locus-tag	class	description
B3913_RS00005	COG0445	tRNA wobble uridine modification
B3913_RS00010	COG0357	Ribosomal RNA small subunit methyltransferase G
B3913_RS00015	COG1192	Involved in chromosome partitioning
B3913_RS00025	COG1475	DNA binding
B3913_RS00030	COG0252	asparaginase activity
B3913_RS00055	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
B3913_RS00065	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
B3913_RS00075	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
B3913_RS00080	COG0081	regulation of translation
B3913_RS00085	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
B3913_RS00090	COG0222	ribosome binding
B3913_RS00095	COG0085	RNA polymerase activity
B3913_RS00100	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
B3913_RS00140	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B3913_RS00165	COG1024	Enoyl-CoA hydratase
B3913_RS00185	COG0752	glycyl-tRNA synthetase alpha subunit
B3913_RS00190	COG0751	glycine-tRNA ligase activity
B3913_RS00195	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
B3913_RS00200	COG0204	Acyl-transferase
B3913_RS00215	COG0242	peptide deformylase activity
B3913_RS00250	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
B3913_RS00255	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B3913_RS00260	COG2813	Specifically methylates the guanine in position
B3913_RS00260	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B3913_RS00270	COG2223	nitrite transmembrane transporter activity
B3913_RS00280	COG1794	racemase activity, acting on amino acids and derivatives
B3913_RS00285	COG1126	abc transporter atp-binding protein
B3913_RS00290	COG0765	amino acid transport
B3913_RS00295	COG0765	amino acid transport
B3913_RS00300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B3913_RS00355	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B3913_RS00385	COG0326	Molecular chaperone. Has ATPase activity
B3913_RS00390	COG0625	glutathione transferase activity
B3913_RS00405	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B3913_RS00410	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
B3913_RS00440	COG0438	transferase activity, transferring glycosyl groups
B3913_RS00445	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
B3913_RS00450	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
B3913_RS00480	COG0859	PFAM glycosyl transferase family 9
B3913_RS00495	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
B3913_RS00505	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
B3913_RS00510	COG1127	ABC transporter
B3913_RS00535	COG1686	Belongs to the peptidase S11 family
B3913_RS00545	COG2921	Belongs to the UPF0250 family
B3913_RS00550	COG0321	lipoyl(octanoyl) transferase activity
B3913_RS00555	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
B3913_RS00590	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
B3913_RS00600	COG0018	arginyl-trna synthetase
B3913_RS00620	COG0395	ABC-type sugar transport system, permease component
B3913_RS00625	COG1175	transmembrane transport
B3913_RS00630	COG1653	transport
B3913_RS00635	COG3842	ATPase activity
B3913_RS00640	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
B3913_RS00655	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
B3913_RS00675	COG1609	Transcriptional regulator
B3913_RS00685	COG0154	amidase activity
B3913_RS00690	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B3913_RS00700	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
B3913_RS00710	COG0583	DNA-binding transcription factor activity
B3913_RS00725	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
B3913_RS00730	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B3913_RS00745	COG1802	Transcriptional regulator
B3913_RS00760	COG1024	Enoyl-CoA hydratase
B3913_RS00775	COG3181	Tripartite tricarboxylate transporter family receptor
B3913_RS00790	COG1984	allophanate hydrolase subunit 2
B3913_RS00795	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
B3913_RS00805	COG0583	DNA-binding transcription factor activity
B3913_RS00810	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B3913_RS00820	COG5002	protein histidine kinase activity
B3913_RS00830	COG5002	protein histidine kinase activity
B3913_RS00835	COG0745	RESPONSE REGULATOR receiver
B3913_RS00840	COG2226	methyltransferase
B3913_RS00855	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
B3913_RS00875	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
B3913_RS00885	COG0513	Belongs to the DEAD box helicase family
B3913_RS00890	COG1280	lysine exporter protein (LysE YggA)
B3913_RS00895	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
B3913_RS00930	COG1054	Belongs to the UPF0176 family
B3913_RS00935	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B3913_RS00935	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B3913_RS00945	COG0489	protein tyrosine kinase activity
B3913_RS00960	COG0717	Belongs to the dCTP deaminase family
B3913_RS00990	COG2081	HI0933 family
B3913_RS01000	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
B3913_RS01010	COG0404	The glycine cleavage system catalyzes the degradation of glycine
B3913_RS01015	COG0509	glycine decarboxylation via glycine cleavage system
B3913_RS01020	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B3913_RS01020	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B3913_RS01060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B3913_RS01075	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
B3913_RS01085	COG1414	Transcriptional regulator
B3913_RS01090	COG1028	Short-chain dehydrogenase reductase Sdr
B3913_RS01095	COG2031	fatty acid transporter
B3913_RS01100	COG1250	3-hydroxyacyl-CoA dehydrogenase
B3913_RS01110	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
B3913_RS01115	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
B3913_RS01125	COG4257	antibiotic catabolic process
B3913_RS01145	COG1012	belongs to the aldehyde dehydrogenase family
B3913_RS01150	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
B3913_RS01155	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B3913_RS01180	COG1028	Short-chain dehydrogenase reductase Sdr
B3913_RS01190	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B3913_RS01200	COG2188	Transcriptional regulator
B3913_RS01205	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
B3913_RS01230	COG0617	tRNA 3'-terminal CCA addition
B3913_RS01245	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
B3913_RS01250	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
B3913_RS01255	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
B3913_RS01260	COG0586	Pfam SNARE associated Golgi protein
B3913_RS01265	COG0860	N-Acetylmuramoyl-L-alanine amidase
B3913_RS01270	COG0802	atpase or kinase
B3913_RS01275	COG0114	fumarate hydratase activity
B3913_RS01285	COG3181	Tripartite tricarboxylate transporter family receptor
B3913_RS01295	COG0405	Gamma-glutamyltransferase
B3913_RS01300	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B3913_RS01310	COG1960	acyl-CoA dehydrogenase activity
B3913_RS01335	COG1294	oxidase, subunit
B3913_RS01345	COG4988	ABC transporter
B3913_RS01350	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
B3913_RS01355	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
B3913_RS01370	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
B3913_RS01395	COG2969	positive regulation of protein catabolic process
B3913_RS01400	COG0625	glutathione transferase activity
B3913_RS01405	COG2857	Cytochrome c1
B3913_RS01410	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
B3913_RS01415	COG0723	plastoquinol--plastocyanin reductase activity
B3913_RS01420	COG1970	mechanosensitive ion channel activity
B3913_RS01425	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
B3913_RS01440	COG2808	Putative FMN-binding domain
B3913_RS01445	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B3913_RS01450	COG0747	negative chemotaxis
B3913_RS01455	COG0657	acetylesterase activity
B3913_RS01465	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B3913_RS01470	COG2207	Transcriptional regulator
B3913_RS01475	COG0129	dihydroxy-acid dehydratase activity
B3913_RS01480	COG2814	Major facilitator Superfamily
B3913_RS01485	COG0583	DNA-binding transcription factor activity
B3913_RS01495	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
B3913_RS01565	COG1024	Enoyl-CoA hydratase
B3913_RS01570	COG1960	acyl-CoA dehydrogenase activity
B3913_RS01595	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
B3913_RS01600	COG0352	thiamine-phosphate diphosphorylase activity
B3913_RS01615	COG1678	Uncharacterized ACR, COG1678
B3913_RS01620	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
B3913_RS01625	COG0540	Belongs to the ATCase OTCase family
B3913_RS01640	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
B3913_RS01650	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B3913_RS01685	COG1234	tRNA 3'-trailer cleavage
B3913_RS01730	COG1683	Conserved Protein
B3913_RS01735	COG1120	ATPase activity
B3913_RS01740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B3913_RS01745	COG4558	Periplasmic binding protein
B3913_RS01750	COG3720	iron ion transport
B3913_RS01760	COG3712	iron ion homeostasis
B3913_RS01765	COG1595	DNA-templated transcription, initiation
B3913_RS01800	COG1802	Transcriptional regulator
B3913_RS01810	COG3069	C4-dicarboxylate transmembrane transporter activity
B3913_RS01820	COG1012	belongs to the aldehyde dehydrogenase family
B3913_RS01855	COG2860	membrane
B3913_RS01860	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
B3913_RS01865	COG0708	Exodeoxyribonuclease III
B3913_RS01870	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
B3913_RS01875	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
B3913_RS01880	COG0154	amidase activity
B3913_RS01885	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
B3913_RS01890	COG1077	Cell shape determining protein MreB Mrl
B3913_RS01895	COG1792	Involved in formation and maintenance of cell shape
B3913_RS01905	COG0768	penicillin binding
B3913_RS01910	COG0772	Belongs to the SEDS family
B3913_RS01915	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
B3913_RS01920	COG0471	metal ion transport
B3913_RS01925	COG1309	transcriptional regulator
B3913_RS01935	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
B3913_RS01950	COG2823	Periplasmic or secreted lipoprotein
B3913_RS01955	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
B3913_RS01970	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B3913_RS01990	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B3913_RS02000	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B3913_RS02025	COG0492	ferredoxin-NADP+ reductase activity
B3913_RS02035	COG3181	Tripartite tricarboxylate transporter family receptor
B3913_RS02040	COG1250	3-hydroxyacyl-CoA dehydrogenase
B3913_RS02040	COG1024	Enoyl-CoA hydratase
B3913_RS02045	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B3913_RS02050	COG0028	Belongs to the TPP enzyme family
B3913_RS02075	COG3181	Tripartite tricarboxylate transporter family receptor
B3913_RS02085	COG0697	spore germination
B3913_RS02110	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
B3913_RS02115	COG0463	Glycosyl transferase, family 2
B3913_RS02130	COG0786	glutamate:sodium symporter activity
B3913_RS02140	COG2031	fatty acid transporter
B3913_RS02155	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B3913_RS02160	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B3913_RS02170	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
B3913_RS02185	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B3913_RS02195	COG1285	pathogenesis
B3913_RS02200	COG1253	flavin adenine dinucleotide binding
B3913_RS02205	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B3913_RS02210	COG1024	Enoyl-CoA hydratase
B3913_RS02215	COG3181	Tripartite tricarboxylate transporter family receptor
B3913_RS02220	COG0583	DNA-binding transcription factor activity
B3913_RS02225	COG1960	acyl-CoA dehydrogenase activity
B3913_RS02235	COG0183	Belongs to the thiolase family
B3913_RS02255	COG0583	DNA-binding transcription factor activity
B3913_RS02260	COG1278	Cold shock
B3913_RS02270	COG1802	Transcriptional regulator
B3913_RS02275	COG1012	belongs to the aldehyde dehydrogenase family
B3913_RS02280	COG2031	fatty acid transporter
B3913_RS02285	COG1017	nitric oxide dioxygenase activity
B3913_RS02285	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B3913_RS02290	COG0251	oxidation-reduction process
B3913_RS02315	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B3913_RS02325	COG0583	DNA-binding transcription factor activity
B3913_RS02330	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B3913_RS02340	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
B3913_RS02345	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
B3913_RS02350	COG0546	phosphoglycolate phosphatase activity
B3913_RS02360	COG1530	ribonuclease E activity
B3913_RS02375	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
B3913_RS02380	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
B3913_RS02385	COG0159	tryptophan synthase activity
B3913_RS02390	COG0133	tryptophan synthase activity
B3913_RS02400	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B3913_RS02405	COG3228	Belongs to the MtfA family
B3913_RS02415	COG0251	oxidation-reduction process
B3913_RS02420	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
B3913_RS02425	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
B3913_RS02440	COG2878	Part of a membrane complex involved in electron transport
