locus-tag	class	description
B1917_RS00005	COG0445	tRNA wobble uridine modification
B1917_RS00010	COG0357	Ribosomal RNA small subunit methyltransferase G
B1917_RS00015	COG1192	Involved in chromosome partitioning
B1917_RS00025	COG1475	DNA binding
B1917_RS00030	COG0252	asparaginase activity
B1917_RS00055	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
B1917_RS00065	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
B1917_RS00075	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
B1917_RS00080	COG0081	regulation of translation
B1917_RS00085	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
B1917_RS00090	COG0222	ribosome binding
B1917_RS00095	COG0085	RNA polymerase activity
B1917_RS00100	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
B1917_RS00140	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B1917_RS00165	COG1024	Enoyl-CoA hydratase
B1917_RS00185	COG0752	glycyl-tRNA synthetase alpha subunit
B1917_RS00190	COG0751	glycine-tRNA ligase activity
B1917_RS00195	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
B1917_RS00200	COG0204	Acyl-transferase
B1917_RS00215	COG0242	peptide deformylase activity
B1917_RS00250	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
B1917_RS00255	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B1917_RS00260	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B1917_RS00260	COG2813	Specifically methylates the guanine in position
B1917_RS00270	COG2223	nitrite transmembrane transporter activity
B1917_RS00280	COG1794	racemase activity, acting on amino acids and derivatives
B1917_RS00285	COG1126	abc transporter atp-binding protein
B1917_RS00290	COG0765	amino acid transport
B1917_RS00295	COG0765	amino acid transport
B1917_RS00300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B1917_RS00355	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B1917_RS00380	COG0326	Molecular chaperone. Has ATPase activity
B1917_RS00385	COG0625	glutathione transferase activity
B1917_RS00400	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B1917_RS00405	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
B1917_RS00435	COG0438	transferase activity, transferring glycosyl groups
B1917_RS00440	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
B1917_RS00445	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
B1917_RS00475	COG0859	PFAM glycosyl transferase family 9
B1917_RS00490	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
B1917_RS00500	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
B1917_RS00505	COG1127	ABC transporter
B1917_RS00530	COG1686	Belongs to the peptidase S11 family
B1917_RS00540	COG2921	Belongs to the UPF0250 family
B1917_RS00545	COG0321	lipoyl(octanoyl) transferase activity
B1917_RS00550	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
B1917_RS00585	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
B1917_RS00595	COG0018	arginyl-trna synthetase
B1917_RS00615	COG0395	ABC-type sugar transport system, permease component
B1917_RS00620	COG1175	transmembrane transport
B1917_RS00625	COG1653	transport
B1917_RS00630	COG3842	ATPase activity
B1917_RS00635	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
B1917_RS00645	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
B1917_RS00665	COG1609	Transcriptional regulator
B1917_RS00675	COG0154	amidase activity
B1917_RS00680	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B1917_RS00690	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
B1917_RS00700	COG0583	DNA-binding transcription factor activity
B1917_RS00715	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
B1917_RS00720	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B1917_RS00735	COG1802	Transcriptional regulator
B1917_RS00750	COG1024	Enoyl-CoA hydratase
B1917_RS00765	COG3181	Tripartite tricarboxylate transporter family receptor
B1917_RS00780	COG1984	allophanate hydrolase subunit 2
B1917_RS00785	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
B1917_RS00795	COG0583	DNA-binding transcription factor activity
B1917_RS00800	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B1917_RS00810	COG5002	protein histidine kinase activity
B1917_RS00820	COG5002	protein histidine kinase activity
B1917_RS00825	COG0745	RESPONSE REGULATOR receiver
B1917_RS00830	COG2226	methyltransferase
B1917_RS00845	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
B1917_RS00865	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
B1917_RS00875	COG0513	Belongs to the DEAD box helicase family
B1917_RS00880	COG1280	lysine exporter protein (LysE YggA)
B1917_RS00885	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
B1917_RS00920	COG1054	Belongs to the UPF0176 family
B1917_RS00925	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B1917_RS00925	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B1917_RS00935	COG0489	protein tyrosine kinase activity
B1917_RS00950	COG0717	Belongs to the dCTP deaminase family
B1917_RS00980	COG2081	HI0933 family
B1917_RS00990	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
B1917_RS01000	COG0404	The glycine cleavage system catalyzes the degradation of glycine
B1917_RS01005	COG0509	glycine decarboxylation via glycine cleavage system
B1917_RS01010	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B1917_RS01010	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B1917_RS01050	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B1917_RS01065	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
B1917_RS01075	COG1414	Transcriptional regulator
B1917_RS01080	COG1028	Short-chain dehydrogenase reductase Sdr
B1917_RS01085	COG2031	fatty acid transporter
B1917_RS01090	COG1250	3-hydroxyacyl-CoA dehydrogenase
B1917_RS01100	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
B1917_RS01105	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
B1917_RS01115	COG4257	antibiotic catabolic process
B1917_RS01135	COG1012	belongs to the aldehyde dehydrogenase family
B1917_RS01140	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
B1917_RS01145	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B1917_RS01170	COG1028	Short-chain dehydrogenase reductase Sdr
B1917_RS01180	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B1917_RS01190	COG2188	Transcriptional regulator
B1917_RS01195	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
B1917_RS01220	COG0617	tRNA 3'-terminal CCA addition
B1917_RS01235	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
B1917_RS01240	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
B1917_RS01245	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
B1917_RS01250	COG0586	Pfam SNARE associated Golgi protein
B1917_RS01255	COG0860	N-Acetylmuramoyl-L-alanine amidase
B1917_RS01260	COG0802	atpase or kinase
B1917_RS01265	COG0114	fumarate hydratase activity
B1917_RS01275	COG3181	Tripartite tricarboxylate transporter family receptor
B1917_RS01285	COG0405	Gamma-glutamyltransferase
B1917_RS01290	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B1917_RS01300	COG1960	acyl-CoA dehydrogenase activity
B1917_RS01325	COG1294	oxidase, subunit
B1917_RS01335	COG4988	ABC transporter
B1917_RS01340	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
B1917_RS01345	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
B1917_RS01360	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
B1917_RS01385	COG2969	positive regulation of protein catabolic process
B1917_RS01390	COG0625	glutathione transferase activity
B1917_RS01395	COG2857	Cytochrome c1
B1917_RS01400	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
B1917_RS01405	COG0723	plastoquinol--plastocyanin reductase activity
B1917_RS01410	COG1970	mechanosensitive ion channel activity
B1917_RS01415	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
B1917_RS01430	COG2808	Putative FMN-binding domain
B1917_RS01435	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B1917_RS01440	COG0747	negative chemotaxis
B1917_RS01445	COG0657	acetylesterase activity
B1917_RS01455	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B1917_RS01460	COG2207	Transcriptional regulator
B1917_RS01465	COG0129	dihydroxy-acid dehydratase activity
B1917_RS01470	COG2814	Major facilitator Superfamily
B1917_RS01475	COG0583	DNA-binding transcription factor activity
B1917_RS01485	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
B1917_RS01555	COG1024	Enoyl-CoA hydratase
B1917_RS01560	COG1960	acyl-CoA dehydrogenase activity
B1917_RS01585	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
B1917_RS01590	COG0352	thiamine-phosphate diphosphorylase activity
B1917_RS01605	COG1678	Uncharacterized ACR, COG1678
B1917_RS01610	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
B1917_RS01615	COG0540	Belongs to the ATCase OTCase family
B1917_RS01630	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
B1917_RS01640	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B1917_RS01675	COG1234	tRNA 3'-trailer cleavage
B1917_RS01720	COG1683	Conserved Protein
B1917_RS01725	COG1120	ATPase activity
B1917_RS01730	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B1917_RS01735	COG4558	Periplasmic binding protein
B1917_RS01740	COG3720	iron ion transport
B1917_RS01750	COG3712	iron ion homeostasis
B1917_RS01755	COG1595	DNA-templated transcription, initiation
B1917_RS01790	COG1802	Transcriptional regulator
B1917_RS01800	COG3069	C4-dicarboxylate transmembrane transporter activity
B1917_RS01810	COG1012	belongs to the aldehyde dehydrogenase family
B1917_RS01845	COG2860	membrane
B1917_RS01850	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
B1917_RS01855	COG0708	Exodeoxyribonuclease III
B1917_RS01860	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
B1917_RS01865	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
B1917_RS01870	COG0154	amidase activity
B1917_RS01875	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
B1917_RS01880	COG1077	Cell shape determining protein MreB Mrl
B1917_RS01885	COG1792	Involved in formation and maintenance of cell shape
B1917_RS01895	COG0768	penicillin binding
B1917_RS01900	COG0772	Belongs to the SEDS family
B1917_RS01905	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
B1917_RS01910	COG0471	metal ion transport
B1917_RS01915	COG1309	transcriptional regulator
B1917_RS01925	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
B1917_RS01940	COG2823	Periplasmic or secreted lipoprotein
B1917_RS01945	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
B1917_RS01960	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B1917_RS01980	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B1917_RS01990	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B1917_RS02015	COG0492	ferredoxin-NADP+ reductase activity
B1917_RS02025	COG3181	Tripartite tricarboxylate transporter family receptor
B1917_RS02030	COG1024	Enoyl-CoA hydratase
B1917_RS02030	COG1250	3-hydroxyacyl-CoA dehydrogenase
B1917_RS02035	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B1917_RS02040	COG0028	Belongs to the TPP enzyme family
B1917_RS02065	COG3181	Tripartite tricarboxylate transporter family receptor
B1917_RS02075	COG0697	spore germination
B1917_RS02100	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
B1917_RS02105	COG0463	Glycosyl transferase, family 2
B1917_RS02120	COG0786	glutamate:sodium symporter activity
B1917_RS02130	COG2031	fatty acid transporter
B1917_RS02145	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B1917_RS02150	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B1917_RS02170	COG3181	Tripartite tricarboxylate transporter family receptor
B1917_RS02180	COG0277	FAD linked oxidase domain protein
B1917_RS02185	COG1960	acyl-CoA dehydrogenase activity
B1917_RS02190	COG1960	acyl-CoA dehydrogenase activity
B1917_RS02200	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B1917_RS02215	COG2072	flavoprotein involved in K transport
B1917_RS02220	COG0604	alcohol dehydrogenase
B1917_RS02235	COG1024	Enoyl-CoA hydratase
B1917_RS02255	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B1917_RS02260	COG1522	sequence-specific DNA binding
B1917_RS02265	COG0183	Belongs to the thiolase family
B1917_RS02275	COG1960	acyl-CoA dehydrogenase activity
B1917_RS02320	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
B1917_RS02325	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
B1917_RS02330	COG2890	protein-(glutamine-N5) methyltransferase activity
B1917_RS02335	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
B1917_RS02345	COG3181	Tripartite tricarboxylate transporter family receptor
B1917_RS02385	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
B1917_RS02390	COG1660	Displays ATPase and GTPase activities
B1917_RS02400	COG2010	Cytochrome c
B1917_RS02400	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B1917_RS02405	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
B1917_RS02415	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
B1917_RS02420	COG1137	ATPase activity
B1917_RS02435	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
B1917_RS02445	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
B1917_RS02475	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
B1917_RS02480	COG3568	Endonuclease Exonuclease Phosphatase
B1917_RS02485	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B1917_RS02515	COG0154	amidase activity
B1917_RS02525	COG1414	Transcriptional regulator
B1917_RS02540	COG1024	Enoyl-CoA hydratase
B1917_RS02540	COG1250	3-hydroxyacyl-CoA dehydrogenase
B1917_RS02550	COG2132	Multicopper oxidase
B1917_RS02580	COG1250	3-hydroxyacyl-CoA dehydrogenase
