locus-tag	class	description
AV743_RS00005	COG0445	tRNA wobble uridine modification
AV743_RS00010	COG0357	Ribosomal RNA small subunit methyltransferase G
AV743_RS00015	COG1192	Involved in chromosome partitioning
AV743_RS00025	COG1475	DNA binding
AV743_RS00050	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AV743_RS00060	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AV743_RS00070	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AV743_RS00075	COG0081	regulation of translation
AV743_RS00080	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AV743_RS00085	COG0222	ribosome binding
AV743_RS00090	COG0085	RNA polymerase activity
AV743_RS00095	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AV743_RS00135	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AV743_RS00160	COG1024	Enoyl-CoA hydratase
AV743_RS00180	COG0752	glycyl-tRNA synthetase alpha subunit
AV743_RS00185	COG0751	glycine-tRNA ligase activity
AV743_RS00190	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AV743_RS00195	COG0204	Acyl-transferase
AV743_RS00210	COG0242	peptide deformylase activity
AV743_RS00250	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AV743_RS00255	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AV743_RS00255	COG2813	Specifically methylates the guanine in position
AV743_RS00270	COG2223	nitrite transmembrane transporter activity
AV743_RS00275	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AV743_RS00280	COG1794	racemase activity, acting on amino acids and derivatives
AV743_RS00285	COG1126	abc transporter atp-binding protein
AV743_RS00290	COG0765	amino acid transport
AV743_RS00295	COG0765	amino acid transport
AV743_RS00300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AV743_RS00365	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AV743_RS00395	COG0326	Molecular chaperone. Has ATPase activity
AV743_RS00400	COG0625	glutathione transferase activity
AV743_RS00415	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AV743_RS00420	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AV743_RS00430	COG0494	nUDIX hydrolase
AV743_RS00440	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AV743_RS00455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AV743_RS00460	COG0601	transmembrane transport
AV743_RS00465	COG0747	negative chemotaxis
AV743_RS00470	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AV743_RS00490	COG0697	spore germination
AV743_RS00500	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
AV743_RS00505	COG2948	multi-organism process
AV743_RS00510	COG3504	Conjugal transfer protein
AV743_RS00515	COG3736	Type IV secretory pathway, component VirB8
AV743_RS00530	COG3451	type IV secretory pathway VirB4
AV743_RS00535	COG3702	type iv secretory pathway
AV743_RS00570	COG3181	Tripartite tricarboxylate transporter family receptor
AV743_RS00585	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AV743_RS00590	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AV743_RS00595	COG0537	adenosine 5'-monophosphoramidase activity
AV743_RS00600	COG0140	phosphoribosyl-ATP diphosphatase activity
AV743_RS00605	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AV743_RS00610	COG0107	imidazoleglycerol-phosphate synthase activity
AV743_RS00615	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AV743_RS00620	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AV743_RS00625	COG0131	Imidazoleglycerol-phosphate dehydratase
AV743_RS00630	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AV743_RS00635	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AV743_RS00640	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AV743_RS00645	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AV743_RS00655	COG0842	Transport permease protein
AV743_RS00670	COG2853	Lipoprotein
AV743_RS00675	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AV743_RS00680	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AV743_RS00685	COG1127	ABC transporter
AV743_RS00695	COG3047	cAMP biosynthetic process
AV743_RS00705	COG0069	glutamate synthase activity
AV743_RS00705	COG0067	glutamate synthase
AV743_RS00705	COG0070	glutamate synthase
AV743_RS00715	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AV743_RS00720	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AV743_RS00730	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AV743_RS00735	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AV743_RS00755	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AV743_RS00795	COG0109	protoheme IX farnesyltransferase activity
AV743_RS00800	COG1999	signal sequence binding
AV743_RS00820	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AV743_RS00825	COG2814	Major facilitator Superfamily
AV743_RS00915	COG2816	NAD+ diphosphatase activity
AV743_RS00920	COG1309	transcriptional regulator
AV743_RS00925	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AV743_RS00940	COG1024	Enoyl-CoA hydratase
AV743_RS00955	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AV743_RS00970	COG3181	Tripartite tricarboxylate transporter family receptor
AV743_RS01000	COG0438	transferase activity, transferring glycosyl groups
AV743_RS01005	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AV743_RS01010	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AV743_RS01040	COG0859	PFAM glycosyl transferase family 9
AV743_RS01055	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AV743_RS01065	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AV743_RS01070	COG1127	ABC transporter
AV743_RS01100	COG1686	Belongs to the peptidase S11 family
AV743_RS01110	COG2921	Belongs to the UPF0250 family
AV743_RS01115	COG0321	lipoyl(octanoyl) transferase activity
AV743_RS01120	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AV743_RS01155	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AV743_RS01165	COG0018	arginyl-trna synthetase
AV743_RS01190	COG1175	transmembrane transport
AV743_RS01195	COG1653	transport
AV743_RS01200	COG3842	ATPase activity
AV743_RS01205	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AV743_RS01215	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AV743_RS01235	COG1609	Transcriptional regulator
AV743_RS01245	COG0154	amidase activity
AV743_RS01250	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AV743_RS01260	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AV743_RS01270	COG0583	DNA-binding transcription factor activity
AV743_RS01290	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AV743_RS01305	COG1802	Transcriptional regulator
AV743_RS01320	COG1024	Enoyl-CoA hydratase
AV743_RS01335	COG3181	Tripartite tricarboxylate transporter family receptor
AV743_RS01350	COG1984	allophanate hydrolase subunit 2
AV743_RS01355	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AV743_RS01365	COG0583	DNA-binding transcription factor activity
AV743_RS01370	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AV743_RS01380	COG5002	protein histidine kinase activity
AV743_RS01390	COG5002	protein histidine kinase activity
AV743_RS01395	COG0745	RESPONSE REGULATOR receiver
AV743_RS01400	COG2226	methyltransferase
AV743_RS01415	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AV743_RS01435	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AV743_RS01445	COG0513	Belongs to the DEAD box helicase family
AV743_RS01450	COG1280	lysine exporter protein (LysE YggA)
AV743_RS01455	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AV743_RS01500	COG1054	Belongs to the UPF0176 family
AV743_RS01505	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AV743_RS01505	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AV743_RS01515	COG0489	protein tyrosine kinase activity
AV743_RS01530	COG0717	Belongs to the dCTP deaminase family
AV743_RS01560	COG2081	HI0933 family
AV743_RS01570	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AV743_RS01580	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AV743_RS01585	COG0509	glycine decarboxylation via glycine cleavage system
AV743_RS01590	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AV743_RS01590	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AV743_RS01655	COG1304	FMN binding
AV743_RS01670	COG0154	amidase activity
AV743_RS01675	COG1414	Transcriptional regulator
AV743_RS01690	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AV743_RS01695	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AV743_RS01700	COG0594	ribonuclease P activity
AV743_RS01705	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AV743_RS01710	COG0706	membrane insertase activity
AV743_RS01745	COG0582	viral genome integration into host DNA
AV743_RS01780	COG3723	Recombinational DNA repair protein, rece pathway
AV743_RS01885	COG1024	Enoyl-CoA hydratase
AV743_RS01890	COG1960	acyl-CoA dehydrogenase activity
AV743_RS01915	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AV743_RS01920	COG0352	thiamine-phosphate diphosphorylase activity
AV743_RS01935	COG1678	Uncharacterized ACR, COG1678
AV743_RS01940	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AV743_RS01945	COG0540	Belongs to the ATCase OTCase family
AV743_RS01960	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AV743_RS01970	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AV743_RS02005	COG1234	tRNA 3'-trailer cleavage
AV743_RS02020	COG3064	Membrane
AV743_RS02050	COG1683	Conserved Protein
AV743_RS02055	COG1120	ATPase activity
AV743_RS02060	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AV743_RS02065	COG4558	Periplasmic binding protein
AV743_RS02070	COG3720	iron ion transport
AV743_RS02080	COG3712	iron ion homeostasis
AV743_RS02085	COG1595	DNA-templated transcription, initiation
AV743_RS02110	COG2423	ornithine cyclodeaminase activity
AV743_RS02120	COG1802	Transcriptional regulator
AV743_RS02130	COG3069	C4-dicarboxylate transmembrane transporter activity
AV743_RS02140	COG1012	belongs to the aldehyde dehydrogenase family
AV743_RS02180	COG2860	membrane
AV743_RS02185	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AV743_RS02190	COG0708	Exodeoxyribonuclease III
AV743_RS02195	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AV743_RS02200	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AV743_RS02205	COG0154	amidase activity
AV743_RS02210	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AV743_RS02215	COG1077	Cell shape determining protein MreB Mrl
AV743_RS02220	COG1792	Involved in formation and maintenance of cell shape
AV743_RS02230	COG0768	penicillin binding
AV743_RS02235	COG0772	Belongs to the SEDS family
AV743_RS02240	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AV743_RS02245	COG0471	metal ion transport
AV743_RS02250	COG1309	transcriptional regulator
AV743_RS02260	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AV743_RS02275	COG2823	Periplasmic or secreted lipoprotein
AV743_RS02280	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AV743_RS02295	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AV743_RS02315	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AV743_RS02325	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AV743_RS02345	COG0492	ferredoxin-NADP+ reductase activity
AV743_RS02355	COG3181	Tripartite tricarboxylate transporter family receptor
AV743_RS02360	COG1250	3-hydroxyacyl-CoA dehydrogenase
AV743_RS02360	COG1024	Enoyl-CoA hydratase
AV743_RS02365	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AV743_RS02370	COG0028	Belongs to the TPP enzyme family
AV743_RS02395	COG3181	Tripartite tricarboxylate transporter family receptor
AV743_RS02410	COG0697	spore germination
AV743_RS02440	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AV743_RS02445	COG0463	Glycosyl transferase, family 2
AV743_RS02460	COG0786	glutamate:sodium symporter activity
AV743_RS02470	COG2031	fatty acid transporter
AV743_RS02485	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AV743_RS02500	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AV743_RS02515	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AV743_RS02525	COG1285	pathogenesis
AV743_RS02530	COG1253	flavin adenine dinucleotide binding
AV743_RS02535	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AV743_RS02540	COG1024	Enoyl-CoA hydratase
AV743_RS02545	COG3181	Tripartite tricarboxylate transporter family receptor
AV743_RS02550	COG0583	DNA-binding transcription factor activity
AV743_RS02555	COG1960	acyl-CoA dehydrogenase activity
AV743_RS02585	COG0583	DNA-binding transcription factor activity
AV743_RS02590	COG1278	Cold shock
AV743_RS02600	COG1802	Transcriptional regulator
AV743_RS02605	COG1012	belongs to the aldehyde dehydrogenase family
AV743_RS02610	COG2031	fatty acid transporter
AV743_RS02615	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AV743_RS02615	COG1017	nitric oxide dioxygenase activity
AV743_RS02620	COG0251	oxidation-reduction process
AV743_RS02640	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AV743_RS02650	COG0583	DNA-binding transcription factor activity
AV743_RS02655	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AV743_RS02670	COG0028	Belongs to the TPP enzyme family
AV743_RS02690	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AV743_RS02700	COG0318	PFAM AMP-dependent synthetase and ligase
AV743_RS02710	COG1802	Transcriptional regulator
AV743_RS02720	COG1802	Transcriptional regulator
AV743_RS02730	COG1028	Short-chain dehydrogenase reductase Sdr
AV743_RS02750	COG1126	abc transporter atp-binding protein
AV743_RS02755	COG0765	amino acid transport
AV743_RS02775	COG1538	Outer membrane efflux protein
AV743_RS02780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AV743_RS02785	COG2274	protein secretion by the type I secretion system
