	COG0583	DNA-binding transcription factor activity
FYB61_RS16605	COG0583	DNA-binding transcription factor activity
FYB61_RS16630	COG0670	Belongs to the BI1 family
FYB61_RS16635	COG3181	Tripartite tricarboxylate transporter family receptor
FYB61_RS16645	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FYB61_RS16655	COG1381	Involved in DNA repair and RecF pathway recombination
FYB61_RS16660	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FYB61_RS16665	COG0571	ribonuclease III activity
FYB61_RS16670	COG0681	Belongs to the peptidase S26 family
FYB61_RS16680	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FYB61_RS16705	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FYB61_RS16710	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FYB61_RS16735	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FYB61_RS16740	COG1399	metal-binding, possibly nucleic acid-binding protein
FYB61_RS16755	COG3023	N-Acetylmuramoyl-L-alanine amidase
FYB61_RS16765	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FYB61_RS16770	COG0546	phosphoglycolate phosphatase activity
FYB61_RS16780	COG1530	ribonuclease E activity
FYB61_RS16790	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FYB61_RS16795	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FYB61_RS16820	COG3228	Belongs to the MtfA family
FYB61_RS16830	COG0251	oxidation-reduction process
FYB61_RS16840	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FYB61_RS16855	COG2878	Part of a membrane complex involved in electron transport
FYB61_RS16860	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FYB61_RS16895	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FYB61_RS16920	COG1268	BioY protein
FYB61_RS16925	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FYB61_RS16930	COG1122	ATPase activity
FYB61_RS16935	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FYB61_RS16945	COG0271	Belongs to the BolA IbaG family
FYB61_RS16950	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FYB61_RS16965	COG1196	nuclear chromosome segregation
FYB61_RS16970	COG0477	Major facilitator Superfamily
FYB61_RS16975	COG1573	uracil-dna glycosylase
FYB61_RS16980	COG1214	PFAM Peptidase M22, glycoprotease
FYB61_RS16985	COG0745	RESPONSE REGULATOR receiver
FYB61_RS16990	COG2205	protein histidine kinase activity
FYB61_RS16995	COG0450	alkyl hydroperoxide reductase
FYB61_RS17000	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FYB61_RS17015	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FYB61_RS17025	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FYB61_RS17030	COG0560	Phosphoserine phosphatase
FYB61_RS17035	COG0583	DNA-binding transcription factor activity
FYB61_RS17040	COG3181	Tripartite tricarboxylate transporter family receptor
FYB61_RS17045	COG0028	Belongs to the TPP enzyme family
FYB61_RS17070	COG4774	siderophore transport
FYB61_RS17080	COG1007	ATP synthesis coupled electron transport
FYB61_RS17095	COG0713	ATP synthesis coupled electron transport
FYB61_RS17105	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FYB61_RS17110	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FYB61_RS17115	COG1034	ATP synthesis coupled electron transport
FYB61_RS17125	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FYB61_RS17140	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FYB61_RS17145	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FYB61_RS17150	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FYB61_RS17170	COG0671	phosphoesterase, PA-phosphatase related
FYB61_RS17180	COG1597	lipid kinase activity
FYB61_RS17185	COG0583	DNA-binding transcription factor activity
FYB61_RS17190	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FYB61_RS17195	COG1733	regulation of RNA biosynthetic process
FYB61_RS17200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYB61_RS17220	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
FYB61_RS17240	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FYB61_RS17260	COG3608	succinylglutamate desuccinylase aspartoacylase
FYB61_RS17265	COG0626	cystathionine gamma-synthase activity
FYB61_RS17270	COG0583	DNA-binding transcription factor activity
