locus-tag	class	description
BH372_RS00005	COG0445	tRNA wobble uridine modification
BH372_RS00010	COG0357	Ribosomal RNA small subunit methyltransferase G
BH372_RS00015	COG1192	Involved in chromosome partitioning
BH372_RS00025	COG1475	DNA binding
BH372_RS00030	COG0252	asparaginase activity
BH372_RS00055	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BH372_RS00065	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BH372_RS00075	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BH372_RS00080	COG0081	regulation of translation
BH372_RS00085	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BH372_RS00090	COG0222	ribosome binding
BH372_RS00095	COG0085	RNA polymerase activity
BH372_RS00100	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BH372_RS00140	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH372_RS00165	COG1024	Enoyl-CoA hydratase
BH372_RS00190	COG0752	glycyl-tRNA synthetase alpha subunit
BH372_RS00195	COG0751	glycine-tRNA ligase activity
BH372_RS00200	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BH372_RS00205	COG0204	Acyl-transferase
BH372_RS00220	COG0242	peptide deformylase activity
BH372_RS00260	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BH372_RS00265	COG2813	Specifically methylates the guanine in position
BH372_RS00265	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BH372_RS00275	COG2223	nitrite transmembrane transporter activity
BH372_RS00285	COG1794	racemase activity, acting on amino acids and derivatives
BH372_RS00290	COG1126	abc transporter atp-binding protein
BH372_RS00295	COG0765	amino acid transport
BH372_RS00300	COG0765	amino acid transport
BH372_RS00305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BH372_RS00365	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BH372_RS00395	COG0326	Molecular chaperone. Has ATPase activity
BH372_RS00400	COG0625	glutathione transferase activity
BH372_RS00415	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BH372_RS00420	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BH372_RS00450	COG0438	transferase activity, transferring glycosyl groups
BH372_RS00455	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BH372_RS00460	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BH372_RS00490	COG0859	PFAM glycosyl transferase family 9
BH372_RS00505	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BH372_RS00515	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BH372_RS00520	COG1127	ABC transporter
BH372_RS00545	COG1686	Belongs to the peptidase S11 family
BH372_RS00555	COG2921	Belongs to the UPF0250 family
BH372_RS00560	COG0321	lipoyl(octanoyl) transferase activity
BH372_RS00565	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BH372_RS00600	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BH372_RS00610	COG0018	arginyl-trna synthetase
BH372_RS00630	COG0395	ABC-type sugar transport system, permease component
BH372_RS00635	COG1175	transmembrane transport
BH372_RS00640	COG1653	transport
BH372_RS00645	COG3842	ATPase activity
BH372_RS00650	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BH372_RS00660	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BH372_RS00680	COG1609	Transcriptional regulator
BH372_RS00690	COG0154	amidase activity
BH372_RS00695	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BH372_RS00705	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BH372_RS00715	COG0583	DNA-binding transcription factor activity
BH372_RS00735	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BH372_RS00750	COG1802	Transcriptional regulator
BH372_RS00765	COG1024	Enoyl-CoA hydratase
BH372_RS00780	COG3181	Tripartite tricarboxylate transporter family receptor
BH372_RS00795	COG1984	allophanate hydrolase subunit 2
BH372_RS00800	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BH372_RS00810	COG0583	DNA-binding transcription factor activity
BH372_RS00815	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BH372_RS00825	COG5002	protein histidine kinase activity
BH372_RS00835	COG5002	protein histidine kinase activity
BH372_RS00840	COG0745	RESPONSE REGULATOR receiver
BH372_RS00845	COG2226	methyltransferase
BH372_RS00860	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BH372_RS00880	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BH372_RS00890	COG0513	Belongs to the DEAD box helicase family
BH372_RS00895	COG1280	lysine exporter protein (LysE YggA)
BH372_RS00900	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BH372_RS00945	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BH372_RS00945	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BH372_RS00955	COG0489	protein tyrosine kinase activity
BH372_RS00970	COG0717	Belongs to the dCTP deaminase family
BH372_RS00995	COG1982	Orn Lys Arg decarboxylase major
BH372_RS01000	COG2081	HI0933 family
BH372_RS01010	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BH372_RS01020	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BH372_RS01025	COG0509	glycine decarboxylation via glycine cleavage system
BH372_RS01030	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BH372_RS01030	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BH372_RS01070	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BH372_RS01085	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BH372_RS01095	COG1414	Transcriptional regulator
BH372_RS01100	COG1028	Short-chain dehydrogenase reductase Sdr
BH372_RS01105	COG2031	fatty acid transporter
BH372_RS01110	COG1250	3-hydroxyacyl-CoA dehydrogenase
BH372_RS01120	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BH372_RS01125	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BH372_RS01135	COG4257	antibiotic catabolic process
BH372_RS01155	COG1012	belongs to the aldehyde dehydrogenase family
BH372_RS01160	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BH372_RS01165	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BH372_RS01190	COG1028	Short-chain dehydrogenase reductase Sdr
BH372_RS01200	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BH372_RS01210	COG2188	Transcriptional regulator
BH372_RS01215	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BH372_RS01240	COG0617	tRNA 3'-terminal CCA addition
BH372_RS01255	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BH372_RS01260	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BH372_RS01265	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BH372_RS01270	COG0586	Pfam SNARE associated Golgi protein
BH372_RS01275	COG0860	N-Acetylmuramoyl-L-alanine amidase
BH372_RS01280	COG0802	atpase or kinase
BH372_RS01285	COG0114	fumarate hydratase activity
BH372_RS01295	COG3181	Tripartite tricarboxylate transporter family receptor
BH372_RS01305	COG0405	Gamma-glutamyltransferase
BH372_RS01310	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH372_RS01345	COG1294	oxidase, subunit
BH372_RS01355	COG4988	ABC transporter
BH372_RS01360	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BH372_RS01365	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BH372_RS01405	COG2969	positive regulation of protein catabolic process
BH372_RS01410	COG0625	glutathione transferase activity
BH372_RS01415	COG2857	Cytochrome c1
BH372_RS01420	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BH372_RS01425	COG0723	plastoquinol--plastocyanin reductase activity
BH372_RS01430	COG1970	mechanosensitive ion channel activity
BH372_RS01435	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BH372_RS01450	COG2808	Putative FMN-binding domain
BH372_RS01455	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BH372_RS01460	COG0747	negative chemotaxis
BH372_RS01465	COG0657	acetylesterase activity
BH372_RS01475	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BH372_RS01480	COG2207	Transcriptional regulator
BH372_RS01485	COG0129	dihydroxy-acid dehydratase activity
BH372_RS01490	COG2814	Major facilitator Superfamily
BH372_RS01495	COG0583	DNA-binding transcription factor activity
BH372_RS01505	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
BH372_RS01575	COG1024	Enoyl-CoA hydratase
BH372_RS01580	COG1960	acyl-CoA dehydrogenase activity
BH372_RS01605	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BH372_RS01610	COG0352	thiamine-phosphate diphosphorylase activity
BH372_RS01625	COG1678	Uncharacterized ACR, COG1678
BH372_RS01630	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BH372_RS01635	COG0540	Belongs to the ATCase OTCase family
BH372_RS01650	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BH372_RS01660	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BH372_RS01695	COG1234	tRNA 3'-trailer cleavage
BH372_RS01710	COG3064	Membrane
BH372_RS01740	COG1683	Conserved Protein
BH372_RS01745	COG1120	ATPase activity
BH372_RS01750	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BH372_RS01755	COG4558	Periplasmic binding protein
BH372_RS01760	COG3720	iron ion transport
BH372_RS01770	COG3712	iron ion homeostasis
BH372_RS01775	COG1595	DNA-templated transcription, initiation
BH372_RS01810	COG1802	Transcriptional regulator
BH372_RS01820	COG3069	C4-dicarboxylate transmembrane transporter activity
BH372_RS01830	COG1012	belongs to the aldehyde dehydrogenase family
BH372_RS01865	COG2860	membrane
BH372_RS01870	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BH372_RS01875	COG0708	Exodeoxyribonuclease III
BH372_RS01880	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BH372_RS01885	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BH372_RS01890	COG0154	amidase activity
BH372_RS01895	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BH372_RS01900	COG1077	Cell shape determining protein MreB Mrl
BH372_RS01905	COG1792	Involved in formation and maintenance of cell shape
BH372_RS01915	COG0768	penicillin binding
BH372_RS01920	COG0772	Belongs to the SEDS family
BH372_RS01925	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BH372_RS01930	COG0471	metal ion transport
BH372_RS01935	COG1309	transcriptional regulator
BH372_RS01945	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BH372_RS01960	COG2823	Periplasmic or secreted lipoprotein
BH372_RS01965	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BH372_RS01980	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BH372_RS02000	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH372_RS02010	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH372_RS02035	COG0492	ferredoxin-NADP+ reductase activity
BH372_RS02050	COG3181	Tripartite tricarboxylate transporter family receptor
BH372_RS02055	COG1250	3-hydroxyacyl-CoA dehydrogenase
BH372_RS02055	COG1024	Enoyl-CoA hydratase
BH372_RS02060	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH372_RS02065	COG0028	Belongs to the TPP enzyme family
BH372_RS02090	COG3181	Tripartite tricarboxylate transporter family receptor
BH372_RS02100	COG0697	spore germination
BH372_RS02125	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BH372_RS02130	COG0463	Glycosyl transferase, family 2
BH372_RS02145	COG0786	glutamate:sodium symporter activity
BH372_RS02155	COG2031	fatty acid transporter
BH372_RS02170	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BH372_RS02185	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BH372_RS02200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BH372_RS02210	COG1285	pathogenesis
BH372_RS02215	COG1253	flavin adenine dinucleotide binding
BH372_RS02220	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH372_RS02225	COG1024	Enoyl-CoA hydratase
BH372_RS02230	COG3181	Tripartite tricarboxylate transporter family receptor
BH372_RS02235	COG0583	DNA-binding transcription factor activity
BH372_RS02240	COG1960	acyl-CoA dehydrogenase activity
BH372_RS02250	COG0183	Belongs to the thiolase family
BH372_RS02270	COG0583	DNA-binding transcription factor activity
BH372_RS02275	COG1278	Cold shock
BH372_RS02285	COG1802	Transcriptional regulator
BH372_RS02290	COG1012	belongs to the aldehyde dehydrogenase family
BH372_RS02295	COG2031	fatty acid transporter
BH372_RS02300	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BH372_RS02300	COG1017	nitric oxide dioxygenase activity
BH372_RS02305	COG0251	oxidation-reduction process
BH372_RS02330	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH372_RS02340	COG0583	DNA-binding transcription factor activity
BH372_RS02345	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH372_RS02355	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
BH372_RS02360	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BH372_RS02365	COG0546	phosphoglycolate phosphatase activity
BH372_RS02375	COG1530	ribonuclease E activity
BH372_RS02395	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BH372_RS02400	COG0159	tryptophan synthase activity
BH372_RS02405	COG0133	tryptophan synthase activity
BH372_RS02415	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BH372_RS02420	COG3228	Belongs to the MtfA family
BH372_RS02430	COG0251	oxidation-reduction process
BH372_RS02435	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BH372_RS02440	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BH372_RS02455	COG2878	Part of a membrane complex involved in electron transport
BH372_RS02460	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BH372_RS02495	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BH372_RS02515	COG1268	BioY protein
