locus-tag	class	description
WG72_RS00005	COG0445	tRNA wobble uridine modification
WG72_RS00010	COG0357	Ribosomal RNA small subunit methyltransferase G
WG72_RS00015	COG1192	Involved in chromosome partitioning
WG72_RS00025	COG1475	DNA binding
WG72_RS00030	COG0252	asparaginase activity
WG72_RS00055	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
WG72_RS00065	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
WG72_RS00075	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
WG72_RS00080	COG0081	regulation of translation
WG72_RS00085	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
WG72_RS00090	COG0222	ribosome binding
WG72_RS00095	COG0085	RNA polymerase activity
WG72_RS00100	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
WG72_RS00140	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WG72_RS00165	COG1024	Enoyl-CoA hydratase
WG72_RS00185	COG0752	glycyl-tRNA synthetase alpha subunit
WG72_RS00190	COG0751	glycine-tRNA ligase activity
WG72_RS00195	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
WG72_RS00200	COG0204	Acyl-transferase
WG72_RS00215	COG0242	peptide deformylase activity
WG72_RS00250	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
WG72_RS00255	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
WG72_RS00260	COG2813	Specifically methylates the guanine in position
WG72_RS00260	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
WG72_RS00275	COG2223	nitrite transmembrane transporter activity
WG72_RS00285	COG1794	racemase activity, acting on amino acids and derivatives
WG72_RS00290	COG1126	abc transporter atp-binding protein
WG72_RS00295	COG0765	amino acid transport
WG72_RS00300	COG0765	amino acid transport
WG72_RS00305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WG72_RS00370	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
WG72_RS00400	COG0326	Molecular chaperone. Has ATPase activity
WG72_RS00405	COG0625	glutathione transferase activity
WG72_RS00420	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
WG72_RS00425	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
WG72_RS00455	COG0438	transferase activity, transferring glycosyl groups
WG72_RS00460	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
WG72_RS00465	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
WG72_RS00495	COG0859	PFAM glycosyl transferase family 9
WG72_RS00510	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
WG72_RS00520	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
WG72_RS00525	COG1127	ABC transporter
WG72_RS00545	COG1686	Belongs to the peptidase S11 family
WG72_RS00555	COG2921	Belongs to the UPF0250 family
WG72_RS00560	COG0321	lipoyl(octanoyl) transferase activity
WG72_RS00565	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
WG72_RS00600	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
WG72_RS00610	COG0018	arginyl-trna synthetase
WG72_RS00630	COG0395	ABC-type sugar transport system, permease component
WG72_RS00635	COG1175	transmembrane transport
WG72_RS00640	COG1653	transport
WG72_RS00645	COG3842	ATPase activity
WG72_RS00650	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
WG72_RS00660	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
WG72_RS00680	COG1609	Transcriptional regulator
WG72_RS00690	COG0154	amidase activity
WG72_RS00695	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
WG72_RS00705	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
WG72_RS00715	COG0583	DNA-binding transcription factor activity
WG72_RS00730	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WG72_RS00735	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
WG72_RS00750	COG1802	Transcriptional regulator
WG72_RS00765	COG1024	Enoyl-CoA hydratase
WG72_RS00775	COG3181	Tripartite tricarboxylate transporter family receptor
WG72_RS00790	COG1984	allophanate hydrolase subunit 2
WG72_RS00795	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
WG72_RS00805	COG0583	DNA-binding transcription factor activity
WG72_RS00810	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
WG72_RS00820	COG5002	protein histidine kinase activity
WG72_RS00830	COG5002	protein histidine kinase activity
WG72_RS00835	COG0745	RESPONSE REGULATOR receiver
WG72_RS00840	COG2226	methyltransferase
WG72_RS00855	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
WG72_RS00875	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
WG72_RS00885	COG0513	Belongs to the DEAD box helicase family
WG72_RS00890	COG1280	lysine exporter protein (LysE YggA)
WG72_RS00895	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
WG72_RS00930	COG1054	Belongs to the UPF0176 family
WG72_RS00935	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WG72_RS00935	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WG72_RS00945	COG0489	protein tyrosine kinase activity
WG72_RS00960	COG0717	Belongs to the dCTP deaminase family
WG72_RS00990	COG2081	HI0933 family
WG72_RS01000	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
WG72_RS01010	COG0404	The glycine cleavage system catalyzes the degradation of glycine
WG72_RS01015	COG0509	glycine decarboxylation via glycine cleavage system
WG72_RS01020	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
WG72_RS01020	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
WG72_RS01065	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
WG72_RS01080	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
WG72_RS01090	COG1414	Transcriptional regulator
WG72_RS01095	COG1028	Short-chain dehydrogenase reductase Sdr
WG72_RS01100	COG2031	fatty acid transporter
WG72_RS01105	COG1250	3-hydroxyacyl-CoA dehydrogenase
WG72_RS01115	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
WG72_RS01120	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
WG72_RS01130	COG4257	antibiotic catabolic process
WG72_RS01155	COG1012	belongs to the aldehyde dehydrogenase family
WG72_RS01160	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
WG72_RS01165	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WG72_RS01190	COG1028	Short-chain dehydrogenase reductase Sdr
WG72_RS01200	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WG72_RS01215	COG2188	Transcriptional regulator
WG72_RS01220	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
WG72_RS01245	COG0617	tRNA 3'-terminal CCA addition
WG72_RS01260	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
WG72_RS01265	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
WG72_RS01270	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
WG72_RS01275	COG0586	Pfam SNARE associated Golgi protein
WG72_RS01280	COG0860	N-Acetylmuramoyl-L-alanine amidase
WG72_RS01285	COG0802	atpase or kinase
WG72_RS01290	COG0114	fumarate hydratase activity
WG72_RS01300	COG3181	Tripartite tricarboxylate transporter family receptor
WG72_RS01310	COG0405	Gamma-glutamyltransferase
WG72_RS01315	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WG72_RS01325	COG1960	acyl-CoA dehydrogenase activity
WG72_RS01350	COG1294	oxidase, subunit
WG72_RS01360	COG4988	ABC transporter
WG72_RS01365	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
WG72_RS01370	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
WG72_RS01385	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WG72_RS01415	COG2969	positive regulation of protein catabolic process
WG72_RS01420	COG0625	glutathione transferase activity
WG72_RS01425	COG2857	Cytochrome c1
WG72_RS01430	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
WG72_RS01435	COG0723	plastoquinol--plastocyanin reductase activity
WG72_RS01440	COG1970	mechanosensitive ion channel activity
WG72_RS01445	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
WG72_RS01465	COG2808	Putative FMN-binding domain
WG72_RS01470	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
WG72_RS01475	COG0747	negative chemotaxis
WG72_RS01480	COG0657	acetylesterase activity
WG72_RS01490	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
WG72_RS01495	COG2207	Transcriptional regulator
WG72_RS01500	COG0129	dihydroxy-acid dehydratase activity
WG72_RS01505	COG2814	Major facilitator Superfamily
WG72_RS01510	COG0583	DNA-binding transcription factor activity
WG72_RS01520	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
WG72_RS01590	COG1024	Enoyl-CoA hydratase
WG72_RS01595	COG1960	acyl-CoA dehydrogenase activity
WG72_RS01620	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