B3913_RS02445	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
B3913_RS02480	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B3913_RS02500	COG1268	BioY protein
B3913_RS02505	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
B3913_RS02510	COG1122	ATPase activity
B3913_RS02515	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B3913_RS02530	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B3913_RS02535	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
B3913_RS02545	COG1196	nuclear chromosome segregation
B3913_RS02550	COG0477	Major facilitator Superfamily
B3913_RS02555	COG1573	uracil-dna glycosylase
B3913_RS02560	COG1214	PFAM Peptidase M22, glycoprotease
B3913_RS02575	COG0450	alkyl hydroperoxide reductase
B3913_RS02580	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B3913_RS02590	COG2223	nitrite transmembrane transporter activity
B3913_RS02600	COG2186	Transcriptional regulator
B3913_RS02620	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B3913_RS02630	COG0583	DNA-binding transcription factor activity
B3913_RS02640	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B3913_RS02645	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
B3913_RS02650	COG0137	argininosuccinate synthase activity
B3913_RS02655	COG3158	transport of potassium into the cell
B3913_RS02660	COG0642	Histidine kinase
B3913_RS02690	COG0776	regulation of translation
B3913_RS02695	COG3128	pkhd-type hydroxylase
B3913_RS02705	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B3913_RS02710	COG0557	exoribonuclease II activity
B3913_RS02735	COG0679	Auxin Efflux Carrier
B3913_RS02740	COG2391	methyltransferase activity
B3913_RS02745	COG0069	glutamate synthase activity
B3913_RS02755	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B3913_RS02765	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
B3913_RS02770	COG1262	PFAM Formylglycine-generating sulfatase enzyme
B3913_RS02805	COG3706	GGDEF domain
B3913_RS02825	COG1053	succinate dehydrogenase
B3913_RS02830	COG0583	DNA-binding transcription factor activity
B3913_RS02840	COG1053	succinate dehydrogenase
B3913_RS02860	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
B3913_RS02865	COG0459	protein refolding
B3913_RS02870	COG3468	outer membrane autotransporter barrel domain protein
B3913_RS02885	COG1252	NADH dehydrogenase
B3913_RS02890	COG0284	orotidine-5'-phosphate decarboxylase activity
B3913_RS02895	COG1058	Belongs to the CinA family
B3913_RS02895	COG1546	Belongs to the CinA family
B3913_RS02900	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
B3913_RS02910	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B3913_RS02915	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
B3913_RS02950	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
B3913_RS02955	COG3639	organic phosphonate transmembrane transporter activity
B3913_RS02960	COG3639	organic phosphonate transmembrane transporter activity
B3913_RS02980	COG0742	ribosomal rna small subunit methyltransferase
B3913_RS02985	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
B3913_RS02990	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
B3913_RS02995	COG3135	benzoate transporter
B3913_RS03010	COG0640	Transcriptional regulator
B3913_RS03040	COG4172	Belongs to the ABC transporter superfamily
B3913_RS03045	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B3913_RS03050	COG0601	transmembrane transport
B3913_RS03060	COG0280	phosphate acetyltransferase
B3913_RS03060	COG0281	malic enzyme
B3913_RS03120	COG0583	DNA-binding transcription factor activity
B3913_RS03130	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
B3913_RS03135	COG0167	dihydroorotate dehydrogenase activity
B3913_RS03155	COG1414	Transcriptional regulator
B3913_RS03160	COG1058	Belongs to the CinA family
B3913_RS03160	COG1546	Belongs to the CinA family
B3913_RS03180	COG0513	Belongs to the DEAD box helicase family
B3913_RS03210	COG0429	hydrolase of the alpha beta-hydrolase fold
B3913_RS03215	COG4783	chaperone-mediated protein folding
B3913_RS03230	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
B3913_RS03255	COG0006	proline dipeptidase activity
B3913_RS03265	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B3913_RS03285	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
B3913_RS03290	COG0632	four-way junction helicase activity
B3913_RS03305	COG2255	four-way junction helicase activity
B3913_RS03310	COG0514	ATP-dependent DNA helicase (RecQ)
B3913_RS03325	COG0288	reversible hydration of carbon dioxide
B3913_RS03330	COG0154	amidase activity
B3913_RS03340	COG4211	Belongs to the binding-protein-dependent transport system permease family
B3913_RS03370	COG1464	Belongs to the NlpA lipoprotein family
B3913_RS03510	COG1196	nuclear chromosome segregation
B3913_RS03575	COG2135	peptidase activity
B3913_RS03590	COG0494	nUDIX hydrolase
B3913_RS03595	COG0442	prolyl-tRNA aminoacylation
B3913_RS03600	COG0824	Thioesterase
B3913_RS03605	COG0811	peptide transport
B3913_RS03610	COG0848	biopolymer transport protein
B3913_RS03620	COG0823	Involved in the tonB-independent uptake of proteins
B3913_RS03635	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B3913_RS03640	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
B3913_RS03670	COG0700	Nucleoside recognition
B3913_RS03675	COG0469	pyruvate kinase activity
B3913_RS03680	COG1929	Belongs to the glycerate kinase type-1 family
B3913_RS03685	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
B3913_RS03690	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B3913_RS03695	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
B3913_RS03705	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
B3913_RS03715	COG2154	pterin-4-alpha-carbinolamine dehydratase
B3913_RS03740	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B3913_RS03745	COG0154	amidase activity
B3913_RS03755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B3913_RS03760	COG0601	transmembrane transport
B3913_RS03765	COG0747	negative chemotaxis
B3913_RS03785	COG0019	diaminopimelate decarboxylase activity
B3913_RS03805	COG2353	YceI-like domain
B3913_RS03810	COG4774	siderophore transport
B3913_RS03815	COG3712	iron ion homeostasis
B3913_RS03855	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
B3913_RS03860	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
B3913_RS03865	COG0211	Belongs to the bacterial ribosomal protein bL27 family
B3913_RS03870	COG0261	This protein binds to 23S rRNA in the presence of protein L20
B3913_RS03880	COG0142	geranyltranstransferase activity
B3913_RS03890	COG0583	DNA-binding transcription factor activity
B3913_RS03900	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
B3913_RS03905	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B3913_RS03920	COG2994	toxin metabolic process
B3913_RS03930	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
B3913_RS03935	COG2274	protein secretion by the type I secretion system
B3913_RS03940	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B3913_RS03945	COG1538	Outer membrane efflux protein
B3913_RS03965	COG0765	amino acid transport
B3913_RS03970	COG1126	abc transporter atp-binding protein
B3913_RS03990	COG1028	Short-chain dehydrogenase reductase Sdr
B3913_RS04000	COG1802	Transcriptional regulator
B3913_RS04010	COG1802	Transcriptional regulator
B3913_RS04020	COG0318	PFAM AMP-dependent synthetase and ligase
B3913_RS04030	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B3913_RS04050	COG0028	Belongs to the TPP enzyme family
B3913_RS04070	COG0308	aminopeptidase N
B3913_RS04075	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
B3913_RS04090	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
B3913_RS04095	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
B3913_RS04100	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
B3913_RS04105	COG0560	Phosphoserine phosphatase
B3913_RS04110	COG0583	DNA-binding transcription factor activity
B3913_RS04115	COG3181	Tripartite tricarboxylate transporter family receptor
B3913_RS04120	COG0028	Belongs to the TPP enzyme family
B3913_RS04135	COG4774	siderophore transport
B3913_RS04140	COG4774	siderophore transport
B3913_RS04150	COG1007	ATP synthesis coupled electron transport
B3913_RS04165	COG0713	ATP synthesis coupled electron transport
B3913_RS04175	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B3913_RS04180	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
B3913_RS04185	COG1034	ATP synthesis coupled electron transport
B3913_RS04195	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
B3913_RS04200	COG0649	NAD binding
B3913_RS04205	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B3913_RS04210	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B3913_RS04215	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B3913_RS04220	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
B3913_RS04245	COG0671	phosphoesterase, PA-phosphatase related
B3913_RS04255	COG1597	lipid kinase activity
B3913_RS04260	COG0583	DNA-binding transcription factor activity
B3913_RS04265	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
B3913_RS04275	COG1733	regulation of RNA biosynthetic process
B3913_RS04280	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B3913_RS04285	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B3913_RS04300	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
B3913_RS04320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B3913_RS04340	COG3608	succinylglutamate desuccinylase aspartoacylase
B3913_RS04345	COG0626	cystathionine gamma-synthase activity
B3913_RS04350	COG0583	DNA-binding transcription factor activity
B3913_RS04390	COG3799	methylaspartate ammonia-lyase activity
B3913_RS04400	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
B3913_RS04410	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
B3913_RS04415	COG0149	triose-phosphate isomerase activity
B3913_RS04435	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B3913_RS04450	COG1185	polyribonucleotide nucleotidyltransferase activity
B3913_RS04455	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
B3913_RS04465	COG1183	phosphatidylcholine synthase activity
B3913_RS04470	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
B3913_RS04475	COG0440	acetolactate synthase activity
B3913_RS04480	COG0028	Belongs to the TPP enzyme family
B3913_RS04495	COG5265	(ABC) transporter
B3913_RS04500	COG0500	methyltransferase
B3913_RS04515	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
B3913_RS04535	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
B3913_RS04545	COG0511	ligase activity, forming carbon-carbon bonds
B3913_RS04570	COG2188	Transcriptional regulator
B3913_RS04575	COG0439	Biotin carboxylase
B3913_RS04580	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B3913_RS04625	COG5265	(ABC) transporter
B3913_RS04635	COG0667	Aldo Keto reductase
B3913_RS04650	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
B3913_RS04685	COG0583	DNA-binding transcription factor activity
B3913_RS04705	COG2814	Major facilitator Superfamily
B3913_RS04715	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
B3913_RS04730	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
B3913_RS04740	COG0287	Prephenate dehydrogenase
B3913_RS04745	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
B3913_RS04750	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
B3913_RS04770	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
B3913_RS04775	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
B3913_RS04780	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B3913_RS04785	COG1555	photosystem II stabilization
B3913_RS04785	COG1596	polysaccharide export
B3913_RS04800	COG2951	lytic endotransglycosylase activity
B3913_RS04805	COG0123	including yeast histone deacetylase and acetoin utilization protein
B3913_RS04820	COG1960	acyl-CoA dehydrogenase activity
B3913_RS04825	COG0450	alkyl hydroperoxide reductase
B3913_RS04840	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
B3913_RS04845	COG4208	sulfate ABC transporter
B3913_RS04850	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
B3913_RS04855	COG0175	sulfate reduction
B3913_RS04885	COG0335	large ribosomal subunit rRNA binding
B3913_RS04900	COG0667	Aldo Keto reductase
B3913_RS04910	COG2814	Major facilitator Superfamily
B3913_RS04915	COG3161	chorismate lyase activity
B3913_RS04920	COG1187	pseudouridine synthase activity
B3913_RS04930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B3913_RS04950	COG1999	signal sequence binding
B3913_RS04955	COG0339	signal peptide processing
B3913_RS04960	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
B3913_RS04965	COG4566	intracellular signal transduction
B3913_RS04975	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
B3913_RS04980	COG0508	dehydrogenase complex catalyzes the overall conversion of
B3913_RS04985	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B3913_RS04990	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
B3913_RS05000	COG1385	rRNA (uridine-N3-)-methyltransferase activity
B3913_RS05005	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
B3913_RS05010	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
B3913_RS05015	COG0126	phosphoglycerate kinase activity
B3913_RS05020	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
B3913_RS05025	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
B3913_RS05040	COG0625	glutathione transferase activity
B3913_RS05070	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
