locus-tag	class	description
BH373_RS00005	COG0445	tRNA wobble uridine modification
BH373_RS00010	COG0357	Ribosomal RNA small subunit methyltransferase G
BH373_RS00015	COG1192	Involved in chromosome partitioning
BH373_RS00025	COG1475	DNA binding
BH373_RS00030	COG0252	asparaginase activity
BH373_RS00055	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BH373_RS00065	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BH373_RS00075	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BH373_RS00080	COG0081	regulation of translation
BH373_RS00085	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BH373_RS00090	COG0222	ribosome binding
BH373_RS00095	COG0085	RNA polymerase activity
BH373_RS00100	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BH373_RS00140	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH373_RS00165	COG1024	Enoyl-CoA hydratase
BH373_RS00190	COG0752	glycyl-tRNA synthetase alpha subunit
BH373_RS00195	COG0751	glycine-tRNA ligase activity
BH373_RS00200	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BH373_RS00205	COG0204	Acyl-transferase
BH373_RS00220	COG0242	peptide deformylase activity
BH373_RS00260	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BH373_RS00265	COG2813	Specifically methylates the guanine in position
BH373_RS00265	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BH373_RS00275	COG2223	nitrite transmembrane transporter activity
BH373_RS00285	COG1794	racemase activity, acting on amino acids and derivatives
BH373_RS00290	COG1126	abc transporter atp-binding protein
BH373_RS00295	COG0765	amino acid transport
BH373_RS00300	COG0765	amino acid transport
BH373_RS00305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BH373_RS00365	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BH373_RS00395	COG0326	Molecular chaperone. Has ATPase activity
BH373_RS00400	COG0625	glutathione transferase activity
BH373_RS00415	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BH373_RS00420	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BH373_RS00450	COG0438	transferase activity, transferring glycosyl groups
BH373_RS00455	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BH373_RS00460	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BH373_RS00490	COG0859	PFAM glycosyl transferase family 9
BH373_RS00505	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BH373_RS00515	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BH373_RS00520	COG1127	ABC transporter
BH373_RS00545	COG1686	Belongs to the peptidase S11 family
BH373_RS00555	COG2921	Belongs to the UPF0250 family
BH373_RS00560	COG0321	lipoyl(octanoyl) transferase activity
BH373_RS00565	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BH373_RS00600	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BH373_RS00610	COG0018	arginyl-trna synthetase
BH373_RS00630	COG0395	ABC-type sugar transport system, permease component
BH373_RS00635	COG1175	transmembrane transport
BH373_RS00640	COG1653	transport
BH373_RS00645	COG3842	ATPase activity
BH373_RS00650	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BH373_RS00660	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BH373_RS00680	COG1609	Transcriptional regulator
BH373_RS00690	COG0154	amidase activity
BH373_RS00695	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BH373_RS00705	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BH373_RS00715	COG0583	DNA-binding transcription factor activity
BH373_RS00735	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BH373_RS00750	COG1802	Transcriptional regulator
BH373_RS00765	COG1024	Enoyl-CoA hydratase
BH373_RS00780	COG3181	Tripartite tricarboxylate transporter family receptor
BH373_RS00795	COG1984	allophanate hydrolase subunit 2
BH373_RS00800	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BH373_RS00810	COG0583	DNA-binding transcription factor activity
BH373_RS00815	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BH373_RS00825	COG5002	protein histidine kinase activity
BH373_RS00835	COG5002	protein histidine kinase activity
BH373_RS00840	COG0745	RESPONSE REGULATOR receiver
BH373_RS00845	COG2226	methyltransferase
BH373_RS00860	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BH373_RS00880	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BH373_RS00890	COG0513	Belongs to the DEAD box helicase family
BH373_RS00895	COG1280	lysine exporter protein (LysE YggA)
BH373_RS00900	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BH373_RS00945	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BH373_RS00945	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BH373_RS00955	COG0489	protein tyrosine kinase activity
BH373_RS00970	COG0717	Belongs to the dCTP deaminase family
BH373_RS00995	COG1982	Orn Lys Arg decarboxylase major
BH373_RS01000	COG2081	HI0933 family
BH373_RS01010	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BH373_RS01020	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BH373_RS01025	COG0509	glycine decarboxylation via glycine cleavage system
BH373_RS01030	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BH373_RS01030	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BH373_RS01070	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BH373_RS01085	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BH373_RS01095	COG1414	Transcriptional regulator
BH373_RS01100	COG1028	Short-chain dehydrogenase reductase Sdr
BH373_RS01105	COG2031	fatty acid transporter
BH373_RS01110	COG1250	3-hydroxyacyl-CoA dehydrogenase
BH373_RS01120	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BH373_RS01125	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BH373_RS01135	COG4257	antibiotic catabolic process
BH373_RS01155	COG1012	belongs to the aldehyde dehydrogenase family
BH373_RS01160	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BH373_RS01165	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BH373_RS01190	COG1028	Short-chain dehydrogenase reductase Sdr
BH373_RS01200	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BH373_RS01210	COG2188	Transcriptional regulator
BH373_RS01215	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BH373_RS01240	COG0617	tRNA 3'-terminal CCA addition
BH373_RS01255	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BH373_RS01260	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BH373_RS01265	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BH373_RS01270	COG0586	Pfam SNARE associated Golgi protein
BH373_RS01275	COG0860	N-Acetylmuramoyl-L-alanine amidase
BH373_RS01280	COG0802	atpase or kinase
BH373_RS01285	COG0114	fumarate hydratase activity
BH373_RS01295	COG3181	Tripartite tricarboxylate transporter family receptor
BH373_RS01305	COG0405	Gamma-glutamyltransferase
BH373_RS01310	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH373_RS01345	COG1294	oxidase, subunit
BH373_RS01355	COG4988	ABC transporter
BH373_RS01360	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BH373_RS01365	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BH373_RS01405	COG2969	positive regulation of protein catabolic process
BH373_RS01410	COG0625	glutathione transferase activity
BH373_RS01415	COG2857	Cytochrome c1
BH373_RS01420	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BH373_RS01425	COG0723	plastoquinol--plastocyanin reductase activity
BH373_RS01430	COG1970	mechanosensitive ion channel activity
BH373_RS01435	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BH373_RS01450	COG2808	Putative FMN-binding domain
BH373_RS01455	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BH373_RS01460	COG0747	negative chemotaxis
BH373_RS01465	COG0657	acetylesterase activity
BH373_RS01475	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BH373_RS01480	COG2207	Transcriptional regulator
BH373_RS01485	COG0129	dihydroxy-acid dehydratase activity
BH373_RS01490	COG2814	Major facilitator Superfamily
BH373_RS01495	COG0583	DNA-binding transcription factor activity
BH373_RS01505	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
BH373_RS01575	COG1024	Enoyl-CoA hydratase
BH373_RS01580	COG1960	acyl-CoA dehydrogenase activity
BH373_RS01605	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BH373_RS01610	COG0352	thiamine-phosphate diphosphorylase activity
BH373_RS01625	COG1678	Uncharacterized ACR, COG1678
BH373_RS01630	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BH373_RS01635	COG0540	Belongs to the ATCase OTCase family
BH373_RS01650	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BH373_RS01660	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BH373_RS01695	COG1234	tRNA 3'-trailer cleavage
BH373_RS01710	COG3064	Membrane
BH373_RS01740	COG1683	Conserved Protein
BH373_RS01745	COG1120	ATPase activity
BH373_RS01750	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BH373_RS01755	COG4558	Periplasmic binding protein
BH373_RS01760	COG3720	iron ion transport
BH373_RS01770	COG3712	iron ion homeostasis
BH373_RS01775	COG1595	DNA-templated transcription, initiation
BH373_RS01810	COG1802	Transcriptional regulator
BH373_RS01820	COG3069	C4-dicarboxylate transmembrane transporter activity
BH373_RS01830	COG1012	belongs to the aldehyde dehydrogenase family
BH373_RS01865	COG2860	membrane
BH373_RS01870	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BH373_RS01875	COG0708	Exodeoxyribonuclease III
BH373_RS01880	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BH373_RS01885	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BH373_RS01890	COG0154	amidase activity
BH373_RS01895	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BH373_RS01900	COG1077	Cell shape determining protein MreB Mrl
BH373_RS01905	COG1792	Involved in formation and maintenance of cell shape
BH373_RS01915	COG0768	penicillin binding
BH373_RS01920	COG0772	Belongs to the SEDS family
BH373_RS01925	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BH373_RS01930	COG0471	metal ion transport
BH373_RS01935	COG1309	transcriptional regulator
BH373_RS01945	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BH373_RS01960	COG2823	Periplasmic or secreted lipoprotein
BH373_RS01965	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BH373_RS01980	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BH373_RS02000	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH373_RS02010	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH373_RS02035	COG0492	ferredoxin-NADP+ reductase activity
BH373_RS02050	COG3181	Tripartite tricarboxylate transporter family receptor
BH373_RS02055	COG1024	Enoyl-CoA hydratase
BH373_RS02055	COG1250	3-hydroxyacyl-CoA dehydrogenase
BH373_RS02060	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH373_RS02065	COG0028	Belongs to the TPP enzyme family
BH373_RS02090	COG3181	Tripartite tricarboxylate transporter family receptor
BH373_RS02100	COG0697	spore germination
BH373_RS02125	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BH373_RS02130	COG0463	Glycosyl transferase, family 2
BH373_RS02145	COG0786	glutamate:sodium symporter activity
BH373_RS02155	COG2031	fatty acid transporter
BH373_RS02170	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BH373_RS02185	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BH373_RS02200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BH373_RS02210	COG1285	pathogenesis
BH373_RS02215	COG1253	flavin adenine dinucleotide binding
BH373_RS02220	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH373_RS02225	COG1024	Enoyl-CoA hydratase
BH373_RS02230	COG3181	Tripartite tricarboxylate transporter family receptor
BH373_RS02235	COG0583	DNA-binding transcription factor activity
BH373_RS02240	COG1960	acyl-CoA dehydrogenase activity
BH373_RS02250	COG0183	Belongs to the thiolase family
BH373_RS02270	COG0583	DNA-binding transcription factor activity
BH373_RS02275	COG1278	Cold shock
BH373_RS02285	COG1802	Transcriptional regulator
BH373_RS02290	COG1012	belongs to the aldehyde dehydrogenase family
BH373_RS02295	COG2031	fatty acid transporter
BH373_RS02300	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BH373_RS02300	COG1017	nitric oxide dioxygenase activity
BH373_RS02305	COG0251	oxidation-reduction process
BH373_RS02330	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH373_RS02340	COG0583	DNA-binding transcription factor activity
BH373_RS02345	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH373_RS02355	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
BH373_RS02360	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BH373_RS02365	COG0546	phosphoglycolate phosphatase activity
BH373_RS02375	COG1530	ribonuclease E activity
BH373_RS02395	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BH373_RS02400	COG0159	tryptophan synthase activity
BH373_RS02405	COG0133	tryptophan synthase activity
BH373_RS02415	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BH373_RS02420	COG3228	Belongs to the MtfA family
BH373_RS02430	COG0251	oxidation-reduction process
BH373_RS02435	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BH373_RS02440	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BH373_RS02455	COG2878	Part of a membrane complex involved in electron transport
BH373_RS02460	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BH373_RS02495	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BH373_RS02515	COG1268	BioY protein
BH373_RS02520	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BH373_RS02525	COG1122	ATPase activity
BH373_RS02530	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BH373_RS02545	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BH373_RS02550	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BH373_RS02560	COG1196	nuclear chromosome segregation