FYB61_RS17280	COG3181	Tripartite tricarboxylate transporter family receptor
FYB61_RS17285	COG0165	Argininosuccinate lyase
FYB61_RS17300	COG3799	methylaspartate ammonia-lyase activity
FYB61_RS17310	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FYB61_RS17320	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FYB61_RS17325	COG0149	triose-phosphate isomerase activity
FYB61_RS17345	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FYB61_RS17355	COG1185	polyribonucleotide nucleotidyltransferase activity
FYB61_RS17360	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FYB61_RS17370	COG1183	phosphatidylcholine synthase activity
FYB61_RS17380	COG0440	acetolactate synthase activity
FYB61_RS17385	COG0028	Belongs to the TPP enzyme family
FYB61_RS17390	COG1289	transmembrane transporter activity
FYB61_RS17400	COG3022	response to hydroperoxide
FYB61_RS17405	COG1028	Short-chain dehydrogenase reductase Sdr
FYB61_RS17420	COG3486	L-lysine 6-monooxygenase (NADPH) activity
FYB61_RS17450	COG2814	Major facilitator Superfamily
FYB61_RS17470	COG3706	GGDEF domain
FYB61_RS17505	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FYB61_RS17515	COG1674	ftsk spoiiie
FYB61_RS17520	COG0492	ferredoxin-NADP+ reductase activity
FYB61_RS17525	COG1193	negative regulation of DNA recombination
FYB61_RS17535	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FYB61_RS17555	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FYB61_RS17560	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FYB61_RS17565	COG2205	protein histidine kinase activity
FYB61_RS17570	COG0745	RESPONSE REGULATOR receiver
FYB61_RS17605	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FYB61_RS17625	COG0612	Peptidase, M16
FYB61_RS17645	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FYB61_RS17660	COG1420	regulation of RNA biosynthetic process
FYB61_RS17670	COG0497	DNA recombination
FYB61_RS17680	COG0735	belongs to the Fur family
FYB61_RS17685	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FYB61_RS17730	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FYB61_RS17730	COG0446	pyridine nucleotide-disulphide oxidoreductase
FYB61_RS17735	COG4311	Sarcosine oxidase, delta subunit
FYB61_RS17740	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FYB61_RS17750	COG0583	DNA-binding transcription factor activity
FYB61_RS17770	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYB61_RS17775	COG2030	dehydratase
FYB61_RS17785	COG1024	Enoyl-CoA hydratase
FYB61_RS17810	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FYB61_RS17835	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FYB61_RS17850	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FYB61_RS17860	COG0405	Gamma-glutamyltransferase
FYB61_RS17875	COG1280	lysine exporter protein (LysE YggA)
FYB61_RS17905	COG0583	DNA-binding transcription factor activity
FYB61_RS17945	COG1414	Transcriptional regulator
FYB61_RS17950	COG1058	Belongs to the CinA family
FYB61_RS17950	COG1546	Belongs to the CinA family
FYB61_RS17965	COG0513	Belongs to the DEAD box helicase family
FYB61_RS17995	COG0429	hydrolase of the alpha beta-hydrolase fold
FYB61_RS18000	COG4783	chaperone-mediated protein folding
FYB61_RS18015	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FYB61_RS18030	COG0006	proline dipeptidase activity
FYB61_RS18040	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FYB61_RS18085	COG0514	ATP-dependent DNA helicase (RecQ)
FYB61_RS18095	COG0745	RESPONSE REGULATOR receiver
FYB61_RS18110	COG1271	oxidase subunit
FYB61_RS18125	COG2894	cell division
FYB61_RS18130	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FYB61_RS18145	COG0488	(ABC) transporter
FYB61_RS18170	COG4608	Belongs to the ABC transporter superfamily
FYB61_RS18175	COG0444	Belongs to the ABC transporter superfamily
FYB61_RS18180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FYB61_RS18185	COG0601	transmembrane transport
FYB61_RS18195	COG1215	transferase activity, transferring glycosyl groups
FYB61_RS18205	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FYB61_RS18215	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FYB61_RS18230	COG0318	PFAM AMP-dependent synthetase and ligase