WG72_RS01625	COG0352	thiamine-phosphate diphosphorylase activity
WG72_RS01640	COG1678	Uncharacterized ACR, COG1678
WG72_RS01645	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
WG72_RS01650	COG0540	Belongs to the ATCase OTCase family
WG72_RS01665	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
WG72_RS01675	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
WG72_RS01710	COG1234	tRNA 3'-trailer cleavage
WG72_RS01730	COG3064	Membrane
WG72_RS01760	COG1683	Conserved Protein
WG72_RS01765	COG1120	ATPase activity
WG72_RS01770	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WG72_RS01775	COG4558	Periplasmic binding protein
WG72_RS01780	COG3720	iron ion transport
WG72_RS01790	COG3712	iron ion homeostasis
WG72_RS01795	COG1595	DNA-templated transcription, initiation
WG72_RS01830	COG1802	Transcriptional regulator
WG72_RS01840	COG3069	C4-dicarboxylate transmembrane transporter activity
WG72_RS01850	COG1012	belongs to the aldehyde dehydrogenase family
WG72_RS01885	COG2860	membrane
WG72_RS01890	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
WG72_RS01895	COG0708	Exodeoxyribonuclease III
WG72_RS01900	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
WG72_RS01905	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
WG72_RS01910	COG0154	amidase activity
WG72_RS01915	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
WG72_RS01920	COG1077	Cell shape determining protein MreB Mrl
WG72_RS01925	COG1792	Involved in formation and maintenance of cell shape
WG72_RS01935	COG0768	penicillin binding
WG72_RS01940	COG0772	Belongs to the SEDS family
WG72_RS01945	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
WG72_RS01950	COG0471	metal ion transport
WG72_RS01955	COG1309	transcriptional regulator
WG72_RS01965	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
WG72_RS01980	COG2823	Periplasmic or secreted lipoprotein
WG72_RS01985	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
WG72_RS02000	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
WG72_RS02020	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WG72_RS02030	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WG72_RS02050	COG0492	ferredoxin-NADP+ reductase activity
WG72_RS02060	COG3181	Tripartite tricarboxylate transporter family receptor
WG72_RS02065	COG1250	3-hydroxyacyl-CoA dehydrogenase
WG72_RS02065	COG1024	Enoyl-CoA hydratase
WG72_RS02070	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WG72_RS02075	COG0028	Belongs to the TPP enzyme family
WG72_RS02100	COG3181	Tripartite tricarboxylate transporter family receptor
WG72_RS02110	COG0697	spore germination
WG72_RS02140	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
WG72_RS02145	COG0463	Glycosyl transferase, family 2
WG72_RS02165	COG0786	glutamate:sodium symporter activity
WG72_RS02175	COG2031	fatty acid transporter
WG72_RS02190	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
WG72_RS02195	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WG72_RS02205	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
WG72_RS02220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WG72_RS02230	COG1285	pathogenesis
WG72_RS02235	COG1253	flavin adenine dinucleotide binding
WG72_RS02240	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WG72_RS02245	COG1024	Enoyl-CoA hydratase
WG72_RS02250	COG3181	Tripartite tricarboxylate transporter family receptor
WG72_RS02255	COG0583	DNA-binding transcription factor activity
WG72_RS02260	COG1960	acyl-CoA dehydrogenase activity
WG72_RS02270	COG0183	Belongs to the thiolase family
WG72_RS02290	COG0583	DNA-binding transcription factor activity
WG72_RS02295	COG1278	Cold shock
WG72_RS02305	COG1802	Transcriptional regulator
WG72_RS02310	COG1012	belongs to the aldehyde dehydrogenase family
WG72_RS02315	COG2031	fatty acid transporter
WG72_RS02320	COG1017	nitric oxide dioxygenase activity
WG72_RS02320	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WG72_RS02325	COG0251	oxidation-reduction process
WG72_RS02345	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WG72_RS02355	COG0583	DNA-binding transcription factor activity
WG72_RS02360	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WG72_RS02370	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
WG72_RS02375	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
WG72_RS02380	COG0546	phosphoglycolate phosphatase activity
WG72_RS02390	COG1530	ribonuclease E activity
WG72_RS02405	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
WG72_RS02410	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
WG72_RS02415	COG0159	tryptophan synthase activity
WG72_RS02420	COG0133	tryptophan synthase activity
WG72_RS02430	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
WG72_RS02435	COG3228	Belongs to the MtfA family
WG72_RS02445	COG0251	oxidation-reduction process
WG72_RS02450	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
WG72_RS02455	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
WG72_RS02470	COG2878	Part of a membrane complex involved in electron transport
WG72_RS02475	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
WG72_RS02510	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
WG72_RS02530	COG1268	BioY protein
WG72_RS02535	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
WG72_RS02540	COG1122	ATPase activity
WG72_RS02545	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
WG72_RS02560	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
WG72_RS02565	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
WG72_RS02575	COG1196	nuclear chromosome segregation
WG72_RS02580	COG0477	Major facilitator Superfamily
WG72_RS02585	COG1573	uracil-dna glycosylase
WG72_RS02590	COG1214	PFAM Peptidase M22, glycoprotease
WG72_RS02615	COG0450	alkyl hydroperoxide reductase
WG72_RS02620	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WG72_RS02630	COG2223	nitrite transmembrane transporter activity
WG72_RS02640	COG2186	Transcriptional regulator
WG72_RS02660	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
WG72_RS02670	COG0583	DNA-binding transcription factor activity
WG72_RS02680	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
WG72_RS02685	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
WG72_RS02690	COG0137	argininosuccinate synthase activity
WG72_RS02695	COG3158	transport of potassium into the cell
WG72_RS02700	COG0642	Histidine kinase
WG72_RS02730	COG0776	regulation of translation
WG72_RS02735	COG3128	pkhd-type hydroxylase
WG72_RS02745	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
WG72_RS02750	COG0557	exoribonuclease II activity
WG72_RS02775	COG0679	Auxin Efflux Carrier
WG72_RS02780	COG2391	methyltransferase activity
WG72_RS02785	COG0069	glutamate synthase activity
WG72_RS02795	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WG72_RS02805	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
WG72_RS02810	COG1262	PFAM Formylglycine-generating sulfatase enzyme
WG72_RS02845	COG3706	GGDEF domain
WG72_RS02865	COG1053	succinate dehydrogenase
WG72_RS02870	COG0583	DNA-binding transcription factor activity
WG72_RS02880	COG1053	succinate dehydrogenase
WG72_RS02900	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
WG72_RS02905	COG0459	protein refolding
WG72_RS02910	COG3468	outer membrane autotransporter barrel domain protein
WG72_RS02925	COG1252	NADH dehydrogenase
WG72_RS02930	COG0284	orotidine-5'-phosphate decarboxylase activity
WG72_RS02935	COG1058	Belongs to the CinA family
WG72_RS02935	COG1546	Belongs to the CinA family
WG72_RS02940	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
WG72_RS02950	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
WG72_RS02955	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
WG72_RS02990	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
WG72_RS02995	COG3639	organic phosphonate transmembrane transporter activity
WG72_RS03000	COG3639	organic phosphonate transmembrane transporter activity
WG72_RS03020	COG0742	ribosomal rna small subunit methyltransferase
WG72_RS03025	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
WG72_RS03030	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
WG72_RS03035	COG3135	benzoate transporter
WG72_RS03050	COG0640	Transcriptional regulator
WG72_RS03080	COG4172	Belongs to the ABC transporter superfamily
WG72_RS03085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WG72_RS03090	COG0601	transmembrane transport