BH372_RS02520	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BH372_RS02525	COG1122	ATPase activity
BH372_RS02530	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BH372_RS02545	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BH372_RS02550	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BH372_RS02560	COG1196	nuclear chromosome segregation
BH372_RS02565	COG0477	Major facilitator Superfamily
BH372_RS02570	COG1573	uracil-dna glycosylase
BH372_RS02575	COG1214	PFAM Peptidase M22, glycoprotease
BH372_RS02580	COG0745	RESPONSE REGULATOR receiver
BH372_RS02595	COG0450	alkyl hydroperoxide reductase
BH372_RS02600	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BH372_RS02610	COG2223	nitrite transmembrane transporter activity
BH372_RS02625	COG2186	Transcriptional regulator
BH372_RS02645	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BH372_RS02655	COG0583	DNA-binding transcription factor activity
BH372_RS02665	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BH372_RS02670	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BH372_RS02675	COG0137	argininosuccinate synthase activity
BH372_RS02680	COG3158	transport of potassium into the cell
BH372_RS02685	COG0642	Histidine kinase
BH372_RS02715	COG0776	regulation of translation
BH372_RS02720	COG3128	pkhd-type hydroxylase
BH372_RS02730	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BH372_RS02735	COG0557	exoribonuclease II activity
BH372_RS02760	COG0679	Auxin Efflux Carrier
BH372_RS02765	COG2391	methyltransferase activity
BH372_RS02770	COG0069	glutamate synthase activity
BH372_RS02780	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BH372_RS02790	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
BH372_RS02830	COG3706	GGDEF domain
BH372_RS02850	COG0583	DNA-binding transcription factor activity
BH372_RS02860	COG1053	succinate dehydrogenase
BH372_RS02880	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BH372_RS02885	COG0459	protein refolding
BH372_RS02890	COG3468	outer membrane autotransporter barrel domain protein
BH372_RS02905	COG1252	NADH dehydrogenase
BH372_RS02910	COG0284	orotidine-5'-phosphate decarboxylase activity
BH372_RS02915	COG1058	Belongs to the CinA family
BH372_RS02915	COG1546	Belongs to the CinA family
BH372_RS02920	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BH372_RS02930	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BH372_RS02935	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BH372_RS02975	COG3639	organic phosphonate transmembrane transporter activity
BH372_RS02980	COG3639	organic phosphonate transmembrane transporter activity
BH372_RS03000	COG0742	ribosomal rna small subunit methyltransferase
BH372_RS03005	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BH372_RS03010	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BH372_RS03015	COG3135	benzoate transporter
BH372_RS03030	COG0640	Transcriptional regulator
BH372_RS03060	COG4172	Belongs to the ABC transporter superfamily
BH372_RS03065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BH372_RS03070	COG0601	transmembrane transport
BH372_RS03080	COG0281	malic enzyme
BH372_RS03080	COG0280	phosphate acetyltransferase
BH372_RS03140	COG0583	DNA-binding transcription factor activity
BH372_RS03150	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BH372_RS03155	COG0167	dihydroorotate dehydrogenase activity
BH372_RS03175	COG1414	Transcriptional regulator
BH372_RS03180	COG1546	Belongs to the CinA family
BH372_RS03180	COG1058	Belongs to the CinA family
BH372_RS03200	COG0513	Belongs to the DEAD box helicase family
BH372_RS03230	COG0429	hydrolase of the alpha beta-hydrolase fold
BH372_RS03235	COG4783	chaperone-mediated protein folding
BH372_RS03250	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BH372_RS03275	COG0006	proline dipeptidase activity
BH372_RS03285	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BH372_RS03305	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BH372_RS03310	COG0632	four-way junction helicase activity
BH372_RS03325	COG2255	four-way junction helicase activity
BH372_RS03330	COG0514	ATP-dependent DNA helicase (RecQ)
BH372_RS03345	COG0288	reversible hydration of carbon dioxide
BH372_RS03350	COG0154	amidase activity
BH372_RS03360	COG4211	Belongs to the binding-protein-dependent transport system permease family
BH372_RS03390	COG1464	Belongs to the NlpA lipoprotein family
BH372_RS03535	COG1196	nuclear chromosome segregation
BH372_RS03600	COG2135	peptidase activity
BH372_RS03615	COG0494	nUDIX hydrolase
BH372_RS03620	COG0442	prolyl-tRNA aminoacylation
BH372_RS03625	COG0824	Thioesterase
BH372_RS03630	COG0811	peptide transport
BH372_RS03635	COG0848	biopolymer transport protein
BH372_RS03645	COG0823	Involved in the tonB-independent uptake of proteins
BH372_RS03660	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BH372_RS03665	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BH372_RS03695	COG0700	Nucleoside recognition
BH372_RS03700	COG0469	pyruvate kinase activity
BH372_RS03705	COG1929	Belongs to the glycerate kinase type-1 family
BH372_RS03710	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BH372_RS03715	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BH372_RS03720	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BH372_RS03730	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BH372_RS03740	COG2154	pterin-4-alpha-carbinolamine dehydratase
BH372_RS03765	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BH372_RS03770	COG0154	amidase activity
BH372_RS03780	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BH372_RS03785	COG0601	transmembrane transport
BH372_RS03790	COG0747	negative chemotaxis
BH372_RS03810	COG0019	diaminopimelate decarboxylase activity
BH372_RS03830	COG2353	YceI-like domain
BH372_RS03835	COG4774	siderophore transport
BH372_RS03840	COG3712	iron ion homeostasis
BH372_RS03880	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BH372_RS03885	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BH372_RS03890	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BH372_RS03895	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BH372_RS03905	COG0142	geranyltranstransferase activity
BH372_RS03915	COG0583	DNA-binding transcription factor activity
BH372_RS03925	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
BH372_RS03930	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BH372_RS03945	COG2994	toxin metabolic process
BH372_RS03955	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
BH372_RS03960	COG2274	protein secretion by the type I secretion system
BH372_RS03965	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BH372_RS03970	COG1538	Outer membrane efflux protein
BH372_RS03990	COG0765	amino acid transport
BH372_RS03995	COG1126	abc transporter atp-binding protein
BH372_RS04015	COG1028	Short-chain dehydrogenase reductase Sdr
BH372_RS04025	COG1802	Transcriptional regulator
BH372_RS04035	COG1802	Transcriptional regulator
BH372_RS04045	COG0318	PFAM AMP-dependent synthetase and ligase
BH372_RS04055	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BH372_RS04075	COG0028	Belongs to the TPP enzyme family
BH372_RS04105	COG0308	aminopeptidase N
BH372_RS04110	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BH372_RS04120	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BH372_RS04125	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BH372_RS04130	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BH372_RS04135	COG0560	Phosphoserine phosphatase
BH372_RS04140	COG0583	DNA-binding transcription factor activity
BH372_RS04145	COG3181	Tripartite tricarboxylate transporter family receptor
BH372_RS04150	COG0028	Belongs to the TPP enzyme family
BH372_RS04165	COG4774	siderophore transport
BH372_RS04170	COG4774	siderophore transport
BH372_RS04180	COG1007	ATP synthesis coupled electron transport
BH372_RS04195	COG0713	ATP synthesis coupled electron transport
BH372_RS04205	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BH372_RS04210	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BH372_RS04215	COG1034	ATP synthesis coupled electron transport
BH372_RS04225	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BH372_RS04230	COG0649	NAD binding
BH372_RS04235	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BH372_RS04240	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BH372_RS04245	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BH372_RS04250	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BH372_RS04275	COG0671	phosphoesterase, PA-phosphatase related
BH372_RS04285	COG1597	lipid kinase activity
BH372_RS04290	COG0583	DNA-binding transcription factor activity
BH372_RS04295	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BH372_RS04305	COG1733	regulation of RNA biosynthetic process
BH372_RS04310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BH372_RS04315	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BH372_RS04330	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
BH372_RS04350	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BH372_RS04370	COG3608	succinylglutamate desuccinylase aspartoacylase
BH372_RS04375	COG0626	cystathionine gamma-synthase activity
BH372_RS04380	COG0583	DNA-binding transcription factor activity
BH372_RS04420	COG3799	methylaspartate ammonia-lyase activity
BH372_RS04430	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BH372_RS04440	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BH372_RS04445	COG0149	triose-phosphate isomerase activity
BH372_RS04465	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BH372_RS04480	COG1185	polyribonucleotide nucleotidyltransferase activity
BH372_RS04485	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BH372_RS04495	COG1183	phosphatidylcholine synthase activity
BH372_RS04500	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BH372_RS04505	COG0440	acetolactate synthase activity
BH372_RS04510	COG0028	Belongs to the TPP enzyme family
BH372_RS04525	COG5265	(ABC) transporter
BH372_RS04530	COG0500	methyltransferase
BH372_RS04545	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
BH372_RS04575	COG0511	ligase activity, forming carbon-carbon bonds
BH372_RS04600	COG2188	Transcriptional regulator
BH372_RS04605	COG0439	Biotin carboxylase
BH372_RS04655	COG5265	(ABC) transporter
BH372_RS04665	COG0667	Aldo Keto reductase
BH372_RS04680	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BH372_RS04715	COG0583	DNA-binding transcription factor activity
BH372_RS04740	COG2814	Major facilitator Superfamily
BH372_RS04750	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BH372_RS04765	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BH372_RS04775	COG0287	Prephenate dehydrogenase
BH372_RS04780	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BH372_RS04785	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BH372_RS04805	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BH372_RS04810	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BH372_RS04815	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BH372_RS04835	COG2951	lytic endotransglycosylase activity
BH372_RS04840	COG0123	including yeast histone deacetylase and acetoin utilization protein
BH372_RS04855	COG1960	acyl-CoA dehydrogenase activity
BH372_RS04860	COG0450	alkyl hydroperoxide reductase
BH372_RS04885	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BH372_RS04920	COG0335	large ribosomal subunit rRNA binding
BH372_RS04935	COG0667	Aldo Keto reductase
BH372_RS04950	COG3161	chorismate lyase activity
BH372_RS04955	COG1187	pseudouridine synthase activity
BH372_RS04985	COG1999	signal sequence binding
BH372_RS04990	COG0339	signal peptide processing
BH372_RS04995	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BH372_RS05000	COG4566	intracellular signal transduction
BH372_RS05010	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BH372_RS05015	COG0508	dehydrogenase complex catalyzes the overall conversion of
BH372_RS05020	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BH372_RS05025	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BH372_RS05035	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BH372_RS05040	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BH372_RS05045	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BH372_RS05050	COG0126	phosphoglycerate kinase activity
BH372_RS05055	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BH372_RS05060	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BH372_RS05075	COG0625	glutathione transferase activity
BH372_RS05105	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BH372_RS05115	COG0521	Mo-molybdopterin cofactor biosynthetic process
BH372_RS05125	COG0739	heme binding
BH372_RS05135	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BH372_RS05170	COG0745	RESPONSE REGULATOR receiver
BH372_RS05185	COG0840	transmembrane signaling receptor activity
BH372_RS05195	COG2201	protein-glutamate methylesterase activity
BH372_RS05200	COG0745	RESPONSE REGULATOR receiver
BH372_RS05205	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
BH372_RS05230	COG0667	Aldo Keto reductase