AV743_RS02790	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
AV743_RS02800	COG2994	toxin metabolic process
AV743_RS02815	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AV743_RS02820	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
AV743_RS02830	COG0583	DNA-binding transcription factor activity
AV743_RS02840	COG0142	geranyltranstransferase activity
AV743_RS02850	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AV743_RS02855	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AV743_RS02860	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AV743_RS02865	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AV743_RS02910	COG3712	iron ion homeostasis
AV743_RS02915	COG4774	siderophore transport
AV743_RS02920	COG2353	YceI-like domain
AV743_RS02935	COG0019	diaminopimelate decarboxylase activity
AV743_RS02960	COG0601	transmembrane transport
AV743_RS02965	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AV743_RS02975	COG0154	amidase activity
AV743_RS02980	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AV743_RS03005	COG2154	pterin-4-alpha-carbinolamine dehydratase
AV743_RS03015	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AV743_RS03025	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AV743_RS03030	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AV743_RS03035	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AV743_RS03040	COG1929	Belongs to the glycerate kinase type-1 family
AV743_RS03045	COG0469	pyruvate kinase activity
AV743_RS03050	COG0700	Nucleoside recognition
AV743_RS03105	COG1024	Enoyl-CoA hydratase
AV743_RS03110	COG1024	Enoyl-CoA hydratase
AV743_RS03115	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AV743_RS03135	COG0601	transmembrane transport
AV743_RS03140	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AV743_RS03145	COG4172	Belongs to the ABC transporter superfamily
AV743_RS03155	COG2195	Cleaves the N-terminal amino acid of tripeptides
AV743_RS03165	COG0210	DNA helicase
AV743_RS03170	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AV743_RS03175	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AV743_RS03185	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AV743_RS03190	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AV743_RS03195	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AV743_RS03200	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AV743_RS03205	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AV743_RS03210	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AV743_RS03220	COG0356	it plays a direct role in the translocation of protons across the membrane
AV743_RS03245	COG1024	Enoyl-CoA hydratase
AV743_RS03250	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AV743_RS03255	COG3634	alkyl hydroperoxide reductase activity
AV743_RS03265	COG0037	tRNA processing
AV743_RS03275	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AV743_RS03280	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AV743_RS03285	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AV743_RS03290	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AV743_RS03295	COG2967	ApaG domain
AV743_RS03300	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AV743_RS03305	COG0546	phosphoglycolate phosphatase activity
AV743_RS03315	COG0512	Glutamine amidotransferase of anthranilate synthase
AV743_RS03320	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AV743_RS03325	COG0134	indole-3-glycerol-phosphate synthase activity
AV743_RS03350	COG0583	DNA-binding transcription factor activity
AV743_RS03365	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AV743_RS03370	COG0259	pyridoxamine-phosphate oxidase activity
AV743_RS03380	COG2814	Major facilitator Superfamily
AV743_RS03385	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AV743_RS03390	COG2188	Transcriptional regulator
AV743_RS03395	COG0318	PFAM AMP-dependent synthetase and ligase
AV743_RS03415	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AV743_RS03425	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AV743_RS03440	COG1215	transferase activity, transferring glycosyl groups
AV743_RS03450	COG0601	transmembrane transport
AV743_RS03485	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AV743_RS03490	COG2894	cell division
AV743_RS03495	COG0850	regulation of cytokinetic process
AV743_RS03500	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AV743_RS03505	COG1271	oxidase subunit
AV743_RS03540	COG2979	Protein of unknown function (DUF533)
AV743_RS03560	COG1388	LysM domain
AV743_RS03560	COG0741	lytic transglycosylase activity
AV743_RS03565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AV743_RS03570	COG2226	methyltransferase
AV743_RS03575	COG0328	RNA-DNA hybrid ribonuclease activity
AV743_RS03625	COG2030	dehydratase
AV743_RS03675	COG1960	acyl-CoA dehydrogenase activity
AV743_RS03690	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AV743_RS03710	COG2718	Belongs to the UPF0229 family
AV743_RS03715	COG2719	SpoVR family
AV743_RS03740	COG2188	Transcriptional regulator
AV743_RS03765	COG0829	nickel cation binding
AV743_RS03770	COG0831	urea catabolic process
AV743_RS03780	COG0832	Belongs to the urease beta subunit family
AV743_RS03785	COG0804	urea catabolic process
AV743_RS03795	COG0830	nickel cation binding
AV743_RS03800	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AV743_RS03820	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AV743_RS03840	COG0747	negative chemotaxis
AV743_RS03850	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AV743_RS03855	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AV743_RS03865	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AV743_RS03875	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
AV743_RS03880	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AV743_RS03885	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AV743_RS03900	COG0438	transferase activity, transferring glycosyl groups
AV743_RS03915	COG0438	transferase activity, transferring glycosyl groups
AV743_RS03920	COG0438	transferase activity, transferring glycosyl groups
AV743_RS03925	COG0166	Belongs to the GPI family
AV743_RS03940	COG0277	FAD linked oxidase domain protein
AV743_RS03945	COG0745	RESPONSE REGULATOR receiver
AV743_RS03950	COG0642	Histidine kinase
AV743_RS03955	COG1368	sulfuric ester hydrolase activity
AV743_RS03965	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AV743_RS03990	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AV743_RS04000	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AV743_RS04005	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AV743_RS04015	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AV743_RS04020	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AV743_RS04025	COG0193	aminoacyl-tRNA hydrolase activity
AV743_RS04035	COG0012	GTP binding
AV743_RS04040	COG0582	viral genome integration into host DNA
AV743_RS04065	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AV743_RS04125	COG0745	RESPONSE REGULATOR receiver
AV743_RS04140	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AV743_RS04145	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AV743_RS04200	COG2096	Adenosyltransferase
AV743_RS04215	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AV743_RS04220	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AV743_RS04230	COG0523	cobalamin synthesis protein
AV743_RS04235	COG0735	belongs to the Fur family
AV743_RS04255	COG0803	Belongs to the bacterial solute-binding protein 9 family
AV743_RS04265	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
AV743_RS04275	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AV743_RS04285	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AV743_RS04290	COG1560	Kdo2-lipid A biosynthetic process
AV743_RS04300	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AV743_RS04315	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AV743_RS04320	COG1950	PFAM Membrane protein of
AV743_RS04340	COG0583	DNA-binding transcription factor activity
AV743_RS04350	COG0477	Major facilitator Superfamily
AV743_RS04365	COG0617	tRNA 3'-terminal CCA addition
AV743_RS04375	COG0513	Belongs to the DEAD box helicase family
AV743_RS04380	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AV743_RS04400	COG2084	Dehydrogenase
AV743_RS04435	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AV743_RS04440	COG0129	dihydroxy-acid dehydratase activity
AV743_RS04445	COG4654	Cytochrome c, class I
AV743_RS04450	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AV743_RS04500	COG1473	amidohydrolase
AV743_RS04505	COG0418	dihydroorotase activity
AV743_RS04510	COG0488	(ABC) transporter
AV743_RS04520	COG2001	Belongs to the MraZ family
AV743_RS04525	COG0275	rRNA processing
AV743_RS04530	COG3116	cell division
AV743_RS04540	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AV743_RS04545	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AV743_RS04550	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AV743_RS04560	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AV743_RS04565	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AV743_RS04570	COG1181	Belongs to the D-alanine--D-alanine ligase family
AV743_RS04575	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AV743_RS04585	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AV743_RS04590	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AV743_RS04600	COG0739	heme binding
AV743_RS04605	COG0653	protein targeting
AV743_RS04625	COG1028	Short-chain dehydrogenase reductase Sdr
AV743_RS04630	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AV743_RS04635	COG1522	sequence-specific DNA binding
AV743_RS04660	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AV743_RS04670	COG0557	exoribonuclease II activity
AV743_RS04675	COG3150	esterase
AV743_RS04680	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AV743_RS04685	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AV743_RS04690	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AV743_RS04695	COG0511	ligase activity, forming carbon-carbon bonds
AV743_RS04700	COG0439	Biotin carboxylase
AV743_RS04715	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AV743_RS04740	COG1696	Membrane protein involved in D-alanine export
AV743_RS04745	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AV743_RS04780	COG1522	sequence-specific DNA binding
AV743_RS04795	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AV743_RS04800	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AV743_RS04800	COG1042	CoA-binding domain protein
AV743_RS04800	COG0045	succinate-CoA ligase (ADP-forming) activity
AV743_RS04815	COG1802	Transcriptional regulator
AV743_RS04820	COG3069	C4-dicarboxylate transmembrane transporter activity
AV743_RS04825	COG0513	Belongs to the DEAD box helicase family
AV743_RS04830	COG0346	lactoylglutathione lyase activity
AV743_RS04835	COG1335	isochorismatase
AV743_RS04840	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AV743_RS04845	COG1116	anion transmembrane transporter activity
AV743_RS04860	COG3028	Belongs to the UPF0307 family
AV743_RS04865	COG0312	modulator of DNA gyrase
AV743_RS04870	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AV743_RS04875	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AV743_RS04880	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AV743_RS04885	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AV743_RS04895	COG0316	Belongs to the HesB IscA family
AV743_RS04900	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AV743_RS04915	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AV743_RS04925	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AV743_RS04930	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AV743_RS04945	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AV743_RS04945	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AV743_RS04980	COG0583	DNA-binding transcription factor activity
AV743_RS04985	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AV743_RS05020	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
AV743_RS05030	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AV743_RS05035	COG1845	cytochrome c oxidase, subunit III
AV743_RS05040	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AV743_RS05045	COG0640	Transcriptional regulator
AV743_RS05065	COG3220	belongs to the UPF0276 family
AV743_RS05110	COG1666	GTP binding
AV743_RS05145	COG0312	modulator of DNA gyrase
AV743_RS05150	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AV743_RS05155	COG3064	Membrane
AV743_RS05155	COG3210	domain, Protein
AV743_RS05155	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
AV743_RS05155	COG3064	Membrane
AV743_RS05155	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
AV743_RS05155	COG3210	domain, Protein
AV743_RS05160	COG0277	FAD linked oxidase domain protein
AV743_RS05165	COG0277	FAD linked oxidase domain protein
AV743_RS05170	COG0277	FAD linked oxidase domain protein
AV743_RS05175	COG0247	lactate metabolic process
AV743_RS05180	COG2819	hydrolase of the alpha beta superfamily
AV743_RS05220	COG0583	DNA-binding transcription factor activity
AV743_RS05225	COG0482	sulfurtransferase activity
AV743_RS05230	COG0730	response to heat
AV743_RS05235	COG0625	glutathione transferase activity
AV743_RS05240	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AV743_RS05245	COG3909	cytochrome
AV743_RS05285	COG0154	amidase activity
AV743_RS05290	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AV743_RS05295	COG1024	Enoyl-CoA hydratase
AV743_RS05310	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AV743_RS05325	COG1028	Short-chain dehydrogenase reductase Sdr