WG72_RS03100	COG0281	malic enzyme
WG72_RS03100	COG0280	phosphate acetyltransferase
WG72_RS03160	COG0583	DNA-binding transcription factor activity
WG72_RS03170	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
WG72_RS03175	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
WG72_RS03180	COG0167	dihydroorotate dehydrogenase activity
WG72_RS03200	COG1414	Transcriptional regulator
WG72_RS03205	COG1058	Belongs to the CinA family
WG72_RS03205	COG1546	Belongs to the CinA family
WG72_RS03225	COG0513	Belongs to the DEAD box helicase family
WG72_RS03255	COG0429	hydrolase of the alpha beta-hydrolase fold
WG72_RS03260	COG4783	chaperone-mediated protein folding
WG72_RS03275	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WG72_RS03300	COG0006	proline dipeptidase activity
WG72_RS03310	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WG72_RS03330	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
WG72_RS03335	COG0632	four-way junction helicase activity
WG72_RS03350	COG2255	four-way junction helicase activity
WG72_RS03355	COG0514	ATP-dependent DNA helicase (RecQ)
WG72_RS03370	COG0288	reversible hydration of carbon dioxide
WG72_RS03375	COG0154	amidase activity
WG72_RS03385	COG4211	Belongs to the binding-protein-dependent transport system permease family
WG72_RS03415	COG1464	Belongs to the NlpA lipoprotein family
WG72_RS03560	COG1196	nuclear chromosome segregation
WG72_RS03630	COG2135	peptidase activity
WG72_RS03645	COG0494	nUDIX hydrolase
WG72_RS03650	COG0442	prolyl-tRNA aminoacylation
WG72_RS03655	COG0824	Thioesterase
WG72_RS03660	COG0811	peptide transport
WG72_RS03665	COG0848	biopolymer transport protein
WG72_RS03675	COG0823	Involved in the tonB-independent uptake of proteins
WG72_RS03690	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WG72_RS03695	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
WG72_RS03730	COG0700	Nucleoside recognition
WG72_RS03735	COG0469	pyruvate kinase activity
WG72_RS03740	COG1929	Belongs to the glycerate kinase type-1 family
WG72_RS03745	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
WG72_RS03750	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
WG72_RS03755	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
WG72_RS03765	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
WG72_RS03775	COG2154	pterin-4-alpha-carbinolamine dehydratase
WG72_RS03800	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
WG72_RS03805	COG0154	amidase activity
WG72_RS03815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WG72_RS03820	COG0601	transmembrane transport
WG72_RS03825	COG0747	negative chemotaxis
WG72_RS03845	COG0019	diaminopimelate decarboxylase activity
WG72_RS03860	COG2353	YceI-like domain
WG72_RS03865	COG4774	siderophore transport
WG72_RS03870	COG3712	iron ion homeostasis
WG72_RS03910	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
WG72_RS03915	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
WG72_RS03920	COG0211	Belongs to the bacterial ribosomal protein bL27 family
WG72_RS03925	COG0261	This protein binds to 23S rRNA in the presence of protein L20
WG72_RS03935	COG0142	geranyltranstransferase activity
WG72_RS03945	COG0583	DNA-binding transcription factor activity
WG72_RS03955	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
WG72_RS03960	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WG72_RS03975	COG2994	toxin metabolic process
WG72_RS03985	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
WG72_RS03990	COG2274	protein secretion by the type I secretion system
WG72_RS03995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WG72_RS04000	COG1538	Outer membrane efflux protein
WG72_RS04015	COG0765	amino acid transport
WG72_RS04020	COG0765	amino acid transport
WG72_RS04025	COG1126	abc transporter atp-binding protein
WG72_RS04045	COG1028	Short-chain dehydrogenase reductase Sdr
WG72_RS04055	COG1802	Transcriptional regulator
WG72_RS04065	COG1802	Transcriptional regulator
WG72_RS04075	COG0318	PFAM AMP-dependent synthetase and ligase
WG72_RS04085	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WG72_RS04105	COG0028	Belongs to the TPP enzyme family
WG72_RS04125	COG0308	aminopeptidase N
WG72_RS04130	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
WG72_RS04140	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
WG72_RS04145	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
WG72_RS04150	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
WG72_RS04155	COG0560	Phosphoserine phosphatase
WG72_RS04160	COG0583	DNA-binding transcription factor activity
WG72_RS04165	COG3181	Tripartite tricarboxylate transporter family receptor
WG72_RS04170	COG0028	Belongs to the TPP enzyme family
WG72_RS04185	COG4774	siderophore transport
WG72_RS04190	COG4774	siderophore transport
WG72_RS04200	COG1007	ATP synthesis coupled electron transport
WG72_RS04215	COG0713	ATP synthesis coupled electron transport
WG72_RS04225	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WG72_RS04230	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
WG72_RS04235	COG1034	ATP synthesis coupled electron transport
WG72_RS04245	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
WG72_RS04250	COG0649	NAD binding
WG72_RS04255	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WG72_RS04260	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WG72_RS04265	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WG72_RS04270	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WG72_RS04300	COG0671	phosphoesterase, PA-phosphatase related
WG72_RS04310	COG1597	lipid kinase activity
WG72_RS04315	COG0583	DNA-binding transcription factor activity
WG72_RS04320	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
WG72_RS04330	COG1733	regulation of RNA biosynthetic process
WG72_RS04335	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WG72_RS04340	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WG72_RS04355	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
WG72_RS04375	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WG72_RS04395	COG3608	succinylglutamate desuccinylase aspartoacylase
WG72_RS04400	COG0626	cystathionine gamma-synthase activity
WG72_RS04405	COG0583	DNA-binding transcription factor activity
WG72_RS04440	COG3799	methylaspartate ammonia-lyase activity
WG72_RS04450	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
WG72_RS04460	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
WG72_RS04465	COG0149	triose-phosphate isomerase activity
WG72_RS04485	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
WG72_RS04500	COG1185	polyribonucleotide nucleotidyltransferase activity
WG72_RS04505	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
WG72_RS04520	COG1183	phosphatidylcholine synthase activity
WG72_RS04525	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
WG72_RS04530	COG0440	acetolactate synthase activity
WG72_RS04535	COG0028	Belongs to the TPP enzyme family
WG72_RS04550	COG5265	(ABC) transporter
WG72_RS04555	COG0500	methyltransferase
WG72_RS04575	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
WG72_RS04595	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
WG72_RS04605	COG0511	ligase activity, forming carbon-carbon bonds
WG72_RS04630	COG2188	Transcriptional regulator
WG72_RS04635	COG0439	Biotin carboxylase
WG72_RS04640	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
WG72_RS04685	COG5265	(ABC) transporter
WG72_RS04695	COG0667	Aldo Keto reductase
WG72_RS04710	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
WG72_RS04750	COG0583	DNA-binding transcription factor activity
WG72_RS04775	COG2814	Major facilitator Superfamily
WG72_RS04785	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
WG72_RS04800	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
WG72_RS04810	COG0287	Prephenate dehydrogenase
WG72_RS04815	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
WG72_RS04820	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
WG72_RS04840	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
WG72_RS04845	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
WG72_RS04850	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WG72_RS04855	COG1596	polysaccharide export
WG72_RS04855	COG1555	photosystem II stabilization
WG72_RS04870	COG2951	lytic endotransglycosylase activity
WG72_RS04875	COG0123	including yeast histone deacetylase and acetoin utilization protein