B1917_RS02605	COG1024	Enoyl-CoA hydratase
B1917_RS02610	COG1024	Enoyl-CoA hydratase
B1917_RS02615	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
B1917_RS02635	COG0601	transmembrane transport
B1917_RS02640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B1917_RS02660	COG2195	Cleaves the N-terminal amino acid of tripeptides
B1917_RS02670	COG0210	DNA helicase
B1917_RS02675	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
B1917_RS02680	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
B1917_RS02690	COG0355	proton-transporting ATP synthase activity, rotational mechanism
B1917_RS02695	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
B1917_RS02700	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
B1917_RS02705	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
B1917_RS02710	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
B1917_RS02715	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
B1917_RS02725	COG0356	it plays a direct role in the translocation of protons across the membrane
B1917_RS02750	COG1024	Enoyl-CoA hydratase
B1917_RS02755	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B1917_RS02760	COG3634	alkyl hydroperoxide reductase activity
B1917_RS02770	COG0037	tRNA processing
B1917_RS02780	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B1917_RS02785	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
B1917_RS02790	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B1917_RS02795	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
B1917_RS02800	COG2967	ApaG domain
B1917_RS02805	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
B1917_RS02810	COG0546	phosphoglycolate phosphatase activity
B1917_RS02820	COG0512	Glutamine amidotransferase of anthranilate synthase
B1917_RS02825	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
B1917_RS02830	COG0134	indole-3-glycerol-phosphate synthase activity
B1917_RS02855	COG1960	acyl-CoA dehydrogenase activity
B1917_RS02860	COG0583	DNA-binding transcription factor activity
B1917_RS02875	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B1917_RS02880	COG0259	pyridoxamine-phosphate oxidase activity
B1917_RS02890	COG2814	Major facilitator Superfamily
B1917_RS02895	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
B1917_RS02900	COG2188	Transcriptional regulator
B1917_RS02905	COG0318	PFAM AMP-dependent synthetase and ligase
B1917_RS02925	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B1917_RS02935	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
B1917_RS02950	COG1215	transferase activity, transferring glycosyl groups
B1917_RS02960	COG0601	transmembrane transport
B1917_RS02970	COG0488	(ABC) transporter
B1917_RS02990	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
B1917_RS02995	COG2894	cell division
B1917_RS03000	COG0850	regulation of cytokinetic process
B1917_RS03005	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
B1917_RS03010	COG1271	oxidase subunit
B1917_RS03045	COG2979	Protein of unknown function (DUF533)
B1917_RS03065	COG1388	LysM domain
B1917_RS03065	COG0741	lytic transglycosylase activity
B1917_RS03070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B1917_RS03075	COG2226	methyltransferase
B1917_RS03080	COG0328	RNA-DNA hybrid ribonuclease activity
B1917_RS03125	COG2030	dehydratase
B1917_RS03130	COG0183	Belongs to the thiolase family
B1917_RS03175	COG1960	acyl-CoA dehydrogenase activity
B1917_RS03190	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B1917_RS03195	COG1028	Short-chain dehydrogenase reductase Sdr
B1917_RS03210	COG2718	Belongs to the UPF0229 family
B1917_RS03215	COG2719	SpoVR family
B1917_RS03240	COG2188	Transcriptional regulator
B1917_RS03255	COG0633	Ferredoxin
B1917_RS03265	COG0829	nickel cation binding
B1917_RS03270	COG0831	urea catabolic process
B1917_RS03280	COG0832	Belongs to the urease beta subunit family
B1917_RS03285	COG0804	urea catabolic process
B1917_RS03295	COG0830	nickel cation binding
B1917_RS03300	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
B1917_RS03320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B1917_RS03325	COG0601	transmembrane transport
B1917_RS03330	COG0747	negative chemotaxis
B1917_RS03340	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B1917_RS03345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B1917_RS03355	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
B1917_RS03365	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
B1917_RS03370	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B1917_RS03375	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
B1917_RS03390	COG0438	transferase activity, transferring glycosyl groups
B1917_RS03405	COG0438	transferase activity, transferring glycosyl groups
B1917_RS03410	COG0438	transferase activity, transferring glycosyl groups
B1917_RS03415	COG0166	Belongs to the GPI family
B1917_RS03430	COG0277	FAD linked oxidase domain protein
B1917_RS03435	COG0745	RESPONSE REGULATOR receiver
B1917_RS03440	COG0642	Histidine kinase
B1917_RS03445	COG1368	sulfuric ester hydrolase activity
B1917_RS03455	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
B1917_RS03480	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
B1917_RS03490	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
B1917_RS03495	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
B1917_RS03505	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
B1917_RS03510	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
B1917_RS03515	COG0193	aminoacyl-tRNA hydrolase activity
B1917_RS03525	COG0012	GTP binding
B1917_RS03530	COG0582	viral genome integration into host DNA
B1917_RS03550	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
B1917_RS03595	COG0745	RESPONSE REGULATOR receiver
B1917_RS03610	COG1309	transcriptional regulator
B1917_RS03635	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B1917_RS03645	COG0405	Gamma-glutamyltransferase
B1917_RS03660	COG1280	lysine exporter protein (LysE YggA)
B1917_RS03720	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
B1917_RS03725	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B1917_RS03735	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
B1917_RS03740	COG0513	Belongs to the DEAD box helicase family
B1917_RS03750	COG0617	tRNA 3'-terminal CCA addition
B1917_RS03765	COG0477	Major facilitator Superfamily
B1917_RS03775	COG0583	DNA-binding transcription factor activity
B1917_RS03790	COG1950	PFAM Membrane protein of
B1917_RS03795	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
B1917_RS03810	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
B1917_RS03820	COG1560	Kdo2-lipid A biosynthetic process
B1917_RS03825	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
B1917_RS03835	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
B1917_RS03845	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
B1917_RS03855	COG0803	Belongs to the bacterial solute-binding protein 9 family
B1917_RS03875	COG0735	belongs to the Fur family
B1917_RS03880	COG0523	cobalamin synthesis protein
B1917_RS03890	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
B1917_RS03895	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
B1917_RS03905	COG2096	Adenosyltransferase
B1917_RS03920	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
B1917_RS03925	COG2084	Dehydrogenase
B1917_RS03970	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
B1917_RS03975	COG0129	dihydroxy-acid dehydratase activity
B1917_RS03980	COG4654	Cytochrome c, class I
B1917_RS03985	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B1917_RS04035	COG1473	amidohydrolase
B1917_RS04040	COG0418	dihydroorotase activity
B1917_RS04045	COG0488	(ABC) transporter
B1917_RS04050	COG2001	Belongs to the MraZ family
B1917_RS04055	COG0275	rRNA processing
B1917_RS04060	COG3116	cell division
B1917_RS04070	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
B1917_RS04075	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B1917_RS04080	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
B1917_RS04090	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
B1917_RS04095	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
B1917_RS04100	COG1181	Belongs to the D-alanine--D-alanine ligase family
B1917_RS04105	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
B1917_RS04115	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
B1917_RS04120	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
B1917_RS04130	COG0739	heme binding
B1917_RS04135	COG0653	protein targeting
B1917_RS04155	COG1028	Short-chain dehydrogenase reductase Sdr
B1917_RS04160	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B1917_RS04165	COG1522	sequence-specific DNA binding
B1917_RS04185	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
B1917_RS04195	COG0557	exoribonuclease II activity
B1917_RS04200	COG3150	esterase
B1917_RS04205	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
B1917_RS04210	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B1917_RS04215	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
B1917_RS04220	COG0511	ligase activity, forming carbon-carbon bonds
B1917_RS04225	COG0439	Biotin carboxylase
B1917_RS04230	COG2264	protein methyltransferase activity
B1917_RS04240	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B1917_RS04265	COG1696	Membrane protein involved in D-alanine export
B1917_RS04270	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B1917_RS04305	COG1522	sequence-specific DNA binding
B1917_RS04320	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
B1917_RS04325	COG0045	succinate-CoA ligase (ADP-forming) activity
B1917_RS04325	COG1042	CoA-binding domain protein
B1917_RS04325	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B1917_RS04335	COG1802	Transcriptional regulator
B1917_RS04340	COG3069	C4-dicarboxylate transmembrane transporter activity
B1917_RS04345	COG0513	Belongs to the DEAD box helicase family
B1917_RS04350	COG0346	lactoylglutathione lyase activity
B1917_RS04355	COG1335	isochorismatase
B1917_RS04360	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B1917_RS04365	COG1116	anion transmembrane transporter activity
B1917_RS04380	COG3028	Belongs to the UPF0307 family
B1917_RS04385	COG0312	modulator of DNA gyrase
B1917_RS04390	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
B1917_RS04395	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
B1917_RS04400	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
B1917_RS04405	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
B1917_RS04415	COG0316	Belongs to the HesB IscA family
B1917_RS04420	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
B1917_RS04435	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
B1917_RS04445	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
B1917_RS04450	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
B1917_RS04465	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B1917_RS04465	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B1917_RS04495	COG0583	DNA-binding transcription factor activity
B1917_RS04500	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B1917_RS04535	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
B1917_RS04545	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B1917_RS04550	COG1845	cytochrome c oxidase, subunit III
B1917_RS04555	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
B1917_RS04560	COG0640	Transcriptional regulator
B1917_RS04580	COG3220	belongs to the UPF0276 family
B1917_RS04625	COG1666	GTP binding
B1917_RS04660	COG0312	modulator of DNA gyrase
B1917_RS04665	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
B1917_RS04670	COG3210	domain, Protein
B1917_RS04670	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
B1917_RS04670	COG3210	domain, Protein
B1917_RS04670	COG3064	Membrane
B1917_RS04670	COG3064	Membrane
B1917_RS04670	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
B1917_RS04675	COG0277	FAD linked oxidase domain protein
B1917_RS04680	COG0277	FAD linked oxidase domain protein
B1917_RS04685	COG0277	FAD linked oxidase domain protein
B1917_RS04690	COG0247	lactate metabolic process
B1917_RS04695	COG2819	hydrolase of the alpha beta superfamily
B1917_RS04730	COG0583	DNA-binding transcription factor activity
B1917_RS04735	COG0482	sulfurtransferase activity
B1917_RS04740	COG0730	response to heat
B1917_RS04745	COG0625	glutathione transferase activity
B1917_RS04750	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
B1917_RS04755	COG3909	cytochrome
B1917_RS04795	COG0154	amidase activity
B1917_RS04800	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B1917_RS04805	COG1024	Enoyl-CoA hydratase
B1917_RS04820	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B1917_RS04835	COG1028	Short-chain dehydrogenase reductase Sdr
B1917_RS04840	COG1414	Transcriptional regulator
B1917_RS04850	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B1917_RS04855	COG0251	oxidation-reduction process
B1917_RS04860	COG0559	Belongs to the binding-protein-dependent transport system permease family
B1917_RS04880	COG1902	pentaerythritol trinitrate reductase activity
B1917_RS04895	COG0583	DNA-binding transcription factor activity
B1917_RS04905	COG0590	tRNA wobble adenosine to inosine editing
B1917_RS04910	COG2807	transmembrane transport
B1917_RS04930	COG0154	amidase activity
B1917_RS04935	COG0307	riboflavin synthase, alpha
B1917_RS04940	COG3181	Tripartite tricarboxylate transporter family receptor
B1917_RS04945	COG1522	sequence-specific DNA binding
B1917_RS04955	COG0318	PFAM AMP-dependent synthetase and ligase