BH373_RS02565	COG0477	Major facilitator Superfamily
BH373_RS02570	COG1573	uracil-dna glycosylase
BH373_RS02575	COG1214	PFAM Peptidase M22, glycoprotease
BH373_RS02580	COG0745	RESPONSE REGULATOR receiver
BH373_RS02595	COG0450	alkyl hydroperoxide reductase
BH373_RS02600	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BH373_RS02610	COG2223	nitrite transmembrane transporter activity
BH373_RS02625	COG2186	Transcriptional regulator
BH373_RS02645	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BH373_RS02655	COG0583	DNA-binding transcription factor activity
BH373_RS02665	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BH373_RS02670	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BH373_RS02675	COG0137	argininosuccinate synthase activity
BH373_RS02680	COG3158	transport of potassium into the cell
BH373_RS02685	COG0642	Histidine kinase
BH373_RS02715	COG0776	regulation of translation
BH373_RS02720	COG3128	pkhd-type hydroxylase
BH373_RS02730	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BH373_RS02735	COG0557	exoribonuclease II activity
BH373_RS02760	COG0679	Auxin Efflux Carrier
BH373_RS02765	COG2391	methyltransferase activity
BH373_RS02770	COG0069	glutamate synthase activity
BH373_RS02780	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BH373_RS02790	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
BH373_RS02830	COG3706	GGDEF domain
BH373_RS02850	COG0583	DNA-binding transcription factor activity
BH373_RS02860	COG1053	succinate dehydrogenase
BH373_RS02880	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BH373_RS02885	COG0459	protein refolding
BH373_RS02890	COG3468	outer membrane autotransporter barrel domain protein
BH373_RS02905	COG1252	NADH dehydrogenase
BH373_RS02910	COG0284	orotidine-5'-phosphate decarboxylase activity
BH373_RS02915	COG1058	Belongs to the CinA family
BH373_RS02915	COG1546	Belongs to the CinA family
BH373_RS02920	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BH373_RS02930	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BH373_RS02935	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BH373_RS02975	COG3639	organic phosphonate transmembrane transporter activity
BH373_RS02980	COG3639	organic phosphonate transmembrane transporter activity
BH373_RS03000	COG0742	ribosomal rna small subunit methyltransferase
BH373_RS03005	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BH373_RS03010	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BH373_RS03015	COG3135	benzoate transporter
BH373_RS03030	COG0640	Transcriptional regulator
BH373_RS03060	COG4172	Belongs to the ABC transporter superfamily
BH373_RS03065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BH373_RS03070	COG0601	transmembrane transport
BH373_RS03080	COG0280	phosphate acetyltransferase
BH373_RS03080	COG0281	malic enzyme
BH373_RS03140	COG0583	DNA-binding transcription factor activity
BH373_RS03150	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BH373_RS03155	COG0167	dihydroorotate dehydrogenase activity
BH373_RS03175	COG1414	Transcriptional regulator
BH373_RS03180	COG1546	Belongs to the CinA family
BH373_RS03180	COG1058	Belongs to the CinA family
BH373_RS03200	COG0513	Belongs to the DEAD box helicase family
BH373_RS03230	COG0429	hydrolase of the alpha beta-hydrolase fold
BH373_RS03235	COG4783	chaperone-mediated protein folding
BH373_RS03250	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BH373_RS03275	COG0006	proline dipeptidase activity
BH373_RS03285	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BH373_RS03305	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BH373_RS03310	COG0632	four-way junction helicase activity
BH373_RS03325	COG2255	four-way junction helicase activity
BH373_RS03330	COG0514	ATP-dependent DNA helicase (RecQ)
BH373_RS03345	COG0288	reversible hydration of carbon dioxide
BH373_RS03350	COG0154	amidase activity
BH373_RS03360	COG4211	Belongs to the binding-protein-dependent transport system permease family
BH373_RS03390	COG1464	Belongs to the NlpA lipoprotein family
BH373_RS03535	COG1196	nuclear chromosome segregation
BH373_RS03600	COG2135	peptidase activity
BH373_RS03610	COG0494	nUDIX hydrolase
BH373_RS03615	COG0442	prolyl-tRNA aminoacylation
BH373_RS03620	COG0824	Thioesterase
BH373_RS03625	COG0811	peptide transport
BH373_RS03630	COG0848	biopolymer transport protein
BH373_RS03640	COG0823	Involved in the tonB-independent uptake of proteins
BH373_RS03655	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BH373_RS03660	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BH373_RS03690	COG0700	Nucleoside recognition
BH373_RS03695	COG0469	pyruvate kinase activity
BH373_RS03700	COG1929	Belongs to the glycerate kinase type-1 family
BH373_RS03705	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BH373_RS03710	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BH373_RS03715	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BH373_RS03725	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BH373_RS03735	COG2154	pterin-4-alpha-carbinolamine dehydratase
BH373_RS03760	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BH373_RS03765	COG0154	amidase activity
BH373_RS03775	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BH373_RS03780	COG0601	transmembrane transport
BH373_RS03785	COG0747	negative chemotaxis
BH373_RS03805	COG0019	diaminopimelate decarboxylase activity
BH373_RS03825	COG2353	YceI-like domain
BH373_RS03830	COG4774	siderophore transport
BH373_RS03835	COG3712	iron ion homeostasis
BH373_RS03875	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BH373_RS03880	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BH373_RS03885	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BH373_RS03890	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BH373_RS03900	COG0142	geranyltranstransferase activity
BH373_RS03910	COG0583	DNA-binding transcription factor activity
BH373_RS03920	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
BH373_RS03925	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BH373_RS03940	COG2994	toxin metabolic process
BH373_RS03950	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
BH373_RS03955	COG2274	protein secretion by the type I secretion system
BH373_RS03960	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BH373_RS03965	COG1538	Outer membrane efflux protein
BH373_RS03985	COG0765	amino acid transport
BH373_RS03990	COG1126	abc transporter atp-binding protein
BH373_RS04010	COG1028	Short-chain dehydrogenase reductase Sdr
BH373_RS04020	COG1802	Transcriptional regulator
BH373_RS04030	COG1802	Transcriptional regulator
BH373_RS04040	COG0318	PFAM AMP-dependent synthetase and ligase
BH373_RS04050	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BH373_RS04070	COG0028	Belongs to the TPP enzyme family
BH373_RS04100	COG0308	aminopeptidase N
BH373_RS04105	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BH373_RS04115	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BH373_RS04120	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BH373_RS04125	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BH373_RS04130	COG0560	Phosphoserine phosphatase
BH373_RS04135	COG0583	DNA-binding transcription factor activity
BH373_RS04140	COG3181	Tripartite tricarboxylate transporter family receptor
BH373_RS04145	COG0028	Belongs to the TPP enzyme family
BH373_RS04160	COG4774	siderophore transport
BH373_RS04165	COG4774	siderophore transport
BH373_RS04175	COG1007	ATP synthesis coupled electron transport
BH373_RS04190	COG0713	ATP synthesis coupled electron transport
BH373_RS04200	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BH373_RS04205	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BH373_RS04210	COG1034	ATP synthesis coupled electron transport
BH373_RS04220	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BH373_RS04225	COG0649	NAD binding
BH373_RS04230	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BH373_RS04235	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BH373_RS04240	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BH373_RS04245	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BH373_RS04270	COG0671	phosphoesterase, PA-phosphatase related
BH373_RS04280	COG1597	lipid kinase activity
BH373_RS04285	COG0583	DNA-binding transcription factor activity
BH373_RS04290	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BH373_RS04300	COG1733	regulation of RNA biosynthetic process
BH373_RS04305	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BH373_RS04310	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BH373_RS04325	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
BH373_RS04345	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BH373_RS04365	COG3608	succinylglutamate desuccinylase aspartoacylase
BH373_RS04370	COG0626	cystathionine gamma-synthase activity
BH373_RS04375	COG0583	DNA-binding transcription factor activity
BH373_RS04415	COG3799	methylaspartate ammonia-lyase activity
BH373_RS04425	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BH373_RS04435	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BH373_RS04440	COG0149	triose-phosphate isomerase activity
BH373_RS04460	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BH373_RS04475	COG1185	polyribonucleotide nucleotidyltransferase activity
BH373_RS04480	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BH373_RS04490	COG1183	phosphatidylcholine synthase activity
BH373_RS04495	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BH373_RS04500	COG0440	acetolactate synthase activity
BH373_RS04505	COG0028	Belongs to the TPP enzyme family
BH373_RS04520	COG5265	(ABC) transporter
BH373_RS04525	COG0500	methyltransferase
BH373_RS04540	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
BH373_RS04570	COG0511	ligase activity, forming carbon-carbon bonds
BH373_RS04595	COG2188	Transcriptional regulator
BH373_RS04600	COG0439	Biotin carboxylase
BH373_RS04650	COG5265	(ABC) transporter
BH373_RS04660	COG0667	Aldo Keto reductase
BH373_RS04675	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BH373_RS04710	COG0583	DNA-binding transcription factor activity
BH373_RS04735	COG2814	Major facilitator Superfamily
BH373_RS04745	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BH373_RS04760	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BH373_RS04770	COG0287	Prephenate dehydrogenase
BH373_RS04775	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BH373_RS04780	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BH373_RS04800	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BH373_RS04805	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BH373_RS04810	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BH373_RS04830	COG2951	lytic endotransglycosylase activity
BH373_RS04835	COG0123	including yeast histone deacetylase and acetoin utilization protein
BH373_RS04850	COG1960	acyl-CoA dehydrogenase activity
BH373_RS04855	COG0450	alkyl hydroperoxide reductase
BH373_RS04880	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BH373_RS04915	COG0335	large ribosomal subunit rRNA binding
BH373_RS04930	COG0667	Aldo Keto reductase
BH373_RS04945	COG3161	chorismate lyase activity
BH373_RS04950	COG1187	pseudouridine synthase activity
BH373_RS04980	COG1999	signal sequence binding
BH373_RS04985	COG0339	signal peptide processing
BH373_RS04990	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BH373_RS04995	COG4566	intracellular signal transduction
BH373_RS05005	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BH373_RS05010	COG0508	dehydrogenase complex catalyzes the overall conversion of
BH373_RS05015	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BH373_RS05020	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BH373_RS05030	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BH373_RS05035	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BH373_RS05040	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BH373_RS05045	COG0126	phosphoglycerate kinase activity
BH373_RS05050	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BH373_RS05055	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BH373_RS05070	COG0625	glutathione transferase activity
BH373_RS05100	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BH373_RS05110	COG0521	Mo-molybdopterin cofactor biosynthetic process
BH373_RS05120	COG0739	heme binding
BH373_RS05130	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BH373_RS05165	COG0745	RESPONSE REGULATOR receiver
BH373_RS05180	COG0840	transmembrane signaling receptor activity
BH373_RS05190	COG2201	protein-glutamate methylesterase activity
BH373_RS05195	COG0745	RESPONSE REGULATOR receiver
BH373_RS05200	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
BH373_RS05225	COG0667	Aldo Keto reductase
BH373_RS05235	COG4535	Mg2 and Co2 transporter CorC
BH373_RS05240	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BH373_RS05245	COG1702	phosphate starvation-inducible protein PhoH
BH373_RS05250	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BH373_RS05265	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BH373_RS05270	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BH373_RS05275	COG1862	Preprotein translocase
BH373_RS05280	COG0343	queuine tRNA-ribosyltransferase activity
BH373_RS05285	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BH373_RS05290	COG2027	D-alanyl-D-alanine carboxypeptidase
BH373_RS05295	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BH373_RS05305	COG3468	outer membrane autotransporter barrel domain protein