AV743_RS05330	COG1414	Transcriptional regulator
AV743_RS05340	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AV743_RS05345	COG0251	oxidation-reduction process
AV743_RS05350	COG0559	Belongs to the binding-protein-dependent transport system permease family
AV743_RS05385	COG0583	DNA-binding transcription factor activity
AV743_RS05395	COG0590	tRNA wobble adenosine to inosine editing
AV743_RS05400	COG2807	transmembrane transport
AV743_RS05420	COG0154	amidase activity
AV743_RS05425	COG0307	riboflavin synthase, alpha
AV743_RS05430	COG3181	Tripartite tricarboxylate transporter family receptor
AV743_RS05435	COG1522	sequence-specific DNA binding
AV743_RS05445	COG0318	PFAM AMP-dependent synthetase and ligase
AV743_RS05455	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AV743_RS05475	COG1063	alcohol dehydrogenase
AV743_RS05500	COG1418	mRNA catabolic process
AV743_RS05505	COG1448	Aminotransferase
AV743_RS05510	COG0583	DNA-binding transcription factor activity
AV743_RS05520	COG0477	Major facilitator Superfamily
AV743_RS05525	COG1028	Short-chain dehydrogenase reductase Sdr
AV743_RS05540	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AV743_RS05545	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AV743_RS05550	COG0583	DNA-binding transcription factor activity
AV743_RS05610	COG1028	Short-chain dehydrogenase reductase Sdr
AV743_RS05615	COG1309	transcriptional regulator
AV743_RS05620	COG2982	Protein involved in outer membrane biogenesis
AV743_RS05625	COG2818	Glycosylase
AV743_RS05645	COG1653	transport
AV743_RS05660	COG3842	ATPase activity
AV743_RS05665	COG0395	ABC-type sugar transport system, permease component
AV743_RS05670	COG1175	transmembrane transport
AV743_RS05685	COG3181	Tripartite tricarboxylate transporter family receptor
AV743_RS05690	COG2186	Transcriptional regulator
AV743_RS05720	COG1454	alcohol dehydrogenase
AV743_RS05740	COG2011	ABC-type metal ion transport system permease component
AV743_RS05745	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AV743_RS05750	COG1501	Belongs to the glycosyl hydrolase 31 family
AV743_RS05775	COG0318	PFAM AMP-dependent synthetase and ligase
AV743_RS05780	COG1473	amidohydrolase
AV743_RS05790	COG2855	membrane
AV743_RS05800	COG2239	Acts as a magnesium transporter
AV743_RS05820	COG3181	Tripartite tricarboxylate transporter family receptor
AV743_RS05830	COG1722	exodeoxyribonuclease VII activity
AV743_RS05835	COG0142	geranyltranstransferase activity
AV743_RS05840	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AV743_RS05845	COG1469	GTP cyclohydrolase I activity
AV743_RS05850	COG0360	Binds together with S18 to 16S ribosomal RNA
AV743_RS05855	COG2965	DNA replication, synthesis of RNA primer
AV743_RS05860	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AV743_RS05865	COG0359	binds to the 23S rRNA
AV743_RS05875	COG0305	Participates in initiation and elongation during chromosome replication
AV743_RS05885	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AV743_RS05890	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AV743_RS05895	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AV743_RS05900	COG3737	Protein of unknown function (DUF498/DUF598)
AV743_RS05905	COG0436	Aminotransferase
AV743_RS05930	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AV743_RS05965	COG0268	Binds directly to 16S ribosomal RNA
AV743_RS05975	COG0728	peptidoglycan biosynthetic process
AV743_RS05985	COG0563	adenylate kinase activity
AV743_RS05990	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AV743_RS05995	COG2835	tetraacyldisaccharide 4'-kinase activity
AV743_RS06000	COG1663	tetraacyldisaccharide 4'-kinase activity
AV743_RS06005	COG0848	biopolymer transport protein
AV743_RS06010	COG0811	peptide transport
AV743_RS06020	COG1570	exodeoxyribonuclease VII activity
AV743_RS06025	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AV743_RS06030	COG0038	chloride channel
AV743_RS06035	COG0183	Belongs to the thiolase family
AV743_RS06045	COG1278	Cold shock
AV743_RS06050	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AV743_RS06060	COG4953	penicillin-binding protein 1C
AV743_RS06065	COG0542	response to heat
AV743_RS06070	COG2995	paraquat-inducible protein a
AV743_RS06075	COG3008	intermembrane lipid transfer
AV743_RS06075	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AV743_RS06085	COG0506	proline dehydrogenase activity
AV743_RS06085	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AV743_RS06085	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AV743_RS06120	COG2271	Major facilitator Superfamily
AV743_RS06125	COG1309	transcriptional regulator
AV743_RS06170	COG0477	Major facilitator Superfamily
AV743_RS06180	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AV743_RS06185	COG1845	cytochrome c oxidase, subunit III
AV743_RS06190	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AV743_RS06200	COG1028	Short-chain dehydrogenase reductase Sdr
AV743_RS06220	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AV743_RS06225	COG0303	'Molybdopterin
AV743_RS06230	COG0521	Mo-molybdopterin cofactor biosynthetic process
AV743_RS06245	COG0315	cyclic pyranopterin monophosphate synthase activity
AV743_RS06255	COG0412	Dienelactone hydrolase
AV743_RS06265	COG0678	peroxiredoxin activity
AV743_RS06275	COG0697	spore germination
AV743_RS06280	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AV743_RS06305	COG0789	Transcriptional regulator
AV743_RS06320	COG3468	outer membrane autotransporter barrel domain protein
AV743_RS06330	COG5441	Belongs to the UPF0261 family
AV743_RS06335	COG5564	TIM-barrel signal transduction protein
AV743_RS06350	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AV743_RS06365	COG1477	protein flavinylation
AV743_RS06385	COG1131	(ABC) transporter
AV743_RS06390	COG0842	Transport permease protein
AV743_RS06400	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AV743_RS06405	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
AV743_RS06405	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
AV743_RS06410	COG1562	ergosterol biosynthetic process
AV743_RS06415	COG1562	ergosterol biosynthetic process
AV743_RS06420	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AV743_RS06425	COG1028	Short-chain dehydrogenase reductase Sdr
AV743_RS06445	COG2304	oxidoreductase activity
AV743_RS06465	COG0534	Mate efflux family protein
AV743_RS06475	COG0254	rRNA binding
AV743_RS06480	COG3483	tryptophan 2,3-dioxygenase activity
AV743_RS06485	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AV743_RS06490	COG2003	Belongs to the UPF0758 family
AV743_RS06495	COG1047	Peptidyl-prolyl cis-trans
AV743_RS06500	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AV743_RS06505	COG0625	glutathione transferase activity
AV743_RS06525	COG0523	cobalamin synthesis protein
AV743_RS06535	COG0583	DNA-binding transcription factor activity
AV743_RS06545	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AV743_RS06550	COG1187	pseudouridine synthase activity
AV743_RS06555	COG0779	Required for maturation of 30S ribosomal subunits
AV743_RS06560	COG0195	Participates in both transcription termination and antitermination
AV743_RS06560	COG2251	uridine kinase activity
AV743_RS06565	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AV743_RS06570	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AV743_RS06575	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AV743_RS06595	COG1611	Belongs to the LOG family
AV743_RS06610	COG0412	Dienelactone hydrolase
AV743_RS06615	COG1283	sodium-dependent phosphate transmembrane transporter activity
AV743_RS06620	COG1760	l-serine dehydratase
AV743_RS06625	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AV743_RS06630	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AV743_RS06640	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AV743_RS06665	COG2311	Membrane
AV743_RS06685	COG3842	ATPase activity
AV743_RS06690	COG0395	ABC-type sugar transport system, permease component
AV743_RS06695	COG1175	transmembrane transport
AV743_RS06700	COG1653	transport
AV743_RS06710	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AV743_RS06725	COG0559	Belongs to the binding-protein-dependent transport system permease family
AV743_RS06745	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AV743_RS06775	COG2363	Small membrane protein
AV743_RS06790	COG1464	Belongs to the NlpA lipoprotein family
AV743_RS06800	COG0688	phosphatidylethanolamine metabolic process
AV743_RS06815	COG0095	Lipoate-protein ligase
AV743_RS06830	COG0625	glutathione transferase activity
AV743_RS06835	COG0386	Belongs to the glutathione peroxidase family
AV743_RS06855	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AV743_RS06885	COG2259	Doxx family
AV743_RS06900	COG0667	Aldo Keto reductase
AV743_RS06930	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AV743_RS06950	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AV743_RS06960	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AV743_RS07010	COG0210	DNA helicase
AV743_RS07015	COG0598	Magnesium transport protein CorA
AV743_RS07025	COG0747	negative chemotaxis
AV743_RS07030	COG0601	transmembrane transport
AV743_RS07035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AV743_RS07040	COG4172	Belongs to the ABC transporter superfamily
AV743_RS07045	COG1846	Transcriptional regulator
AV743_RS07090	COG4964	Belongs to the GSP D family
AV743_RS07130	COG2204	response regulator
AV743_RS07145	COG1595	DNA-templated transcription, initiation
AV743_RS07155	COG3474	cytochrome
AV743_RS07160	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AV743_RS07175	COG3384	dioxygenase
AV743_RS07180	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AV743_RS07210	COG2885	chlorophyll binding
AV743_RS07245	COG0697	spore germination
AV743_RS07250	COG0730	response to heat
AV743_RS07270	COG0583	DNA-binding transcription factor activity
AV743_RS07275	COG0427	acetyl-CoA hydrolase
AV743_RS07320	COG3468	outer membrane autotransporter barrel domain protein
AV743_RS07325	COG0424	maF-like protein
AV743_RS07330	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AV743_RS07335	COG0799	negative regulation of ribosome biogenesis
AV743_RS07340	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AV743_RS07345	COG0408	coproporphyrinogen oxidase activity
AV743_RS07350	COG0151	Belongs to the GarS family
AV743_RS07355	COG0217	transcriptional regulatory protein
AV743_RS07360	COG0433	COG0433 Predicted ATPase
AV743_RS07365	COG1115	amino acid carrier protein
AV743_RS07370	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AV743_RS07380	COG1012	belongs to the aldehyde dehydrogenase family
AV743_RS07405	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AV743_RS07420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AV743_RS07430	COG0747	negative chemotaxis
AV743_RS07440	COG0473	3-isopropylmalate dehydrogenase activity
AV743_RS07445	COG2814	Major facilitator Superfamily
AV743_RS07450	COG1566	PFAM secretion protein HlyD family protein
AV743_RS07460	COG1846	Transcriptional regulator
AV743_RS07470	COG0697	spore germination
AV743_RS07480	COG0501	Belongs to the peptidase M48B family
AV743_RS07500	COG0583	DNA-binding transcription factor activity
AV743_RS07505	COG3842	ATPase activity
AV743_RS07510	COG1178	ABC-type Fe3 transport system permease component
AV743_RS07515	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AV743_RS07520	COG1840	ABC-type Fe3 transport system, periplasmic component
AV743_RS07550	COG2233	PERMEase
AV743_RS07555	COG0840	transmembrane signaling receptor activity
AV743_RS07560	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AV743_RS07590	COG4789	Type iii secretion
AV743_RS07655	COG4669	(LipO)protein
AV743_RS07690	COG4790	Type iii secretion
AV743_RS07695	COG4794	Type iii secretion
AV743_RS07700	COG4791	protein targeting
AV743_RS07705	COG4792	protein secretion
AV743_RS07720	COG1595	DNA-templated transcription, initiation
AV743_RS07740	COG2770	Histidine kinase
AV743_RS07740	COG2208	phosphoserine phosphatase activity
AV743_RS07750	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AV743_RS07755	COG2172	sigma factor antagonist activity
AV743_RS07760	COG1366	Belongs to the anti-sigma-factor antagonist family
AV743_RS07765	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AV743_RS07800	COG2358	TRAP transporter, solute receptor (TAXI family
AV743_RS07805	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AV743_RS07835	COG1017	nitric oxide dioxygenase activity
AV743_RS07835	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AV743_RS07840	COG1959	2 iron, 2 sulfur cluster binding
AV743_RS07845	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AV743_RS07865	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AV743_RS07870	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AV743_RS07875	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AV743_RS07880	COG0084	hydrolase, TatD family'
AV743_RS07895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AV743_RS07905	COG1126	abc transporter atp-binding protein
AV743_RS07915	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AV743_RS07930	COG0028	Belongs to the TPP enzyme family
AV743_RS07940	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AV743_RS07940	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AV743_RS07950	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AV743_RS08000	COG4336	lyase activity
AV743_RS08010	COG2205	protein histidine kinase activity
AV743_RS08010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AV743_RS08015	COG2197	response regulator
AV743_RS08045	COG3121	Chaperone