WG72_RS04890	COG1960	acyl-CoA dehydrogenase activity
WG72_RS04895	COG0450	alkyl hydroperoxide reductase
WG72_RS04910	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
WG72_RS04915	COG4208	sulfate ABC transporter
WG72_RS04920	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
WG72_RS04950	COG0335	large ribosomal subunit rRNA binding
WG72_RS04965	COG0667	Aldo Keto reductase
WG72_RS04975	COG2814	Major facilitator Superfamily
WG72_RS04980	COG3161	chorismate lyase activity
WG72_RS04985	COG1187	pseudouridine synthase activity
WG72_RS04995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WG72_RS05015	COG1999	signal sequence binding
WG72_RS05020	COG0339	signal peptide processing
WG72_RS05025	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
WG72_RS05030	COG4566	intracellular signal transduction
WG72_RS05040	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
WG72_RS05045	COG0508	dehydrogenase complex catalyzes the overall conversion of
WG72_RS05050	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WG72_RS05055	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
WG72_RS05070	COG1385	rRNA (uridine-N3-)-methyltransferase activity
WG72_RS05075	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
WG72_RS05080	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
WG72_RS05085	COG0126	phosphoglycerate kinase activity
WG72_RS05090	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
WG72_RS05095	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
WG72_RS05110	COG0625	glutathione transferase activity
WG72_RS05145	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
WG72_RS05155	COG0521	Mo-molybdopterin cofactor biosynthetic process
WG72_RS05165	COG0739	heme binding
WG72_RS05175	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
WG72_RS05210	COG0745	RESPONSE REGULATOR receiver
WG72_RS05225	COG0840	transmembrane signaling receptor activity
WG72_RS05235	COG2201	protein-glutamate methylesterase activity
WG72_RS05240	COG0745	RESPONSE REGULATOR receiver
WG72_RS05245	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
WG72_RS05270	COG0667	Aldo Keto reductase
WG72_RS05280	COG4535	Mg2 and Co2 transporter CorC
WG72_RS05285	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
WG72_RS05290	COG1702	phosphate starvation-inducible protein PhoH
WG72_RS05295	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
WG72_RS05310	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WG72_RS05315	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WG72_RS05320	COG1862	Preprotein translocase
WG72_RS05325	COG0343	queuine tRNA-ribosyltransferase activity
WG72_RS05330	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
WG72_RS05335	COG2027	D-alanyl-D-alanine carboxypeptidase
WG72_RS05340	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
WG72_RS05350	COG3468	outer membrane autotransporter barrel domain protein
WG72_RS05355	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
WG72_RS05355	COG1648	precorrin-2 dehydrogenase activity
WG72_RS05380	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
WG72_RS05385	COG0741	lytic transglycosylase activity
WG72_RS05390	COG0436	Aminotransferase
WG72_RS05400	COG0280	phosphate acetyltransferase
WG72_RS05400	COG0281	malic enzyme
WG72_RS05410	COG2732	(Barnase) inhibitor
WG72_RS05425	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
WG72_RS05450	COG0248	Ppx GppA phosphatase
WG72_RS05460	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
WG72_RS05470	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
WG72_RS05475	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
WG72_RS05480	COG1534	Rna-binding protein
WG72_RS05510	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
WG72_RS05525	COG1295	ribonuclease BN
WG72_RS05535	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
WG72_RS05540	COG0745	RESPONSE REGULATOR receiver
WG72_RS05545	COG2205	protein histidine kinase activity
WG72_RS05580	COG1022	Amp-dependent synthetase and ligase
WG72_RS05595	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
WG72_RS05600	COG1028	Short-chain dehydrogenase reductase Sdr
WG72_RS05610	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
WG72_RS05625	COG1136	(ABC) transporter
WG72_RS05630	COG0084	hydrolase, TatD family'
WG72_RS05660	COG0658	competence protein
WG72_RS05660	COG2333	competence protein COMEC
WG72_RS05670	COG0613	PHP domain protein
WG72_RS05685	COG3539	Fimbrial protein
WG72_RS05690	COG0281	malic enzyme
WG72_RS05690	COG0280	phosphate acetyltransferase
WG72_RS05700	COG1522	sequence-specific DNA binding
WG72_RS05710	COG0567	Dehydrogenase, E1 component
WG72_RS05715	COG0508	dehydrogenase complex catalyzes the overall conversion of
WG72_RS05720	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WG72_RS05725	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
WG72_RS05730	COG1028	Short-chain dehydrogenase reductase Sdr
WG72_RS05735	COG0583	DNA-binding transcription factor activity
WG72_RS05745	COG3181	Tripartite tricarboxylate transporter family receptor
WG72_RS05770	COG0180	Tryptophanyl-tRNA synthetase
WG72_RS05775	COG2183	response to ionizing radiation
WG72_RS05780	COG1199	ATP-dependent helicase activity
WG72_RS05790	COG0564	pseudouridine synthase activity
WG72_RS05800	COG3243	poly(R)-hydroxyalkanoic acid synthase
WG72_RS05805	COG1028	Short-chain dehydrogenase reductase Sdr
WG72_RS05810	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
WG72_RS05825	COG0672	)-iron permease
WG72_RS05865	COG0583	DNA-binding transcription factor activity
WG72_RS05875	COG2814	Major facilitator Superfamily
WG72_RS05890	COG1619	proteins homologs of microcin C7 resistance protein MccF
WG72_RS05905	COG2084	Dehydrogenase
WG72_RS05910	COG3181	Tripartite tricarboxylate transporter family receptor
WG72_RS05935	COG2988	succinylglutamate desuccinylase activity
WG72_RS05965	COG0765	amino acid transport
WG72_RS05970	COG0765	amino acid transport
WG72_RS05975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WG72_RS06010	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WG72_RS06015	COG1595	DNA-templated transcription, initiation
WG72_RS06025	COG3530	Putative quorum-sensing-regulated virulence factor
WG72_RS06030	COG0494	nUDIX hydrolase
WG72_RS06045	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
WG72_RS06050	COG0542	response to heat
WG72_RS06065	COG3468	outer membrane autotransporter barrel domain protein
WG72_RS06070	COG3468	outer membrane autotransporter barrel domain protein
WG72_RS06080	COG5441	Belongs to the UPF0261 family
WG72_RS06085	COG5564	TIM-barrel signal transduction protein
WG72_RS06100	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
WG72_RS06115	COG1477	protein flavinylation
WG72_RS06135	COG1131	(ABC) transporter
WG72_RS06140	COG0842	Transport permease protein
WG72_RS06150	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
WG72_RS06155	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
WG72_RS06155	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
WG72_RS06160	COG1562	ergosterol biosynthetic process
WG72_RS06165	COG1562	ergosterol biosynthetic process
WG72_RS06170	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
WG72_RS06175	COG1028	Short-chain dehydrogenase reductase Sdr
WG72_RS06195	COG2304	oxidoreductase activity
WG72_RS06215	COG0534	Mate efflux family protein
WG72_RS06225	COG0254	rRNA binding
WG72_RS06230	COG3483	tryptophan 2,3-dioxygenase activity
WG72_RS06235	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
WG72_RS06240	COG2003	Belongs to the UPF0758 family
WG72_RS06245	COG1047	Peptidyl-prolyl cis-trans
WG72_RS06250	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
WG72_RS06255	COG0625	glutathione transferase activity
WG72_RS06275	COG0523	cobalamin synthesis protein
WG72_RS06285	COG0583	DNA-binding transcription factor activity
WG72_RS06295	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
WG72_RS06300	COG1187	pseudouridine synthase activity
WG72_RS06305	COG0779	Required for maturation of 30S ribosomal subunits
WG72_RS06310	COG0195	Participates in both transcription termination and antitermination
WG72_RS06310	COG2251	uridine kinase activity
WG72_RS06315	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
WG72_RS06320	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
WG72_RS06325	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