B1917_RS04965	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B1917_RS04985	COG1063	alcohol dehydrogenase
B1917_RS05010	COG1418	mRNA catabolic process
B1917_RS05015	COG1448	Aminotransferase
B1917_RS05020	COG0583	DNA-binding transcription factor activity
B1917_RS05030	COG0477	Major facilitator Superfamily
B1917_RS05035	COG1028	Short-chain dehydrogenase reductase Sdr
B1917_RS05050	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
B1917_RS05055	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
B1917_RS05060	COG0583	DNA-binding transcription factor activity
B1917_RS05100	COG1028	Short-chain dehydrogenase reductase Sdr
B1917_RS05105	COG1309	transcriptional regulator
B1917_RS05115	COG2982	Protein involved in outer membrane biogenesis
B1917_RS05120	COG2818	Glycosylase
B1917_RS05140	COG1653	transport
B1917_RS05150	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B1917_RS05155	COG3842	ATPase activity
B1917_RS05160	COG0395	ABC-type sugar transport system, permease component
B1917_RS05165	COG1175	transmembrane transport
B1917_RS05190	COG3181	Tripartite tricarboxylate transporter family receptor
B1917_RS05195	COG2186	Transcriptional regulator
B1917_RS05220	COG1454	alcohol dehydrogenase
B1917_RS05240	COG2011	ABC-type metal ion transport system permease component
B1917_RS05245	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
B1917_RS05250	COG1501	Belongs to the glycosyl hydrolase 31 family
B1917_RS05270	COG0318	PFAM AMP-dependent synthetase and ligase
B1917_RS05275	COG1473	amidohydrolase
B1917_RS05285	COG2855	membrane
B1917_RS05295	COG2239	Acts as a magnesium transporter
B1917_RS05315	COG3181	Tripartite tricarboxylate transporter family receptor
B1917_RS05325	COG1722	exodeoxyribonuclease VII activity
B1917_RS05330	COG0142	geranyltranstransferase activity
B1917_RS05335	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
B1917_RS05340	COG1469	GTP cyclohydrolase I activity
B1917_RS05345	COG0360	Binds together with S18 to 16S ribosomal RNA
B1917_RS05350	COG2965	DNA replication, synthesis of RNA primer
B1917_RS05355	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
B1917_RS05360	COG0359	binds to the 23S rRNA
B1917_RS05370	COG0305	Participates in initiation and elongation during chromosome replication
B1917_RS05380	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
B1917_RS05385	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
B1917_RS05390	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
B1917_RS05395	COG3737	Protein of unknown function (DUF498/DUF598)
B1917_RS05400	COG0436	Aminotransferase
B1917_RS05425	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
B1917_RS05455	COG0268	Binds directly to 16S ribosomal RNA
B1917_RS05465	COG0728	peptidoglycan biosynthetic process
B1917_RS05475	COG0563	adenylate kinase activity
B1917_RS05480	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
B1917_RS05485	COG2835	tetraacyldisaccharide 4'-kinase activity
B1917_RS05490	COG1663	tetraacyldisaccharide 4'-kinase activity
B1917_RS05495	COG0848	biopolymer transport protein
B1917_RS05500	COG0811	peptide transport
B1917_RS05510	COG1570	exodeoxyribonuclease VII activity
B1917_RS05515	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
B1917_RS05520	COG0038	chloride channel
B1917_RS05525	COG0183	Belongs to the thiolase family
B1917_RS05535	COG1278	Cold shock
B1917_RS05540	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
B1917_RS05550	COG4953	penicillin-binding protein 1C
B1917_RS05555	COG0542	response to heat
B1917_RS05560	COG2995	paraquat-inducible protein a
B1917_RS05565	COG3008	intermembrane lipid transfer
B1917_RS05565	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
B1917_RS05575	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
B1917_RS05575	COG0506	proline dehydrogenase activity
B1917_RS05575	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
B1917_RS05610	COG2271	Major facilitator Superfamily
B1917_RS05615	COG1309	transcriptional regulator
B1917_RS05625	COG3468	outer membrane autotransporter barrel domain protein
B1917_RS05655	COG0477	Major facilitator Superfamily
B1917_RS05665	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B1917_RS05670	COG1845	cytochrome c oxidase, subunit III
B1917_RS05675	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
B1917_RS05685	COG1028	Short-chain dehydrogenase reductase Sdr
B1917_RS05705	COG0789	Transcriptional regulator
B1917_RS05730	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
B1917_RS05735	COG0697	spore germination
B1917_RS05745	COG0678	peroxiredoxin activity
B1917_RS05755	COG0412	Dienelactone hydrolase
B1917_RS05765	COG0315	cyclic pyranopterin monophosphate synthase activity
B1917_RS05780	COG0521	Mo-molybdopterin cofactor biosynthetic process
B1917_RS05785	COG0303	'Molybdopterin
B1917_RS05790	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
B1917_RS05810	COG0165	Argininosuccinate lyase
B1917_RS05815	COG0668	transmembrane transport
B1917_RS05860	COG0747	negative chemotaxis
B1917_RS05865	COG0601	transmembrane transport
B1917_RS05870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B1917_RS05875	COG1162	GTPase activity
B1917_RS05880	COG0501	Belongs to the peptidase M48B family
B1917_RS05885	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
B1917_RS05895	COG3327	negative regulation of DNA-templated transcription, initiation
B1917_RS05900	COG3396	Phenylacetate-CoA oxygenase
B1917_RS05905	COG3460	Phenylacetate-CoA oxygenase
B1917_RS05910	COG3396	Phenylacetate-CoA oxygenase
B1917_RS05915	COG2151	metal-sulfur cluster biosynthetic enzyme
B1917_RS05920	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B1917_RS05930	COG1012	belongs to the aldehyde dehydrogenase family
B1917_RS05935	COG1024	Enoyl-CoA hydratase
B1917_RS05940	COG2050	protein possibly involved in aromatic compounds catabolism
B1917_RS05950	COG3539	Fimbrial protein
B1917_RS05965	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B1917_RS05970	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
B1917_RS05970	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
B1917_RS05975	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
B1917_RS05980	COG0047	phosphoribosylformylglycinamidine synthase activity
B1917_RS05980	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
B1917_RS05985	COG3064	Membrane
B1917_RS05985	COG3210	domain, Protein
B1917_RS05985	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
B1917_RS06010	COG0235	Class ii aldolase
B1917_RS06015	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
B1917_RS06020	COG0720	synthase
B1917_RS06025	COG0602	queuosine metabolic process
B1917_RS06050	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B1917_RS06085	COG3181	Tripartite tricarboxylate transporter family receptor
B1917_RS06115	COG3842	ATPase activity
B1917_RS06125	COG0395	ABC-type sugar transport system, permease component
B1917_RS06155	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B1917_RS06160	COG0420	3'-5' exonuclease activity
B1917_RS06185	COG2197	response regulator
B1917_RS06210	COG0518	GMP synthase (glutamine-hydrolyzing) activity
B1917_RS06210	COG0519	Catalyzes the synthesis of GMP from XMP
B1917_RS06220	COG3550	peptidyl-serine autophosphorylation
B1917_RS06230	COG0477	Major facilitator Superfamily
B1917_RS06245	COG1228	amidohydrolase
B1917_RS06255	COG1116	anion transmembrane transporter activity
B1917_RS06260	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B1917_RS06295	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
B1917_RS06310	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
B1917_RS06340	COG2814	Major facilitator Superfamily
B1917_RS06355	COG1280	lysine exporter protein (LysE YggA)
B1917_RS06370	COG0747	negative chemotaxis
B1917_RS06375	COG0601	transmembrane transport
B1917_RS06380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B1917_RS06385	COG4172	Belongs to the ABC transporter superfamily
B1917_RS06390	COG1609	Transcriptional regulator
B1917_RS06415	COG0586	Pfam SNARE associated Golgi protein
B1917_RS06425	COG0500	methyltransferase
B1917_RS06440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B1917_RS06450	COG0756	dUTP diphosphatase activity
B1917_RS06460	COG0291	Belongs to the bacterial ribosomal protein bL35 family
B1917_RS06465	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
B1917_RS06470	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
B1917_RS06475	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B1917_RS06475	COG0072	phenylalanine-tRNA ligase activity
B1917_RS06480	COG0776	regulation of translation
B1917_RS06550	COG0540	Belongs to the ATCase OTCase family
B1917_RS06555	COG2974	May be involved in recombination
B1917_RS06565	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B1917_RS06570	COG0583	DNA-binding transcription factor activity
B1917_RS06590	COG1028	Short-chain dehydrogenase reductase Sdr
B1917_RS06605	COG3842	ATPase activity
B1917_RS06610	COG1250	3-hydroxyacyl-CoA dehydrogenase
B1917_RS06610	COG1024	Enoyl-CoA hydratase
B1917_RS06630	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
B1917_RS06635	COG2137	regulation of response to DNA damage stimulus
B1917_RS06645	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
B1917_RS06655	COG0045	succinate-CoA ligase (ADP-forming) activity
B1917_RS06660	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
B1917_RS06665	COG0861	Integral membrane protein TerC family
B1917_RS06670	COG0861	Integral membrane protein TerC family
B1917_RS06680	COG0181	hydroxymethylbilane synthase activity
B1917_RS06740	COG4964	Belongs to the GSP D family
B1917_RS06770	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
B1917_RS06780	COG0583	DNA-binding transcription factor activity
B1917_RS06790	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B1917_RS06795	COG4311	Sarcosine oxidase, delta subunit
B1917_RS06800	COG0446	pyridine nucleotide-disulphide oxidoreductase
B1917_RS06800	COG0404	The glycine cleavage system catalyzes the degradation of glycine
B1917_RS06835	COG0812	UDP-N-acetylmuramate dehydrogenase activity
B1917_RS06840	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
B1917_RS06845	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B1917_RS06850	COG0735	belongs to the Fur family
B1917_RS06855	COG0497	DNA recombination
B1917_RS06860	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
B1917_RS06865	COG1420	regulation of RNA biosynthetic process
B1917_RS06870	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
B1917_RS06880	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
B1917_RS06890	COG0443	Heat shock 70 kDa protein
B1917_RS06900	COG0612	Peptidase, M16
B1917_RS06920	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B1917_RS06965	COG0745	RESPONSE REGULATOR receiver
B1917_RS06970	COG2205	protein histidine kinase activity
B1917_RS06975	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
B1917_RS06980	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
B1917_RS06985	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
B1917_RS06995	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B1917_RS07015	COG1193	negative regulation of DNA recombination
B1917_RS07020	COG0492	ferredoxin-NADP+ reductase activity
B1917_RS07025	COG1674	ftsk spoiiie
B1917_RS07030	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
B1917_RS07035	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
B1917_RS07040	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
B1917_RS07065	COG3706	GGDEF domain
B1917_RS07085	COG2814	Major facilitator Superfamily
B1917_RS07115	COG3486	L-lysine 6-monooxygenase (NADPH) activity
B1917_RS07130	COG1028	Short-chain dehydrogenase reductase Sdr
B1917_RS07140	COG3022	response to hydroperoxide
B1917_RS07150	COG1289	transmembrane transporter activity
B1917_RS07170	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B1917_RS07180	COG2197	response regulator
B1917_RS07185	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
B1917_RS07190	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
B1917_RS07195	COG0189	ligase activity
B1917_RS07205	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B1917_RS07210	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B1917_RS07220	COG2423	ornithine cyclodeaminase activity
B1917_RS07230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B1917_RS07235	COG0765	amino acid transport
B1917_RS07240	COG0765	amino acid transport
B1917_RS07245	COG1126	abc transporter atp-binding protein
B1917_RS07300	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
B1917_RS07310	COG2944	sequence-specific DNA binding
B1917_RS07315	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
B1917_RS07320	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
B1917_RS07325	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
B1917_RS07330	COG0009	L-threonylcarbamoyladenylate synthase
B1917_RS07335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B1917_RS07340	COG1414	Transcriptional regulator
B1917_RS07355	COG0765	amino acid transport
B1917_RS07360	COG1126	abc transporter atp-binding protein
B1917_RS07365	COG0028	Belongs to the TPP enzyme family
B1917_RS07380	COG0028	Belongs to the TPP enzyme family
B1917_RS07385	COG0583	DNA-binding transcription factor activity
B1917_RS07390	COG4974	Belongs to the 'phage' integrase family
B1917_RS07395	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
B1917_RS07400	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
B1917_RS07415	COG1686	Belongs to the peptidase S11 family
