locus-tag	class	description
BH370_RS00005	COG0445	tRNA wobble uridine modification
BH370_RS00010	COG0357	Ribosomal RNA small subunit methyltransferase G
BH370_RS00015	COG1192	Involved in chromosome partitioning
BH370_RS00025	COG1475	DNA binding
BH370_RS00030	COG0252	asparaginase activity
BH370_RS00055	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BH370_RS00065	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BH370_RS00075	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BH370_RS00080	COG0081	regulation of translation
BH370_RS00085	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BH370_RS00090	COG0222	ribosome binding
BH370_RS00095	COG0085	RNA polymerase activity
BH370_RS00100	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BH370_RS00140	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH370_RS00165	COG1024	Enoyl-CoA hydratase
BH370_RS00190	COG0752	glycyl-tRNA synthetase alpha subunit
BH370_RS00195	COG0751	glycine-tRNA ligase activity
BH370_RS00200	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BH370_RS00205	COG0204	Acyl-transferase
BH370_RS00220	COG0242	peptide deformylase activity
BH370_RS00265	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BH370_RS00270	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BH370_RS00270	COG2813	Specifically methylates the guanine in position
BH370_RS00280	COG2223	nitrite transmembrane transporter activity
BH370_RS00290	COG1794	racemase activity, acting on amino acids and derivatives
BH370_RS00295	COG1126	abc transporter atp-binding protein
BH370_RS00300	COG0765	amino acid transport
BH370_RS00305	COG0765	amino acid transport
BH370_RS00310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BH370_RS00370	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BH370_RS00400	COG0326	Molecular chaperone. Has ATPase activity
BH370_RS00405	COG0625	glutathione transferase activity
BH370_RS00420	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BH370_RS00425	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BH370_RS00455	COG0438	transferase activity, transferring glycosyl groups
BH370_RS00460	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BH370_RS00465	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BH370_RS00495	COG0859	PFAM glycosyl transferase family 9
BH370_RS00510	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BH370_RS00520	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BH370_RS00525	COG1127	ABC transporter
BH370_RS00550	COG1686	Belongs to the peptidase S11 family
BH370_RS00560	COG2921	Belongs to the UPF0250 family
BH370_RS00565	COG0321	lipoyl(octanoyl) transferase activity
BH370_RS00570	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BH370_RS00605	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BH370_RS00615	COG0018	arginyl-trna synthetase
BH370_RS00635	COG0395	ABC-type sugar transport system, permease component
BH370_RS00640	COG1175	transmembrane transport
BH370_RS00645	COG1653	transport
BH370_RS00650	COG3842	ATPase activity
BH370_RS00655	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BH370_RS00665	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BH370_RS00685	COG1609	Transcriptional regulator
BH370_RS00695	COG0154	amidase activity
BH370_RS00700	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BH370_RS00710	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BH370_RS00720	COG0583	DNA-binding transcription factor activity
BH370_RS00740	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BH370_RS00755	COG1802	Transcriptional regulator
BH370_RS00770	COG1024	Enoyl-CoA hydratase
BH370_RS00785	COG3181	Tripartite tricarboxylate transporter family receptor
BH370_RS00800	COG1984	allophanate hydrolase subunit 2
BH370_RS00805	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BH370_RS00815	COG0583	DNA-binding transcription factor activity
BH370_RS00820	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BH370_RS00830	COG5002	protein histidine kinase activity
BH370_RS00840	COG5002	protein histidine kinase activity
BH370_RS00845	COG0745	RESPONSE REGULATOR receiver
BH370_RS00850	COG2226	methyltransferase
BH370_RS00865	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BH370_RS00885	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BH370_RS00895	COG0513	Belongs to the DEAD box helicase family
BH370_RS00900	COG1280	lysine exporter protein (LysE YggA)
BH370_RS00905	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BH370_RS00945	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BH370_RS00945	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BH370_RS00955	COG0489	protein tyrosine kinase activity
BH370_RS00970	COG0717	Belongs to the dCTP deaminase family
BH370_RS00995	COG1982	Orn Lys Arg decarboxylase major
BH370_RS01000	COG2081	HI0933 family
BH370_RS01010	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BH370_RS01020	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BH370_RS01025	COG0509	glycine decarboxylation via glycine cleavage system
BH370_RS01030	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BH370_RS01030	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BH370_RS01070	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BH370_RS01085	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BH370_RS01095	COG1414	Transcriptional regulator
BH370_RS01100	COG1028	Short-chain dehydrogenase reductase Sdr
BH370_RS01105	COG2031	fatty acid transporter
BH370_RS01110	COG1250	3-hydroxyacyl-CoA dehydrogenase
BH370_RS01120	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BH370_RS01125	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BH370_RS01135	COG4257	antibiotic catabolic process
BH370_RS01155	COG1012	belongs to the aldehyde dehydrogenase family
BH370_RS01160	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BH370_RS01165	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BH370_RS01190	COG1028	Short-chain dehydrogenase reductase Sdr
BH370_RS01200	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BH370_RS01210	COG2188	Transcriptional regulator
BH370_RS01215	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BH370_RS01240	COG0617	tRNA 3'-terminal CCA addition
BH370_RS01255	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BH370_RS01260	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BH370_RS01265	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BH370_RS01270	COG0586	Pfam SNARE associated Golgi protein
BH370_RS01275	COG0860	N-Acetylmuramoyl-L-alanine amidase
BH370_RS01280	COG0802	atpase or kinase
BH370_RS01285	COG0114	fumarate hydratase activity
BH370_RS01295	COG3181	Tripartite tricarboxylate transporter family receptor
BH370_RS01305	COG0405	Gamma-glutamyltransferase
BH370_RS01310	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH370_RS01345	COG1294	oxidase, subunit
BH370_RS01355	COG4988	ABC transporter
BH370_RS01360	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BH370_RS01365	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BH370_RS01405	COG2969	positive regulation of protein catabolic process
BH370_RS01410	COG0625	glutathione transferase activity
BH370_RS01415	COG2857	Cytochrome c1
BH370_RS01420	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BH370_RS01425	COG0723	plastoquinol--plastocyanin reductase activity
BH370_RS01430	COG1970	mechanosensitive ion channel activity
BH370_RS01435	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BH370_RS01450	COG2808	Putative FMN-binding domain
BH370_RS01455	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BH370_RS01460	COG0747	negative chemotaxis
BH370_RS01465	COG0657	acetylesterase activity
BH370_RS01475	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BH370_RS01480	COG2207	Transcriptional regulator
BH370_RS01485	COG0129	dihydroxy-acid dehydratase activity
BH370_RS01490	COG2814	Major facilitator Superfamily
BH370_RS01495	COG0583	DNA-binding transcription factor activity
BH370_RS01505	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
BH370_RS01575	COG1024	Enoyl-CoA hydratase
BH370_RS01580	COG1960	acyl-CoA dehydrogenase activity
BH370_RS01605	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BH370_RS01610	COG0352	thiamine-phosphate diphosphorylase activity
BH370_RS01625	COG1678	Uncharacterized ACR, COG1678
BH370_RS01630	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BH370_RS01635	COG0540	Belongs to the ATCase OTCase family
BH370_RS01650	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BH370_RS01660	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BH370_RS01695	COG1234	tRNA 3'-trailer cleavage
BH370_RS01710	COG3064	Membrane
BH370_RS01740	COG1683	Conserved Protein
BH370_RS01745	COG1120	ATPase activity
BH370_RS01750	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BH370_RS01755	COG4558	Periplasmic binding protein
BH370_RS01760	COG3720	iron ion transport
BH370_RS01770	COG3712	iron ion homeostasis
BH370_RS01775	COG1595	DNA-templated transcription, initiation
BH370_RS01810	COG1802	Transcriptional regulator
BH370_RS01820	COG3069	C4-dicarboxylate transmembrane transporter activity
BH370_RS01830	COG1012	belongs to the aldehyde dehydrogenase family
BH370_RS01865	COG2860	membrane
BH370_RS01870	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BH370_RS01875	COG0708	Exodeoxyribonuclease III
BH370_RS01880	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BH370_RS01885	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BH370_RS01890	COG0154	amidase activity
BH370_RS01895	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BH370_RS01900	COG1077	Cell shape determining protein MreB Mrl
BH370_RS01905	COG1792	Involved in formation and maintenance of cell shape
BH370_RS01915	COG0768	penicillin binding
BH370_RS01920	COG0772	Belongs to the SEDS family
BH370_RS01925	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BH370_RS01930	COG0471	metal ion transport
BH370_RS01935	COG1309	transcriptional regulator
BH370_RS01945	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BH370_RS01960	COG2823	Periplasmic or secreted lipoprotein
BH370_RS01965	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BH370_RS01980	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BH370_RS02000	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH370_RS02010	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH370_RS02035	COG0492	ferredoxin-NADP+ reductase activity
BH370_RS02045	COG3181	Tripartite tricarboxylate transporter family receptor
BH370_RS02050	COG1024	Enoyl-CoA hydratase
BH370_RS02050	COG1250	3-hydroxyacyl-CoA dehydrogenase
BH370_RS02055	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH370_RS02060	COG0028	Belongs to the TPP enzyme family
BH370_RS02085	COG3181	Tripartite tricarboxylate transporter family receptor
BH370_RS02095	COG0697	spore germination
BH370_RS02120	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BH370_RS02125	COG0463	Glycosyl transferase, family 2
BH370_RS02140	COG0786	glutamate:sodium symporter activity
BH370_RS02150	COG2031	fatty acid transporter
BH370_RS02165	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BH370_RS02180	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BH370_RS02195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BH370_RS02205	COG1285	pathogenesis
BH370_RS02210	COG1253	flavin adenine dinucleotide binding
BH370_RS02215	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH370_RS02220	COG1024	Enoyl-CoA hydratase
BH370_RS02225	COG3181	Tripartite tricarboxylate transporter family receptor
BH370_RS02230	COG0583	DNA-binding transcription factor activity
BH370_RS02235	COG1960	acyl-CoA dehydrogenase activity
BH370_RS02245	COG0183	Belongs to the thiolase family
BH370_RS02265	COG0583	DNA-binding transcription factor activity
BH370_RS02270	COG1278	Cold shock
BH370_RS02280	COG1802	Transcriptional regulator
BH370_RS02285	COG1012	belongs to the aldehyde dehydrogenase family
BH370_RS02290	COG2031	fatty acid transporter
BH370_RS02295	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BH370_RS02295	COG1017	nitric oxide dioxygenase activity
BH370_RS02300	COG0251	oxidation-reduction process
BH370_RS02325	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH370_RS02335	COG0583	DNA-binding transcription factor activity
BH370_RS02340	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH370_RS02350	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
BH370_RS02355	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BH370_RS02360	COG0546	phosphoglycolate phosphatase activity
BH370_RS02370	COG1530	ribonuclease E activity
BH370_RS02390	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BH370_RS02395	COG0159	tryptophan synthase activity
BH370_RS02400	COG0133	tryptophan synthase activity
BH370_RS02410	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BH370_RS02415	COG3228	Belongs to the MtfA family
BH370_RS02425	COG0251	oxidation-reduction process