WG72_RS06345	COG1611	Belongs to the LOG family
WG72_RS06360	COG0412	Dienelactone hydrolase
WG72_RS06365	COG1283	sodium-dependent phosphate transmembrane transporter activity
WG72_RS06370	COG1760	l-serine dehydratase
WG72_RS06375	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
WG72_RS06380	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
WG72_RS06390	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
WG72_RS06415	COG2311	Membrane
WG72_RS06425	COG0697	spore germination
WG72_RS06440	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
WG72_RS06455	COG0559	Belongs to the binding-protein-dependent transport system permease family
WG72_RS06470	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
WG72_RS06480	COG1653	transport
WG72_RS06485	COG1175	transmembrane transport
WG72_RS06490	COG0395	ABC-type sugar transport system, permease component
WG72_RS06495	COG3842	ATPase activity
WG72_RS06520	COG2363	Small membrane protein
WG72_RS06535	COG1464	Belongs to the NlpA lipoprotein family
WG72_RS06545	COG0688	phosphatidylethanolamine metabolic process
WG72_RS06570	COG0625	glutathione transferase activity
WG72_RS06575	COG0386	Belongs to the glutathione peroxidase family
WG72_RS06595	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WG72_RS06625	COG2259	Doxx family
WG72_RS06640	COG0667	Aldo Keto reductase
WG72_RS06670	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
WG72_RS06690	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
WG72_RS06700	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
WG72_RS06740	COG0392	lysyltransferase activity
WG72_RS06755	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WG72_RS06760	COG3568	Endonuclease Exonuclease Phosphatase
WG72_RS06770	COG1695	Transcriptional regulator
WG72_RS06790	COG0583	DNA-binding transcription factor activity
WG72_RS06805	COG1802	Transcriptional regulator
WG72_RS06815	COG3181	Tripartite tricarboxylate transporter family receptor
WG72_RS06825	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WG72_RS06840	COG0066	3-isopropylmalate dehydratase activity
WG72_RS06850	COG3181	Tripartite tricarboxylate transporter family receptor
WG72_RS06855	COG4948	Mandelate Racemase Muconate Lactonizing
WG72_RS06870	COG1126	abc transporter atp-binding protein
WG72_RS06875	COG0765	amino acid transport
WG72_RS06880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WG72_RS06900	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
WG72_RS06925	COG1815	bacterial-type flagellum-dependent cell motility
WG72_RS06930	COG1558	bacterial-type flagellum-dependent cell motility
WG72_RS06940	COG1749	Flagellar hook protein flgE
WG72_RS06955	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
WG72_RS06960	COG1706	bacterial-type flagellum-dependent cell motility
WG72_RS06970	COG1256	bacterial-type flagellum assembly
WG72_RS06980	COG0840	transmembrane signaling receptor activity
WG72_RS06985	COG0840	transmembrane signaling receptor activity
WG72_RS06990	COG0840	transmembrane signaling receptor activity
WG72_RS07010	COG1338	Plays a role in the flagellum-specific transport system
WG72_RS07030	COG1580	Controls the rotational direction of flagella during chemotaxis
WG72_RS07055	COG1157	protein secretion by the type III secretion system
WG72_RS07060	COG1317	bacterial-type flagellum organization
WG72_RS07065	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
WG72_RS07075	COG1677	Flagellar hook-basal body complex protein FliE
WG72_RS07085	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
WG72_RS07120	COG0285	dihydrofolate synthase activity
WG72_RS07150	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
WG72_RS07155	COG0024	Methionine aminopeptidase
WG72_RS07160	COG0052	Belongs to the universal ribosomal protein uS2 family
WG72_RS07165	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
WG72_RS07170	COG0528	UMP kinase activity
WG72_RS07175	COG0233	cytoplasmic translational termination
WG72_RS07180	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
WG72_RS07190	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
WG72_RS07195	COG0750	zinc metalloprotease
WG72_RS07200	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
WG72_RS07205	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
WG72_RS07210	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
WG72_RS07215	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
WG72_RS07225	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
WG72_RS07230	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
WG72_RS07235	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
WG72_RS07240	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
WG72_RS07250	COG0518	GMP synthase (glutamine-hydrolyzing) activity
WG72_RS07250	COG0519	Catalyzes the synthesis of GMP from XMP
WG72_RS07265	COG0330	HflC and HflK could
WG72_RS07270	COG3706	GGDEF domain
WG72_RS07275	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
WG72_RS07285	COG2867	negative regulation of translational initiation
WG72_RS07295	COG1960	acyl-CoA dehydrogenase activity
WG72_RS07300	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
WG72_RS07330	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
WG72_RS07335	COG0505	Belongs to the CarA family
WG72_RS07340	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
WG72_RS07350	COG0406	alpha-ribazole phosphatase activity
WG72_RS07360	COG3842	ATPase activity
WG72_RS07380	COG5001	Diguanylate cyclase
WG72_RS07385	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
WG72_RS07395	COG1763	Mo-molybdopterin cofactor biosynthetic process
WG72_RS07400	COG0303	'Molybdopterin
WG72_RS07405	COG0746	molybdenum cofactor guanylyltransferase activity
WG72_RS07410	COG0489	protein tyrosine kinase activity
WG72_RS07440	COG3383	formate dehydrogenase (NAD+) activity
WG72_RS07440	COG0243	molybdopterin cofactor binding
WG72_RS07445	COG0437	4 iron, 4 sulfur cluster binding
WG72_RS07475	COG1122	ATPase activity
WG72_RS07485	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
WG72_RS07490	COG0066	3-isopropylmalate dehydratase activity
WG72_RS07495	COG0473	3-isopropylmalate dehydrogenase activity
WG72_RS07500	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
WG72_RS07510	COG0101	tRNA pseudouridine synthase activity
WG72_RS07515	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
WG72_RS07530	COG0135	phosphoribosylanthranilate isomerase activity
WG72_RS07545	COG3022	response to hydroperoxide
WG72_RS07555	COG1289	transmembrane transporter activity
WG72_RS07560	COG3023	N-Acetylmuramoyl-L-alanine amidase
WG72_RS07570	COG0424	maF-like protein
WG72_RS07575	COG1399	metal-binding, possibly nucleic acid-binding protein
WG72_RS07580	COG0333	Belongs to the bacterial ribosomal protein bL32 family
WG72_RS07585	COG0416	fatty acid biosynthetic process
WG72_RS07590	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
WG72_RS07605	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
WG72_RS07610	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
WG72_RS07635	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WG72_RS07640	COG0481	GTPase activity
WG72_RS07645	COG0681	Belongs to the peptidase S26 family
WG72_RS07650	COG0571	ribonuclease III activity
WG72_RS07655	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
WG72_RS07660	COG1381	Involved in DNA repair and RecF pathway recombination
WG72_RS07670	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
WG72_RS07680	COG3181	Tripartite tricarboxylate transporter family receptor
WG72_RS07685	COG0670	Belongs to the BI1 family
WG72_RS07700	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
WG72_RS07710	COG0583	DNA-binding transcription factor activity
WG72_RS07725	COG0583	DNA-binding transcription factor activity
WG72_RS07740	COG0791	NLP P60 protein
WG72_RS07745	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
WG72_RS07750	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
WG72_RS07755	COG3193	protein, possibly involved in utilization of glycolate and propanediol
WG72_RS07765	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
WG72_RS07770	COG0697	spore germination
WG72_RS07775	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
WG72_RS07790	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
WG72_RS07820	COG1446	asparaginase
WG72_RS07825	COG4172	Belongs to the ABC transporter superfamily
