locus-tag	class	description
Q425_RS00005	COG0445	tRNA wobble uridine modification
Q425_RS00010	COG0357	Ribosomal RNA small subunit methyltransferase G
Q425_RS00015	COG1192	Involved in chromosome partitioning
Q425_RS00025	COG1475	DNA binding
Q425_RS00030	COG0252	asparaginase activity
Q425_RS00055	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Q425_RS00065	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Q425_RS00075	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Q425_RS00080	COG0081	regulation of translation
Q425_RS00085	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Q425_RS00090	COG0222	ribosome binding
Q425_RS00095	COG0085	RNA polymerase activity
Q425_RS00100	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Q425_RS00140	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Q425_RS00165	COG1024	Enoyl-CoA hydratase
Q425_RS00185	COG0752	glycyl-tRNA synthetase alpha subunit
Q425_RS00190	COG0751	glycine-tRNA ligase activity
Q425_RS00195	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
Q425_RS00200	COG0204	Acyl-transferase
Q425_RS00215	COG0242	peptide deformylase activity
Q425_RS00250	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
Q425_RS00255	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Q425_RS00260	COG2813	Specifically methylates the guanine in position
Q425_RS00260	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Q425_RS00270	COG2223	nitrite transmembrane transporter activity
Q425_RS00275	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
Q425_RS00280	COG1794	racemase activity, acting on amino acids and derivatives
Q425_RS00285	COG1126	abc transporter atp-binding protein
Q425_RS00290	COG0765	amino acid transport
Q425_RS00295	COG0765	amino acid transport
Q425_RS00300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Q425_RS00355	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Q425_RS00380	COG0326	Molecular chaperone. Has ATPase activity
Q425_RS00385	COG0625	glutathione transferase activity
Q425_RS00400	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Q425_RS00405	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Q425_RS00415	COG0494	nUDIX hydrolase
Q425_RS00425	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
Q425_RS00435	COG0444	Belongs to the ABC transporter superfamily
Q425_RS00440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Q425_RS00445	COG0601	transmembrane transport
Q425_RS00450	COG0747	negative chemotaxis
Q425_RS00455	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Q425_RS00475	COG0697	spore germination
Q425_RS00485	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
Q425_RS00490	COG2948	multi-organism process
Q425_RS00495	COG3504	Conjugal transfer protein
Q425_RS00500	COG3736	Type IV secretory pathway, component VirB8
Q425_RS00515	COG3451	type IV secretory pathway VirB4
Q425_RS00520	COG3702	type iv secretory pathway
Q425_RS00555	COG3181	Tripartite tricarboxylate transporter family receptor
Q425_RS00570	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Q425_RS00575	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Q425_RS00580	COG0537	adenosine 5'-monophosphoramidase activity
Q425_RS00585	COG0140	phosphoribosyl-ATP diphosphatase activity
Q425_RS00590	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Q425_RS00595	COG0107	imidazoleglycerol-phosphate synthase activity
Q425_RS00600	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Q425_RS00605	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Q425_RS00610	COG0131	Imidazoleglycerol-phosphate dehydratase
Q425_RS00615	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Q425_RS00620	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Q425_RS00625	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Q425_RS00630	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Q425_RS00640	COG0842	Transport permease protein
Q425_RS00645	COG1131	(ABC) transporter
Q425_RS00655	COG2853	Lipoprotein
Q425_RS00660	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
Q425_RS00665	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Q425_RS00670	COG1127	ABC transporter
Q425_RS00680	COG3047	cAMP biosynthetic process
Q425_RS00690	COG0070	glutamate synthase
Q425_RS00690	COG0069	glutamate synthase activity
Q425_RS00690	COG0067	glutamate synthase
Q425_RS00700	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
Q425_RS00705	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
Q425_RS00715	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Q425_RS00720	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
Q425_RS00740	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Q425_RS00780	COG0109	protoheme IX farnesyltransferase activity
Q425_RS00785	COG1999	signal sequence binding
Q425_RS00805	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Q425_RS00810	COG2814	Major facilitator Superfamily
Q425_RS00900	COG2816	NAD+ diphosphatase activity
Q425_RS00905	COG1309	transcriptional regulator
Q425_RS00910	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Q425_RS00925	COG1024	Enoyl-CoA hydratase
Q425_RS00940	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Q425_RS00955	COG3181	Tripartite tricarboxylate transporter family receptor
Q425_RS00985	COG0438	transferase activity, transferring glycosyl groups
Q425_RS00990	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Q425_RS00995	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Q425_RS01025	COG0859	PFAM glycosyl transferase family 9
Q425_RS01040	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
Q425_RS01050	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Q425_RS01055	COG1127	ABC transporter
Q425_RS01085	COG1686	Belongs to the peptidase S11 family
Q425_RS01095	COG2921	Belongs to the UPF0250 family
Q425_RS01100	COG0321	lipoyl(octanoyl) transferase activity
Q425_RS01105	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Q425_RS01140	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Q425_RS01150	COG0018	arginyl-trna synthetase
Q425_RS01170	COG0395	ABC-type sugar transport system, permease component
Q425_RS01175	COG1175	transmembrane transport
Q425_RS01180	COG1653	transport
Q425_RS01185	COG3842	ATPase activity
Q425_RS01190	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
Q425_RS01200	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
Q425_RS01220	COG1609	Transcriptional regulator
Q425_RS01230	COG0154	amidase activity
Q425_RS01235	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Q425_RS01245	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
Q425_RS01255	COG0583	DNA-binding transcription factor activity
Q425_RS01270	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
Q425_RS01275	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Q425_RS01290	COG1802	Transcriptional regulator
Q425_RS01305	COG1024	Enoyl-CoA hydratase
Q425_RS01320	COG3181	Tripartite tricarboxylate transporter family receptor
Q425_RS01335	COG1984	allophanate hydrolase subunit 2
Q425_RS01340	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
Q425_RS01350	COG0583	DNA-binding transcription factor activity
Q425_RS01355	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Q425_RS01365	COG5002	protein histidine kinase activity
Q425_RS01375	COG5002	protein histidine kinase activity
Q425_RS01380	COG0745	RESPONSE REGULATOR receiver
Q425_RS01385	COG2226	methyltransferase
Q425_RS01400	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Q425_RS01420	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
Q425_RS01430	COG0513	Belongs to the DEAD box helicase family
Q425_RS01435	COG1280	lysine exporter protein (LysE YggA)
Q425_RS01440	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
Q425_RS01475	COG1054	Belongs to the UPF0176 family
Q425_RS01480	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Q425_RS01480	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Q425_RS01490	COG0489	protein tyrosine kinase activity
Q425_RS01505	COG0717	Belongs to the dCTP deaminase family
Q425_RS01535	COG2081	HI0933 family
Q425_RS01550	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
Q425_RS01560	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Q425_RS01565	COG0509	glycine decarboxylation via glycine cleavage system
Q425_RS01570	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Q425_RS01570	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Q425_RS01600	COG1960	acyl-CoA dehydrogenase activity
Q425_RS01630	COG1304	FMN binding
Q425_RS01645	COG0154	amidase activity
Q425_RS01650	COG1414	Transcriptional regulator
Q425_RS01665	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Q425_RS01670	COG0230	Belongs to the bacterial ribosomal protein bL34 family
Q425_RS01675	COG0594	ribonuclease P activity
Q425_RS01680	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
Q425_RS01685	COG0706	membrane insertase activity
Q425_RS01695	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
Q425_RS01720	COG0582	viral genome integration into host DNA
Q425_RS01755	COG3723	Recombinational DNA repair protein, rece pathway
Q425_RS01800	COG3181	Tripartite tricarboxylate transporter family receptor
Q425_RS01815	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Q425_RS01825	COG0411	ABC transporter
Q425_RS01830	COG0559	Belongs to the binding-protein-dependent transport system permease family
Q425_RS01835	COG0683	leucine binding
Q425_RS01855	COG0508	dehydrogenase complex catalyzes the overall conversion of
Q425_RS01860	COG1024	Enoyl-CoA hydratase
Q425_RS01865	COG0022	dehydrogenase e1 component
Q425_RS01870	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Q425_RS01890	COG1960	acyl-CoA dehydrogenase activity
Q425_RS01900	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Q425_RS01920	COG1960	acyl-CoA dehydrogenase activity
Q425_RS01925	COG3181	Tripartite tricarboxylate transporter family receptor
Q425_RS01930	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Q425_RS01940	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Q425_RS01965	COG3181	Tripartite tricarboxylate transporter family receptor
Q425_RS01975	COG0277	FAD linked oxidase domain protein
Q425_RS01980	COG1960	acyl-CoA dehydrogenase activity
Q425_RS01985	COG1960	acyl-CoA dehydrogenase activity
Q425_RS01995	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Q425_RS02010	COG2072	flavoprotein involved in K transport
Q425_RS02015	COG0604	alcohol dehydrogenase
Q425_RS02030	COG1024	Enoyl-CoA hydratase
Q425_RS02050	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Q425_RS02055	COG1522	sequence-specific DNA binding
Q425_RS02060	COG0183	Belongs to the thiolase family
Q425_RS02070	COG1960	acyl-CoA dehydrogenase activity
Q425_RS02110	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
Q425_RS02115	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Q425_RS02120	COG2890	protein-(glutamine-N5) methyltransferase activity
Q425_RS02125	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
Q425_RS02135	COG3181	Tripartite tricarboxylate transporter family receptor
Q425_RS02175	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
Q425_RS02180	COG1660	Displays ATPase and GTPase activities
Q425_RS02190	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Q425_RS02190	COG2010	Cytochrome c
Q425_RS02195	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
Q425_RS02205	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
Q425_RS02210	COG1137	ATPase activity
Q425_RS02225	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
Q425_RS02235	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
Q425_RS02270	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Q425_RS02275	COG3568	Endonuclease Exonuclease Phosphatase
Q425_RS02280	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Q425_RS02330	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
Q425_RS02335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Q425_RS02350	COG0823	Involved in the tonB-independent uptake of proteins
Q425_RS02360	COG0848	biopolymer transport protein
Q425_RS02365	COG0811	peptide transport
Q425_RS02370	COG0824	Thioesterase
Q425_RS02375	COG0442	prolyl-tRNA aminoacylation
Q425_RS02380	COG0494	nUDIX hydrolase
Q425_RS02395	COG2135	peptidase activity
Q425_RS02460	COG1196	nuclear chromosome segregation
Q425_RS02530	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
Q425_RS02535	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Q425_RS02540	COG0546	phosphoglycolate phosphatase activity
Q425_RS02550	COG1530	ribonuclease E activity
Q425_RS02565	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
Q425_RS02570	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
Q425_RS02575	COG0159	tryptophan synthase activity
Q425_RS02580	COG0133	tryptophan synthase activity
Q425_RS02590	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Q425_RS02595	COG3228	Belongs to the MtfA family
Q425_RS02605	COG0251	oxidation-reduction process
Q425_RS02610	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
Q425_RS02615	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
Q425_RS02630	COG2878	Part of a membrane complex involved in electron transport
Q425_RS02635	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Q425_RS02670	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Q425_RS02690	COG1268	BioY protein
Q425_RS02695	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
Q425_RS02700	COG1122	ATPase activity