BH370_RS02430	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BH370_RS02435	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BH370_RS02450	COG2878	Part of a membrane complex involved in electron transport
BH370_RS02455	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BH370_RS02490	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BH370_RS02510	COG1268	BioY protein
BH370_RS02515	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BH370_RS02520	COG1122	ATPase activity
BH370_RS02525	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BH370_RS02540	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BH370_RS02545	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BH370_RS02555	COG1196	nuclear chromosome segregation
BH370_RS02560	COG0477	Major facilitator Superfamily
BH370_RS02565	COG1573	uracil-dna glycosylase
BH370_RS02570	COG1214	PFAM Peptidase M22, glycoprotease
BH370_RS02575	COG0745	RESPONSE REGULATOR receiver
BH370_RS02590	COG0450	alkyl hydroperoxide reductase
BH370_RS02595	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BH370_RS02605	COG2223	nitrite transmembrane transporter activity
BH370_RS02615	COG2186	Transcriptional regulator
BH370_RS02635	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BH370_RS02645	COG0583	DNA-binding transcription factor activity
BH370_RS02655	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BH370_RS02660	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BH370_RS02665	COG0137	argininosuccinate synthase activity
BH370_RS02670	COG3158	transport of potassium into the cell
BH370_RS02675	COG0642	Histidine kinase
BH370_RS02705	COG0776	regulation of translation
BH370_RS02710	COG3128	pkhd-type hydroxylase
BH370_RS02720	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BH370_RS02725	COG0557	exoribonuclease II activity
BH370_RS02750	COG0679	Auxin Efflux Carrier
BH370_RS02755	COG2391	methyltransferase activity
BH370_RS02760	COG0069	glutamate synthase activity
BH370_RS02770	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BH370_RS02780	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
BH370_RS02820	COG3706	GGDEF domain
BH370_RS02840	COG0583	DNA-binding transcription factor activity
BH370_RS02850	COG1053	succinate dehydrogenase
BH370_RS02870	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BH370_RS02875	COG0459	protein refolding
BH370_RS02880	COG3468	outer membrane autotransporter barrel domain protein
BH370_RS02895	COG1252	NADH dehydrogenase
BH370_RS02900	COG0284	orotidine-5'-phosphate decarboxylase activity
BH370_RS02905	COG1058	Belongs to the CinA family
BH370_RS02905	COG1546	Belongs to the CinA family
BH370_RS02910	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BH370_RS02920	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BH370_RS02925	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BH370_RS02965	COG3639	organic phosphonate transmembrane transporter activity
BH370_RS02970	COG3639	organic phosphonate transmembrane transporter activity
BH370_RS02990	COG0742	ribosomal rna small subunit methyltransferase
BH370_RS02995	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BH370_RS03000	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BH370_RS03005	COG3135	benzoate transporter
BH370_RS03020	COG0640	Transcriptional regulator
BH370_RS03050	COG4172	Belongs to the ABC transporter superfamily
BH370_RS03055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BH370_RS03060	COG0601	transmembrane transport
BH370_RS03070	COG0281	malic enzyme
BH370_RS03070	COG0280	phosphate acetyltransferase
BH370_RS03130	COG0583	DNA-binding transcription factor activity
BH370_RS03140	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BH370_RS03145	COG0167	dihydroorotate dehydrogenase activity
BH370_RS03165	COG1414	Transcriptional regulator
BH370_RS03170	COG1058	Belongs to the CinA family
BH370_RS03170	COG1546	Belongs to the CinA family
BH370_RS03190	COG0513	Belongs to the DEAD box helicase family
BH370_RS03220	COG0429	hydrolase of the alpha beta-hydrolase fold
BH370_RS03225	COG4783	chaperone-mediated protein folding
BH370_RS03240	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BH370_RS03265	COG0006	proline dipeptidase activity
BH370_RS03275	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BH370_RS03295	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BH370_RS03300	COG0632	four-way junction helicase activity
BH370_RS03315	COG2255	four-way junction helicase activity
BH370_RS03320	COG0514	ATP-dependent DNA helicase (RecQ)
BH370_RS03335	COG0288	reversible hydration of carbon dioxide
BH370_RS03340	COG0154	amidase activity
BH370_RS03350	COG4211	Belongs to the binding-protein-dependent transport system permease family
BH370_RS03380	COG1464	Belongs to the NlpA lipoprotein family
BH370_RS03525	COG1196	nuclear chromosome segregation
BH370_RS03590	COG2135	peptidase activity
BH370_RS03605	COG0494	nUDIX hydrolase
BH370_RS03610	COG0442	prolyl-tRNA aminoacylation
BH370_RS03615	COG0824	Thioesterase
BH370_RS03620	COG0811	peptide transport
BH370_RS03625	COG0848	biopolymer transport protein
BH370_RS03635	COG0823	Involved in the tonB-independent uptake of proteins
BH370_RS03650	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BH370_RS03655	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BH370_RS03685	COG0700	Nucleoside recognition
BH370_RS03690	COG0469	pyruvate kinase activity
BH370_RS03695	COG1929	Belongs to the glycerate kinase type-1 family
BH370_RS03700	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BH370_RS03705	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BH370_RS03710	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BH370_RS03720	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BH370_RS03730	COG2154	pterin-4-alpha-carbinolamine dehydratase
BH370_RS03755	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BH370_RS03760	COG0154	amidase activity
BH370_RS03770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BH370_RS03775	COG0601	transmembrane transport
BH370_RS03780	COG0747	negative chemotaxis
BH370_RS03800	COG0019	diaminopimelate decarboxylase activity
BH370_RS03820	COG2353	YceI-like domain
BH370_RS03825	COG4774	siderophore transport
BH370_RS03830	COG3712	iron ion homeostasis
BH370_RS03870	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BH370_RS03875	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BH370_RS03880	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BH370_RS03885	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BH370_RS03895	COG0142	geranyltranstransferase activity
BH370_RS03905	COG0583	DNA-binding transcription factor activity
BH370_RS03915	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
BH370_RS03920	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BH370_RS03935	COG2994	toxin metabolic process
BH370_RS03945	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
BH370_RS03950	COG2274	protein secretion by the type I secretion system
BH370_RS03955	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BH370_RS03960	COG1538	Outer membrane efflux protein
BH370_RS03980	COG0765	amino acid transport
BH370_RS03985	COG1126	abc transporter atp-binding protein
BH370_RS04005	COG1028	Short-chain dehydrogenase reductase Sdr
BH370_RS04015	COG1802	Transcriptional regulator
BH370_RS04025	COG1802	Transcriptional regulator
BH370_RS04035	COG0318	PFAM AMP-dependent synthetase and ligase
BH370_RS04045	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BH370_RS04065	COG0028	Belongs to the TPP enzyme family
BH370_RS04085	COG0308	aminopeptidase N
BH370_RS04090	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BH370_RS04100	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BH370_RS04105	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BH370_RS04110	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BH370_RS04115	COG0560	Phosphoserine phosphatase
BH370_RS04120	COG0583	DNA-binding transcription factor activity
BH370_RS04125	COG3181	Tripartite tricarboxylate transporter family receptor
BH370_RS04130	COG0028	Belongs to the TPP enzyme family
BH370_RS04145	COG4774	siderophore transport
BH370_RS04150	COG4774	siderophore transport
BH370_RS04160	COG1007	ATP synthesis coupled electron transport
BH370_RS04175	COG0713	ATP synthesis coupled electron transport
BH370_RS04185	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BH370_RS04190	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BH370_RS04195	COG1034	ATP synthesis coupled electron transport
BH370_RS04205	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BH370_RS04210	COG0649	NAD binding
BH370_RS04215	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BH370_RS04220	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BH370_RS04225	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BH370_RS04230	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BH370_RS04255	COG0671	phosphoesterase, PA-phosphatase related
BH370_RS04265	COG1597	lipid kinase activity
BH370_RS04270	COG0583	DNA-binding transcription factor activity
BH370_RS04275	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BH370_RS04285	COG1733	regulation of RNA biosynthetic process
BH370_RS04290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BH370_RS04295	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BH370_RS04310	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
BH370_RS04330	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BH370_RS04350	COG3608	succinylglutamate desuccinylase aspartoacylase
BH370_RS04355	COG0626	cystathionine gamma-synthase activity
BH370_RS04360	COG0583	DNA-binding transcription factor activity
BH370_RS04400	COG3799	methylaspartate ammonia-lyase activity
BH370_RS04410	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BH370_RS04420	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BH370_RS04425	COG0149	triose-phosphate isomerase activity
BH370_RS04445	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BH370_RS04460	COG1185	polyribonucleotide nucleotidyltransferase activity
BH370_RS04465	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BH370_RS04475	COG1183	phosphatidylcholine synthase activity
BH370_RS04480	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BH370_RS04485	COG0440	acetolactate synthase activity
BH370_RS04490	COG0028	Belongs to the TPP enzyme family
BH370_RS04505	COG5265	(ABC) transporter
BH370_RS04510	COG0500	methyltransferase
BH370_RS04525	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
BH370_RS04555	COG0511	ligase activity, forming carbon-carbon bonds
BH370_RS04580	COG2188	Transcriptional regulator
BH370_RS04585	COG0439	Biotin carboxylase
BH370_RS04635	COG5265	(ABC) transporter
BH370_RS04645	COG0667	Aldo Keto reductase
BH370_RS04660	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BH370_RS04695	COG0583	DNA-binding transcription factor activity
BH370_RS04720	COG2814	Major facilitator Superfamily
BH370_RS04730	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BH370_RS04745	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BH370_RS04755	COG0287	Prephenate dehydrogenase
BH370_RS04760	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BH370_RS04765	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BH370_RS04785	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BH370_RS04790	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BH370_RS04795	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BH370_RS04815	COG2951	lytic endotransglycosylase activity
BH370_RS04820	COG0123	including yeast histone deacetylase and acetoin utilization protein
BH370_RS04835	COG1960	acyl-CoA dehydrogenase activity
BH370_RS04840	COG0450	alkyl hydroperoxide reductase
BH370_RS04865	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BH370_RS04900	COG0335	large ribosomal subunit rRNA binding
BH370_RS04910	COG0667	Aldo Keto reductase
BH370_RS04925	COG3161	chorismate lyase activity
BH370_RS04930	COG1187	pseudouridine synthase activity
BH370_RS04960	COG1999	signal sequence binding
BH370_RS04965	COG0339	signal peptide processing
BH370_RS04970	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BH370_RS04975	COG4566	intracellular signal transduction
BH370_RS04985	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BH370_RS04990	COG0508	dehydrogenase complex catalyzes the overall conversion of
BH370_RS04995	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BH370_RS05000	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BH370_RS05010	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BH370_RS05015	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BH370_RS05020	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BH370_RS05025	COG0126	phosphoglycerate kinase activity
BH370_RS05030	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BH370_RS05035	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BH370_RS05050	COG0625	glutathione transferase activity