AV743_RS08050	COG3188	usher protein
AV743_RS08055	COG3539	Fimbrial protein
AV743_RS08060	COG2831	hemolysin activation secretion protein
AV743_RS08075	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AV743_RS08135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AV743_RS08140	COG0765	amino acid transport
AV743_RS08145	COG1126	abc transporter atp-binding protein
AV743_RS08150	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AV743_RS08155	COG1758	RNA polymerase activity
AV743_RS08160	COG0194	GDP metabolic process
AV743_RS08165	COG3258	Cytochrome c
AV743_RS08170	COG2863	cytochrome
AV743_RS08175	COG1028	Short-chain dehydrogenase reductase Sdr
AV743_RS08180	COG0791	NLP P60 protein
AV743_RS08185	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AV743_RS08205	COG1561	YicC-like family, N-terminal region
AV743_RS08210	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AV743_RS08225	COG0840	transmembrane signaling receptor activity
AV743_RS08230	COG2199	diguanylate cyclase activity
AV743_RS08230	COG2200	EAL domain
AV743_RS08235	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AV743_RS08250	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AV743_RS08255	COG0174	glutamine synthetase
AV743_RS08265	COG2204	response regulator
AV743_RS08270	COG0583	DNA-binding transcription factor activity
AV743_RS08275	COG1741	Belongs to the pirin family
AV743_RS08280	COG1741	Belongs to the pirin family
AV743_RS08285	COG3842	ATPase activity
AV743_RS08290	COG1178	ABC-type Fe3 transport system permease component
AV743_RS08295	COG1840	ABC-type Fe3 transport system, periplasmic component
AV743_RS08305	COG0583	DNA-binding transcription factor activity
AV743_RS08315	COG0656	L-ascorbic acid biosynthetic process
AV743_RS08330	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AV743_RS08335	COG0583	DNA-binding transcription factor activity
AV743_RS08350	COG0783	Belongs to the Dps family
AV743_RS08370	COG0463	Glycosyl transferase, family 2
AV743_RS08390	COG0438	transferase activity, transferring glycosyl groups
AV743_RS08405	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AV743_RS08425	COG0300	oxidoreductase activity
AV743_RS08470	COG0861	Integral membrane protein TerC family
AV743_RS08475	COG1028	Short-chain dehydrogenase reductase Sdr
AV743_RS08495	COG0714	Associated with various cellular activities
AV743_RS08530	COG3119	arylsulfatase activity
AV743_RS08550	COG0431	NADPH-dependent FMN reductase
AV743_RS08580	COG1028	Short-chain dehydrogenase reductase Sdr
AV743_RS08585	COG0583	DNA-binding transcription factor activity
AV743_RS08605	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AV743_RS08605	COG2111	Na H antiporter
AV743_RS08610	COG1006	Multisubunit Na H antiporter MnhC subunit
AV743_RS08615	COG0651	ATP synthesis coupled electron transport
AV743_RS08620	COG1863	multisubunit Na H antiporter MnhE subunit
AV743_RS08625	COG2212	antiporter activity
AV743_RS08655	COG0590	tRNA wobble adenosine to inosine editing
AV743_RS08660	COG1619	proteins homologs of microcin C7 resistance protein MccF
AV743_RS08665	COG1024	Enoyl-CoA hydratase
AV743_RS08680	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AV743_RS08685	COG0488	(ABC) transporter
AV743_RS08720	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AV743_RS08730	COG2252	PERMEase
AV743_RS08735	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AV743_RS08745	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AV743_RS08750	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AV743_RS08780	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AV743_RS08785	COG0789	Transcriptional regulator
AV743_RS08795	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AV743_RS08795	COG0678	peroxiredoxin activity
AV743_RS08805	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AV743_RS08810	COG0584	glycerophosphoryl diester phosphodiesterase
AV743_RS08815	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AV743_RS08825	COG4181	ATPase activity
AV743_RS08840	COG2823	Periplasmic or secreted lipoprotein
AV743_RS08850	COG3237	CsbD-like
AV743_RS08855	COG1181	Belongs to the D-alanine--D-alanine ligase family
AV743_RS08855	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AV743_RS08860	COG0189	ligase activity
AV743_RS08860	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AV743_RS08880	COG2833	Protein of unknown function (DUF455)
AV743_RS08885	COG2951	lytic endotransglycosylase activity
AV743_RS08905	COG1522	sequence-specific DNA binding
AV743_RS08915	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AV743_RS08920	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AV743_RS08925	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AV743_RS08930	COG0196	riboflavin kinase activity
AV743_RS08935	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AV743_RS08955	COG0210	DNA helicase
AV743_RS08960	COG4771	TonB-dependent receptor
AV743_RS08965	COG0488	(ABC) transporter
AV743_RS08970	COG2890	protein-(glutamine-N5) methyltransferase activity
AV743_RS08975	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AV743_RS08980	COG2171	N-acyltransferase activity
AV743_RS09015	COG1278	Cold shock
AV743_RS09025	COG1278	Cold shock
AV743_RS09035	COG0544	peptidyl-prolyl cis-trans isomerase activity
AV743_RS09040	COG0740	serine-type endopeptidase activity
AV743_RS09045	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AV743_RS09050	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AV743_RS09055	COG0583	DNA-binding transcription factor activity
AV743_RS09060	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AV743_RS09085	COG0183	Belongs to the thiolase family
AV743_RS09090	COG1028	Short-chain dehydrogenase reductase Sdr
AV743_RS09110	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AV743_RS09140	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AV743_RS09150	COG0556	nucleotide-excision repair
AV743_RS09155	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AV743_RS09165	COG1104	cysteine desulfurase activity
AV743_RS09170	COG0822	iron-sulfur transferase activity
AV743_RS09175	COG0316	Belongs to the HesB IscA family
AV743_RS09180	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AV743_RS09185	COG0443	Heat shock 70 kDa protein
AV743_RS09190	COG0633	Ferredoxin
AV743_RS09210	COG1024	Enoyl-CoA hydratase
AV743_RS09225	COG3395	kinase activity
AV743_RS09245	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AV743_RS09255	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AV743_RS09280	COG0747	negative chemotaxis
AV743_RS09285	COG0601	transmembrane transport
AV743_RS09290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AV743_RS09295	COG4172	Belongs to the ABC transporter superfamily
AV743_RS09300	COG0154	amidase activity
AV743_RS09345	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AV743_RS09350	COG0425	Belongs to the sulfur carrier protein TusA family
AV743_RS09360	COG0228	four-way junction DNA binding
AV743_RS09365	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AV743_RS09370	COG0336	Belongs to the RNA methyltransferase TrmD family
AV743_RS09375	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AV743_RS09395	COG0642	Histidine kinase
AV743_RS09410	COG0525	valine-tRNA ligase activity
AV743_RS09415	COG0105	UTP biosynthetic process
AV743_RS09420	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AV743_RS09430	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AV743_RS09435	COG0124	histidyl-tRNA synthetase
AV743_RS09440	COG2976	Protein conserved in bacteria
AV743_RS09445	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AV743_RS09450	COG1160	GTP binding
AV743_RS09455	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AV743_RS09460	COG1923	regulation of RNA biosynthetic process
AV743_RS09465	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AV743_RS09470	COG0330	HflC and HflK could
AV743_RS09475	COG0330	HflC and HflK could
AV743_RS09480	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AV743_RS09485	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AV743_RS09490	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AV743_RS09495	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AV743_RS09505	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AV743_RS09535	COG0628	permease
AV743_RS09540	COG0842	Transport permease protein
AV743_RS09545	COG1131	(ABC) transporter
AV743_RS09615	COG0156	8-amino-7-oxononanoate synthase activity
AV743_RS09625	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AV743_RS09625	COG4106	trans-aconitate 2-methyltransferase activity
AV743_RS09630	COG1380	Effector of murein hydrolase LrgA
AV743_RS09660	COG3284	Transcriptional regulator
AV743_RS09665	COG1012	belongs to the aldehyde dehydrogenase family
AV743_RS09680	COG2733	membrane
AV743_RS09685	COG0583	DNA-binding transcription factor activity
AV743_RS09690	COG0384	phenazine biosynthesis protein PhzF
AV743_RS09695	COG5507	3-demethylubiquinone-9 3-methyltransferase
AV743_RS09700	COG2169	Transcriptional regulator
AV743_RS09730	COG0659	secondary active sulfate transmembrane transporter activity
AV743_RS09785	COG2207	Transcriptional regulator
AV743_RS09915	COG2346	COG2346, Truncated hemoglobins
AV743_RS09945	COG0583	DNA-binding transcription factor activity
AV743_RS09960	COG0183	Belongs to the thiolase family
AV743_RS09975	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AV743_RS09980	COG0633	Ferredoxin
AV743_RS09990	COG1024	Enoyl-CoA hydratase
AV743_RS10000	COG4638	Rieske (2fe-2S)
AV743_RS10010	COG0559	Belongs to the binding-protein-dependent transport system permease family
AV743_RS10030	COG2224	Isocitrate lyase
AV743_RS10035	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AV743_RS10035	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AV743_RS10045	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AV743_RS10050	COG0322	excinuclease ABC activity
AV743_RS10055	COG1472	Belongs to the glycosyl hydrolase 3 family
AV743_RS10060	COG0736	holo-[acyl-carrier-protein] synthase activity
AV743_RS10065	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AV743_RS10075	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AV743_RS10080	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AV743_RS10105	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AV743_RS10120	COG2032	superoxide dismutase activity
AV743_RS10135	COG1024	Enoyl-CoA hydratase
AV743_RS10145	COG1802	Transcriptional regulator
AV743_RS10155	COG0183	Belongs to the thiolase family
AV743_RS10160	COG1942	4-Oxalocrotonate Tautomerase
AV743_RS10170	COG4176	ABC-type proline glycine betaine transport system permease component
AV743_RS10190	COG2814	Major facilitator Superfamily
AV743_RS10195	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AV743_RS10200	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AV743_RS10230	COG2814	Major facilitator Superfamily
AV743_RS10235	COG0495	leucyl-tRNA aminoacylation
AV743_RS10250	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AV743_RS10260	COG0154	amidase activity
AV743_RS10265	COG1250	3-hydroxyacyl-CoA dehydrogenase
AV743_RS10315	COG1530	ribonuclease E activity
AV743_RS10320	COG0077	Prephenate dehydratase
AV743_RS10335	COG1132	(ABC) transporter
AV743_RS10340	COG0859	PFAM glycosyl transferase family 9
AV743_RS10365	COG2194	sulfuric ester hydrolase activity
AV743_RS10370	COG0438	transferase activity, transferring glycosyl groups
AV743_RS10375	COG0463	Glycosyl transferase, family 2
AV743_RS10380	COG0726	polysaccharide deacetylase
AV743_RS10385	COG0438	transferase activity, transferring glycosyl groups
AV743_RS10400	COG1643	Atp-dependent helicase
AV743_RS10405	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AV743_RS10405	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AV743_RS10410	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AV743_RS10420	COG0704	Plays a role in the regulation of phosphate uptake
AV743_RS10425	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AV743_RS10430	COG1960	acyl-CoA dehydrogenase activity
AV743_RS10455	COG1177	transmembrane transport
AV743_RS10460	COG1176	ABC-type spermidine putrescine transport system, permease component I
AV743_RS10465	COG3842	ATPase activity
AV743_RS10470	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AV743_RS10485	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AV743_RS10490	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AV743_RS10500	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AV743_RS10500	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AV743_RS10515	COG0372	Belongs to the citrate synthase family
AV743_RS10520	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AV743_RS10525	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AV743_RS10530	COG1053	succinate dehydrogenase
AV743_RS10535	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AV743_RS10540	COG2009	succinate dehydrogenase
AV743_RS10545	COG2188	Transcriptional regulator
AV743_RS10550	COG0039	L-malate dehydrogenase activity
AV743_RS10580	COG1981	membrane
AV743_RS10605	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AV743_RS10615	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AV743_RS10645	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AV743_RS10650	COG0148	phosphopyruvate hydratase activity
AV743_RS10660	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AV743_RS10665	COG0504	CTP synthase activity
AV743_RS10690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AV743_RS10700	COG0747	negative chemotaxis
AV743_RS10705	COG4172	Belongs to the ABC transporter superfamily
AV743_RS10710	COG1446	asparaginase