Q425_RS02705	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Q425_RS02720	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Q425_RS02725	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Q425_RS02735	COG1196	nuclear chromosome segregation
Q425_RS02740	COG0477	Major facilitator Superfamily
Q425_RS02745	COG1573	uracil-dna glycosylase
Q425_RS02750	COG1214	PFAM Peptidase M22, glycoprotease
Q425_RS02770	COG0450	alkyl hydroperoxide reductase
Q425_RS02775	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Q425_RS02785	COG2223	nitrite transmembrane transporter activity
Q425_RS02795	COG2186	Transcriptional regulator
Q425_RS02815	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Q425_RS02825	COG0583	DNA-binding transcription factor activity
Q425_RS02835	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Q425_RS02840	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Q425_RS02845	COG0137	argininosuccinate synthase activity
Q425_RS02850	COG3158	transport of potassium into the cell
Q425_RS02855	COG0642	Histidine kinase
Q425_RS02885	COG0776	regulation of translation
Q425_RS02890	COG3128	pkhd-type hydroxylase
Q425_RS02900	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Q425_RS02905	COG0557	exoribonuclease II activity
Q425_RS02930	COG0679	Auxin Efflux Carrier
Q425_RS02935	COG2391	methyltransferase activity
Q425_RS02940	COG0069	glutamate synthase activity
Q425_RS02950	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Q425_RS02960	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
Q425_RS02965	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Q425_RS03000	COG3706	GGDEF domain
Q425_RS03015	COG1053	succinate dehydrogenase
Q425_RS03020	COG0583	DNA-binding transcription factor activity
Q425_RS03030	COG1053	succinate dehydrogenase
Q425_RS03050	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Q425_RS03055	COG0459	protein refolding
Q425_RS03060	COG3468	outer membrane autotransporter barrel domain protein
Q425_RS03075	COG1252	NADH dehydrogenase
Q425_RS03080	COG0284	orotidine-5'-phosphate decarboxylase activity
Q425_RS03085	COG1546	Belongs to the CinA family
Q425_RS03085	COG1058	Belongs to the CinA family
Q425_RS03090	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
Q425_RS03100	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Q425_RS03105	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Q425_RS03140	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
Q425_RS03145	COG3639	organic phosphonate transmembrane transporter activity
Q425_RS03150	COG3639	organic phosphonate transmembrane transporter activity
Q425_RS03170	COG0742	ribosomal rna small subunit methyltransferase
Q425_RS03175	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Q425_RS03180	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
Q425_RS03185	COG3135	benzoate transporter
Q425_RS03200	COG0640	Transcriptional regulator
Q425_RS03230	COG4172	Belongs to the ABC transporter superfamily
Q425_RS03235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Q425_RS03240	COG0601	transmembrane transport
Q425_RS03255	COG0281	malic enzyme
Q425_RS03255	COG0280	phosphate acetyltransferase
Q425_RS03315	COG0583	DNA-binding transcription factor activity
Q425_RS03325	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
Q425_RS03330	COG0167	dihydroorotate dehydrogenase activity
Q425_RS03350	COG1414	Transcriptional regulator
Q425_RS03355	COG1546	Belongs to the CinA family
Q425_RS03355	COG1058	Belongs to the CinA family
Q425_RS03375	COG0513	Belongs to the DEAD box helicase family
Q425_RS03405	COG0429	hydrolase of the alpha beta-hydrolase fold
Q425_RS03410	COG4783	chaperone-mediated protein folding
Q425_RS03425	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
Q425_RS03450	COG0006	proline dipeptidase activity
Q425_RS03460	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Q425_RS03480	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
Q425_RS03485	COG0632	four-way junction helicase activity
Q425_RS03500	COG2255	four-way junction helicase activity
Q425_RS03505	COG0514	ATP-dependent DNA helicase (RecQ)
Q425_RS03520	COG0288	reversible hydration of carbon dioxide
Q425_RS03525	COG0154	amidase activity
Q425_RS03535	COG4211	Belongs to the binding-protein-dependent transport system permease family
Q425_RS03565	COG1464	Belongs to the NlpA lipoprotein family
Q425_RS03655	COG0028	Belongs to the TPP enzyme family
Q425_RS03660	COG0440	acetolactate synthase activity
Q425_RS03665	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Q425_RS03670	COG1183	phosphatidylcholine synthase activity
Q425_RS03680	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Q425_RS03685	COG1185	polyribonucleotide nucleotidyltransferase activity
Q425_RS03700	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Q425_RS03720	COG0149	triose-phosphate isomerase activity
Q425_RS03725	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Q425_RS03735	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Q425_RS03745	COG3799	methylaspartate ammonia-lyase activity
Q425_RS03785	COG0583	DNA-binding transcription factor activity
Q425_RS03790	COG0626	cystathionine gamma-synthase activity
Q425_RS03795	COG3608	succinylglutamate desuccinylase aspartoacylase
Q425_RS03815	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Q425_RS03835	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
Q425_RS03855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Q425_RS03860	COG1733	regulation of RNA biosynthetic process
Q425_RS03870	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Q425_RS03875	COG0583	DNA-binding transcription factor activity
Q425_RS03880	COG1597	lipid kinase activity
Q425_RS03890	COG0671	phosphoesterase, PA-phosphatase related
Q425_RS03915	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
Q425_RS03920	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Q425_RS03925	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Q425_RS03930	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Q425_RS03935	COG0649	NAD binding
Q425_RS03940	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
Q425_RS03950	COG1034	ATP synthesis coupled electron transport
Q425_RS03955	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
Q425_RS03960	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Q425_RS03970	COG0713	ATP synthesis coupled electron transport
Q425_RS03985	COG1007	ATP synthesis coupled electron transport
Q425_RS03995	COG4774	siderophore transport
Q425_RS04000	COG4774	siderophore transport
Q425_RS04015	COG0028	Belongs to the TPP enzyme family
Q425_RS04020	COG3181	Tripartite tricarboxylate transporter family receptor
Q425_RS04025	COG0583	DNA-binding transcription factor activity
Q425_RS04030	COG0560	Phosphoserine phosphatase
Q425_RS04035	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Q425_RS04040	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Q425_RS04045	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Q425_RS04055	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
Q425_RS04060	COG0308	aminopeptidase N
Q425_RS04075	COG5265	(ABC) transporter
Q425_RS04080	COG0500	methyltransferase
Q425_RS04095	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
Q425_RS04125	COG0511	ligase activity, forming carbon-carbon bonds
Q425_RS04150	COG2188	Transcriptional regulator
Q425_RS04155	COG0439	Biotin carboxylase
Q425_RS04160	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Q425_RS04205	COG5265	(ABC) transporter
Q425_RS04215	COG0667	Aldo Keto reductase
Q425_RS04230	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Q425_RS04265	COG0583	DNA-binding transcription factor activity
Q425_RS04280	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Q425_RS04290	COG2079	MmgE PrpD family protein
Q425_RS04295	COG1012	belongs to the aldehyde dehydrogenase family
Q425_RS04300	COG1053	succinate dehydrogenase
Q425_RS04325	COG0179	Fumarylacetoacetate (FAA) hydrolase
Q425_RS04340	COG0583	DNA-binding transcription factor activity
Q425_RS04380	COG0583	DNA-binding transcription factor activity
Q425_RS04400	COG2814	Major facilitator Superfamily
Q425_RS04410	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Q425_RS04430	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
Q425_RS04440	COG0287	Prephenate dehydrogenase
Q425_RS04445	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Q425_RS04450	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
Q425_RS04470	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
Q425_RS04475	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
Q425_RS04480	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Q425_RS04500	COG2951	lytic endotransglycosylase activity
Q425_RS04505	COG0123	including yeast histone deacetylase and acetoin utilization protein
Q425_RS04520	COG1960	acyl-CoA dehydrogenase activity
Q425_RS04525	COG0450	alkyl hydroperoxide reductase
Q425_RS04540	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
Q425_RS04545	COG4208	sulfate ABC transporter
Q425_RS04550	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
Q425_RS04555	COG0175	sulfate reduction
Q425_RS04585	COG0335	large ribosomal subunit rRNA binding
Q425_RS04595	COG0667	Aldo Keto reductase
Q425_RS04605	COG2814	Major facilitator Superfamily
Q425_RS04610	COG3161	chorismate lyase activity
Q425_RS04615	COG1187	pseudouridine synthase activity
Q425_RS04625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Q425_RS04645	COG1999	signal sequence binding
Q425_RS04650	COG0339	signal peptide processing
Q425_RS04655	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Q425_RS04660	COG4566	intracellular signal transduction
Q425_RS04670	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
Q425_RS04675	COG0508	dehydrogenase complex catalyzes the overall conversion of
Q425_RS04680	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Q425_RS04685	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Q425_RS04695	COG1385	rRNA (uridine-N3-)-methyltransferase activity
Q425_RS04700	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
Q425_RS04705	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Q425_RS04710	COG0126	phosphoglycerate kinase activity
Q425_RS04715	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Q425_RS04720	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Q425_RS04735	COG0625	glutathione transferase activity
Q425_RS04765	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
Q425_RS04770	COG0306	phosphate transporter
Q425_RS04805	COG0745	RESPONSE REGULATOR receiver
Q425_RS04810	COG2198	Histidine kinase
Q425_RS04810	COG0643	Histidine kinase
Q425_RS04820	COG0840	transmembrane signaling receptor activity
Q425_RS04830	COG2201	protein-glutamate methylesterase activity
Q425_RS04835	COG0745	RESPONSE REGULATOR receiver
Q425_RS04840	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
Q425_RS04865	COG0667	Aldo Keto reductase
Q425_RS04875	COG4535	Mg2 and Co2 transporter CorC
Q425_RS04880	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Q425_RS04885	COG1702	phosphate starvation-inducible protein PhoH
Q425_RS04890	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Q425_RS04905	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Q425_RS04910	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Q425_RS04915	COG1862	Preprotein translocase
Q425_RS04920	COG0343	queuine tRNA-ribosyltransferase activity
Q425_RS04925	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
Q425_RS04930	COG2027	D-alanyl-D-alanine carboxypeptidase
Q425_RS04935	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
Q425_RS04945	COG3468	outer membrane autotransporter barrel domain protein
Q425_RS04950	COG1648	precorrin-2 dehydrogenase activity
Q425_RS04950	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Q425_RS04975	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
Q425_RS04980	COG0741	lytic transglycosylase activity
Q425_RS04985	COG0436	Aminotransferase
Q425_RS05005	COG2732	(Barnase) inhibitor
Q425_RS05020	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Q425_RS05045	COG0248	Ppx GppA phosphatase
Q425_RS05055	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Q425_RS05065	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Q425_RS05070	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
Q425_RS05075	COG1534	Rna-binding protein
Q425_RS05100	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Q425_RS05115	COG1295	ribonuclease BN
Q425_RS05130	COG0745	RESPONSE REGULATOR receiver
Q425_RS05135	COG2205	protein histidine kinase activity
Q425_RS05170	COG1022	Amp-dependent synthetase and ligase
Q425_RS05185	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Q425_RS05190	COG1028	Short-chain dehydrogenase reductase Sdr
Q425_RS05195	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
Q425_RS05200	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Q425_RS05215	COG1136	(ABC) transporter
Q425_RS05220	COG0084	hydrolase, TatD family'
Q425_RS05240	COG0658	competence protein
Q425_RS05240	COG2333	competence protein COMEC
Q425_RS05250	COG0613	PHP domain protein
Q425_RS05265	COG3539	Fimbrial protein
Q425_RS05270	COG0280	phosphate acetyltransferase
Q425_RS05270	COG0281	malic enzyme
Q425_RS05280	COG1522	sequence-specific DNA binding
Q425_RS05285	COG1297	OPT oligopeptide transporter protein