B3913_RS05080	COG0521	Mo-molybdopterin cofactor biosynthetic process
B3913_RS05090	COG0739	heme binding
B3913_RS05100	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
B3913_RS05135	COG0745	RESPONSE REGULATOR receiver
B3913_RS05150	COG0840	transmembrane signaling receptor activity
B3913_RS05160	COG2201	protein-glutamate methylesterase activity
B3913_RS05165	COG0745	RESPONSE REGULATOR receiver
B3913_RS05170	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
B3913_RS05195	COG0667	Aldo Keto reductase
B3913_RS05205	COG4535	Mg2 and Co2 transporter CorC
B3913_RS05210	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
B3913_RS05215	COG1702	phosphate starvation-inducible protein PhoH
B3913_RS05220	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
B3913_RS05235	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B3913_RS05240	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B3913_RS05245	COG1862	Preprotein translocase
B3913_RS05250	COG0343	queuine tRNA-ribosyltransferase activity
B3913_RS05255	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
B3913_RS05260	COG2027	D-alanyl-D-alanine carboxypeptidase
B3913_RS05265	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
B3913_RS05275	COG3468	outer membrane autotransporter barrel domain protein
B3913_RS05280	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
B3913_RS05280	COG1648	precorrin-2 dehydrogenase activity
B3913_RS05305	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
B3913_RS05310	COG0741	lytic transglycosylase activity
B3913_RS05315	COG0436	Aminotransferase
B3913_RS05325	COG0281	malic enzyme
B3913_RS05325	COG0280	phosphate acetyltransferase
B3913_RS05335	COG2732	(Barnase) inhibitor
B3913_RS05350	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
B3913_RS05375	COG0248	Ppx GppA phosphatase
B3913_RS05385	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B3913_RS05395	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B3913_RS05400	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
B3913_RS05405	COG1534	Rna-binding protein
B3913_RS05430	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
B3913_RS05445	COG1295	ribonuclease BN
B3913_RS05455	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
B3913_RS05460	COG0745	RESPONSE REGULATOR receiver
B3913_RS05465	COG2205	protein histidine kinase activity
B3913_RS05500	COG1022	Amp-dependent synthetase and ligase
B3913_RS05515	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
B3913_RS05520	COG1028	Short-chain dehydrogenase reductase Sdr
B3913_RS05525	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
B3913_RS05530	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
B3913_RS05545	COG1136	(ABC) transporter
B3913_RS05550	COG0084	hydrolase, TatD family'
B3913_RS05585	COG0613	PHP domain protein
B3913_RS05600	COG3539	Fimbrial protein
B3913_RS05605	COG0280	phosphate acetyltransferase
B3913_RS05605	COG0281	malic enzyme
B3913_RS05615	COG1522	sequence-specific DNA binding
B3913_RS05620	COG1297	OPT oligopeptide transporter protein
B3913_RS05625	COG1297	OPT oligopeptide transporter protein
B3913_RS05630	COG0567	Dehydrogenase, E1 component
B3913_RS05635	COG0508	dehydrogenase complex catalyzes the overall conversion of
B3913_RS05640	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B3913_RS05645	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
B3913_RS05650	COG1028	Short-chain dehydrogenase reductase Sdr
B3913_RS05655	COG0583	DNA-binding transcription factor activity
B3913_RS05665	COG3181	Tripartite tricarboxylate transporter family receptor
B3913_RS05685	COG0180	Tryptophanyl-tRNA synthetase
B3913_RS05690	COG2183	response to ionizing radiation
B3913_RS05695	COG1199	ATP-dependent helicase activity
B3913_RS05705	COG0564	pseudouridine synthase activity
B3913_RS05715	COG3243	poly(R)-hydroxyalkanoic acid synthase
B3913_RS05720	COG1028	Short-chain dehydrogenase reductase Sdr
B3913_RS05725	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
B3913_RS05740	COG0672	)-iron permease
B3913_RS05780	COG0583	DNA-binding transcription factor activity
B3913_RS05790	COG2814	Major facilitator Superfamily
B3913_RS05805	COG1619	proteins homologs of microcin C7 resistance protein MccF
B3913_RS05820	COG2084	Dehydrogenase
B3913_RS05825	COG3181	Tripartite tricarboxylate transporter family receptor
B3913_RS05850	COG2988	succinylglutamate desuccinylase activity
B3913_RS05880	COG0765	amino acid transport
B3913_RS05885	COG0765	amino acid transport
B3913_RS05890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B3913_RS05925	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B3913_RS05930	COG1595	DNA-templated transcription, initiation
B3913_RS05940	COG3530	Putative quorum-sensing-regulated virulence factor
B3913_RS05945	COG0494	nUDIX hydrolase
B3913_RS05960	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B3913_RS05965	COG0542	response to heat
B3913_RS05975	COG3468	outer membrane autotransporter barrel domain protein
B3913_RS05980	COG3468	outer membrane autotransporter barrel domain protein
B3913_RS05990	COG5441	Belongs to the UPF0261 family
B3913_RS05995	COG5564	TIM-barrel signal transduction protein
B3913_RS06010	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
B3913_RS06025	COG1477	protein flavinylation
B3913_RS06045	COG1131	(ABC) transporter
B3913_RS06050	COG0842	Transport permease protein
B3913_RS06060	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
B3913_RS06065	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
B3913_RS06065	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
B3913_RS06070	COG1562	ergosterol biosynthetic process
B3913_RS06075	COG1562	ergosterol biosynthetic process
B3913_RS06080	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
B3913_RS06085	COG1028	Short-chain dehydrogenase reductase Sdr
B3913_RS06105	COG2304	oxidoreductase activity
B3913_RS06125	COG0534	Mate efflux family protein
B3913_RS06135	COG0254	rRNA binding
B3913_RS06140	COG3483	tryptophan 2,3-dioxygenase activity
B3913_RS06145	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
B3913_RS06150	COG2003	Belongs to the UPF0758 family
B3913_RS06155	COG1047	Peptidyl-prolyl cis-trans
B3913_RS06160	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
B3913_RS06165	COG0625	glutathione transferase activity
B3913_RS06185	COG0523	cobalamin synthesis protein
B3913_RS06195	COG0583	DNA-binding transcription factor activity
B3913_RS06205	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
B3913_RS06210	COG1187	pseudouridine synthase activity
B3913_RS06215	COG0779	Required for maturation of 30S ribosomal subunits
B3913_RS06220	COG0195	Participates in both transcription termination and antitermination
B3913_RS06220	COG2251	uridine kinase activity
B3913_RS06225	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
B3913_RS06230	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
B3913_RS06235	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
B3913_RS06255	COG1611	Belongs to the LOG family
B3913_RS06270	COG0412	Dienelactone hydrolase
B3913_RS06275	COG1283	sodium-dependent phosphate transmembrane transporter activity
B3913_RS06280	COG1760	l-serine dehydratase
B3913_RS06285	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
B3913_RS06290	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
B3913_RS06300	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
B3913_RS06325	COG2311	Membrane
B3913_RS06335	COG0697	spore germination
B3913_RS06350	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
B3913_RS06370	COG0559	Belongs to the binding-protein-dependent transport system permease family
B3913_RS06385	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
B3913_RS06395	COG1653	transport
B3913_RS06400	COG1175	transmembrane transport
B3913_RS06405	COG0395	ABC-type sugar transport system, permease component
B3913_RS06410	COG3842	ATPase activity
B3913_RS06435	COG2363	Small membrane protein
B3913_RS06450	COG1464	Belongs to the NlpA lipoprotein family
B3913_RS06460	COG0688	phosphatidylethanolamine metabolic process
B3913_RS06475	COG0095	Lipoate-protein ligase
B3913_RS06490	COG0625	glutathione transferase activity
B3913_RS06495	COG0386	Belongs to the glutathione peroxidase family
B3913_RS06515	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B3913_RS06550	COG2259	Doxx family
B3913_RS06565	COG0667	Aldo Keto reductase
B3913_RS06595	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
B3913_RS06610	COG1640	4-alpha-glucanotransferase
B3913_RS06620	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
B3913_RS06630	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
B3913_RS06670	COG0392	lysyltransferase activity
B3913_RS06685	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B3913_RS06690	COG3568	Endonuclease Exonuclease Phosphatase
B3913_RS06695	COG1695	Transcriptional regulator
B3913_RS06715	COG0583	DNA-binding transcription factor activity
B3913_RS06730	COG1802	Transcriptional regulator
B3913_RS06740	COG3181	Tripartite tricarboxylate transporter family receptor
B3913_RS06750	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B3913_RS06765	COG0066	3-isopropylmalate dehydratase activity
B3913_RS06775	COG3181	Tripartite tricarboxylate transporter family receptor
B3913_RS06780	COG4948	Mandelate Racemase Muconate Lactonizing
B3913_RS06795	COG1126	abc transporter atp-binding protein
B3913_RS06800	COG0765	amino acid transport
B3913_RS06805	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B3913_RS06845	COG1815	bacterial-type flagellum-dependent cell motility
B3913_RS06850	COG1558	bacterial-type flagellum-dependent cell motility
B3913_RS06860	COG1749	Flagellar hook protein flgE
B3913_RS06875	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
B3913_RS06880	COG1706	bacterial-type flagellum-dependent cell motility
B3913_RS06890	COG1256	bacterial-type flagellum assembly
B3913_RS06900	COG0840	transmembrane signaling receptor activity
B3913_RS06905	COG0840	transmembrane signaling receptor activity
B3913_RS06910	COG0840	transmembrane signaling receptor activity
B3913_RS06930	COG1338	Plays a role in the flagellum-specific transport system
B3913_RS06950	COG1580	Controls the rotational direction of flagella during chemotaxis
B3913_RS06975	COG1157	protein secretion by the type III secretion system
B3913_RS06980	COG1317	bacterial-type flagellum organization
B3913_RS06985	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B3913_RS06995	COG1677	Flagellar hook-basal body complex protein FliE
B3913_RS07005	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
B3913_RS07040	COG0285	dihydrofolate synthase activity
B3913_RS07070	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
B3913_RS07075	COG0024	Methionine aminopeptidase
B3913_RS07080	COG0052	Belongs to the universal ribosomal protein uS2 family
B3913_RS07085	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
B3913_RS07090	COG0528	UMP kinase activity
B3913_RS07095	COG0233	cytoplasmic translational termination
B3913_RS07100	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
B3913_RS07110	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
B3913_RS07115	COG0750	zinc metalloprotease
B3913_RS07120	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B3913_RS07125	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
B3913_RS07130	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B3913_RS07135	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
B3913_RS07145	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B3913_RS07150	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
B3913_RS07155	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B3913_RS07160	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
B3913_RS07170	COG0519	Catalyzes the synthesis of GMP from XMP
B3913_RS07170	COG0518	GMP synthase (glutamine-hydrolyzing) activity
B3913_RS07185	COG0330	HflC and HflK could
B3913_RS07190	COG3706	GGDEF domain
B3913_RS07195	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
B3913_RS07205	COG2867	negative regulation of translational initiation
B3913_RS07215	COG1960	acyl-CoA dehydrogenase activity
B3913_RS07220	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
B3913_RS07250	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
B3913_RS07255	COG0505	Belongs to the CarA family
B3913_RS07260	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
B3913_RS07270	COG0406	alpha-ribazole phosphatase activity
B3913_RS07280	COG3842	ATPase activity
B3913_RS07300	COG5001	Diguanylate cyclase
B3913_RS07305	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
B3913_RS07315	COG1763	Mo-molybdopterin cofactor biosynthetic process
B3913_RS07320	COG0303	'Molybdopterin
B3913_RS07325	COG0746	molybdenum cofactor guanylyltransferase activity
B3913_RS07330	COG0489	protein tyrosine kinase activity
B3913_RS07360	COG3383	formate dehydrogenase (NAD+) activity
B3913_RS07360	COG0243	molybdopterin cofactor binding
B3913_RS07365	COG0437	4 iron, 4 sulfur cluster binding
B3913_RS07395	COG1122	ATPase activity
B3913_RS07405	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
B3913_RS07410	COG0066	3-isopropylmalate dehydratase activity
B3913_RS07415	COG0473	3-isopropylmalate dehydrogenase activity
B3913_RS07420	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
B3913_RS07430	COG0101	tRNA pseudouridine synthase activity
B3913_RS07435	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
B3913_RS07450	COG0135	phosphoribosylanthranilate isomerase activity
B3913_RS07465	COG3022	response to hydroperoxide