FYB61_RS18235	COG2188	Transcriptional regulator
FYB61_RS18240	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FYB61_RS18245	COG2814	Major facilitator Superfamily
FYB61_RS18255	COG0259	pyridoxamine-phosphate oxidase activity
FYB61_RS18260	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FYB61_RS18275	COG0583	DNA-binding transcription factor activity
FYB61_RS18280	COG1960	acyl-CoA dehydrogenase activity
FYB61_RS18290	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYB61_RS18295	COG0405	Gamma-glutamyltransferase
FYB61_RS18305	COG3181	Tripartite tricarboxylate transporter family receptor
FYB61_RS18320	COG0802	atpase or kinase
FYB61_RS18325	COG0860	N-Acetylmuramoyl-L-alanine amidase
FYB61_RS18330	COG0586	Pfam SNARE associated Golgi protein
FYB61_RS18360	COG0617	tRNA 3'-terminal CCA addition
FYB61_RS18385	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FYB61_RS18390	COG2188	Transcriptional regulator
FYB61_RS18400	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FYB61_RS18405	COG1234	tRNA 3'-trailer cleavage
FYB61_RS18410	COG1028	Short-chain dehydrogenase reductase Sdr
FYB61_RS18420	COG1028	Short-chain dehydrogenase reductase Sdr
FYB61_RS18425	COG3181	Tripartite tricarboxylate transporter family receptor
FYB61_RS18430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FYB61_RS18435	COG2301	Belongs to the HpcH HpaI aldolase family
FYB61_RS18445	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
FYB61_RS18455	COG1024	Enoyl-CoA hydratase
FYB61_RS18465	COG2188	Transcriptional regulator
FYB61_RS18470	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FYB61_RS18475	COG0066	3-isopropylmalate dehydratase activity
FYB61_RS18490	COG0752	glycyl-tRNA synthetase alpha subunit
FYB61_RS18495	COG0751	glycine-tRNA ligase activity
FYB61_RS18500	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FYB61_RS18505	COG0204	Acyl-transferase
FYB61_RS18520	COG0242	peptide deformylase activity
FYB61_RS18525	COG1960	acyl-CoA dehydrogenase activity
FYB61_RS18530	COG0700	Nucleoside recognition
FYB61_RS18535	COG0469	pyruvate kinase activity
FYB61_RS18565	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FYB61_RS18575	COG2154	pterin-4-alpha-carbinolamine dehydratase
FYB61_RS18595	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FYB61_RS18600	COG0154	amidase activity
FYB61_RS18610	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FYB61_RS18620	COG0747	negative chemotaxis
FYB61_RS18635	COG0019	diaminopimelate decarboxylase activity
FYB61_RS18650	COG3712	iron ion homeostasis
FYB61_RS18655	COG4774	siderophore transport
FYB61_RS18660	COG2353	YceI-like domain
FYB61_RS18665	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FYB61_RS18680	COG0583	DNA-binding transcription factor activity
FYB61_RS18700	COG3384	dioxygenase
FYB61_RS18705	COG0179	Fumarylacetoacetate (FAA) hydrolase
FYB61_RS18735	COG1028	Short-chain dehydrogenase reductase Sdr
FYB61_RS18740	COG1309	transcriptional regulator
FYB61_RS18745	COG2982	Protein involved in outer membrane biogenesis
FYB61_RS18750	COG2818	Glycosylase
FYB61_RS18770	COG1653	transport
FYB61_RS18775	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FYB61_RS18780	COG3842	ATPase activity
FYB61_RS18785	COG0395	ABC-type sugar transport system, permease component
FYB61_RS18810	COG2186	Transcriptional regulator
FYB61_RS18830	COG1454	alcohol dehydrogenase
FYB61_RS18845	COG2011	ABC-type metal ion transport system permease component
FYB61_RS18850	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FYB61_RS18855	COG1501	Belongs to the glycosyl hydrolase 31 family
FYB61_RS18870	COG0318	PFAM AMP-dependent synthetase and ligase
FYB61_RS18875	COG1473	amidohydrolase
FYB61_RS18885	COG2855	membrane
FYB61_RS18895	COG2239	Acts as a magnesium transporter
FYB61_RS18910	COG1522	sequence-specific DNA binding
FYB61_RS18915	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FYB61_RS18920	COG1028	Short-chain dehydrogenase reductase Sdr
FYB61_RS18945	COG0739	heme binding