B1917_RS07425	COG2814	Major facilitator Superfamily
B1917_RS07435	COG1074	ATP-dependent DNA helicase activity
B1917_RS07440	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
B1917_RS07445	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
B1917_RS07450	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
B1917_RS07470	COG2321	neutral zinc metallopeptidase
B1917_RS07475	COG0009	L-threonylcarbamoyladenylate synthase
B1917_RS07515	COG3360	Dodecin
B1917_RS07520	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
B1917_RS07525	COG2850	peptidyl-arginine hydroxylation
B1917_RS07530	COG3539	Fimbrial protein
B1917_RS07535	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
B1917_RS07540	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B1917_RS07545	COG1994	Peptidase M50
B1917_RS07555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B1917_RS07560	COG0765	amino acid transport
B1917_RS07565	COG1126	abc transporter atp-binding protein
B1917_RS07570	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B1917_RS07575	COG1758	RNA polymerase activity
B1917_RS07580	COG0194	GDP metabolic process
B1917_RS07585	COG3258	Cytochrome c
B1917_RS07590	COG2863	cytochrome
B1917_RS07595	COG1028	Short-chain dehydrogenase reductase Sdr
B1917_RS07600	COG0791	NLP P60 protein
B1917_RS07605	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
B1917_RS07625	COG1561	YicC-like family, N-terminal region
B1917_RS07630	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
B1917_RS07650	COG2199	diguanylate cyclase activity
B1917_RS07650	COG2200	EAL domain
B1917_RS07655	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
B1917_RS07670	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B1917_RS07675	COG0174	glutamine synthetase
B1917_RS07685	COG2204	response regulator
B1917_RS07690	COG0583	DNA-binding transcription factor activity
B1917_RS07695	COG1741	Belongs to the pirin family
B1917_RS07700	COG1741	Belongs to the pirin family
B1917_RS07710	COG3842	ATPase activity
B1917_RS07715	COG1178	ABC-type Fe3 transport system permease component
B1917_RS07720	COG1840	ABC-type Fe3 transport system, periplasmic component
B1917_RS07730	COG0583	DNA-binding transcription factor activity
B1917_RS07740	COG0656	L-ascorbic acid biosynthetic process
B1917_RS07755	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
B1917_RS07760	COG0583	DNA-binding transcription factor activity
B1917_RS07775	COG0783	Belongs to the Dps family
B1917_RS07810	COG0438	transferase activity, transferring glycosyl groups
B1917_RS07825	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
B1917_RS07850	COG0300	oxidoreductase activity
B1917_RS07895	COG0861	Integral membrane protein TerC family
B1917_RS07900	COG1028	Short-chain dehydrogenase reductase Sdr
B1917_RS07920	COG0714	Associated with various cellular activities
B1917_RS07950	COG3119	arylsulfatase activity
B1917_RS07975	COG2197	response regulator
B1917_RS07985	COG2944	sequence-specific DNA binding
B1917_RS07990	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
B1917_RS07995	COG0625	glutathione transferase activity
B1917_RS08025	COG0179	Fumarylacetoacetate (FAA) hydrolase
B1917_RS08030	COG1028	Short-chain dehydrogenase reductase Sdr
B1917_RS08075	COG0431	NADPH-dependent FMN reductase
B1917_RS08105	COG1028	Short-chain dehydrogenase reductase Sdr
B1917_RS08110	COG0583	DNA-binding transcription factor activity
B1917_RS08125	COG3181	Tripartite tricarboxylate transporter family receptor
B1917_RS08130	COG2111	Na H antiporter
B1917_RS08130	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
B1917_RS08135	COG1006	Multisubunit Na H antiporter MnhC subunit
B1917_RS08140	COG0651	ATP synthesis coupled electron transport
B1917_RS08145	COG1863	multisubunit Na H antiporter MnhE subunit
B1917_RS08150	COG2212	antiporter activity
B1917_RS08175	COG0590	tRNA wobble adenosine to inosine editing
B1917_RS08180	COG1619	proteins homologs of microcin C7 resistance protein MccF
B1917_RS08185	COG1024	Enoyl-CoA hydratase
B1917_RS08200	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
B1917_RS08205	COG0488	(ABC) transporter
B1917_RS08240	COG1017	nitric oxide dioxygenase activity
B1917_RS08240	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B1917_RS08245	COG1959	2 iron, 2 sulfur cluster binding
B1917_RS08250	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B1917_RS08270	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
B1917_RS08275	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
B1917_RS08280	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
B1917_RS08285	COG0084	hydrolase, TatD family'
B1917_RS08300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B1917_RS08310	COG1126	abc transporter atp-binding protein
B1917_RS08315	COG0010	Belongs to the arginase family
B1917_RS08320	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
B1917_RS08325	COG1012	belongs to the aldehyde dehydrogenase family
B1917_RS08335	COG0028	Belongs to the TPP enzyme family
B1917_RS08345	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
B1917_RS08345	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
B1917_RS08355	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B1917_RS08370	COG3189	MarR family transcriptional regulator
B1917_RS08395	COG4336	lyase activity
B1917_RS08405	COG2205	protein histidine kinase activity
B1917_RS08405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B1917_RS08410	COG2197	response regulator
B1917_RS08415	COG3064	Membrane
B1917_RS08415	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
B1917_RS08415	COG3210	domain, Protein
B1917_RS08425	COG3121	Chaperone
B1917_RS08430	COG3188	usher protein
B1917_RS08435	COG3539	Fimbrial protein
B1917_RS08440	COG2831	hemolysin activation secretion protein
B1917_RS08455	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B1917_RS08480	COG0583	DNA-binding transcription factor activity
B1917_RS08505	COG0668	transmembrane transport
B1917_RS08525	COG0483	inositol monophosphate 1-phosphatase activity
B1917_RS08530	COG1253	flavin adenine dinucleotide binding
B1917_RS08535	COG1968	undecaprenyl-diphosphatase activity
B1917_RS08540	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B1917_RS08555	COG0215	cysteine-tRNA ligase activity
B1917_RS08565	COG0825	malonyl-CoA metabolic process
B1917_RS08575	COG0037	tRNA processing
B1917_RS08580	COG0527	aspartate kinase activity
B1917_RS08605	COG1250	3-hydroxyacyl-CoA dehydrogenase
B1917_RS08610	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
B1917_RS08610	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
B1917_RS08625	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B1917_RS08630	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
B1917_RS08635	COG1028	Short-chain dehydrogenase reductase Sdr
B1917_RS08645	COG0583	DNA-binding transcription factor activity
B1917_RS08675	COG3842	ATPase activity
B1917_RS08685	COG0446	pyridine nucleotide-disulphide oxidoreductase
B1917_RS08685	COG1902	pentaerythritol trinitrate reductase activity
B1917_RS08690	COG1414	Transcriptional regulator
B1917_RS08695	COG1832	CoA-binding protein
B1917_RS08705	COG0251	oxidation-reduction process
B1917_RS08730	COG1902	pentaerythritol trinitrate reductase activity
B1917_RS08740	COG1215	transferase activity, transferring glycosyl groups
B1917_RS08745	COG1649	PFAM Uncharacterised BCR, COG1649
B1917_RS08745	COG0726	polysaccharide deacetylase
B1917_RS08765	COG1846	Transcriptional regulator
B1917_RS08785	COG0166	Belongs to the GPI family
B1917_RS08790	COG1045	serine acetyltransferase
B1917_RS08800	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
B1917_RS08805	COG0483	inositol monophosphate 1-phosphatase activity
B1917_RS08810	COG1012	belongs to the aldehyde dehydrogenase family
B1917_RS08815	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
B1917_RS08830	COG0210	DNA helicase
B1917_RS08835	COG0598	Magnesium transport protein CorA
B1917_RS08845	COG0747	negative chemotaxis
B1917_RS08850	COG0601	transmembrane transport
B1917_RS08855	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B1917_RS08860	COG4172	Belongs to the ABC transporter superfamily
B1917_RS08865	COG1846	Transcriptional regulator
B1917_RS08915	COG4964	Belongs to the GSP D family
B1917_RS08955	COG2204	response regulator
B1917_RS08970	COG1595	DNA-templated transcription, initiation
B1917_RS08980	COG3474	cytochrome
B1917_RS08985	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
B1917_RS09000	COG3384	dioxygenase
B1917_RS09005	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
B1917_RS09030	COG2885	chlorophyll binding
B1917_RS09065	COG0697	spore germination
B1917_RS09070	COG0730	response to heat
B1917_RS09085	COG0583	DNA-binding transcription factor activity
B1917_RS09090	COG0427	acetyl-CoA hydrolase
B1917_RS09145	COG1250	3-hydroxyacyl-CoA dehydrogenase
B1917_RS09150	COG0154	amidase activity
B1917_RS09160	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
B1917_RS09175	COG0495	leucyl-tRNA aminoacylation
B1917_RS09180	COG2814	Major facilitator Superfamily
B1917_RS09210	COG0267	Belongs to the bacterial ribosomal protein bL33 family
B1917_RS09215	COG0227	Belongs to the bacterial ribosomal protein bL28 family
B1917_RS09220	COG2814	Major facilitator Superfamily
B1917_RS09225	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
B1917_RS09240	COG4176	ABC-type proline glycine betaine transport system permease component
B1917_RS09250	COG1942	4-Oxalocrotonate Tautomerase
B1917_RS09255	COG0183	Belongs to the thiolase family
B1917_RS09265	COG1802	Transcriptional regulator
B1917_RS09275	COG1024	Enoyl-CoA hydratase
B1917_RS09290	COG2032	superoxide dismutase activity
B1917_RS09305	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
B1917_RS09330	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B1917_RS09335	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B1917_RS09345	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
B1917_RS09350	COG0736	holo-[acyl-carrier-protein] synthase activity
B1917_RS09355	COG1472	Belongs to the glycosyl hydrolase 3 family
B1917_RS09360	COG0322	excinuclease ABC activity
B1917_RS09365	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
B1917_RS09380	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
B1917_RS09380	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
B1917_RS09385	COG2224	Isocitrate lyase
B1917_RS09405	COG0559	Belongs to the binding-protein-dependent transport system permease family
B1917_RS09415	COG4638	Rieske (2fe-2S)
B1917_RS09425	COG1024	Enoyl-CoA hydratase
B1917_RS09435	COG0633	Ferredoxin
B1917_RS09440	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B1917_RS09455	COG0183	Belongs to the thiolase family
B1917_RS09465	COG4692	amylo-alpha-1,6-glucosidase activity
B1917_RS09470	COG0583	DNA-binding transcription factor activity
B1917_RS09495	COG2346	COG2346, Truncated hemoglobins
B1917_RS09625	COG2207	Transcriptional regulator
B1917_RS09670	COG1132	(ABC) transporter
B1917_RS09695	COG0659	secondary active sulfate transmembrane transporter activity
B1917_RS09725	COG2169	Transcriptional regulator
B1917_RS09730	COG5507	3-demethylubiquinone-9 3-methyltransferase
B1917_RS09735	COG0384	phenazine biosynthesis protein PhzF
B1917_RS09740	COG0583	DNA-binding transcription factor activity
B1917_RS09745	COG2733	membrane
B1917_RS09760	COG1012	belongs to the aldehyde dehydrogenase family
B1917_RS09765	COG3284	Transcriptional regulator
B1917_RS09780	COG1346	cytolysis
B1917_RS09785	COG1380	Effector of murein hydrolase LrgA
B1917_RS09790	COG4106	trans-aconitate 2-methyltransferase activity
B1917_RS09790	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
B1917_RS09800	COG0156	8-amino-7-oxononanoate synthase activity
B1917_RS09870	COG1131	(ABC) transporter
B1917_RS09875	COG0842	Transport permease protein
B1917_RS09880	COG0628	permease
B1917_RS09910	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B1917_RS09920	COG0828	Belongs to the bacterial ribosomal protein bS21 family
B1917_RS09925	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
B1917_RS09930	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
B1917_RS09935	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
B1917_RS09940	COG0330	HflC and HflK could
B1917_RS09945	COG0330	HflC and HflK could
B1917_RS09950	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
B1917_RS09955	COG1923	regulation of RNA biosynthetic process
B1917_RS09960	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
B1917_RS09965	COG1160	GTP binding
B1917_RS09970	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B1917_RS09975	COG2976	Protein conserved in bacteria
B1917_RS09980	COG0124	histidyl-tRNA synthetase
B1917_RS09985	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
B1917_RS09995	COG0820	rRNA (adenine-C2-)-methyltransferase activity
B1917_RS10000	COG0105	UTP biosynthetic process
B1917_RS10005	COG0525	valine-tRNA ligase activity
B1917_RS10020	COG0642	Histidine kinase
B1917_RS10040	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B1917_RS10045	COG0336	Belongs to the RNA methyltransferase TrmD family
B1917_RS10050	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
B1917_RS10055	COG0228	four-way junction DNA binding
B1917_RS10065	COG0425	Belongs to the sulfur carrier protein TusA family
B1917_RS10070	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
B1917_RS10115	COG0154	amidase activity
B1917_RS10120	COG4172	Belongs to the ABC transporter superfamily