AV743_RS10740	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AV743_RS10755	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AV743_RS10760	COG0697	spore germination
AV743_RS10765	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AV743_RS10775	COG3193	protein, possibly involved in utilization of glycolate and propanediol
AV743_RS10785	COG0791	NLP P60 protein
AV743_RS10800	COG0583	DNA-binding transcription factor activity
AV743_RS10815	COG0583	DNA-binding transcription factor activity
AV743_RS10825	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AV743_RS10840	COG0670	Belongs to the BI1 family
AV743_RS10845	COG3181	Tripartite tricarboxylate transporter family receptor
AV743_RS10860	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AV743_RS10870	COG1381	Involved in DNA repair and RecF pathway recombination
AV743_RS10875	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AV743_RS10880	COG0571	ribonuclease III activity
AV743_RS10885	COG0681	Belongs to the peptidase S26 family
AV743_RS10890	COG0481	GTPase activity
AV743_RS10895	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AV743_RS10920	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AV743_RS10925	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AV743_RS10940	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AV743_RS10945	COG0416	fatty acid biosynthetic process
AV743_RS10950	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AV743_RS10955	COG1399	metal-binding, possibly nucleic acid-binding protein
AV743_RS10960	COG0424	maF-like protein
AV743_RS10970	COG3023	N-Acetylmuramoyl-L-alanine amidase
AV743_RS10985	COG3022	response to hydroperoxide
AV743_RS11000	COG1028	Short-chain dehydrogenase reductase Sdr
AV743_RS11015	COG3486	L-lysine 6-monooxygenase (NADPH) activity
AV743_RS11045	COG2814	Major facilitator Superfamily
AV743_RS11065	COG3706	GGDEF domain
AV743_RS11090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AV743_RS11095	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AV743_RS11100	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AV743_RS11105	COG1674	ftsk spoiiie
AV743_RS11110	COG0492	ferredoxin-NADP+ reductase activity
AV743_RS11115	COG1193	negative regulation of DNA recombination
AV743_RS11130	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AV743_RS11145	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AV743_RS11150	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AV743_RS11155	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AV743_RS11165	COG0745	RESPONSE REGULATOR receiver
AV743_RS11210	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AV743_RS11230	COG0612	Peptidase, M16
AV743_RS11240	COG0443	Heat shock 70 kDa protein
AV743_RS11250	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AV743_RS11260	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AV743_RS11265	COG1420	regulation of RNA biosynthetic process
AV743_RS11270	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AV743_RS11275	COG0497	DNA recombination
AV743_RS11280	COG0735	belongs to the Fur family
AV743_RS11285	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AV743_RS11290	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AV743_RS11295	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AV743_RS11330	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AV743_RS11330	COG0446	pyridine nucleotide-disulphide oxidoreductase
AV743_RS11335	COG4311	Sarcosine oxidase, delta subunit
AV743_RS11340	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AV743_RS11350	COG0583	DNA-binding transcription factor activity
AV743_RS11360	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AV743_RS11390	COG4964	Belongs to the GSP D family
AV743_RS11450	COG0181	hydroxymethylbilane synthase activity
AV743_RS11455	COG0861	Integral membrane protein TerC family
AV743_RS11460	COG0861	Integral membrane protein TerC family
AV743_RS11465	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AV743_RS11470	COG0045	succinate-CoA ligase (ADP-forming) activity
AV743_RS11480	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AV743_RS11490	COG2137	regulation of response to DNA damage stimulus
AV743_RS11495	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AV743_RS11515	COG1024	Enoyl-CoA hydratase
AV743_RS11515	COG1250	3-hydroxyacyl-CoA dehydrogenase
AV743_RS11520	COG3842	ATPase activity
AV743_RS11535	COG1028	Short-chain dehydrogenase reductase Sdr
AV743_RS11555	COG0583	DNA-binding transcription factor activity
AV743_RS11560	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AV743_RS11570	COG2974	May be involved in recombination
AV743_RS11575	COG0540	Belongs to the ATCase OTCase family
AV743_RS11640	COG0776	regulation of translation
AV743_RS11645	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AV743_RS11645	COG0072	phenylalanine-tRNA ligase activity
AV743_RS11650	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AV743_RS11655	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AV743_RS11660	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AV743_RS11675	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AV743_RS11685	COG0756	dUTP diphosphatase activity
AV743_RS11700	COG0500	methyltransferase
AV743_RS11715	COG0586	Pfam SNARE associated Golgi protein
AV743_RS11745	COG1609	Transcriptional regulator
AV743_RS11750	COG4172	Belongs to the ABC transporter superfamily
AV743_RS11755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AV743_RS11760	COG0601	transmembrane transport
AV743_RS11765	COG0747	negative chemotaxis
AV743_RS11785	COG1280	lysine exporter protein (LysE YggA)
AV743_RS11800	COG2814	Major facilitator Superfamily
AV743_RS11830	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AV743_RS11845	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AV743_RS11870	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AV743_RS11875	COG1116	anion transmembrane transporter activity
AV743_RS11885	COG1228	amidohydrolase
AV743_RS11900	COG0477	Major facilitator Superfamily
AV743_RS11910	COG3550	peptidyl-serine autophosphorylation
AV743_RS11925	COG0519	Catalyzes the synthesis of GMP from XMP
AV743_RS11925	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AV743_RS11950	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AV743_RS11955	COG1012	belongs to the aldehyde dehydrogenase family
AV743_RS11960	COG0483	inositol monophosphate 1-phosphatase activity
AV743_RS11965	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AV743_RS11975	COG1045	serine acetyltransferase
AV743_RS11980	COG0166	Belongs to the GPI family
AV743_RS11995	COG2197	response regulator
AV743_RS12010	COG0183	Belongs to the thiolase family
AV743_RS12025	COG1024	Enoyl-CoA hydratase
AV743_RS12025	COG1250	3-hydroxyacyl-CoA dehydrogenase
AV743_RS12030	COG0183	Belongs to the thiolase family
AV743_RS12065	COG3181	Tripartite tricarboxylate transporter family receptor
AV743_RS12080	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AV743_RS12080	COG1017	nitric oxide dioxygenase activity
AV743_RS12095	COG1335	isochorismatase
AV743_RS12100	COG2309	aminopeptidase activity
AV743_RS12110	COG3473	Maleate cis-trans isomerase
AV743_RS12115	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AV743_RS12120	COG2080	2 iron, 2 sulfur cluster binding
AV743_RS12155	COG1846	Transcriptional regulator
AV743_RS12175	COG0726	polysaccharide deacetylase
AV743_RS12175	COG1649	PFAM Uncharacterised BCR, COG1649
AV743_RS12180	COG1215	transferase activity, transferring glycosyl groups
AV743_RS12190	COG1902	pentaerythritol trinitrate reductase activity
AV743_RS12215	COG0251	oxidation-reduction process
AV743_RS12225	COG1832	CoA-binding protein
AV743_RS12230	COG1414	Transcriptional regulator
AV743_RS12235	COG1902	pentaerythritol trinitrate reductase activity
AV743_RS12235	COG0446	pyridine nucleotide-disulphide oxidoreductase
AV743_RS12245	COG3842	ATPase activity
AV743_RS12270	COG0583	DNA-binding transcription factor activity
AV743_RS12280	COG1028	Short-chain dehydrogenase reductase Sdr
AV743_RS12285	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
AV743_RS12290	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AV743_RS12305	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AV743_RS12305	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AV743_RS12310	COG1250	3-hydroxyacyl-CoA dehydrogenase
AV743_RS12335	COG0527	aspartate kinase activity
AV743_RS12340	COG0037	tRNA processing
AV743_RS12350	COG0825	malonyl-CoA metabolic process
AV743_RS12360	COG0215	cysteine-tRNA ligase activity
AV743_RS12375	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AV743_RS12380	COG1968	undecaprenyl-diphosphatase activity
AV743_RS12385	COG1253	flavin adenine dinucleotide binding
AV743_RS12390	COG0483	inositol monophosphate 1-phosphatase activity
AV743_RS12410	COG0668	transmembrane transport
AV743_RS12455	COG3360	Dodecin
AV743_RS12460	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AV743_RS12465	COG2850	peptidyl-arginine hydroxylation
AV743_RS12470	COG3539	Fimbrial protein
AV743_RS12475	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AV743_RS12480	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AV743_RS12495	COG0009	L-threonylcarbamoyladenylate synthase
AV743_RS12500	COG2321	neutral zinc metallopeptidase
AV743_RS12520	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AV743_RS12525	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AV743_RS12530	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AV743_RS12540	COG1074	ATP-dependent DNA helicase activity
AV743_RS12550	COG2814	Major facilitator Superfamily
AV743_RS12560	COG1686	Belongs to the peptidase S11 family
AV743_RS12570	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
AV743_RS12575	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AV743_RS12580	COG4974	Belongs to the 'phage' integrase family
AV743_RS12585	COG0583	DNA-binding transcription factor activity
AV743_RS12590	COG0028	Belongs to the TPP enzyme family
AV743_RS12605	COG0028	Belongs to the TPP enzyme family
AV743_RS12610	COG1126	abc transporter atp-binding protein
AV743_RS12615	COG0765	amino acid transport
AV743_RS12630	COG1414	Transcriptional regulator
AV743_RS12635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AV743_RS12640	COG0009	L-threonylcarbamoyladenylate synthase
AV743_RS12645	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AV743_RS12650	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AV743_RS12655	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AV743_RS12665	COG2944	sequence-specific DNA binding
AV743_RS12675	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AV743_RS12730	COG1126	abc transporter atp-binding protein
AV743_RS12735	COG0765	amino acid transport
AV743_RS12740	COG0765	amino acid transport
AV743_RS12745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AV743_RS12755	COG2423	ornithine cyclodeaminase activity
AV743_RS12770	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AV743_RS12775	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AV743_RS12785	COG0189	ligase activity
AV743_RS12790	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AV743_RS12795	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AV743_RS12800	COG2197	response regulator
AV743_RS12835	COG0135	phosphoribosylanthranilate isomerase activity
AV743_RS12850	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AV743_RS12855	COG0101	tRNA pseudouridine synthase activity
AV743_RS12865	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AV743_RS12870	COG0473	3-isopropylmalate dehydrogenase activity
AV743_RS12875	COG0066	3-isopropylmalate dehydratase activity
AV743_RS12880	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AV743_RS12890	COG1122	ATPase activity
AV743_RS12925	COG3383	formate dehydrogenase (NAD+) activity
AV743_RS12925	COG0243	molybdopterin cofactor binding
AV743_RS12955	COG0489	protein tyrosine kinase activity
AV743_RS12960	COG0746	molybdenum cofactor guanylyltransferase activity
AV743_RS12965	COG0303	'Molybdopterin
AV743_RS12970	COG1763	Mo-molybdopterin cofactor biosynthetic process
AV743_RS12980	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AV743_RS12985	COG5001	Diguanylate cyclase
AV743_RS13005	COG3842	ATPase activity
AV743_RS13015	COG0406	alpha-ribazole phosphatase activity
AV743_RS13025	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AV743_RS13035	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AV743_RS13070	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AV743_RS13075	COG1960	acyl-CoA dehydrogenase activity
AV743_RS13085	COG2867	negative regulation of translational initiation
AV743_RS13090	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AV743_RS13095	COG3706	GGDEF domain
AV743_RS13100	COG0330	HflC and HflK could
AV743_RS13115	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AV743_RS13115	COG0519	Catalyzes the synthesis of GMP from XMP
AV743_RS13125	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AV743_RS13130	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AV743_RS13135	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AV743_RS13140	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AV743_RS13150	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AV743_RS13155	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AV743_RS13160	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
AV743_RS13165	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AV743_RS13170	COG0750	zinc metalloprotease
AV743_RS13175	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AV743_RS13185	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AV743_RS13190	COG0233	cytoplasmic translational termination