B3913_RS07475	COG1289	transmembrane transporter activity
B3913_RS07495	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B3913_RS07505	COG2197	response regulator
B3913_RS07510	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
B3913_RS07515	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
B3913_RS07520	COG0189	ligase activity
B3913_RS07530	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B3913_RS07535	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B3913_RS07545	COG2423	ornithine cyclodeaminase activity
B3913_RS07555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B3913_RS07560	COG0765	amino acid transport
B3913_RS07565	COG0765	amino acid transport
B3913_RS07570	COG1126	abc transporter atp-binding protein
B3913_RS07625	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
B3913_RS07635	COG2944	sequence-specific DNA binding
B3913_RS07640	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
B3913_RS07645	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
B3913_RS07650	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
B3913_RS07655	COG0009	L-threonylcarbamoyladenylate synthase
B3913_RS07660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B3913_RS07665	COG1414	Transcriptional regulator
B3913_RS07680	COG0765	amino acid transport
B3913_RS07685	COG1126	abc transporter atp-binding protein
B3913_RS07690	COG0028	Belongs to the TPP enzyme family
B3913_RS07705	COG0028	Belongs to the TPP enzyme family
B3913_RS07710	COG0583	DNA-binding transcription factor activity
B3913_RS07715	COG4974	Belongs to the 'phage' integrase family
B3913_RS07720	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
B3913_RS07725	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
B3913_RS07740	COG1686	Belongs to the peptidase S11 family
B3913_RS07750	COG2814	Major facilitator Superfamily
B3913_RS07760	COG1074	ATP-dependent DNA helicase activity
B3913_RS07765	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
B3913_RS07770	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
B3913_RS07775	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
B3913_RS07795	COG2321	neutral zinc metallopeptidase
B3913_RS07800	COG0009	L-threonylcarbamoyladenylate synthase
B3913_RS07840	COG3360	Dodecin
B3913_RS07845	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
B3913_RS07850	COG2850	peptidyl-arginine hydroxylation
B3913_RS07855	COG3539	Fimbrial protein
B3913_RS07860	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
B3913_RS07865	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B3913_RS07870	COG1994	Peptidase M50
B3913_RS07880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B3913_RS07885	COG0765	amino acid transport
B3913_RS07890	COG1126	abc transporter atp-binding protein
B3913_RS07895	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B3913_RS07900	COG1758	RNA polymerase activity
B3913_RS07905	COG0194	GDP metabolic process
B3913_RS07910	COG3258	Cytochrome c
B3913_RS07915	COG2863	cytochrome
B3913_RS07920	COG1028	Short-chain dehydrogenase reductase Sdr
B3913_RS07925	COG0791	NLP P60 protein
B3913_RS07930	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
B3913_RS07950	COG1561	YicC-like family, N-terminal region
B3913_RS07955	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
B3913_RS07970	COG2200	EAL domain
B3913_RS07970	COG2199	diguanylate cyclase activity
B3913_RS07975	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
B3913_RS07985	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B3913_RS07990	COG0174	glutamine synthetase
B3913_RS08000	COG2204	response regulator
B3913_RS08005	COG0583	DNA-binding transcription factor activity
B3913_RS08010	COG1741	Belongs to the pirin family
B3913_RS08015	COG1741	Belongs to the pirin family
B3913_RS08025	COG3842	ATPase activity
B3913_RS08030	COG1178	ABC-type Fe3 transport system permease component
B3913_RS08035	COG1840	ABC-type Fe3 transport system, periplasmic component
B3913_RS08045	COG0583	DNA-binding transcription factor activity
B3913_RS08055	COG0656	L-ascorbic acid biosynthetic process
B3913_RS08070	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
B3913_RS08075	COG0583	DNA-binding transcription factor activity
B3913_RS08090	COG0783	Belongs to the Dps family
B3913_RS08125	COG0438	transferase activity, transferring glycosyl groups
B3913_RS08140	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
B3913_RS08165	COG0300	oxidoreductase activity
B3913_RS08210	COG0861	Integral membrane protein TerC family
B3913_RS08215	COG1028	Short-chain dehydrogenase reductase Sdr
B3913_RS08235	COG0714	Associated with various cellular activities
B3913_RS08265	COG3119	arylsulfatase activity
B3913_RS08290	COG2197	response regulator
B3913_RS08300	COG2944	sequence-specific DNA binding
B3913_RS08305	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
B3913_RS08310	COG0625	glutathione transferase activity
B3913_RS08340	COG0179	Fumarylacetoacetate (FAA) hydrolase
B3913_RS08345	COG1028	Short-chain dehydrogenase reductase Sdr
B3913_RS08390	COG0431	NADPH-dependent FMN reductase
B3913_RS08420	COG1028	Short-chain dehydrogenase reductase Sdr
B3913_RS08425	COG0583	DNA-binding transcription factor activity
B3913_RS08440	COG3181	Tripartite tricarboxylate transporter family receptor
B3913_RS08445	COG2111	Na H antiporter
B3913_RS08445	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
B3913_RS08450	COG1006	Multisubunit Na H antiporter MnhC subunit
B3913_RS08455	COG0651	ATP synthesis coupled electron transport
B3913_RS08460	COG1863	multisubunit Na H antiporter MnhE subunit
B3913_RS08465	COG2212	antiporter activity
B3913_RS08490	COG0590	tRNA wobble adenosine to inosine editing
B3913_RS08495	COG1619	proteins homologs of microcin C7 resistance protein MccF
B3913_RS08500	COG1024	Enoyl-CoA hydratase
B3913_RS08515	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
B3913_RS08520	COG0488	(ABC) transporter
B3913_RS08555	COG1017	nitric oxide dioxygenase activity
B3913_RS08555	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B3913_RS08560	COG1959	2 iron, 2 sulfur cluster binding
B3913_RS08565	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B3913_RS08585	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
B3913_RS08590	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
B3913_RS08595	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
B3913_RS08600	COG0084	hydrolase, TatD family'
B3913_RS08615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B3913_RS08625	COG1126	abc transporter atp-binding protein
B3913_RS08630	COG0010	Belongs to the arginase family
B3913_RS08635	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
B3913_RS08640	COG1012	belongs to the aldehyde dehydrogenase family
B3913_RS08650	COG0028	Belongs to the TPP enzyme family
B3913_RS08660	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
B3913_RS08660	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
B3913_RS08670	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B3913_RS08685	COG3189	MarR family transcriptional regulator
B3913_RS08710	COG4336	lyase activity
B3913_RS08720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B3913_RS08720	COG2205	protein histidine kinase activity
B3913_RS08725	COG2197	response regulator
B3913_RS08730	COG3210	domain, Protein
B3913_RS08730	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
B3913_RS08730	COG3064	Membrane
B3913_RS08740	COG3121	Chaperone
B3913_RS08745	COG3188	usher protein
B3913_RS08750	COG3539	Fimbrial protein
B3913_RS08755	COG2831	hemolysin activation secretion protein
B3913_RS08770	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B3913_RS08795	COG0583	DNA-binding transcription factor activity
B3913_RS08820	COG0668	transmembrane transport
B3913_RS08840	COG0483	inositol monophosphate 1-phosphatase activity
B3913_RS08845	COG1253	flavin adenine dinucleotide binding
B3913_RS08850	COG1968	undecaprenyl-diphosphatase activity
B3913_RS08855	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B3913_RS08870	COG0215	cysteine-tRNA ligase activity
B3913_RS08880	COG0825	malonyl-CoA metabolic process
B3913_RS08890	COG0037	tRNA processing
B3913_RS08895	COG0527	aspartate kinase activity
B3913_RS08920	COG1250	3-hydroxyacyl-CoA dehydrogenase
B3913_RS08925	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
B3913_RS08925	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
B3913_RS08940	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B3913_RS08945	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
B3913_RS08950	COG1028	Short-chain dehydrogenase reductase Sdr
B3913_RS08960	COG0583	DNA-binding transcription factor activity
B3913_RS08990	COG3842	ATPase activity
B3913_RS09000	COG0446	pyridine nucleotide-disulphide oxidoreductase
B3913_RS09000	COG1902	pentaerythritol trinitrate reductase activity
B3913_RS09005	COG1414	Transcriptional regulator
B3913_RS09010	COG1832	CoA-binding protein
B3913_RS09020	COG0251	oxidation-reduction process
B3913_RS09045	COG1902	pentaerythritol trinitrate reductase activity
B3913_RS09055	COG1215	transferase activity, transferring glycosyl groups
B3913_RS09060	COG1649	PFAM Uncharacterised BCR, COG1649
B3913_RS09060	COG0726	polysaccharide deacetylase
B3913_RS09080	COG1846	Transcriptional regulator
B3913_RS09100	COG0166	Belongs to the GPI family
B3913_RS09105	COG1045	serine acetyltransferase
B3913_RS09115	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
B3913_RS09120	COG0483	inositol monophosphate 1-phosphatase activity
B3913_RS09125	COG1012	belongs to the aldehyde dehydrogenase family
B3913_RS09130	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
B3913_RS09145	COG0210	DNA helicase
B3913_RS09150	COG0598	Magnesium transport protein CorA
B3913_RS09160	COG0747	negative chemotaxis
B3913_RS09165	COG0601	transmembrane transport
B3913_RS09170	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B3913_RS09175	COG4172	Belongs to the ABC transporter superfamily
B3913_RS09180	COG1846	Transcriptional regulator
B3913_RS09230	COG4964	Belongs to the GSP D family
B3913_RS09270	COG2204	response regulator
B3913_RS09285	COG1595	DNA-templated transcription, initiation
B3913_RS09295	COG3474	cytochrome
B3913_RS09300	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
B3913_RS09315	COG3384	dioxygenase
B3913_RS09320	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
B3913_RS09345	COG2885	chlorophyll binding
B3913_RS09380	COG0697	spore germination
B3913_RS09385	COG0730	response to heat
B3913_RS09400	COG0583	DNA-binding transcription factor activity
B3913_RS09405	COG0427	acetyl-CoA hydrolase
B3913_RS09460	COG1250	3-hydroxyacyl-CoA dehydrogenase
B3913_RS09465	COG0154	amidase activity
B3913_RS09475	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
B3913_RS09490	COG0495	leucyl-tRNA aminoacylation
B3913_RS09495	COG2814	Major facilitator Superfamily
B3913_RS09525	COG0267	Belongs to the bacterial ribosomal protein bL33 family
B3913_RS09530	COG0227	Belongs to the bacterial ribosomal protein bL28 family
B3913_RS09535	COG2814	Major facilitator Superfamily
B3913_RS09540	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
B3913_RS09555	COG4176	ABC-type proline glycine betaine transport system permease component
B3913_RS09565	COG1942	4-Oxalocrotonate Tautomerase
B3913_RS09570	COG0183	Belongs to the thiolase family
B3913_RS09580	COG1802	Transcriptional regulator
B3913_RS09590	COG1024	Enoyl-CoA hydratase
B3913_RS09605	COG2032	superoxide dismutase activity
B3913_RS09620	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
B3913_RS09645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B3913_RS09650	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B3913_RS09660	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
B3913_RS09665	COG0736	holo-[acyl-carrier-protein] synthase activity
B3913_RS09670	COG1472	Belongs to the glycosyl hydrolase 3 family
B3913_RS09675	COG0322	excinuclease ABC activity
B3913_RS09680	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
B3913_RS09695	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
B3913_RS09695	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
B3913_RS09700	COG2224	Isocitrate lyase
B3913_RS09720	COG0559	Belongs to the binding-protein-dependent transport system permease family
B3913_RS09730	COG4638	Rieske (2fe-2S)
B3913_RS09740	COG1024	Enoyl-CoA hydratase
B3913_RS09750	COG0633	Ferredoxin
B3913_RS09755	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B3913_RS09770	COG0183	Belongs to the thiolase family
B3913_RS09780	COG4692	amylo-alpha-1,6-glucosidase activity
B3913_RS09785	COG0583	DNA-binding transcription factor activity
B3913_RS09810	COG2346	COG2346, Truncated hemoglobins
B3913_RS09935	COG2207	Transcriptional regulator
B3913_RS09980	COG1132	(ABC) transporter
B3913_RS10005	COG0659	secondary active sulfate transmembrane transporter activity
B3913_RS10035	COG2169	Transcriptional regulator
B3913_RS10040	COG5507	3-demethylubiquinone-9 3-methyltransferase
B3913_RS10045	COG0384	phenazine biosynthesis protein PhzF
B3913_RS10050	COG0583	DNA-binding transcription factor activity
B3913_RS10055	COG2733	membrane
B3913_RS10070	COG1012	belongs to the aldehyde dehydrogenase family
B3913_RS10075	COG3284	Transcriptional regulator
B3913_RS10090	COG1346	cytolysis
B3913_RS10095	COG1380	Effector of murein hydrolase LrgA
B3913_RS10100	COG4106	trans-aconitate 2-methyltransferase activity
B3913_RS10100	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
B3913_RS10110	COG0156	8-amino-7-oxononanoate synthase activity