Q425_RS05290	COG1297	OPT oligopeptide transporter protein
Q425_RS05295	COG0567	Dehydrogenase, E1 component
Q425_RS05300	COG0508	dehydrogenase complex catalyzes the overall conversion of
Q425_RS05305	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Q425_RS05310	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
Q425_RS05315	COG1028	Short-chain dehydrogenase reductase Sdr
Q425_RS05320	COG0583	DNA-binding transcription factor activity
Q425_RS05330	COG3181	Tripartite tricarboxylate transporter family receptor
Q425_RS05355	COG1595	DNA-templated transcription, initiation
Q425_RS05360	COG3712	iron ion homeostasis
Q425_RS05365	COG4774	siderophore transport
Q425_RS05390	COG0180	Tryptophanyl-tRNA synthetase
Q425_RS05395	COG2183	response to ionizing radiation
Q425_RS05400	COG1199	ATP-dependent helicase activity
Q425_RS05410	COG0564	pseudouridine synthase activity
Q425_RS05420	COG3243	poly(R)-hydroxyalkanoic acid synthase
Q425_RS05425	COG1028	Short-chain dehydrogenase reductase Sdr
Q425_RS05430	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
Q425_RS05445	COG0672	)-iron permease
Q425_RS05485	COG0583	DNA-binding transcription factor activity
Q425_RS05495	COG2814	Major facilitator Superfamily
Q425_RS05510	COG1619	proteins homologs of microcin C7 resistance protein MccF
Q425_RS05525	COG2084	Dehydrogenase
Q425_RS05530	COG3181	Tripartite tricarboxylate transporter family receptor
Q425_RS05555	COG2988	succinylglutamate desuccinylase activity
Q425_RS05585	COG0765	amino acid transport
Q425_RS05590	COG0765	amino acid transport
Q425_RS05595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Q425_RS05630	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Q425_RS05635	COG1595	DNA-templated transcription, initiation
Q425_RS05645	COG3530	Putative quorum-sensing-regulated virulence factor
Q425_RS05650	COG0494	nUDIX hydrolase
Q425_RS05665	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Q425_RS05670	COG0542	response to heat
Q425_RS05685	COG0165	Argininosuccinate lyase
Q425_RS05690	COG0668	transmembrane transport
Q425_RS05735	COG0747	negative chemotaxis
Q425_RS05740	COG0601	transmembrane transport
Q425_RS05745	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Q425_RS05750	COG1162	GTPase activity
Q425_RS05755	COG0501	Belongs to the peptidase M48B family
Q425_RS05760	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
Q425_RS05770	COG3327	negative regulation of DNA-templated transcription, initiation
Q425_RS05775	COG3396	Phenylacetate-CoA oxygenase
Q425_RS05780	COG3460	Phenylacetate-CoA oxygenase
Q425_RS05785	COG3396	Phenylacetate-CoA oxygenase
Q425_RS05790	COG2151	metal-sulfur cluster biosynthetic enzyme
Q425_RS05795	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Q425_RS05805	COG1012	belongs to the aldehyde dehydrogenase family
Q425_RS05810	COG1024	Enoyl-CoA hydratase
Q425_RS05815	COG2050	protein possibly involved in aromatic compounds catabolism
Q425_RS05825	COG3539	Fimbrial protein
Q425_RS05835	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Q425_RS05840	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
Q425_RS05840	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Q425_RS05845	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
Q425_RS05850	COG0047	phosphoribosylformylglycinamidine synthase activity
Q425_RS05850	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Q425_RS05855	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
Q425_RS05855	COG3064	Membrane
Q425_RS05855	COG3210	domain, Protein
Q425_RS05880	COG0235	Class ii aldolase
Q425_RS05885	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
Q425_RS05890	COG0720	synthase
Q425_RS05895	COG0602	queuosine metabolic process
Q425_RS05920	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Q425_RS05955	COG3181	Tripartite tricarboxylate transporter family receptor
Q425_RS05985	COG3842	ATPase activity
Q425_RS05995	COG0395	ABC-type sugar transport system, permease component
Q425_RS06025	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Q425_RS06030	COG0420	3'-5' exonuclease activity
Q425_RS06055	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Q425_RS06060	COG3568	Endonuclease Exonuclease Phosphatase
Q425_RS06065	COG1695	Transcriptional regulator
Q425_RS06085	COG0583	DNA-binding transcription factor activity
Q425_RS06100	COG1802	Transcriptional regulator
Q425_RS06110	COG3181	Tripartite tricarboxylate transporter family receptor
Q425_RS06120	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Q425_RS06135	COG0066	3-isopropylmalate dehydratase activity
Q425_RS06145	COG3181	Tripartite tricarboxylate transporter family receptor
Q425_RS06150	COG4948	Mandelate Racemase Muconate Lactonizing
Q425_RS06165	COG1126	abc transporter atp-binding protein
Q425_RS06170	COG0765	amino acid transport
Q425_RS06175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Q425_RS06215	COG1815	bacterial-type flagellum-dependent cell motility
Q425_RS06220	COG1558	bacterial-type flagellum-dependent cell motility
Q425_RS06230	COG1749	Flagellar hook protein flgE
Q425_RS06245	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
Q425_RS06250	COG1706	bacterial-type flagellum-dependent cell motility
Q425_RS06260	COG1256	bacterial-type flagellum assembly
Q425_RS06270	COG0840	transmembrane signaling receptor activity
Q425_RS06275	COG0840	transmembrane signaling receptor activity
Q425_RS06280	COG0840	transmembrane signaling receptor activity
Q425_RS06300	COG1338	Plays a role in the flagellum-specific transport system
Q425_RS06320	COG1580	Controls the rotational direction of flagella during chemotaxis
Q425_RS06350	COG1157	protein secretion by the type III secretion system
Q425_RS06355	COG1317	bacterial-type flagellum organization
Q425_RS06360	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Q425_RS06370	COG1677	Flagellar hook-basal body complex protein FliE
Q425_RS06380	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Q425_RS06415	COG0285	dihydrofolate synthase activity
Q425_RS06445	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
Q425_RS06450	COG0024	Methionine aminopeptidase
Q425_RS06455	COG0052	Belongs to the universal ribosomal protein uS2 family
Q425_RS06460	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Q425_RS06465	COG0528	UMP kinase activity
Q425_RS06470	COG0233	cytoplasmic translational termination
Q425_RS06475	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Q425_RS06485	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
Q425_RS06490	COG0750	zinc metalloprotease
Q425_RS06495	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Q425_RS06500	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
Q425_RS06505	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Q425_RS06510	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Q425_RS06520	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Q425_RS06525	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Q425_RS06530	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Q425_RS06535	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
Q425_RS06545	COG0519	Catalyzes the synthesis of GMP from XMP
Q425_RS06545	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Q425_RS06560	COG0330	HflC and HflK could
Q425_RS06565	COG3706	GGDEF domain
Q425_RS06570	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Q425_RS06575	COG2867	negative regulation of translational initiation
Q425_RS06585	COG1960	acyl-CoA dehydrogenase activity
Q425_RS06590	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
Q425_RS06620	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Q425_RS06625	COG0505	Belongs to the CarA family
Q425_RS06630	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Q425_RS06640	COG0406	alpha-ribazole phosphatase activity
Q425_RS06650	COG3842	ATPase activity
Q425_RS06670	COG5001	Diguanylate cyclase
Q425_RS06675	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Q425_RS06685	COG1763	Mo-molybdopterin cofactor biosynthetic process
Q425_RS06690	COG0303	'Molybdopterin
Q425_RS06695	COG0746	molybdenum cofactor guanylyltransferase activity
Q425_RS06700	COG0489	protein tyrosine kinase activity
Q425_RS06730	COG0243	molybdopterin cofactor binding
Q425_RS06730	COG3383	formate dehydrogenase (NAD+) activity
Q425_RS06735	COG0437	4 iron, 4 sulfur cluster binding
Q425_RS06765	COG1122	ATPase activity
Q425_RS06775	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Q425_RS06780	COG0066	3-isopropylmalate dehydratase activity
Q425_RS06785	COG0473	3-isopropylmalate dehydrogenase activity
Q425_RS06790	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Q425_RS06800	COG0101	tRNA pseudouridine synthase activity
Q425_RS06805	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
Q425_RS06820	COG0135	phosphoribosylanthranilate isomerase activity
Q425_RS06845	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Q425_RS06855	COG2197	response regulator
Q425_RS06860	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Q425_RS06865	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
Q425_RS06870	COG0189	ligase activity
Q425_RS06880	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Q425_RS06885	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Q425_RS06895	COG2423	ornithine cyclodeaminase activity
Q425_RS06905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Q425_RS06910	COG0765	amino acid transport
Q425_RS06915	COG0765	amino acid transport
Q425_RS06920	COG1126	abc transporter atp-binding protein
Q425_RS06975	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Q425_RS06985	COG2944	sequence-specific DNA binding
Q425_RS06990	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
Q425_RS06995	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
Q425_RS07000	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
Q425_RS07005	COG0009	L-threonylcarbamoyladenylate synthase
Q425_RS07010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Q425_RS07015	COG1414	Transcriptional regulator
Q425_RS07030	COG0765	amino acid transport
Q425_RS07035	COG1126	abc transporter atp-binding protein
Q425_RS07040	COG0028	Belongs to the TPP enzyme family
Q425_RS07055	COG0028	Belongs to the TPP enzyme family
Q425_RS07060	COG0583	DNA-binding transcription factor activity
Q425_RS07065	COG4974	Belongs to the 'phage' integrase family
Q425_RS07070	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
Q425_RS07075	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
Q425_RS07085	COG1686	Belongs to the peptidase S11 family
Q425_RS07095	COG2814	Major facilitator Superfamily
Q425_RS07105	COG1074	ATP-dependent DNA helicase activity
Q425_RS07110	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Q425_RS07115	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
Q425_RS07120	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Q425_RS07145	COG2321	neutral zinc metallopeptidase
Q425_RS07150	COG0009	L-threonylcarbamoyladenylate synthase
Q425_RS07160	COG1994	Peptidase M50
Q425_RS07165	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Q425_RS07170	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
Q425_RS07175	COG3539	Fimbrial protein
Q425_RS07180	COG2850	peptidyl-arginine hydroxylation
Q425_RS07185	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Q425_RS07190	COG3360	Dodecin
Q425_RS07230	COG0668	transmembrane transport
Q425_RS07250	COG0483	inositol monophosphate 1-phosphatase activity
Q425_RS07255	COG1253	flavin adenine dinucleotide binding
Q425_RS07260	COG1968	undecaprenyl-diphosphatase activity
Q425_RS07265	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Q425_RS07280	COG0215	cysteine-tRNA ligase activity
Q425_RS07290	COG0825	malonyl-CoA metabolic process
Q425_RS07300	COG0037	tRNA processing
Q425_RS07305	COG0527	aspartate kinase activity
Q425_RS07330	COG1250	3-hydroxyacyl-CoA dehydrogenase
Q425_RS07335	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
Q425_RS07335	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Q425_RS07350	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Q425_RS07355	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
Q425_RS07360	COG1028	Short-chain dehydrogenase reductase Sdr
Q425_RS07370	COG0583	DNA-binding transcription factor activity
Q425_RS07400	COG3842	ATPase activity
Q425_RS07410	COG0446	pyridine nucleotide-disulphide oxidoreductase
Q425_RS07410	COG1902	pentaerythritol trinitrate reductase activity
Q425_RS07415	COG1414	Transcriptional regulator
Q425_RS07420	COG1832	CoA-binding protein
Q425_RS07430	COG0251	oxidation-reduction process
Q425_RS07455	COG1902	pentaerythritol trinitrate reductase activity
Q425_RS07465	COG1215	transferase activity, transferring glycosyl groups
Q425_RS07470	COG1649	PFAM Uncharacterised BCR, COG1649
Q425_RS07470	COG0726	polysaccharide deacetylase
Q425_RS07490	COG1846	Transcriptional regulator
Q425_RS07520	COG2010	Cytochrome c
Q425_RS07520	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Q425_RS07525	COG2080	2 iron, 2 sulfur cluster binding
Q425_RS07530	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Q425_RS07535	COG3473	Maleate cis-trans isomerase
Q425_RS07545	COG2309	aminopeptidase activity
Q425_RS07550	COG1335	isochorismatase
Q425_RS07565	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Q425_RS07565	COG1017	nitric oxide dioxygenase activity
Q425_RS07580	COG3181	Tripartite tricarboxylate transporter family receptor