BH372_RS05240	COG4535	Mg2 and Co2 transporter CorC
BH372_RS05245	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BH372_RS05250	COG1702	phosphate starvation-inducible protein PhoH
BH372_RS05255	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BH372_RS05270	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BH372_RS05275	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BH372_RS05280	COG1862	Preprotein translocase
BH372_RS05285	COG0343	queuine tRNA-ribosyltransferase activity
BH372_RS05290	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BH372_RS05295	COG2027	D-alanyl-D-alanine carboxypeptidase
BH372_RS05300	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BH372_RS05310	COG3468	outer membrane autotransporter barrel domain protein
BH372_RS05315	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BH372_RS05315	COG1648	precorrin-2 dehydrogenase activity
BH372_RS05340	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BH372_RS05345	COG0741	lytic transglycosylase activity
BH372_RS05350	COG0436	Aminotransferase
BH372_RS05360	COG0280	phosphate acetyltransferase
BH372_RS05360	COG0281	malic enzyme
BH372_RS05370	COG2732	(Barnase) inhibitor
BH372_RS05385	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BH372_RS05410	COG0248	Ppx GppA phosphatase
BH372_RS05420	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BH372_RS05430	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BH372_RS05435	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BH372_RS05440	COG1534	Rna-binding protein
BH372_RS05465	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BH372_RS05480	COG1295	ribonuclease BN
BH372_RS05490	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BH372_RS05495	COG0745	RESPONSE REGULATOR receiver
BH372_RS05500	COG2205	protein histidine kinase activity
BH372_RS05535	COG1022	Amp-dependent synthetase and ligase
BH372_RS05550	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BH372_RS05555	COG1028	Short-chain dehydrogenase reductase Sdr
BH372_RS05565	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BH372_RS05580	COG1136	(ABC) transporter
BH372_RS05585	COG0084	hydrolase, TatD family'
BH372_RS05620	COG0613	PHP domain protein
BH372_RS05635	COG3539	Fimbrial protein
BH372_RS05640	COG0281	malic enzyme
BH372_RS05640	COG0280	phosphate acetyltransferase
BH372_RS05650	COG1522	sequence-specific DNA binding
BH372_RS05665	COG0567	Dehydrogenase, E1 component
BH372_RS05670	COG0508	dehydrogenase complex catalyzes the overall conversion of
BH372_RS05675	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BH372_RS05680	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BH372_RS05685	COG1028	Short-chain dehydrogenase reductase Sdr
BH372_RS05690	COG0583	DNA-binding transcription factor activity
BH372_RS05700	COG3181	Tripartite tricarboxylate transporter family receptor
BH372_RS05720	COG0180	Tryptophanyl-tRNA synthetase
BH372_RS05725	COG2183	response to ionizing radiation
BH372_RS05730	COG1199	ATP-dependent helicase activity
BH372_RS05740	COG0564	pseudouridine synthase activity
BH372_RS05750	COG3243	poly(R)-hydroxyalkanoic acid synthase
BH372_RS05755	COG1028	Short-chain dehydrogenase reductase Sdr
BH372_RS05760	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
BH372_RS05775	COG0672	)-iron permease
BH372_RS05820	COG0583	DNA-binding transcription factor activity
BH372_RS05830	COG2814	Major facilitator Superfamily
BH372_RS05845	COG1619	proteins homologs of microcin C7 resistance protein MccF
BH372_RS05860	COG2084	Dehydrogenase
BH372_RS05865	COG3181	Tripartite tricarboxylate transporter family receptor
BH372_RS05890	COG2988	succinylglutamate desuccinylase activity
BH372_RS05915	COG0765	amino acid transport
BH372_RS05920	COG0765	amino acid transport
BH372_RS05925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BH372_RS05960	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BH372_RS05965	COG1595	DNA-templated transcription, initiation
BH372_RS05975	COG3530	Putative quorum-sensing-regulated virulence factor
BH372_RS05980	COG0494	nUDIX hydrolase
BH372_RS05995	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BH372_RS06000	COG0542	response to heat
BH372_RS06025	COG5441	Belongs to the UPF0261 family
BH372_RS06030	COG5564	TIM-barrel signal transduction protein
BH372_RS06045	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BH372_RS06060	COG1477	protein flavinylation
BH372_RS06080	COG1131	(ABC) transporter
BH372_RS06085	COG0842	Transport permease protein
BH372_RS06095	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BH372_RS06100	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
BH372_RS06100	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
BH372_RS06105	COG1562	ergosterol biosynthetic process
BH372_RS06110	COG1562	ergosterol biosynthetic process
BH372_RS06115	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BH372_RS06120	COG1028	Short-chain dehydrogenase reductase Sdr
BH372_RS06140	COG2304	oxidoreductase activity
BH372_RS06160	COG0534	Mate efflux family protein
BH372_RS06170	COG0254	rRNA binding
BH372_RS06175	COG3483	tryptophan 2,3-dioxygenase activity
BH372_RS06180	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BH372_RS06185	COG2003	Belongs to the UPF0758 family
BH372_RS06190	COG1047	Peptidyl-prolyl cis-trans
BH372_RS06195	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BH372_RS06200	COG0625	glutathione transferase activity
BH372_RS06220	COG0523	cobalamin synthesis protein
BH372_RS06230	COG0583	DNA-binding transcription factor activity
BH372_RS06240	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BH372_RS06245	COG1187	pseudouridine synthase activity
BH372_RS06250	COG0779	Required for maturation of 30S ribosomal subunits
BH372_RS06255	COG0195	Participates in both transcription termination and antitermination
BH372_RS06255	COG2251	uridine kinase activity
BH372_RS06260	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BH372_RS06265	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BH372_RS06270	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BH372_RS06290	COG1611	Belongs to the LOG family
BH372_RS06305	COG0412	Dienelactone hydrolase
BH372_RS06310	COG1283	sodium-dependent phosphate transmembrane transporter activity
BH372_RS06315	COG1760	l-serine dehydratase
BH372_RS06320	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BH372_RS06325	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BH372_RS06335	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BH372_RS06360	COG2311	Membrane
BH372_RS06385	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BH372_RS06405	COG0559	Belongs to the binding-protein-dependent transport system permease family
BH372_RS06420	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BH372_RS06430	COG1653	transport
BH372_RS06435	COG1175	transmembrane transport
BH372_RS06440	COG0395	ABC-type sugar transport system, permease component
BH372_RS06445	COG3842	ATPase activity
BH372_RS06470	COG2363	Small membrane protein
BH372_RS06485	COG1464	Belongs to the NlpA lipoprotein family
BH372_RS06495	COG0688	phosphatidylethanolamine metabolic process
BH372_RS06525	COG0625	glutathione transferase activity
BH372_RS06530	COG0386	Belongs to the glutathione peroxidase family
BH372_RS06550	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH372_RS06580	COG2259	Doxx family
BH372_RS06595	COG0667	Aldo Keto reductase
BH372_RS06625	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BH372_RS06650	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BH372_RS06660	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BH372_RS06715	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BH372_RS06720	COG3568	Endonuclease Exonuclease Phosphatase
BH372_RS06725	COG1695	Transcriptional regulator
BH372_RS06745	COG0583	DNA-binding transcription factor activity
BH372_RS06760	COG1802	Transcriptional regulator
BH372_RS06770	COG3181	Tripartite tricarboxylate transporter family receptor
BH372_RS06780	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH372_RS06795	COG0066	3-isopropylmalate dehydratase activity
BH372_RS06805	COG3181	Tripartite tricarboxylate transporter family receptor
BH372_RS06810	COG4948	Mandelate Racemase Muconate Lactonizing
BH372_RS06825	COG1126	abc transporter atp-binding protein
BH372_RS06835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BH372_RS06875	COG1815	bacterial-type flagellum-dependent cell motility
BH372_RS06880	COG1558	bacterial-type flagellum-dependent cell motility
BH372_RS06890	COG1749	Flagellar hook protein flgE
BH372_RS06905	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BH372_RS06910	COG1706	bacterial-type flagellum-dependent cell motility
BH372_RS06920	COG1256	bacterial-type flagellum assembly
BH372_RS06930	COG0840	transmembrane signaling receptor activity
BH372_RS06935	COG0840	transmembrane signaling receptor activity
BH372_RS06940	COG0840	transmembrane signaling receptor activity
BH372_RS06960	COG1338	Plays a role in the flagellum-specific transport system
BH372_RS06980	COG1580	Controls the rotational direction of flagella during chemotaxis
BH372_RS07010	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BH372_RS07030	COG0559	Belongs to the binding-protein-dependent transport system permease family
BH372_RS07045	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BH372_RS07055	COG1653	transport
BH372_RS07060	COG1175	transmembrane transport
BH372_RS07065	COG0395	ABC-type sugar transport system, permease component
BH372_RS07070	COG3842	ATPase activity
BH372_RS07095	COG2363	Small membrane protein
BH372_RS07110	COG1464	Belongs to the NlpA lipoprotein family
BH372_RS07120	COG0688	phosphatidylethanolamine metabolic process
BH372_RS07150	COG0625	glutathione transferase activity
BH372_RS07155	COG0386	Belongs to the glutathione peroxidase family
BH372_RS07175	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH372_RS07205	COG2259	Doxx family
BH372_RS07220	COG0667	Aldo Keto reductase
BH372_RS07250	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BH372_RS07275	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BH372_RS07285	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BH372_RS07340	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BH372_RS07345	COG3568	Endonuclease Exonuclease Phosphatase
BH372_RS07350	COG1695	Transcriptional regulator
BH372_RS07370	COG0583	DNA-binding transcription factor activity
BH372_RS07385	COG1802	Transcriptional regulator
BH372_RS07395	COG3181	Tripartite tricarboxylate transporter family receptor
BH372_RS07405	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH372_RS07420	COG0066	3-isopropylmalate dehydratase activity
BH372_RS07430	COG3181	Tripartite tricarboxylate transporter family receptor
BH372_RS07435	COG4948	Mandelate Racemase Muconate Lactonizing
BH372_RS07450	COG1126	abc transporter atp-binding protein
BH372_RS07460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BH372_RS07500	COG1815	bacterial-type flagellum-dependent cell motility
BH372_RS07505	COG1558	bacterial-type flagellum-dependent cell motility
BH372_RS07515	COG1749	Flagellar hook protein flgE
BH372_RS07530	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BH372_RS07535	COG1706	bacterial-type flagellum-dependent cell motility
BH372_RS07545	COG1256	bacterial-type flagellum assembly
BH372_RS07555	COG0840	transmembrane signaling receptor activity
BH372_RS07560	COG0840	transmembrane signaling receptor activity
BH372_RS07565	COG0840	transmembrane signaling receptor activity
BH372_RS07585	COG1338	Plays a role in the flagellum-specific transport system
BH372_RS07605	COG1580	Controls the rotational direction of flagella during chemotaxis
BH372_RS07630	COG1157	protein secretion by the type III secretion system
BH372_RS07640	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BH372_RS07650	COG1677	Flagellar hook-basal body complex protein FliE
BH372_RS07660	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BH372_RS07695	COG0285	dihydrofolate synthase activity
BH372_RS07725	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BH372_RS07730	COG0024	Methionine aminopeptidase
BH372_RS07735	COG0052	Belongs to the universal ribosomal protein uS2 family
BH372_RS07740	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BH372_RS07745	COG0528	UMP kinase activity
BH372_RS07750	COG0233	cytoplasmic translational termination
BH372_RS07755	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BH372_RS07765	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BH372_RS07770	COG0750	zinc metalloprotease
BH372_RS07775	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BH372_RS07780	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
BH372_RS07785	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BH372_RS07790	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BH372_RS07800	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BH372_RS07805	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BH372_RS07810	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BH372_RS07815	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BH372_RS07825	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BH372_RS07825	COG0519	Catalyzes the synthesis of GMP from XMP