FYB61_RS18955	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FYB61_RS18960	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FYB61_RS18970	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FYB61_RS19000	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FYB61_RS19005	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FYB61_RS19015	COG3116	cell division
FYB61_RS19020	COG0275	rRNA processing
FYB61_RS19025	COG2001	Belongs to the MraZ family
FYB61_RS19040	COG0418	dihydroorotase activity
FYB61_RS19045	COG1473	amidohydrolase
FYB61_RS19095	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FYB61_RS19100	COG4654	Cytochrome c, class I
FYB61_RS19155	COG2084	Dehydrogenase
FYB61_RS19200	COG0824	Thioesterase
FYB61_RS19205	COG0811	peptide transport
FYB61_RS19210	COG0848	biopolymer transport protein
FYB61_RS19235	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FYB61_RS19240	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FYB61_RS19245	COG3181	Tripartite tricarboxylate transporter family receptor
FYB61_RS19260	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FYB61_RS19285	COG0183	Belongs to the thiolase family
FYB61_RS19295	COG1960	acyl-CoA dehydrogenase activity
FYB61_RS19300	COG0583	DNA-binding transcription factor activity
FYB61_RS19305	COG3181	Tripartite tricarboxylate transporter family receptor
FYB61_RS19310	COG1024	Enoyl-CoA hydratase
FYB61_RS19315	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYB61_RS19320	COG1253	flavin adenine dinucleotide binding
FYB61_RS19325	COG1285	pathogenesis
FYB61_RS19350	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FYB61_RS19355	COG0697	spore germination
FYB61_RS19365	COG1073	alpha beta
FYB61_RS19390	COG0463	Glycosyl transferase, family 2
FYB61_RS19400	COG0786	glutamate:sodium symporter activity
FYB61_RS19410	COG2031	fatty acid transporter
FYB61_RS19425	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FYB61_RS19430	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FYB61_RS19440	COG0328	RNA-DNA hybrid ribonuclease activity
FYB61_RS19445	COG2226	methyltransferase
FYB61_RS19450	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FYB61_RS19455	COG0741	lytic transglycosylase activity
FYB61_RS19455	COG1388	LysM domain
FYB61_RS19470	COG2979	Protein of unknown function (DUF533)
FYB61_RS19490	COG3181	Tripartite tricarboxylate transporter family receptor
FYB61_RS19505	COG3119	arylsulfatase activity
FYB61_RS19530	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FYB61_RS19550	COG0832	Belongs to the urease beta subunit family
FYB61_RS19560	COG0831	urea catabolic process
FYB61_RS19565	COG0829	nickel cation binding
FYB61_RS19580	COG0633	Ferredoxin
FYB61_RS19595	COG2188	Transcriptional regulator
FYB61_RS19600	COG3799	methylaspartate ammonia-lyase activity
FYB61_RS19620	COG2719	SpoVR family
FYB61_RS19625	COG2718	Belongs to the UPF0229 family
FYB61_RS19630	COG2766	serine protein kinase
FYB61_RS19635	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FYB61_RS19635	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FYB61_RS19645	COG4977	sequence-specific DNA binding
FYB61_RS19650	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FYB61_RS19680	COG0316	Belongs to the HesB IscA family
FYB61_RS19700	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FYB61_RS19705	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FYB61_RS19710	COG0312	modulator of DNA gyrase
FYB61_RS19730	COG1116	anion transmembrane transporter activity
FYB61_RS19735	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FYB61_RS19740	COG1335	isochorismatase
FYB61_RS19745	COG0346	lactoylglutathione lyase activity
FYB61_RS19750	COG0513	Belongs to the DEAD box helicase family
FYB61_RS19760	COG1802	Transcriptional regulator
FYB61_RS19765	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FYB61_RS19765	COG1042	CoA-binding domain protein
FYB61_RS19765	COG0045	succinate-CoA ligase (ADP-forming) activity
FYB61_RS19785	COG1522	sequence-specific DNA binding
FYB61_RS19815	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FYB61_RS19820	COG1696	Membrane protein involved in D-alanine export
FYB61_RS19840	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FYB61_RS19855	COG0439	Biotin carboxylase