BH370_RS05080	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BH370_RS05085	COG0306	phosphate transporter
BH370_RS05090	COG0521	Mo-molybdopterin cofactor biosynthetic process
BH370_RS05100	COG0739	heme binding
BH370_RS05110	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BH370_RS05145	COG0745	RESPONSE REGULATOR receiver
BH370_RS05160	COG0840	transmembrane signaling receptor activity
BH370_RS05170	COG2201	protein-glutamate methylesterase activity
BH370_RS05175	COG0745	RESPONSE REGULATOR receiver
BH370_RS05180	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
BH370_RS05205	COG0667	Aldo Keto reductase
BH370_RS05215	COG4535	Mg2 and Co2 transporter CorC
BH370_RS05220	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BH370_RS05225	COG1702	phosphate starvation-inducible protein PhoH
BH370_RS05230	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BH370_RS05245	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BH370_RS05250	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BH370_RS05255	COG1862	Preprotein translocase
BH370_RS05260	COG0343	queuine tRNA-ribosyltransferase activity
BH370_RS05265	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BH370_RS05270	COG2027	D-alanyl-D-alanine carboxypeptidase
BH370_RS05275	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BH370_RS05285	COG3468	outer membrane autotransporter barrel domain protein
BH370_RS05290	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BH370_RS05290	COG1648	precorrin-2 dehydrogenase activity
BH370_RS05315	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BH370_RS05320	COG0741	lytic transglycosylase activity
BH370_RS05325	COG0436	Aminotransferase
BH370_RS05335	COG0281	malic enzyme
BH370_RS05335	COG0280	phosphate acetyltransferase
BH370_RS05345	COG2732	(Barnase) inhibitor
BH370_RS05365	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BH370_RS05390	COG0248	Ppx GppA phosphatase
BH370_RS05400	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BH370_RS05410	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BH370_RS05415	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BH370_RS05420	COG1534	Rna-binding protein
BH370_RS05445	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BH370_RS05460	COG1295	ribonuclease BN
BH370_RS05470	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BH370_RS05475	COG0745	RESPONSE REGULATOR receiver
BH370_RS05480	COG2205	protein histidine kinase activity
BH370_RS05515	COG1022	Amp-dependent synthetase and ligase
BH370_RS05530	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BH370_RS05535	COG1028	Short-chain dehydrogenase reductase Sdr
BH370_RS05545	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BH370_RS05560	COG1136	(ABC) transporter
BH370_RS05565	COG0084	hydrolase, TatD family'
BH370_RS05600	COG0613	PHP domain protein
BH370_RS05615	COG3539	Fimbrial protein
BH370_RS05620	COG0281	malic enzyme
BH370_RS05620	COG0280	phosphate acetyltransferase
BH370_RS05630	COG1522	sequence-specific DNA binding
BH370_RS05645	COG0567	Dehydrogenase, E1 component
BH370_RS05650	COG0508	dehydrogenase complex catalyzes the overall conversion of
BH370_RS05655	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BH370_RS05660	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BH370_RS05665	COG1028	Short-chain dehydrogenase reductase Sdr
BH370_RS05670	COG0583	DNA-binding transcription factor activity
BH370_RS05685	COG3181	Tripartite tricarboxylate transporter family receptor
BH370_RS05705	COG0180	Tryptophanyl-tRNA synthetase
BH370_RS05710	COG2183	response to ionizing radiation
BH370_RS05715	COG1199	ATP-dependent helicase activity
BH370_RS05725	COG0564	pseudouridine synthase activity
BH370_RS05735	COG3243	poly(R)-hydroxyalkanoic acid synthase
BH370_RS05740	COG1028	Short-chain dehydrogenase reductase Sdr
BH370_RS05745	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
BH370_RS05760	COG0672	)-iron permease
BH370_RS05810	COG0583	DNA-binding transcription factor activity
BH370_RS05820	COG2814	Major facilitator Superfamily
BH370_RS05835	COG1619	proteins homologs of microcin C7 resistance protein MccF
BH370_RS05850	COG2084	Dehydrogenase
BH370_RS05855	COG3181	Tripartite tricarboxylate transporter family receptor
BH370_RS05880	COG2988	succinylglutamate desuccinylase activity
BH370_RS05905	COG0765	amino acid transport
BH370_RS05910	COG0765	amino acid transport
BH370_RS05915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BH370_RS05950	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BH370_RS05955	COG1595	DNA-templated transcription, initiation
BH370_RS05965	COG3530	Putative quorum-sensing-regulated virulence factor
BH370_RS05970	COG0494	nUDIX hydrolase
BH370_RS05985	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BH370_RS05990	COG0542	response to heat
BH370_RS06005	COG3468	outer membrane autotransporter barrel domain protein
BH370_RS06015	COG5441	Belongs to the UPF0261 family
BH370_RS06020	COG5564	TIM-barrel signal transduction protein
BH370_RS06035	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BH370_RS06050	COG1477	protein flavinylation
BH370_RS06070	COG1131	(ABC) transporter
BH370_RS06075	COG0842	Transport permease protein
BH370_RS06085	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BH370_RS06090	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
BH370_RS06090	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
BH370_RS06095	COG1562	ergosterol biosynthetic process
BH370_RS06100	COG1562	ergosterol biosynthetic process
BH370_RS06105	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BH370_RS06110	COG1028	Short-chain dehydrogenase reductase Sdr
BH370_RS06130	COG2304	oxidoreductase activity
BH370_RS06150	COG0534	Mate efflux family protein
BH370_RS06160	COG0254	rRNA binding
BH370_RS06165	COG3483	tryptophan 2,3-dioxygenase activity
BH370_RS06170	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BH370_RS06175	COG2003	Belongs to the UPF0758 family
BH370_RS06180	COG1047	Peptidyl-prolyl cis-trans
BH370_RS06185	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BH370_RS06190	COG0625	glutathione transferase activity
BH370_RS06210	COG0523	cobalamin synthesis protein
BH370_RS06220	COG0583	DNA-binding transcription factor activity
BH370_RS06230	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BH370_RS06235	COG1187	pseudouridine synthase activity
BH370_RS06240	COG0779	Required for maturation of 30S ribosomal subunits
BH370_RS06245	COG2251	uridine kinase activity
BH370_RS06245	COG0195	Participates in both transcription termination and antitermination
BH370_RS06250	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BH370_RS06255	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BH370_RS06260	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BH370_RS06280	COG1611	Belongs to the LOG family
BH370_RS06295	COG0412	Dienelactone hydrolase
BH370_RS06300	COG1283	sodium-dependent phosphate transmembrane transporter activity
BH370_RS06305	COG1760	l-serine dehydratase
BH370_RS06310	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BH370_RS06315	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BH370_RS06325	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BH370_RS06350	COG2311	Membrane
BH370_RS06375	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BH370_RS06395	COG0559	Belongs to the binding-protein-dependent transport system permease family
BH370_RS06410	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BH370_RS06420	COG1653	transport
BH370_RS06425	COG1175	transmembrane transport
BH370_RS06430	COG0395	ABC-type sugar transport system, permease component
BH370_RS06435	COG3842	ATPase activity
BH370_RS06460	COG2363	Small membrane protein
BH370_RS06475	COG1464	Belongs to the NlpA lipoprotein family
BH370_RS06485	COG0688	phosphatidylethanolamine metabolic process
BH370_RS06515	COG0625	glutathione transferase activity
BH370_RS06520	COG0386	Belongs to the glutathione peroxidase family
BH370_RS06540	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH370_RS06570	COG2259	Doxx family
BH370_RS06585	COG0667	Aldo Keto reductase
BH370_RS06615	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BH370_RS06640	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BH370_RS06650	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BH370_RS06705	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BH370_RS06710	COG3568	Endonuclease Exonuclease Phosphatase
BH370_RS06715	COG1695	Transcriptional regulator
BH370_RS06735	COG0583	DNA-binding transcription factor activity
BH370_RS06750	COG1802	Transcriptional regulator
BH370_RS06760	COG3181	Tripartite tricarboxylate transporter family receptor
BH370_RS06770	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH370_RS06785	COG0066	3-isopropylmalate dehydratase activity
BH370_RS06795	COG3181	Tripartite tricarboxylate transporter family receptor
BH370_RS06800	COG4948	Mandelate Racemase Muconate Lactonizing
BH370_RS06815	COG1126	abc transporter atp-binding protein
BH370_RS06825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BH370_RS06865	COG1815	bacterial-type flagellum-dependent cell motility
BH370_RS06870	COG1558	bacterial-type flagellum-dependent cell motility
BH370_RS06880	COG1749	Flagellar hook protein flgE
BH370_RS06895	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BH370_RS06900	COG1706	bacterial-type flagellum-dependent cell motility
BH370_RS06910	COG1256	bacterial-type flagellum assembly
BH370_RS06920	COG0840	transmembrane signaling receptor activity
BH370_RS06925	COG0840	transmembrane signaling receptor activity
BH370_RS06930	COG0840	transmembrane signaling receptor activity
BH370_RS06950	COG1338	Plays a role in the flagellum-specific transport system
BH370_RS06970	COG1580	Controls the rotational direction of flagella during chemotaxis
BH370_RS06995	COG1157	protein secretion by the type III secretion system
BH370_RS07005	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BH370_RS07015	COG1677	Flagellar hook-basal body complex protein FliE
BH370_RS07025	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BH370_RS07060	COG0285	dihydrofolate synthase activity
BH370_RS07090	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BH370_RS07095	COG0024	Methionine aminopeptidase
BH370_RS07100	COG0052	Belongs to the universal ribosomal protein uS2 family
BH370_RS07105	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BH370_RS07110	COG0528	UMP kinase activity
BH370_RS07115	COG0233	cytoplasmic translational termination
BH370_RS07120	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BH370_RS07130	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BH370_RS07135	COG0750	zinc metalloprotease
BH370_RS07140	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BH370_RS07145	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
BH370_RS07150	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BH370_RS07155	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BH370_RS07165	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BH370_RS07170	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BH370_RS07175	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BH370_RS07180	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BH370_RS07190	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BH370_RS07190	COG0519	Catalyzes the synthesis of GMP from XMP
BH370_RS07205	COG0330	HflC and HflK could
BH370_RS07210	COG3706	GGDEF domain
BH370_RS07215	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BH370_RS07225	COG2867	negative regulation of translational initiation
BH370_RS07235	COG1960	acyl-CoA dehydrogenase activity
BH370_RS07240	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BH370_RS07270	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BH370_RS07275	COG0505	Belongs to the CarA family
BH370_RS07280	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BH370_RS07290	COG0406	alpha-ribazole phosphatase activity
BH370_RS07300	COG3842	ATPase activity
BH370_RS07320	COG5001	Diguanylate cyclase
BH370_RS07325	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BH370_RS07335	COG1763	Mo-molybdopterin cofactor biosynthetic process
BH370_RS07340	COG0303	'Molybdopterin
BH370_RS07345	COG0746	molybdenum cofactor guanylyltransferase activity
BH370_RS07350	COG0489	protein tyrosine kinase activity
BH370_RS07380	COG0243	molybdopterin cofactor binding
BH370_RS07380	COG3383	formate dehydrogenase (NAD+) activity
BH370_RS07415	COG1122	ATPase activity
BH370_RS07425	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BH370_RS07430	COG0066	3-isopropylmalate dehydratase activity
BH370_RS07435	COG0473	3-isopropylmalate dehydrogenase activity
BH370_RS07440	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BH370_RS07450	COG0101	tRNA pseudouridine synthase activity
BH370_RS07455	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BH370_RS07470	COG0135	phosphoribosylanthranilate isomerase activity
BH370_RS07485	COG3022	response to hydroperoxide