BH373_RS05310	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BH373_RS05310	COG1648	precorrin-2 dehydrogenase activity
BH373_RS05335	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BH373_RS05340	COG0741	lytic transglycosylase activity
BH373_RS05345	COG0436	Aminotransferase
BH373_RS05355	COG0281	malic enzyme
BH373_RS05355	COG0280	phosphate acetyltransferase
BH373_RS05365	COG2732	(Barnase) inhibitor
BH373_RS05380	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BH373_RS05405	COG0248	Ppx GppA phosphatase
BH373_RS05415	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BH373_RS05425	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BH373_RS05430	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BH373_RS05435	COG1534	Rna-binding protein
BH373_RS05460	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BH373_RS05475	COG1295	ribonuclease BN
BH373_RS05485	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BH373_RS05490	COG0745	RESPONSE REGULATOR receiver
BH373_RS05495	COG2205	protein histidine kinase activity
BH373_RS05530	COG1022	Amp-dependent synthetase and ligase
BH373_RS05545	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BH373_RS05550	COG1028	Short-chain dehydrogenase reductase Sdr
BH373_RS05560	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BH373_RS05575	COG1136	(ABC) transporter
BH373_RS05580	COG0084	hydrolase, TatD family'
BH373_RS05615	COG0613	PHP domain protein
BH373_RS05630	COG3539	Fimbrial protein
BH373_RS05635	COG0281	malic enzyme
BH373_RS05635	COG0280	phosphate acetyltransferase
BH373_RS05645	COG1522	sequence-specific DNA binding
BH373_RS05660	COG0567	Dehydrogenase, E1 component
BH373_RS05665	COG0508	dehydrogenase complex catalyzes the overall conversion of
BH373_RS05670	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BH373_RS05675	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BH373_RS05680	COG1028	Short-chain dehydrogenase reductase Sdr
BH373_RS05685	COG0583	DNA-binding transcription factor activity
BH373_RS05695	COG3181	Tripartite tricarboxylate transporter family receptor
BH373_RS05715	COG0180	Tryptophanyl-tRNA synthetase
BH373_RS05720	COG2183	response to ionizing radiation
BH373_RS05725	COG1199	ATP-dependent helicase activity
BH373_RS05735	COG0564	pseudouridine synthase activity
BH373_RS05745	COG3243	poly(R)-hydroxyalkanoic acid synthase
BH373_RS05750	COG1028	Short-chain dehydrogenase reductase Sdr
BH373_RS05755	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
BH373_RS05770	COG0672	)-iron permease
BH373_RS05815	COG0583	DNA-binding transcription factor activity
BH373_RS05825	COG2814	Major facilitator Superfamily
BH373_RS05840	COG1619	proteins homologs of microcin C7 resistance protein MccF
BH373_RS05855	COG2084	Dehydrogenase
BH373_RS05860	COG3181	Tripartite tricarboxylate transporter family receptor
BH373_RS05885	COG2988	succinylglutamate desuccinylase activity
BH373_RS05910	COG0765	amino acid transport
BH373_RS05915	COG0765	amino acid transport
BH373_RS05920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BH373_RS05955	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BH373_RS05960	COG1595	DNA-templated transcription, initiation
BH373_RS05970	COG3530	Putative quorum-sensing-regulated virulence factor
BH373_RS05975	COG0494	nUDIX hydrolase
BH373_RS05990	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BH373_RS05995	COG0542	response to heat
BH373_RS06010	COG3468	outer membrane autotransporter barrel domain protein
BH373_RS06020	COG5441	Belongs to the UPF0261 family
BH373_RS06025	COG5564	TIM-barrel signal transduction protein
BH373_RS06040	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BH373_RS06055	COG1477	protein flavinylation
BH373_RS06075	COG1131	(ABC) transporter
BH373_RS06080	COG0842	Transport permease protein
BH373_RS06090	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BH373_RS06095	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
BH373_RS06095	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
BH373_RS06100	COG1562	ergosterol biosynthetic process
BH373_RS06105	COG1562	ergosterol biosynthetic process
BH373_RS06110	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BH373_RS06115	COG1028	Short-chain dehydrogenase reductase Sdr
BH373_RS06135	COG2304	oxidoreductase activity
BH373_RS06155	COG0534	Mate efflux family protein
BH373_RS06165	COG0254	rRNA binding
BH373_RS06170	COG3483	tryptophan 2,3-dioxygenase activity
BH373_RS06175	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BH373_RS06180	COG2003	Belongs to the UPF0758 family
BH373_RS06185	COG1047	Peptidyl-prolyl cis-trans
BH373_RS06190	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BH373_RS06195	COG0625	glutathione transferase activity
BH373_RS06215	COG0523	cobalamin synthesis protein
BH373_RS06225	COG0583	DNA-binding transcription factor activity
BH373_RS06235	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BH373_RS06240	COG1187	pseudouridine synthase activity
BH373_RS06245	COG0779	Required for maturation of 30S ribosomal subunits
BH373_RS06250	COG2251	uridine kinase activity
BH373_RS06250	COG0195	Participates in both transcription termination and antitermination
BH373_RS06255	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BH373_RS06260	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BH373_RS06265	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BH373_RS06285	COG1611	Belongs to the LOG family
BH373_RS06300	COG0412	Dienelactone hydrolase
BH373_RS06305	COG1283	sodium-dependent phosphate transmembrane transporter activity
BH373_RS06310	COG1760	l-serine dehydratase
BH373_RS06315	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BH373_RS06320	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BH373_RS06330	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BH373_RS06355	COG2311	Membrane
BH373_RS06380	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BH373_RS06400	COG0559	Belongs to the binding-protein-dependent transport system permease family
BH373_RS06415	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BH373_RS06425	COG1653	transport
BH373_RS06430	COG1175	transmembrane transport
BH373_RS06435	COG0395	ABC-type sugar transport system, permease component
BH373_RS06440	COG3842	ATPase activity
BH373_RS06465	COG2363	Small membrane protein
BH373_RS06480	COG1464	Belongs to the NlpA lipoprotein family
BH373_RS06490	COG0688	phosphatidylethanolamine metabolic process
BH373_RS06520	COG0625	glutathione transferase activity
BH373_RS06525	COG0386	Belongs to the glutathione peroxidase family
BH373_RS06545	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH373_RS06575	COG2259	Doxx family
BH373_RS06590	COG0667	Aldo Keto reductase
BH373_RS06620	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BH373_RS06645	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BH373_RS06655	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BH373_RS06710	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BH373_RS06715	COG3568	Endonuclease Exonuclease Phosphatase
BH373_RS06720	COG1695	Transcriptional regulator
BH373_RS06740	COG0583	DNA-binding transcription factor activity
BH373_RS06755	COG1802	Transcriptional regulator
BH373_RS06765	COG3181	Tripartite tricarboxylate transporter family receptor
BH373_RS06775	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH373_RS06790	COG0066	3-isopropylmalate dehydratase activity
BH373_RS06800	COG3181	Tripartite tricarboxylate transporter family receptor
BH373_RS06805	COG4948	Mandelate Racemase Muconate Lactonizing
BH373_RS06820	COG1126	abc transporter atp-binding protein
BH373_RS06830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BH373_RS06870	COG1815	bacterial-type flagellum-dependent cell motility
BH373_RS06875	COG1558	bacterial-type flagellum-dependent cell motility
BH373_RS06885	COG1749	Flagellar hook protein flgE
BH373_RS06900	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BH373_RS06905	COG1706	bacterial-type flagellum-dependent cell motility
BH373_RS06915	COG1256	bacterial-type flagellum assembly
BH373_RS06925	COG0840	transmembrane signaling receptor activity
BH373_RS06930	COG0840	transmembrane signaling receptor activity
BH373_RS06935	COG0840	transmembrane signaling receptor activity
BH373_RS06955	COG1338	Plays a role in the flagellum-specific transport system
BH373_RS06975	COG1580	Controls the rotational direction of flagella during chemotaxis
BH373_RS07005	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BH373_RS07025	COG0559	Belongs to the binding-protein-dependent transport system permease family
BH373_RS07040	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BH373_RS07050	COG1653	transport
BH373_RS07055	COG1175	transmembrane transport
BH373_RS07060	COG0395	ABC-type sugar transport system, permease component
BH373_RS07065	COG3842	ATPase activity
BH373_RS07090	COG2363	Small membrane protein
BH373_RS07105	COG1464	Belongs to the NlpA lipoprotein family
BH373_RS07115	COG0688	phosphatidylethanolamine metabolic process
BH373_RS07145	COG0625	glutathione transferase activity
BH373_RS07150	COG0386	Belongs to the glutathione peroxidase family
BH373_RS07170	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH373_RS07200	COG2259	Doxx family
BH373_RS07215	COG0667	Aldo Keto reductase
BH373_RS07245	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BH373_RS07270	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BH373_RS07280	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BH373_RS07335	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BH373_RS07340	COG3568	Endonuclease Exonuclease Phosphatase
BH373_RS07345	COG1695	Transcriptional regulator
BH373_RS07365	COG0583	DNA-binding transcription factor activity
BH373_RS07380	COG1802	Transcriptional regulator
BH373_RS07390	COG3181	Tripartite tricarboxylate transporter family receptor
BH373_RS07400	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH373_RS07415	COG0066	3-isopropylmalate dehydratase activity
BH373_RS07425	COG3181	Tripartite tricarboxylate transporter family receptor
BH373_RS07430	COG4948	Mandelate Racemase Muconate Lactonizing
BH373_RS07445	COG1126	abc transporter atp-binding protein
BH373_RS07455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BH373_RS07495	COG1815	bacterial-type flagellum-dependent cell motility
BH373_RS07500	COG1558	bacterial-type flagellum-dependent cell motility
BH373_RS07510	COG1749	Flagellar hook protein flgE
BH373_RS07525	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BH373_RS07530	COG1706	bacterial-type flagellum-dependent cell motility
BH373_RS07540	COG1256	bacterial-type flagellum assembly
BH373_RS07550	COG0840	transmembrane signaling receptor activity
BH373_RS07555	COG0840	transmembrane signaling receptor activity
BH373_RS07560	COG0840	transmembrane signaling receptor activity
BH373_RS07580	COG1338	Plays a role in the flagellum-specific transport system
BH373_RS07600	COG1580	Controls the rotational direction of flagella during chemotaxis
BH373_RS07630	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BH373_RS07650	COG0559	Belongs to the binding-protein-dependent transport system permease family
BH373_RS07665	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BH373_RS07675	COG1653	transport
BH373_RS07680	COG1175	transmembrane transport
BH373_RS07685	COG0395	ABC-type sugar transport system, permease component
BH373_RS07690	COG3842	ATPase activity
BH373_RS07715	COG2363	Small membrane protein
BH373_RS07730	COG1464	Belongs to the NlpA lipoprotein family
BH373_RS07740	COG0688	phosphatidylethanolamine metabolic process
BH373_RS07770	COG0625	glutathione transferase activity
BH373_RS07775	COG0386	Belongs to the glutathione peroxidase family
BH373_RS07795	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH373_RS07825	COG2259	Doxx family
BH373_RS07840	COG0667	Aldo Keto reductase
BH373_RS07870	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BH373_RS07895	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BH373_RS07905	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BH373_RS07960	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BH373_RS07965	COG3568	Endonuclease Exonuclease Phosphatase
BH373_RS07970	COG1695	Transcriptional regulator
BH373_RS07990	COG0583	DNA-binding transcription factor activity
BH373_RS08005	COG1802	Transcriptional regulator
BH373_RS08015	COG3181	Tripartite tricarboxylate transporter family receptor
BH373_RS08025	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH373_RS08040	COG0066	3-isopropylmalate dehydratase activity
BH373_RS08050	COG3181	Tripartite tricarboxylate transporter family receptor
BH373_RS08055	COG4948	Mandelate Racemase Muconate Lactonizing
BH373_RS08070	COG1126	abc transporter atp-binding protein
BH373_RS08080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BH373_RS08120	COG1815	bacterial-type flagellum-dependent cell motility
BH373_RS08125	COG1558	bacterial-type flagellum-dependent cell motility
BH373_RS08135	COG1749	Flagellar hook protein flgE
BH373_RS08150	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BH373_RS08155	COG1706	bacterial-type flagellum-dependent cell motility
BH373_RS08165	COG1256	bacterial-type flagellum assembly
BH373_RS08175	COG0840	transmembrane signaling receptor activity
BH373_RS08180	COG0840	transmembrane signaling receptor activity
BH373_RS08185	COG0840	transmembrane signaling receptor activity
BH373_RS08205	COG1338	Plays a role in the flagellum-specific transport system