WG72_RS07830	COG0747	negative chemotaxis
WG72_RS07840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WG72_RS07865	COG0504	CTP synthase activity
WG72_RS07870	COG2877	3-deoxy-8-phosphooctulonate synthase activity
WG72_RS07880	COG0148	phosphopyruvate hydratase activity
WG72_RS07885	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
WG72_RS07915	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
WG72_RS07925	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
WG72_RS07950	COG1981	membrane
WG72_RS07980	COG0039	L-malate dehydrogenase activity
WG72_RS07985	COG2188	Transcriptional regulator
WG72_RS07990	COG2009	succinate dehydrogenase
WG72_RS07995	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
WG72_RS08000	COG1053	succinate dehydrogenase
WG72_RS08005	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
WG72_RS08010	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
WG72_RS08015	COG0372	Belongs to the citrate synthase family
WG72_RS08035	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
WG72_RS08035	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
WG72_RS08045	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
WG72_RS08050	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
WG72_RS08065	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
WG72_RS08070	COG3842	ATPase activity
WG72_RS08075	COG1176	ABC-type spermidine putrescine transport system, permease component I
WG72_RS08080	COG1177	transmembrane transport
WG72_RS08105	COG1960	acyl-CoA dehydrogenase activity
WG72_RS08110	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
WG72_RS08115	COG0704	Plays a role in the regulation of phosphate uptake
WG72_RS08125	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
WG72_RS08130	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
WG72_RS08130	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
WG72_RS08135	COG1643	Atp-dependent helicase
WG72_RS08150	COG0438	transferase activity, transferring glycosyl groups
WG72_RS08155	COG0726	polysaccharide deacetylase
WG72_RS08160	COG0463	Glycosyl transferase, family 2
WG72_RS08165	COG0438	transferase activity, transferring glycosyl groups
WG72_RS08170	COG2194	sulfuric ester hydrolase activity
WG72_RS08195	COG0859	PFAM glycosyl transferase family 9
WG72_RS08200	COG1132	(ABC) transporter
WG72_RS08215	COG0077	Prephenate dehydratase
WG72_RS08220	COG1530	ribonuclease E activity
WG72_RS08260	COG3468	outer membrane autotransporter barrel domain protein
WG72_RS08265	COG0424	maF-like protein
WG72_RS08270	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
WG72_RS08275	COG0799	negative regulation of ribosome biogenesis
WG72_RS08280	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
WG72_RS08285	COG0408	coproporphyrinogen oxidase activity
WG72_RS08290	COG0151	Belongs to the GarS family
WG72_RS08295	COG0217	transcriptional regulatory protein
WG72_RS08300	COG0433	COG0433 Predicted ATPase
WG72_RS08305	COG1115	amino acid carrier protein
WG72_RS08310	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
WG72_RS08320	COG1012	belongs to the aldehyde dehydrogenase family
WG72_RS08345	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
WG72_RS08360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WG72_RS08370	COG0747	negative chemotaxis
WG72_RS08380	COG0473	3-isopropylmalate dehydrogenase activity
WG72_RS08385	COG2814	Major facilitator Superfamily
WG72_RS08390	COG1566	PFAM secretion protein HlyD family protein
WG72_RS08400	COG1846	Transcriptional regulator
WG72_RS08410	COG0697	spore germination
WG72_RS08420	COG0501	Belongs to the peptidase M48B family
WG72_RS08440	COG0583	DNA-binding transcription factor activity
WG72_RS08445	COG3842	ATPase activity
WG72_RS08450	COG1178	ABC-type Fe3 transport system permease component
WG72_RS08455	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
WG72_RS08460	COG1840	ABC-type Fe3 transport system, periplasmic component
WG72_RS08465	COG0492	ferredoxin-NADP+ reductase activity
WG72_RS08485	COG2233	PERMEase
WG72_RS08490	COG0840	transmembrane signaling receptor activity
WG72_RS08495	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
WG72_RS08525	COG4789	Type iii secretion
WG72_RS08590	COG4669	(LipO)protein
WG72_RS08625	COG4790	Type iii secretion
WG72_RS08630	COG4794	Type iii secretion
WG72_RS08635	COG4791	protein targeting
WG72_RS08640	COG4792	protein secretion
WG72_RS08655	COG1595	DNA-templated transcription, initiation
WG72_RS08680	COG2770	Histidine kinase
WG72_RS08680	COG2208	phosphoserine phosphatase activity
WG72_RS08690	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
WG72_RS08695	COG2172	sigma factor antagonist activity
WG72_RS08700	COG1366	Belongs to the anti-sigma-factor antagonist family
WG72_RS08705	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WG72_RS08735	COG2358	TRAP transporter, solute receptor (TAXI family
WG72_RS08740	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
WG72_RS08770	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
WG72_RS08780	COG2252	PERMEase
WG72_RS08785	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
WG72_RS08795	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
WG72_RS08800	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
WG72_RS08830	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
WG72_RS08835	COG0789	Transcriptional regulator
WG72_RS08845	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
WG72_RS08845	COG0678	peroxiredoxin activity
WG72_RS08855	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
WG72_RS08860	COG0584	glycerophosphoryl diester phosphodiesterase
WG72_RS08865	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
WG72_RS08875	COG4181	ATPase activity
WG72_RS08890	COG2823	Periplasmic or secreted lipoprotein
WG72_RS08900	COG3237	CsbD-like
WG72_RS08905	COG1181	Belongs to the D-alanine--D-alanine ligase family
WG72_RS08905	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
WG72_RS08910	COG0189	ligase activity
WG72_RS08910	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
WG72_RS08930	COG2833	Protein of unknown function (DUF455)
WG72_RS08935	COG2951	lytic endotransglycosylase activity
WG72_RS08955	COG1522	sequence-specific DNA binding
WG72_RS08965	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
WG72_RS08970	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
WG72_RS08975	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
WG72_RS08980	COG0196	riboflavin kinase activity
WG72_RS08985	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
WG72_RS09005	COG0210	DNA helicase
WG72_RS09010	COG4771	TonB-dependent receptor
WG72_RS09015	COG0488	(ABC) transporter
WG72_RS09020	COG2890	protein-(glutamine-N5) methyltransferase activity
WG72_RS09025	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
WG72_RS09030	COG2171	N-acyltransferase activity
WG72_RS09065	COG1278	Cold shock
WG72_RS09085	COG0544	peptidyl-prolyl cis-trans isomerase activity
WG72_RS09090	COG0740	serine-type endopeptidase activity
WG72_RS09095	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
WG72_RS09100	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
WG72_RS09105	COG0583	DNA-binding transcription factor activity
WG72_RS09110	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WG72_RS09125	COG1024	Enoyl-CoA hydratase
WG72_RS09135	COG0183	Belongs to the thiolase family
WG72_RS09140	COG1028	Short-chain dehydrogenase reductase Sdr
WG72_RS09145	COG1960	acyl-CoA dehydrogenase activity
WG72_RS09160	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
WG72_RS09190	COG3468	outer membrane autotransporter barrel domain protein
WG72_RS09195	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
WG72_RS09205	COG0556	nucleotide-excision repair
WG72_RS09210	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
WG72_RS09220	COG1104	cysteine desulfurase activity
WG72_RS09225	COG0822	iron-sulfur transferase activity
WG72_RS09230	COG0316	Belongs to the HesB IscA family
WG72_RS09235	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
WG72_RS09240	COG0443	Heat shock 70 kDa protein
WG72_RS09245	COG0633	Ferredoxin
WG72_RS09265	COG1024	Enoyl-CoA hydratase
WG72_RS09280	COG3395	kinase activity
WG72_RS09285	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
WG72_RS09300	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