BH370_RS07495	COG1289	transmembrane transporter activity
BH370_RS07505	COG3706	GGDEF domain
BH370_RS07525	COG2197	response regulator
BH370_RS07530	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BH370_RS07535	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BH370_RS07540	COG0189	ligase activity
BH370_RS07550	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BH370_RS07555	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BH370_RS07565	COG2423	ornithine cyclodeaminase activity
BH370_RS07575	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BH370_RS07580	COG0765	amino acid transport
BH370_RS07585	COG0765	amino acid transport
BH370_RS07590	COG1126	abc transporter atp-binding protein
BH370_RS07645	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BH370_RS07655	COG2944	sequence-specific DNA binding
BH370_RS07660	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BH370_RS07665	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BH370_RS07670	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BH370_RS07675	COG0009	L-threonylcarbamoyladenylate synthase
BH370_RS07680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BH370_RS07685	COG1414	Transcriptional regulator
BH370_RS07700	COG0765	amino acid transport
BH370_RS07705	COG1126	abc transporter atp-binding protein
BH370_RS07710	COG0028	Belongs to the TPP enzyme family
BH370_RS07725	COG0028	Belongs to the TPP enzyme family
BH370_RS07730	COG0583	DNA-binding transcription factor activity
BH370_RS07735	COG4974	Belongs to the 'phage' integrase family
BH370_RS07740	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BH370_RS07745	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BH370_RS07760	COG1686	Belongs to the peptidase S11 family
BH370_RS07770	COG2814	Major facilitator Superfamily
BH370_RS07780	COG1074	ATP-dependent DNA helicase activity
BH370_RS07790	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BH370_RS07795	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BH370_RS07800	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BH370_RS07820	COG2321	neutral zinc metallopeptidase
BH370_RS07825	COG0009	L-threonylcarbamoyladenylate synthase
BH370_RS07865	COG3360	Dodecin
BH370_RS07870	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BH370_RS07875	COG2850	peptidyl-arginine hydroxylation
BH370_RS07880	COG3539	Fimbrial protein
BH370_RS07885	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BH370_RS07890	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BH370_RS07905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BH370_RS07910	COG0765	amino acid transport
BH370_RS07915	COG1126	abc transporter atp-binding protein
BH370_RS07920	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BH370_RS07925	COG1758	RNA polymerase activity
BH370_RS07930	COG0194	GDP metabolic process
BH370_RS07935	COG3258	Cytochrome c
BH370_RS07940	COG2863	cytochrome
BH370_RS07945	COG1028	Short-chain dehydrogenase reductase Sdr
BH370_RS07950	COG0791	NLP P60 protein
BH370_RS07955	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BH370_RS07975	COG1561	YicC-like family, N-terminal region
BH370_RS07980	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BH370_RS07995	COG0840	transmembrane signaling receptor activity
BH370_RS08010	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BH370_RS08020	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BH370_RS08025	COG0174	glutamine synthetase
BH370_RS08035	COG2204	response regulator
BH370_RS08040	COG0583	DNA-binding transcription factor activity
BH370_RS08045	COG1741	Belongs to the pirin family
BH370_RS08050	COG1741	Belongs to the pirin family
BH370_RS08060	COG3842	ATPase activity
BH370_RS08065	COG1178	ABC-type Fe3 transport system permease component
BH370_RS08070	COG1840	ABC-type Fe3 transport system, periplasmic component
BH370_RS08080	COG0583	DNA-binding transcription factor activity
BH370_RS08090	COG0656	L-ascorbic acid biosynthetic process
BH370_RS08105	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BH370_RS08110	COG0583	DNA-binding transcription factor activity
BH370_RS08125	COG0783	Belongs to the Dps family
BH370_RS08160	COG0438	transferase activity, transferring glycosyl groups
BH370_RS08175	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BH370_RS08200	COG0300	oxidoreductase activity
BH370_RS08245	COG0861	Integral membrane protein TerC family
BH370_RS08250	COG1028	Short-chain dehydrogenase reductase Sdr
BH370_RS08270	COG0714	Associated with various cellular activities
BH370_RS08300	COG3119	arylsulfatase activity
BH370_RS08325	COG2197	response regulator
BH370_RS08335	COG2944	sequence-specific DNA binding
BH370_RS08345	COG0625	glutathione transferase activity
BH370_RS08375	COG0179	Fumarylacetoacetate (FAA) hydrolase
BH370_RS08380	COG1028	Short-chain dehydrogenase reductase Sdr
BH370_RS08425	COG0431	NADPH-dependent FMN reductase
BH370_RS08455	COG1028	Short-chain dehydrogenase reductase Sdr
BH370_RS08460	COG0583	DNA-binding transcription factor activity
BH370_RS08480	COG2111	Na H antiporter
BH370_RS08480	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BH370_RS08485	COG1006	Multisubunit Na H antiporter MnhC subunit
BH370_RS08490	COG0651	ATP synthesis coupled electron transport
BH370_RS08495	COG1863	multisubunit Na H antiporter MnhE subunit
BH370_RS08500	COG2212	antiporter activity
BH370_RS08525	COG0590	tRNA wobble adenosine to inosine editing
BH370_RS08530	COG1619	proteins homologs of microcin C7 resistance protein MccF
BH370_RS08535	COG1024	Enoyl-CoA hydratase
BH370_RS08550	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BH370_RS08555	COG0488	(ABC) transporter
BH370_RS08590	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BH370_RS08600	COG2252	PERMEase
BH370_RS08605	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BH370_RS08615	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BH370_RS08620	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BH370_RS08650	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BH370_RS08655	COG0789	Transcriptional regulator
BH370_RS08665	COG0678	peroxiredoxin activity
BH370_RS08665	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BH370_RS08675	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BH370_RS08680	COG0584	glycerophosphoryl diester phosphodiesterase
BH370_RS08685	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BH370_RS08705	COG2823	Periplasmic or secreted lipoprotein
BH370_RS08715	COG3237	CsbD-like
BH370_RS08720	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BH370_RS08720	COG1181	Belongs to the D-alanine--D-alanine ligase family
BH370_RS08725	COG0189	ligase activity
BH370_RS08725	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BH370_RS08745	COG2833	Protein of unknown function (DUF455)
BH370_RS08750	COG2951	lytic endotransglycosylase activity
BH370_RS08765	COG1522	sequence-specific DNA binding
BH370_RS08775	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BH370_RS08780	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BH370_RS08785	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BH370_RS08790	COG0196	riboflavin kinase activity
BH370_RS08795	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BH370_RS08820	COG0210	DNA helicase
BH370_RS08825	COG4771	TonB-dependent receptor
BH370_RS08830	COG0488	(ABC) transporter
BH370_RS08835	COG2890	protein-(glutamine-N5) methyltransferase activity
BH370_RS08840	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BH370_RS08845	COG2171	N-acyltransferase activity
BH370_RS08880	COG1278	Cold shock
BH370_RS08890	COG1278	Cold shock
BH370_RS08900	COG0544	peptidyl-prolyl cis-trans isomerase activity
BH370_RS08905	COG0740	serine-type endopeptidase activity
BH370_RS08910	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BH370_RS08915	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BH370_RS08920	COG0583	DNA-binding transcription factor activity
BH370_RS08925	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH370_RS08940	COG1024	Enoyl-CoA hydratase
BH370_RS08950	COG0183	Belongs to the thiolase family
BH370_RS08955	COG1028	Short-chain dehydrogenase reductase Sdr
BH370_RS08975	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BH370_RS09005	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BH370_RS09015	COG0556	nucleotide-excision repair
BH370_RS09020	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BH370_RS09030	COG1104	cysteine desulfurase activity
BH370_RS09035	COG0822	iron-sulfur transferase activity
BH370_RS09040	COG0316	Belongs to the HesB IscA family
BH370_RS09045	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BH370_RS09050	COG0443	Heat shock 70 kDa protein
BH370_RS09055	COG0633	Ferredoxin
BH370_RS09075	COG1024	Enoyl-CoA hydratase
BH370_RS09090	COG3395	kinase activity
BH370_RS09110	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BH370_RS09120	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BH370_RS09145	COG0747	negative chemotaxis
BH370_RS09150	COG0601	transmembrane transport
BH370_RS09155	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BH370_RS09160	COG4172	Belongs to the ABC transporter superfamily
BH370_RS09165	COG0154	amidase activity
BH370_RS09210	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BH370_RS09215	COG0425	Belongs to the sulfur carrier protein TusA family
BH370_RS09225	COG0228	four-way junction DNA binding
BH370_RS09230	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BH370_RS09235	COG0336	Belongs to the RNA methyltransferase TrmD family
BH370_RS09240	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BH370_RS09255	COG0642	Histidine kinase
BH370_RS09270	COG0525	valine-tRNA ligase activity
BH370_RS09275	COG0105	UTP biosynthetic process
BH370_RS09280	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BH370_RS09290	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BH370_RS09295	COG0124	histidyl-tRNA synthetase
BH370_RS09300	COG2976	Protein conserved in bacteria
BH370_RS09305	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BH370_RS09310	COG1160	GTP binding
BH370_RS09315	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BH370_RS09320	COG1923	regulation of RNA biosynthetic process
BH370_RS09325	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BH370_RS09330	COG0330	HflC and HflK could
BH370_RS09335	COG0330	HflC and HflK could
BH370_RS09340	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BH370_RS09345	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BH370_RS09355	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BH370_RS09365	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BH370_RS09390	COG0628	permease
BH370_RS09395	COG0842	Transport permease protein
BH370_RS09400	COG1131	(ABC) transporter
BH370_RS09470	COG0156	8-amino-7-oxononanoate synthase activity
BH370_RS09480	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BH370_RS09480	COG4106	trans-aconitate 2-methyltransferase activity
BH370_RS09485	COG1380	Effector of murein hydrolase LrgA
BH370_RS09500	COG3284	Transcriptional regulator
BH370_RS09505	COG1012	belongs to the aldehyde dehydrogenase family
BH370_RS09520	COG2733	membrane
BH370_RS09525	COG0583	DNA-binding transcription factor activity
BH370_RS09530	COG0384	phenazine biosynthesis protein PhzF
BH370_RS09535	COG5507	3-demethylubiquinone-9 3-methyltransferase
BH370_RS09540	COG2169	Transcriptional regulator
BH370_RS09570	COG0659	secondary active sulfate transmembrane transporter activity
BH370_RS09595	COG1132	(ABC) transporter
BH370_RS09640	COG2207	Transcriptional regulator
BH370_RS09770	COG2346	COG2346, Truncated hemoglobins
BH370_RS09795	COG0583	DNA-binding transcription factor activity
BH370_RS09810	COG0183	Belongs to the thiolase family
BH370_RS09825	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH370_RS09830	COG0633	Ferredoxin
BH370_RS09840	COG1024	Enoyl-CoA hydratase
BH370_RS09850	COG4638	Rieske (2fe-2S)
BH370_RS09860	COG0559	Belongs to the binding-protein-dependent transport system permease family
BH370_RS09880	COG2224	Isocitrate lyase
BH370_RS09885	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BH370_RS09885	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BH370_RS09900	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BH370_RS09905	COG0322	excinuclease ABC activity
BH370_RS09910	COG1472	Belongs to the glycosyl hydrolase 3 family
BH370_RS09915	COG0736	holo-[acyl-carrier-protein] synthase activity
BH370_RS09920	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BH370_RS09930	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BH370_RS09935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BH370_RS09960	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BH370_RS09975	COG2032	superoxide dismutase activity
BH370_RS09990	COG1024	Enoyl-CoA hydratase
BH370_RS10000	COG1802	Transcriptional regulator
BH370_RS10010	COG0183	Belongs to the thiolase family
BH370_RS10015	COG1942	4-Oxalocrotonate Tautomerase