AV743_RS13195	COG0528	UMP kinase activity
AV743_RS13200	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AV743_RS13205	COG0052	Belongs to the universal ribosomal protein uS2 family
AV743_RS13210	COG0024	Methionine aminopeptidase
AV743_RS13215	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AV743_RS13245	COG0285	dihydrofolate synthase activity
AV743_RS13280	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AV743_RS13290	COG1677	Flagellar hook-basal body complex protein FliE
AV743_RS13300	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AV743_RS13305	COG1317	bacterial-type flagellum organization
AV743_RS13310	COG1157	protein secretion by the type III secretion system
AV743_RS13335	COG1580	Controls the rotational direction of flagella during chemotaxis
AV743_RS13355	COG1338	Plays a role in the flagellum-specific transport system
AV743_RS13375	COG0840	transmembrane signaling receptor activity
AV743_RS13380	COG0840	transmembrane signaling receptor activity
AV743_RS13385	COG0840	transmembrane signaling receptor activity
AV743_RS13395	COG1256	bacterial-type flagellum assembly
AV743_RS13405	COG1706	bacterial-type flagellum-dependent cell motility
AV743_RS13410	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AV743_RS13425	COG1749	Flagellar hook protein flgE
AV743_RS13435	COG1558	bacterial-type flagellum-dependent cell motility
AV743_RS13440	COG1815	bacterial-type flagellum-dependent cell motility
AV743_RS13480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AV743_RS13485	COG0765	amino acid transport
AV743_RS13490	COG1126	abc transporter atp-binding protein
AV743_RS13505	COG1580	Controls the rotational direction of flagella during chemotaxis
AV743_RS13525	COG1338	Plays a role in the flagellum-specific transport system
AV743_RS13545	COG0840	transmembrane signaling receptor activity
AV743_RS13550	COG0840	transmembrane signaling receptor activity
AV743_RS13555	COG0840	transmembrane signaling receptor activity
AV743_RS13565	COG1256	bacterial-type flagellum assembly
AV743_RS13575	COG1706	bacterial-type flagellum-dependent cell motility
AV743_RS13580	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AV743_RS13595	COG1749	Flagellar hook protein flgE
AV743_RS13605	COG1558	bacterial-type flagellum-dependent cell motility
AV743_RS13610	COG1815	bacterial-type flagellum-dependent cell motility
AV743_RS13650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AV743_RS13655	COG0765	amino acid transport
AV743_RS13660	COG1126	abc transporter atp-binding protein
AV743_RS13675	COG1580	Controls the rotational direction of flagella during chemotaxis
AV743_RS13695	COG1338	Plays a role in the flagellum-specific transport system
AV743_RS13715	COG0840	transmembrane signaling receptor activity
AV743_RS13720	COG0840	transmembrane signaling receptor activity
AV743_RS13725	COG0840	transmembrane signaling receptor activity
AV743_RS13735	COG1256	bacterial-type flagellum assembly
AV743_RS13745	COG1706	bacterial-type flagellum-dependent cell motility
AV743_RS13750	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AV743_RS13765	COG1749	Flagellar hook protein flgE
AV743_RS13775	COG1558	bacterial-type flagellum-dependent cell motility
AV743_RS13780	COG1815	bacterial-type flagellum-dependent cell motility
AV743_RS13820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AV743_RS13825	COG0765	amino acid transport
AV743_RS13830	COG1126	abc transporter atp-binding protein
AV743_RS13845	COG4948	Mandelate Racemase Muconate Lactonizing
AV743_RS13850	COG3181	Tripartite tricarboxylate transporter family receptor
AV743_RS13860	COG0066	3-isopropylmalate dehydratase activity
AV743_RS13875	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AV743_RS13885	COG3181	Tripartite tricarboxylate transporter family receptor
AV743_RS13895	COG1802	Transcriptional regulator
AV743_RS13910	COG0583	DNA-binding transcription factor activity
AV743_RS13930	COG1695	Transcriptional regulator
AV743_RS13940	COG3568	Endonuclease Exonuclease Phosphatase
AV743_RS13945	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AV743_RS13965	COG3842	ATPase activity
AV743_RS13975	COG0406	alpha-ribazole phosphatase activity
AV743_RS13990	COG0505	Belongs to the CarA family
AV743_RS13995	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AV743_RS14030	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AV743_RS14035	COG1960	acyl-CoA dehydrogenase activity
AV743_RS14045	COG2867	negative regulation of translational initiation
AV743_RS14050	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AV743_RS14055	COG3706	GGDEF domain
AV743_RS14060	COG0330	HflC and HflK could
AV743_RS14075	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AV743_RS14075	COG0519	Catalyzes the synthesis of GMP from XMP
AV743_RS14085	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AV743_RS14090	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AV743_RS14095	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AV743_RS14100	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AV743_RS14110	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AV743_RS14115	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AV743_RS14120	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
AV743_RS14125	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AV743_RS14130	COG0750	zinc metalloprotease
AV743_RS14135	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AV743_RS14145	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AV743_RS14150	COG0233	cytoplasmic translational termination
AV743_RS14155	COG0528	UMP kinase activity
AV743_RS14160	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AV743_RS14165	COG0052	Belongs to the universal ribosomal protein uS2 family
AV743_RS14170	COG0024	Methionine aminopeptidase
AV743_RS14175	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AV743_RS14205	COG0285	dihydrofolate synthase activity
AV743_RS14240	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AV743_RS14250	COG1677	Flagellar hook-basal body complex protein FliE
AV743_RS14260	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AV743_RS14265	COG1317	bacterial-type flagellum organization
AV743_RS14270	COG1157	protein secretion by the type III secretion system
AV743_RS14295	COG1580	Controls the rotational direction of flagella during chemotaxis
AV743_RS14315	COG1338	Plays a role in the flagellum-specific transport system
AV743_RS14335	COG0840	transmembrane signaling receptor activity
AV743_RS14340	COG0840	transmembrane signaling receptor activity
AV743_RS14345	COG0840	transmembrane signaling receptor activity
AV743_RS14355	COG1256	bacterial-type flagellum assembly
AV743_RS14365	COG1706	bacterial-type flagellum-dependent cell motility
AV743_RS14370	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AV743_RS14385	COG1749	Flagellar hook protein flgE
AV743_RS14395	COG1558	bacterial-type flagellum-dependent cell motility
AV743_RS14400	COG1815	bacterial-type flagellum-dependent cell motility
AV743_RS14440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AV743_RS14445	COG0765	amino acid transport
AV743_RS14450	COG1126	abc transporter atp-binding protein
AV743_RS14465	COG4948	Mandelate Racemase Muconate Lactonizing
AV743_RS14470	COG3181	Tripartite tricarboxylate transporter family receptor
AV743_RS14480	COG0066	3-isopropylmalate dehydratase activity
AV743_RS14495	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AV743_RS14505	COG3181	Tripartite tricarboxylate transporter family receptor
AV743_RS14515	COG1802	Transcriptional regulator
AV743_RS14530	COG0583	DNA-binding transcription factor activity
AV743_RS14550	COG1695	Transcriptional regulator
AV743_RS14560	COG3568	Endonuclease Exonuclease Phosphatase
AV743_RS14565	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AV743_RS14595	COG0420	3'-5' exonuclease activity
AV743_RS14600	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AV743_RS14630	COG0395	ABC-type sugar transport system, permease component
AV743_RS14640	COG3842	ATPase activity
AV743_RS14665	COG3181	Tripartite tricarboxylate transporter family receptor
AV743_RS14700	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AV743_RS14725	COG0602	queuosine metabolic process
AV743_RS14730	COG0720	synthase
AV743_RS14735	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AV743_RS14740	COG0235	Class ii aldolase
AV743_RS14770	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
AV743_RS14770	COG3064	Membrane
AV743_RS14770	COG3210	domain, Protein
AV743_RS14775	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AV743_RS14775	COG0047	phosphoribosylformylglycinamidine synthase activity
AV743_RS14780	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AV743_RS14785	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AV743_RS14785	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AV743_RS14790	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AV743_RS14805	COG3539	Fimbrial protein
AV743_RS14815	COG2050	protein possibly involved in aromatic compounds catabolism
AV743_RS14820	COG1024	Enoyl-CoA hydratase
AV743_RS14825	COG1012	belongs to the aldehyde dehydrogenase family
AV743_RS14845	COG2151	metal-sulfur cluster biosynthetic enzyme
AV743_RS14850	COG3396	Phenylacetate-CoA oxygenase
AV743_RS14855	COG3460	Phenylacetate-CoA oxygenase
AV743_RS14860	COG3396	Phenylacetate-CoA oxygenase
AV743_RS14865	COG3327	negative regulation of DNA-templated transcription, initiation
AV743_RS14875	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AV743_RS14880	COG0501	Belongs to the peptidase M48B family
AV743_RS14885	COG1162	GTPase activity
AV743_RS14900	COG0601	transmembrane transport
AV743_RS14905	COG0747	negative chemotaxis
AV743_RS14950	COG0668	transmembrane transport
AV743_RS14955	COG0165	Argininosuccinate lyase
AV743_RS14975	COG0542	response to heat
AV743_RS14980	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AV743_RS14995	COG0494	nUDIX hydrolase
AV743_RS15000	COG3530	Putative quorum-sensing-regulated virulence factor
AV743_RS15010	COG1595	DNA-templated transcription, initiation
AV743_RS15015	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AV743_RS15050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AV743_RS15055	COG0765	amino acid transport
AV743_RS15060	COG0765	amino acid transport
AV743_RS15085	COG2988	succinylglutamate desuccinylase activity
AV743_RS15110	COG3181	Tripartite tricarboxylate transporter family receptor
AV743_RS15115	COG2084	Dehydrogenase
AV743_RS15130	COG1619	proteins homologs of microcin C7 resistance protein MccF
AV743_RS15145	COG2814	Major facilitator Superfamily
AV743_RS15155	COG0583	DNA-binding transcription factor activity
AV743_RS15195	COG0672	)-iron permease
AV743_RS15210	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
AV743_RS15215	COG1028	Short-chain dehydrogenase reductase Sdr
AV743_RS15220	COG3243	poly(R)-hydroxyalkanoic acid synthase
AV743_RS15230	COG0564	pseudouridine synthase activity
AV743_RS15240	COG1199	ATP-dependent helicase activity
AV743_RS15245	COG2183	response to ionizing radiation
AV743_RS15250	COG0180	Tryptophanyl-tRNA synthetase
AV743_RS15275	COG4774	siderophore transport
AV743_RS15280	COG3712	iron ion homeostasis
AV743_RS15285	COG1595	DNA-templated transcription, initiation
AV743_RS15310	COG3181	Tripartite tricarboxylate transporter family receptor
AV743_RS15320	COG0583	DNA-binding transcription factor activity
AV743_RS15325	COG1028	Short-chain dehydrogenase reductase Sdr
AV743_RS15330	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AV743_RS15335	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AV743_RS15340	COG0508	dehydrogenase complex catalyzes the overall conversion of
AV743_RS15345	COG0567	Dehydrogenase, E1 component
AV743_RS15355	COG1522	sequence-specific DNA binding
AV743_RS15365	COG0280	phosphate acetyltransferase
AV743_RS15365	COG0281	malic enzyme
AV743_RS15370	COG3539	Fimbrial protein
AV743_RS15390	COG0613	PHP domain protein
AV743_RS15400	COG2333	competence protein COMEC
AV743_RS15400	COG0658	competence protein
AV743_RS15420	COG0084	hydrolase, TatD family'
AV743_RS15425	COG1136	(ABC) transporter
AV743_RS15440	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AV743_RS15450	COG1028	Short-chain dehydrogenase reductase Sdr
AV743_RS15455	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AV743_RS15470	COG1022	Amp-dependent synthetase and ligase
AV743_RS15505	COG2205	protein histidine kinase activity
AV743_RS15510	COG0745	RESPONSE REGULATOR receiver
AV743_RS15525	COG1295	ribonuclease BN
AV743_RS15540	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AV743_RS15570	COG1534	Rna-binding protein
AV743_RS15575	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AV743_RS15580	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AV743_RS15590	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AV743_RS15600	COG0248	Ppx GppA phosphatase
AV743_RS15625	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AV743_RS15645	COG2732	(Barnase) inhibitor
AV743_RS15665	COG0436	Aminotransferase
AV743_RS15670	COG0741	lytic transglycosylase activity
AV743_RS15675	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AV743_RS15700	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AV743_RS15700	COG1648	precorrin-2 dehydrogenase activity
AV743_RS15705	COG3468	outer membrane autotransporter barrel domain protein
AV743_RS15715	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AV743_RS15720	COG2027	D-alanyl-D-alanine carboxypeptidase
AV743_RS15725	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AV743_RS15730	COG0343	queuine tRNA-ribosyltransferase activity