WG72_RS09310	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WG72_RS09335	COG0747	negative chemotaxis
WG72_RS09340	COG0601	transmembrane transport
WG72_RS09345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WG72_RS09350	COG4172	Belongs to the ABC transporter superfamily
WG72_RS09355	COG0154	amidase activity
WG72_RS09400	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
WG72_RS09405	COG0425	Belongs to the sulfur carrier protein TusA family
WG72_RS09415	COG0228	four-way junction DNA binding
WG72_RS09420	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
WG72_RS09425	COG0336	Belongs to the RNA methyltransferase TrmD family
WG72_RS09430	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
WG72_RS09450	COG0642	Histidine kinase
WG72_RS09465	COG0525	valine-tRNA ligase activity
WG72_RS09470	COG0105	UTP biosynthetic process
WG72_RS09475	COG0820	rRNA (adenine-C2-)-methyltransferase activity
WG72_RS09485	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
WG72_RS09490	COG0124	histidyl-tRNA synthetase
WG72_RS09495	COG2976	Protein conserved in bacteria
WG72_RS09500	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
WG72_RS09505	COG1160	GTP binding
WG72_RS09510	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
WG72_RS09515	COG1923	regulation of RNA biosynthetic process
WG72_RS09520	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
WG72_RS09525	COG0330	HflC and HflK could
WG72_RS09530	COG0330	HflC and HflK could
WG72_RS09535	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
WG72_RS09540	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
WG72_RS09545	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
WG72_RS09550	COG0828	Belongs to the bacterial ribosomal protein bS21 family
WG72_RS09560	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
WG72_RS09595	COG0628	permease
WG72_RS09600	COG0842	Transport permease protein
WG72_RS09605	COG1131	(ABC) transporter
WG72_RS09675	COG0156	8-amino-7-oxononanoate synthase activity
WG72_RS09685	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
WG72_RS09685	COG4106	trans-aconitate 2-methyltransferase activity
WG72_RS09690	COG1380	Effector of murein hydrolase LrgA
WG72_RS09705	COG3284	Transcriptional regulator
WG72_RS09710	COG1012	belongs to the aldehyde dehydrogenase family
WG72_RS09725	COG2733	membrane
WG72_RS09730	COG0583	DNA-binding transcription factor activity
WG72_RS09735	COG0384	phenazine biosynthesis protein PhzF
WG72_RS09740	COG5507	3-demethylubiquinone-9 3-methyltransferase
WG72_RS09745	COG2169	Transcriptional regulator
WG72_RS09775	COG0659	secondary active sulfate transmembrane transporter activity
WG72_RS09800	COG1132	(ABC) transporter
WG72_RS09845	COG2207	Transcriptional regulator
WG72_RS09980	COG2346	COG2346, Truncated hemoglobins
WG72_RS10025	COG0183	Belongs to the thiolase family
WG72_RS10040	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WG72_RS10045	COG0633	Ferredoxin
WG72_RS10055	COG1024	Enoyl-CoA hydratase
WG72_RS10065	COG4638	Rieske (2fe-2S)
WG72_RS10075	COG0559	Belongs to the binding-protein-dependent transport system permease family
WG72_RS10095	COG2224	Isocitrate lyase
WG72_RS10100	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
WG72_RS10100	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
WG72_RS10115	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
WG72_RS10120	COG0322	excinuclease ABC activity
WG72_RS10125	COG1472	Belongs to the glycosyl hydrolase 3 family
WG72_RS10130	COG0736	holo-[acyl-carrier-protein] synthase activity
WG72_RS10135	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
WG72_RS10145	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WG72_RS10150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WG72_RS10175	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
WG72_RS10190	COG2032	superoxide dismutase activity
WG72_RS10205	COG1024	Enoyl-CoA hydratase
WG72_RS10215	COG1802	Transcriptional regulator
WG72_RS10225	COG0183	Belongs to the thiolase family
WG72_RS10230	COG1942	4-Oxalocrotonate Tautomerase
WG72_RS10240	COG4176	ABC-type proline glycine betaine transport system permease component
WG72_RS10255	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
WG72_RS10260	COG2814	Major facilitator Superfamily
WG72_RS10265	COG0227	Belongs to the bacterial ribosomal protein bL28 family
WG72_RS10270	COG0267	Belongs to the bacterial ribosomal protein bL33 family
WG72_RS10300	COG2814	Major facilitator Superfamily
WG72_RS10305	COG0495	leucyl-tRNA aminoacylation
WG72_RS10320	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
WG72_RS10330	COG0154	amidase activity
WG72_RS10335	COG1250	3-hydroxyacyl-CoA dehydrogenase
WG72_RS10390	COG0427	acetyl-CoA hydrolase
WG72_RS10395	COG0583	DNA-binding transcription factor activity
WG72_RS10415	COG0730	response to heat
WG72_RS10420	COG0697	spore germination
WG72_RS10455	COG2885	chlorophyll binding
WG72_RS10480	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
WG72_RS10485	COG3384	dioxygenase
WG72_RS10500	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
WG72_RS10505	COG3474	cytochrome
WG72_RS10515	COG1595	DNA-templated transcription, initiation
WG72_RS10530	COG2204	response regulator
WG72_RS10570	COG4964	Belongs to the GSP D family
WG72_RS10620	COG1846	Transcriptional regulator
WG72_RS10625	COG4172	Belongs to the ABC transporter superfamily
WG72_RS10630	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WG72_RS10635	COG0601	transmembrane transport
WG72_RS10640	COG0747	negative chemotaxis
WG72_RS10650	COG0598	Magnesium transport protein CorA
WG72_RS10655	COG0210	DNA helicase
WG72_RS10670	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
WG72_RS10675	COG1012	belongs to the aldehyde dehydrogenase family
WG72_RS10680	COG0483	inositol monophosphate 1-phosphatase activity
WG72_RS10685	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
WG72_RS10695	COG1045	serine acetyltransferase
WG72_RS10700	COG0166	Belongs to the GPI family
WG72_RS10715	COG2197	response regulator
WG72_RS10720	COG1846	Transcriptional regulator
WG72_RS10740	COG0726	polysaccharide deacetylase
WG72_RS10740	COG1649	PFAM Uncharacterised BCR, COG1649
WG72_RS10745	COG1215	transferase activity, transferring glycosyl groups
WG72_RS10755	COG1902	pentaerythritol trinitrate reductase activity
WG72_RS10780	COG0251	oxidation-reduction process
WG72_RS10790	COG1832	CoA-binding protein
WG72_RS10795	COG1414	Transcriptional regulator
WG72_RS10800	COG1902	pentaerythritol trinitrate reductase activity
WG72_RS10800	COG0446	pyridine nucleotide-disulphide oxidoreductase
WG72_RS10810	COG3842	ATPase activity
WG72_RS10840	COG0583	DNA-binding transcription factor activity
WG72_RS10850	COG1028	Short-chain dehydrogenase reductase Sdr
WG72_RS10855	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
WG72_RS10860	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
WG72_RS10875	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
WG72_RS10875	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
WG72_RS10880	COG1250	3-hydroxyacyl-CoA dehydrogenase
WG72_RS10905	COG0527	aspartate kinase activity
WG72_RS10910	COG0037	tRNA processing
WG72_RS10920	COG0825	malonyl-CoA metabolic process
WG72_RS10930	COG0215	cysteine-tRNA ligase activity
WG72_RS10945	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
WG72_RS10950	COG1968	undecaprenyl-diphosphatase activity
WG72_RS10955	COG1253	flavin adenine dinucleotide binding
WG72_RS10960	COG0483	inositol monophosphate 1-phosphatase activity
WG72_RS10980	COG0668	transmembrane transport
WG72_RS11005	COG0583	DNA-binding transcription factor activity
WG72_RS11030	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
WG72_RS11045	COG2831	hemolysin activation secretion protein
WG72_RS11050	COG3539	Fimbrial protein
WG72_RS11055	COG3188	usher protein
WG72_RS11060	COG3121	Chaperone
WG72_RS11070	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
WG72_RS11070	COG3210	domain, Protein
WG72_RS11070	COG3064	Membrane
WG72_RS11075	COG2197	response regulator
WG72_RS11080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WG72_RS11080	COG2205	protein histidine kinase activity
WG72_RS11090	COG4336	lyase activity
WG72_RS11115	COG2010	Cytochrome c
WG72_RS11120	COG3189	MarR family transcriptional regulator
WG72_RS11135	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
WG72_RS11145	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