BH372_RS07840	COG0330	HflC and HflK could
BH372_RS07845	COG3706	GGDEF domain
BH372_RS07850	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BH372_RS07860	COG2867	negative regulation of translational initiation
BH372_RS07870	COG1960	acyl-CoA dehydrogenase activity
BH372_RS07875	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BH372_RS07905	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BH372_RS07910	COG0505	Belongs to the CarA family
BH372_RS07915	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BH372_RS07925	COG0406	alpha-ribazole phosphatase activity
BH372_RS07935	COG3842	ATPase activity
BH372_RS07955	COG5001	Diguanylate cyclase
BH372_RS07960	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BH372_RS07970	COG1763	Mo-molybdopterin cofactor biosynthetic process
BH372_RS07975	COG0303	'Molybdopterin
BH372_RS07980	COG0746	molybdenum cofactor guanylyltransferase activity
BH372_RS07985	COG0489	protein tyrosine kinase activity
BH372_RS08015	COG3383	formate dehydrogenase (NAD+) activity
BH372_RS08015	COG0243	molybdopterin cofactor binding
BH372_RS08050	COG1122	ATPase activity
BH372_RS08060	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BH372_RS08065	COG0066	3-isopropylmalate dehydratase activity
BH372_RS08070	COG0473	3-isopropylmalate dehydrogenase activity
BH372_RS08075	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BH372_RS08085	COG0101	tRNA pseudouridine synthase activity
BH372_RS08090	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BH372_RS08105	COG0135	phosphoribosylanthranilate isomerase activity
BH372_RS08120	COG3022	response to hydroperoxide
BH372_RS08135	COG3023	N-Acetylmuramoyl-L-alanine amidase
BH372_RS08145	COG0424	maF-like protein
BH372_RS08150	COG1399	metal-binding, possibly nucleic acid-binding protein
BH372_RS08155	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BH372_RS08160	COG0416	fatty acid biosynthetic process
BH372_RS08165	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BH372_RS08180	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BH372_RS08185	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BH372_RS08210	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BH372_RS08215	COG0481	GTPase activity
BH372_RS08220	COG0681	Belongs to the peptidase S26 family
BH372_RS08225	COG0571	ribonuclease III activity
BH372_RS08230	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BH372_RS08235	COG1381	Involved in DNA repair and RecF pathway recombination
BH372_RS08260	COG3181	Tripartite tricarboxylate transporter family receptor
BH372_RS08265	COG0670	Belongs to the BI1 family
BH372_RS08280	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BH372_RS08290	COG0583	DNA-binding transcription factor activity
BH372_RS08305	COG0583	DNA-binding transcription factor activity
BH372_RS08320	COG0791	NLP P60 protein
BH372_RS08330	COG3193	protein, possibly involved in utilization of glycolate and propanediol
BH372_RS08340	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BH372_RS08345	COG0697	spore germination
BH372_RS08350	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
BH372_RS08365	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BH372_RS08395	COG1446	asparaginase
BH372_RS08400	COG4172	Belongs to the ABC transporter superfamily
BH372_RS08405	COG0747	negative chemotaxis
BH372_RS08415	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BH372_RS08440	COG0504	CTP synthase activity
BH372_RS08445	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BH372_RS08455	COG0148	phosphopyruvate hydratase activity
BH372_RS08460	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BH372_RS08490	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BH372_RS08500	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BH372_RS08555	COG0039	L-malate dehydrogenase activity
BH372_RS08560	COG2188	Transcriptional regulator
BH372_RS08565	COG2009	succinate dehydrogenase
BH372_RS08570	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BH372_RS08575	COG1053	succinate dehydrogenase
BH372_RS08580	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BH372_RS08585	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BH372_RS08590	COG0372	Belongs to the citrate synthase family
BH372_RS08620	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BH372_RS08625	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BH372_RS08640	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BH372_RS08645	COG3842	ATPase activity
BH372_RS08650	COG1176	ABC-type spermidine putrescine transport system, permease component I
BH372_RS08655	COG1177	transmembrane transport
BH372_RS08680	COG1960	acyl-CoA dehydrogenase activity
BH372_RS08685	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BH372_RS08690	COG0704	Plays a role in the regulation of phosphate uptake
BH372_RS08700	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
BH372_RS08705	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BH372_RS08705	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BH372_RS08710	COG1643	Atp-dependent helicase
BH372_RS08725	COG0438	transferase activity, transferring glycosyl groups
BH372_RS08730	COG0726	polysaccharide deacetylase
BH372_RS08735	COG0463	Glycosyl transferase, family 2
BH372_RS08740	COG0438	transferase activity, transferring glycosyl groups
BH372_RS08745	COG2194	sulfuric ester hydrolase activity
BH372_RS08770	COG0859	PFAM glycosyl transferase family 9
BH372_RS08775	COG1132	(ABC) transporter
BH372_RS08790	COG0077	Prephenate dehydratase
BH372_RS08795	COG1530	ribonuclease E activity
BH372_RS08835	COG3468	outer membrane autotransporter barrel domain protein
BH372_RS08840	COG0424	maF-like protein
BH372_RS08845	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BH372_RS08850	COG0799	negative regulation of ribosome biogenesis
BH372_RS08855	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BH372_RS08860	COG0408	coproporphyrinogen oxidase activity
BH372_RS08865	COG0151	Belongs to the GarS family
BH372_RS08870	COG0217	transcriptional regulatory protein
BH372_RS08875	COG0433	COG0433 Predicted ATPase
BH372_RS08880	COG1115	amino acid carrier protein
BH372_RS08885	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BH372_RS08895	COG1012	belongs to the aldehyde dehydrogenase family
BH372_RS08920	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BH372_RS08935	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BH372_RS08945	COG0747	negative chemotaxis
BH372_RS08955	COG0473	3-isopropylmalate dehydrogenase activity
BH372_RS08960	COG2814	Major facilitator Superfamily
BH372_RS08965	COG1566	PFAM secretion protein HlyD family protein
BH372_RS08975	COG1846	Transcriptional regulator
BH372_RS08985	COG0697	spore germination
BH372_RS08995	COG0501	Belongs to the peptidase M48B family
BH372_RS09015	COG0583	DNA-binding transcription factor activity
BH372_RS09020	COG3842	ATPase activity
BH372_RS09025	COG1178	ABC-type Fe3 transport system permease component
BH372_RS09030	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BH372_RS09035	COG1840	ABC-type Fe3 transport system, periplasmic component
BH372_RS09060	COG2233	PERMEase
BH372_RS09065	COG0840	transmembrane signaling receptor activity
BH372_RS09070	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BH372_RS09100	COG4789	Type iii secretion
BH372_RS09165	COG4669	(LipO)protein
BH372_RS09200	COG4790	Type iii secretion
BH372_RS09205	COG4794	Type iii secretion
BH372_RS09210	COG4791	protein targeting
BH372_RS09215	COG4792	protein secretion
BH372_RS09230	COG1595	DNA-templated transcription, initiation
BH372_RS09250	COG2208	phosphoserine phosphatase activity
BH372_RS09250	COG2770	Histidine kinase
BH372_RS09260	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BH372_RS09265	COG2172	sigma factor antagonist activity
BH372_RS09270	COG1366	Belongs to the anti-sigma-factor antagonist family
BH372_RS09275	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BH372_RS09305	COG2358	TRAP transporter, solute receptor (TAXI family
BH372_RS09310	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BH372_RS09340	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BH372_RS09340	COG1017	nitric oxide dioxygenase activity
BH372_RS09345	COG1959	2 iron, 2 sulfur cluster binding
BH372_RS09350	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BH372_RS09370	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BH372_RS09375	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BH372_RS09380	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BH372_RS09385	COG0084	hydrolase, TatD family'
BH372_RS09400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BH372_RS09410	COG1126	abc transporter atp-binding protein
BH372_RS09420	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BH372_RS09435	COG0028	Belongs to the TPP enzyme family
BH372_RS09455	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BH372_RS09495	COG4336	lyase activity
BH372_RS09505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BH372_RS09505	COG2205	protein histidine kinase activity
BH372_RS09510	COG2197	response regulator
BH372_RS09525	COG3121	Chaperone
BH372_RS09530	COG3188	usher protein
BH372_RS09535	COG3539	Fimbrial protein
BH372_RS09540	COG2831	hemolysin activation secretion protein
BH372_RS09555	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BH372_RS09605	COG0668	transmembrane transport
BH372_RS09630	COG1253	flavin adenine dinucleotide binding
BH372_RS09635	COG1968	undecaprenyl-diphosphatase activity
BH372_RS09640	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BH372_RS09655	COG0215	cysteine-tRNA ligase activity
BH372_RS09665	COG0825	malonyl-CoA metabolic process
BH372_RS09675	COG0037	tRNA processing
BH372_RS09680	COG0527	aspartate kinase activity
BH372_RS09705	COG1250	3-hydroxyacyl-CoA dehydrogenase
BH372_RS09710	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BH372_RS09725	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BH372_RS09730	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
BH372_RS09735	COG1028	Short-chain dehydrogenase reductase Sdr
BH372_RS09745	COG0583	DNA-binding transcription factor activity
BH372_RS09775	COG3842	ATPase activity
BH372_RS09785	COG0446	pyridine nucleotide-disulphide oxidoreductase
BH372_RS09785	COG1902	pentaerythritol trinitrate reductase activity
BH372_RS09790	COG1414	Transcriptional regulator
BH372_RS09795	COG1832	CoA-binding protein
BH372_RS09805	COG0251	oxidation-reduction process
BH372_RS09830	COG1902	pentaerythritol trinitrate reductase activity
BH372_RS09840	COG1215	transferase activity, transferring glycosyl groups
BH372_RS09845	COG0726	polysaccharide deacetylase
BH372_RS09845	COG1649	PFAM Uncharacterised BCR, COG1649
BH372_RS09865	COG1846	Transcriptional regulator
BH372_RS09900	COG2080	2 iron, 2 sulfur cluster binding
BH372_RS09905	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BH372_RS09910	COG3473	Maleate cis-trans isomerase
BH372_RS09920	COG2309	aminopeptidase activity
BH372_RS09925	COG1335	isochorismatase
BH372_RS09940	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BH372_RS09940	COG1017	nitric oxide dioxygenase activity
BH372_RS09955	COG3181	Tripartite tricarboxylate transporter family receptor
BH372_RS09965	COG2197	response regulator
BH372_RS09980	COG0166	Belongs to the GPI family
BH372_RS09985	COG1045	serine acetyltransferase
BH372_RS09995	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BH372_RS10000	COG0483	inositol monophosphate 1-phosphatase activity
BH372_RS10005	COG1012	belongs to the aldehyde dehydrogenase family
BH372_RS10010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BH372_RS10030	COG0210	DNA helicase
BH372_RS10035	COG0598	Magnesium transport protein CorA
BH372_RS10045	COG0747	negative chemotaxis
BH372_RS10050	COG0601	transmembrane transport
BH372_RS10055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BH372_RS10060	COG4172	Belongs to the ABC transporter superfamily
BH372_RS10065	COG1846	Transcriptional regulator
BH372_RS10115	COG4964	Belongs to the GSP D family
BH372_RS10155	COG2204	response regulator
BH372_RS10170	COG1595	DNA-templated transcription, initiation
BH372_RS10180	COG3474	cytochrome
BH372_RS10185	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BH372_RS10200	COG3384	dioxygenase
BH372_RS10205	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BH372_RS10230	COG2885	chlorophyll binding
BH372_RS10265	COG0697	spore germination
BH372_RS10270	COG0730	response to heat
BH372_RS10285	COG0583	DNA-binding transcription factor activity
BH372_RS10290	COG0427	acetyl-CoA hydrolase
BH372_RS10345	COG1250	3-hydroxyacyl-CoA dehydrogenase
BH372_RS10350	COG0154	amidase activity
BH372_RS10360	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BH372_RS10375	COG0495	leucyl-tRNA aminoacylation
BH372_RS10380	COG2814	Major facilitator Superfamily
BH372_RS10405	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BH372_RS10410	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BH372_RS10415	COG2814	Major facilitator Superfamily
BH372_RS10435	COG4176	ABC-type proline glycine betaine transport system permease component
BH372_RS10445	COG1942	4-Oxalocrotonate Tautomerase
BH372_RS10450	COG0183	Belongs to the thiolase family