Q425_RS07595	COG0318	PFAM AMP-dependent synthetase and ligase
Q425_RS07605	COG0318	PFAM AMP-dependent synthetase and ligase
Q425_RS07615	COG0183	Belongs to the thiolase family
Q425_RS07620	COG1250	3-hydroxyacyl-CoA dehydrogenase
Q425_RS07620	COG1024	Enoyl-CoA hydratase
Q425_RS07635	COG0183	Belongs to the thiolase family
Q425_RS07650	COG2197	response regulator
Q425_RS07665	COG0166	Belongs to the GPI family
Q425_RS07670	COG1045	serine acetyltransferase
Q425_RS07680	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
Q425_RS07685	COG0483	inositol monophosphate 1-phosphatase activity
Q425_RS07690	COG1012	belongs to the aldehyde dehydrogenase family
Q425_RS07695	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Q425_RS07710	COG0210	DNA helicase
Q425_RS07715	COG0598	Magnesium transport protein CorA
Q425_RS07725	COG0747	negative chemotaxis
Q425_RS07730	COG0601	transmembrane transport
Q425_RS07735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Q425_RS07740	COG4172	Belongs to the ABC transporter superfamily
Q425_RS07745	COG1846	Transcriptional regulator
Q425_RS07790	COG4964	Belongs to the GSP D family
Q425_RS07830	COG2204	response regulator
Q425_RS07845	COG1595	DNA-templated transcription, initiation
Q425_RS07855	COG3474	cytochrome
Q425_RS07860	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Q425_RS07875	COG3384	dioxygenase
Q425_RS07880	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
Q425_RS07905	COG2885	chlorophyll binding
Q425_RS07940	COG0697	spore germination
Q425_RS07945	COG0730	response to heat
Q425_RS07960	COG0583	DNA-binding transcription factor activity
Q425_RS07965	COG0427	acetyl-CoA hydrolase
Q425_RS08010	COG3468	outer membrane autotransporter barrel domain protein
Q425_RS08015	COG0424	maF-like protein
Q425_RS08020	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
Q425_RS08025	COG0799	negative regulation of ribosome biogenesis
Q425_RS08030	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Q425_RS08035	COG0408	coproporphyrinogen oxidase activity
Q425_RS08040	COG0151	Belongs to the GarS family
Q425_RS08045	COG0217	transcriptional regulatory protein
Q425_RS08050	COG0433	COG0433 Predicted ATPase
Q425_RS08055	COG1115	amino acid carrier protein
Q425_RS08060	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Q425_RS08070	COG1012	belongs to the aldehyde dehydrogenase family
Q425_RS08095	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Q425_RS08110	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Q425_RS08120	COG0747	negative chemotaxis
Q425_RS08130	COG0473	3-isopropylmalate dehydrogenase activity
Q425_RS08135	COG2814	Major facilitator Superfamily
Q425_RS08140	COG1566	PFAM secretion protein HlyD family protein
Q425_RS08150	COG1846	Transcriptional regulator
Q425_RS08160	COG0697	spore germination
Q425_RS08170	COG0501	Belongs to the peptidase M48B family
Q425_RS08190	COG0583	DNA-binding transcription factor activity
Q425_RS08195	COG3842	ATPase activity
Q425_RS08200	COG1178	ABC-type Fe3 transport system permease component
Q425_RS08205	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Q425_RS08210	COG1840	ABC-type Fe3 transport system, periplasmic component
Q425_RS08215	COG0492	ferredoxin-NADP+ reductase activity
Q425_RS08235	COG2233	PERMEase
Q425_RS08240	COG0840	transmembrane signaling receptor activity
Q425_RS08245	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Q425_RS08275	COG4789	Type iii secretion
Q425_RS08340	COG4669	(LipO)protein
Q425_RS08375	COG4790	Type iii secretion
Q425_RS08380	COG4794	Type iii secretion
Q425_RS08385	COG4791	protein targeting
Q425_RS08390	COG4792	protein secretion
Q425_RS08405	COG1595	DNA-templated transcription, initiation
Q425_RS08430	COG2770	Histidine kinase
Q425_RS08430	COG2208	phosphoserine phosphatase activity
Q425_RS08440	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Q425_RS08445	COG2172	sigma factor antagonist activity
Q425_RS08450	COG1366	Belongs to the anti-sigma-factor antagonist family
Q425_RS08455	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Q425_RS08485	COG2358	TRAP transporter, solute receptor (TAXI family
Q425_RS08490	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Q425_RS08520	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Q425_RS08520	COG1017	nitric oxide dioxygenase activity
Q425_RS08525	COG1959	2 iron, 2 sulfur cluster binding
Q425_RS08530	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Q425_RS08550	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
Q425_RS08555	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
Q425_RS08560	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Q425_RS08565	COG0084	hydrolase, TatD family'
Q425_RS08580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Q425_RS08590	COG1126	abc transporter atp-binding protein
Q425_RS08595	COG0010	Belongs to the arginase family
Q425_RS08600	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Q425_RS08605	COG1012	belongs to the aldehyde dehydrogenase family
Q425_RS08615	COG0028	Belongs to the TPP enzyme family
Q425_RS08625	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
Q425_RS08625	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Q425_RS08635	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Q425_RS08650	COG3189	MarR family transcriptional regulator
Q425_RS08675	COG4336	lyase activity
Q425_RS08685	COG2205	protein histidine kinase activity
Q425_RS08685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Q425_RS08690	COG2197	response regulator
Q425_RS08695	COG3064	Membrane
Q425_RS08695	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
Q425_RS08695	COG3210	domain, Protein
Q425_RS08705	COG3121	Chaperone
Q425_RS08710	COG3188	usher protein
Q425_RS08715	COG3539	Fimbrial protein
Q425_RS08720	COG2831	hemolysin activation secretion protein
Q425_RS08735	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Q425_RS08760	COG0583	DNA-binding transcription factor activity
Q425_RS08785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Q425_RS08790	COG0765	amino acid transport
Q425_RS08795	COG1126	abc transporter atp-binding protein
Q425_RS08800	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Q425_RS08805	COG1758	RNA polymerase activity
Q425_RS08810	COG0194	GDP metabolic process
Q425_RS08815	COG3258	Cytochrome c
Q425_RS08820	COG2863	cytochrome
Q425_RS08825	COG1028	Short-chain dehydrogenase reductase Sdr
Q425_RS08830	COG0791	NLP P60 protein
Q425_RS08835	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Q425_RS08855	COG1561	YicC-like family, N-terminal region
Q425_RS08860	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
Q425_RS08880	COG2200	EAL domain
Q425_RS08880	COG2199	diguanylate cyclase activity
Q425_RS08885	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Q425_RS08895	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Q425_RS08900	COG0174	glutamine synthetase
Q425_RS08910	COG2204	response regulator
Q425_RS08915	COG0583	DNA-binding transcription factor activity
Q425_RS08920	COG1741	Belongs to the pirin family
Q425_RS08925	COG1741	Belongs to the pirin family
Q425_RS08930	COG3842	ATPase activity
Q425_RS08935	COG1178	ABC-type Fe3 transport system permease component
Q425_RS08940	COG1840	ABC-type Fe3 transport system, periplasmic component
Q425_RS08950	COG0583	DNA-binding transcription factor activity
Q425_RS08960	COG0656	L-ascorbic acid biosynthetic process
Q425_RS08975	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Q425_RS08980	COG0583	DNA-binding transcription factor activity
Q425_RS08995	COG0783	Belongs to the Dps family
Q425_RS09030	COG0438	transferase activity, transferring glycosyl groups
Q425_RS09045	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
Q425_RS09065	COG0300	oxidoreductase activity
Q425_RS09110	COG0861	Integral membrane protein TerC family
Q425_RS09115	COG1028	Short-chain dehydrogenase reductase Sdr
Q425_RS09135	COG0714	Associated with various cellular activities
Q425_RS09165	COG3119	arylsulfatase activity
Q425_RS09190	COG2197	response regulator
Q425_RS09200	COG2944	sequence-specific DNA binding
Q425_RS09205	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
Q425_RS09210	COG0625	glutathione transferase activity
Q425_RS09240	COG0179	Fumarylacetoacetate (FAA) hydrolase
Q425_RS09245	COG1028	Short-chain dehydrogenase reductase Sdr
Q425_RS09290	COG0431	NADPH-dependent FMN reductase
Q425_RS09320	COG1028	Short-chain dehydrogenase reductase Sdr
Q425_RS09325	COG0583	DNA-binding transcription factor activity
Q425_RS09340	COG3181	Tripartite tricarboxylate transporter family receptor
Q425_RS09345	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Q425_RS09345	COG2111	Na H antiporter
Q425_RS09350	COG1006	Multisubunit Na H antiporter MnhC subunit
Q425_RS09355	COG0651	ATP synthesis coupled electron transport
Q425_RS09360	COG1863	multisubunit Na H antiporter MnhE subunit
Q425_RS09365	COG2212	antiporter activity
Q425_RS09395	COG0590	tRNA wobble adenosine to inosine editing
Q425_RS09400	COG1619	proteins homologs of microcin C7 resistance protein MccF
Q425_RS09405	COG1024	Enoyl-CoA hydratase
Q425_RS09420	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
Q425_RS09425	COG0488	(ABC) transporter
Q425_RS09460	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Q425_RS09470	COG2252	PERMEase
Q425_RS09475	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Q425_RS09485	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
Q425_RS09490	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
Q425_RS09520	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Q425_RS09525	COG0789	Transcriptional regulator
Q425_RS09535	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
Q425_RS09535	COG0678	peroxiredoxin activity
Q425_RS09545	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
Q425_RS09550	COG0584	glycerophosphoryl diester phosphodiesterase
Q425_RS09555	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Q425_RS09565	COG4181	ATPase activity
Q425_RS09575	COG2823	Periplasmic or secreted lipoprotein
Q425_RS09585	COG3237	CsbD-like
Q425_RS09590	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Q425_RS09590	COG1181	Belongs to the D-alanine--D-alanine ligase family
Q425_RS09595	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Q425_RS09595	COG0189	ligase activity
Q425_RS09615	COG2833	Protein of unknown function (DUF455)
Q425_RS09620	COG2951	lytic endotransglycosylase activity
Q425_RS09635	COG1522	sequence-specific DNA binding
Q425_RS09645	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Q425_RS09650	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Q425_RS09655	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Q425_RS09660	COG0196	riboflavin kinase activity
Q425_RS09665	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Q425_RS09665	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Q425_RS09685	COG0210	DNA helicase
Q425_RS09690	COG4771	TonB-dependent receptor
Q425_RS09695	COG0488	(ABC) transporter
Q425_RS09700	COG2890	protein-(glutamine-N5) methyltransferase activity
Q425_RS09705	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Q425_RS09710	COG2171	N-acyltransferase activity
Q425_RS09745	COG1278	Cold shock
Q425_RS09755	COG1278	Cold shock
Q425_RS09765	COG0544	peptidyl-prolyl cis-trans isomerase activity
Q425_RS09770	COG0740	serine-type endopeptidase activity
Q425_RS09775	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Q425_RS09780	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Q425_RS09785	COG0583	DNA-binding transcription factor activity
Q425_RS09790	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Q425_RS09815	COG0183	Belongs to the thiolase family
Q425_RS09820	COG1028	Short-chain dehydrogenase reductase Sdr
Q425_RS09825	COG1960	acyl-CoA dehydrogenase activity
Q425_RS09840	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
Q425_RS09865	COG3468	outer membrane autotransporter barrel domain protein
Q425_RS09870	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Q425_RS09880	COG0556	nucleotide-excision repair
Q425_RS09885	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Q425_RS09895	COG1104	cysteine desulfurase activity
Q425_RS09900	COG0822	iron-sulfur transferase activity
Q425_RS09905	COG0316	Belongs to the HesB IscA family
Q425_RS09910	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
Q425_RS09915	COG0443	Heat shock 70 kDa protein
Q425_RS09920	COG0633	Ferredoxin
Q425_RS09940	COG1024	Enoyl-CoA hydratase
Q425_RS09960	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Q425_RS09960	COG0519	Catalyzes the synthesis of GMP from XMP
Q425_RS09970	COG3550	peptidyl-serine autophosphorylation
Q425_RS09980	COG0477	Major facilitator Superfamily
Q425_RS09995	COG1228	amidohydrolase
Q425_RS10005	COG1116	anion transmembrane transporter activity
Q425_RS10010	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Q425_RS10035	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Q425_RS10050	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
Q425_RS10080	COG2814	Major facilitator Superfamily
Q425_RS10095	COG1280	lysine exporter protein (LysE YggA)
Q425_RS10115	COG0747	negative chemotaxis
Q425_RS10120	COG0601	transmembrane transport
Q425_RS10125	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Q425_RS10130	COG4172	Belongs to the ABC transporter superfamily
Q425_RS10135	COG1609	Transcriptional regulator