FYB61_RS19860	COG0511	ligase activity, forming carbon-carbon bonds
FYB61_RS19865	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FYB61_RS19870	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FYB61_RS19875	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FYB61_RS19880	COG3150	esterase
FYB61_RS19885	COG0557	exoribonuclease II activity
FYB61_RS19900	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FYB61_RS19935	COG1678	Uncharacterized ACR, COG1678
FYB61_RS19950	COG0352	thiamine-phosphate diphosphorylase activity
FYB61_RS19980	COG1960	acyl-CoA dehydrogenase activity
FYB61_RS19990	COG1028	Short-chain dehydrogenase reductase Sdr
FYB61_RS20050	COG0494	nUDIX hydrolase
FYB61_RS20075	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
FYB61_RS20100	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FYB61_RS20105	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FYB61_RS20135	COG1126	abc transporter atp-binding protein
FYB61_RS20140	COG0765	amino acid transport
FYB61_RS20145	COG4597	amino acid ABC transporter
FYB61_RS20150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYB61_RS20155	COG2884	Cell division ATP-binding protein ftsE
FYB61_RS20160	COG2177	Part of the ABC transporter FtsEX involved in
FYB61_RS20175	COG1194	a g-specific adenine glycosylase
FYB61_RS20195	COG4206	TonB-dependent receptor
FYB61_RS20200	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FYB61_RS20210	COG0351	phosphomethylpyrimidine kinase
FYB61_RS20215	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FYB61_RS20225	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FYB61_RS20235	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FYB61_RS20250	COG2226	methyltransferase
FYB61_RS20255	COG0745	RESPONSE REGULATOR receiver
FYB61_RS20260	COG5002	protein histidine kinase activity
FYB61_RS20270	COG5002	protein histidine kinase activity
FYB61_RS20280	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FYB61_RS20285	COG0583	DNA-binding transcription factor activity
FYB61_RS20295	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FYB61_RS20300	COG1984	allophanate hydrolase subunit 2
FYB61_RS20315	COG3181	Tripartite tricarboxylate transporter family receptor
FYB61_RS20325	COG1024	Enoyl-CoA hydratase
FYB61_RS20340	COG1802	Transcriptional regulator
FYB61_RS20350	COG1238	metal cluster binding
FYB61_RS20355	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FYB61_RS20360	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FYB61_RS20380	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FYB61_RS20385	COG4988	ABC transporter
FYB61_RS20395	COG1294	oxidase, subunit
FYB61_RS20420	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FYB61_RS20435	COG1137	ATPase activity
FYB61_RS20440	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FYB61_RS20455	COG2010	Cytochrome c
FYB61_RS20455	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FYB61_RS20465	COG1660	Displays ATPase and GTPase activities
FYB61_RS20475	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FYB61_RS20490	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FYB61_RS20495	COG2823	Periplasmic or secreted lipoprotein
FYB61_RS20525	COG0471	metal ion transport
FYB61_RS20530	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FYB61_RS20535	COG0772	Belongs to the SEDS family
FYB61_RS20540	COG0768	penicillin binding
FYB61_RS20550	COG1792	Involved in formation and maintenance of cell shape
FYB61_RS20555	COG1077	Cell shape determining protein MreB Mrl
FYB61_RS20580	COG0708	Exodeoxyribonuclease III
FYB61_RS20590	COG2860	membrane
FYB61_RS20600	COG0583	DNA-binding transcription factor activity
FYB61_RS20605	COG0473	3-isopropylmalate dehydrogenase activity
FYB61_RS20630	COG0583	DNA-binding transcription factor activity
FYB61_RS20635	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FYB61_RS20640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYB61_RS20645	COG0765	amino acid transport
FYB61_RS20650	COG0765	amino acid transport
FYB61_RS20655	COG1126	abc transporter atp-binding protein
FYB61_RS20660	COG1794	racemase activity, acting on amino acids and derivatives