BH372_RS10460	COG1802	Transcriptional regulator
BH372_RS10470	COG1024	Enoyl-CoA hydratase
BH372_RS10485	COG2032	superoxide dismutase activity
BH372_RS10500	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BH372_RS10525	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BH372_RS10530	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BH372_RS10540	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BH372_RS10545	COG0736	holo-[acyl-carrier-protein] synthase activity
BH372_RS10550	COG1472	Belongs to the glycosyl hydrolase 3 family
BH372_RS10555	COG0322	excinuclease ABC activity
BH372_RS10560	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BH372_RS10575	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BH372_RS10575	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BH372_RS10580	COG2224	Isocitrate lyase
BH372_RS10600	COG0559	Belongs to the binding-protein-dependent transport system permease family
BH372_RS10610	COG4638	Rieske (2fe-2S)
BH372_RS10620	COG1024	Enoyl-CoA hydratase
BH372_RS10630	COG0633	Ferredoxin
BH372_RS10635	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH372_RS10650	COG0183	Belongs to the thiolase family
BH372_RS10665	COG0583	DNA-binding transcription factor activity
BH372_RS10690	COG2346	COG2346, Truncated hemoglobins
BH372_RS10820	COG2207	Transcriptional regulator
BH372_RS10865	COG1132	(ABC) transporter
BH372_RS10890	COG0659	secondary active sulfate transmembrane transporter activity
BH372_RS10920	COG2169	Transcriptional regulator
BH372_RS10925	COG5507	3-demethylubiquinone-9 3-methyltransferase
BH372_RS10930	COG0384	phenazine biosynthesis protein PhzF
BH372_RS10935	COG0583	DNA-binding transcription factor activity
BH372_RS10940	COG2733	membrane
BH372_RS10955	COG1012	belongs to the aldehyde dehydrogenase family
BH372_RS10960	COG3284	Transcriptional regulator
BH372_RS10980	COG1380	Effector of murein hydrolase LrgA
BH372_RS10985	COG4106	trans-aconitate 2-methyltransferase activity
BH372_RS10985	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BH372_RS10995	COG0156	8-amino-7-oxononanoate synthase activity
BH372_RS11065	COG1131	(ABC) transporter
BH372_RS11070	COG0842	Transport permease protein
BH372_RS11075	COG0628	permease
BH372_RS11105	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BH372_RS11115	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BH372_RS11125	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BH372_RS11130	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BH372_RS11135	COG0330	HflC and HflK could
BH372_RS11140	COG0330	HflC and HflK could
BH372_RS11145	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BH372_RS11150	COG1923	regulation of RNA biosynthetic process
BH372_RS11155	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BH372_RS11160	COG1160	GTP binding
BH372_RS11165	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BH372_RS11170	COG2976	Protein conserved in bacteria
BH372_RS11175	COG0124	histidyl-tRNA synthetase
BH372_RS11180	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BH372_RS11190	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BH372_RS11195	COG0105	UTP biosynthetic process
BH372_RS11200	COG0525	valine-tRNA ligase activity
BH372_RS11215	COG0642	Histidine kinase
BH372_RS11235	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BH372_RS11240	COG0336	Belongs to the RNA methyltransferase TrmD family
BH372_RS11245	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BH372_RS11250	COG0228	four-way junction DNA binding
BH372_RS11260	COG0425	Belongs to the sulfur carrier protein TusA family
BH372_RS11265	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BH372_RS11310	COG0154	amidase activity
BH372_RS11315	COG4172	Belongs to the ABC transporter superfamily
BH372_RS11320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BH372_RS11325	COG0601	transmembrane transport
BH372_RS11330	COG0747	negative chemotaxis
BH372_RS11355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BH372_RS11365	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BH372_RS11385	COG3395	kinase activity
BH372_RS11400	COG1024	Enoyl-CoA hydratase
BH372_RS11420	COG0633	Ferredoxin
BH372_RS11425	COG0443	Heat shock 70 kDa protein
BH372_RS11430	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BH372_RS11435	COG0316	Belongs to the HesB IscA family
BH372_RS11440	COG0822	iron-sulfur transferase activity
BH372_RS11445	COG1104	cysteine desulfurase activity
BH372_RS11455	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BH372_RS11460	COG0556	nucleotide-excision repair
BH372_RS11470	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BH372_RS11500	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BH372_RS11520	COG1028	Short-chain dehydrogenase reductase Sdr
BH372_RS11525	COG0183	Belongs to the thiolase family
BH372_RS11535	COG1024	Enoyl-CoA hydratase
BH372_RS11550	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH372_RS11555	COG0583	DNA-binding transcription factor activity
BH372_RS11560	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BH372_RS11565	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BH372_RS11570	COG0740	serine-type endopeptidase activity
BH372_RS11575	COG0544	peptidyl-prolyl cis-trans isomerase activity
BH372_RS11585	COG1278	Cold shock
BH372_RS11595	COG1278	Cold shock
BH372_RS11630	COG2171	N-acyltransferase activity
BH372_RS11635	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BH372_RS11640	COG2890	protein-(glutamine-N5) methyltransferase activity
BH372_RS11645	COG0488	(ABC) transporter
BH372_RS11650	COG4771	TonB-dependent receptor
BH372_RS11655	COG0210	DNA helicase
BH372_RS11675	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BH372_RS11680	COG0196	riboflavin kinase activity
BH372_RS11685	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BH372_RS11690	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BH372_RS11695	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BH372_RS11705	COG1522	sequence-specific DNA binding
BH372_RS11720	COG2951	lytic endotransglycosylase activity
BH372_RS11725	COG2833	Protein of unknown function (DUF455)
BH372_RS11745	COG0189	ligase activity
BH372_RS11745	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BH372_RS11750	COG1181	Belongs to the D-alanine--D-alanine ligase family
BH372_RS11750	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BH372_RS11755	COG3237	CsbD-like
BH372_RS11765	COG2823	Periplasmic or secreted lipoprotein
BH372_RS11785	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BH372_RS11790	COG0584	glycerophosphoryl diester phosphodiesterase
BH372_RS11795	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BH372_RS11805	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BH372_RS11805	COG0678	peroxiredoxin activity
BH372_RS11815	COG0789	Transcriptional regulator
BH372_RS11820	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BH372_RS11850	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BH372_RS11855	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BH372_RS11865	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BH372_RS11870	COG2252	PERMEase
BH372_RS11880	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BH372_RS11915	COG0488	(ABC) transporter
BH372_RS11920	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BH372_RS11935	COG1024	Enoyl-CoA hydratase
BH372_RS11940	COG1619	proteins homologs of microcin C7 resistance protein MccF
BH372_RS11945	COG0590	tRNA wobble adenosine to inosine editing
BH372_RS11970	COG2212	antiporter activity
BH372_RS11975	COG1863	multisubunit Na H antiporter MnhE subunit
BH372_RS11980	COG0651	ATP synthesis coupled electron transport
BH372_RS11985	COG1006	Multisubunit Na H antiporter MnhC subunit
BH372_RS11990	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BH372_RS11990	COG2111	Na H antiporter
BH372_RS12010	COG0583	DNA-binding transcription factor activity
BH372_RS12015	COG1028	Short-chain dehydrogenase reductase Sdr
BH372_RS12045	COG0431	NADPH-dependent FMN reductase
BH372_RS12090	COG1028	Short-chain dehydrogenase reductase Sdr
BH372_RS12095	COG0179	Fumarylacetoacetate (FAA) hydrolase
BH372_RS12125	COG0625	glutathione transferase activity
BH372_RS12135	COG2944	sequence-specific DNA binding
BH372_RS12145	COG2197	response regulator
BH372_RS12170	COG3119	arylsulfatase activity
BH372_RS12200	COG0714	Associated with various cellular activities
BH372_RS12220	COG1028	Short-chain dehydrogenase reductase Sdr
BH372_RS12225	COG0861	Integral membrane protein TerC family
BH372_RS12270	COG0300	oxidoreductase activity
BH372_RS12295	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BH372_RS12310	COG0438	transferase activity, transferring glycosyl groups
BH372_RS12345	COG0783	Belongs to the Dps family
BH372_RS12360	COG0583	DNA-binding transcription factor activity
BH372_RS12365	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BH372_RS12380	COG0656	L-ascorbic acid biosynthetic process
BH372_RS12390	COG0583	DNA-binding transcription factor activity
BH372_RS12400	COG1840	ABC-type Fe3 transport system, periplasmic component
BH372_RS12405	COG1178	ABC-type Fe3 transport system permease component
BH372_RS12410	COG3842	ATPase activity
BH372_RS12420	COG1741	Belongs to the pirin family
BH372_RS12425	COG1741	Belongs to the pirin family
BH372_RS12430	COG0583	DNA-binding transcription factor activity
BH372_RS12435	COG2204	response regulator
BH372_RS12445	COG0174	glutamine synthetase
BH372_RS12450	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BH372_RS12460	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BH372_RS12465	COG2200	EAL domain
BH372_RS12465	COG2199	diguanylate cyclase activity
BH372_RS12490	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BH372_RS12495	COG1561	YicC-like family, N-terminal region
BH372_RS12515	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BH372_RS12520	COG0791	NLP P60 protein
BH372_RS12525	COG1028	Short-chain dehydrogenase reductase Sdr
BH372_RS12530	COG2863	cytochrome
BH372_RS12535	COG3258	Cytochrome c
BH372_RS12540	COG0194	GDP metabolic process
BH372_RS12545	COG1758	RNA polymerase activity
BH372_RS12550	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BH372_RS12555	COG1126	abc transporter atp-binding protein
BH372_RS12560	COG0765	amino acid transport
BH372_RS12565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BH372_RS12580	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BH372_RS12585	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BH372_RS12590	COG3539	Fimbrial protein
BH372_RS12595	COG2850	peptidyl-arginine hydroxylation
BH372_RS12600	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BH372_RS12605	COG3360	Dodecin
BH372_RS12645	COG0009	L-threonylcarbamoyladenylate synthase
BH372_RS12650	COG2321	neutral zinc metallopeptidase
BH372_RS12670	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BH372_RS12675	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BH372_RS12680	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BH372_RS12690	COG1074	ATP-dependent DNA helicase activity
BH372_RS12700	COG2814	Major facilitator Superfamily
BH372_RS12710	COG1686	Belongs to the peptidase S11 family
BH372_RS12725	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BH372_RS12730	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BH372_RS12735	COG4974	Belongs to the 'phage' integrase family
BH372_RS12740	COG0583	DNA-binding transcription factor activity
BH372_RS12745	COG0028	Belongs to the TPP enzyme family
BH372_RS12760	COG0028	Belongs to the TPP enzyme family
BH372_RS12765	COG1126	abc transporter atp-binding protein
BH372_RS12770	COG0765	amino acid transport
BH372_RS12785	COG1414	Transcriptional regulator
BH372_RS12790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BH372_RS12795	COG0009	L-threonylcarbamoyladenylate synthase
BH372_RS12800	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BH372_RS12805	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BH372_RS12810	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BH372_RS12815	COG2944	sequence-specific DNA binding
BH372_RS12825	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BH372_RS12880	COG1126	abc transporter atp-binding protein
BH372_RS12885	COG0765	amino acid transport
BH372_RS12890	COG0765	amino acid transport
BH372_RS12895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BH372_RS12905	COG2423	ornithine cyclodeaminase activity
BH372_RS12915	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BH372_RS12920	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BH372_RS12930	COG0189	ligase activity
BH372_RS12935	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BH372_RS12940	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BH372_RS12945	COG2197	response regulator
BH372_RS12965	COG3706	GGDEF domain
BH372_RS12975	COG1028	Short-chain dehydrogenase reductase Sdr
BH372_RS12990	COG3486	L-lysine 6-monooxygenase (NADPH) activity
BH372_RS13020	COG2814	Major facilitator Superfamily
BH372_RS13040	COG3706	GGDEF domain
BH372_RS13065	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BH372_RS13070	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BH372_RS13075	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BH372_RS13080	COG1674	ftsk spoiiie