B1917_RS10125	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B1917_RS10130	COG0601	transmembrane transport
B1917_RS10135	COG0747	negative chemotaxis
B1917_RS10160	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B1917_RS10170	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
B1917_RS10185	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
B1917_RS10190	COG3395	kinase activity
B1917_RS10205	COG1024	Enoyl-CoA hydratase
B1917_RS10225	COG0633	Ferredoxin
B1917_RS10230	COG0443	Heat shock 70 kDa protein
B1917_RS10235	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
B1917_RS10240	COG0316	Belongs to the HesB IscA family
B1917_RS10245	COG0822	iron-sulfur transferase activity
B1917_RS10250	COG1104	cysteine desulfurase activity
B1917_RS10260	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B1917_RS10265	COG0556	nucleotide-excision repair
B1917_RS10275	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
B1917_RS10280	COG3468	outer membrane autotransporter barrel domain protein
B1917_RS10305	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
B1917_RS10320	COG1960	acyl-CoA dehydrogenase activity
B1917_RS10325	COG1028	Short-chain dehydrogenase reductase Sdr
B1917_RS10330	COG0183	Belongs to the thiolase family
B1917_RS10340	COG1024	Enoyl-CoA hydratase
B1917_RS10355	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B1917_RS10360	COG0583	DNA-binding transcription factor activity
B1917_RS10365	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
B1917_RS10370	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
B1917_RS10375	COG0740	serine-type endopeptidase activity
B1917_RS10380	COG0544	peptidyl-prolyl cis-trans isomerase activity
B1917_RS10390	COG1278	Cold shock
B1917_RS10400	COG1278	Cold shock
B1917_RS10435	COG2171	N-acyltransferase activity
B1917_RS10440	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B1917_RS10445	COG2890	protein-(glutamine-N5) methyltransferase activity
B1917_RS10450	COG0488	(ABC) transporter
B1917_RS10455	COG4771	TonB-dependent receptor
B1917_RS10460	COG0210	DNA helicase
B1917_RS10480	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
B1917_RS10480	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B1917_RS10485	COG0196	riboflavin kinase activity
B1917_RS10490	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
B1917_RS10495	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
B1917_RS10500	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
B1917_RS10510	COG1522	sequence-specific DNA binding
B1917_RS10525	COG2951	lytic endotransglycosylase activity
B1917_RS10530	COG2833	Protein of unknown function (DUF455)
B1917_RS10550	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
B1917_RS10550	COG0189	ligase activity
B1917_RS10555	COG1181	Belongs to the D-alanine--D-alanine ligase family
B1917_RS10555	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
B1917_RS10560	COG3237	CsbD-like
B1917_RS10570	COG2823	Periplasmic or secreted lipoprotein
B1917_RS10585	COG4181	ATPase activity
B1917_RS10595	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B1917_RS10600	COG0584	glycerophosphoryl diester phosphodiesterase
B1917_RS10605	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
B1917_RS10615	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
B1917_RS10615	COG0678	peroxiredoxin activity
B1917_RS10625	COG0789	Transcriptional regulator
B1917_RS10630	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
B1917_RS10660	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
B1917_RS10665	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
B1917_RS10675	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
B1917_RS10680	COG2252	PERMEase
B1917_RS10690	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B1917_RS10720	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B1917_RS10725	COG2358	TRAP transporter, solute receptor (TAXI family
B1917_RS10755	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B1917_RS10760	COG1366	Belongs to the anti-sigma-factor antagonist family
B1917_RS10765	COG2172	sigma factor antagonist activity
B1917_RS10770	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
B1917_RS10780	COG2208	phosphoserine phosphatase activity
B1917_RS10780	COG2770	Histidine kinase
B1917_RS10805	COG1595	DNA-templated transcription, initiation
B1917_RS10820	COG4792	protein secretion
B1917_RS10825	COG4791	protein targeting
B1917_RS10830	COG4794	Type iii secretion
B1917_RS10835	COG4790	Type iii secretion
B1917_RS10870	COG4669	(LipO)protein
B1917_RS10935	COG4789	Type iii secretion
B1917_RS10965	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B1917_RS10970	COG0840	transmembrane signaling receptor activity
B1917_RS10975	COG2233	PERMEase
B1917_RS11000	COG0492	ferredoxin-NADP+ reductase activity
B1917_RS11005	COG1840	ABC-type Fe3 transport system, periplasmic component
B1917_RS11010	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B1917_RS11015	COG1178	ABC-type Fe3 transport system permease component
B1917_RS11020	COG3842	ATPase activity
B1917_RS11025	COG0583	DNA-binding transcription factor activity
B1917_RS11045	COG0501	Belongs to the peptidase M48B family
B1917_RS11055	COG0697	spore germination
B1917_RS11065	COG1846	Transcriptional regulator
B1917_RS11075	COG1566	PFAM secretion protein HlyD family protein
B1917_RS11080	COG2814	Major facilitator Superfamily
B1917_RS11085	COG0473	3-isopropylmalate dehydrogenase activity
B1917_RS11095	COG0747	negative chemotaxis
B1917_RS11105	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B1917_RS11120	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
B1917_RS11145	COG1012	belongs to the aldehyde dehydrogenase family
B1917_RS11155	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B1917_RS11160	COG1115	amino acid carrier protein
B1917_RS11165	COG0433	COG0433 Predicted ATPase
B1917_RS11170	COG0217	transcriptional regulatory protein
B1917_RS11175	COG0151	Belongs to the GarS family
B1917_RS11180	COG0408	coproporphyrinogen oxidase activity
B1917_RS11185	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
B1917_RS11190	COG0799	negative regulation of ribosome biogenesis
B1917_RS11195	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
B1917_RS11200	COG0424	maF-like protein
B1917_RS11205	COG3468	outer membrane autotransporter barrel domain protein
B1917_RS11240	COG1530	ribonuclease E activity
B1917_RS11245	COG0077	Prephenate dehydratase
B1917_RS11260	COG1132	(ABC) transporter
B1917_RS11265	COG0859	PFAM glycosyl transferase family 9
B1917_RS11290	COG2194	sulfuric ester hydrolase activity
B1917_RS11295	COG0438	transferase activity, transferring glycosyl groups
B1917_RS11300	COG0463	Glycosyl transferase, family 2
B1917_RS11305	COG0726	polysaccharide deacetylase
B1917_RS11310	COG0438	transferase activity, transferring glycosyl groups
B1917_RS11325	COG1643	Atp-dependent helicase
B1917_RS11330	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
B1917_RS11330	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
B1917_RS11335	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
B1917_RS11345	COG0704	Plays a role in the regulation of phosphate uptake
B1917_RS11350	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
B1917_RS11355	COG1960	acyl-CoA dehydrogenase activity
B1917_RS11380	COG1177	transmembrane transport
B1917_RS11385	COG1176	ABC-type spermidine putrescine transport system, permease component I
B1917_RS11390	COG3842	ATPase activity
B1917_RS11395	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
B1917_RS11410	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
B1917_RS11415	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B1917_RS11425	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
B1917_RS11425	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
B1917_RS11445	COG0372	Belongs to the citrate synthase family
B1917_RS11450	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
B1917_RS11455	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
B1917_RS11460	COG1053	succinate dehydrogenase
B1917_RS11465	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
B1917_RS11470	COG2009	succinate dehydrogenase
B1917_RS11475	COG2188	Transcriptional regulator
B1917_RS11480	COG0039	L-malate dehydrogenase activity
B1917_RS11510	COG1981	membrane
B1917_RS11535	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B1917_RS11545	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
B1917_RS11575	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
B1917_RS11580	COG0148	phosphopyruvate hydratase activity
B1917_RS11590	COG2877	3-deoxy-8-phosphooctulonate synthase activity
B1917_RS11595	COG0504	CTP synthase activity
B1917_RS11620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B1917_RS11630	COG0747	negative chemotaxis
B1917_RS11635	COG4172	Belongs to the ABC transporter superfamily
B1917_RS11640	COG1446	asparaginase
B1917_RS11670	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
B1917_RS11685	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
B1917_RS11690	COG0697	spore germination
B1917_RS11695	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B1917_RS11705	COG3193	protein, possibly involved in utilization of glycolate and propanediol
B1917_RS11710	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B1917_RS11715	COG0791	NLP P60 protein
B1917_RS11730	COG0583	DNA-binding transcription factor activity
B1917_RS11745	COG0583	DNA-binding transcription factor activity
B1917_RS11755	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
B1917_RS11770	COG0670	Belongs to the BI1 family
B1917_RS11775	COG3181	Tripartite tricarboxylate transporter family receptor
B1917_RS11790	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B1917_RS11800	COG1381	Involved in DNA repair and RecF pathway recombination
B1917_RS11805	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
B1917_RS11810	COG0571	ribonuclease III activity
B1917_RS11815	COG0681	Belongs to the peptidase S26 family
B1917_RS11820	COG0481	GTPase activity
B1917_RS11825	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B1917_RS11850	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B1917_RS11855	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B1917_RS11870	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B1917_RS11875	COG0416	fatty acid biosynthetic process
B1917_RS11880	COG0333	Belongs to the bacterial ribosomal protein bL32 family
B1917_RS11885	COG1399	metal-binding, possibly nucleic acid-binding protein
B1917_RS11890	COG0424	maF-like protein
B1917_RS11900	COG3023	N-Acetylmuramoyl-L-alanine amidase
B1917_RS11905	COG1289	transmembrane transporter activity
B1917_RS11915	COG3022	response to hydroperoxide
B1917_RS11930	COG0135	phosphoribosylanthranilate isomerase activity
B1917_RS11945	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
B1917_RS11950	COG0101	tRNA pseudouridine synthase activity
B1917_RS11960	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
B1917_RS11965	COG0473	3-isopropylmalate dehydrogenase activity
B1917_RS11970	COG0066	3-isopropylmalate dehydratase activity
B1917_RS11975	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
B1917_RS11985	COG1122	ATPase activity
B1917_RS12015	COG0437	4 iron, 4 sulfur cluster binding
B1917_RS12020	COG0243	molybdopterin cofactor binding
B1917_RS12020	COG3383	formate dehydrogenase (NAD+) activity
B1917_RS12050	COG0489	protein tyrosine kinase activity
B1917_RS12055	COG0746	molybdenum cofactor guanylyltransferase activity
B1917_RS12060	COG0303	'Molybdopterin
B1917_RS12065	COG1763	Mo-molybdopterin cofactor biosynthetic process
B1917_RS12075	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
B1917_RS12080	COG5001	Diguanylate cyclase
B1917_RS12100	COG3842	ATPase activity
B1917_RS12110	COG0406	alpha-ribazole phosphatase activity
B1917_RS12120	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
B1917_RS12125	COG0505	Belongs to the CarA family
B1917_RS12130	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
B1917_RS12160	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
B1917_RS12165	COG1960	acyl-CoA dehydrogenase activity
B1917_RS12175	COG2867	negative regulation of translational initiation
B1917_RS12185	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
B1917_RS12190	COG3706	GGDEF domain
B1917_RS12195	COG0330	HflC and HflK could
B1917_RS12210	COG0519	Catalyzes the synthesis of GMP from XMP
B1917_RS12210	COG0518	GMP synthase (glutamine-hydrolyzing) activity
B1917_RS12220	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
B1917_RS12225	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B1917_RS12230	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
B1917_RS12235	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B1917_RS12245	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
B1917_RS12250	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B1917_RS12255	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
B1917_RS12260	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B1917_RS12265	COG0750	zinc metalloprotease
B1917_RS12270	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
B1917_RS12280	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
B1917_RS12285	COG0233	cytoplasmic translational termination
B1917_RS12290	COG0528	UMP kinase activity
B1917_RS12295	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
B1917_RS12300	COG0052	Belongs to the universal ribosomal protein uS2 family
B1917_RS12305	COG0024	Methionine aminopeptidase
B1917_RS12310	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
B1917_RS12340	COG0285	dihydrofolate synthase activity