FYB61_RS20665	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FYB61_RS20670	COG2223	nitrite transmembrane transporter activity
FYB61_RS20675	COG2813	Specifically methylates the guanine in position
FYB61_RS20675	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FYB61_RS20685	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FYB61_RS20730	COG0583	DNA-binding transcription factor activity
FYB61_RS20735	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FYB61_RS20740	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FYB61_RS20775	COG0154	amidase activity
FYB61_RS20785	COG1414	Transcriptional regulator
FYB61_RS20795	COG1250	3-hydroxyacyl-CoA dehydrogenase
FYB61_RS20795	COG1024	Enoyl-CoA hydratase
FYB61_RS20805	COG2132	Multicopper oxidase
FYB61_RS20850	COG1024	Enoyl-CoA hydratase
FYB61_RS20855	COG1024	Enoyl-CoA hydratase
FYB61_RS20860	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FYB61_RS20870	COG0747	negative chemotaxis
FYB61_RS20880	COG0601	transmembrane transport
FYB61_RS20885	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FYB61_RS20890	COG0444	Belongs to the ABC transporter superfamily
FYB61_RS20895	COG4608	Belongs to the ABC transporter superfamily
FYB61_RS20905	COG2195	Cleaves the N-terminal amino acid of tripeptides
FYB61_RS20910	COG0210	DNA helicase
FYB61_RS20915	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FYB61_RS20930	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FYB61_RS20950	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FYB61_RS20965	COG0356	it plays a direct role in the translocation of protons across the membrane
FYB61_RS20980	COG1024	Enoyl-CoA hydratase
FYB61_RS21005	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FYB61_RS21015	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FYB61_RS21020	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FYB61_RS21025	COG2967	ApaG domain
FYB61_RS21030	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FYB61_RS21035	COG0546	phosphoglycolate phosphatase activity
FYB61_RS21045	COG0512	Glutamine amidotransferase of anthranilate synthase
FYB61_RS21065	COG1028	Short-chain dehydrogenase reductase Sdr
FYB61_RS21085	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FYB61_RS21095	COG1607	acyl-coa hydrolase
FYB61_RS21150	COG1802	Transcriptional regulator
FYB61_RS21180	COG1595	DNA-templated transcription, initiation
FYB61_RS21195	COG3720	iron ion transport
FYB61_RS21200	COG4558	Periplasmic binding protein
FYB61_RS21205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FYB61_RS21215	COG1683	Conserved Protein
FYB61_RS21245	COG3064	Membrane
FYB61_RS21250	COG0583	DNA-binding transcription factor activity
FYB61_RS21260	COG1234	tRNA 3'-trailer cleavage
FYB61_RS21270	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FYB61_RS21275	COG1802	Transcriptional regulator
FYB61_RS21285	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FYB61_RS21305	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYB61_RS21325	COG3181	Tripartite tricarboxylate transporter family receptor
FYB61_RS21330	COG0583	DNA-binding transcription factor activity
FYB61_RS21340	COG1522	sequence-specific DNA binding
FYB61_RS21345	COG0183	Belongs to the thiolase family
FYB61_RS21405	COG2814	Major facilitator Superfamily
FYB61_RS21430	COG1999	signal sequence binding
FYB61_RS21470	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FYB61_RS21490	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FYB61_RS21500	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FYB61_RS21510	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FYB61_RS21515	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FYB61_RS21525	COG0069	glutamate synthase activity
FYB61_RS21525	COG0070	glutamate synthase
FYB61_RS21525	COG0067	glutamate synthase
FYB61_RS21535	COG3047	cAMP biosynthetic process
FYB61_RS21545	COG1127	ABC transporter
FYB61_RS21550	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FYB61_RS21555	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FYB61_RS21560	COG2853	Lipoprotein
FYB61_RS21570	COG1131	(ABC) transporter
FYB61_RS21575	COG0842	Transport permease protein