BH373_RS08225	COG1580	Controls the rotational direction of flagella during chemotaxis
BH373_RS08250	COG1157	protein secretion by the type III secretion system
BH373_RS08260	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BH373_RS08270	COG1677	Flagellar hook-basal body complex protein FliE
BH373_RS08280	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BH373_RS08315	COG0285	dihydrofolate synthase activity
BH373_RS08345	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BH373_RS08350	COG0024	Methionine aminopeptidase
BH373_RS08355	COG0052	Belongs to the universal ribosomal protein uS2 family
BH373_RS08360	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BH373_RS08365	COG0528	UMP kinase activity
BH373_RS08370	COG0233	cytoplasmic translational termination
BH373_RS08375	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BH373_RS08385	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BH373_RS08390	COG0750	zinc metalloprotease
BH373_RS08395	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BH373_RS08400	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
BH373_RS08405	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BH373_RS08410	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BH373_RS08420	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BH373_RS08425	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BH373_RS08430	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BH373_RS08435	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BH373_RS08445	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BH373_RS08445	COG0519	Catalyzes the synthesis of GMP from XMP
BH373_RS08460	COG0330	HflC and HflK could
BH373_RS08465	COG3706	GGDEF domain
BH373_RS08470	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BH373_RS08480	COG2867	negative regulation of translational initiation
BH373_RS08490	COG1960	acyl-CoA dehydrogenase activity
BH373_RS08495	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BH373_RS08525	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BH373_RS08530	COG0505	Belongs to the CarA family
BH373_RS08535	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BH373_RS08545	COG0406	alpha-ribazole phosphatase activity
BH373_RS08555	COG3842	ATPase activity
BH373_RS08575	COG5001	Diguanylate cyclase
BH373_RS08580	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BH373_RS08590	COG1763	Mo-molybdopterin cofactor biosynthetic process
BH373_RS08595	COG0303	'Molybdopterin
BH373_RS08600	COG0746	molybdenum cofactor guanylyltransferase activity
BH373_RS08605	COG0489	protein tyrosine kinase activity
BH373_RS08635	COG3383	formate dehydrogenase (NAD+) activity
BH373_RS08635	COG0243	molybdopterin cofactor binding
BH373_RS08670	COG1122	ATPase activity
BH373_RS08680	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BH373_RS08685	COG0066	3-isopropylmalate dehydratase activity
BH373_RS08690	COG0473	3-isopropylmalate dehydrogenase activity
BH373_RS08695	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BH373_RS08705	COG0101	tRNA pseudouridine synthase activity
BH373_RS08710	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BH373_RS08725	COG0135	phosphoribosylanthranilate isomerase activity
BH373_RS08740	COG3022	response to hydroperoxide
BH373_RS08755	COG3023	N-Acetylmuramoyl-L-alanine amidase
BH373_RS08765	COG0424	maF-like protein
BH373_RS08770	COG1399	metal-binding, possibly nucleic acid-binding protein
BH373_RS08775	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BH373_RS08780	COG0416	fatty acid biosynthetic process
BH373_RS08785	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BH373_RS08800	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BH373_RS08805	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BH373_RS08830	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BH373_RS08835	COG0481	GTPase activity
BH373_RS08840	COG0681	Belongs to the peptidase S26 family
BH373_RS08845	COG0571	ribonuclease III activity
BH373_RS08850	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BH373_RS08855	COG1381	Involved in DNA repair and RecF pathway recombination
BH373_RS08880	COG3181	Tripartite tricarboxylate transporter family receptor
BH373_RS08885	COG0670	Belongs to the BI1 family
BH373_RS08900	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BH373_RS08910	COG0583	DNA-binding transcription factor activity
BH373_RS08925	COG0583	DNA-binding transcription factor activity
BH373_RS08940	COG0791	NLP P60 protein
BH373_RS08950	COG3193	protein, possibly involved in utilization of glycolate and propanediol
BH373_RS08960	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BH373_RS08965	COG0697	spore germination
BH373_RS08970	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
BH373_RS08985	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BH373_RS09015	COG1446	asparaginase
BH373_RS09020	COG4172	Belongs to the ABC transporter superfamily
BH373_RS09025	COG0747	negative chemotaxis
BH373_RS09035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BH373_RS09060	COG0504	CTP synthase activity
BH373_RS09065	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BH373_RS09075	COG0148	phosphopyruvate hydratase activity
BH373_RS09080	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BH373_RS09110	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BH373_RS09120	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BH373_RS09175	COG0039	L-malate dehydrogenase activity
BH373_RS09180	COG2188	Transcriptional regulator
BH373_RS09185	COG2009	succinate dehydrogenase
BH373_RS09190	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BH373_RS09195	COG1053	succinate dehydrogenase
BH373_RS09200	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BH373_RS09205	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BH373_RS09210	COG0372	Belongs to the citrate synthase family
BH373_RS09240	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BH373_RS09245	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BH373_RS09260	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BH373_RS09265	COG3842	ATPase activity
BH373_RS09270	COG1176	ABC-type spermidine putrescine transport system, permease component I
BH373_RS09275	COG1177	transmembrane transport
BH373_RS09300	COG1960	acyl-CoA dehydrogenase activity
BH373_RS09305	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BH373_RS09310	COG0704	Plays a role in the regulation of phosphate uptake
BH373_RS09320	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
BH373_RS09325	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BH373_RS09325	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BH373_RS09330	COG1643	Atp-dependent helicase
BH373_RS09345	COG0438	transferase activity, transferring glycosyl groups
BH373_RS09350	COG0726	polysaccharide deacetylase
BH373_RS09355	COG0463	Glycosyl transferase, family 2
BH373_RS09360	COG0438	transferase activity, transferring glycosyl groups
BH373_RS09365	COG2194	sulfuric ester hydrolase activity
BH373_RS09390	COG0859	PFAM glycosyl transferase family 9
BH373_RS09395	COG1132	(ABC) transporter
BH373_RS09410	COG0077	Prephenate dehydratase
BH373_RS09415	COG1530	ribonuclease E activity
BH373_RS09455	COG3468	outer membrane autotransporter barrel domain protein
BH373_RS09460	COG0424	maF-like protein
BH373_RS09465	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BH373_RS09470	COG0799	negative regulation of ribosome biogenesis
BH373_RS09475	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BH373_RS09480	COG0408	coproporphyrinogen oxidase activity
BH373_RS09485	COG0151	Belongs to the GarS family
BH373_RS09490	COG0217	transcriptional regulatory protein
BH373_RS09495	COG0433	COG0433 Predicted ATPase
BH373_RS09500	COG1115	amino acid carrier protein
BH373_RS09505	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BH373_RS09515	COG1012	belongs to the aldehyde dehydrogenase family
BH373_RS09540	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BH373_RS09555	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BH373_RS09565	COG0747	negative chemotaxis
BH373_RS09575	COG0473	3-isopropylmalate dehydrogenase activity
BH373_RS09580	COG2814	Major facilitator Superfamily
BH373_RS09585	COG1566	PFAM secretion protein HlyD family protein
BH373_RS09595	COG1846	Transcriptional regulator
BH373_RS09605	COG0697	spore germination
BH373_RS09615	COG0501	Belongs to the peptidase M48B family
BH373_RS09635	COG0583	DNA-binding transcription factor activity
BH373_RS09640	COG3842	ATPase activity
BH373_RS09645	COG1178	ABC-type Fe3 transport system permease component
BH373_RS09650	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BH373_RS09655	COG1840	ABC-type Fe3 transport system, periplasmic component
BH373_RS09680	COG2233	PERMEase
BH373_RS09685	COG0840	transmembrane signaling receptor activity
BH373_RS09690	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BH373_RS09720	COG4789	Type iii secretion
BH373_RS09785	COG4669	(LipO)protein
BH373_RS09820	COG4790	Type iii secretion
BH373_RS09825	COG4794	Type iii secretion
BH373_RS09830	COG4791	protein targeting
BH373_RS09835	COG4792	protein secretion
BH373_RS09850	COG1595	DNA-templated transcription, initiation
BH373_RS09875	COG2770	Histidine kinase
BH373_RS09875	COG2208	phosphoserine phosphatase activity
BH373_RS09885	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BH373_RS09890	COG2172	sigma factor antagonist activity
BH373_RS09895	COG1366	Belongs to the anti-sigma-factor antagonist family
BH373_RS09900	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BH373_RS09930	COG2358	TRAP transporter, solute receptor (TAXI family
BH373_RS09935	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BH373_RS09965	COG1017	nitric oxide dioxygenase activity
BH373_RS09965	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BH373_RS09970	COG1959	2 iron, 2 sulfur cluster binding
BH373_RS09975	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BH373_RS09995	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BH373_RS10000	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BH373_RS10005	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BH373_RS10010	COG0084	hydrolase, TatD family'
BH373_RS10025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BH373_RS10035	COG1126	abc transporter atp-binding protein
BH373_RS10045	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BH373_RS10060	COG0028	Belongs to the TPP enzyme family
BH373_RS10080	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BH373_RS10120	COG4336	lyase activity
BH373_RS10130	COG2205	protein histidine kinase activity
BH373_RS10130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BH373_RS10135	COG2197	response regulator
BH373_RS10140	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
BH373_RS10140	COG3064	Membrane
BH373_RS10140	COG3210	domain, Protein
BH373_RS10150	COG3121	Chaperone
BH373_RS10155	COG3188	usher protein
BH373_RS10160	COG3539	Fimbrial protein
BH373_RS10165	COG2831	hemolysin activation secretion protein
BH373_RS10180	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BH373_RS10230	COG0668	transmembrane transport
BH373_RS10255	COG1253	flavin adenine dinucleotide binding
BH373_RS10260	COG1968	undecaprenyl-diphosphatase activity
BH373_RS10265	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BH373_RS10280	COG0215	cysteine-tRNA ligase activity
BH373_RS10290	COG0825	malonyl-CoA metabolic process
BH373_RS10300	COG0037	tRNA processing
BH373_RS10305	COG0527	aspartate kinase activity
BH373_RS10330	COG1250	3-hydroxyacyl-CoA dehydrogenase
BH373_RS10335	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BH373_RS10350	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BH373_RS10355	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
BH373_RS10360	COG1028	Short-chain dehydrogenase reductase Sdr
BH373_RS10370	COG0583	DNA-binding transcription factor activity
BH373_RS10400	COG3842	ATPase activity
BH373_RS10410	COG0446	pyridine nucleotide-disulphide oxidoreductase
BH373_RS10410	COG1902	pentaerythritol trinitrate reductase activity
BH373_RS10415	COG1414	Transcriptional regulator
BH373_RS10420	COG1832	CoA-binding protein
BH373_RS10430	COG0251	oxidation-reduction process
BH373_RS10455	COG1902	pentaerythritol trinitrate reductase activity
BH373_RS10465	COG1215	transferase activity, transferring glycosyl groups
BH373_RS10470	COG0726	polysaccharide deacetylase
BH373_RS10470	COG1649	PFAM Uncharacterised BCR, COG1649
BH373_RS10490	COG1846	Transcriptional regulator
BH373_RS10525	COG2080	2 iron, 2 sulfur cluster binding
BH373_RS10530	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BH373_RS10535	COG3473	Maleate cis-trans isomerase
BH373_RS10545	COG2309	aminopeptidase activity
BH373_RS10550	COG1335	isochorismatase
BH373_RS10565	COG1017	nitric oxide dioxygenase activity
BH373_RS10565	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BH373_RS10580	COG3181	Tripartite tricarboxylate transporter family receptor
BH373_RS10590	COG2197	response regulator
BH373_RS10605	COG0166	Belongs to the GPI family
BH373_RS10610	COG1045	serine acetyltransferase
BH373_RS10620	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BH373_RS10625	COG0483	inositol monophosphate 1-phosphatase activity
BH373_RS10630	COG1012	belongs to the aldehyde dehydrogenase family
BH373_RS10635	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BH373_RS10655	COG0210	DNA helicase
BH373_RS10660	COG0598	Magnesium transport protein CorA
BH373_RS10670	COG0747	negative chemotaxis
BH373_RS10675	COG0601	transmembrane transport