BH370_RS10025	COG4176	ABC-type proline glycine betaine transport system permease component
BH370_RS10045	COG2814	Major facilitator Superfamily
BH370_RS10050	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BH370_RS10055	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BH370_RS10080	COG2814	Major facilitator Superfamily
BH370_RS10085	COG0495	leucyl-tRNA aminoacylation
BH370_RS10100	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BH370_RS10110	COG0154	amidase activity
BH370_RS10115	COG1250	3-hydroxyacyl-CoA dehydrogenase
BH370_RS10170	COG0427	acetyl-CoA hydrolase
BH370_RS10175	COG0583	DNA-binding transcription factor activity
BH370_RS10190	COG0730	response to heat
BH370_RS10195	COG0697	spore germination
BH370_RS10230	COG2885	chlorophyll binding
BH370_RS10255	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BH370_RS10260	COG3384	dioxygenase
BH370_RS10275	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BH370_RS10280	COG3474	cytochrome
BH370_RS10290	COG1595	DNA-templated transcription, initiation
BH370_RS10305	COG2204	response regulator
BH370_RS10345	COG4964	Belongs to the GSP D family
BH370_RS10395	COG1846	Transcriptional regulator
BH370_RS10400	COG4172	Belongs to the ABC transporter superfamily
BH370_RS10405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BH370_RS10410	COG0601	transmembrane transport
BH370_RS10415	COG0747	negative chemotaxis
BH370_RS10425	COG0598	Magnesium transport protein CorA
BH370_RS10430	COG0210	DNA helicase
BH370_RS10445	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BH370_RS10450	COG1012	belongs to the aldehyde dehydrogenase family
BH370_RS10455	COG0483	inositol monophosphate 1-phosphatase activity
BH370_RS10460	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BH370_RS10470	COG1045	serine acetyltransferase
BH370_RS10475	COG0166	Belongs to the GPI family
BH370_RS10490	COG2197	response regulator
BH370_RS10500	COG3181	Tripartite tricarboxylate transporter family receptor
BH370_RS10515	COG1017	nitric oxide dioxygenase activity
BH370_RS10515	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BH370_RS10530	COG1335	isochorismatase
BH370_RS10535	COG2309	aminopeptidase activity
BH370_RS10545	COG3473	Maleate cis-trans isomerase
BH370_RS10550	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BH370_RS10555	COG2080	2 iron, 2 sulfur cluster binding
BH370_RS10590	COG1846	Transcriptional regulator
BH370_RS10610	COG1649	PFAM Uncharacterised BCR, COG1649
BH370_RS10610	COG0726	polysaccharide deacetylase
BH370_RS10615	COG1215	transferase activity, transferring glycosyl groups
BH370_RS10625	COG1902	pentaerythritol trinitrate reductase activity
BH370_RS10650	COG0251	oxidation-reduction process
BH370_RS10660	COG1832	CoA-binding protein
BH370_RS10665	COG1414	Transcriptional regulator
BH370_RS10670	COG0446	pyridine nucleotide-disulphide oxidoreductase
BH370_RS10670	COG1902	pentaerythritol trinitrate reductase activity
BH370_RS10680	COG3842	ATPase activity
BH370_RS10710	COG0583	DNA-binding transcription factor activity
BH370_RS10720	COG1028	Short-chain dehydrogenase reductase Sdr
BH370_RS10725	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
BH370_RS10730	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BH370_RS10745	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BH370_RS10750	COG1250	3-hydroxyacyl-CoA dehydrogenase
BH370_RS10775	COG0527	aspartate kinase activity
BH370_RS10780	COG0037	tRNA processing
BH370_RS10790	COG0825	malonyl-CoA metabolic process
BH370_RS10800	COG0215	cysteine-tRNA ligase activity
BH370_RS10815	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BH370_RS10820	COG1968	undecaprenyl-diphosphatase activity
BH370_RS10825	COG1253	flavin adenine dinucleotide binding
BH370_RS10850	COG0668	transmembrane transport
BH370_RS10900	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BH370_RS10915	COG2831	hemolysin activation secretion protein
BH370_RS10920	COG3539	Fimbrial protein
BH370_RS10930	COG3121	Chaperone
BH370_RS10940	COG3210	domain, Protein
BH370_RS10940	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
BH370_RS10940	COG3064	Membrane
BH370_RS10945	COG2197	response regulator
BH370_RS10950	COG2205	protein histidine kinase activity
BH370_RS10950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BH370_RS10960	COG4336	lyase activity
BH370_RS11000	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BH370_RS11020	COG0028	Belongs to the TPP enzyme family
BH370_RS11035	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BH370_RS11045	COG1126	abc transporter atp-binding protein
BH370_RS11055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BH370_RS11070	COG0084	hydrolase, TatD family'
BH370_RS11075	COG0084	hydrolase, TatD family'
BH370_RS11080	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BH370_RS11085	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BH370_RS11090	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BH370_RS11110	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BH370_RS11115	COG1959	2 iron, 2 sulfur cluster binding
BH370_RS11120	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BH370_RS11120	COG1017	nitric oxide dioxygenase activity
BH370_RS11150	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BH370_RS11155	COG2358	TRAP transporter, solute receptor (TAXI family
BH370_RS11185	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BH370_RS11190	COG1366	Belongs to the anti-sigma-factor antagonist family
BH370_RS11195	COG2172	sigma factor antagonist activity
BH370_RS11200	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BH370_RS11210	COG2208	phosphoserine phosphatase activity
BH370_RS11210	COG2770	Histidine kinase
BH370_RS11235	COG1595	DNA-templated transcription, initiation
BH370_RS11250	COG4792	protein secretion
BH370_RS11255	COG4791	protein targeting
BH370_RS11260	COG4794	Type iii secretion
BH370_RS11265	COG4790	Type iii secretion
BH370_RS11300	COG4669	(LipO)protein
BH370_RS11365	COG4789	Type iii secretion
BH370_RS11395	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BH370_RS11400	COG0840	transmembrane signaling receptor activity
BH370_RS11405	COG2233	PERMEase
BH370_RS11430	COG1840	ABC-type Fe3 transport system, periplasmic component
BH370_RS11435	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BH370_RS11440	COG1178	ABC-type Fe3 transport system permease component
BH370_RS11445	COG3842	ATPase activity
BH370_RS11450	COG0583	DNA-binding transcription factor activity
BH370_RS11470	COG0501	Belongs to the peptidase M48B family
BH370_RS11480	COG0697	spore germination
BH370_RS11490	COG1846	Transcriptional regulator
BH370_RS11500	COG1566	PFAM secretion protein HlyD family protein
BH370_RS11505	COG2814	Major facilitator Superfamily
BH370_RS11510	COG0473	3-isopropylmalate dehydrogenase activity
BH370_RS11520	COG0747	negative chemotaxis
BH370_RS11530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BH370_RS11545	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BH370_RS11570	COG1012	belongs to the aldehyde dehydrogenase family
BH370_RS11580	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BH370_RS11585	COG1115	amino acid carrier protein
BH370_RS11590	COG0433	COG0433 Predicted ATPase
BH370_RS11595	COG0217	transcriptional regulatory protein
BH370_RS11600	COG0151	Belongs to the GarS family
BH370_RS11605	COG0408	coproporphyrinogen oxidase activity
BH370_RS11610	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BH370_RS11615	COG0799	negative regulation of ribosome biogenesis
BH370_RS11620	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BH370_RS11625	COG0424	maF-like protein
BH370_RS11630	COG3468	outer membrane autotransporter barrel domain protein
BH370_RS11670	COG1530	ribonuclease E activity
BH370_RS11675	COG0077	Prephenate dehydratase
BH370_RS11690	COG1132	(ABC) transporter
BH370_RS11695	COG0859	PFAM glycosyl transferase family 9
BH370_RS11720	COG2194	sulfuric ester hydrolase activity
BH370_RS11725	COG0438	transferase activity, transferring glycosyl groups
BH370_RS11730	COG0463	Glycosyl transferase, family 2
BH370_RS11735	COG0726	polysaccharide deacetylase
BH370_RS11740	COG0438	transferase activity, transferring glycosyl groups
BH370_RS11755	COG1643	Atp-dependent helicase
BH370_RS11760	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BH370_RS11760	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BH370_RS11765	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
BH370_RS11775	COG0704	Plays a role in the regulation of phosphate uptake
BH370_RS11780	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BH370_RS11785	COG1960	acyl-CoA dehydrogenase activity
BH370_RS11810	COG1177	transmembrane transport
BH370_RS11815	COG1176	ABC-type spermidine putrescine transport system, permease component I
BH370_RS11820	COG3842	ATPase activity
BH370_RS11825	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BH370_RS11840	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BH370_RS11845	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BH370_RS11875	COG0372	Belongs to the citrate synthase family
BH370_RS11880	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BH370_RS11885	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BH370_RS11890	COG1053	succinate dehydrogenase
BH370_RS11895	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BH370_RS11900	COG2009	succinate dehydrogenase
BH370_RS11905	COG2188	Transcriptional regulator
BH370_RS11910	COG0039	L-malate dehydrogenase activity
BH370_RS11965	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BH370_RS11975	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BH370_RS12005	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BH370_RS12010	COG0148	phosphopyruvate hydratase activity
BH370_RS12020	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BH370_RS12025	COG0504	CTP synthase activity
BH370_RS12050	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BH370_RS12060	COG0747	negative chemotaxis
BH370_RS12065	COG4172	Belongs to the ABC transporter superfamily
BH370_RS12070	COG1446	asparaginase
BH370_RS12100	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BH370_RS12115	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
BH370_RS12120	COG0697	spore germination
BH370_RS12125	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BH370_RS12135	COG3193	protein, possibly involved in utilization of glycolate and propanediol
BH370_RS12145	COG0791	NLP P60 protein
BH370_RS12160	COG0583	DNA-binding transcription factor activity
BH370_RS12175	COG0583	DNA-binding transcription factor activity
BH370_RS12185	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BH370_RS12200	COG0670	Belongs to the BI1 family
BH370_RS12205	COG3181	Tripartite tricarboxylate transporter family receptor
BH370_RS12230	COG1381	Involved in DNA repair and RecF pathway recombination
BH370_RS12235	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BH370_RS12240	COG0571	ribonuclease III activity
BH370_RS12245	COG0681	Belongs to the peptidase S26 family
BH370_RS12250	COG0481	GTPase activity
BH370_RS12255	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BH370_RS12280	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BH370_RS12285	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BH370_RS12300	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BH370_RS12305	COG0416	fatty acid biosynthetic process
BH370_RS12310	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BH370_RS12315	COG1399	metal-binding, possibly nucleic acid-binding protein
BH370_RS12320	COG0424	maF-like protein
BH370_RS12330	COG3023	N-Acetylmuramoyl-L-alanine amidase
BH370_RS12335	COG1289	transmembrane transporter activity
BH370_RS12345	COG3022	response to hydroperoxide
BH370_RS12355	COG1028	Short-chain dehydrogenase reductase Sdr
BH370_RS12370	COG3486	L-lysine 6-monooxygenase (NADPH) activity
BH370_RS12400	COG2814	Major facilitator Superfamily
BH370_RS12420	COG3706	GGDEF domain
BH370_RS12445	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BH370_RS12450	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BH370_RS12455	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BH370_RS12460	COG1674	ftsk spoiiie
BH370_RS12465	COG0492	ferredoxin-NADP+ reductase activity
BH370_RS12470	COG1193	negative regulation of DNA recombination
BH370_RS12485	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BH370_RS12500	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BH370_RS12505	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BH370_RS12510	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
BH370_RS12520	COG0745	RESPONSE REGULATOR receiver
BH370_RS12565	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BH370_RS12585	COG0612	Peptidase, M16
BH370_RS12595	COG0443	Heat shock 70 kDa protein
BH370_RS12605	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BH370_RS12615	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BH370_RS12620	COG1420	regulation of RNA biosynthetic process