B1917_RS12375	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
B1917_RS12385	COG1677	Flagellar hook-basal body complex protein FliE
B1917_RS12395	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B1917_RS12405	COG1157	protein secretion by the type III secretion system
B1917_RS12430	COG1580	Controls the rotational direction of flagella during chemotaxis
B1917_RS12450	COG1338	Plays a role in the flagellum-specific transport system
B1917_RS12470	COG0840	transmembrane signaling receptor activity
B1917_RS12475	COG0840	transmembrane signaling receptor activity
B1917_RS12480	COG0840	transmembrane signaling receptor activity
B1917_RS12490	COG1256	bacterial-type flagellum assembly
B1917_RS12500	COG1706	bacterial-type flagellum-dependent cell motility
B1917_RS12505	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
B1917_RS12520	COG1749	Flagellar hook protein flgE
B1917_RS12530	COG1558	bacterial-type flagellum-dependent cell motility
B1917_RS12535	COG1815	bacterial-type flagellum-dependent cell motility
B1917_RS12575	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B1917_RS12580	COG0765	amino acid transport
B1917_RS12585	COG1126	abc transporter atp-binding protein
B1917_RS12600	COG4948	Mandelate Racemase Muconate Lactonizing
B1917_RS12605	COG3181	Tripartite tricarboxylate transporter family receptor
B1917_RS12615	COG0066	3-isopropylmalate dehydratase activity
B1917_RS12630	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B1917_RS12640	COG3181	Tripartite tricarboxylate transporter family receptor
B1917_RS12650	COG1802	Transcriptional regulator
B1917_RS12665	COG0583	DNA-binding transcription factor activity
B1917_RS12685	COG1695	Transcriptional regulator
B1917_RS12690	COG3568	Endonuclease Exonuclease Phosphatase
B1917_RS12695	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B1917_RS12710	COG0392	lysyltransferase activity
B1917_RS12750	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
B1917_RS12760	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
B1917_RS12770	COG1640	4-alpha-glucanotransferase
B1917_RS12785	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
B1917_RS12815	COG0667	Aldo Keto reductase
B1917_RS12830	COG2259	Doxx family
B1917_RS12860	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B1917_RS12880	COG0386	Belongs to the glutathione peroxidase family
B1917_RS12885	COG0625	glutathione transferase activity
B1917_RS12900	COG0095	Lipoate-protein ligase
B1917_RS12915	COG0688	phosphatidylethanolamine metabolic process
B1917_RS12925	COG1464	Belongs to the NlpA lipoprotein family
B1917_RS12940	COG2363	Small membrane protein
B1917_RS12965	COG3842	ATPase activity
B1917_RS12970	COG0395	ABC-type sugar transport system, permease component
B1917_RS12975	COG1175	transmembrane transport
B1917_RS12980	COG1653	transport
B1917_RS12990	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
B1917_RS13005	COG0559	Belongs to the binding-protein-dependent transport system permease family
B1917_RS13025	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
B1917_RS13040	COG0697	spore germination
B1917_RS13050	COG2311	Membrane
B1917_RS13075	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
B1917_RS13085	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
B1917_RS13090	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
B1917_RS13095	COG1760	l-serine dehydratase
B1917_RS13100	COG1283	sodium-dependent phosphate transmembrane transporter activity
B1917_RS13105	COG0412	Dienelactone hydrolase
B1917_RS13120	COG1611	Belongs to the LOG family
B1917_RS13140	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
B1917_RS13145	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
B1917_RS13150	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
B1917_RS13155	COG2251	uridine kinase activity
B1917_RS13155	COG0195	Participates in both transcription termination and antitermination
B1917_RS13160	COG0779	Required for maturation of 30S ribosomal subunits
B1917_RS13165	COG1187	pseudouridine synthase activity
B1917_RS13170	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
B1917_RS13180	COG0583	DNA-binding transcription factor activity
B1917_RS13190	COG0523	cobalamin synthesis protein
B1917_RS13210	COG0625	glutathione transferase activity
B1917_RS13215	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
B1917_RS13220	COG1047	Peptidyl-prolyl cis-trans
B1917_RS13225	COG2003	Belongs to the UPF0758 family
B1917_RS13230	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
B1917_RS13235	COG3483	tryptophan 2,3-dioxygenase activity
B1917_RS13240	COG0254	rRNA binding
B1917_RS13250	COG0534	Mate efflux family protein
B1917_RS13270	COG2304	oxidoreductase activity
B1917_RS13290	COG1028	Short-chain dehydrogenase reductase Sdr
B1917_RS13295	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
B1917_RS13300	COG1562	ergosterol biosynthetic process
B1917_RS13305	COG1562	ergosterol biosynthetic process
B1917_RS13310	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
B1917_RS13310	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
B1917_RS13315	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
B1917_RS13325	COG0842	Transport permease protein
B1917_RS13330	COG1131	(ABC) transporter
B1917_RS13350	COG1477	protein flavinylation
B1917_RS13365	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
B1917_RS13380	COG5564	TIM-barrel signal transduction protein
B1917_RS13385	COG5441	Belongs to the UPF0261 family
B1917_RS13395	COG3468	outer membrane autotransporter barrel domain protein
B1917_RS13400	COG3468	outer membrane autotransporter barrel domain protein
B1917_RS13410	COG0542	response to heat
B1917_RS13415	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B1917_RS13430	COG0494	nUDIX hydrolase
B1917_RS13435	COG3530	Putative quorum-sensing-regulated virulence factor
B1917_RS13445	COG1595	DNA-templated transcription, initiation
B1917_RS13450	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B1917_RS13485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B1917_RS13490	COG0765	amino acid transport
B1917_RS13495	COG0765	amino acid transport
B1917_RS13520	COG2988	succinylglutamate desuccinylase activity
B1917_RS13545	COG3181	Tripartite tricarboxylate transporter family receptor
B1917_RS13550	COG2084	Dehydrogenase
B1917_RS13565	COG1619	proteins homologs of microcin C7 resistance protein MccF
B1917_RS13580	COG2814	Major facilitator Superfamily
B1917_RS13590	COG0583	DNA-binding transcription factor activity
B1917_RS13630	COG0672	)-iron permease
B1917_RS13645	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
B1917_RS13650	COG1028	Short-chain dehydrogenase reductase Sdr
B1917_RS13655	COG3243	poly(R)-hydroxyalkanoic acid synthase
B1917_RS13665	COG0564	pseudouridine synthase activity
B1917_RS13675	COG1199	ATP-dependent helicase activity
B1917_RS13680	COG2183	response to ionizing radiation
B1917_RS13685	COG0180	Tryptophanyl-tRNA synthetase
B1917_RS13705	COG3181	Tripartite tricarboxylate transporter family receptor
B1917_RS13715	COG0583	DNA-binding transcription factor activity
B1917_RS13720	COG1028	Short-chain dehydrogenase reductase Sdr
B1917_RS13725	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
B1917_RS13730	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B1917_RS13735	COG0508	dehydrogenase complex catalyzes the overall conversion of
B1917_RS13740	COG0567	Dehydrogenase, E1 component
B1917_RS13745	COG1297	OPT oligopeptide transporter protein
B1917_RS13750	COG1297	OPT oligopeptide transporter protein
B1917_RS13755	COG1522	sequence-specific DNA binding
B1917_RS13765	COG0280	phosphate acetyltransferase
B1917_RS13765	COG0281	malic enzyme
B1917_RS13770	COG3539	Fimbrial protein
B1917_RS13785	COG0613	PHP domain protein
B1917_RS13820	COG0084	hydrolase, TatD family'
B1917_RS13825	COG1136	(ABC) transporter
B1917_RS13840	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
B1917_RS13845	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
B1917_RS13850	COG1028	Short-chain dehydrogenase reductase Sdr
B1917_RS13855	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
B1917_RS13870	COG1022	Amp-dependent synthetase and ligase
B1917_RS13905	COG2205	protein histidine kinase activity
B1917_RS13910	COG0745	RESPONSE REGULATOR receiver
B1917_RS13915	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
B1917_RS13925	COG1295	ribonuclease BN
B1917_RS13940	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
B1917_RS13965	COG1534	Rna-binding protein
B1917_RS13970	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
B1917_RS13975	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B1917_RS13985	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B1917_RS13995	COG0248	Ppx GppA phosphatase
B1917_RS14020	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
B1917_RS14035	COG2732	(Barnase) inhibitor
B1917_RS14045	COG0281	malic enzyme
B1917_RS14045	COG0280	phosphate acetyltransferase
B1917_RS14055	COG0436	Aminotransferase
B1917_RS14060	COG0741	lytic transglycosylase activity
B1917_RS14065	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
B1917_RS14090	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
B1917_RS14090	COG1648	precorrin-2 dehydrogenase activity
B1917_RS14095	COG3468	outer membrane autotransporter barrel domain protein
B1917_RS14105	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
B1917_RS14110	COG2027	D-alanyl-D-alanine carboxypeptidase
B1917_RS14115	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
B1917_RS14120	COG0343	queuine tRNA-ribosyltransferase activity
B1917_RS14125	COG1862	Preprotein translocase
B1917_RS14130	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B1917_RS14135	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B1917_RS14150	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
B1917_RS14155	COG1702	phosphate starvation-inducible protein PhoH
B1917_RS14160	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
B1917_RS14165	COG4535	Mg2 and Co2 transporter CorC
B1917_RS14175	COG0667	Aldo Keto reductase
B1917_RS14200	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
B1917_RS14205	COG0745	RESPONSE REGULATOR receiver
B1917_RS14210	COG2201	protein-glutamate methylesterase activity
B1917_RS14220	COG0840	transmembrane signaling receptor activity
B1917_RS14235	COG0745	RESPONSE REGULATOR receiver
B1917_RS14270	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
B1917_RS14280	COG0739	heme binding
B1917_RS14290	COG0521	Mo-molybdopterin cofactor biosynthetic process
B1917_RS14300	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
B1917_RS14330	COG0625	glutathione transferase activity
B1917_RS14345	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
B1917_RS14350	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
B1917_RS14355	COG0126	phosphoglycerate kinase activity
B1917_RS14360	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
B1917_RS14365	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
B1917_RS14370	COG1385	rRNA (uridine-N3-)-methyltransferase activity
B1917_RS14380	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
B1917_RS14385	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B1917_RS14390	COG0508	dehydrogenase complex catalyzes the overall conversion of
B1917_RS14395	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
B1917_RS14405	COG4566	intracellular signal transduction
B1917_RS14410	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
B1917_RS14415	COG0339	signal peptide processing
B1917_RS14420	COG1999	signal sequence binding
B1917_RS14440	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B1917_RS14450	COG1187	pseudouridine synthase activity
B1917_RS14455	COG3161	chorismate lyase activity
B1917_RS14460	COG2814	Major facilitator Superfamily
B1917_RS14470	COG0667	Aldo Keto reductase
B1917_RS14485	COG0335	large ribosomal subunit rRNA binding
B1917_RS14515	COG0175	sulfate reduction
B1917_RS14520	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
B1917_RS14525	COG4208	sulfate ABC transporter
B1917_RS14530	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
B1917_RS14545	COG0450	alkyl hydroperoxide reductase
B1917_RS14550	COG1960	acyl-CoA dehydrogenase activity
B1917_RS14565	COG0123	including yeast histone deacetylase and acetoin utilization protein
B1917_RS14570	COG2951	lytic endotransglycosylase activity
B1917_RS14590	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B1917_RS14595	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
B1917_RS14600	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
B1917_RS14620	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
B1917_RS14625	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
B1917_RS14630	COG0287	Prephenate dehydrogenase
B1917_RS14640	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
B1917_RS14655	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
B1917_RS14665	COG2814	Major facilitator Superfamily
B1917_RS14685	COG0583	DNA-binding transcription factor activity
B1917_RS14720	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
B1917_RS14735	COG0667	Aldo Keto reductase
B1917_RS14745	COG5265	(ABC) transporter
B1917_RS14790	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B1917_RS14795	COG0439	Biotin carboxylase
B1917_RS14800	COG2188	Transcriptional regulator
B1917_RS14825	COG0511	ligase activity, forming carbon-carbon bonds
B1917_RS14835	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
B1917_RS14855	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