BH373_RS10680	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BH373_RS10685	COG4172	Belongs to the ABC transporter superfamily
BH373_RS10690	COG1846	Transcriptional regulator
BH373_RS10740	COG4964	Belongs to the GSP D family
BH373_RS10780	COG2204	response regulator
BH373_RS10795	COG1595	DNA-templated transcription, initiation
BH373_RS10805	COG3474	cytochrome
BH373_RS10810	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BH373_RS10825	COG3384	dioxygenase
BH373_RS10830	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BH373_RS10855	COG2885	chlorophyll binding
BH373_RS10890	COG0697	spore germination
BH373_RS10895	COG0730	response to heat
BH373_RS10910	COG0583	DNA-binding transcription factor activity
BH373_RS10915	COG0427	acetyl-CoA hydrolase
BH373_RS10970	COG1250	3-hydroxyacyl-CoA dehydrogenase
BH373_RS10975	COG0154	amidase activity
BH373_RS10985	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BH373_RS11000	COG0495	leucyl-tRNA aminoacylation
BH373_RS11005	COG2814	Major facilitator Superfamily
BH373_RS11030	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BH373_RS11035	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BH373_RS11040	COG2814	Major facilitator Superfamily
BH373_RS11060	COG4176	ABC-type proline glycine betaine transport system permease component
BH373_RS11070	COG1942	4-Oxalocrotonate Tautomerase
BH373_RS11075	COG0183	Belongs to the thiolase family
BH373_RS11085	COG1802	Transcriptional regulator
BH373_RS11095	COG1024	Enoyl-CoA hydratase
BH373_RS11110	COG2032	superoxide dismutase activity
BH373_RS11125	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BH373_RS11150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BH373_RS11165	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BH373_RS11170	COG0736	holo-[acyl-carrier-protein] synthase activity
BH373_RS11175	COG1472	Belongs to the glycosyl hydrolase 3 family
BH373_RS11180	COG0322	excinuclease ABC activity
BH373_RS11185	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BH373_RS11200	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BH373_RS11200	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BH373_RS11205	COG2224	Isocitrate lyase
BH373_RS11225	COG0559	Belongs to the binding-protein-dependent transport system permease family
BH373_RS11235	COG4638	Rieske (2fe-2S)
BH373_RS11245	COG1024	Enoyl-CoA hydratase
BH373_RS11255	COG0633	Ferredoxin
BH373_RS11260	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH373_RS11275	COG0183	Belongs to the thiolase family
BH373_RS11290	COG0583	DNA-binding transcription factor activity
BH373_RS11315	COG2346	COG2346, Truncated hemoglobins
BH373_RS11445	COG2207	Transcriptional regulator
BH373_RS11490	COG1132	(ABC) transporter
BH373_RS11515	COG0659	secondary active sulfate transmembrane transporter activity
BH373_RS11545	COG2169	Transcriptional regulator
BH373_RS11550	COG5507	3-demethylubiquinone-9 3-methyltransferase
BH373_RS11555	COG0384	phenazine biosynthesis protein PhzF
BH373_RS11560	COG0583	DNA-binding transcription factor activity
BH373_RS11565	COG2733	membrane
BH373_RS11580	COG1012	belongs to the aldehyde dehydrogenase family
BH373_RS11585	COG3284	Transcriptional regulator
BH373_RS11605	COG1380	Effector of murein hydrolase LrgA
BH373_RS11610	COG4106	trans-aconitate 2-methyltransferase activity
BH373_RS11610	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BH373_RS11620	COG0156	8-amino-7-oxononanoate synthase activity
BH373_RS11690	COG1131	(ABC) transporter
BH373_RS11695	COG0842	Transport permease protein
BH373_RS11700	COG0628	permease
BH373_RS11730	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BH373_RS11740	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BH373_RS11750	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BH373_RS11755	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BH373_RS11760	COG0330	HflC and HflK could
BH373_RS11765	COG0330	HflC and HflK could
BH373_RS11770	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BH373_RS11775	COG1923	regulation of RNA biosynthetic process
BH373_RS11780	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BH373_RS11785	COG1160	GTP binding
BH373_RS11790	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BH373_RS11795	COG2976	Protein conserved in bacteria
BH373_RS11800	COG0124	histidyl-tRNA synthetase
BH373_RS11805	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BH373_RS11815	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BH373_RS11820	COG0105	UTP biosynthetic process
BH373_RS11825	COG0525	valine-tRNA ligase activity
BH373_RS11840	COG0642	Histidine kinase
BH373_RS11860	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BH373_RS11865	COG0336	Belongs to the RNA methyltransferase TrmD family
BH373_RS11870	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BH373_RS11875	COG0228	four-way junction DNA binding
BH373_RS11885	COG0425	Belongs to the sulfur carrier protein TusA family
BH373_RS11890	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BH373_RS11935	COG0154	amidase activity
BH373_RS11940	COG4172	Belongs to the ABC transporter superfamily
BH373_RS11945	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BH373_RS11950	COG0601	transmembrane transport
BH373_RS11955	COG0747	negative chemotaxis
BH373_RS11980	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BH373_RS11990	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BH373_RS12010	COG3395	kinase activity
BH373_RS12025	COG1024	Enoyl-CoA hydratase
BH373_RS12045	COG0633	Ferredoxin
BH373_RS12050	COG0443	Heat shock 70 kDa protein
BH373_RS12055	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BH373_RS12060	COG0316	Belongs to the HesB IscA family
BH373_RS12065	COG0822	iron-sulfur transferase activity
BH373_RS12070	COG1104	cysteine desulfurase activity
BH373_RS12080	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BH373_RS12085	COG0556	nucleotide-excision repair
BH373_RS12095	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BH373_RS12125	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BH373_RS12145	COG1028	Short-chain dehydrogenase reductase Sdr
BH373_RS12150	COG0183	Belongs to the thiolase family
BH373_RS12160	COG1024	Enoyl-CoA hydratase
BH373_RS12175	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH373_RS12180	COG0583	DNA-binding transcription factor activity
BH373_RS12185	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BH373_RS12190	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BH373_RS12195	COG0740	serine-type endopeptidase activity
BH373_RS12200	COG0544	peptidyl-prolyl cis-trans isomerase activity
BH373_RS12210	COG1278	Cold shock
BH373_RS12220	COG1278	Cold shock
BH373_RS12255	COG2171	N-acyltransferase activity
BH373_RS12260	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BH373_RS12265	COG2890	protein-(glutamine-N5) methyltransferase activity
BH373_RS12270	COG0488	(ABC) transporter
BH373_RS12275	COG4771	TonB-dependent receptor
BH373_RS12280	COG0210	DNA helicase
BH373_RS12300	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BH373_RS12305	COG0196	riboflavin kinase activity
BH373_RS12310	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BH373_RS12315	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BH373_RS12320	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BH373_RS12330	COG1522	sequence-specific DNA binding
BH373_RS12345	COG2951	lytic endotransglycosylase activity
BH373_RS12350	COG2833	Protein of unknown function (DUF455)
BH373_RS12370	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BH373_RS12370	COG0189	ligase activity
BH373_RS12375	COG1181	Belongs to the D-alanine--D-alanine ligase family
BH373_RS12375	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BH373_RS12380	COG3237	CsbD-like
BH373_RS12390	COG2823	Periplasmic or secreted lipoprotein
BH373_RS12410	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BH373_RS12415	COG0584	glycerophosphoryl diester phosphodiesterase
BH373_RS12420	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BH373_RS12430	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BH373_RS12430	COG0678	peroxiredoxin activity
BH373_RS12440	COG0789	Transcriptional regulator
BH373_RS12445	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BH373_RS12475	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BH373_RS12480	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BH373_RS12490	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BH373_RS12495	COG2252	PERMEase
BH373_RS12505	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BH373_RS12540	COG0488	(ABC) transporter
BH373_RS12545	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BH373_RS12560	COG1024	Enoyl-CoA hydratase
BH373_RS12565	COG1619	proteins homologs of microcin C7 resistance protein MccF
BH373_RS12570	COG0590	tRNA wobble adenosine to inosine editing
BH373_RS12595	COG2212	antiporter activity
BH373_RS12600	COG1863	multisubunit Na H antiporter MnhE subunit
BH373_RS12605	COG0651	ATP synthesis coupled electron transport
BH373_RS12610	COG1006	Multisubunit Na H antiporter MnhC subunit
BH373_RS12615	COG2111	Na H antiporter
BH373_RS12615	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BH373_RS12635	COG0583	DNA-binding transcription factor activity
BH373_RS12640	COG1028	Short-chain dehydrogenase reductase Sdr
BH373_RS12670	COG0431	NADPH-dependent FMN reductase
BH373_RS12715	COG1028	Short-chain dehydrogenase reductase Sdr
BH373_RS12720	COG0179	Fumarylacetoacetate (FAA) hydrolase
BH373_RS12750	COG0625	glutathione transferase activity
BH373_RS12760	COG2944	sequence-specific DNA binding
BH373_RS12770	COG2197	response regulator
BH373_RS12795	COG3119	arylsulfatase activity
BH373_RS12825	COG0714	Associated with various cellular activities
BH373_RS12845	COG1028	Short-chain dehydrogenase reductase Sdr
BH373_RS12850	COG0861	Integral membrane protein TerC family
BH373_RS12895	COG0300	oxidoreductase activity
BH373_RS12920	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BH373_RS12935	COG0438	transferase activity, transferring glycosyl groups
BH373_RS12970	COG0783	Belongs to the Dps family
BH373_RS12985	COG0583	DNA-binding transcription factor activity
BH373_RS12990	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BH373_RS13005	COG0656	L-ascorbic acid biosynthetic process
BH373_RS13015	COG0583	DNA-binding transcription factor activity
BH373_RS13025	COG1840	ABC-type Fe3 transport system, periplasmic component
BH373_RS13030	COG1178	ABC-type Fe3 transport system permease component
BH373_RS13035	COG3842	ATPase activity
BH373_RS13045	COG1741	Belongs to the pirin family
BH373_RS13050	COG1741	Belongs to the pirin family
BH373_RS13055	COG0583	DNA-binding transcription factor activity
BH373_RS13060	COG2204	response regulator
BH373_RS13070	COG0174	glutamine synthetase
BH373_RS13075	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BH373_RS13085	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BH373_RS13090	COG2200	EAL domain
BH373_RS13090	COG2199	diguanylate cyclase activity
BH373_RS13115	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BH373_RS13120	COG1561	YicC-like family, N-terminal region
BH373_RS13140	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BH373_RS13145	COG0791	NLP P60 protein
BH373_RS13150	COG1028	Short-chain dehydrogenase reductase Sdr
BH373_RS13155	COG2863	cytochrome
BH373_RS13160	COG3258	Cytochrome c
BH373_RS13165	COG0194	GDP metabolic process
BH373_RS13170	COG1758	RNA polymerase activity
BH373_RS13175	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BH373_RS13180	COG1126	abc transporter atp-binding protein
BH373_RS13185	COG0765	amino acid transport
BH373_RS13190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BH373_RS13205	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BH373_RS13210	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BH373_RS13215	COG3539	Fimbrial protein
BH373_RS13220	COG2850	peptidyl-arginine hydroxylation
BH373_RS13225	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BH373_RS13230	COG3360	Dodecin
BH373_RS13270	COG0009	L-threonylcarbamoyladenylate synthase
BH373_RS13275	COG2321	neutral zinc metallopeptidase
BH373_RS13295	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BH373_RS13300	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BH373_RS13305	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BH373_RS13315	COG1074	ATP-dependent DNA helicase activity
BH373_RS13325	COG2814	Major facilitator Superfamily
BH373_RS13335	COG1686	Belongs to the peptidase S11 family
BH373_RS13350	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BH373_RS13355	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BH373_RS13360	COG4974	Belongs to the 'phage' integrase family
BH373_RS13365	COG0583	DNA-binding transcription factor activity
BH373_RS13370	COG0028	Belongs to the TPP enzyme family
BH373_RS13385	COG0028	Belongs to the TPP enzyme family
BH373_RS13390	COG1126	abc transporter atp-binding protein
BH373_RS13395	COG0765	amino acid transport
BH373_RS13410	COG1414	Transcriptional regulator
BH373_RS13415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BH373_RS13420	COG0009	L-threonylcarbamoyladenylate synthase
BH373_RS13425	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BH373_RS13430	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BH373_RS13435	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BH373_RS13440	COG2944	sequence-specific DNA binding
BH373_RS13450	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BH373_RS13505	COG1126	abc transporter atp-binding protein