BH370_RS12625	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BH370_RS12630	COG0497	DNA recombination
BH370_RS12635	COG0735	belongs to the Fur family
BH370_RS12640	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BH370_RS12645	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BH370_RS12650	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BH370_RS12685	COG0446	pyridine nucleotide-disulphide oxidoreductase
BH370_RS12685	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BH370_RS12690	COG4311	Sarcosine oxidase, delta subunit
BH370_RS12695	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BH370_RS12705	COG0583	DNA-binding transcription factor activity
BH370_RS12715	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BH370_RS12745	COG4964	Belongs to the GSP D family
BH370_RS12805	COG0181	hydroxymethylbilane synthase activity
BH370_RS12810	COG0861	Integral membrane protein TerC family
BH370_RS12815	COG0861	Integral membrane protein TerC family
BH370_RS12820	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BH370_RS12825	COG0045	succinate-CoA ligase (ADP-forming) activity
BH370_RS12835	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BH370_RS12845	COG2137	regulation of response to DNA damage stimulus
BH370_RS12850	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BH370_RS12860	COG0642	Histidine kinase
BH370_RS12870	COG1024	Enoyl-CoA hydratase
BH370_RS12870	COG1250	3-hydroxyacyl-CoA dehydrogenase
BH370_RS12875	COG3842	ATPase activity
BH370_RS12890	COG1028	Short-chain dehydrogenase reductase Sdr
BH370_RS12910	COG0583	DNA-binding transcription factor activity
BH370_RS12915	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH370_RS12925	COG2974	May be involved in recombination
BH370_RS12930	COG0540	Belongs to the ATCase OTCase family
BH370_RS13000	COG0776	regulation of translation
BH370_RS13005	COG0072	phenylalanine-tRNA ligase activity
BH370_RS13005	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BH370_RS13010	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BH370_RS13015	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BH370_RS13020	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BH370_RS13030	COG0756	dUTP diphosphatase activity
BH370_RS13040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BH370_RS13055	COG0500	methyltransferase
BH370_RS13065	COG0586	Pfam SNARE associated Golgi protein
BH370_RS13090	COG1609	Transcriptional regulator
BH370_RS13095	COG4172	Belongs to the ABC transporter superfamily
BH370_RS13105	COG0601	transmembrane transport
BH370_RS13110	COG0747	negative chemotaxis
BH370_RS13125	COG1280	lysine exporter protein (LysE YggA)
BH370_RS13140	COG2814	Major facilitator Superfamily
BH370_RS13170	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BH370_RS13185	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BH370_RS13210	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BH370_RS13215	COG1116	anion transmembrane transporter activity
BH370_RS13225	COG1228	amidohydrolase
BH370_RS13240	COG0477	Major facilitator Superfamily
BH370_RS13250	COG3550	peptidyl-serine autophosphorylation
BH370_RS13260	COG0519	Catalyzes the synthesis of GMP from XMP
BH370_RS13260	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BH370_RS13310	COG0420	3'-5' exonuclease activity
BH370_RS13315	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BH370_RS13350	COG0395	ABC-type sugar transport system, permease component
BH370_RS13390	COG3181	Tripartite tricarboxylate transporter family receptor
BH370_RS13425	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BH370_RS13450	COG0602	queuosine metabolic process
BH370_RS13455	COG0720	synthase
BH370_RS13460	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BH370_RS13465	COG0235	Class ii aldolase
BH370_RS13490	COG3210	domain, Protein
BH370_RS13490	COG3064	Membrane
BH370_RS13490	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
BH370_RS13495	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BH370_RS13495	COG0047	phosphoribosylformylglycinamidine synthase activity
BH370_RS13500	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BH370_RS13505	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BH370_RS13510	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BH370_RS13530	COG3539	Fimbrial protein
BH370_RS13540	COG2050	protein possibly involved in aromatic compounds catabolism
BH370_RS13545	COG1024	Enoyl-CoA hydratase
BH370_RS13550	COG1012	belongs to the aldehyde dehydrogenase family
BH370_RS13560	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BH370_RS13565	COG2151	metal-sulfur cluster biosynthetic enzyme
BH370_RS13570	COG3396	Phenylacetate-CoA oxygenase
BH370_RS13575	COG3460	Phenylacetate-CoA oxygenase
BH370_RS13580	COG3396	Phenylacetate-CoA oxygenase
BH370_RS13585	COG3327	negative regulation of DNA-templated transcription, initiation
BH370_RS13595	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BH370_RS13600	COG0501	Belongs to the peptidase M48B family
BH370_RS13605	COG1162	GTPase activity
BH370_RS13615	COG0601	transmembrane transport
BH370_RS13620	COG0747	negative chemotaxis
BH370_RS13665	COG0668	transmembrane transport
BH370_RS13670	COG0165	Argininosuccinate lyase
BH370_RS13690	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BH370_RS13695	COG0303	'Molybdopterin
BH370_RS13700	COG0521	Mo-molybdopterin cofactor biosynthetic process
BH370_RS13715	COG0315	cyclic pyranopterin monophosphate synthase activity
BH370_RS13725	COG0412	Dienelactone hydrolase
BH370_RS13735	COG0678	peroxiredoxin activity
BH370_RS13745	COG0697	spore germination
BH370_RS13750	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BH370_RS13775	COG0789	Transcriptional regulator
BH370_RS13795	COG1028	Short-chain dehydrogenase reductase Sdr
BH370_RS13805	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BH370_RS13810	COG1845	cytochrome c oxidase, subunit III
BH370_RS13815	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BH370_RS13825	COG0477	Major facilitator Superfamily
BH370_RS13865	COG1309	transcriptional regulator
BH370_RS13870	COG2271	Major facilitator Superfamily
BH370_RS13905	COG0506	proline dehydrogenase activity
BH370_RS13905	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BH370_RS13905	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BH370_RS13915	COG3008	intermembrane lipid transfer
BH370_RS13915	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BH370_RS13920	COG2995	paraquat-inducible protein a
BH370_RS13925	COG0542	response to heat
BH370_RS13930	COG4953	penicillin-binding protein 1C
BH370_RS13940	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BH370_RS13945	COG1278	Cold shock
BH370_RS13955	COG0183	Belongs to the thiolase family
BH370_RS13960	COG0038	chloride channel
BH370_RS13965	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BH370_RS13970	COG1570	exodeoxyribonuclease VII activity
BH370_RS13980	COG0811	peptide transport
BH370_RS13985	COG0848	biopolymer transport protein
BH370_RS13990	COG1663	tetraacyldisaccharide 4'-kinase activity
BH370_RS13995	COG2835	tetraacyldisaccharide 4'-kinase activity
BH370_RS14000	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BH370_RS14005	COG0563	adenylate kinase activity
BH370_RS14015	COG0728	peptidoglycan biosynthetic process
BH370_RS14025	COG0268	Binds directly to 16S ribosomal RNA
BH370_RS14055	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BH370_RS14080	COG0436	Aminotransferase
BH370_RS14085	COG3737	Protein of unknown function (DUF498/DUF598)
BH370_RS14090	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BH370_RS14095	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BH370_RS14100	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BH370_RS14110	COG0305	Participates in initiation and elongation during chromosome replication
BH370_RS14120	COG0359	binds to the 23S rRNA
BH370_RS14125	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BH370_RS14130	COG2965	DNA replication, synthesis of RNA primer
BH370_RS14135	COG0360	Binds together with S18 to 16S ribosomal RNA
BH370_RS14140	COG1469	GTP cyclohydrolase I activity
BH370_RS14145	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BH370_RS14150	COG0142	geranyltranstransferase activity
BH370_RS14155	COG1722	exodeoxyribonuclease VII activity
BH370_RS14165	COG3181	Tripartite tricarboxylate transporter family receptor
BH370_RS14185	COG2239	Acts as a magnesium transporter
BH370_RS14195	COG2855	membrane
BH370_RS14205	COG1473	amidohydrolase
BH370_RS14210	COG0318	PFAM AMP-dependent synthetase and ligase
BH370_RS14230	COG1501	Belongs to the glycosyl hydrolase 31 family
BH370_RS14235	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BH370_RS14240	COG2011	ABC-type metal ion transport system permease component
BH370_RS14260	COG1454	alcohol dehydrogenase
BH370_RS14285	COG2186	Transcriptional regulator
BH370_RS14290	COG3181	Tripartite tricarboxylate transporter family receptor
BH370_RS14310	COG1175	transmembrane transport
BH370_RS14315	COG0395	ABC-type sugar transport system, permease component
BH370_RS14320	COG3842	ATPase activity
BH370_RS14335	COG1653	transport
BH370_RS14355	COG2818	Glycosylase
BH370_RS14360	COG2982	Protein involved in outer membrane biogenesis
BH370_RS14370	COG1309	transcriptional regulator
BH370_RS14375	COG1028	Short-chain dehydrogenase reductase Sdr
BH370_RS14420	COG0583	DNA-binding transcription factor activity
BH370_RS14425	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BH370_RS14430	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BH370_RS14445	COG1028	Short-chain dehydrogenase reductase Sdr
BH370_RS14450	COG0477	Major facilitator Superfamily
BH370_RS14460	COG0583	DNA-binding transcription factor activity
BH370_RS14465	COG1448	Aminotransferase
BH370_RS14470	COG1418	mRNA catabolic process
BH370_RS14495	COG1063	alcohol dehydrogenase
BH370_RS14515	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BH370_RS14525	COG0318	PFAM AMP-dependent synthetase and ligase
BH370_RS14535	COG1522	sequence-specific DNA binding
BH370_RS14540	COG3181	Tripartite tricarboxylate transporter family receptor
BH370_RS14545	COG0307	riboflavin synthase, alpha
BH370_RS14550	COG0154	amidase activity
BH370_RS14570	COG2807	transmembrane transport
BH370_RS14575	COG0590	tRNA wobble adenosine to inosine editing
BH370_RS14585	COG0583	DNA-binding transcription factor activity
BH370_RS14620	COG0559	Belongs to the binding-protein-dependent transport system permease family
BH370_RS14625	COG0251	oxidation-reduction process
BH370_RS14640	COG1414	Transcriptional regulator
BH370_RS14645	COG1028	Short-chain dehydrogenase reductase Sdr
BH370_RS14660	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BH370_RS14675	COG1024	Enoyl-CoA hydratase
BH370_RS14680	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH370_RS14725	COG3909	cytochrome
BH370_RS14730	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BH370_RS14735	COG0625	glutathione transferase activity
BH370_RS14740	COG0730	response to heat
BH370_RS14745	COG0482	sulfurtransferase activity
BH370_RS14750	COG0583	DNA-binding transcription factor activity
BH370_RS14785	COG2819	hydrolase of the alpha beta superfamily
BH370_RS14790	COG0247	lactate metabolic process
BH370_RS14795	COG0277	FAD linked oxidase domain protein
BH370_RS14800	COG0277	FAD linked oxidase domain protein
BH370_RS14805	COG0277	FAD linked oxidase domain protein
BH370_RS14810	COG3064	Membrane
BH370_RS14810	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
BH370_RS14810	COG3210	domain, Protein
BH370_RS14810	COG3210	domain, Protein
BH370_RS14810	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
BH370_RS14810	COG3064	Membrane
BH370_RS14815	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BH370_RS14820	COG0312	modulator of DNA gyrase
BH370_RS14855	COG1666	GTP binding
BH370_RS14900	COG3220	belongs to the UPF0276 family
BH370_RS14920	COG0640	Transcriptional regulator
BH370_RS14925	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BH370_RS14930	COG1845	cytochrome c oxidase, subunit III
BH370_RS14935	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BH370_RS14945	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BH370_RS14985	COG0583	DNA-binding transcription factor activity
BH370_RS15015	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BH370_RS15015	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BH370_RS15030	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BH370_RS15035	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BH370_RS15045	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BH370_RS15060	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BH370_RS15065	COG0316	Belongs to the HesB IscA family