Q425_RS10160	COG0586	Pfam SNARE associated Golgi protein
Q425_RS10170	COG0500	methyltransferase
Q425_RS10180	COG0756	dUTP diphosphatase activity
Q425_RS10190	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Q425_RS10210	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Q425_RS10215	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Q425_RS10220	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Q425_RS10225	COG0072	phenylalanine-tRNA ligase activity
Q425_RS10225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Q425_RS10230	COG0776	regulation of translation
Q425_RS10300	COG0540	Belongs to the ATCase OTCase family
Q425_RS10305	COG2974	May be involved in recombination
Q425_RS10315	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Q425_RS10320	COG0583	DNA-binding transcription factor activity
Q425_RS10340	COG1028	Short-chain dehydrogenase reductase Sdr
Q425_RS10355	COG3842	ATPase activity
Q425_RS10360	COG1024	Enoyl-CoA hydratase
Q425_RS10360	COG1250	3-hydroxyacyl-CoA dehydrogenase
Q425_RS10380	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Q425_RS10385	COG2137	regulation of response to DNA damage stimulus
Q425_RS10395	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
Q425_RS10405	COG0045	succinate-CoA ligase (ADP-forming) activity
Q425_RS10410	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
Q425_RS10415	COG0861	Integral membrane protein TerC family
Q425_RS10420	COG0861	Integral membrane protein TerC family
Q425_RS10430	COG0181	hydroxymethylbilane synthase activity
Q425_RS10490	COG4964	Belongs to the GSP D family
Q425_RS10520	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Q425_RS10530	COG0583	DNA-binding transcription factor activity
Q425_RS10540	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Q425_RS10545	COG4311	Sarcosine oxidase, delta subunit
Q425_RS10550	COG0446	pyridine nucleotide-disulphide oxidoreductase
Q425_RS10550	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Q425_RS10585	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Q425_RS10590	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Q425_RS10595	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Q425_RS10600	COG0735	belongs to the Fur family
Q425_RS10605	COG0497	DNA recombination
Q425_RS10610	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Q425_RS10615	COG1420	regulation of RNA biosynthetic process
Q425_RS10620	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Q425_RS10630	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Q425_RS10640	COG0443	Heat shock 70 kDa protein
Q425_RS10650	COG0612	Peptidase, M16
Q425_RS10670	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Q425_RS10715	COG0745	RESPONSE REGULATOR receiver
Q425_RS10720	COG2205	protein histidine kinase activity
Q425_RS10725	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
Q425_RS10730	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
Q425_RS10735	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
Q425_RS10745	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Q425_RS10760	COG1193	negative regulation of DNA recombination
Q425_RS10765	COG0492	ferredoxin-NADP+ reductase activity
Q425_RS10770	COG1674	ftsk spoiiie
Q425_RS10775	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
Q425_RS10780	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Q425_RS10785	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Q425_RS10810	COG3706	GGDEF domain
Q425_RS10830	COG2814	Major facilitator Superfamily
Q425_RS10860	COG3486	L-lysine 6-monooxygenase (NADPH) activity
Q425_RS10875	COG1028	Short-chain dehydrogenase reductase Sdr
Q425_RS10890	COG3022	response to hydroperoxide
Q425_RS10910	COG3023	N-Acetylmuramoyl-L-alanine amidase
Q425_RS10920	COG0424	maF-like protein
Q425_RS10925	COG1399	metal-binding, possibly nucleic acid-binding protein
Q425_RS10930	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Q425_RS10935	COG0416	fatty acid biosynthetic process
Q425_RS10940	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Q425_RS10955	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Q425_RS10960	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Q425_RS10985	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Q425_RS10990	COG0481	GTPase activity
Q425_RS10995	COG0681	Belongs to the peptidase S26 family
Q425_RS11000	COG0571	ribonuclease III activity
Q425_RS11005	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
Q425_RS11010	COG1381	Involved in DNA repair and RecF pathway recombination
Q425_RS11020	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Q425_RS11035	COG3181	Tripartite tricarboxylate transporter family receptor
Q425_RS11040	COG0670	Belongs to the BI1 family
Q425_RS11055	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Q425_RS11065	COG0583	DNA-binding transcription factor activity
Q425_RS11080	COG0583	DNA-binding transcription factor activity
Q425_RS11095	COG0791	NLP P60 protein
Q425_RS11100	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Q425_RS11105	COG3193	protein, possibly involved in utilization of glycolate and propanediol
Q425_RS11115	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Q425_RS11120	COG0697	spore germination
Q425_RS11125	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
Q425_RS11140	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Q425_RS11170	COG1446	asparaginase
Q425_RS11175	COG4172	Belongs to the ABC transporter superfamily
Q425_RS11180	COG0747	negative chemotaxis
Q425_RS11190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Q425_RS11215	COG0504	CTP synthase activity
Q425_RS11220	COG2877	3-deoxy-8-phosphooctulonate synthase activity
Q425_RS11230	COG0148	phosphopyruvate hydratase activity
Q425_RS11235	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
Q425_RS11265	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
Q425_RS11275	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Q425_RS11300	COG1981	membrane
Q425_RS11330	COG0039	L-malate dehydrogenase activity
Q425_RS11335	COG2188	Transcriptional regulator
Q425_RS11340	COG2009	succinate dehydrogenase
Q425_RS11345	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
Q425_RS11350	COG1053	succinate dehydrogenase
Q425_RS11355	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Q425_RS11360	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
Q425_RS11365	COG0372	Belongs to the citrate synthase family
Q425_RS11385	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
Q425_RS11385	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Q425_RS11395	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Q425_RS11400	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
Q425_RS11415	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
Q425_RS11420	COG3842	ATPase activity
Q425_RS11425	COG1176	ABC-type spermidine putrescine transport system, permease component I
Q425_RS11430	COG1177	transmembrane transport
Q425_RS11455	COG1960	acyl-CoA dehydrogenase activity
Q425_RS11460	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
Q425_RS11465	COG0704	Plays a role in the regulation of phosphate uptake
Q425_RS11475	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
Q425_RS11480	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Q425_RS11480	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
Q425_RS11485	COG1643	Atp-dependent helicase
Q425_RS11500	COG0438	transferase activity, transferring glycosyl groups
Q425_RS11505	COG0726	polysaccharide deacetylase
Q425_RS11510	COG0463	Glycosyl transferase, family 2
Q425_RS11515	COG0438	transferase activity, transferring glycosyl groups
Q425_RS11520	COG2194	sulfuric ester hydrolase activity
Q425_RS11545	COG0859	PFAM glycosyl transferase family 9
Q425_RS11550	COG1132	(ABC) transporter
Q425_RS11565	COG0077	Prephenate dehydratase
Q425_RS11570	COG1530	ribonuclease E activity
Q425_RS11615	COG1473	amidohydrolase
Q425_RS11620	COG0418	dihydroorotase activity
Q425_RS11625	COG0488	(ABC) transporter
Q425_RS11630	COG2001	Belongs to the MraZ family
Q425_RS11635	COG0275	rRNA processing
Q425_RS11640	COG3116	cell division
Q425_RS11650	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Q425_RS11655	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Q425_RS11660	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Q425_RS11670	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Q425_RS11675	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Q425_RS11680	COG1181	Belongs to the D-alanine--D-alanine ligase family
Q425_RS11685	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
Q425_RS11695	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Q425_RS11700	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
Q425_RS11710	COG0739	heme binding
Q425_RS11715	COG0653	protein targeting
Q425_RS11735	COG1028	Short-chain dehydrogenase reductase Sdr
Q425_RS11740	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Q425_RS11745	COG1522	sequence-specific DNA binding
Q425_RS11770	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Q425_RS11780	COG0557	exoribonuclease II activity
Q425_RS11785	COG3150	esterase
Q425_RS11790	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Q425_RS11795	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Q425_RS11800	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
Q425_RS11805	COG0511	ligase activity, forming carbon-carbon bonds
Q425_RS11810	COG0439	Biotin carboxylase
Q425_RS11815	COG2264	protein methyltransferase activity
Q425_RS11825	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Q425_RS11855	COG1696	Membrane protein involved in D-alanine export
Q425_RS11860	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Q425_RS11895	COG1522	sequence-specific DNA binding
Q425_RS11910	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Q425_RS11915	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Q425_RS11915	COG1042	CoA-binding domain protein
Q425_RS11915	COG0045	succinate-CoA ligase (ADP-forming) activity
Q425_RS11925	COG1802	Transcriptional regulator
Q425_RS11930	COG3069	C4-dicarboxylate transmembrane transporter activity
Q425_RS11935	COG0513	Belongs to the DEAD box helicase family
Q425_RS11940	COG0346	lactoylglutathione lyase activity
Q425_RS11945	COG1335	isochorismatase
Q425_RS11950	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Q425_RS11955	COG1116	anion transmembrane transporter activity
Q425_RS11970	COG3028	Belongs to the UPF0307 family
Q425_RS11975	COG0312	modulator of DNA gyrase
Q425_RS11980	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
Q425_RS11985	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Q425_RS11990	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Q425_RS11995	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Q425_RS12005	COG0316	Belongs to the HesB IscA family
Q425_RS12010	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
Q425_RS12025	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Q425_RS12035	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Q425_RS12040	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Q425_RS12055	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Q425_RS12055	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Q425_RS12090	COG0583	DNA-binding transcription factor activity
Q425_RS12095	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Q425_RS12130	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
Q425_RS12140	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Q425_RS12145	COG1845	cytochrome c oxidase, subunit III
Q425_RS12150	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
Q425_RS12155	COG0640	Transcriptional regulator
Q425_RS12175	COG3220	belongs to the UPF0276 family
Q425_RS12220	COG1666	GTP binding
Q425_RS12255	COG0312	modulator of DNA gyrase
Q425_RS12260	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Q425_RS12265	COG3210	domain, Protein
Q425_RS12265	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
Q425_RS12265	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
Q425_RS12265	COG3210	domain, Protein
Q425_RS12265	COG3064	Membrane
Q425_RS12265	COG3064	Membrane
Q425_RS12270	COG0277	FAD linked oxidase domain protein
Q425_RS12275	COG0277	FAD linked oxidase domain protein
Q425_RS12280	COG0277	FAD linked oxidase domain protein
Q425_RS12285	COG0247	lactate metabolic process
Q425_RS12290	COG2819	hydrolase of the alpha beta superfamily
Q425_RS12325	COG0583	DNA-binding transcription factor activity
Q425_RS12330	COG0482	sulfurtransferase activity
Q425_RS12335	COG0730	response to heat
Q425_RS12340	COG0625	glutathione transferase activity
Q425_RS12345	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Q425_RS12350	COG3909	cytochrome
Q425_RS12390	COG0154	amidase activity
Q425_RS12395	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Q425_RS12400	COG1024	Enoyl-CoA hydratase
Q425_RS12415	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Q425_RS12430	COG1028	Short-chain dehydrogenase reductase Sdr
Q425_RS12435	COG1414	Transcriptional regulator
Q425_RS12445	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Q425_RS12450	COG0251	oxidation-reduction process
Q425_RS12455	COG0559	Belongs to the binding-protein-dependent transport system permease family
Q425_RS12475	COG1902	pentaerythritol trinitrate reductase activity
Q425_RS12485	COG0583	DNA-binding transcription factor activity