BH373_RS13510	COG0765	amino acid transport
BH373_RS13515	COG0765	amino acid transport
BH373_RS13520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BH373_RS13530	COG2423	ornithine cyclodeaminase activity
BH373_RS13540	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BH373_RS13545	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BH373_RS13555	COG0189	ligase activity
BH373_RS13560	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BH373_RS13565	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BH373_RS13570	COG2197	response regulator
BH373_RS13590	COG3706	GGDEF domain
BH373_RS13600	COG1028	Short-chain dehydrogenase reductase Sdr
BH373_RS13615	COG3486	L-lysine 6-monooxygenase (NADPH) activity
BH373_RS13645	COG2814	Major facilitator Superfamily
BH373_RS13665	COG3706	GGDEF domain
BH373_RS13690	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BH373_RS13695	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BH373_RS13700	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BH373_RS13705	COG1674	ftsk spoiiie
BH373_RS13710	COG0492	ferredoxin-NADP+ reductase activity
BH373_RS13715	COG1193	negative regulation of DNA recombination
BH373_RS13730	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BH373_RS13745	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BH373_RS13750	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BH373_RS13755	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
BH373_RS13765	COG0745	RESPONSE REGULATOR receiver
BH373_RS13810	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BH373_RS13830	COG0612	Peptidase, M16
BH373_RS13840	COG0443	Heat shock 70 kDa protein
BH373_RS13850	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BH373_RS13860	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BH373_RS13865	COG1420	regulation of RNA biosynthetic process
BH373_RS13870	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BH373_RS13875	COG0497	DNA recombination
BH373_RS13880	COG0735	belongs to the Fur family
BH373_RS13885	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BH373_RS13890	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BH373_RS13895	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BH373_RS13930	COG0446	pyridine nucleotide-disulphide oxidoreductase
BH373_RS13930	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BH373_RS13935	COG4311	Sarcosine oxidase, delta subunit
BH373_RS13940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BH373_RS13950	COG0583	DNA-binding transcription factor activity
BH373_RS13960	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BH373_RS13990	COG4964	Belongs to the GSP D family
BH373_RS14050	COG0181	hydroxymethylbilane synthase activity
BH373_RS14055	COG0861	Integral membrane protein TerC family
BH373_RS14060	COG0861	Integral membrane protein TerC family
BH373_RS14065	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BH373_RS14070	COG0045	succinate-CoA ligase (ADP-forming) activity
BH373_RS14080	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BH373_RS14090	COG2137	regulation of response to DNA damage stimulus
BH373_RS14095	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BH373_RS14105	COG0642	Histidine kinase
BH373_RS14115	COG1024	Enoyl-CoA hydratase
BH373_RS14115	COG1250	3-hydroxyacyl-CoA dehydrogenase
BH373_RS14120	COG3842	ATPase activity
BH373_RS14135	COG1028	Short-chain dehydrogenase reductase Sdr
BH373_RS14155	COG0583	DNA-binding transcription factor activity
BH373_RS14160	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH373_RS14170	COG2974	May be involved in recombination
BH373_RS14175	COG0540	Belongs to the ATCase OTCase family
BH373_RS14245	COG0776	regulation of translation
BH373_RS14250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BH373_RS14250	COG0072	phenylalanine-tRNA ligase activity
BH373_RS14255	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BH373_RS14260	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BH373_RS14265	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BH373_RS14275	COG0756	dUTP diphosphatase activity
BH373_RS14285	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BH373_RS14300	COG0500	methyltransferase
BH373_RS14310	COG0586	Pfam SNARE associated Golgi protein
BH373_RS14335	COG1609	Transcriptional regulator
BH373_RS14340	COG4172	Belongs to the ABC transporter superfamily
BH373_RS14350	COG0601	transmembrane transport
BH373_RS14355	COG0747	negative chemotaxis
BH373_RS14370	COG1280	lysine exporter protein (LysE YggA)
BH373_RS14385	COG2814	Major facilitator Superfamily
BH373_RS14415	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BH373_RS14430	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BH373_RS14465	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BH373_RS14470	COG1116	anion transmembrane transporter activity
BH373_RS14480	COG1228	amidohydrolase
BH373_RS14495	COG0477	Major facilitator Superfamily
BH373_RS14505	COG3550	peptidyl-serine autophosphorylation
BH373_RS14515	COG0519	Catalyzes the synthesis of GMP from XMP
BH373_RS14515	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BH373_RS14565	COG0420	3'-5' exonuclease activity
BH373_RS14570	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BH373_RS14600	COG0395	ABC-type sugar transport system, permease component
BH373_RS14640	COG3181	Tripartite tricarboxylate transporter family receptor
BH373_RS14675	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BH373_RS14700	COG0602	queuosine metabolic process
BH373_RS14705	COG0720	synthase
BH373_RS14710	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BH373_RS14715	COG0235	Class ii aldolase
BH373_RS14740	COG3064	Membrane
BH373_RS14740	COG3210	domain, Protein
BH373_RS14740	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
BH373_RS14745	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BH373_RS14745	COG0047	phosphoribosylformylglycinamidine synthase activity
BH373_RS14750	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BH373_RS14755	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BH373_RS14760	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BH373_RS14775	COG3539	Fimbrial protein
BH373_RS14785	COG2050	protein possibly involved in aromatic compounds catabolism
BH373_RS14790	COG1024	Enoyl-CoA hydratase
BH373_RS14795	COG1012	belongs to the aldehyde dehydrogenase family
BH373_RS14805	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BH373_RS14810	COG2151	metal-sulfur cluster biosynthetic enzyme
BH373_RS14815	COG3396	Phenylacetate-CoA oxygenase
BH373_RS14820	COG3460	Phenylacetate-CoA oxygenase
BH373_RS14825	COG3396	Phenylacetate-CoA oxygenase
BH373_RS14830	COG3327	negative regulation of DNA-templated transcription, initiation
BH373_RS14840	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BH373_RS14845	COG0501	Belongs to the peptidase M48B family
BH373_RS14850	COG1162	GTPase activity
BH373_RS14860	COG0601	transmembrane transport
BH373_RS14865	COG0747	negative chemotaxis
BH373_RS14910	COG0668	transmembrane transport
BH373_RS14915	COG0165	Argininosuccinate lyase
BH373_RS14935	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BH373_RS14940	COG0303	'Molybdopterin
BH373_RS14945	COG0521	Mo-molybdopterin cofactor biosynthetic process
BH373_RS14960	COG0315	cyclic pyranopterin monophosphate synthase activity
BH373_RS14970	COG0412	Dienelactone hydrolase
BH373_RS14980	COG0678	peroxiredoxin activity
BH373_RS14990	COG0697	spore germination
BH373_RS14995	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BH373_RS15020	COG0789	Transcriptional regulator
BH373_RS15040	COG1028	Short-chain dehydrogenase reductase Sdr
BH373_RS15050	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BH373_RS15055	COG1845	cytochrome c oxidase, subunit III
BH373_RS15060	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BH373_RS15070	COG0477	Major facilitator Superfamily
BH373_RS15100	COG3468	outer membrane autotransporter barrel domain protein
BH373_RS15105	COG1309	transcriptional regulator
BH373_RS15110	COG2271	Major facilitator Superfamily
BH373_RS15145	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BH373_RS15145	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BH373_RS15145	COG0506	proline dehydrogenase activity
BH373_RS15155	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BH373_RS15155	COG3008	intermembrane lipid transfer
BH373_RS15160	COG2995	paraquat-inducible protein a
BH373_RS15165	COG0542	response to heat
BH373_RS15170	COG4953	penicillin-binding protein 1C
BH373_RS15180	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BH373_RS15185	COG1278	Cold shock
BH373_RS15195	COG0183	Belongs to the thiolase family
BH373_RS15200	COG0038	chloride channel
BH373_RS15205	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BH373_RS15210	COG1570	exodeoxyribonuclease VII activity
BH373_RS15220	COG0811	peptide transport
BH373_RS15225	COG0848	biopolymer transport protein
BH373_RS15230	COG1663	tetraacyldisaccharide 4'-kinase activity
BH373_RS15235	COG2835	tetraacyldisaccharide 4'-kinase activity
BH373_RS15240	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BH373_RS15245	COG0563	adenylate kinase activity
BH373_RS15255	COG0728	peptidoglycan biosynthetic process
BH373_RS15265	COG0268	Binds directly to 16S ribosomal RNA
BH373_RS15295	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BH373_RS15320	COG0436	Aminotransferase
BH373_RS15325	COG3737	Protein of unknown function (DUF498/DUF598)
BH373_RS15330	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BH373_RS15335	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BH373_RS15340	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BH373_RS15350	COG0305	Participates in initiation and elongation during chromosome replication
BH373_RS15360	COG0359	binds to the 23S rRNA
BH373_RS15365	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BH373_RS15370	COG2965	DNA replication, synthesis of RNA primer
BH373_RS15375	COG0360	Binds together with S18 to 16S ribosomal RNA
BH373_RS15380	COG1469	GTP cyclohydrolase I activity
BH373_RS15385	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BH373_RS15390	COG0142	geranyltranstransferase activity
BH373_RS15395	COG1722	exodeoxyribonuclease VII activity
BH373_RS15405	COG3181	Tripartite tricarboxylate transporter family receptor
BH373_RS15425	COG2239	Acts as a magnesium transporter
BH373_RS15435	COG2855	membrane
BH373_RS15445	COG1473	amidohydrolase
BH373_RS15450	COG0318	PFAM AMP-dependent synthetase and ligase
BH373_RS15470	COG1501	Belongs to the glycosyl hydrolase 31 family
BH373_RS15475	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BH373_RS15480	COG2011	ABC-type metal ion transport system permease component
BH373_RS15500	COG1454	alcohol dehydrogenase
BH373_RS15525	COG2186	Transcriptional regulator
BH373_RS15530	COG3181	Tripartite tricarboxylate transporter family receptor
BH373_RS15550	COG1175	transmembrane transport
BH373_RS15555	COG0395	ABC-type sugar transport system, permease component
BH373_RS15560	COG3842	ATPase activity
BH373_RS15575	COG1653	transport
BH373_RS15595	COG2818	Glycosylase
BH373_RS15600	COG2982	Protein involved in outer membrane biogenesis
BH373_RS15610	COG1309	transcriptional regulator
BH373_RS15615	COG1028	Short-chain dehydrogenase reductase Sdr
BH373_RS15655	COG0583	DNA-binding transcription factor activity
BH373_RS15660	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BH373_RS15665	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BH373_RS15680	COG1028	Short-chain dehydrogenase reductase Sdr
BH373_RS15685	COG0477	Major facilitator Superfamily
BH373_RS15695	COG0583	DNA-binding transcription factor activity
BH373_RS15700	COG1448	Aminotransferase
BH373_RS15705	COG1418	mRNA catabolic process
BH373_RS15730	COG1063	alcohol dehydrogenase
BH373_RS15750	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BH373_RS15760	COG0318	PFAM AMP-dependent synthetase and ligase
BH373_RS15770	COG1522	sequence-specific DNA binding
BH373_RS15775	COG3181	Tripartite tricarboxylate transporter family receptor
BH373_RS15780	COG0307	riboflavin synthase, alpha
BH373_RS15785	COG0154	amidase activity
BH373_RS15805	COG2807	transmembrane transport
BH373_RS15810	COG0590	tRNA wobble adenosine to inosine editing
BH373_RS15820	COG0583	DNA-binding transcription factor activity
BH373_RS15855	COG0559	Belongs to the binding-protein-dependent transport system permease family
BH373_RS15860	COG0251	oxidation-reduction process
BH373_RS15875	COG1414	Transcriptional regulator
BH373_RS15880	COG1028	Short-chain dehydrogenase reductase Sdr
BH373_RS15895	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BH373_RS15910	COG1024	Enoyl-CoA hydratase
BH373_RS15915	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH373_RS15960	COG3909	cytochrome
BH373_RS15965	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BH373_RS15970	COG0625	glutathione transferase activity
BH373_RS15975	COG0730	response to heat
BH373_RS15980	COG0482	sulfurtransferase activity
BH373_RS15985	COG0583	DNA-binding transcription factor activity
BH373_RS16020	COG2819	hydrolase of the alpha beta superfamily
BH373_RS16025	COG0247	lactate metabolic process
BH373_RS16030	COG0277	FAD linked oxidase domain protein
BH373_RS16035	COG0277	FAD linked oxidase domain protein
BH373_RS16040	COG0277	FAD linked oxidase domain protein
BH373_RS16045	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
BH373_RS16045	COG3210	domain, Protein
BH373_RS16045	COG3064	Membrane
BH373_RS16045	COG3210	domain, Protein
BH373_RS16045	COG3064	Membrane