B3913_RS10180	COG1131	(ABC) transporter
B3913_RS10185	COG0842	Transport permease protein
B3913_RS10190	COG0628	permease
B3913_RS10220	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B3913_RS10230	COG0828	Belongs to the bacterial ribosomal protein bS21 family
B3913_RS10235	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
B3913_RS10240	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
B3913_RS10245	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
B3913_RS10250	COG0330	HflC and HflK could
B3913_RS10255	COG0330	HflC and HflK could
B3913_RS10260	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
B3913_RS10265	COG1923	regulation of RNA biosynthetic process
B3913_RS10270	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
B3913_RS10275	COG1160	GTP binding
B3913_RS10280	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B3913_RS10285	COG2976	Protein conserved in bacteria
B3913_RS10290	COG0124	histidyl-tRNA synthetase
B3913_RS10295	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
B3913_RS10305	COG0820	rRNA (adenine-C2-)-methyltransferase activity
B3913_RS10310	COG0105	UTP biosynthetic process
B3913_RS10315	COG0525	valine-tRNA ligase activity
B3913_RS10330	COG0642	Histidine kinase
B3913_RS10350	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B3913_RS10355	COG0336	Belongs to the RNA methyltransferase TrmD family
B3913_RS10360	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
B3913_RS10365	COG0228	four-way junction DNA binding
B3913_RS10375	COG0425	Belongs to the sulfur carrier protein TusA family
B3913_RS10380	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
B3913_RS10425	COG0154	amidase activity
B3913_RS10430	COG4172	Belongs to the ABC transporter superfamily
B3913_RS10435	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B3913_RS10440	COG0601	transmembrane transport
B3913_RS10445	COG0747	negative chemotaxis
B3913_RS10470	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B3913_RS10480	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
B3913_RS10495	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
B3913_RS10500	COG3395	kinase activity
B3913_RS10515	COG1024	Enoyl-CoA hydratase
B3913_RS10535	COG0633	Ferredoxin
B3913_RS10540	COG0443	Heat shock 70 kDa protein
B3913_RS10545	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
B3913_RS10550	COG0316	Belongs to the HesB IscA family
B3913_RS10555	COG0822	iron-sulfur transferase activity
B3913_RS10560	COG1104	cysteine desulfurase activity
B3913_RS10570	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B3913_RS10575	COG0556	nucleotide-excision repair
B3913_RS10585	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
B3913_RS10590	COG3468	outer membrane autotransporter barrel domain protein
B3913_RS10615	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
B3913_RS10630	COG1960	acyl-CoA dehydrogenase activity
B3913_RS10635	COG1028	Short-chain dehydrogenase reductase Sdr
B3913_RS10640	COG0183	Belongs to the thiolase family
B3913_RS10650	COG1024	Enoyl-CoA hydratase
B3913_RS10665	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B3913_RS10670	COG0583	DNA-binding transcription factor activity
B3913_RS10675	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
B3913_RS10680	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
B3913_RS10685	COG0740	serine-type endopeptidase activity
B3913_RS10690	COG0544	peptidyl-prolyl cis-trans isomerase activity
B3913_RS10700	COG1278	Cold shock
B3913_RS10710	COG1278	Cold shock
B3913_RS10745	COG2171	N-acyltransferase activity
B3913_RS10750	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B3913_RS10755	COG2890	protein-(glutamine-N5) methyltransferase activity
B3913_RS10760	COG0488	(ABC) transporter
B3913_RS10765	COG4771	TonB-dependent receptor
B3913_RS10770	COG0210	DNA helicase
B3913_RS10790	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B3913_RS10790	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
B3913_RS10795	COG0196	riboflavin kinase activity
B3913_RS10800	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
B3913_RS10805	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
B3913_RS10810	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
B3913_RS10820	COG1522	sequence-specific DNA binding
B3913_RS10835	COG2951	lytic endotransglycosylase activity
B3913_RS10840	COG2833	Protein of unknown function (DUF455)
B3913_RS10860	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
B3913_RS10860	COG0189	ligase activity
B3913_RS10865	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
B3913_RS10865	COG1181	Belongs to the D-alanine--D-alanine ligase family
B3913_RS10870	COG3237	CsbD-like
B3913_RS10880	COG2823	Periplasmic or secreted lipoprotein
B3913_RS10895	COG4181	ATPase activity
B3913_RS10905	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B3913_RS10910	COG0584	glycerophosphoryl diester phosphodiesterase
B3913_RS10915	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
B3913_RS10925	COG0678	peroxiredoxin activity
B3913_RS10925	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
B3913_RS10935	COG0789	Transcriptional regulator
B3913_RS10940	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
B3913_RS10970	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
B3913_RS10975	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
B3913_RS10985	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
B3913_RS10990	COG2252	PERMEase
B3913_RS11000	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B3913_RS11030	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B3913_RS11035	COG2358	TRAP transporter, solute receptor (TAXI family
B3913_RS11065	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B3913_RS11070	COG1366	Belongs to the anti-sigma-factor antagonist family
B3913_RS11075	COG2172	sigma factor antagonist activity
B3913_RS11080	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
B3913_RS11090	COG2208	phosphoserine phosphatase activity
B3913_RS11090	COG2770	Histidine kinase
B3913_RS11115	COG1595	DNA-templated transcription, initiation
B3913_RS11130	COG4792	protein secretion
B3913_RS11135	COG4791	protein targeting
B3913_RS11140	COG4794	Type iii secretion
B3913_RS11145	COG4790	Type iii secretion
B3913_RS11180	COG4669	(LipO)protein
B3913_RS11245	COG4789	Type iii secretion
B3913_RS11275	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B3913_RS11280	COG0840	transmembrane signaling receptor activity
B3913_RS11285	COG2233	PERMEase
B3913_RS11305	COG0492	ferredoxin-NADP+ reductase activity
B3913_RS11310	COG1840	ABC-type Fe3 transport system, periplasmic component
B3913_RS11315	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B3913_RS11320	COG1178	ABC-type Fe3 transport system permease component
B3913_RS11325	COG3842	ATPase activity
B3913_RS11330	COG0583	DNA-binding transcription factor activity
B3913_RS11350	COG0501	Belongs to the peptidase M48B family
B3913_RS11360	COG0697	spore germination
B3913_RS11370	COG1846	Transcriptional regulator
B3913_RS11380	COG1566	PFAM secretion protein HlyD family protein
B3913_RS11385	COG2814	Major facilitator Superfamily
B3913_RS11390	COG0473	3-isopropylmalate dehydrogenase activity
B3913_RS11400	COG0747	negative chemotaxis
B3913_RS11410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B3913_RS11425	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
B3913_RS11450	COG1012	belongs to the aldehyde dehydrogenase family
B3913_RS11460	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B3913_RS11465	COG1115	amino acid carrier protein
B3913_RS11470	COG0433	COG0433 Predicted ATPase
B3913_RS11475	COG0217	transcriptional regulatory protein
B3913_RS11480	COG0151	Belongs to the GarS family
B3913_RS11485	COG0408	coproporphyrinogen oxidase activity
B3913_RS11490	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
B3913_RS11495	COG0799	negative regulation of ribosome biogenesis
B3913_RS11500	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
B3913_RS11505	COG0424	maF-like protein
B3913_RS11510	COG3468	outer membrane autotransporter barrel domain protein
B3913_RS11550	COG1530	ribonuclease E activity
B3913_RS11555	COG0077	Prephenate dehydratase
B3913_RS11570	COG1132	(ABC) transporter
B3913_RS11575	COG0859	PFAM glycosyl transferase family 9
B3913_RS11605	COG2194	sulfuric ester hydrolase activity
B3913_RS11610	COG0438	transferase activity, transferring glycosyl groups
B3913_RS11615	COG0463	Glycosyl transferase, family 2
B3913_RS11620	COG0726	polysaccharide deacetylase
B3913_RS11625	COG0438	transferase activity, transferring glycosyl groups
B3913_RS11640	COG1643	Atp-dependent helicase
B3913_RS11645	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
B3913_RS11645	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
B3913_RS11650	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
B3913_RS11660	COG0704	Plays a role in the regulation of phosphate uptake
B3913_RS11665	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
B3913_RS11670	COG1960	acyl-CoA dehydrogenase activity
B3913_RS11695	COG1177	transmembrane transport
B3913_RS11700	COG1176	ABC-type spermidine putrescine transport system, permease component I
B3913_RS11705	COG3842	ATPase activity
B3913_RS11710	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
B3913_RS11725	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
B3913_RS11730	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B3913_RS11740	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
B3913_RS11740	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
B3913_RS11760	COG0372	Belongs to the citrate synthase family
B3913_RS11765	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
B3913_RS11770	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
B3913_RS11775	COG1053	succinate dehydrogenase
B3913_RS11780	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
B3913_RS11785	COG2009	succinate dehydrogenase
B3913_RS11790	COG2188	Transcriptional regulator
B3913_RS11795	COG0039	L-malate dehydrogenase activity
B3913_RS11825	COG1981	membrane
B3913_RS11850	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B3913_RS11860	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
B3913_RS11890	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
B3913_RS11895	COG0148	phosphopyruvate hydratase activity
B3913_RS11905	COG2877	3-deoxy-8-phosphooctulonate synthase activity
B3913_RS11910	COG0504	CTP synthase activity
B3913_RS11935	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B3913_RS11945	COG0747	negative chemotaxis
B3913_RS11950	COG4172	Belongs to the ABC transporter superfamily
B3913_RS11955	COG1446	asparaginase
B3913_RS11985	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
B3913_RS12000	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
B3913_RS12005	COG0697	spore germination
B3913_RS12010	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B3913_RS12020	COG3193	protein, possibly involved in utilization of glycolate and propanediol
B3913_RS12025	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B3913_RS12030	COG0791	NLP P60 protein
B3913_RS12045	COG0583	DNA-binding transcription factor activity
B3913_RS12060	COG0583	DNA-binding transcription factor activity
B3913_RS12070	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
B3913_RS12085	COG0670	Belongs to the BI1 family
B3913_RS12090	COG3181	Tripartite tricarboxylate transporter family receptor
B3913_RS12105	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B3913_RS12115	COG1381	Involved in DNA repair and RecF pathway recombination
B3913_RS12120	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
B3913_RS12125	COG0571	ribonuclease III activity
B3913_RS12130	COG0681	Belongs to the peptidase S26 family
B3913_RS12135	COG0481	GTPase activity
B3913_RS12140	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B3913_RS12165	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B3913_RS12170	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B3913_RS12185	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B3913_RS12190	COG0416	fatty acid biosynthetic process
B3913_RS12195	COG0333	Belongs to the bacterial ribosomal protein bL32 family
B3913_RS12200	COG1399	metal-binding, possibly nucleic acid-binding protein
B3913_RS12205	COG0424	maF-like protein
B3913_RS12215	COG3023	N-Acetylmuramoyl-L-alanine amidase
B3913_RS12220	COG1289	transmembrane transporter activity
B3913_RS12230	COG3022	response to hydroperoxide
B3913_RS12240	COG1028	Short-chain dehydrogenase reductase Sdr
B3913_RS12255	COG3486	L-lysine 6-monooxygenase (NADPH) activity
B3913_RS12285	COG2814	Major facilitator Superfamily
B3913_RS12305	COG3706	GGDEF domain
B3913_RS12330	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
B3913_RS12335	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
B3913_RS12340	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
B3913_RS12345	COG1674	ftsk spoiiie
B3913_RS12350	COG0492	ferredoxin-NADP+ reductase activity
B3913_RS12355	COG1193	negative regulation of DNA recombination
B3913_RS12375	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B3913_RS12385	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
B3913_RS12390	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
B3913_RS12395	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
B3913_RS12400	COG2205	protein histidine kinase activity
B3913_RS12405	COG0745	RESPONSE REGULATOR receiver
B3913_RS12450	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B3913_RS12470	COG0612	Peptidase, M16
B3913_RS12480	COG0443	Heat shock 70 kDa protein