BH372_RS13085	COG0492	ferredoxin-NADP+ reductase activity
BH372_RS13090	COG1193	negative regulation of DNA recombination
BH372_RS13105	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BH372_RS13120	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BH372_RS13125	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BH372_RS13130	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
BH372_RS13140	COG0745	RESPONSE REGULATOR receiver
BH372_RS13185	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BH372_RS13205	COG0612	Peptidase, M16
BH372_RS13215	COG0443	Heat shock 70 kDa protein
BH372_RS13225	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BH372_RS13235	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BH372_RS13240	COG1420	regulation of RNA biosynthetic process
BH372_RS13245	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BH372_RS13250	COG0497	DNA recombination
BH372_RS13255	COG0735	belongs to the Fur family
BH372_RS13260	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BH372_RS13265	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BH372_RS13270	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BH372_RS13305	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BH372_RS13305	COG0446	pyridine nucleotide-disulphide oxidoreductase
BH372_RS13310	COG4311	Sarcosine oxidase, delta subunit
BH372_RS13315	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BH372_RS13325	COG0583	DNA-binding transcription factor activity
BH372_RS13335	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BH372_RS13365	COG4964	Belongs to the GSP D family
BH372_RS13425	COG0181	hydroxymethylbilane synthase activity
BH372_RS13430	COG0861	Integral membrane protein TerC family
BH372_RS13435	COG0861	Integral membrane protein TerC family
BH372_RS13440	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BH372_RS13445	COG0045	succinate-CoA ligase (ADP-forming) activity
BH372_RS13455	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BH372_RS13465	COG2137	regulation of response to DNA damage stimulus
BH372_RS13470	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BH372_RS13480	COG0642	Histidine kinase
BH372_RS13490	COG1250	3-hydroxyacyl-CoA dehydrogenase
BH372_RS13490	COG1024	Enoyl-CoA hydratase
BH372_RS13495	COG3842	ATPase activity
BH372_RS13510	COG1028	Short-chain dehydrogenase reductase Sdr
BH372_RS13530	COG0583	DNA-binding transcription factor activity
BH372_RS13535	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH372_RS13545	COG2974	May be involved in recombination
BH372_RS13550	COG0540	Belongs to the ATCase OTCase family
BH372_RS13620	COG0776	regulation of translation
BH372_RS13625	COG0072	phenylalanine-tRNA ligase activity
BH372_RS13625	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BH372_RS13630	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BH372_RS13635	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BH372_RS13640	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BH372_RS13650	COG0756	dUTP diphosphatase activity
BH372_RS13660	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BH372_RS13675	COG0500	methyltransferase
BH372_RS13685	COG0586	Pfam SNARE associated Golgi protein
BH372_RS13710	COG1609	Transcriptional regulator
BH372_RS13715	COG4172	Belongs to the ABC transporter superfamily
BH372_RS13725	COG0601	transmembrane transport
BH372_RS13730	COG0747	negative chemotaxis
BH372_RS13750	COG1280	lysine exporter protein (LysE YggA)
BH372_RS13765	COG2814	Major facilitator Superfamily
BH372_RS13795	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BH372_RS13810	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BH372_RS13845	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BH372_RS13850	COG1116	anion transmembrane transporter activity
BH372_RS13860	COG1228	amidohydrolase
BH372_RS13875	COG0477	Major facilitator Superfamily
BH372_RS13885	COG3550	peptidyl-serine autophosphorylation
BH372_RS13895	COG0519	Catalyzes the synthesis of GMP from XMP
BH372_RS13895	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BH372_RS13945	COG0420	3'-5' exonuclease activity
BH372_RS13950	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BH372_RS13980	COG0395	ABC-type sugar transport system, permease component
BH372_RS14020	COG3181	Tripartite tricarboxylate transporter family receptor
BH372_RS14055	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BH372_RS14080	COG0602	queuosine metabolic process
BH372_RS14085	COG0720	synthase
BH372_RS14090	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BH372_RS14095	COG0235	Class ii aldolase
BH372_RS14120	COG3064	Membrane
BH372_RS14120	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
BH372_RS14120	COG3210	domain, Protein
BH372_RS14125	COG0047	phosphoribosylformylglycinamidine synthase activity
BH372_RS14125	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BH372_RS14130	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BH372_RS14135	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BH372_RS14140	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BH372_RS14155	COG3539	Fimbrial protein
BH372_RS14165	COG2050	protein possibly involved in aromatic compounds catabolism
BH372_RS14170	COG1024	Enoyl-CoA hydratase
BH372_RS14175	COG1012	belongs to the aldehyde dehydrogenase family
BH372_RS14185	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BH372_RS14190	COG2151	metal-sulfur cluster biosynthetic enzyme
BH372_RS14195	COG3396	Phenylacetate-CoA oxygenase
BH372_RS14200	COG3460	Phenylacetate-CoA oxygenase
BH372_RS14205	COG3396	Phenylacetate-CoA oxygenase
BH372_RS14210	COG3327	negative regulation of DNA-templated transcription, initiation
BH372_RS14220	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BH372_RS14225	COG0501	Belongs to the peptidase M48B family
BH372_RS14230	COG1162	GTPase activity
BH372_RS14240	COG0601	transmembrane transport
BH372_RS14245	COG0747	negative chemotaxis
BH372_RS14290	COG0668	transmembrane transport
BH372_RS14295	COG0165	Argininosuccinate lyase
BH372_RS14315	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BH372_RS14320	COG0303	'Molybdopterin
BH372_RS14325	COG0521	Mo-molybdopterin cofactor biosynthetic process
BH372_RS14340	COG0315	cyclic pyranopterin monophosphate synthase activity
BH372_RS14350	COG0412	Dienelactone hydrolase
BH372_RS14360	COG0678	peroxiredoxin activity
BH372_RS14370	COG0697	spore germination
BH372_RS14375	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BH372_RS14400	COG0789	Transcriptional regulator
BH372_RS14420	COG1028	Short-chain dehydrogenase reductase Sdr
BH372_RS14430	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BH372_RS14435	COG1845	cytochrome c oxidase, subunit III
BH372_RS14440	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BH372_RS14450	COG0477	Major facilitator Superfamily
BH372_RS14490	COG1309	transcriptional regulator
BH372_RS14495	COG2271	Major facilitator Superfamily
BH372_RS14530	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BH372_RS14530	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BH372_RS14530	COG0506	proline dehydrogenase activity
BH372_RS14540	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BH372_RS14540	COG3008	intermembrane lipid transfer
BH372_RS14545	COG2995	paraquat-inducible protein a
BH372_RS14550	COG0542	response to heat
BH372_RS14555	COG4953	penicillin-binding protein 1C
BH372_RS14565	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BH372_RS14570	COG1278	Cold shock
BH372_RS14580	COG0183	Belongs to the thiolase family
BH372_RS14585	COG0038	chloride channel
BH372_RS14590	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BH372_RS14595	COG1570	exodeoxyribonuclease VII activity
BH372_RS14605	COG0811	peptide transport
BH372_RS14610	COG0848	biopolymer transport protein
BH372_RS14615	COG1663	tetraacyldisaccharide 4'-kinase activity
BH372_RS14620	COG2835	tetraacyldisaccharide 4'-kinase activity
BH372_RS14625	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BH372_RS14630	COG0563	adenylate kinase activity
BH372_RS14640	COG0728	peptidoglycan biosynthetic process
BH372_RS14650	COG0268	Binds directly to 16S ribosomal RNA
BH372_RS14680	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BH372_RS14705	COG0436	Aminotransferase
BH372_RS14710	COG3737	Protein of unknown function (DUF498/DUF598)
BH372_RS14715	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BH372_RS14720	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BH372_RS14725	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BH372_RS14735	COG0305	Participates in initiation and elongation during chromosome replication
BH372_RS14745	COG0359	binds to the 23S rRNA
BH372_RS14750	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BH372_RS14755	COG2965	DNA replication, synthesis of RNA primer
BH372_RS14760	COG0360	Binds together with S18 to 16S ribosomal RNA
BH372_RS14765	COG1469	GTP cyclohydrolase I activity
BH372_RS14770	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BH372_RS14775	COG0142	geranyltranstransferase activity
BH372_RS14780	COG1722	exodeoxyribonuclease VII activity
BH372_RS14790	COG3181	Tripartite tricarboxylate transporter family receptor
BH372_RS14810	COG2239	Acts as a magnesium transporter
BH372_RS14820	COG2855	membrane
BH372_RS14830	COG1473	amidohydrolase
BH372_RS14835	COG0318	PFAM AMP-dependent synthetase and ligase
BH372_RS14855	COG1501	Belongs to the glycosyl hydrolase 31 family
BH372_RS14860	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BH372_RS14865	COG2011	ABC-type metal ion transport system permease component
BH372_RS14885	COG1454	alcohol dehydrogenase
BH372_RS14910	COG2186	Transcriptional regulator
BH372_RS14915	COG3181	Tripartite tricarboxylate transporter family receptor
BH372_RS14935	COG1175	transmembrane transport
BH372_RS14940	COG0395	ABC-type sugar transport system, permease component
BH372_RS14945	COG3842	ATPase activity
BH372_RS14960	COG1653	transport
BH372_RS14980	COG2818	Glycosylase
BH372_RS14985	COG2982	Protein involved in outer membrane biogenesis
BH372_RS14995	COG1309	transcriptional regulator
BH372_RS15000	COG1028	Short-chain dehydrogenase reductase Sdr
BH372_RS15040	COG0583	DNA-binding transcription factor activity
BH372_RS15045	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BH372_RS15050	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BH372_RS15065	COG1028	Short-chain dehydrogenase reductase Sdr
BH372_RS15070	COG0477	Major facilitator Superfamily
BH372_RS15080	COG0583	DNA-binding transcription factor activity
BH372_RS15085	COG1448	Aminotransferase
BH372_RS15090	COG1418	mRNA catabolic process
BH372_RS15115	COG1063	alcohol dehydrogenase
BH372_RS15135	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BH372_RS15145	COG0318	PFAM AMP-dependent synthetase and ligase
BH372_RS15155	COG1522	sequence-specific DNA binding
BH372_RS15160	COG3181	Tripartite tricarboxylate transporter family receptor
BH372_RS15165	COG0307	riboflavin synthase, alpha
BH372_RS15170	COG0154	amidase activity
BH372_RS15190	COG2807	transmembrane transport
BH372_RS15195	COG0590	tRNA wobble adenosine to inosine editing
BH372_RS15205	COG0583	DNA-binding transcription factor activity
BH372_RS15240	COG0559	Belongs to the binding-protein-dependent transport system permease family
BH372_RS15245	COG0251	oxidation-reduction process
BH372_RS15260	COG1414	Transcriptional regulator
BH372_RS15265	COG1028	Short-chain dehydrogenase reductase Sdr
BH372_RS15280	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BH372_RS15295	COG1024	Enoyl-CoA hydratase
BH372_RS15300	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH372_RS15345	COG3909	cytochrome
BH372_RS15350	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BH372_RS15355	COG0625	glutathione transferase activity
BH372_RS15360	COG0730	response to heat
BH372_RS15365	COG0482	sulfurtransferase activity
BH372_RS15370	COG0583	DNA-binding transcription factor activity
BH372_RS15405	COG2819	hydrolase of the alpha beta superfamily
BH372_RS15410	COG0247	lactate metabolic process
BH372_RS15415	COG0277	FAD linked oxidase domain protein
BH372_RS15420	COG0277	FAD linked oxidase domain protein
BH372_RS15425	COG0277	FAD linked oxidase domain protein
BH372_RS15430	COG3064	Membrane
BH372_RS15430	COG3210	domain, Protein
BH372_RS15430	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
BH372_RS15430	COG3210	domain, Protein
BH372_RS15430	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
BH372_RS15430	COG3064	Membrane
BH372_RS15435	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BH372_RS15440	COG0312	modulator of DNA gyrase
BH372_RS15475	COG1666	GTP binding
BH372_RS15520	COG3220	belongs to the UPF0276 family
BH372_RS15540	COG0640	Transcriptional regulator
BH372_RS15545	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BH372_RS15550	COG1845	cytochrome c oxidase, subunit III
BH372_RS15555	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BH372_RS15565	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BH372_RS15605	COG0583	DNA-binding transcription factor activity