AV743_RS15735	COG1862	Preprotein translocase
AV743_RS15740	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AV743_RS15745	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AV743_RS15760	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AV743_RS15765	COG1702	phosphate starvation-inducible protein PhoH
AV743_RS15770	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AV743_RS15775	COG4535	Mg2 and Co2 transporter CorC
AV743_RS15785	COG0667	Aldo Keto reductase
AV743_RS15810	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AV743_RS15815	COG0745	RESPONSE REGULATOR receiver
AV743_RS15820	COG2201	protein-glutamate methylesterase activity
AV743_RS15830	COG0840	transmembrane signaling receptor activity
AV743_RS15845	COG0745	RESPONSE REGULATOR receiver
AV743_RS15885	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AV743_RS15895	COG0739	heme binding
AV743_RS15905	COG0521	Mo-molybdopterin cofactor biosynthetic process
AV743_RS15920	COG0306	phosphate transporter
AV743_RS15925	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AV743_RS15955	COG0625	glutathione transferase activity
AV743_RS15970	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AV743_RS15975	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AV743_RS15980	COG0126	phosphoglycerate kinase activity
AV743_RS15985	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AV743_RS15990	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AV743_RS15995	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AV743_RS16005	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AV743_RS16010	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AV743_RS16015	COG0508	dehydrogenase complex catalyzes the overall conversion of
AV743_RS16020	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AV743_RS16030	COG4566	intracellular signal transduction
AV743_RS16035	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AV743_RS16040	COG0339	signal peptide processing
AV743_RS16045	COG1999	signal sequence binding
AV743_RS16075	COG1187	pseudouridine synthase activity
AV743_RS16080	COG3161	chorismate lyase activity
AV743_RS16095	COG0667	Aldo Keto reductase
AV743_RS16105	COG0335	large ribosomal subunit rRNA binding
AV743_RS16140	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AV743_RS16160	COG0450	alkyl hydroperoxide reductase
AV743_RS16165	COG1960	acyl-CoA dehydrogenase activity
AV743_RS16180	COG0123	including yeast histone deacetylase and acetoin utilization protein
AV743_RS16185	COG2951	lytic endotransglycosylase activity
AV743_RS16200	COG1596	polysaccharide export
AV743_RS16200	COG1555	photosystem II stabilization
AV743_RS16205	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AV743_RS16210	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AV743_RS16215	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AV743_RS16235	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AV743_RS16240	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AV743_RS16245	COG0287	Prephenate dehydrogenase
AV743_RS16255	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AV743_RS16270	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AV743_RS16280	COG2814	Major facilitator Superfamily
AV743_RS16310	COG0583	DNA-binding transcription factor activity
AV743_RS16350	COG0583	DNA-binding transcription factor activity
AV743_RS16365	COG0179	Fumarylacetoacetate (FAA) hydrolase
AV743_RS16390	COG1053	succinate dehydrogenase
AV743_RS16395	COG1012	belongs to the aldehyde dehydrogenase family
AV743_RS16400	COG2079	MmgE PrpD family protein
AV743_RS16410	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AV743_RS16465	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AV743_RS16480	COG0667	Aldo Keto reductase
AV743_RS16490	COG5265	(ABC) transporter
AV743_RS16540	COG0439	Biotin carboxylase
AV743_RS16545	COG2188	Transcriptional regulator
AV743_RS16570	COG0511	ligase activity, forming carbon-carbon bonds
AV743_RS16600	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
AV743_RS16620	COG0500	methyltransferase
AV743_RS16625	COG5265	(ABC) transporter
AV743_RS16645	COG0308	aminopeptidase N
AV743_RS16650	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AV743_RS16665	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AV743_RS16670	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AV743_RS16675	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AV743_RS16680	COG0560	Phosphoserine phosphatase
AV743_RS16685	COG0583	DNA-binding transcription factor activity
AV743_RS16690	COG3181	Tripartite tricarboxylate transporter family receptor
AV743_RS16695	COG0028	Belongs to the TPP enzyme family
AV743_RS16710	COG4774	siderophore transport
AV743_RS16715	COG4774	siderophore transport
AV743_RS16725	COG1007	ATP synthesis coupled electron transport
AV743_RS16740	COG0713	ATP synthesis coupled electron transport
AV743_RS16750	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AV743_RS16755	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AV743_RS16760	COG1034	ATP synthesis coupled electron transport
AV743_RS16770	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AV743_RS16775	COG0649	NAD binding
AV743_RS16780	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AV743_RS16785	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AV743_RS16790	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AV743_RS16795	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AV743_RS16825	COG0671	phosphoesterase, PA-phosphatase related
AV743_RS16835	COG1597	lipid kinase activity
AV743_RS16840	COG0583	DNA-binding transcription factor activity
AV743_RS16845	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AV743_RS16855	COG1733	regulation of RNA biosynthetic process
AV743_RS16860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AV743_RS16880	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
AV743_RS16900	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AV743_RS16920	COG3608	succinylglutamate desuccinylase aspartoacylase
AV743_RS16925	COG0626	cystathionine gamma-synthase activity
AV743_RS16930	COG0583	DNA-binding transcription factor activity
AV743_RS16965	COG3799	methylaspartate ammonia-lyase activity
AV743_RS16975	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AV743_RS16985	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AV743_RS16990	COG0149	triose-phosphate isomerase activity
AV743_RS17010	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AV743_RS17025	COG1185	polyribonucleotide nucleotidyltransferase activity
AV743_RS17030	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AV743_RS17045	COG1183	phosphatidylcholine synthase activity
AV743_RS17050	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AV743_RS17055	COG0440	acetolactate synthase activity
AV743_RS17060	COG0028	Belongs to the TPP enzyme family
AV743_RS17155	COG1464	Belongs to the NlpA lipoprotein family
AV743_RS17185	COG4211	Belongs to the binding-protein-dependent transport system permease family
AV743_RS17195	COG0154	amidase activity
AV743_RS17200	COG0288	reversible hydration of carbon dioxide
AV743_RS17215	COG0514	ATP-dependent DNA helicase (RecQ)
AV743_RS17220	COG2255	four-way junction helicase activity
AV743_RS17235	COG0632	four-way junction helicase activity
AV743_RS17240	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AV743_RS17260	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AV743_RS17270	COG0006	proline dipeptidase activity
AV743_RS17295	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AV743_RS17310	COG4783	chaperone-mediated protein folding
AV743_RS17315	COG0429	hydrolase of the alpha beta-hydrolase fold
AV743_RS17345	COG0513	Belongs to the DEAD box helicase family
AV743_RS17365	COG1058	Belongs to the CinA family
AV743_RS17365	COG1546	Belongs to the CinA family
AV743_RS17370	COG1414	Transcriptional regulator
AV743_RS17390	COG0167	dihydroorotate dehydrogenase activity
AV743_RS17395	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AV743_RS17410	COG0583	DNA-binding transcription factor activity
AV743_RS17470	COG0281	malic enzyme
AV743_RS17470	COG0280	phosphate acetyltransferase
AV743_RS17485	COG0601	transmembrane transport
AV743_RS17490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AV743_RS17495	COG4172	Belongs to the ABC transporter superfamily
AV743_RS17525	COG0640	Transcriptional regulator
AV743_RS17540	COG3135	benzoate transporter
AV743_RS17545	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AV743_RS17550	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AV743_RS17555	COG0742	ribosomal rna small subunit methyltransferase
AV743_RS17570	COG3639	organic phosphonate transmembrane transporter activity
AV743_RS17575	COG3639	organic phosphonate transmembrane transporter activity
AV743_RS17615	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AV743_RS17620	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AV743_RS17630	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AV743_RS17635	COG1058	Belongs to the CinA family
AV743_RS17635	COG1546	Belongs to the CinA family
AV743_RS17640	COG0284	orotidine-5'-phosphate decarboxylase activity
AV743_RS17645	COG1252	NADH dehydrogenase
AV743_RS17660	COG3468	outer membrane autotransporter barrel domain protein
AV743_RS17665	COG0459	protein refolding
AV743_RS17670	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AV743_RS17690	COG1053	succinate dehydrogenase
AV743_RS17700	COG0583	DNA-binding transcription factor activity
AV743_RS17705	COG1053	succinate dehydrogenase
AV743_RS17725	COG3706	GGDEF domain
AV743_RS17765	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
AV743_RS17775	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AV743_RS17785	COG0069	glutamate synthase activity
AV743_RS17790	COG2391	methyltransferase activity
AV743_RS17795	COG0679	Auxin Efflux Carrier
AV743_RS17820	COG0557	exoribonuclease II activity
AV743_RS17825	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AV743_RS17835	COG3128	pkhd-type hydroxylase
AV743_RS17840	COG0776	regulation of translation
AV743_RS17870	COG0642	Histidine kinase
AV743_RS17875	COG3158	transport of potassium into the cell
AV743_RS17880	COG0137	argininosuccinate synthase activity
AV743_RS17885	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AV743_RS17890	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AV743_RS17900	COG0583	DNA-binding transcription factor activity
AV743_RS17910	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AV743_RS17930	COG2186	Transcriptional regulator
AV743_RS17940	COG2223	nitrite transmembrane transporter activity
AV743_RS17950	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AV743_RS17955	COG0450	alkyl hydroperoxide reductase
AV743_RS17975	COG1214	PFAM Peptidase M22, glycoprotease
AV743_RS17980	COG1573	uracil-dna glycosylase
AV743_RS17985	COG0477	Major facilitator Superfamily
AV743_RS17990	COG1196	nuclear chromosome segregation
AV743_RS18000	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AV743_RS18005	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AV743_RS18020	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AV743_RS18025	COG1122	ATPase activity
AV743_RS18030	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AV743_RS18035	COG1268	BioY protein
AV743_RS18055	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AV743_RS18090	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AV743_RS18095	COG2878	Part of a membrane complex involved in electron transport
AV743_RS18110	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AV743_RS18115	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AV743_RS18120	COG0251	oxidation-reduction process
AV743_RS18130	COG3228	Belongs to the MtfA family
AV743_RS18135	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AV743_RS18145	COG0133	tryptophan synthase activity
AV743_RS18150	COG0159	tryptophan synthase activity
AV743_RS18155	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AV743_RS18175	COG1530	ribonuclease E activity
AV743_RS18185	COG0546	phosphoglycolate phosphatase activity
AV743_RS18190	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AV743_RS18195	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AV743_RS18265	COG1196	nuclear chromosome segregation
AV743_RS18335	COG2135	peptidase activity
AV743_RS18350	COG0494	nUDIX hydrolase
AV743_RS18355	COG0442	prolyl-tRNA aminoacylation
AV743_RS18360	COG0824	Thioesterase
AV743_RS18365	COG0811	peptide transport
AV743_RS18370	COG0848	biopolymer transport protein
AV743_RS18380	COG0823	Involved in the tonB-independent uptake of proteins
AV743_RS18395	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AV743_RS18400	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AV743_RS18455	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AV743_RS18460	COG3568	Endonuclease Exonuclease Phosphatase
AV743_RS18465	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AV743_RS18500	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AV743_RS18510	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AV743_RS18525	COG1137	ATPase activity
AV743_RS18540	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AV743_RS18545	COG2010	Cytochrome c
AV743_RS18545	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AV743_RS18555	COG1660	Displays ATPase and GTPase activities
AV743_RS18560	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AV743_RS18600	COG3181	Tripartite tricarboxylate transporter family receptor
AV743_RS18610	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AV743_RS18615	COG2890	protein-(glutamine-N5) methyltransferase activity