B1917_RS14870	COG0500	methyltransferase
B1917_RS14875	COG5265	(ABC) transporter
B1917_RS14890	COG0028	Belongs to the TPP enzyme family
B1917_RS14895	COG0440	acetolactate synthase activity
B1917_RS14900	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
B1917_RS14905	COG1183	phosphatidylcholine synthase activity
B1917_RS14915	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
B1917_RS14920	COG1185	polyribonucleotide nucleotidyltransferase activity
B1917_RS14935	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B1917_RS14955	COG0149	triose-phosphate isomerase activity
B1917_RS14960	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
B1917_RS14970	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
B1917_RS14980	COG3799	methylaspartate ammonia-lyase activity
B1917_RS15020	COG0583	DNA-binding transcription factor activity
B1917_RS15025	COG0626	cystathionine gamma-synthase activity
B1917_RS15030	COG3608	succinylglutamate desuccinylase aspartoacylase
B1917_RS15050	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B1917_RS15070	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
B1917_RS15085	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B1917_RS15090	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B1917_RS15095	COG1733	regulation of RNA biosynthetic process
B1917_RS15105	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
B1917_RS15110	COG0583	DNA-binding transcription factor activity
B1917_RS15115	COG1597	lipid kinase activity
B1917_RS15125	COG0671	phosphoesterase, PA-phosphatase related
B1917_RS15150	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
B1917_RS15155	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B1917_RS15160	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B1917_RS15165	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B1917_RS15170	COG0649	NAD binding
B1917_RS15175	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
B1917_RS15185	COG1034	ATP synthesis coupled electron transport
B1917_RS15190	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
B1917_RS15195	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B1917_RS15205	COG0713	ATP synthesis coupled electron transport
B1917_RS15220	COG1007	ATP synthesis coupled electron transport
B1917_RS15230	COG4774	siderophore transport
B1917_RS15235	COG4774	siderophore transport
B1917_RS15250	COG0028	Belongs to the TPP enzyme family
B1917_RS15255	COG3181	Tripartite tricarboxylate transporter family receptor
B1917_RS15260	COG0583	DNA-binding transcription factor activity
B1917_RS15265	COG0560	Phosphoserine phosphatase
B1917_RS15270	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
B1917_RS15275	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
B1917_RS15280	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
B1917_RS15290	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
B1917_RS15295	COG0308	aminopeptidase N
B1917_RS15315	COG0028	Belongs to the TPP enzyme family
B1917_RS15335	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B1917_RS15345	COG0318	PFAM AMP-dependent synthetase and ligase
B1917_RS15355	COG1802	Transcriptional regulator
B1917_RS15365	COG1802	Transcriptional regulator
B1917_RS15375	COG1028	Short-chain dehydrogenase reductase Sdr
B1917_RS15395	COG1126	abc transporter atp-binding protein
B1917_RS15400	COG0765	amino acid transport
B1917_RS15420	COG1538	Outer membrane efflux protein
B1917_RS15425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B1917_RS15430	COG2274	protein secretion by the type I secretion system
B1917_RS15435	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
B1917_RS15445	COG2994	toxin metabolic process
B1917_RS15460	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B1917_RS15465	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
B1917_RS15475	COG0583	DNA-binding transcription factor activity
B1917_RS15485	COG0142	geranyltranstransferase activity
B1917_RS15495	COG0261	This protein binds to 23S rRNA in the presence of protein L20
B1917_RS15500	COG0211	Belongs to the bacterial ribosomal protein bL27 family
B1917_RS15505	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
B1917_RS15510	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
B1917_RS15550	COG3712	iron ion homeostasis
B1917_RS15555	COG4774	siderophore transport
B1917_RS15560	COG2353	YceI-like domain
B1917_RS15580	COG0019	diaminopimelate decarboxylase activity
B1917_RS15600	COG0747	negative chemotaxis
B1917_RS15605	COG0601	transmembrane transport
B1917_RS15610	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B1917_RS15620	COG0154	amidase activity
B1917_RS15625	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B1917_RS15650	COG2154	pterin-4-alpha-carbinolamine dehydratase
B1917_RS15660	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
B1917_RS15670	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
B1917_RS15675	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B1917_RS15680	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
B1917_RS15685	COG1929	Belongs to the glycerate kinase type-1 family
B1917_RS15690	COG0469	pyruvate kinase activity
B1917_RS15695	COG0700	Nucleoside recognition
B1917_RS15725	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
B1917_RS15730	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B1917_RS15745	COG0823	Involved in the tonB-independent uptake of proteins
B1917_RS15755	COG0848	biopolymer transport protein
B1917_RS15760	COG0811	peptide transport
B1917_RS15765	COG0824	Thioesterase
B1917_RS15770	COG0442	prolyl-tRNA aminoacylation
B1917_RS15775	COG0494	nUDIX hydrolase
B1917_RS15790	COG2135	peptidase activity
B1917_RS15855	COG1196	nuclear chromosome segregation
B1917_RS15995	COG1464	Belongs to the NlpA lipoprotein family
B1917_RS16025	COG4211	Belongs to the binding-protein-dependent transport system permease family
B1917_RS16035	COG0154	amidase activity
B1917_RS16040	COG0288	reversible hydration of carbon dioxide
B1917_RS16055	COG0514	ATP-dependent DNA helicase (RecQ)
B1917_RS16060	COG2255	four-way junction helicase activity
B1917_RS16075	COG0632	four-way junction helicase activity
B1917_RS16080	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
B1917_RS16100	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B1917_RS16110	COG0006	proline dipeptidase activity
B1917_RS16135	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
B1917_RS16150	COG4783	chaperone-mediated protein folding
B1917_RS16155	COG0429	hydrolase of the alpha beta-hydrolase fold
B1917_RS16185	COG0513	Belongs to the DEAD box helicase family
B1917_RS16205	COG1058	Belongs to the CinA family
B1917_RS16205	COG1546	Belongs to the CinA family
B1917_RS16210	COG1414	Transcriptional regulator
B1917_RS16230	COG0167	dihydroorotate dehydrogenase activity
B1917_RS16235	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
B1917_RS16245	COG0583	DNA-binding transcription factor activity
B1917_RS16305	COG0280	phosphate acetyltransferase
B1917_RS16305	COG0281	malic enzyme
B1917_RS16315	COG0601	transmembrane transport
B1917_RS16320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B1917_RS16325	COG4172	Belongs to the ABC transporter superfamily
B1917_RS16355	COG0640	Transcriptional regulator
B1917_RS16370	COG3135	benzoate transporter
B1917_RS16375	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
B1917_RS16380	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
B1917_RS16385	COG0742	ribosomal rna small subunit methyltransferase
B1917_RS16405	COG3639	organic phosphonate transmembrane transporter activity
B1917_RS16410	COG3639	organic phosphonate transmembrane transporter activity
B1917_RS16415	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
B1917_RS16450	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
B1917_RS16455	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B1917_RS16465	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
B1917_RS16470	COG1058	Belongs to the CinA family
B1917_RS16470	COG1546	Belongs to the CinA family
B1917_RS16475	COG0284	orotidine-5'-phosphate decarboxylase activity
B1917_RS16480	COG1252	NADH dehydrogenase
B1917_RS16495	COG3468	outer membrane autotransporter barrel domain protein
B1917_RS16500	COG0459	protein refolding
B1917_RS16505	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
B1917_RS16525	COG1053	succinate dehydrogenase
B1917_RS16535	COG0583	DNA-binding transcription factor activity
B1917_RS16540	COG1053	succinate dehydrogenase
B1917_RS16560	COG3706	GGDEF domain
B1917_RS16595	COG1262	PFAM Formylglycine-generating sulfatase enzyme
B1917_RS16600	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
B1917_RS16610	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B1917_RS16620	COG0069	glutamate synthase activity
B1917_RS16625	COG2391	methyltransferase activity
B1917_RS16630	COG0679	Auxin Efflux Carrier
B1917_RS16655	COG0557	exoribonuclease II activity
B1917_RS16660	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B1917_RS16670	COG3128	pkhd-type hydroxylase
B1917_RS16675	COG0776	regulation of translation
B1917_RS16705	COG0642	Histidine kinase
B1917_RS16710	COG3158	transport of potassium into the cell
B1917_RS16715	COG0137	argininosuccinate synthase activity
B1917_RS16720	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
B1917_RS16725	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B1917_RS16735	COG0583	DNA-binding transcription factor activity
B1917_RS16745	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B1917_RS16765	COG2186	Transcriptional regulator
B1917_RS16775	COG2223	nitrite transmembrane transporter activity
B1917_RS16785	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B1917_RS16790	COG0450	alkyl hydroperoxide reductase
B1917_RS16810	COG1214	PFAM Peptidase M22, glycoprotease
B1917_RS16815	COG1573	uracil-dna glycosylase
B1917_RS16820	COG0477	Major facilitator Superfamily
B1917_RS16825	COG1196	nuclear chromosome segregation
B1917_RS16835	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
B1917_RS16840	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B1917_RS16855	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B1917_RS16860	COG1122	ATPase activity
B1917_RS16865	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
B1917_RS16870	COG1268	BioY protein
B1917_RS16890	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B1917_RS16925	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
B1917_RS16930	COG2878	Part of a membrane complex involved in electron transport
B1917_RS16945	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
B1917_RS16950	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
B1917_RS16955	COG0251	oxidation-reduction process
B1917_RS16965	COG3228	Belongs to the MtfA family
B1917_RS16970	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B1917_RS16980	COG0133	tryptophan synthase activity
B1917_RS16985	COG0159	tryptophan synthase activity
B1917_RS16990	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
B1917_RS16995	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
B1917_RS17010	COG1530	ribonuclease E activity
B1917_RS17020	COG0546	phosphoglycolate phosphatase activity
B1917_RS17025	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
B1917_RS17030	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
B1917_RS17040	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B1917_RS17045	COG0583	DNA-binding transcription factor activity
B1917_RS17055	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B1917_RS17080	COG0251	oxidation-reduction process
B1917_RS17085	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B1917_RS17085	COG1017	nitric oxide dioxygenase activity
B1917_RS17090	COG2031	fatty acid transporter
B1917_RS17095	COG1012	belongs to the aldehyde dehydrogenase family
B1917_RS17100	COG1802	Transcriptional regulator
B1917_RS17110	COG1278	Cold shock
B1917_RS17115	COG0583	DNA-binding transcription factor activity
B1917_RS17130	COG0183	Belongs to the thiolase family
B1917_RS17140	COG1960	acyl-CoA dehydrogenase activity
B1917_RS17145	COG0583	DNA-binding transcription factor activity
B1917_RS17150	COG3181	Tripartite tricarboxylate transporter family receptor
B1917_RS17155	COG1024	Enoyl-CoA hydratase
B1917_RS17160	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B1917_RS17165	COG1253	flavin adenine dinucleotide binding
B1917_RS17170	COG1285	pathogenesis
B1917_RS17180	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B1917_RS17195	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
B1917_RS17205	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B1917_RS17215	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B1917_RS17220	COG3181	Tripartite tricarboxylate transporter family receptor
B1917_RS17225	COG1960	acyl-CoA dehydrogenase activity
B1917_RS17245	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B1917_RS17250	COG1024	Enoyl-CoA hydratase
B1917_RS17255	COG1960	acyl-CoA dehydrogenase activity
B1917_RS17275	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
B1917_RS17280	COG0022	dehydrogenase e1 component
B1917_RS17285	COG1024	Enoyl-CoA hydratase
B1917_RS17290	COG0508	dehydrogenase complex catalyzes the overall conversion of
B1917_RS17310	COG0683	leucine binding
B1917_RS17315	COG0559	Belongs to the binding-protein-dependent transport system permease family
B1917_RS17320	COG0411	ABC transporter
B1917_RS17330	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B1917_RS17345	COG3181	Tripartite tricarboxylate transporter family receptor
B1917_RS17370	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