BH372_RS15635	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BH372_RS15635	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BH372_RS15650	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BH372_RS15655	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BH372_RS15665	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BH372_RS15680	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BH372_RS15685	COG0316	Belongs to the HesB IscA family
BH372_RS15695	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BH372_RS15700	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BH372_RS15705	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BH372_RS15710	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BH372_RS15715	COG0312	modulator of DNA gyrase
BH372_RS15720	COG3028	Belongs to the UPF0307 family
BH372_RS15735	COG1116	anion transmembrane transporter activity
BH372_RS15740	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BH372_RS15745	COG1335	isochorismatase
BH372_RS15750	COG0346	lactoylglutathione lyase activity
BH372_RS15755	COG0513	Belongs to the DEAD box helicase family
BH372_RS15760	COG3069	C4-dicarboxylate transmembrane transporter activity
BH372_RS15765	COG1802	Transcriptional regulator
BH372_RS15775	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BH372_RS15775	COG1042	CoA-binding domain protein
BH372_RS15775	COG0045	succinate-CoA ligase (ADP-forming) activity
BH372_RS15780	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BH372_RS15795	COG1522	sequence-specific DNA binding
BH372_RS15830	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BH372_RS15835	COG1696	Membrane protein involved in D-alanine export
BH372_RS15860	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BH372_RS15875	COG0439	Biotin carboxylase
BH372_RS15880	COG0511	ligase activity, forming carbon-carbon bonds
BH372_RS15885	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BH372_RS15890	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BH372_RS15895	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BH372_RS15900	COG3150	esterase
BH372_RS15905	COG0557	exoribonuclease II activity
BH372_RS15915	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BH372_RS15935	COG1522	sequence-specific DNA binding
BH372_RS15940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BH372_RS15945	COG1028	Short-chain dehydrogenase reductase Sdr
BH372_RS15965	COG0653	protein targeting
BH372_RS15970	COG0739	heme binding
BH372_RS15980	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BH372_RS15985	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BH372_RS15995	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BH372_RS16000	COG1181	Belongs to the D-alanine--D-alanine ligase family
BH372_RS16005	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BH372_RS16010	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BH372_RS16020	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BH372_RS16025	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BH372_RS16030	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BH372_RS16040	COG3116	cell division
BH372_RS16045	COG0275	rRNA processing
BH372_RS16050	COG2001	Belongs to the MraZ family
BH372_RS16065	COG0418	dihydroorotase activity
BH372_RS16070	COG1473	amidohydrolase
BH372_RS16120	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BH372_RS16125	COG4654	Cytochrome c, class I
BH372_RS16130	COG0129	dihydroxy-acid dehydratase activity
BH372_RS16135	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BH372_RS16185	COG2084	Dehydrogenase
BH372_RS16200	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BH372_RS16205	COG0513	Belongs to the DEAD box helicase family
BH372_RS16215	COG0617	tRNA 3'-terminal CCA addition
BH372_RS16230	COG0477	Major facilitator Superfamily
BH372_RS16240	COG0583	DNA-binding transcription factor activity
BH372_RS16255	COG1950	PFAM Membrane protein of
BH372_RS16260	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BH372_RS16275	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BH372_RS16285	COG1560	Kdo2-lipid A biosynthetic process
BH372_RS16290	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BH372_RS16300	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BH372_RS16310	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
BH372_RS16320	COG0803	Belongs to the bacterial solute-binding protein 9 family
BH372_RS16340	COG0735	belongs to the Fur family
BH372_RS16345	COG0523	cobalamin synthesis protein
BH372_RS16355	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BH372_RS16360	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BH372_RS16370	COG2096	Adenosyltransferase
BH372_RS16385	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BH372_RS16390	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BH372_RS16435	COG4772	TonB-dependent receptor
BH372_RS16465	COG0405	Gamma-glutamyltransferase
BH372_RS16475	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BH372_RS16500	COG1309	transcriptional regulator
BH372_RS16515	COG0745	RESPONSE REGULATOR receiver
BH372_RS16565	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BH372_RS16585	COG0582	viral genome integration into host DNA
BH372_RS16590	COG0012	GTP binding
BH372_RS16600	COG0193	aminoacyl-tRNA hydrolase activity
BH372_RS16605	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BH372_RS16610	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BH372_RS16620	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BH372_RS16625	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BH372_RS16635	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BH372_RS16660	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
BH372_RS16670	COG1368	sulfuric ester hydrolase activity
BH372_RS16675	COG0642	Histidine kinase
BH372_RS16680	COG0745	RESPONSE REGULATOR receiver
BH372_RS16685	COG0277	FAD linked oxidase domain protein
BH372_RS16700	COG0166	Belongs to the GPI family
BH372_RS16705	COG0438	transferase activity, transferring glycosyl groups
BH372_RS16710	COG0438	transferase activity, transferring glycosyl groups
BH372_RS16725	COG0438	transferase activity, transferring glycosyl groups
BH372_RS16740	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BH372_RS16745	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BH372_RS16750	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
BH372_RS16760	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BH372_RS16770	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BH372_RS16785	COG0747	negative chemotaxis
BH372_RS16790	COG0601	transmembrane transport
BH372_RS16795	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BH372_RS16815	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BH372_RS16820	COG0830	nickel cation binding
BH372_RS16830	COG0804	urea catabolic process
BH372_RS16835	COG0832	Belongs to the urease beta subunit family
BH372_RS16845	COG0831	urea catabolic process
BH372_RS16850	COG0829	nickel cation binding
BH372_RS16875	COG2188	Transcriptional regulator
BH372_RS16900	COG2719	SpoVR family
BH372_RS16905	COG2718	Belongs to the UPF0229 family
BH372_RS16925	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH372_RS16940	COG1960	acyl-CoA dehydrogenase activity
BH372_RS16990	COG2030	dehydratase
BH372_RS17050	COG0328	RNA-DNA hybrid ribonuclease activity
BH372_RS17055	COG2226	methyltransferase
BH372_RS17060	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BH372_RS17065	COG1388	LysM domain
BH372_RS17065	COG0741	lytic transglycosylase activity
BH372_RS17085	COG2979	Protein of unknown function (DUF533)
BH372_RS17105	COG0745	RESPONSE REGULATOR receiver
BH372_RS17120	COG1271	oxidase subunit
BH372_RS17125	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BH372_RS17130	COG0850	regulation of cytokinetic process
BH372_RS17135	COG2894	cell division
BH372_RS17140	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BH372_RS17170	COG0601	transmembrane transport
BH372_RS17180	COG1215	transferase activity, transferring glycosyl groups
BH372_RS17195	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BH372_RS17205	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BH372_RS17225	COG0318	PFAM AMP-dependent synthetase and ligase
BH372_RS17230	COG2188	Transcriptional regulator
BH372_RS17235	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BH372_RS17240	COG2814	Major facilitator Superfamily
BH372_RS17250	COG0259	pyridoxamine-phosphate oxidase activity
BH372_RS17255	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BH372_RS17270	COG0583	DNA-binding transcription factor activity
BH372_RS17300	COG0134	indole-3-glycerol-phosphate synthase activity
BH372_RS17305	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BH372_RS17310	COG0512	Glutamine amidotransferase of anthranilate synthase
BH372_RS17320	COG0546	phosphoglycolate phosphatase activity
BH372_RS17325	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BH372_RS17330	COG2967	ApaG domain
BH372_RS17335	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
BH372_RS17340	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BH372_RS17345	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BH372_RS17350	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BH372_RS17360	COG0037	tRNA processing
BH372_RS17370	COG3634	alkyl hydroperoxide reductase activity
BH372_RS17375	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BH372_RS17380	COG1024	Enoyl-CoA hydratase
BH372_RS17405	COG0356	it plays a direct role in the translocation of protons across the membrane
BH372_RS17415	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BH372_RS17420	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BH372_RS17425	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BH372_RS17430	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BH372_RS17435	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BH372_RS17440	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BH372_RS17450	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BH372_RS17455	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BH372_RS17460	COG0210	DNA helicase
BH372_RS17470	COG2195	Cleaves the N-terminal amino acid of tripeptides
BH372_RS17485	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BH372_RS17490	COG0601	transmembrane transport
BH372_RS17510	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BH372_RS17515	COG1024	Enoyl-CoA hydratase
BH372_RS17520	COG1024	Enoyl-CoA hydratase
BH372_RS17575	COG2132	Multicopper oxidase
BH372_RS17585	COG1024	Enoyl-CoA hydratase
BH372_RS17585	COG1250	3-hydroxyacyl-CoA dehydrogenase
BH372_RS17610	COG0154	amidase activity
BH372_RS17640	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BH372_RS17645	COG3568	Endonuclease Exonuclease Phosphatase
BH372_RS17650	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BH372_RS17685	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BH372_RS17695	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BH372_RS17710	COG1137	ATPase activity
BH372_RS17725	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BH372_RS17730	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BH372_RS17730	COG2010	Cytochrome c
BH372_RS17740	COG1660	Displays ATPase and GTPase activities
BH372_RS17745	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BH372_RS17785	COG3181	Tripartite tricarboxylate transporter family receptor
BH372_RS17795	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BH372_RS17800	COG2890	protein-(glutamine-N5) methyltransferase activity
BH372_RS17805	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BH372_RS17810	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BH372_RS17850	COG1960	acyl-CoA dehydrogenase activity
BH372_RS17860	COG0183	Belongs to the thiolase family
BH372_RS17865	COG1522	sequence-specific DNA binding
BH372_RS17870	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BH372_RS17890	COG1024	Enoyl-CoA hydratase
BH372_RS17905	COG0604	alcohol dehydrogenase
BH372_RS17910	COG2072	flavoprotein involved in K transport
BH372_RS17925	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BH372_RS17935	COG1960	acyl-CoA dehydrogenase activity
BH372_RS17940	COG1960	acyl-CoA dehydrogenase activity
BH372_RS17945	COG0277	FAD linked oxidase domain protein
BH372_RS17955	COG3181	Tripartite tricarboxylate transporter family receptor
BH372_RS17975	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BH372_RS17985	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH372_RS17990	COG3181	Tripartite tricarboxylate transporter family receptor
BH372_RS17995	COG1960	acyl-CoA dehydrogenase activity
BH372_RS18015	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BH372_RS18020	COG1024	Enoyl-CoA hydratase
BH372_RS18025	COG1960	acyl-CoA dehydrogenase activity
BH372_RS18045	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BH372_RS18050	COG0022	dehydrogenase e1 component
BH372_RS18055	COG1024	Enoyl-CoA hydratase
BH372_RS18060	COG0508	dehydrogenase complex catalyzes the overall conversion of
BH372_RS18080	COG0683	leucine binding
BH372_RS18085	COG0559	Belongs to the binding-protein-dependent transport system permease family
BH372_RS18090	COG0411	ABC transporter
BH372_RS18100	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BH372_RS18115	COG3181	Tripartite tricarboxylate transporter family receptor