FYB61_RS21595	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FYB61_RS21605	COG0131	Imidazoleglycerol-phosphate dehydratase
FYB61_RS21615	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FYB61_RS21630	COG0140	phosphoribosyl-ATP diphosphatase activity
FYB61_RS21635	COG0537	adenosine 5'-monophosphoramidase activity
FYB61_RS21640	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FYB61_RS21665	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FYB61_RS21675	COG0723	plastoquinol--plastocyanin reductase activity
FYB61_RS21680	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FYB61_RS21685	COG2857	Cytochrome c1
FYB61_RS21690	COG0625	glutathione transferase activity
FYB61_RS21695	COG2969	positive regulation of protein catabolic process
FYB61_RS21725	COG0583	DNA-binding transcription factor activity
FYB61_RS21730	COG0492	ferredoxin-NADP+ reductase activity
FYB61_RS21750	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYB61_RS21760	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYB61_RS21780	COG3181	Tripartite tricarboxylate transporter family receptor
FYB61_RS21815	COG3702	type iv secretory pathway
FYB61_RS21835	COG3736	Type IV secretory pathway, component VirB8
FYB61_RS21850	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
FYB61_RS21860	COG0697	spore germination
FYB61_RS21880	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FYB61_RS21885	COG0747	negative chemotaxis
FYB61_RS21895	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FYB61_RS21905	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
FYB61_RS21915	COG0513	Belongs to the DEAD box helicase family
FYB61_RS21920	COG1280	lysine exporter protein (LysE YggA)
FYB61_RS21945	COG0583	DNA-binding transcription factor activity
FYB61_RS21955	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FYB61_RS21965	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FYB61_RS21970	COG0154	amidase activity
FYB61_RS21975	COG1609	Transcriptional regulator
FYB61_RS21995	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FYB61_RS22000	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FYB61_RS22005	COG3842	ATPase activity
FYB61_RS22010	COG1653	transport
FYB61_RS22015	COG1175	transmembrane transport
FYB61_RS22020	COG0395	ABC-type sugar transport system, permease component
FYB61_RS22055	COG1280	lysine exporter protein (LysE YggA)
FYB61_RS22070	COG1960	acyl-CoA dehydrogenase activity
FYB61_RS22080	COG0183	Belongs to the thiolase family
FYB61_RS22085	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FYB61_RS22105	COG3181	Tripartite tricarboxylate transporter family receptor
FYB61_RS22115	COG2358	TRAP transporter, solute receptor (TAXI family
FYB61_RS22130	COG2922	Belongs to the Smg family
FYB61_RS22155	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FYB61_RS22160	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FYB61_RS22165	COG1028	Short-chain dehydrogenase reductase Sdr
FYB61_RS22170	COG1012	belongs to the aldehyde dehydrogenase family
FYB61_RS22180	COG0028	Belongs to the TPP enzyme family
FYB61_RS22185	COG1522	sequence-specific DNA binding
FYB61_RS22190	COG3781	membrane
FYB61_RS22220	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FYB61_RS22245	COG1304	FMN binding
FYB61_RS22265	COG1414	Transcriptional regulator
FYB61_RS22280	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FYB61_RS22285	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FYB61_RS22290	COG0594	ribonuclease P activity
FYB61_RS22295	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FYB61_RS22305	COG0753	catalase activity
FYB61_RS22310	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FYB61_RS22315	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FYB61_RS22325	COG2175	clavaminate synthase activity
FYB61_RS22330	COG1473	amidohydrolase
FYB61_RS22335	COG4608	Belongs to the ABC transporter superfamily
FYB61_RS22340	COG0444	Belongs to the ABC transporter superfamily
FYB61_RS22350	COG0601	transmembrane transport
FYB61_RS22355	COG0747	negative chemotaxis
FYB61_RS22375	COG5002	protein histidine kinase activity
FYB61_RS22375	COG3850	Histidine kinase
FYB61_RS22395	COG0436	Aminotransferase
FYB61_RS22400	COG1278	Cold shock