BH373_RS16045	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
BH373_RS16050	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BH373_RS16055	COG0312	modulator of DNA gyrase
BH373_RS16090	COG1666	GTP binding
BH373_RS16135	COG3220	belongs to the UPF0276 family
BH373_RS16155	COG0640	Transcriptional regulator
BH373_RS16160	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BH373_RS16165	COG1845	cytochrome c oxidase, subunit III
BH373_RS16170	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BH373_RS16180	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BH373_RS16220	COG0583	DNA-binding transcription factor activity
BH373_RS16250	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BH373_RS16250	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BH373_RS16265	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BH373_RS16270	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BH373_RS16280	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BH373_RS16295	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BH373_RS16300	COG0316	Belongs to the HesB IscA family
BH373_RS16310	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BH373_RS16315	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BH373_RS16320	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BH373_RS16325	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BH373_RS16330	COG0312	modulator of DNA gyrase
BH373_RS16335	COG3028	Belongs to the UPF0307 family
BH373_RS16350	COG1116	anion transmembrane transporter activity
BH373_RS16355	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BH373_RS16360	COG1335	isochorismatase
BH373_RS16365	COG0346	lactoylglutathione lyase activity
BH373_RS16370	COG0513	Belongs to the DEAD box helicase family
BH373_RS16375	COG3069	C4-dicarboxylate transmembrane transporter activity
BH373_RS16380	COG1802	Transcriptional regulator
BH373_RS16390	COG0045	succinate-CoA ligase (ADP-forming) activity
BH373_RS16390	COG1042	CoA-binding domain protein
BH373_RS16390	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BH373_RS16395	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BH373_RS16410	COG1522	sequence-specific DNA binding
BH373_RS16445	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BH373_RS16450	COG1696	Membrane protein involved in D-alanine export
BH373_RS16475	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BH373_RS16490	COG0439	Biotin carboxylase
BH373_RS16495	COG0511	ligase activity, forming carbon-carbon bonds
BH373_RS16500	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BH373_RS16505	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BH373_RS16510	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BH373_RS16515	COG3150	esterase
BH373_RS16520	COG0557	exoribonuclease II activity
BH373_RS16530	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BH373_RS16550	COG1522	sequence-specific DNA binding
BH373_RS16555	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BH373_RS16560	COG1028	Short-chain dehydrogenase reductase Sdr
BH373_RS16580	COG0653	protein targeting
BH373_RS16585	COG0739	heme binding
BH373_RS16595	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BH373_RS16600	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BH373_RS16610	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BH373_RS16615	COG1181	Belongs to the D-alanine--D-alanine ligase family
BH373_RS16620	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BH373_RS16625	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BH373_RS16635	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BH373_RS16640	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BH373_RS16645	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BH373_RS16655	COG3116	cell division
BH373_RS16660	COG0275	rRNA processing
BH373_RS16665	COG2001	Belongs to the MraZ family
BH373_RS16680	COG0418	dihydroorotase activity
BH373_RS16685	COG1473	amidohydrolase
BH373_RS16735	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BH373_RS16740	COG4654	Cytochrome c, class I
BH373_RS16745	COG0129	dihydroxy-acid dehydratase activity
BH373_RS16750	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BH373_RS16800	COG2084	Dehydrogenase
BH373_RS16815	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BH373_RS16820	COG0513	Belongs to the DEAD box helicase family
BH373_RS16830	COG0617	tRNA 3'-terminal CCA addition
BH373_RS16845	COG0477	Major facilitator Superfamily
BH373_RS16855	COG0583	DNA-binding transcription factor activity
BH373_RS16870	COG1950	PFAM Membrane protein of
BH373_RS16875	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BH373_RS16890	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BH373_RS16900	COG1560	Kdo2-lipid A biosynthetic process
BH373_RS16905	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BH373_RS16915	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BH373_RS16925	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
BH373_RS16935	COG0803	Belongs to the bacterial solute-binding protein 9 family
BH373_RS16955	COG0735	belongs to the Fur family
BH373_RS16960	COG0523	cobalamin synthesis protein
BH373_RS16970	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BH373_RS16975	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BH373_RS16985	COG2096	Adenosyltransferase
BH373_RS17000	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BH373_RS17005	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BH373_RS17050	COG4772	TonB-dependent receptor
BH373_RS17080	COG0405	Gamma-glutamyltransferase
BH373_RS17090	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BH373_RS17115	COG1309	transcriptional regulator
BH373_RS17130	COG0745	RESPONSE REGULATOR receiver
BH373_RS17180	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BH373_RS17200	COG0582	viral genome integration into host DNA
BH373_RS17205	COG0012	GTP binding
BH373_RS17215	COG0193	aminoacyl-tRNA hydrolase activity
BH373_RS17220	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BH373_RS17225	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BH373_RS17235	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BH373_RS17240	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BH373_RS17250	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BH373_RS17275	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
BH373_RS17285	COG1368	sulfuric ester hydrolase activity
BH373_RS17290	COG0642	Histidine kinase
BH373_RS17295	COG0745	RESPONSE REGULATOR receiver
BH373_RS17300	COG0277	FAD linked oxidase domain protein
BH373_RS17315	COG0166	Belongs to the GPI family
BH373_RS17320	COG0438	transferase activity, transferring glycosyl groups
BH373_RS17325	COG0438	transferase activity, transferring glycosyl groups
BH373_RS17340	COG0438	transferase activity, transferring glycosyl groups
BH373_RS17355	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BH373_RS17360	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BH373_RS17365	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
BH373_RS17375	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BH373_RS17385	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BH373_RS17400	COG0747	negative chemotaxis
BH373_RS17405	COG0601	transmembrane transport
BH373_RS17410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BH373_RS17430	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BH373_RS17435	COG0830	nickel cation binding
BH373_RS17445	COG0804	urea catabolic process
BH373_RS17450	COG0832	Belongs to the urease beta subunit family
BH373_RS17460	COG0831	urea catabolic process
BH373_RS17465	COG0829	nickel cation binding
BH373_RS17490	COG2188	Transcriptional regulator
BH373_RS17515	COG2719	SpoVR family
BH373_RS17520	COG2718	Belongs to the UPF0229 family
BH373_RS17540	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH373_RS17555	COG1960	acyl-CoA dehydrogenase activity
BH373_RS17605	COG2030	dehydratase
BH373_RS17665	COG0328	RNA-DNA hybrid ribonuclease activity
BH373_RS17670	COG2226	methyltransferase
BH373_RS17675	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BH373_RS17680	COG1388	LysM domain
BH373_RS17680	COG0741	lytic transglycosylase activity
BH373_RS17700	COG2979	Protein of unknown function (DUF533)
BH373_RS17720	COG0745	RESPONSE REGULATOR receiver
BH373_RS17735	COG1271	oxidase subunit
BH373_RS17740	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BH373_RS17745	COG0850	regulation of cytokinetic process
BH373_RS17750	COG2894	cell division
BH373_RS17755	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BH373_RS17785	COG0601	transmembrane transport
BH373_RS17795	COG1215	transferase activity, transferring glycosyl groups
BH373_RS17810	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BH373_RS17820	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BH373_RS17840	COG0318	PFAM AMP-dependent synthetase and ligase
BH373_RS17845	COG2188	Transcriptional regulator
BH373_RS17850	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BH373_RS17855	COG2814	Major facilitator Superfamily
BH373_RS17865	COG0259	pyridoxamine-phosphate oxidase activity
BH373_RS17870	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BH373_RS17885	COG0583	DNA-binding transcription factor activity
BH373_RS17915	COG0134	indole-3-glycerol-phosphate synthase activity
BH373_RS17920	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BH373_RS17925	COG0512	Glutamine amidotransferase of anthranilate synthase
BH373_RS17935	COG0546	phosphoglycolate phosphatase activity
BH373_RS17940	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BH373_RS17945	COG2967	ApaG domain
BH373_RS17950	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
BH373_RS17955	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BH373_RS17960	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BH373_RS17965	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BH373_RS17975	COG0037	tRNA processing
BH373_RS17985	COG3634	alkyl hydroperoxide reductase activity
BH373_RS17990	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BH373_RS17995	COG1024	Enoyl-CoA hydratase
BH373_RS18020	COG0356	it plays a direct role in the translocation of protons across the membrane
BH373_RS18030	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BH373_RS18035	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BH373_RS18040	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BH373_RS18045	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BH373_RS18050	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BH373_RS18055	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BH373_RS18065	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BH373_RS18070	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BH373_RS18075	COG0210	DNA helicase
BH373_RS18085	COG2195	Cleaves the N-terminal amino acid of tripeptides
BH373_RS18100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BH373_RS18105	COG0601	transmembrane transport
BH373_RS18125	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BH373_RS18130	COG1024	Enoyl-CoA hydratase
BH373_RS18135	COG1024	Enoyl-CoA hydratase
BH373_RS18190	COG2132	Multicopper oxidase
BH373_RS18200	COG1024	Enoyl-CoA hydratase
BH373_RS18200	COG1250	3-hydroxyacyl-CoA dehydrogenase
BH373_RS18225	COG0154	amidase activity
BH373_RS18255	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BH373_RS18260	COG3568	Endonuclease Exonuclease Phosphatase
BH373_RS18265	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BH373_RS18300	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BH373_RS18310	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BH373_RS18325	COG1137	ATPase activity
BH373_RS18340	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BH373_RS18345	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BH373_RS18345	COG2010	Cytochrome c
BH373_RS18355	COG1660	Displays ATPase and GTPase activities
BH373_RS18360	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BH373_RS18400	COG3181	Tripartite tricarboxylate transporter family receptor
BH373_RS18410	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BH373_RS18415	COG2890	protein-(glutamine-N5) methyltransferase activity
BH373_RS18420	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BH373_RS18425	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BH373_RS18465	COG1960	acyl-CoA dehydrogenase activity
BH373_RS18475	COG0183	Belongs to the thiolase family
BH373_RS18480	COG1522	sequence-specific DNA binding
BH373_RS18485	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BH373_RS18505	COG1024	Enoyl-CoA hydratase
BH373_RS18520	COG0604	alcohol dehydrogenase
BH373_RS18525	COG2072	flavoprotein involved in K transport
BH373_RS18540	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BH373_RS18550	COG1960	acyl-CoA dehydrogenase activity
BH373_RS18555	COG1960	acyl-CoA dehydrogenase activity
BH373_RS18560	COG0277	FAD linked oxidase domain protein
BH373_RS18570	COG3181	Tripartite tricarboxylate transporter family receptor
BH373_RS18590	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BH373_RS18600	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH373_RS18605	COG3181	Tripartite tricarboxylate transporter family receptor
BH373_RS18610	COG1960	acyl-CoA dehydrogenase activity
BH373_RS18630	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BH373_RS18635	COG1024	Enoyl-CoA hydratase
BH373_RS18640	COG1960	acyl-CoA dehydrogenase activity
BH373_RS18660	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BH373_RS18665	COG0022	dehydrogenase e1 component
BH373_RS18670	COG1024	Enoyl-CoA hydratase