Q425_RS12495	COG0590	tRNA wobble adenosine to inosine editing
Q425_RS12500	COG2807	transmembrane transport
Q425_RS12510	COG3181	Tripartite tricarboxylate transporter family receptor
Q425_RS12520	COG0154	amidase activity
Q425_RS12525	COG0307	riboflavin synthase, alpha
Q425_RS12530	COG3181	Tripartite tricarboxylate transporter family receptor
Q425_RS12535	COG1522	sequence-specific DNA binding
Q425_RS12545	COG0318	PFAM AMP-dependent synthetase and ligase
Q425_RS12555	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Q425_RS12575	COG1063	alcohol dehydrogenase
Q425_RS12600	COG1418	mRNA catabolic process
Q425_RS12605	COG1448	Aminotransferase
Q425_RS12610	COG0583	DNA-binding transcription factor activity
Q425_RS12620	COG0477	Major facilitator Superfamily
Q425_RS12625	COG1028	Short-chain dehydrogenase reductase Sdr
Q425_RS12640	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
Q425_RS12645	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Q425_RS12650	COG0583	DNA-binding transcription factor activity
Q425_RS12690	COG1028	Short-chain dehydrogenase reductase Sdr
Q425_RS12695	COG1309	transcriptional regulator
Q425_RS12700	COG2982	Protein involved in outer membrane biogenesis
Q425_RS12705	COG2818	Glycosylase
Q425_RS12725	COG1653	transport
Q425_RS12735	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Q425_RS12740	COG3842	ATPase activity
Q425_RS12745	COG0395	ABC-type sugar transport system, permease component
Q425_RS12750	COG1175	transmembrane transport
Q425_RS12770	COG3181	Tripartite tricarboxylate transporter family receptor
Q425_RS12775	COG2186	Transcriptional regulator
Q425_RS12810	COG2011	ABC-type metal ion transport system permease component
Q425_RS12815	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
Q425_RS12820	COG1501	Belongs to the glycosyl hydrolase 31 family
Q425_RS12840	COG0318	PFAM AMP-dependent synthetase and ligase
Q425_RS12845	COG1473	amidohydrolase
Q425_RS12855	COG2855	membrane
Q425_RS12865	COG2239	Acts as a magnesium transporter
Q425_RS12885	COG3181	Tripartite tricarboxylate transporter family receptor
Q425_RS12895	COG1722	exodeoxyribonuclease VII activity
Q425_RS12900	COG0142	geranyltranstransferase activity
Q425_RS12905	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Q425_RS12910	COG1469	GTP cyclohydrolase I activity
Q425_RS12915	COG0360	Binds together with S18 to 16S ribosomal RNA
Q425_RS12920	COG2965	DNA replication, synthesis of RNA primer
Q425_RS12925	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Q425_RS12930	COG0359	binds to the 23S rRNA
Q425_RS12940	COG0305	Participates in initiation and elongation during chromosome replication
Q425_RS12950	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Q425_RS12955	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
Q425_RS12960	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Q425_RS12965	COG3737	Protein of unknown function (DUF498/DUF598)
Q425_RS12970	COG0436	Aminotransferase
Q425_RS12995	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
Q425_RS13025	COG0268	Binds directly to 16S ribosomal RNA
Q425_RS13035	COG0728	peptidoglycan biosynthetic process
Q425_RS13045	COG0563	adenylate kinase activity
Q425_RS13050	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
Q425_RS13055	COG2835	tetraacyldisaccharide 4'-kinase activity
Q425_RS13060	COG1663	tetraacyldisaccharide 4'-kinase activity
Q425_RS13065	COG0848	biopolymer transport protein
Q425_RS13070	COG0811	peptide transport
Q425_RS13080	COG1570	exodeoxyribonuclease VII activity
Q425_RS13085	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
Q425_RS13090	COG0038	chloride channel
Q425_RS13095	COG0183	Belongs to the thiolase family
Q425_RS13105	COG1278	Cold shock
Q425_RS13110	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
Q425_RS13120	COG4953	penicillin-binding protein 1C
Q425_RS13125	COG0542	response to heat
Q425_RS13130	COG2995	paraquat-inducible protein a
Q425_RS13135	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
Q425_RS13135	COG3008	intermembrane lipid transfer
Q425_RS13145	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
Q425_RS13145	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
Q425_RS13145	COG0506	proline dehydrogenase activity
Q425_RS13180	COG2271	Major facilitator Superfamily
Q425_RS13185	COG1309	transcriptional regulator
Q425_RS13195	COG3468	outer membrane autotransporter barrel domain protein
Q425_RS13225	COG0477	Major facilitator Superfamily
Q425_RS13235	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Q425_RS13240	COG1845	cytochrome c oxidase, subunit III
Q425_RS13245	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
Q425_RS13255	COG1028	Short-chain dehydrogenase reductase Sdr
Q425_RS13275	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Q425_RS13280	COG0303	'Molybdopterin
Q425_RS13285	COG0521	Mo-molybdopterin cofactor biosynthetic process
Q425_RS13300	COG0315	cyclic pyranopterin monophosphate synthase activity
Q425_RS13310	COG0412	Dienelactone hydrolase
Q425_RS13320	COG0678	peroxiredoxin activity
Q425_RS13330	COG0697	spore germination
Q425_RS13335	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Q425_RS13360	COG0789	Transcriptional regulator
Q425_RS13370	COG3468	outer membrane autotransporter barrel domain protein
Q425_RS13375	COG3468	outer membrane autotransporter barrel domain protein
Q425_RS13385	COG5441	Belongs to the UPF0261 family
Q425_RS13390	COG5564	TIM-barrel signal transduction protein
Q425_RS13405	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
Q425_RS13420	COG1477	protein flavinylation
Q425_RS13440	COG1131	(ABC) transporter
Q425_RS13445	COG0842	Transport permease protein
Q425_RS13455	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Q425_RS13460	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
Q425_RS13460	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
Q425_RS13465	COG1562	ergosterol biosynthetic process
Q425_RS13470	COG1562	ergosterol biosynthetic process
Q425_RS13475	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Q425_RS13480	COG1028	Short-chain dehydrogenase reductase Sdr
Q425_RS13500	COG2304	oxidoreductase activity
Q425_RS13520	COG0534	Mate efflux family protein
Q425_RS13530	COG0254	rRNA binding
Q425_RS13535	COG3483	tryptophan 2,3-dioxygenase activity
Q425_RS13540	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
Q425_RS13545	COG2003	Belongs to the UPF0758 family
Q425_RS13550	COG1047	Peptidyl-prolyl cis-trans
Q425_RS13555	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Q425_RS13560	COG0625	glutathione transferase activity
Q425_RS13580	COG0523	cobalamin synthesis protein
Q425_RS13590	COG0583	DNA-binding transcription factor activity
Q425_RS13600	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
Q425_RS13605	COG1187	pseudouridine synthase activity
Q425_RS13610	COG0779	Required for maturation of 30S ribosomal subunits
Q425_RS13615	COG0195	Participates in both transcription termination and antitermination
Q425_RS13615	COG2251	uridine kinase activity
Q425_RS13620	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Q425_RS13625	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Q425_RS13630	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Q425_RS13650	COG1611	Belongs to the LOG family
Q425_RS13665	COG0412	Dienelactone hydrolase
Q425_RS13670	COG1283	sodium-dependent phosphate transmembrane transporter activity
Q425_RS13675	COG1760	l-serine dehydratase
Q425_RS13680	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
Q425_RS13685	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
Q425_RS13695	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
Q425_RS13720	COG2311	Membrane
Q425_RS13740	COG3842	ATPase activity
Q425_RS13745	COG0395	ABC-type sugar transport system, permease component
Q425_RS13750	COG1175	transmembrane transport
Q425_RS13755	COG1653	transport
Q425_RS13765	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
Q425_RS13780	COG0559	Belongs to the binding-protein-dependent transport system permease family
Q425_RS13800	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
Q425_RS13815	COG0697	spore germination
Q425_RS13830	COG2363	Small membrane protein
Q425_RS13845	COG1464	Belongs to the NlpA lipoprotein family
Q425_RS13855	COG0688	phosphatidylethanolamine metabolic process
Q425_RS13870	COG0095	Lipoate-protein ligase
Q425_RS13885	COG0625	glutathione transferase activity
Q425_RS13890	COG0386	Belongs to the glutathione peroxidase family
Q425_RS13910	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Q425_RS13940	COG2259	Doxx family
Q425_RS13955	COG0667	Aldo Keto reductase
Q425_RS13985	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
Q425_RS14000	COG1640	4-alpha-glucanotransferase
Q425_RS14010	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Q425_RS14020	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Q425_RS14060	COG0392	lysyltransferase activity
Q425_RS14080	COG3395	kinase activity
Q425_RS14085	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Q425_RS14100	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
Q425_RS14110	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Q425_RS14140	COG0747	negative chemotaxis
Q425_RS14145	COG0601	transmembrane transport
Q425_RS14150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Q425_RS14155	COG4172	Belongs to the ABC transporter superfamily
Q425_RS14160	COG0154	amidase activity
Q425_RS14210	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Q425_RS14215	COG0425	Belongs to the sulfur carrier protein TusA family
Q425_RS14225	COG0228	four-way junction DNA binding
Q425_RS14230	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
Q425_RS14235	COG0336	Belongs to the RNA methyltransferase TrmD family
Q425_RS14240	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Q425_RS14255	COG0642	Histidine kinase
Q425_RS14270	COG0525	valine-tRNA ligase activity
Q425_RS14275	COG0105	UTP biosynthetic process
Q425_RS14280	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Q425_RS14290	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
Q425_RS14295	COG0124	histidyl-tRNA synthetase
Q425_RS14300	COG2976	Protein conserved in bacteria
Q425_RS14305	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Q425_RS14310	COG1160	GTP binding
Q425_RS14315	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Q425_RS14320	COG1923	regulation of RNA biosynthetic process
Q425_RS14325	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Q425_RS14330	COG0330	HflC and HflK could
Q425_RS14335	COG0330	HflC and HflK could
Q425_RS14340	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
Q425_RS14345	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Q425_RS14350	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
Q425_RS14355	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Q425_RS14365	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Q425_RS14390	COG0628	permease
Q425_RS14395	COG0842	Transport permease protein
Q425_RS14400	COG1131	(ABC) transporter
Q425_RS14470	COG0156	8-amino-7-oxononanoate synthase activity
Q425_RS14480	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
Q425_RS14480	COG4106	trans-aconitate 2-methyltransferase activity
Q425_RS14485	COG1380	Effector of murein hydrolase LrgA
Q425_RS14490	COG1346	cytolysis
Q425_RS14500	COG3284	Transcriptional regulator
Q425_RS14505	COG1012	belongs to the aldehyde dehydrogenase family
Q425_RS14520	COG2733	membrane
Q425_RS14525	COG0583	DNA-binding transcription factor activity
Q425_RS14530	COG0384	phenazine biosynthesis protein PhzF
Q425_RS14535	COG5507	3-demethylubiquinone-9 3-methyltransferase
Q425_RS14540	COG2169	Transcriptional regulator
Q425_RS14570	COG0659	secondary active sulfate transmembrane transporter activity
Q425_RS14625	COG2207	Transcriptional regulator
Q425_RS14755	COG2346	COG2346, Truncated hemoglobins
Q425_RS14780	COG0583	DNA-binding transcription factor activity
Q425_RS14785	COG4692	amylo-alpha-1,6-glucosidase activity
Q425_RS14795	COG0183	Belongs to the thiolase family
Q425_RS14810	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Q425_RS14815	COG0633	Ferredoxin
Q425_RS14825	COG1024	Enoyl-CoA hydratase
Q425_RS14835	COG4638	Rieske (2fe-2S)
Q425_RS14845	COG0559	Belongs to the binding-protein-dependent transport system permease family
Q425_RS14865	COG2224	Isocitrate lyase
Q425_RS14870	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Q425_RS14870	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Q425_RS14885	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Q425_RS14890	COG0322	excinuclease ABC activity
Q425_RS14895	COG1472	Belongs to the glycosyl hydrolase 3 family
Q425_RS14900	COG0736	holo-[acyl-carrier-protein] synthase activity
Q425_RS14905	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
Q425_RS14915	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Q425_RS14920	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Q425_RS14945	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
Q425_RS14960	COG2032	superoxide dismutase activity
Q425_RS14975	COG1024	Enoyl-CoA hydratase
Q425_RS14985	COG1802	Transcriptional regulator
Q425_RS14995	COG0183	Belongs to the thiolase family
Q425_RS15000	COG1942	4-Oxalocrotonate Tautomerase
Q425_RS15010	COG4176	ABC-type proline glycine betaine transport system permease component