B1917_RS17375	COG0793	Belongs to the peptidase S41A family
B1917_RS17380	COG4942	peptidase
B1917_RS17385	COG0588	phosphoglycerate mutase activity
B1917_RS17390	COG1054	Belongs to the UPF0176 family
B1917_RS17395	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
B1917_RS17400	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
B1917_RS17405	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
B1917_RS17410	COG3181	Tripartite tricarboxylate transporter family receptor
B1917_RS17425	COG2226	methyltransferase
B1917_RS17430	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
B1917_RS17445	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B1917_RS17450	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
B1917_RS17475	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
B1917_RS17500	COG1335	isochorismatase
B1917_RS17505	COG2309	aminopeptidase activity
B1917_RS17510	COG0596	Alpha beta hydrolase
B1917_RS17515	COG3473	Maleate cis-trans isomerase
B1917_RS17525	COG2068	MobA-Related Protein
B1917_RS17550	COG2204	response regulator
B1917_RS17555	COG5000	phosphorelay sensor kinase activity
B1917_RS17565	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B1917_RS17565	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
B1917_RS17575	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
B1917_RS17595	COG0583	DNA-binding transcription factor activity
B1917_RS17610	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
B1917_RS17615	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B1917_RS17620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B1917_RS17635	COG0758	DNA mediated transformation
B1917_RS17640	COG1522	sequence-specific DNA binding
B1917_RS17650	COG0242	peptide deformylase activity
B1917_RS17660	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
B1917_RS17670	COG0546	phosphoglycolate phosphatase activity
B1917_RS17690	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
B1917_RS17695	COG1942	4-Oxalocrotonate Tautomerase
B1917_RS17700	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B1917_RS17720	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B1917_RS17740	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B1917_RS17745	COG1024	Enoyl-CoA hydratase
B1917_RS17750	COG1414	Transcriptional regulator
B1917_RS17755	COG0318	PFAM AMP-dependent synthetase and ligase
B1917_RS17760	COG3181	Tripartite tricarboxylate transporter family receptor
B1917_RS17790	COG0583	DNA-binding transcription factor activity
B1917_RS17805	COG3422	double-strand break repair
B1917_RS17810	COG0330	HflC and HflK could
B1917_RS17820	COG0251	oxidation-reduction process
B1917_RS17865	COG3723	Recombinational DNA repair protein, rece pathway
B1917_RS17900	COG0582	viral genome integration into host DNA
B1917_RS17925	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
B1917_RS17935	COG0706	membrane insertase activity
B1917_RS17940	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
B1917_RS17945	COG0594	ribonuclease P activity
B1917_RS17950	COG0230	Belongs to the bacterial ribosomal protein bL34 family
B1917_RS17955	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
B1917_RS17970	COG1414	Transcriptional regulator
B1917_RS17975	COG0154	amidase activity
B1917_RS17990	COG1304	FMN binding
B1917_RS18010	COG1960	acyl-CoA dehydrogenase activity
B1917_RS18030	COG1960	acyl-CoA dehydrogenase activity
B1917_RS18040	COG0183	Belongs to the thiolase family
B1917_RS18045	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B1917_RS18060	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B1917_RS18065	COG3181	Tripartite tricarboxylate transporter family receptor
B1917_RS18075	COG2358	TRAP transporter, solute receptor (TAXI family
B1917_RS18085	COG1629	transport
B1917_RS18090	COG2922	Belongs to the Smg family
B1917_RS18115	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
B1917_RS18120	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B1917_RS18125	COG1028	Short-chain dehydrogenase reductase Sdr
B1917_RS18130	COG1012	belongs to the aldehyde dehydrogenase family
B1917_RS18140	COG0028	Belongs to the TPP enzyme family
B1917_RS18145	COG1522	sequence-specific DNA binding
B1917_RS18150	COG3781	membrane
B1917_RS18160	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
B1917_RS18180	COG4206	TonB-dependent receptor
B1917_RS18185	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B1917_RS18190	COG2022	thiamine diphosphate biosynthetic process
B1917_RS18195	COG0351	phosphomethylpyrimidine kinase
B1917_RS18200	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
B1917_RS18215	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
B1917_RS18225	COG0628	permease
B1917_RS18235	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
B1917_RS18245	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
B1917_RS18250	COG0049	tRNA binding
B1917_RS18255	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
B1917_RS18260	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
B1917_RS18265	COG0051	transcription antitermination factor activity, RNA binding
B1917_RS18270	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
B1917_RS18275	COG0088	Forms part of the polypeptide exit tunnel
B1917_RS18280	COG0089	rRNA binding
B1917_RS18285	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
B1917_RS18290	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
B1917_RS18295	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
B1917_RS18300	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
B1917_RS18305	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
B1917_RS18310	COG0255	Belongs to the universal ribosomal protein uL29 family
B1917_RS18315	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
B1917_RS18335	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
B1917_RS18340	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
B1917_RS18345	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
B1917_RS18350	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
B1917_RS18355	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
B1917_RS18360	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
B1917_RS18365	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
B1917_RS18370	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
B1917_RS18375	COG1841	ribosomal large subunit assembly
B1917_RS18380	COG0200	Binds to the 23S rRNA
B1917_RS18385	COG0201	protein transport
B1917_RS18390	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
B1917_RS18395	COG0257	Belongs to the bacterial ribosomal protein bL36 family
B1917_RS18400	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
B1917_RS18405	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
B1917_RS18410	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
B1917_RS18415	COG0202	RNA polymerase activity
B1917_RS18420	COG0203	ribosomal protein L17
B1917_RS18430	COG1324	tolerance protein
B1917_RS18435	COG4232	protein-disulfide reductase activity
B1917_RS18450	COG0218	Necessary for normal cell division and for the maintenance of normal septation
B1917_RS18460	COG1333	cytochrome c biogenesis protein
B1917_RS18465	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B1917_RS18475	COG1965	Belongs to the frataxin family
B1917_RS18485	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
B1917_RS18490	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
B1917_RS18495	COG0232	Belongs to the dGTPase family. Type 2 subfamily
B1917_RS18510	COG2814	Major facilitator Superfamily
B1917_RS18515	COG0629	single-stranded DNA binding
B1917_RS18555	COG0402	S-adenosylhomocysteine deaminase activity
B1917_RS18565	COG0438	transferase activity, transferring glycosyl groups
B1917_RS18585	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B1917_RS18610	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
B1917_RS18615	COG2186	Transcriptional regulator
B1917_RS18635	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B1917_RS18640	COG1956	GAF domain-containing protein
B1917_RS18645	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B1917_RS18655	COG1652	LysM domain
B1917_RS18670	COG0220	tRNA (guanine-N7-)-methyltransferase activity
B1917_RS18685	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B1917_RS18710	COG3181	Tripartite tricarboxylate transporter family receptor
B1917_RS18725	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B1917_RS18740	COG1024	Enoyl-CoA hydratase
B1917_RS18755	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B1917_RS18760	COG1309	transcriptional regulator
B1917_RS18765	COG2816	NAD+ diphosphatase activity
B1917_RS18770	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B1917_RS18860	COG2814	Major facilitator Superfamily
B1917_RS18865	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
B1917_RS18885	COG1999	signal sequence binding
B1917_RS18890	COG0109	protoheme IX farnesyltransferase activity
B1917_RS18930	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B1917_RS18950	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
B1917_RS18955	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B1917_RS18965	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
B1917_RS18970	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
B1917_RS18980	COG0070	glutamate synthase
B1917_RS18980	COG0069	glutamate synthase activity
B1917_RS18980	COG0067	glutamate synthase
B1917_RS18990	COG3047	cAMP biosynthetic process
B1917_RS19000	COG1127	ABC transporter
B1917_RS19005	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
B1917_RS19010	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
B1917_RS19015	COG2853	Lipoprotein
B1917_RS19025	COG1131	(ABC) transporter
B1917_RS19030	COG0842	Transport permease protein
B1917_RS19040	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
B1917_RS19045	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
B1917_RS19050	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
B1917_RS19055	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
B1917_RS19060	COG0131	Imidazoleglycerol-phosphate dehydratase
B1917_RS19065	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
B1917_RS19070	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
B1917_RS19075	COG0107	imidazoleglycerol-phosphate synthase activity
B1917_RS19080	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
B1917_RS19085	COG0140	phosphoribosyl-ATP diphosphatase activity
B1917_RS19090	COG0537	adenosine 5'-monophosphoramidase activity
B1917_RS19095	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B1917_RS19100	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B1917_RS19115	COG3181	Tripartite tricarboxylate transporter family receptor
B1917_RS19150	COG3702	type iv secretory pathway
B1917_RS19155	COG3451	type IV secretory pathway VirB4
B1917_RS19170	COG3736	Type IV secretory pathway, component VirB8
B1917_RS19175	COG3504	Conjugal transfer protein
B1917_RS19180	COG2948	multi-organism process
B1917_RS19185	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
B1917_RS19195	COG0697	spore germination
B1917_RS19215	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
B1917_RS19220	COG0747	negative chemotaxis
B1917_RS19225	COG0601	transmembrane transport
B1917_RS19230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B1917_RS19235	COG0444	Belongs to the ABC transporter superfamily
B1917_RS19245	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
B1917_RS19255	COG0494	nUDIX hydrolase
B1917_RS19290	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
B1917_RS19295	COG0237	dephospho-CoA kinase activity
B1917_RS19300	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
B1917_RS19315	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
B1917_RS19320	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
B1917_RS19330	COG0477	Major facilitator Superfamily
B1917_RS19335	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
B1917_RS19350	COG1126	abc transporter atp-binding protein
B1917_RS19355	COG0765	amino acid transport
B1917_RS19360	COG4597	amino acid ABC transporter
B1917_RS19365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B1917_RS19370	COG2884	Cell division ATP-binding protein ftsE
B1917_RS19375	COG2177	Part of the ABC transporter FtsEX involved in
B1917_RS19380	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
B1917_RS19390	COG1194	a g-specific adenine glycosylase
B1917_RS19400	COG2226	methyltransferase
B1917_RS19410	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B1917_RS19415	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B1917_RS19430	COG1024	Enoyl-CoA hydratase
B1917_RS19450	COG1024	Enoyl-CoA hydratase
B1917_RS19455	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B1917_RS19460	COG3181	Tripartite tricarboxylate transporter family receptor
B1917_RS19470	COG0753	catalase activity
B1917_RS19475	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B1917_RS19480	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
B1917_RS19490	COG2175	clavaminate synthase activity
B1917_RS19495	COG1473	amidohydrolase
B1917_RS19500	COG4608	Belongs to the ABC transporter superfamily
B1917_RS19505	COG0444	Belongs to the ABC transporter superfamily
B1917_RS19520	COG0747	negative chemotaxis
B1917_RS19525	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
B1917_RS19560	COG0436	Aminotransferase
B1917_RS19565	COG1278	Cold shock
B1917_RS19585	COG4172	Belongs to the ABC transporter superfamily
B1917_RS19620	COG1596	polysaccharide export
B1917_RS19620	COG1555	photosystem II stabilization