B3913_RS12490	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
B3913_RS12500	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
B3913_RS12505	COG1420	regulation of RNA biosynthetic process
B3913_RS12510	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
B3913_RS12515	COG0497	DNA recombination
B3913_RS12520	COG0735	belongs to the Fur family
B3913_RS12525	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B3913_RS12530	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
B3913_RS12535	COG0812	UDP-N-acetylmuramate dehydrogenase activity
B3913_RS12570	COG0404	The glycine cleavage system catalyzes the degradation of glycine
B3913_RS12570	COG0446	pyridine nucleotide-disulphide oxidoreductase
B3913_RS12575	COG4311	Sarcosine oxidase, delta subunit
B3913_RS12580	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B3913_RS12590	COG0583	DNA-binding transcription factor activity
B3913_RS12600	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
B3913_RS12630	COG4964	Belongs to the GSP D family
B3913_RS12690	COG0181	hydroxymethylbilane synthase activity
B3913_RS12695	COG0861	Integral membrane protein TerC family
B3913_RS12700	COG0861	Integral membrane protein TerC family
B3913_RS12705	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
B3913_RS12710	COG0045	succinate-CoA ligase (ADP-forming) activity
B3913_RS12720	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
B3913_RS12730	COG2137	regulation of response to DNA damage stimulus
B3913_RS12735	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
B3913_RS12755	COG1024	Enoyl-CoA hydratase
B3913_RS12755	COG1250	3-hydroxyacyl-CoA dehydrogenase
B3913_RS12760	COG3842	ATPase activity
B3913_RS12775	COG1028	Short-chain dehydrogenase reductase Sdr
B3913_RS12795	COG0583	DNA-binding transcription factor activity
B3913_RS12800	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B3913_RS12810	COG2974	May be involved in recombination
B3913_RS12815	COG0540	Belongs to the ATCase OTCase family
B3913_RS12885	COG0776	regulation of translation
B3913_RS12890	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B3913_RS12890	COG0072	phenylalanine-tRNA ligase activity
B3913_RS12895	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
B3913_RS12900	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
B3913_RS12905	COG0291	Belongs to the bacterial ribosomal protein bL35 family
B3913_RS12915	COG0756	dUTP diphosphatase activity
B3913_RS12925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B3913_RS12940	COG0500	methyltransferase
B3913_RS12950	COG0586	Pfam SNARE associated Golgi protein
B3913_RS12975	COG1609	Transcriptional regulator
B3913_RS12980	COG4172	Belongs to the ABC transporter superfamily
B3913_RS12985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B3913_RS12990	COG0601	transmembrane transport
B3913_RS12995	COG0747	negative chemotaxis
B3913_RS13010	COG1280	lysine exporter protein (LysE YggA)
B3913_RS13025	COG2814	Major facilitator Superfamily
B3913_RS13055	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
B3913_RS13070	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
B3913_RS13105	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B3913_RS13110	COG1116	anion transmembrane transporter activity
B3913_RS13120	COG1228	amidohydrolase
B3913_RS13135	COG0477	Major facilitator Superfamily
B3913_RS13145	COG3550	peptidyl-serine autophosphorylation
B3913_RS13155	COG0518	GMP synthase (glutamine-hydrolyzing) activity
B3913_RS13155	COG0519	Catalyzes the synthesis of GMP from XMP
B3913_RS13180	COG2197	response regulator
B3913_RS13205	COG0420	3'-5' exonuclease activity
B3913_RS13210	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B3913_RS13240	COG0395	ABC-type sugar transport system, permease component
B3913_RS13250	COG3842	ATPase activity
B3913_RS13280	COG3181	Tripartite tricarboxylate transporter family receptor
B3913_RS13315	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B3913_RS13340	COG0602	queuosine metabolic process
B3913_RS13345	COG0720	synthase
B3913_RS13350	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
B3913_RS13355	COG0235	Class ii aldolase
B3913_RS13380	COG3064	Membrane
B3913_RS13380	COG3210	domain, Protein
B3913_RS13380	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
B3913_RS13385	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
B3913_RS13385	COG0047	phosphoribosylformylglycinamidine synthase activity
B3913_RS13390	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
B3913_RS13395	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
B3913_RS13395	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
B3913_RS13400	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B3913_RS13415	COG3539	Fimbrial protein
B3913_RS13425	COG2050	protein possibly involved in aromatic compounds catabolism
B3913_RS13430	COG1024	Enoyl-CoA hydratase
B3913_RS13435	COG1012	belongs to the aldehyde dehydrogenase family
B3913_RS13445	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B3913_RS13450	COG2151	metal-sulfur cluster biosynthetic enzyme
B3913_RS13455	COG3396	Phenylacetate-CoA oxygenase
B3913_RS13460	COG3460	Phenylacetate-CoA oxygenase
B3913_RS13465	COG3396	Phenylacetate-CoA oxygenase
B3913_RS13470	COG3327	negative regulation of DNA-templated transcription, initiation
B3913_RS13480	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
B3913_RS13485	COG0501	Belongs to the peptidase M48B family
B3913_RS13490	COG1162	GTPase activity
B3913_RS13495	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B3913_RS13500	COG0601	transmembrane transport
B3913_RS13505	COG0747	negative chemotaxis
B3913_RS13550	COG0668	transmembrane transport
B3913_RS13555	COG0165	Argininosuccinate lyase
B3913_RS13575	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
B3913_RS13580	COG0303	'Molybdopterin
B3913_RS13585	COG0521	Mo-molybdopterin cofactor biosynthetic process
B3913_RS13600	COG0315	cyclic pyranopterin monophosphate synthase activity
B3913_RS13610	COG0412	Dienelactone hydrolase
B3913_RS13620	COG0678	peroxiredoxin activity
B3913_RS13630	COG0697	spore germination
B3913_RS13635	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
B3913_RS13660	COG0789	Transcriptional regulator
B3913_RS13680	COG1028	Short-chain dehydrogenase reductase Sdr
B3913_RS13690	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
B3913_RS13695	COG1845	cytochrome c oxidase, subunit III
B3913_RS13700	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B3913_RS13710	COG0477	Major facilitator Superfamily
B3913_RS13740	COG3468	outer membrane autotransporter barrel domain protein
B3913_RS13750	COG1309	transcriptional regulator
B3913_RS13755	COG2271	Major facilitator Superfamily
B3913_RS13790	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
B3913_RS13790	COG0506	proline dehydrogenase activity
B3913_RS13790	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
B3913_RS13800	COG3008	intermembrane lipid transfer
B3913_RS13800	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
B3913_RS13805	COG2995	paraquat-inducible protein a
B3913_RS13810	COG0542	response to heat
B3913_RS13815	COG4953	penicillin-binding protein 1C
B3913_RS13825	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
B3913_RS13830	COG1278	Cold shock
B3913_RS13840	COG0183	Belongs to the thiolase family
B3913_RS13845	COG0038	chloride channel
B3913_RS13850	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
B3913_RS13855	COG1570	exodeoxyribonuclease VII activity
B3913_RS13865	COG0811	peptide transport
B3913_RS13870	COG0848	biopolymer transport protein
B3913_RS13875	COG1663	tetraacyldisaccharide 4'-kinase activity
B3913_RS13880	COG2835	tetraacyldisaccharide 4'-kinase activity
B3913_RS13885	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
B3913_RS13890	COG0563	adenylate kinase activity
B3913_RS13900	COG0728	peptidoglycan biosynthetic process
B3913_RS13910	COG0268	Binds directly to 16S ribosomal RNA
B3913_RS13940	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
B3913_RS13965	COG0436	Aminotransferase
B3913_RS13970	COG3737	Protein of unknown function (DUF498/DUF598)
B3913_RS13975	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
B3913_RS13980	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
B3913_RS13985	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
B3913_RS13995	COG0305	Participates in initiation and elongation during chromosome replication
B3913_RS14005	COG0359	binds to the 23S rRNA
B3913_RS14010	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
B3913_RS14015	COG2965	DNA replication, synthesis of RNA primer
B3913_RS14020	COG0360	Binds together with S18 to 16S ribosomal RNA
B3913_RS14025	COG1469	GTP cyclohydrolase I activity
B3913_RS14030	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
B3913_RS14035	COG0142	geranyltranstransferase activity
B3913_RS14040	COG1722	exodeoxyribonuclease VII activity
B3913_RS14050	COG3181	Tripartite tricarboxylate transporter family receptor
B3913_RS14070	COG2239	Acts as a magnesium transporter
B3913_RS14080	COG2855	membrane
B3913_RS14090	COG1473	amidohydrolase
B3913_RS14095	COG0318	PFAM AMP-dependent synthetase and ligase
B3913_RS14115	COG1501	Belongs to the glycosyl hydrolase 31 family
B3913_RS14120	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
B3913_RS14125	COG2011	ABC-type metal ion transport system permease component
B3913_RS14145	COG1454	alcohol dehydrogenase
B3913_RS14170	COG2186	Transcriptional regulator
B3913_RS14175	COG3181	Tripartite tricarboxylate transporter family receptor
B3913_RS14195	COG1175	transmembrane transport
B3913_RS14200	COG0395	ABC-type sugar transport system, permease component
B3913_RS14205	COG3842	ATPase activity
B3913_RS14210	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B3913_RS14220	COG1653	transport
B3913_RS14240	COG2818	Glycosylase
B3913_RS14245	COG2982	Protein involved in outer membrane biogenesis
B3913_RS14255	COG1309	transcriptional regulator
B3913_RS14260	COG1028	Short-chain dehydrogenase reductase Sdr
B3913_RS14300	COG0583	DNA-binding transcription factor activity
B3913_RS14305	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
B3913_RS14310	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
B3913_RS14325	COG1028	Short-chain dehydrogenase reductase Sdr
B3913_RS14330	COG0477	Major facilitator Superfamily
B3913_RS14340	COG0583	DNA-binding transcription factor activity
B3913_RS14345	COG1448	Aminotransferase
B3913_RS14350	COG1418	mRNA catabolic process
B3913_RS14375	COG1063	alcohol dehydrogenase
B3913_RS14395	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B3913_RS14405	COG0318	PFAM AMP-dependent synthetase and ligase
B3913_RS14415	COG1522	sequence-specific DNA binding
B3913_RS14420	COG3181	Tripartite tricarboxylate transporter family receptor
B3913_RS14425	COG0307	riboflavin synthase, alpha
B3913_RS14430	COG0154	amidase activity
B3913_RS14450	COG2807	transmembrane transport
B3913_RS14455	COG0590	tRNA wobble adenosine to inosine editing
B3913_RS14465	COG0583	DNA-binding transcription factor activity
B3913_RS14480	COG1902	pentaerythritol trinitrate reductase activity
B3913_RS14500	COG0559	Belongs to the binding-protein-dependent transport system permease family
B3913_RS14505	COG0251	oxidation-reduction process
B3913_RS14510	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B3913_RS14520	COG1414	Transcriptional regulator
B3913_RS14525	COG1028	Short-chain dehydrogenase reductase Sdr
B3913_RS14540	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B3913_RS14555	COG1024	Enoyl-CoA hydratase
B3913_RS14560	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B3913_RS14565	COG0154	amidase activity
B3913_RS14605	COG3909	cytochrome
B3913_RS14610	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
B3913_RS14615	COG0625	glutathione transferase activity
B3913_RS14620	COG0730	response to heat
B3913_RS14625	COG0482	sulfurtransferase activity
B3913_RS14630	COG0583	DNA-binding transcription factor activity
B3913_RS14665	COG2819	hydrolase of the alpha beta superfamily
B3913_RS14670	COG0247	lactate metabolic process
B3913_RS14675	COG0277	FAD linked oxidase domain protein
B3913_RS14680	COG0277	FAD linked oxidase domain protein
B3913_RS14685	COG0277	FAD linked oxidase domain protein
B3913_RS14690	COG3064	Membrane
B3913_RS14690	COG3210	domain, Protein
B3913_RS14690	COG3210	domain, Protein
B3913_RS14690	COG3064	Membrane
B3913_RS14690	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
B3913_RS14690	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
B3913_RS14695	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
B3913_RS14700	COG0312	modulator of DNA gyrase
B3913_RS14735	COG1666	GTP binding
B3913_RS14780	COG3220	belongs to the UPF0276 family
B3913_RS14800	COG0640	Transcriptional regulator
B3913_RS14805	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
B3913_RS14810	COG1845	cytochrome c oxidase, subunit III
B3913_RS14815	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B3913_RS14825	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
B3913_RS14860	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B3913_RS14865	COG0583	DNA-binding transcription factor activity
B3913_RS14895	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B3913_RS14895	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B3913_RS14910	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
B3913_RS14915	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
B3913_RS14925	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