Q425_RS15025	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Q425_RS15030	COG2814	Major facilitator Superfamily
Q425_RS15035	COG0227	Belongs to the bacterial ribosomal protein bL28 family
Q425_RS15040	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Q425_RS15065	COG2814	Major facilitator Superfamily
Q425_RS15070	COG0495	leucyl-tRNA aminoacylation
Q425_RS15085	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Q425_RS15095	COG0154	amidase activity
Q425_RS15100	COG1250	3-hydroxyacyl-CoA dehydrogenase
Q425_RS15150	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Q425_RS15155	COG4654	Cytochrome c, class I
Q425_RS15160	COG0129	dihydroxy-acid dehydratase activity
Q425_RS15165	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Q425_RS15210	COG2084	Dehydrogenase
Q425_RS15215	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
Q425_RS15225	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
Q425_RS15230	COG0513	Belongs to the DEAD box helicase family
Q425_RS15240	COG0617	tRNA 3'-terminal CCA addition
Q425_RS15255	COG0477	Major facilitator Superfamily
Q425_RS15265	COG0583	DNA-binding transcription factor activity
Q425_RS15285	COG1950	PFAM Membrane protein of
Q425_RS15290	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
Q425_RS15305	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Q425_RS15315	COG1560	Kdo2-lipid A biosynthetic process
Q425_RS15320	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Q425_RS15330	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
Q425_RS15340	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
Q425_RS15350	COG0803	Belongs to the bacterial solute-binding protein 9 family
Q425_RS15370	COG0735	belongs to the Fur family
Q425_RS15375	COG0523	cobalamin synthesis protein
Q425_RS15385	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
Q425_RS15390	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
Q425_RS15400	COG2096	Adenosyltransferase
Q425_RS15460	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
Q425_RS15465	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Q425_RS15480	COG0745	RESPONSE REGULATOR receiver
Q425_RS15525	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Q425_RS15545	COG0582	viral genome integration into host DNA
Q425_RS15550	COG0012	GTP binding
Q425_RS15560	COG0193	aminoacyl-tRNA hydrolase activity
Q425_RS15565	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
Q425_RS15570	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Q425_RS15580	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Q425_RS15585	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
Q425_RS15595	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Q425_RS15620	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
Q425_RS15630	COG1368	sulfuric ester hydrolase activity
Q425_RS15635	COG0642	Histidine kinase
Q425_RS15640	COG0745	RESPONSE REGULATOR receiver
Q425_RS15645	COG0277	FAD linked oxidase domain protein
Q425_RS15660	COG0166	Belongs to the GPI family
Q425_RS15665	COG0438	transferase activity, transferring glycosyl groups
Q425_RS15670	COG0438	transferase activity, transferring glycosyl groups
Q425_RS15685	COG0438	transferase activity, transferring glycosyl groups
Q425_RS15700	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
Q425_RS15705	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Q425_RS15710	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
Q425_RS15720	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
Q425_RS15730	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Q425_RS15735	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Q425_RS15745	COG0747	negative chemotaxis
Q425_RS15750	COG0601	transmembrane transport
Q425_RS15760	COG0601	transmembrane transport
Q425_RS15765	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Q425_RS15785	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
Q425_RS15790	COG0830	nickel cation binding
Q425_RS15800	COG0804	urea catabolic process
Q425_RS15805	COG0832	Belongs to the urease beta subunit family
Q425_RS15815	COG0831	urea catabolic process
Q425_RS15820	COG0829	nickel cation binding
Q425_RS15830	COG0633	Ferredoxin
Q425_RS15845	COG2188	Transcriptional regulator
Q425_RS15870	COG2719	SpoVR family
Q425_RS15875	COG2718	Belongs to the UPF0229 family
Q425_RS15890	COG1028	Short-chain dehydrogenase reductase Sdr
Q425_RS15895	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Q425_RS15910	COG1960	acyl-CoA dehydrogenase activity
Q425_RS15955	COG0183	Belongs to the thiolase family
Q425_RS15960	COG2030	dehydratase
Q425_RS16005	COG0328	RNA-DNA hybrid ribonuclease activity
Q425_RS16010	COG2226	methyltransferase
Q425_RS16015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Q425_RS16020	COG1388	LysM domain
Q425_RS16020	COG0741	lytic transglycosylase activity
Q425_RS16040	COG2979	Protein of unknown function (DUF533)
Q425_RS16075	COG1271	oxidase subunit
Q425_RS16080	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Q425_RS16085	COG0850	regulation of cytokinetic process
Q425_RS16090	COG2894	cell division
Q425_RS16095	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
Q425_RS16115	COG0488	(ABC) transporter
Q425_RS16125	COG0601	transmembrane transport
Q425_RS16135	COG1215	transferase activity, transferring glycosyl groups
Q425_RS16150	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Q425_RS16160	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Q425_RS16180	COG0318	PFAM AMP-dependent synthetase and ligase
Q425_RS16185	COG2188	Transcriptional regulator
Q425_RS16190	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
Q425_RS16195	COG2814	Major facilitator Superfamily
Q425_RS16205	COG0259	pyridoxamine-phosphate oxidase activity
Q425_RS16210	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Q425_RS16225	COG0583	DNA-binding transcription factor activity
Q425_RS16230	COG1960	acyl-CoA dehydrogenase activity
Q425_RS16255	COG0134	indole-3-glycerol-phosphate synthase activity
Q425_RS16260	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Q425_RS16265	COG0512	Glutamine amidotransferase of anthranilate synthase
Q425_RS16275	COG0546	phosphoglycolate phosphatase activity
Q425_RS16280	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Q425_RS16285	COG2967	ApaG domain
Q425_RS16290	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
Q425_RS16295	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Q425_RS16300	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Q425_RS16305	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Q425_RS16315	COG0037	tRNA processing
Q425_RS16325	COG3634	alkyl hydroperoxide reductase activity
Q425_RS16330	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Q425_RS16335	COG1024	Enoyl-CoA hydratase
Q425_RS16360	COG0356	it plays a direct role in the translocation of protons across the membrane
Q425_RS16370	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Q425_RS16375	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Q425_RS16380	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Q425_RS16385	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Q425_RS16390	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Q425_RS16395	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Q425_RS16405	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
Q425_RS16410	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Q425_RS16415	COG0210	DNA helicase
Q425_RS16425	COG2195	Cleaves the N-terminal amino acid of tripeptides
Q425_RS16445	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Q425_RS16450	COG0601	transmembrane transport
Q425_RS16470	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Q425_RS16475	COG1024	Enoyl-CoA hydratase
Q425_RS16480	COG1024	Enoyl-CoA hydratase
Q425_RS16505	COG1250	3-hydroxyacyl-CoA dehydrogenase
Q425_RS16545	COG0700	Nucleoside recognition
Q425_RS16550	COG0469	pyruvate kinase activity
Q425_RS16555	COG1929	Belongs to the glycerate kinase type-1 family
Q425_RS16560	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Q425_RS16565	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Q425_RS16570	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
Q425_RS16580	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Q425_RS16590	COG2154	pterin-4-alpha-carbinolamine dehydratase
Q425_RS16615	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Q425_RS16620	COG0154	amidase activity
Q425_RS16630	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Q425_RS16635	COG0601	transmembrane transport
Q425_RS16660	COG0019	diaminopimelate decarboxylase activity
Q425_RS16680	COG2353	YceI-like domain
Q425_RS16685	COG4774	siderophore transport
Q425_RS16690	COG3712	iron ion homeostasis
Q425_RS16730	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
Q425_RS16735	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Q425_RS16740	COG0211	Belongs to the bacterial ribosomal protein bL27 family
Q425_RS16745	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Q425_RS16755	COG0142	geranyltranstransferase activity
Q425_RS16765	COG0583	DNA-binding transcription factor activity
Q425_RS16775	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
Q425_RS16780	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Q425_RS16795	COG2994	toxin metabolic process
Q425_RS16805	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
Q425_RS16810	COG2274	protein secretion by the type I secretion system
Q425_RS16815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Q425_RS16820	COG1538	Outer membrane efflux protein
Q425_RS16840	COG0765	amino acid transport
Q425_RS16845	COG1126	abc transporter atp-binding protein
Q425_RS16865	COG1028	Short-chain dehydrogenase reductase Sdr
Q425_RS16875	COG1802	Transcriptional regulator
Q425_RS16885	COG1802	Transcriptional regulator
Q425_RS16895	COG0318	PFAM AMP-dependent synthetase and ligase
Q425_RS16905	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Q425_RS16925	COG0028	Belongs to the TPP enzyme family
Q425_RS16940	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Q425_RS16945	COG0583	DNA-binding transcription factor activity
Q425_RS16955	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Q425_RS16980	COG0251	oxidation-reduction process
Q425_RS16985	COG1017	nitric oxide dioxygenase activity
Q425_RS16985	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Q425_RS16990	COG2031	fatty acid transporter
Q425_RS16995	COG1012	belongs to the aldehyde dehydrogenase family
Q425_RS17000	COG1802	Transcriptional regulator
Q425_RS17010	COG1278	Cold shock
Q425_RS17015	COG0583	DNA-binding transcription factor activity
Q425_RS17045	COG1960	acyl-CoA dehydrogenase activity
Q425_RS17050	COG0583	DNA-binding transcription factor activity
Q425_RS17055	COG3181	Tripartite tricarboxylate transporter family receptor
Q425_RS17060	COG1024	Enoyl-CoA hydratase
Q425_RS17065	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Q425_RS17070	COG1253	flavin adenine dinucleotide binding
Q425_RS17075	COG1285	pathogenesis
Q425_RS17085	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Q425_RS17100	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Q425_RS17110	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Q425_RS17115	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
Q425_RS17130	COG2031	fatty acid transporter
Q425_RS17140	COG0786	glutamate:sodium symporter activity
Q425_RS17155	COG0463	Glycosyl transferase, family 2
Q425_RS17160	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
Q425_RS17185	COG0697	spore germination
Q425_RS17200	COG3181	Tripartite tricarboxylate transporter family receptor
Q425_RS17225	COG0028	Belongs to the TPP enzyme family
Q425_RS17230	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Q425_RS17235	COG1024	Enoyl-CoA hydratase
Q425_RS17235	COG1250	3-hydroxyacyl-CoA dehydrogenase
Q425_RS17240	COG3181	Tripartite tricarboxylate transporter family receptor
Q425_RS17250	COG0492	ferredoxin-NADP+ reductase activity
Q425_RS17275	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Q425_RS17285	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Q425_RS17305	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Q425_RS17320	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
Q425_RS17325	COG2823	Periplasmic or secreted lipoprotein
Q425_RS17340	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Q425_RS17350	COG1309	transcriptional regulator
Q425_RS17355	COG0471	metal ion transport
Q425_RS17360	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
Q425_RS17365	COG0772	Belongs to the SEDS family
Q425_RS17370	COG0768	penicillin binding
Q425_RS17380	COG1792	Involved in formation and maintenance of cell shape
Q425_RS17385	COG1077	Cell shape determining protein MreB Mrl
Q425_RS17390	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Q425_RS17395	COG0154	amidase activity
Q425_RS17400	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Q425_RS17405	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Q425_RS17410	COG0708	Exodeoxyribonuclease III
Q425_RS17415	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Q425_RS17420	COG2860	membrane
Q425_RS17455	COG1012	belongs to the aldehyde dehydrogenase family
Q425_RS17465	COG3069	C4-dicarboxylate transmembrane transporter activity
Q425_RS17475	COG1802	Transcriptional regulator
Q425_RS17485	COG2423	ornithine cyclodeaminase activity