BH370_RS15075	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BH370_RS15080	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BH370_RS15085	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BH370_RS15090	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BH370_RS15095	COG0312	modulator of DNA gyrase
BH370_RS15100	COG3028	Belongs to the UPF0307 family
BH370_RS15115	COG1116	anion transmembrane transporter activity
BH370_RS15120	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BH370_RS15125	COG1335	isochorismatase
BH370_RS15130	COG0346	lactoylglutathione lyase activity
BH370_RS15135	COG0513	Belongs to the DEAD box helicase family
BH370_RS15140	COG3069	C4-dicarboxylate transmembrane transporter activity
BH370_RS15145	COG1802	Transcriptional regulator
BH370_RS15155	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BH370_RS15155	COG0045	succinate-CoA ligase (ADP-forming) activity
BH370_RS15155	COG1042	CoA-binding domain protein
BH370_RS15160	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BH370_RS15175	COG1522	sequence-specific DNA binding
BH370_RS15210	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BH370_RS15215	COG1696	Membrane protein involved in D-alanine export
BH370_RS15240	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BH370_RS15255	COG0439	Biotin carboxylase
BH370_RS15260	COG0511	ligase activity, forming carbon-carbon bonds
BH370_RS15265	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BH370_RS15270	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BH370_RS15275	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BH370_RS15280	COG3150	esterase
BH370_RS15285	COG0557	exoribonuclease II activity
BH370_RS15295	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BH370_RS15320	COG1522	sequence-specific DNA binding
BH370_RS15325	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BH370_RS15330	COG1028	Short-chain dehydrogenase reductase Sdr
BH370_RS15350	COG0653	protein targeting
BH370_RS15355	COG0739	heme binding
BH370_RS15365	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BH370_RS15370	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BH370_RS15380	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BH370_RS15385	COG1181	Belongs to the D-alanine--D-alanine ligase family
BH370_RS15390	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BH370_RS15395	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BH370_RS15405	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BH370_RS15410	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BH370_RS15415	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BH370_RS15425	COG3116	cell division
BH370_RS15430	COG0275	rRNA processing
BH370_RS15435	COG2001	Belongs to the MraZ family
BH370_RS15450	COG0418	dihydroorotase activity
BH370_RS15455	COG1473	amidohydrolase
BH370_RS15505	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BH370_RS15510	COG4654	Cytochrome c, class I
BH370_RS15515	COG0129	dihydroxy-acid dehydratase activity
BH370_RS15520	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BH370_RS15570	COG2084	Dehydrogenase
BH370_RS15585	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BH370_RS15590	COG0513	Belongs to the DEAD box helicase family
BH370_RS15600	COG0617	tRNA 3'-terminal CCA addition
BH370_RS15615	COG0477	Major facilitator Superfamily
BH370_RS15625	COG0583	DNA-binding transcription factor activity
BH370_RS15640	COG1950	PFAM Membrane protein of
BH370_RS15645	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BH370_RS15660	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BH370_RS15670	COG1560	Kdo2-lipid A biosynthetic process
BH370_RS15675	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BH370_RS15685	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BH370_RS15695	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
BH370_RS15705	COG0803	Belongs to the bacterial solute-binding protein 9 family
BH370_RS15725	COG0735	belongs to the Fur family
BH370_RS15730	COG0523	cobalamin synthesis protein
BH370_RS15740	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BH370_RS15745	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BH370_RS15755	COG2096	Adenosyltransferase
BH370_RS15765	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BH370_RS15770	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BH370_RS15815	COG4772	TonB-dependent receptor
BH370_RS15845	COG0405	Gamma-glutamyltransferase
BH370_RS15855	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BH370_RS15880	COG1309	transcriptional regulator
BH370_RS15895	COG0745	RESPONSE REGULATOR receiver
BH370_RS15940	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BH370_RS15960	COG0582	viral genome integration into host DNA
BH370_RS15965	COG0012	GTP binding
BH370_RS15975	COG0193	aminoacyl-tRNA hydrolase activity
BH370_RS15980	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BH370_RS15985	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BH370_RS15995	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BH370_RS16000	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BH370_RS16010	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BH370_RS16035	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
BH370_RS16045	COG1368	sulfuric ester hydrolase activity
BH370_RS16050	COG0642	Histidine kinase
BH370_RS16055	COG0745	RESPONSE REGULATOR receiver
BH370_RS16060	COG0277	FAD linked oxidase domain protein
BH370_RS16075	COG0166	Belongs to the GPI family
BH370_RS16080	COG0438	transferase activity, transferring glycosyl groups
BH370_RS16085	COG0438	transferase activity, transferring glycosyl groups
BH370_RS16100	COG0438	transferase activity, transferring glycosyl groups
BH370_RS16115	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BH370_RS16120	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BH370_RS16125	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
BH370_RS16135	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BH370_RS16145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BH370_RS16160	COG0747	negative chemotaxis
BH370_RS16165	COG0601	transmembrane transport
BH370_RS16170	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BH370_RS16190	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BH370_RS16195	COG0830	nickel cation binding
BH370_RS16205	COG0804	urea catabolic process
BH370_RS16210	COG0832	Belongs to the urease beta subunit family
BH370_RS16220	COG0831	urea catabolic process
BH370_RS16225	COG0829	nickel cation binding
BH370_RS16250	COG2188	Transcriptional regulator
BH370_RS16275	COG2719	SpoVR family
BH370_RS16280	COG2718	Belongs to the UPF0229 family
BH370_RS16300	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH370_RS16315	COG1960	acyl-CoA dehydrogenase activity
BH370_RS16365	COG2030	dehydratase
BH370_RS16410	COG0328	RNA-DNA hybrid ribonuclease activity
BH370_RS16415	COG2226	methyltransferase
BH370_RS16420	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BH370_RS16425	COG1388	LysM domain
BH370_RS16425	COG0741	lytic transglycosylase activity
BH370_RS16445	COG2979	Protein of unknown function (DUF533)
BH370_RS16465	COG0745	RESPONSE REGULATOR receiver
BH370_RS16480	COG1271	oxidase subunit
BH370_RS16485	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BH370_RS16490	COG0850	regulation of cytokinetic process
BH370_RS16495	COG2894	cell division
BH370_RS16500	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BH370_RS16530	COG0601	transmembrane transport
BH370_RS16540	COG1215	transferase activity, transferring glycosyl groups
BH370_RS16555	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BH370_RS16565	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BH370_RS16585	COG0318	PFAM AMP-dependent synthetase and ligase
BH370_RS16590	COG2188	Transcriptional regulator
BH370_RS16595	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BH370_RS16600	COG2814	Major facilitator Superfamily
BH370_RS16610	COG0259	pyridoxamine-phosphate oxidase activity
BH370_RS16615	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BH370_RS16630	COG0583	DNA-binding transcription factor activity
BH370_RS16660	COG0134	indole-3-glycerol-phosphate synthase activity
BH370_RS16665	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BH370_RS16670	COG0512	Glutamine amidotransferase of anthranilate synthase
BH370_RS16680	COG0546	phosphoglycolate phosphatase activity
BH370_RS16685	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BH370_RS16690	COG2967	ApaG domain
BH370_RS16695	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
BH370_RS16700	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BH370_RS16705	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BH370_RS16710	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BH370_RS16720	COG0037	tRNA processing
BH370_RS16730	COG3634	alkyl hydroperoxide reductase activity
BH370_RS16735	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BH370_RS16740	COG1024	Enoyl-CoA hydratase
BH370_RS16765	COG0356	it plays a direct role in the translocation of protons across the membrane
BH370_RS16775	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BH370_RS16780	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BH370_RS16785	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BH370_RS16790	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BH370_RS16795	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BH370_RS16800	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BH370_RS16810	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BH370_RS16815	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BH370_RS16820	COG0210	DNA helicase
BH370_RS16830	COG2195	Cleaves the N-terminal amino acid of tripeptides
BH370_RS16845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BH370_RS16850	COG0601	transmembrane transport
BH370_RS16870	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BH370_RS16875	COG1024	Enoyl-CoA hydratase
BH370_RS16880	COG1024	Enoyl-CoA hydratase
BH370_RS16945	COG1024	Enoyl-CoA hydratase
BH370_RS16945	COG1250	3-hydroxyacyl-CoA dehydrogenase
BH370_RS16960	COG1414	Transcriptional regulator
BH370_RS16970	COG0154	amidase activity
BH370_RS17000	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BH370_RS17005	COG3568	Endonuclease Exonuclease Phosphatase
BH370_RS17010	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BH370_RS17045	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BH370_RS17055	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BH370_RS17070	COG1137	ATPase activity
BH370_RS17085	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BH370_RS17090	COG2010	Cytochrome c
BH370_RS17090	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BH370_RS17100	COG1660	Displays ATPase and GTPase activities
BH370_RS17105	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BH370_RS17145	COG3181	Tripartite tricarboxylate transporter family receptor
BH370_RS17155	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BH370_RS17160	COG2890	protein-(glutamine-N5) methyltransferase activity
BH370_RS17165	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BH370_RS17170	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BH370_RS17210	COG1960	acyl-CoA dehydrogenase activity
BH370_RS17220	COG0183	Belongs to the thiolase family
BH370_RS17225	COG1522	sequence-specific DNA binding
BH370_RS17230	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BH370_RS17250	COG1024	Enoyl-CoA hydratase
BH370_RS17265	COG0604	alcohol dehydrogenase
BH370_RS17270	COG2072	flavoprotein involved in K transport
BH370_RS17285	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BH370_RS17295	COG1960	acyl-CoA dehydrogenase activity
BH370_RS17300	COG1960	acyl-CoA dehydrogenase activity
BH370_RS17305	COG0277	FAD linked oxidase domain protein
BH370_RS17315	COG3181	Tripartite tricarboxylate transporter family receptor
BH370_RS17335	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BH370_RS17345	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH370_RS17350	COG3181	Tripartite tricarboxylate transporter family receptor
BH370_RS17355	COG1960	acyl-CoA dehydrogenase activity
BH370_RS17375	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BH370_RS17380	COG1024	Enoyl-CoA hydratase
BH370_RS17385	COG1960	acyl-CoA dehydrogenase activity
BH370_RS17405	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BH370_RS17410	COG0022	dehydrogenase e1 component
BH370_RS17415	COG1024	Enoyl-CoA hydratase
BH370_RS17420	COG0508	dehydrogenase complex catalyzes the overall conversion of
BH370_RS17440	COG0683	leucine binding
BH370_RS17445	COG0559	Belongs to the binding-protein-dependent transport system permease family
BH370_RS17450	COG0411	ABC transporter
BH370_RS17460	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BH370_RS17475	COG3181	Tripartite tricarboxylate transporter family receptor
BH370_RS17500	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BH370_RS17505	COG0793	Belongs to the peptidase S41A family
BH370_RS17510	COG4942	peptidase
BH370_RS17515	COG0588	phosphoglycerate mutase activity