B3913_RS14940	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
B3913_RS14945	COG0316	Belongs to the HesB IscA family
B3913_RS14955	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
B3913_RS14960	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
B3913_RS14965	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
B3913_RS14970	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
B3913_RS14975	COG0312	modulator of DNA gyrase
B3913_RS14980	COG3028	Belongs to the UPF0307 family
B3913_RS14995	COG1116	anion transmembrane transporter activity
B3913_RS15000	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B3913_RS15005	COG1335	isochorismatase
B3913_RS15010	COG0346	lactoylglutathione lyase activity
B3913_RS15015	COG0513	Belongs to the DEAD box helicase family
B3913_RS15020	COG3069	C4-dicarboxylate transmembrane transporter activity
B3913_RS15025	COG1802	Transcriptional regulator
B3913_RS15035	COG1042	CoA-binding domain protein
B3913_RS15035	COG0045	succinate-CoA ligase (ADP-forming) activity
B3913_RS15035	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B3913_RS15040	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
B3913_RS15055	COG1522	sequence-specific DNA binding
B3913_RS15090	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B3913_RS15095	COG1696	Membrane protein involved in D-alanine export
B3913_RS15120	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B3913_RS15130	COG2264	protein methyltransferase activity
B3913_RS15135	COG0439	Biotin carboxylase
B3913_RS15140	COG0511	ligase activity, forming carbon-carbon bonds
B3913_RS15145	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
B3913_RS15150	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B3913_RS15155	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
B3913_RS15160	COG3150	esterase
B3913_RS15165	COG0557	exoribonuclease II activity
B3913_RS15175	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
B3913_RS15195	COG1522	sequence-specific DNA binding
B3913_RS15200	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B3913_RS15205	COG1028	Short-chain dehydrogenase reductase Sdr
B3913_RS15225	COG0653	protein targeting
B3913_RS15230	COG0739	heme binding
B3913_RS15240	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
B3913_RS15245	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
B3913_RS15255	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
B3913_RS15260	COG1181	Belongs to the D-alanine--D-alanine ligase family
B3913_RS15265	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
B3913_RS15270	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
B3913_RS15280	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
B3913_RS15285	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B3913_RS15290	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
B3913_RS15300	COG3116	cell division
B3913_RS15305	COG0275	rRNA processing
B3913_RS15310	COG2001	Belongs to the MraZ family
B3913_RS15315	COG0488	(ABC) transporter
B3913_RS15320	COG0418	dihydroorotase activity
B3913_RS15325	COG1473	amidohydrolase
B3913_RS15375	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B3913_RS15380	COG4654	Cytochrome c, class I
B3913_RS15385	COG0129	dihydroxy-acid dehydratase activity
B3913_RS15390	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
B3913_RS15440	COG2084	Dehydrogenase
B3913_RS15445	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
B3913_RS15460	COG2096	Adenosyltransferase
B3913_RS15470	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
B3913_RS15475	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
B3913_RS15485	COG0523	cobalamin synthesis protein
B3913_RS15490	COG0735	belongs to the Fur family
B3913_RS15510	COG0803	Belongs to the bacterial solute-binding protein 9 family
B3913_RS15520	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
B3913_RS15530	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
B3913_RS15540	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
B3913_RS15545	COG1560	Kdo2-lipid A biosynthetic process
B3913_RS15555	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
B3913_RS15570	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
B3913_RS15575	COG1950	PFAM Membrane protein of
B3913_RS15590	COG0583	DNA-binding transcription factor activity
B3913_RS15600	COG0477	Major facilitator Superfamily
B3913_RS15615	COG0617	tRNA 3'-terminal CCA addition
B3913_RS15625	COG0513	Belongs to the DEAD box helicase family
B3913_RS15630	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
B3913_RS15640	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B3913_RS15645	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
B3913_RS15710	COG1280	lysine exporter protein (LysE YggA)
B3913_RS15725	COG0405	Gamma-glutamyltransferase
B3913_RS15735	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B3913_RS15760	COG1309	transcriptional regulator
B3913_RS15775	COG0745	RESPONSE REGULATOR receiver
B3913_RS15820	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
B3913_RS15840	COG0582	viral genome integration into host DNA
B3913_RS15845	COG0012	GTP binding
B3913_RS15855	COG0193	aminoacyl-tRNA hydrolase activity
B3913_RS15860	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
B3913_RS15865	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
B3913_RS15875	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
B3913_RS15880	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
B3913_RS15890	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
B3913_RS15915	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
B3913_RS15925	COG1368	sulfuric ester hydrolase activity
B3913_RS15930	COG0642	Histidine kinase
B3913_RS15935	COG0745	RESPONSE REGULATOR receiver
B3913_RS15940	COG0277	FAD linked oxidase domain protein
B3913_RS15955	COG0166	Belongs to the GPI family
B3913_RS15960	COG0438	transferase activity, transferring glycosyl groups
B3913_RS15965	COG0438	transferase activity, transferring glycosyl groups
B3913_RS15980	COG0438	transferase activity, transferring glycosyl groups
B3913_RS15995	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
B3913_RS16000	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B3913_RS16005	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
B3913_RS16015	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
B3913_RS16025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B3913_RS16030	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B3913_RS16040	COG0747	negative chemotaxis
B3913_RS16045	COG0601	transmembrane transport
B3913_RS16050	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B3913_RS16070	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
B3913_RS16075	COG0830	nickel cation binding
B3913_RS16085	COG0804	urea catabolic process
B3913_RS16090	COG0832	Belongs to the urease beta subunit family
B3913_RS16100	COG0831	urea catabolic process
B3913_RS16105	COG0829	nickel cation binding
B3913_RS16115	COG0633	Ferredoxin
B3913_RS16130	COG2188	Transcriptional regulator
B3913_RS16155	COG2719	SpoVR family
B3913_RS16160	COG2718	Belongs to the UPF0229 family
B3913_RS16175	COG1028	Short-chain dehydrogenase reductase Sdr
B3913_RS16180	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B3913_RS16195	COG1960	acyl-CoA dehydrogenase activity
B3913_RS16240	COG0183	Belongs to the thiolase family
B3913_RS16245	COG2030	dehydratase
B3913_RS16290	COG0328	RNA-DNA hybrid ribonuclease activity
B3913_RS16295	COG2226	methyltransferase
B3913_RS16300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B3913_RS16305	COG0741	lytic transglycosylase activity
B3913_RS16305	COG1388	LysM domain
B3913_RS16325	COG2979	Protein of unknown function (DUF533)
B3913_RS16360	COG1271	oxidase subunit
B3913_RS16365	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
B3913_RS16370	COG0850	regulation of cytokinetic process
B3913_RS16375	COG2894	cell division
B3913_RS16380	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
B3913_RS16400	COG0488	(ABC) transporter
B3913_RS16410	COG0601	transmembrane transport
B3913_RS16420	COG1215	transferase activity, transferring glycosyl groups
B3913_RS16435	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
B3913_RS16445	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B3913_RS16465	COG0318	PFAM AMP-dependent synthetase and ligase
B3913_RS16470	COG2188	Transcriptional regulator
B3913_RS16475	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
B3913_RS16480	COG2814	Major facilitator Superfamily
B3913_RS16490	COG0259	pyridoxamine-phosphate oxidase activity
B3913_RS16495	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B3913_RS16510	COG0583	DNA-binding transcription factor activity
B3913_RS16515	COG1960	acyl-CoA dehydrogenase activity
B3913_RS16540	COG0134	indole-3-glycerol-phosphate synthase activity
B3913_RS16545	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
B3913_RS16550	COG0512	Glutamine amidotransferase of anthranilate synthase
B3913_RS16560	COG0546	phosphoglycolate phosphatase activity
B3913_RS16565	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
B3913_RS16570	COG2967	ApaG domain
B3913_RS16575	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
B3913_RS16580	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B3913_RS16585	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
B3913_RS16590	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B3913_RS16600	COG0037	tRNA processing
B3913_RS16610	COG3634	alkyl hydroperoxide reductase activity
B3913_RS16615	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B3913_RS16620	COG1024	Enoyl-CoA hydratase
B3913_RS16645	COG0356	it plays a direct role in the translocation of protons across the membrane
B3913_RS16655	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
B3913_RS16660	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
B3913_RS16665	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
B3913_RS16670	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
B3913_RS16675	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
B3913_RS16680	COG0355	proton-transporting ATP synthase activity, rotational mechanism
B3913_RS16690	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
B3913_RS16695	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
B3913_RS16700	COG0210	DNA helicase
B3913_RS16710	COG2195	Cleaves the N-terminal amino acid of tripeptides
B3913_RS16720	COG4172	Belongs to the ABC transporter superfamily
B3913_RS16725	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B3913_RS16730	COG0601	transmembrane transport
B3913_RS16750	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
B3913_RS16755	COG1024	Enoyl-CoA hydratase
B3913_RS16760	COG1024	Enoyl-CoA hydratase
B3913_RS16785	COG1250	3-hydroxyacyl-CoA dehydrogenase
B3913_RS16815	COG2132	Multicopper oxidase
B3913_RS16825	COG1250	3-hydroxyacyl-CoA dehydrogenase
B3913_RS16825	COG1024	Enoyl-CoA hydratase
B3913_RS16840	COG1414	Transcriptional regulator
B3913_RS16850	COG0154	amidase activity
B3913_RS16880	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B3913_RS16885	COG3568	Endonuclease Exonuclease Phosphatase
B3913_RS16890	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
B3913_RS16920	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
B3913_RS16930	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
B3913_RS16945	COG1137	ATPase activity
B3913_RS16960	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
B3913_RS16965	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B3913_RS16965	COG2010	Cytochrome c
B3913_RS16975	COG1660	Displays ATPase and GTPase activities
B3913_RS16980	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
B3913_RS17020	COG3181	Tripartite tricarboxylate transporter family receptor
B3913_RS17030	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
B3913_RS17035	COG2890	protein-(glutamine-N5) methyltransferase activity
B3913_RS17040	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
B3913_RS17045	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
B3913_RS17090	COG1960	acyl-CoA dehydrogenase activity
B3913_RS17100	COG0183	Belongs to the thiolase family
B3913_RS17105	COG1522	sequence-specific DNA binding
B3913_RS17110	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B3913_RS17130	COG1024	Enoyl-CoA hydratase
B3913_RS17145	COG0604	alcohol dehydrogenase
B3913_RS17165	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B3913_RS17175	COG1960	acyl-CoA dehydrogenase activity
B3913_RS17180	COG1960	acyl-CoA dehydrogenase activity
B3913_RS17185	COG0277	FAD linked oxidase domain protein
B3913_RS17195	COG3181	Tripartite tricarboxylate transporter family receptor
B3913_RS17215	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B3913_RS17225	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B3913_RS17230	COG3181	Tripartite tricarboxylate transporter family receptor
B3913_RS17235	COG1960	acyl-CoA dehydrogenase activity
B3913_RS17255	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B3913_RS17260	COG1024	Enoyl-CoA hydratase
B3913_RS17265	COG1960	acyl-CoA dehydrogenase activity
B3913_RS17285	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
B3913_RS17290	COG0022	dehydrogenase e1 component
B3913_RS17295	COG1024	Enoyl-CoA hydratase
B3913_RS17300	COG0508	dehydrogenase complex catalyzes the overall conversion of
B3913_RS17320	COG0683	leucine binding
B3913_RS17325	COG0559	Belongs to the binding-protein-dependent transport system permease family
B3913_RS17330	COG0411	ABC transporter