Q425_RS17510	COG1595	DNA-templated transcription, initiation
Q425_RS17515	COG3712	iron ion homeostasis
Q425_RS17525	COG3720	iron ion transport
Q425_RS17530	COG4558	Periplasmic binding protein
Q425_RS17535	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Q425_RS17540	COG1120	ATPase activity
Q425_RS17545	COG1683	Conserved Protein
Q425_RS17575	COG3064	Membrane
Q425_RS17590	COG1234	tRNA 3'-trailer cleavage
Q425_RS17625	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Q425_RS17635	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Q425_RS17650	COG0540	Belongs to the ATCase OTCase family
Q425_RS17655	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
Q425_RS17660	COG1678	Uncharacterized ACR, COG1678
Q425_RS17675	COG0352	thiamine-phosphate diphosphorylase activity
Q425_RS17680	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Q425_RS17705	COG1960	acyl-CoA dehydrogenase activity
Q425_RS17710	COG1024	Enoyl-CoA hydratase
Q425_RS17790	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Q425_RS17795	COG0793	Belongs to the peptidase S41A family
Q425_RS17800	COG4942	peptidase
Q425_RS17805	COG0588	phosphoglycerate mutase activity
Q425_RS17810	COG1054	Belongs to the UPF0176 family
Q425_RS17815	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
Q425_RS17820	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
Q425_RS17825	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Q425_RS17830	COG3181	Tripartite tricarboxylate transporter family receptor
Q425_RS17845	COG2226	methyltransferase
Q425_RS17850	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
Q425_RS17865	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Q425_RS17890	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
Q425_RS17915	COG1335	isochorismatase
Q425_RS17920	COG2309	aminopeptidase activity
Q425_RS17925	COG0596	Alpha beta hydrolase
Q425_RS17930	COG3473	Maleate cis-trans isomerase
Q425_RS17940	COG2068	MobA-Related Protein
Q425_RS17965	COG2204	response regulator
Q425_RS17970	COG5000	phosphorelay sensor kinase activity
Q425_RS17980	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Q425_RS17980	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Q425_RS17990	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
Q425_RS18010	COG0583	DNA-binding transcription factor activity
Q425_RS18025	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
Q425_RS18030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Q425_RS18035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Q425_RS18050	COG0758	DNA mediated transformation
Q425_RS18055	COG1522	sequence-specific DNA binding
Q425_RS18065	COG0242	peptide deformylase activity
Q425_RS18070	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Q425_RS18080	COG0546	phosphoglycolate phosphatase activity
Q425_RS18100	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Q425_RS18105	COG1942	4-Oxalocrotonate Tautomerase
Q425_RS18110	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Q425_RS18135	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Q425_RS18155	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Q425_RS18160	COG1024	Enoyl-CoA hydratase
Q425_RS18165	COG1414	Transcriptional regulator
Q425_RS18170	COG0318	PFAM AMP-dependent synthetase and ligase
Q425_RS18175	COG3181	Tripartite tricarboxylate transporter family receptor
Q425_RS18205	COG0583	DNA-binding transcription factor activity
Q425_RS18220	COG3422	double-strand break repair
Q425_RS18225	COG0330	HflC and HflK could
Q425_RS18235	COG0251	oxidation-reduction process
Q425_RS18245	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
Q425_RS18255	COG0583	DNA-binding transcription factor activity
Q425_RS18260	COG2814	Major facilitator Superfamily
Q425_RS18265	COG0129	dihydroxy-acid dehydratase activity
Q425_RS18270	COG2207	Transcriptional regulator
Q425_RS18275	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Q425_RS18285	COG0657	acetylesterase activity
Q425_RS18290	COG0747	negative chemotaxis
Q425_RS18295	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Q425_RS18300	COG2808	Putative FMN-binding domain
Q425_RS18315	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
Q425_RS18320	COG1970	mechanosensitive ion channel activity
Q425_RS18325	COG0723	plastoquinol--plastocyanin reductase activity
Q425_RS18330	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Q425_RS18335	COG2857	Cytochrome c1
Q425_RS18340	COG0625	glutathione transferase activity
Q425_RS18345	COG2969	positive regulation of protein catabolic process
Q425_RS18370	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
Q425_RS18385	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Q425_RS18390	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
Q425_RS18395	COG4988	ABC transporter
Q425_RS18405	COG1294	oxidase, subunit
Q425_RS18430	COG1960	acyl-CoA dehydrogenase activity
Q425_RS18440	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Q425_RS18445	COG0405	Gamma-glutamyltransferase
Q425_RS18455	COG3181	Tripartite tricarboxylate transporter family receptor
Q425_RS18465	COG0114	fumarate hydratase activity
Q425_RS18470	COG0802	atpase or kinase
Q425_RS18475	COG0860	N-Acetylmuramoyl-L-alanine amidase
Q425_RS18480	COG0586	Pfam SNARE associated Golgi protein
Q425_RS18485	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
Q425_RS18490	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Q425_RS18495	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Q425_RS18510	COG0617	tRNA 3'-terminal CCA addition
Q425_RS18535	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
Q425_RS18540	COG2188	Transcriptional regulator
Q425_RS18550	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Q425_RS18560	COG1028	Short-chain dehydrogenase reductase Sdr
Q425_RS18585	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Q425_RS18590	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
Q425_RS18595	COG1012	belongs to the aldehyde dehydrogenase family
Q425_RS18620	COG3181	Tripartite tricarboxylate transporter family receptor
Q425_RS18625	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Q425_RS18630	COG1024	Enoyl-CoA hydratase
Q425_RS18650	COG1024	Enoyl-CoA hydratase
Q425_RS18665	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Q425_RS18670	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Q425_RS18680	COG2226	methyltransferase
Q425_RS18690	COG1194	a g-specific adenine glycosylase
Q425_RS18700	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
Q425_RS18705	COG2177	Part of the ABC transporter FtsEX involved in
Q425_RS18710	COG2884	Cell division ATP-binding protein ftsE
Q425_RS18715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Q425_RS18720	COG4597	amino acid ABC transporter
Q425_RS18725	COG0765	amino acid transport
Q425_RS18730	COG1126	abc transporter atp-binding protein
Q425_RS18745	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Q425_RS18750	COG0477	Major facilitator Superfamily
Q425_RS18760	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
Q425_RS18765	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Q425_RS18780	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
Q425_RS18785	COG0237	dephospho-CoA kinase activity
Q425_RS18790	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
Q425_RS18840	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Q425_RS18855	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Q425_RS18870	COG1652	LysM domain
Q425_RS18880	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Q425_RS18885	COG1956	GAF domain-containing protein
Q425_RS18890	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Q425_RS18910	COG2186	Transcriptional regulator
Q425_RS18915	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
Q425_RS18940	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Q425_RS18960	COG0438	transferase activity, transferring glycosyl groups
Q425_RS18970	COG0402	S-adenosylhomocysteine deaminase activity
Q425_RS19015	COG0629	single-stranded DNA binding
Q425_RS19020	COG2814	Major facilitator Superfamily
Q425_RS19035	COG0232	Belongs to the dGTPase family. Type 2 subfamily
Q425_RS19040	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Q425_RS19045	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Q425_RS19055	COG1965	Belongs to the frataxin family
Q425_RS19065	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Q425_RS19070	COG1333	cytochrome c biogenesis protein
Q425_RS19080	COG0218	Necessary for normal cell division and for the maintenance of normal septation
Q425_RS19095	COG4232	protein-disulfide reductase activity
Q425_RS19100	COG1324	tolerance protein
Q425_RS19105	COG0537	adenosine 5'-monophosphoramidase activity
Q425_RS19110	COG0203	ribosomal protein L17
Q425_RS19115	COG0202	RNA polymerase activity
Q425_RS19120	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Q425_RS19125	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Q425_RS19130	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Q425_RS19135	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Q425_RS19140	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Q425_RS19145	COG0201	protein transport
Q425_RS19150	COG0200	Binds to the 23S rRNA
Q425_RS19155	COG1841	ribosomal large subunit assembly
Q425_RS19160	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
Q425_RS19165	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Q425_RS19170	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Q425_RS19175	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Q425_RS19180	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Q425_RS19185	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Q425_RS19190	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Q425_RS19195	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Q425_RS19215	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Q425_RS19220	COG0255	Belongs to the universal ribosomal protein uL29 family
Q425_RS19225	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Q425_RS19230	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Q425_RS19235	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Q425_RS19240	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Q425_RS19245	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Q425_RS19250	COG0089	rRNA binding
Q425_RS19255	COG0088	Forms part of the polypeptide exit tunnel
Q425_RS19260	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Q425_RS19265	COG0051	transcription antitermination factor activity, RNA binding
Q425_RS19270	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Q425_RS19275	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Q425_RS19280	COG0049	tRNA binding
Q425_RS19285	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Q425_RS19295	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Q425_RS19305	COG0628	permease
Q425_RS19315	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
Q425_RS19330	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
Q425_RS19335	COG0351	phosphomethylpyrimidine kinase
Q425_RS19340	COG2022	thiamine diphosphate biosynthetic process
Q425_RS19345	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Q425_RS19350	COG4206	TonB-dependent receptor
Q425_RS19370	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Q425_RS19380	COG3781	membrane
Q425_RS19385	COG1522	sequence-specific DNA binding
Q425_RS19390	COG0028	Belongs to the TPP enzyme family
Q425_RS19400	COG1012	belongs to the aldehyde dehydrogenase family
Q425_RS19405	COG1028	Short-chain dehydrogenase reductase Sdr
Q425_RS19410	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Q425_RS19415	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
Q425_RS19440	COG2922	Belongs to the Smg family
Q425_RS19445	COG1629	transport
Q425_RS19455	COG2358	TRAP transporter, solute receptor (TAXI family
Q425_RS19465	COG3181	Tripartite tricarboxylate transporter family receptor
Q425_RS19470	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Q425_RS19485	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Q425_RS19490	COG0183	Belongs to the thiolase family
Q425_RS19500	COG1960	acyl-CoA dehydrogenase activity
Q425_RS19520	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Q425_RS19535	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
Q425_RS19545	COG1414	Transcriptional regulator
Q425_RS19550	COG1028	Short-chain dehydrogenase reductase Sdr
Q425_RS19555	COG2031	fatty acid transporter
Q425_RS19560	COG1250	3-hydroxyacyl-CoA dehydrogenase
Q425_RS19570	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
Q425_RS19575	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
Q425_RS19585	COG4257	antibiotic catabolic process
Q425_RS19595	COG0753	catalase activity
Q425_RS19600	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Q425_RS19605	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
Q425_RS19615	COG2175	clavaminate synthase activity
Q425_RS19620	COG1473	amidohydrolase
Q425_RS19625	COG4608	Belongs to the ABC transporter superfamily
Q425_RS19630	COG0444	Belongs to the ABC transporter superfamily
Q425_RS19645	COG0747	negative chemotaxis
Q425_RS19650	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Q425_RS19685	COG0436	Aminotransferase
Q425_RS19690	COG1278	Cold shock
Q425_RS19705	COG1596	polysaccharide export
Q425_RS19705	COG1555	photosystem II stabilization
Q425_RS19735	COG4172	Belongs to the ABC transporter superfamily