BH370_RS17525	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BH370_RS17530	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BH370_RS17535	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BH370_RS17540	COG3181	Tripartite tricarboxylate transporter family receptor
BH370_RS17555	COG2226	methyltransferase
BH370_RS17560	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
BH370_RS17575	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BH370_RS17580	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BH370_RS17605	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BH370_RS17630	COG1335	isochorismatase
BH370_RS17635	COG2309	aminopeptidase activity
BH370_RS17645	COG3473	Maleate cis-trans isomerase
BH370_RS17655	COG2068	MobA-Related Protein
BH370_RS17680	COG2204	response regulator
BH370_RS17685	COG5000	phosphorelay sensor kinase activity
BH370_RS17695	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BH370_RS17695	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BH370_RS17705	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
BH370_RS17725	COG0583	DNA-binding transcription factor activity
BH370_RS17745	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BH370_RS17750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BH370_RS17765	COG0758	DNA mediated transformation
BH370_RS17770	COG1522	sequence-specific DNA binding
BH370_RS17780	COG0242	peptide deformylase activity
BH370_RS17790	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BH370_RS17800	COG0546	phosphoglycolate phosphatase activity
BH370_RS17820	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BH370_RS17825	COG1942	4-Oxalocrotonate Tautomerase
BH370_RS17830	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BH370_RS17855	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BH370_RS17875	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BH370_RS17880	COG1024	Enoyl-CoA hydratase
BH370_RS17885	COG1414	Transcriptional regulator
BH370_RS17890	COG0318	PFAM AMP-dependent synthetase and ligase
BH370_RS17895	COG3181	Tripartite tricarboxylate transporter family receptor
BH370_RS17940	COG3422	double-strand break repair
BH370_RS17945	COG0330	HflC and HflK could
BH370_RS17955	COG0251	oxidation-reduction process
BH370_RS18000	COG3723	Recombinational DNA repair protein, rece pathway
BH370_RS18035	COG0582	viral genome integration into host DNA
BH370_RS18070	COG0706	membrane insertase activity
BH370_RS18075	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BH370_RS18080	COG0594	ribonuclease P activity
BH370_RS18085	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BH370_RS18090	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BH370_RS18105	COG1414	Transcriptional regulator
BH370_RS18110	COG0154	amidase activity
BH370_RS18125	COG1304	FMN binding
BH370_RS18175	COG0183	Belongs to the thiolase family
BH370_RS18180	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BH370_RS18195	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BH370_RS18200	COG3181	Tripartite tricarboxylate transporter family receptor
BH370_RS18210	COG2358	TRAP transporter, solute receptor (TAXI family
BH370_RS18220	COG1629	transport
BH370_RS18225	COG2922	Belongs to the Smg family
BH370_RS18250	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BH370_RS18255	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BH370_RS18260	COG1028	Short-chain dehydrogenase reductase Sdr
BH370_RS18265	COG1012	belongs to the aldehyde dehydrogenase family
BH370_RS18275	COG0028	Belongs to the TPP enzyme family
BH370_RS18280	COG1522	sequence-specific DNA binding
BH370_RS18285	COG3781	membrane
BH370_RS18295	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BH370_RS18315	COG4206	TonB-dependent receptor
BH370_RS18320	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BH370_RS18325	COG2022	thiamine diphosphate biosynthetic process
BH370_RS18330	COG0351	phosphomethylpyrimidine kinase
BH370_RS18335	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BH370_RS18350	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BH370_RS18360	COG0628	permease
BH370_RS18370	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BH370_RS18380	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BH370_RS18385	COG0049	tRNA binding
BH370_RS18390	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BH370_RS18395	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BH370_RS18400	COG0051	transcription antitermination factor activity, RNA binding
BH370_RS18405	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BH370_RS18410	COG0088	Forms part of the polypeptide exit tunnel
BH370_RS18415	COG0089	rRNA binding
BH370_RS18420	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BH370_RS18425	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BH370_RS18430	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BH370_RS18435	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BH370_RS18440	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BH370_RS18445	COG0255	Belongs to the universal ribosomal protein uL29 family
BH370_RS18450	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BH370_RS18470	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BH370_RS18475	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BH370_RS18480	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BH370_RS18485	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BH370_RS18490	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BH370_RS18495	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BH370_RS18500	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BH370_RS18505	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BH370_RS18510	COG1841	ribosomal large subunit assembly
BH370_RS18515	COG0200	Binds to the 23S rRNA
BH370_RS18520	COG0201	protein transport
BH370_RS18525	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BH370_RS18530	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BH370_RS18535	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BH370_RS18540	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BH370_RS18545	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BH370_RS18550	COG0202	RNA polymerase activity
BH370_RS18555	COG0203	ribosomal protein L17
BH370_RS18565	COG1324	tolerance protein
BH370_RS18570	COG4232	protein-disulfide reductase activity
BH370_RS18585	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BH370_RS18595	COG1333	cytochrome c biogenesis protein
BH370_RS18600	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BH370_RS18610	COG1965	Belongs to the frataxin family
BH370_RS18620	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BH370_RS18625	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BH370_RS18630	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BH370_RS18645	COG2814	Major facilitator Superfamily
BH370_RS18650	COG0629	single-stranded DNA binding
BH370_RS18690	COG0402	S-adenosylhomocysteine deaminase activity
BH370_RS18700	COG0438	transferase activity, transferring glycosyl groups
BH370_RS18720	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BH370_RS18745	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BH370_RS18770	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BH370_RS18775	COG1956	GAF domain-containing protein
BH370_RS18780	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BH370_RS18790	COG1652	LysM domain
BH370_RS18805	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BH370_RS18820	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BH370_RS18845	COG3181	Tripartite tricarboxylate transporter family receptor
BH370_RS18860	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BH370_RS18875	COG1024	Enoyl-CoA hydratase
BH370_RS18890	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH370_RS18895	COG1309	transcriptional regulator
BH370_RS18900	COG2816	NAD+ diphosphatase activity
BH370_RS18905	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BH370_RS18990	COG2814	Major facilitator Superfamily
BH370_RS18995	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BH370_RS19015	COG1999	signal sequence binding
BH370_RS19020	COG0109	protoheme IX farnesyltransferase activity
BH370_RS19060	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BH370_RS19080	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BH370_RS19085	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BH370_RS19095	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BH370_RS19100	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
BH370_RS19110	COG0070	glutamate synthase
BH370_RS19110	COG0069	glutamate synthase activity
BH370_RS19110	COG0067	glutamate synthase
BH370_RS19120	COG3047	cAMP biosynthetic process
BH370_RS19130	COG1127	ABC transporter
BH370_RS19135	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BH370_RS19140	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BH370_RS19145	COG2853	Lipoprotein
BH370_RS19175	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BH370_RS19180	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BH370_RS19185	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BH370_RS19190	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BH370_RS19195	COG0131	Imidazoleglycerol-phosphate dehydratase
BH370_RS19200	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BH370_RS19205	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BH370_RS19210	COG0107	imidazoleglycerol-phosphate synthase activity
BH370_RS19215	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BH370_RS19220	COG0140	phosphoribosyl-ATP diphosphatase activity
BH370_RS19225	COG0537	adenosine 5'-monophosphoramidase activity
BH370_RS19230	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BH370_RS19235	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BH370_RS19250	COG3181	Tripartite tricarboxylate transporter family receptor
BH370_RS19285	COG3702	type iv secretory pathway
BH370_RS19290	COG3451	type IV secretory pathway VirB4
BH370_RS19305	COG3736	Type IV secretory pathway, component VirB8
BH370_RS19310	COG3504	Conjugal transfer protein
BH370_RS19315	COG2948	multi-organism process
BH370_RS19320	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
BH370_RS19330	COG0697	spore germination
BH370_RS19350	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BH370_RS19355	COG0747	negative chemotaxis
BH370_RS19365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BH370_RS19380	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BH370_RS19390	COG0494	nUDIX hydrolase
BH370_RS19425	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
BH370_RS19430	COG0237	dephospho-CoA kinase activity
BH370_RS19435	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BH370_RS19450	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BH370_RS19455	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BH370_RS19465	COG0477	Major facilitator Superfamily
BH370_RS19470	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BH370_RS19485	COG1126	abc transporter atp-binding protein
BH370_RS19490	COG0765	amino acid transport
BH370_RS19495	COG4597	amino acid ABC transporter
BH370_RS19500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BH370_RS19505	COG2884	Cell division ATP-binding protein ftsE
BH370_RS19510	COG2177	Part of the ABC transporter FtsEX involved in
BH370_RS19515	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BH370_RS19525	COG1194	a g-specific adenine glycosylase
BH370_RS19535	COG2226	methyltransferase
BH370_RS19545	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH370_RS19550	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH370_RS19565	COG1024	Enoyl-CoA hydratase
BH370_RS19585	COG1024	Enoyl-CoA hydratase
BH370_RS19590	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH370_RS19605	COG0753	catalase activity
BH370_RS19610	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BH370_RS19615	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BH370_RS19625	COG2175	clavaminate synthase activity
BH370_RS19630	COG1473	amidohydrolase
BH370_RS19635	COG4608	Belongs to the ABC transporter superfamily
BH370_RS19640	COG0444	Belongs to the ABC transporter superfamily
BH370_RS19655	COG0747	negative chemotaxis
BH370_RS19660	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BH370_RS19675	COG3850	Histidine kinase
BH370_RS19675	COG5002	protein histidine kinase activity
BH370_RS19695	COG0436	Aminotransferase
BH370_RS19700	COG1278	Cold shock
BH370_RS19845	COG1596	polysaccharide export
BH370_RS19845	COG1555	photosystem II stabilization
BH370_RS19960	COG0463	Glycosyl transferase, family 2
BH370_RS20030	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BH370_RS20075	COG3842	ATPase activity
BH370_RS20190	COG4172	Belongs to the ABC transporter superfamily
BH370_RS20240	COG0537	adenosine 5'-monophosphoramidase activity
BH370_RS20370	COG2333	competence protein COMEC
BH370_RS20370	COG0658	competence protein