AV743_RS18620	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AV743_RS18625	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AV743_RS18665	COG1960	acyl-CoA dehydrogenase activity
AV743_RS18675	COG0183	Belongs to the thiolase family
AV743_RS18680	COG1522	sequence-specific DNA binding
AV743_RS18685	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AV743_RS18705	COG1024	Enoyl-CoA hydratase
AV743_RS18720	COG0604	alcohol dehydrogenase
AV743_RS18725	COG2072	flavoprotein involved in K transport
AV743_RS18740	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AV743_RS18750	COG1960	acyl-CoA dehydrogenase activity
AV743_RS18755	COG1960	acyl-CoA dehydrogenase activity
AV743_RS18760	COG0277	FAD linked oxidase domain protein
AV743_RS18770	COG3181	Tripartite tricarboxylate transporter family receptor
AV743_RS18795	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AV743_RS18805	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AV743_RS18810	COG3181	Tripartite tricarboxylate transporter family receptor
AV743_RS18815	COG1960	acyl-CoA dehydrogenase activity
AV743_RS18835	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AV743_RS18845	COG1960	acyl-CoA dehydrogenase activity
AV743_RS18865	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AV743_RS18870	COG0022	dehydrogenase e1 component
AV743_RS18875	COG1024	Enoyl-CoA hydratase
AV743_RS18880	COG0508	dehydrogenase complex catalyzes the overall conversion of
AV743_RS18900	COG0683	leucine binding
AV743_RS18905	COG0559	Belongs to the binding-protein-dependent transport system permease family
AV743_RS18910	COG0411	ABC transporter
AV743_RS18920	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AV743_RS18935	COG3181	Tripartite tricarboxylate transporter family receptor
AV743_RS18960	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AV743_RS18965	COG0793	Belongs to the peptidase S41A family
AV743_RS18970	COG4942	peptidase
AV743_RS18975	COG0588	phosphoglycerate mutase activity
AV743_RS18980	COG1054	Belongs to the UPF0176 family
AV743_RS18985	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AV743_RS18990	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AV743_RS18995	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AV743_RS19000	COG3181	Tripartite tricarboxylate transporter family receptor
AV743_RS19015	COG2226	methyltransferase
AV743_RS19020	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AV743_RS19035	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AV743_RS19060	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AV743_RS19085	COG1335	isochorismatase
AV743_RS19090	COG2309	aminopeptidase activity
AV743_RS19100	COG3473	Maleate cis-trans isomerase
AV743_RS19110	COG2068	MobA-Related Protein
AV743_RS19135	COG2204	response regulator
AV743_RS19140	COG5000	phosphorelay sensor kinase activity
AV743_RS19150	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AV743_RS19150	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AV743_RS19160	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
AV743_RS19185	COG0583	DNA-binding transcription factor activity
AV743_RS19205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AV743_RS19210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AV743_RS19225	COG0758	DNA mediated transformation
AV743_RS19230	COG1522	sequence-specific DNA binding
AV743_RS19240	COG0242	peptide deformylase activity
AV743_RS19245	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AV743_RS19255	COG0546	phosphoglycolate phosphatase activity
AV743_RS19275	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AV743_RS19280	COG1942	4-Oxalocrotonate Tautomerase
AV743_RS19285	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AV743_RS19310	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AV743_RS19330	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AV743_RS19335	COG1024	Enoyl-CoA hydratase
AV743_RS19340	COG1414	Transcriptional regulator
AV743_RS19345	COG0318	PFAM AMP-dependent synthetase and ligase
AV743_RS19350	COG3181	Tripartite tricarboxylate transporter family receptor
AV743_RS19395	COG3422	double-strand break repair
AV743_RS19400	COG0330	HflC and HflK could
AV743_RS19410	COG0251	oxidation-reduction process
AV743_RS19420	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
AV743_RS19430	COG0583	DNA-binding transcription factor activity
AV743_RS19435	COG2814	Major facilitator Superfamily
AV743_RS19440	COG0129	dihydroxy-acid dehydratase activity
AV743_RS19445	COG2207	Transcriptional regulator
AV743_RS19450	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AV743_RS19460	COG0657	acetylesterase activity
AV743_RS19465	COG0747	negative chemotaxis
AV743_RS19470	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AV743_RS19475	COG2808	Putative FMN-binding domain
AV743_RS19490	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AV743_RS19495	COG1970	mechanosensitive ion channel activity
AV743_RS19500	COG0723	plastoquinol--plastocyanin reductase activity
AV743_RS19505	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AV743_RS19510	COG2857	Cytochrome c1
AV743_RS19515	COG0625	glutathione transferase activity
AV743_RS19520	COG2969	positive regulation of protein catabolic process
AV743_RS19570	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AV743_RS19575	COG4988	ABC transporter
AV743_RS19585	COG1294	oxidase, subunit
AV743_RS19620	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AV743_RS19625	COG0405	Gamma-glutamyltransferase
AV743_RS19635	COG3181	Tripartite tricarboxylate transporter family receptor
AV743_RS19645	COG0114	fumarate hydratase activity
AV743_RS19650	COG0802	atpase or kinase
AV743_RS19655	COG0860	N-Acetylmuramoyl-L-alanine amidase
AV743_RS19660	COG0586	Pfam SNARE associated Golgi protein
AV743_RS19665	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AV743_RS19670	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AV743_RS19675	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AV743_RS19690	COG0617	tRNA 3'-terminal CCA addition
AV743_RS19715	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AV743_RS19720	COG2188	Transcriptional regulator
AV743_RS19730	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AV743_RS19740	COG1028	Short-chain dehydrogenase reductase Sdr
AV743_RS19765	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AV743_RS19770	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AV743_RS19775	COG1012	belongs to the aldehyde dehydrogenase family
AV743_RS19805	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AV743_RS19810	COG1024	Enoyl-CoA hydratase
AV743_RS19830	COG1024	Enoyl-CoA hydratase
AV743_RS19845	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AV743_RS19850	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AV743_RS19860	COG2226	methyltransferase
AV743_RS19870	COG1194	a g-specific adenine glycosylase
AV743_RS19880	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AV743_RS19885	COG2177	Part of the ABC transporter FtsEX involved in
AV743_RS19890	COG2884	Cell division ATP-binding protein ftsE
AV743_RS19895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AV743_RS19900	COG4597	amino acid ABC transporter
AV743_RS19905	COG0765	amino acid transport
AV743_RS19910	COG1126	abc transporter atp-binding protein
AV743_RS19925	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AV743_RS19930	COG0477	Major facilitator Superfamily
AV743_RS19940	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AV743_RS19945	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AV743_RS19960	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AV743_RS19965	COG0237	dephospho-CoA kinase activity
AV743_RS19970	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
AV743_RS20035	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AV743_RS20050	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AV743_RS20065	COG1652	LysM domain
AV743_RS20080	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AV743_RS20085	COG1956	GAF domain-containing protein
AV743_RS20090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AV743_RS20115	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AV743_RS20140	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AV743_RS20160	COG0438	transferase activity, transferring glycosyl groups
AV743_RS20170	COG0402	S-adenosylhomocysteine deaminase activity
AV743_RS20210	COG0629	single-stranded DNA binding
AV743_RS20215	COG2814	Major facilitator Superfamily
AV743_RS20230	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AV743_RS20235	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AV743_RS20240	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AV743_RS20250	COG1965	Belongs to the frataxin family
AV743_RS20265	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AV743_RS20270	COG1333	cytochrome c biogenesis protein
AV743_RS20280	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AV743_RS20295	COG4232	protein-disulfide reductase activity
AV743_RS20300	COG1324	tolerance protein
AV743_RS20305	COG0537	adenosine 5'-monophosphoramidase activity
AV743_RS20310	COG0203	ribosomal protein L17
AV743_RS20315	COG0202	RNA polymerase activity
AV743_RS20320	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AV743_RS20325	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AV743_RS20330	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AV743_RS20335	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AV743_RS20340	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AV743_RS20345	COG0201	protein transport
AV743_RS20350	COG0200	Binds to the 23S rRNA
AV743_RS20355	COG1841	ribosomal large subunit assembly
AV743_RS20360	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AV743_RS20365	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AV743_RS20370	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AV743_RS20375	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AV743_RS20380	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AV743_RS20385	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AV743_RS20390	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AV743_RS20395	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AV743_RS20415	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AV743_RS20420	COG0255	Belongs to the universal ribosomal protein uL29 family
AV743_RS20425	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AV743_RS20430	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AV743_RS20435	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AV743_RS20440	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AV743_RS20445	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AV743_RS20450	COG0089	rRNA binding
AV743_RS20455	COG0088	Forms part of the polypeptide exit tunnel
AV743_RS20460	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AV743_RS20465	COG0051	transcription antitermination factor activity, RNA binding
AV743_RS20470	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AV743_RS20475	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AV743_RS20480	COG0049	tRNA binding
AV743_RS20485	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AV743_RS20500	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AV743_RS20510	COG0628	permease
AV743_RS20520	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AV743_RS20530	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AV743_RS20535	COG0351	phosphomethylpyrimidine kinase
AV743_RS20540	COG2022	thiamine diphosphate biosynthetic process
AV743_RS20545	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AV743_RS20550	COG4206	TonB-dependent receptor
AV743_RS20575	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AV743_RS20585	COG3781	membrane
AV743_RS20590	COG1522	sequence-specific DNA binding
AV743_RS20595	COG0028	Belongs to the TPP enzyme family
AV743_RS20605	COG1012	belongs to the aldehyde dehydrogenase family
AV743_RS20610	COG1028	Short-chain dehydrogenase reductase Sdr
AV743_RS20615	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AV743_RS20620	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AV743_RS20645	COG2922	Belongs to the Smg family
AV743_RS20650	COG1629	transport
AV743_RS20660	COG2358	TRAP transporter, solute receptor (TAXI family
AV743_RS20670	COG3181	Tripartite tricarboxylate transporter family receptor
AV743_RS20675	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AV743_RS20690	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AV743_RS20695	COG0183	Belongs to the thiolase family
AV743_RS20725	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AV743_RS20740	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AV743_RS20750	COG1414	Transcriptional regulator
AV743_RS20755	COG1028	Short-chain dehydrogenase reductase Sdr
AV743_RS20760	COG2031	fatty acid transporter
AV743_RS20765	COG1250	3-hydroxyacyl-CoA dehydrogenase
AV743_RS20775	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AV743_RS20780	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AV743_RS20790	COG4257	antibiotic catabolic process
AV743_RS20800	COG0753	catalase activity
AV743_RS20805	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AV743_RS20810	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AV743_RS20820	COG2175	clavaminate synthase activity
AV743_RS20825	COG1473	amidohydrolase
AV743_RS20830	COG4608	Belongs to the ABC transporter superfamily
AV743_RS20835	COG0444	Belongs to the ABC transporter superfamily
AV743_RS20850	COG0747	negative chemotaxis
AV743_RS20855	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AV743_RS20890	COG0436	Aminotransferase
AV743_RS20895	COG1278	Cold shock