BH372_RS18140	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BH372_RS18145	COG0793	Belongs to the peptidase S41A family
BH372_RS18150	COG4942	peptidase
BH372_RS18155	COG0588	phosphoglycerate mutase activity
BH372_RS18165	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BH372_RS18170	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BH372_RS18175	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BH372_RS18180	COG3181	Tripartite tricarboxylate transporter family receptor
BH372_RS18195	COG2226	methyltransferase
BH372_RS18200	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
BH372_RS18215	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BH372_RS18220	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BH372_RS18245	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BH372_RS18270	COG1335	isochorismatase
BH372_RS18275	COG2309	aminopeptidase activity
BH372_RS18285	COG3473	Maleate cis-trans isomerase
BH372_RS18295	COG2068	MobA-Related Protein
BH372_RS18320	COG2204	response regulator
BH372_RS18325	COG5000	phosphorelay sensor kinase activity
BH372_RS18335	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BH372_RS18335	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BH372_RS18345	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
BH372_RS18370	COG0583	DNA-binding transcription factor activity
BH372_RS18390	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BH372_RS18395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BH372_RS18410	COG0758	DNA mediated transformation
BH372_RS18415	COG1522	sequence-specific DNA binding
BH372_RS18425	COG0242	peptide deformylase activity
BH372_RS18435	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BH372_RS18445	COG0546	phosphoglycolate phosphatase activity
BH372_RS18465	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BH372_RS18470	COG1942	4-Oxalocrotonate Tautomerase
BH372_RS18475	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BH372_RS18495	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BH372_RS18515	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BH372_RS18520	COG1024	Enoyl-CoA hydratase
BH372_RS18525	COG1414	Transcriptional regulator
BH372_RS18530	COG0318	PFAM AMP-dependent synthetase and ligase
BH372_RS18535	COG3181	Tripartite tricarboxylate transporter family receptor
BH372_RS18580	COG3422	double-strand break repair
BH372_RS18585	COG0330	HflC and HflK could
BH372_RS18595	COG0251	oxidation-reduction process
BH372_RS18640	COG3723	Recombinational DNA repair protein, rece pathway
BH372_RS18675	COG0582	viral genome integration into host DNA
BH372_RS18710	COG0706	membrane insertase activity
BH372_RS18715	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BH372_RS18720	COG0594	ribonuclease P activity
BH372_RS18725	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BH372_RS18730	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BH372_RS18745	COG1414	Transcriptional regulator
BH372_RS18750	COG0154	amidase activity
BH372_RS18765	COG1304	FMN binding
BH372_RS18815	COG0183	Belongs to the thiolase family
BH372_RS18820	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BH372_RS18835	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BH372_RS18840	COG3181	Tripartite tricarboxylate transporter family receptor
BH372_RS18850	COG2358	TRAP transporter, solute receptor (TAXI family
BH372_RS18860	COG1629	transport
BH372_RS18865	COG2922	Belongs to the Smg family
BH372_RS18890	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BH372_RS18895	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BH372_RS18900	COG1028	Short-chain dehydrogenase reductase Sdr
BH372_RS18905	COG1012	belongs to the aldehyde dehydrogenase family
BH372_RS18915	COG0028	Belongs to the TPP enzyme family
BH372_RS18920	COG1522	sequence-specific DNA binding
BH372_RS18925	COG3781	membrane
BH372_RS18935	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BH372_RS18955	COG4206	TonB-dependent receptor
BH372_RS18960	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BH372_RS18965	COG2022	thiamine diphosphate biosynthetic process
BH372_RS18970	COG0351	phosphomethylpyrimidine kinase
BH372_RS18975	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BH372_RS18990	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BH372_RS19000	COG0628	permease
BH372_RS19010	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BH372_RS19025	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BH372_RS19030	COG0049	tRNA binding
BH372_RS19035	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BH372_RS19040	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BH372_RS19045	COG0051	transcription antitermination factor activity, RNA binding
BH372_RS19050	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BH372_RS19055	COG0088	Forms part of the polypeptide exit tunnel
BH372_RS19060	COG0089	rRNA binding
BH372_RS19065	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BH372_RS19070	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BH372_RS19075	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BH372_RS19080	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BH372_RS19085	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BH372_RS19090	COG0255	Belongs to the universal ribosomal protein uL29 family
BH372_RS19095	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BH372_RS19115	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BH372_RS19120	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BH372_RS19125	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BH372_RS19130	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BH372_RS19135	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BH372_RS19140	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BH372_RS19145	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BH372_RS19150	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BH372_RS19155	COG1841	ribosomal large subunit assembly
BH372_RS19160	COG0200	Binds to the 23S rRNA
BH372_RS19165	COG0201	protein transport
BH372_RS19170	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BH372_RS19175	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BH372_RS19180	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BH372_RS19185	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BH372_RS19190	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BH372_RS19195	COG0202	RNA polymerase activity
BH372_RS19200	COG0203	ribosomal protein L17
BH372_RS19210	COG1324	tolerance protein
BH372_RS19215	COG4232	protein-disulfide reductase activity
BH372_RS19230	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BH372_RS19240	COG1333	cytochrome c biogenesis protein
BH372_RS19245	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BH372_RS19255	COG1965	Belongs to the frataxin family
BH372_RS19265	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BH372_RS19270	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BH372_RS19275	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BH372_RS19290	COG2814	Major facilitator Superfamily
BH372_RS19295	COG0629	single-stranded DNA binding
BH372_RS19335	COG0402	S-adenosylhomocysteine deaminase activity
BH372_RS19345	COG0438	transferase activity, transferring glycosyl groups
BH372_RS19365	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BH372_RS19390	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BH372_RS19415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BH372_RS19420	COG1956	GAF domain-containing protein
BH372_RS19425	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BH372_RS19435	COG1652	LysM domain
BH372_RS19450	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BH372_RS19465	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BH372_RS19490	COG3181	Tripartite tricarboxylate transporter family receptor
BH372_RS19505	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BH372_RS19520	COG1024	Enoyl-CoA hydratase
BH372_RS19535	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH372_RS19540	COG1309	transcriptional regulator
BH372_RS19545	COG2816	NAD+ diphosphatase activity
BH372_RS19550	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BH372_RS19635	COG2814	Major facilitator Superfamily
BH372_RS19640	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BH372_RS19660	COG1999	signal sequence binding
BH372_RS19665	COG0109	protoheme IX farnesyltransferase activity
BH372_RS19705	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BH372_RS19725	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BH372_RS19730	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BH372_RS19740	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BH372_RS19745	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
BH372_RS19755	COG0067	glutamate synthase
BH372_RS19755	COG0069	glutamate synthase activity
BH372_RS19755	COG0070	glutamate synthase
BH372_RS19765	COG3047	cAMP biosynthetic process
BH372_RS19775	COG1127	ABC transporter
BH372_RS19780	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BH372_RS19785	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BH372_RS19790	COG2853	Lipoprotein
BH372_RS19805	COG0842	Transport permease protein
BH372_RS19815	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BH372_RS19820	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BH372_RS19825	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BH372_RS19830	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BH372_RS19835	COG0131	Imidazoleglycerol-phosphate dehydratase
BH372_RS19840	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BH372_RS19845	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BH372_RS19850	COG0107	imidazoleglycerol-phosphate synthase activity
BH372_RS19855	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BH372_RS19860	COG0140	phosphoribosyl-ATP diphosphatase activity
BH372_RS19865	COG0537	adenosine 5'-monophosphoramidase activity
BH372_RS19870	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BH372_RS19875	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BH372_RS19890	COG3181	Tripartite tricarboxylate transporter family receptor
BH372_RS19925	COG3702	type iv secretory pathway
BH372_RS19930	COG3451	type IV secretory pathway VirB4
BH372_RS19945	COG3736	Type IV secretory pathway, component VirB8
BH372_RS19950	COG3504	Conjugal transfer protein
BH372_RS19955	COG2948	multi-organism process
BH372_RS19960	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
BH372_RS19970	COG0697	spore germination
BH372_RS19990	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BH372_RS19995	COG0747	negative chemotaxis
BH372_RS20005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BH372_RS20020	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BH372_RS20030	COG0494	nUDIX hydrolase
BH372_RS20070	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
BH372_RS20075	COG0237	dephospho-CoA kinase activity
BH372_RS20080	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BH372_RS20095	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BH372_RS20100	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BH372_RS20110	COG0477	Major facilitator Superfamily
BH372_RS20115	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BH372_RS20130	COG1126	abc transporter atp-binding protein
BH372_RS20135	COG0765	amino acid transport
BH372_RS20140	COG4597	amino acid ABC transporter
BH372_RS20145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BH372_RS20150	COG2884	Cell division ATP-binding protein ftsE
BH372_RS20155	COG2177	Part of the ABC transporter FtsEX involved in
BH372_RS20160	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BH372_RS20170	COG1194	a g-specific adenine glycosylase
BH372_RS20180	COG2226	methyltransferase
BH372_RS20190	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH372_RS20195	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH372_RS20210	COG1024	Enoyl-CoA hydratase
BH372_RS20230	COG1024	Enoyl-CoA hydratase
BH372_RS20235	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BH372_RS20250	COG0753	catalase activity
BH372_RS20255	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BH372_RS20260	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BH372_RS20270	COG2175	clavaminate synthase activity
BH372_RS20275	COG1473	amidohydrolase
BH372_RS20280	COG4608	Belongs to the ABC transporter superfamily
BH372_RS20285	COG0444	Belongs to the ABC transporter superfamily
BH372_RS20300	COG0747	negative chemotaxis
BH372_RS20305	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BH372_RS20320	COG5002	protein histidine kinase activity
BH372_RS20320	COG3850	Histidine kinase
BH372_RS20340	COG0436	Aminotransferase
BH372_RS20345	COG1278	Cold shock
BH372_RS20495	COG1596	polysaccharide export
BH372_RS20495	COG1555	photosystem II stabilization
BH372_RS20590	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BH372_RS20665	COG0463	Glycosyl transferase, family 2
BH372_RS20740	COG3842	ATPase activity
BH372_RS20855	COG4172	Belongs to the ABC transporter superfamily
BH372_RS20905	COG0537	adenosine 5'-monophosphoramidase activity
BH372_RS21035	COG0658	competence protein
BH372_RS21035	COG2333	competence protein COMEC