BH373_RS18675	COG0508	dehydrogenase complex catalyzes the overall conversion of
BH373_RS18695	COG0683	leucine binding
BH373_RS18700	COG0559	Belongs to the binding-protein-dependent transport system permease family
BH373_RS18705	COG0411	ABC transporter
BH373_RS18715	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BH373_RS18730	COG3181	Tripartite tricarboxylate transporter family receptor
BH373_RS18755	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BH373_RS18760	COG0793	Belongs to the peptidase S41A family
BH373_RS18765	COG4942	peptidase
BH373_RS18770	COG0588	phosphoglycerate mutase activity
BH373_RS18780	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BH373_RS18785	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BH373_RS18790	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BH373_RS18795	COG3181	Tripartite tricarboxylate transporter family receptor
BH373_RS18810	COG2226	methyltransferase
BH373_RS18815	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
BH373_RS18830	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BH373_RS18835	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BH373_RS18860	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BH373_RS18885	COG1335	isochorismatase
BH373_RS18890	COG2309	aminopeptidase activity
BH373_RS18900	COG3473	Maleate cis-trans isomerase
BH373_RS18910	COG2068	MobA-Related Protein
BH373_RS18935	COG2204	response regulator
BH373_RS18940	COG5000	phosphorelay sensor kinase activity
BH373_RS18950	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BH373_RS18950	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BH373_RS18960	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
BH373_RS18985	COG0583	DNA-binding transcription factor activity
BH373_RS19005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BH373_RS19010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BH373_RS19025	COG0758	DNA mediated transformation
BH373_RS19030	COG1522	sequence-specific DNA binding
BH373_RS19040	COG0242	peptide deformylase activity
BH373_RS19050	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BH373_RS19060	COG0546	phosphoglycolate phosphatase activity
BH373_RS19080	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BH373_RS19085	COG1942	4-Oxalocrotonate Tautomerase
BH373_RS19090	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BH373_RS19110	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BH373_RS19130	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BH373_RS19135	COG1024	Enoyl-CoA hydratase
BH373_RS19140	COG1414	Transcriptional regulator
BH373_RS19145	COG0318	PFAM AMP-dependent synthetase and ligase
BH373_RS19150	COG3181	Tripartite tricarboxylate transporter family receptor
BH373_RS19195	COG3422	double-strand break repair
BH373_RS19200	COG0330	HflC and HflK could
BH373_RS19210	COG0251	oxidation-reduction process
BH373_RS19255	COG3723	Recombinational DNA repair protein, rece pathway
BH373_RS19290	COG0582	viral genome integration into host DNA
BH373_RS19325	COG0706	membrane insertase activity
BH373_RS19330	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BH373_RS19335	COG0594	ribonuclease P activity
BH373_RS19340	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BH373_RS19345	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BH373_RS19360	COG1414	Transcriptional regulator
BH373_RS19365	COG0154	amidase activity
BH373_RS19380	COG1304	FMN binding
BH373_RS19430	COG0183	Belongs to the thiolase family
BH373_RS19435	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BH373_RS19450	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BH373_RS19455	COG3181	Tripartite tricarboxylate transporter family receptor
BH373_RS19465	COG2358	TRAP transporter, solute receptor (TAXI family
BH373_RS19475	COG1629	transport
BH373_RS19480	COG2922	Belongs to the Smg family
BH373_RS19505	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BH373_RS19510	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BH373_RS19515	COG1028	Short-chain dehydrogenase reductase Sdr
BH373_RS19520	COG1012	belongs to the aldehyde dehydrogenase family
BH373_RS19530	COG0028	Belongs to the TPP enzyme family
BH373_RS19535	COG1522	sequence-specific DNA binding
BH373_RS19540	COG3781	membrane
BH373_RS19550	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BH373_RS19570	COG4206	TonB-dependent receptor
BH373_RS19575	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BH373_RS19580	COG2022	thiamine diphosphate biosynthetic process
BH373_RS19585	COG0351	phosphomethylpyrimidine kinase
BH373_RS19590	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BH373_RS19605	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BH373_RS19615	COG0628	permease
BH373_RS19625	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BH373_RS19640	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BH373_RS19645	COG0049	tRNA binding
BH373_RS19650	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BH373_RS19655	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BH373_RS19660	COG0051	transcription antitermination factor activity, RNA binding
BH373_RS19665	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BH373_RS19670	COG0088	Forms part of the polypeptide exit tunnel
BH373_RS19675	COG0089	rRNA binding
BH373_RS19680	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BH373_RS19685	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BH373_RS19690	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BH373_RS19695	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BH373_RS19700	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BH373_RS19705	COG0255	Belongs to the universal ribosomal protein uL29 family
BH373_RS19710	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BH373_RS19730	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BH373_RS19735	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BH373_RS19740	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BH373_RS19745	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BH373_RS19750	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BH373_RS19755	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BH373_RS19760	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BH373_RS19765	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BH373_RS19770	COG1841	ribosomal large subunit assembly
BH373_RS19775	COG0200	Binds to the 23S rRNA
BH373_RS19780	COG0201	protein transport
BH373_RS19785	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BH373_RS19790	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BH373_RS19795	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BH373_RS19800	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BH373_RS19805	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BH373_RS19810	COG0202	RNA polymerase activity
BH373_RS19815	COG0203	ribosomal protein L17
BH373_RS19825	COG1324	tolerance protein
BH373_RS19830	COG4232	protein-disulfide reductase activity
BH373_RS19845	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BH373_RS19855	COG1333	cytochrome c biogenesis protein
BH373_RS19860	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BH373_RS19870	COG1965	Belongs to the frataxin family
BH373_RS19880	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BH373_RS19885	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BH373_RS19890	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BH373_RS19905	COG2814	Major facilitator Superfamily
BH373_RS19910	COG0629	single-stranded DNA binding
BH373_RS19950	COG0402	S-adenosylhomocysteine deaminase activity
BH373_RS19960	COG0438	transferase activity, transferring glycosyl groups
BH373_RS19980	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BH373_RS20005	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BH373_RS20030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BH373_RS20035	COG1956	GAF domain-containing protein
BH373_RS20040	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BH373_RS20050	COG1652	LysM domain
BH373_RS20065	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BH373_RS20080	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BH373_RS20105	COG3181	Tripartite tricarboxylate transporter family receptor
BH373_RS20120	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BH373_RS20135	COG1024	Enoyl-CoA hydratase
BH373_RS20150	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH373_RS20155	COG1309	transcriptional regulator
BH373_RS20160	COG2816	NAD+ diphosphatase activity
BH373_RS20165	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BH373_RS20250	COG2814	Major facilitator Superfamily
BH373_RS20255	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BH373_RS20275	COG1999	signal sequence binding
BH373_RS20280	COG0109	protoheme IX farnesyltransferase activity
BH373_RS20320	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BH373_RS20340	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BH373_RS20345	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BH373_RS20355	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BH373_RS20360	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
BH373_RS20370	COG0067	glutamate synthase
BH373_RS20370	COG0069	glutamate synthase activity
BH373_RS20370	COG0070	glutamate synthase
BH373_RS20380	COG3047	cAMP biosynthetic process
BH373_RS20390	COG1127	ABC transporter
BH373_RS20395	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BH373_RS20400	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BH373_RS20405	COG2853	Lipoprotein
BH373_RS20420	COG0842	Transport permease protein
BH373_RS20430	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BH373_RS20435	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BH373_RS20440	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BH373_RS20445	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BH373_RS20450	COG0131	Imidazoleglycerol-phosphate dehydratase
BH373_RS20455	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BH373_RS20460	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BH373_RS20465	COG0107	imidazoleglycerol-phosphate synthase activity
BH373_RS20470	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BH373_RS20475	COG0140	phosphoribosyl-ATP diphosphatase activity
BH373_RS20480	COG0537	adenosine 5'-monophosphoramidase activity
BH373_RS20485	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BH373_RS20490	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BH373_RS20505	COG3181	Tripartite tricarboxylate transporter family receptor
BH373_RS20540	COG3702	type iv secretory pathway
BH373_RS20545	COG3451	type IV secretory pathway VirB4
BH373_RS20560	COG3736	Type IV secretory pathway, component VirB8
BH373_RS20565	COG3504	Conjugal transfer protein
BH373_RS20570	COG2948	multi-organism process
BH373_RS20575	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
BH373_RS20585	COG0697	spore germination
BH373_RS20605	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BH373_RS20610	COG0747	negative chemotaxis
BH373_RS20620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BH373_RS20635	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BH373_RS20645	COG0494	nUDIX hydrolase
BH373_RS20685	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
BH373_RS20690	COG0237	dephospho-CoA kinase activity
BH373_RS20695	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BH373_RS20710	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BH373_RS20715	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BH373_RS20725	COG0477	Major facilitator Superfamily
BH373_RS20730	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BH373_RS20745	COG1126	abc transporter atp-binding protein
BH373_RS20750	COG0765	amino acid transport
BH373_RS20755	COG4597	amino acid ABC transporter
BH373_RS20760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BH373_RS20765	COG2884	Cell division ATP-binding protein ftsE
BH373_RS20770	COG2177	Part of the ABC transporter FtsEX involved in
BH373_RS20775	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BH373_RS20785	COG1194	a g-specific adenine glycosylase
BH373_RS20795	COG2226	methyltransferase
BH373_RS20805	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH373_RS20810	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH373_RS20825	COG1024	Enoyl-CoA hydratase
BH373_RS20845	COG1024	Enoyl-CoA hydratase
BH373_RS20850	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH373_RS20865	COG0753	catalase activity
BH373_RS20870	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BH373_RS20875	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BH373_RS20885	COG2175	clavaminate synthase activity
BH373_RS20890	COG1473	amidohydrolase
BH373_RS20895	COG4608	Belongs to the ABC transporter superfamily
BH373_RS20900	COG0444	Belongs to the ABC transporter superfamily
BH373_RS20915	COG0747	negative chemotaxis
BH373_RS20920	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BH373_RS20935	COG5002	protein histidine kinase activity
BH373_RS20935	COG3850	Histidine kinase
BH373_RS20955	COG0436	Aminotransferase
BH373_RS20960	COG1278	Cold shock
BH373_RS21115	COG1596	polysaccharide export
BH373_RS21115	COG1555	photosystem II stabilization
BH373_RS21230	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BH373_RS21300	COG0463	Glycosyl transferase, family 2
BH373_RS21380	COG3842	ATPase activity
BH373_RS21495	COG4172	Belongs to the ABC transporter superfamily
BH373_RS21545	COG0537	adenosine 5'-monophosphoramidase activity
BH373_RS21680	COG2333	competence protein COMEC
BH373_RS21680	COG0658	competence protein