B3913_RS17340	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B3913_RS17355	COG3181	Tripartite tricarboxylate transporter family receptor
B3913_RS17380	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
B3913_RS17385	COG0793	Belongs to the peptidase S41A family
B3913_RS17390	COG4942	peptidase
B3913_RS17395	COG0588	phosphoglycerate mutase activity
B3913_RS17400	COG1054	Belongs to the UPF0176 family
B3913_RS17405	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
B3913_RS17410	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
B3913_RS17415	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
B3913_RS17420	COG3181	Tripartite tricarboxylate transporter family receptor
B3913_RS17435	COG2226	methyltransferase
B3913_RS17440	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
B3913_RS17455	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B3913_RS17460	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
B3913_RS17485	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
B3913_RS17510	COG1335	isochorismatase
B3913_RS17515	COG2309	aminopeptidase activity
B3913_RS17520	COG0596	Alpha beta hydrolase
B3913_RS17525	COG3473	Maleate cis-trans isomerase
B3913_RS17535	COG2068	MobA-Related Protein
B3913_RS17560	COG2204	response regulator
B3913_RS17565	COG5000	phosphorelay sensor kinase activity
B3913_RS17575	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B3913_RS17575	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
B3913_RS17585	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
B3913_RS17610	COG0583	DNA-binding transcription factor activity
B3913_RS17625	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
B3913_RS17630	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B3913_RS17635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B3913_RS17650	COG0758	DNA mediated transformation
B3913_RS17655	COG1522	sequence-specific DNA binding
B3913_RS17665	COG0242	peptide deformylase activity
B3913_RS17675	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
B3913_RS17685	COG0546	phosphoglycolate phosphatase activity
B3913_RS17705	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
B3913_RS17710	COG1942	4-Oxalocrotonate Tautomerase
B3913_RS17715	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B3913_RS17735	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B3913_RS17755	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B3913_RS17760	COG1024	Enoyl-CoA hydratase
B3913_RS17765	COG1414	Transcriptional regulator
B3913_RS17770	COG0318	PFAM AMP-dependent synthetase and ligase
B3913_RS17775	COG3181	Tripartite tricarboxylate transporter family receptor
B3913_RS17805	COG0583	DNA-binding transcription factor activity
B3913_RS17820	COG3422	double-strand break repair
B3913_RS17825	COG0330	HflC and HflK could
B3913_RS17835	COG0251	oxidation-reduction process
B3913_RS17880	COG3723	Recombinational DNA repair protein, rece pathway
B3913_RS17915	COG0582	viral genome integration into host DNA
B3913_RS17940	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
B3913_RS17950	COG0706	membrane insertase activity
B3913_RS17955	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
B3913_RS17960	COG0594	ribonuclease P activity
B3913_RS17965	COG0230	Belongs to the bacterial ribosomal protein bL34 family
B3913_RS17970	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
B3913_RS17985	COG1414	Transcriptional regulator
B3913_RS17990	COG0154	amidase activity
B3913_RS18005	COG1304	FMN binding
B3913_RS18025	COG1960	acyl-CoA dehydrogenase activity
B3913_RS18045	COG1960	acyl-CoA dehydrogenase activity
B3913_RS18055	COG0183	Belongs to the thiolase family
B3913_RS18060	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B3913_RS18075	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B3913_RS18080	COG3181	Tripartite tricarboxylate transporter family receptor
B3913_RS18090	COG2358	TRAP transporter, solute receptor (TAXI family
B3913_RS18100	COG1629	transport
B3913_RS18105	COG2922	Belongs to the Smg family
B3913_RS18130	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
B3913_RS18135	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B3913_RS18140	COG1028	Short-chain dehydrogenase reductase Sdr
B3913_RS18145	COG1012	belongs to the aldehyde dehydrogenase family
B3913_RS18155	COG0028	Belongs to the TPP enzyme family
B3913_RS18160	COG1522	sequence-specific DNA binding
B3913_RS18165	COG3781	membrane
B3913_RS18175	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
B3913_RS18195	COG4206	TonB-dependent receptor
B3913_RS18200	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B3913_RS18205	COG2022	thiamine diphosphate biosynthetic process
B3913_RS18210	COG0351	phosphomethylpyrimidine kinase
B3913_RS18215	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
B3913_RS18230	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
B3913_RS18240	COG0628	permease
B3913_RS18250	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
B3913_RS18260	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
B3913_RS18265	COG0049	tRNA binding
B3913_RS18270	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
B3913_RS18275	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
B3913_RS18280	COG0051	transcription antitermination factor activity, RNA binding
B3913_RS18285	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
B3913_RS18290	COG0088	Forms part of the polypeptide exit tunnel
B3913_RS18295	COG0089	rRNA binding
B3913_RS18300	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
B3913_RS18305	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
B3913_RS18310	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
B3913_RS18315	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
B3913_RS18320	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
B3913_RS18325	COG0255	Belongs to the universal ribosomal protein uL29 family
B3913_RS18330	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
B3913_RS18350	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
B3913_RS18355	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
B3913_RS18360	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
B3913_RS18365	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
B3913_RS18370	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
B3913_RS18375	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
B3913_RS18380	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
B3913_RS18385	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
B3913_RS18390	COG1841	ribosomal large subunit assembly
B3913_RS18395	COG0200	Binds to the 23S rRNA
B3913_RS18400	COG0201	protein transport
B3913_RS18405	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
B3913_RS18410	COG0257	Belongs to the bacterial ribosomal protein bL36 family
B3913_RS18415	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
B3913_RS18420	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
B3913_RS18425	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
B3913_RS18430	COG0202	RNA polymerase activity
B3913_RS18435	COG0203	ribosomal protein L17
B3913_RS18445	COG1324	tolerance protein
B3913_RS18450	COG4232	protein-disulfide reductase activity
B3913_RS18465	COG0218	Necessary for normal cell division and for the maintenance of normal septation
B3913_RS18475	COG1333	cytochrome c biogenesis protein
B3913_RS18480	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B3913_RS18490	COG1965	Belongs to the frataxin family
B3913_RS18500	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
B3913_RS18505	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
B3913_RS18510	COG0232	Belongs to the dGTPase family. Type 2 subfamily
B3913_RS18525	COG2814	Major facilitator Superfamily
B3913_RS18530	COG0629	single-stranded DNA binding
B3913_RS18570	COG0402	S-adenosylhomocysteine deaminase activity
B3913_RS18580	COG0438	transferase activity, transferring glycosyl groups
B3913_RS18600	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B3913_RS18625	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
B3913_RS18630	COG2186	Transcriptional regulator
B3913_RS18650	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B3913_RS18655	COG1956	GAF domain-containing protein
B3913_RS18660	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B3913_RS18670	COG1652	LysM domain
B3913_RS18685	COG0220	tRNA (guanine-N7-)-methyltransferase activity
B3913_RS18700	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B3913_RS18725	COG3181	Tripartite tricarboxylate transporter family receptor
B3913_RS18740	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B3913_RS18755	COG1024	Enoyl-CoA hydratase
B3913_RS18770	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B3913_RS18775	COG1309	transcriptional regulator
B3913_RS18780	COG2816	NAD+ diphosphatase activity
B3913_RS18785	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B3913_RS18870	COG2814	Major facilitator Superfamily
B3913_RS18875	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
B3913_RS18895	COG1999	signal sequence binding
B3913_RS18900	COG0109	protoheme IX farnesyltransferase activity
B3913_RS18940	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B3913_RS18960	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
B3913_RS18965	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B3913_RS18975	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
B3913_RS18980	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
B3913_RS18990	COG0070	glutamate synthase
B3913_RS18990	COG0069	glutamate synthase activity
B3913_RS18990	COG0067	glutamate synthase
B3913_RS19000	COG3047	cAMP biosynthetic process
B3913_RS19010	COG1127	ABC transporter
B3913_RS19015	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
B3913_RS19020	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
B3913_RS19025	COG2853	Lipoprotein
B3913_RS19035	COG1131	(ABC) transporter
B3913_RS19040	COG0842	Transport permease protein
B3913_RS19050	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
B3913_RS19055	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
B3913_RS19060	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
B3913_RS19065	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
B3913_RS19070	COG0131	Imidazoleglycerol-phosphate dehydratase
B3913_RS19075	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
B3913_RS19080	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
B3913_RS19085	COG0107	imidazoleglycerol-phosphate synthase activity
B3913_RS19090	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
B3913_RS19095	COG0140	phosphoribosyl-ATP diphosphatase activity
B3913_RS19100	COG0537	adenosine 5'-monophosphoramidase activity
B3913_RS19105	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B3913_RS19110	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B3913_RS19125	COG3181	Tripartite tricarboxylate transporter family receptor
B3913_RS19160	COG3702	type iv secretory pathway
B3913_RS19165	COG3451	type IV secretory pathway VirB4
B3913_RS19180	COG3736	Type IV secretory pathway, component VirB8
B3913_RS19185	COG3504	Conjugal transfer protein
B3913_RS19190	COG2948	multi-organism process
B3913_RS19195	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
B3913_RS19205	COG0697	spore germination
B3913_RS19225	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
B3913_RS19230	COG0747	negative chemotaxis
B3913_RS19235	COG0601	transmembrane transport
B3913_RS19240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B3913_RS19245	COG0444	Belongs to the ABC transporter superfamily
B3913_RS19255	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
B3913_RS19265	COG0494	nUDIX hydrolase
B3913_RS19305	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
B3913_RS19310	COG0237	dephospho-CoA kinase activity
B3913_RS19315	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
B3913_RS19330	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
B3913_RS19335	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
B3913_RS19345	COG0477	Major facilitator Superfamily
B3913_RS19350	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
B3913_RS19365	COG1126	abc transporter atp-binding protein
B3913_RS19370	COG0765	amino acid transport
B3913_RS19375	COG4597	amino acid ABC transporter
B3913_RS19380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B3913_RS19385	COG2884	Cell division ATP-binding protein ftsE
B3913_RS19390	COG2177	Part of the ABC transporter FtsEX involved in
B3913_RS19395	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
B3913_RS19405	COG1194	a g-specific adenine glycosylase
B3913_RS19415	COG2226	methyltransferase
B3913_RS19425	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B3913_RS19430	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B3913_RS19445	COG1024	Enoyl-CoA hydratase
B3913_RS19465	COG1024	Enoyl-CoA hydratase
B3913_RS19470	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B3913_RS19475	COG3181	Tripartite tricarboxylate transporter family receptor
B3913_RS19485	COG0753	catalase activity
B3913_RS19490	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B3913_RS19495	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
B3913_RS19505	COG2175	clavaminate synthase activity
B3913_RS19510	COG1473	amidohydrolase
B3913_RS19515	COG4608	Belongs to the ABC transporter superfamily
B3913_RS19520	COG0444	Belongs to the ABC transporter superfamily
B3913_RS19535	COG0747	negative chemotaxis
B3913_RS19540	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
B3913_RS19575	COG0436	Aminotransferase
B3913_RS19580	COG1278	Cold shock