WG72_RS11145	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
WG72_RS11155	COG0028	Belongs to the TPP enzyme family
WG72_RS11165	COG1012	belongs to the aldehyde dehydrogenase family
WG72_RS11170	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
WG72_RS11175	COG0010	Belongs to the arginase family
WG72_RS11180	COG1126	abc transporter atp-binding protein
WG72_RS11190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WG72_RS11205	COG0084	hydrolase, TatD family'
WG72_RS11210	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
WG72_RS11215	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
WG72_RS11220	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
WG72_RS11235	COG0587	DNA-directed DNA polymerase activity
WG72_RS11245	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WG72_RS11250	COG1959	2 iron, 2 sulfur cluster binding
WG72_RS11255	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WG72_RS11255	COG1017	nitric oxide dioxygenase activity
WG72_RS11290	COG0488	(ABC) transporter
WG72_RS11295	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
WG72_RS11310	COG1024	Enoyl-CoA hydratase
WG72_RS11315	COG1619	proteins homologs of microcin C7 resistance protein MccF
WG72_RS11320	COG0590	tRNA wobble adenosine to inosine editing
WG72_RS11345	COG2212	antiporter activity
WG72_RS11350	COG1863	multisubunit Na H antiporter MnhE subunit
WG72_RS11355	COG0651	ATP synthesis coupled electron transport
WG72_RS11360	COG1006	Multisubunit Na H antiporter MnhC subunit
WG72_RS11365	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
WG72_RS11365	COG2111	Na H antiporter
WG72_RS11370	COG3181	Tripartite tricarboxylate transporter family receptor
WG72_RS11385	COG0583	DNA-binding transcription factor activity
WG72_RS11390	COG1028	Short-chain dehydrogenase reductase Sdr
WG72_RS11420	COG0431	NADPH-dependent FMN reductase
WG72_RS11465	COG1028	Short-chain dehydrogenase reductase Sdr
WG72_RS11470	COG0179	Fumarylacetoacetate (FAA) hydrolase
WG72_RS11500	COG0625	glutathione transferase activity
WG72_RS11505	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
WG72_RS11510	COG2944	sequence-specific DNA binding
WG72_RS11520	COG2197	response regulator
WG72_RS11545	COG3119	arylsulfatase activity
WG72_RS11580	COG0714	Associated with various cellular activities
WG72_RS11600	COG1028	Short-chain dehydrogenase reductase Sdr
WG72_RS11605	COG0861	Integral membrane protein TerC family
WG72_RS11650	COG0300	oxidoreductase activity
WG72_RS11675	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
WG72_RS11690	COG0438	transferase activity, transferring glycosyl groups
WG72_RS11710	COG0463	Glycosyl transferase, family 2
WG72_RS11725	COG0783	Belongs to the Dps family
WG72_RS11740	COG0583	DNA-binding transcription factor activity
WG72_RS11745	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
WG72_RS11760	COG0656	L-ascorbic acid biosynthetic process
WG72_RS11770	COG0583	DNA-binding transcription factor activity
WG72_RS11780	COG1840	ABC-type Fe3 transport system, periplasmic component
WG72_RS11785	COG1178	ABC-type Fe3 transport system permease component
WG72_RS11790	COG3842	ATPase activity
WG72_RS11800	COG1741	Belongs to the pirin family
WG72_RS11805	COG1741	Belongs to the pirin family
WG72_RS11810	COG0583	DNA-binding transcription factor activity
WG72_RS11815	COG2204	response regulator
WG72_RS11825	COG0174	glutamine synthetase
WG72_RS11830	COG0635	Involved in the biosynthesis of porphyrin-containing compound
WG72_RS11840	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
WG72_RS11845	COG2199	diguanylate cyclase activity
WG72_RS11845	COG2200	EAL domain
WG72_RS11850	COG0840	transmembrane signaling receptor activity
WG72_RS11865	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
WG72_RS11870	COG1561	YicC-like family, N-terminal region
WG72_RS11890	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
WG72_RS11895	COG0791	NLP P60 protein
WG72_RS11900	COG1028	Short-chain dehydrogenase reductase Sdr
WG72_RS11905	COG2863	cytochrome
WG72_RS11910	COG3258	Cytochrome c
WG72_RS11915	COG0194	GDP metabolic process
WG72_RS11920	COG1758	RNA polymerase activity
WG72_RS11925	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
WG72_RS11930	COG1126	abc transporter atp-binding protein
WG72_RS11935	COG0765	amino acid transport
WG72_RS11940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WG72_RS11960	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WG72_RS11965	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
WG72_RS11970	COG3539	Fimbrial protein
WG72_RS11975	COG2850	peptidyl-arginine hydroxylation
WG72_RS11980	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
WG72_RS11985	COG3360	Dodecin
WG72_RS12030	COG0009	L-threonylcarbamoyladenylate synthase
WG72_RS12035	COG2321	neutral zinc metallopeptidase
WG72_RS12055	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
WG72_RS12060	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
WG72_RS12065	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
WG72_RS12080	COG1074	ATP-dependent DNA helicase activity
WG72_RS12090	COG2814	Major facilitator Superfamily
WG72_RS12100	COG1686	Belongs to the peptidase S11 family
WG72_RS12115	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
WG72_RS12120	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
WG72_RS12125	COG4974	Belongs to the 'phage' integrase family
WG72_RS12130	COG0583	DNA-binding transcription factor activity
WG72_RS12135	COG0028	Belongs to the TPP enzyme family
WG72_RS12150	COG0028	Belongs to the TPP enzyme family
WG72_RS12155	COG1126	abc transporter atp-binding protein
WG72_RS12160	COG0765	amino acid transport
WG72_RS12175	COG1414	Transcriptional regulator
WG72_RS12180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WG72_RS12185	COG0009	L-threonylcarbamoyladenylate synthase
WG72_RS12190	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
WG72_RS12195	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
WG72_RS12200	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
WG72_RS12210	COG2944	sequence-specific DNA binding
WG72_RS12220	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
WG72_RS12275	COG1126	abc transporter atp-binding protein
WG72_RS12280	COG0765	amino acid transport
WG72_RS12285	COG0765	amino acid transport
WG72_RS12290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WG72_RS12300	COG2423	ornithine cyclodeaminase activity
WG72_RS12305	COG1764	response to oxidative stress
WG72_RS12315	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
WG72_RS12320	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
WG72_RS12330	COG0189	ligase activity
WG72_RS12335	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
WG72_RS12340	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
WG72_RS12345	COG2197	response regulator
WG72_RS12355	COG0635	Involved in the biosynthesis of porphyrin-containing compound
WG72_RS12375	COG1289	transmembrane transporter activity
WG72_RS12385	COG3022	response to hydroperoxide
WG72_RS12395	COG1028	Short-chain dehydrogenase reductase Sdr
WG72_RS12410	COG3486	L-lysine 6-monooxygenase (NADPH) activity
WG72_RS12440	COG2814	Major facilitator Superfamily
WG72_RS12460	COG3706	GGDEF domain
WG72_RS12485	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
WG72_RS12490	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
WG72_RS12495	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
WG72_RS12500	COG1674	ftsk spoiiie
WG72_RS12505	COG0492	ferredoxin-NADP+ reductase activity
WG72_RS12510	COG1193	negative regulation of DNA recombination
WG72_RS12530	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
WG72_RS12545	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
WG72_RS12550	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
WG72_RS12555	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
WG72_RS12565	COG0745	RESPONSE REGULATOR receiver
WG72_RS12610	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
WG72_RS12630	COG0612	Peptidase, M16
WG72_RS12640	COG0443	Heat shock 70 kDa protein
WG72_RS12650	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
WG72_RS12660	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
WG72_RS12665	COG1420	regulation of RNA biosynthetic process
WG72_RS12670	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
WG72_RS12675	COG0497	DNA recombination
WG72_RS12680	COG0735	belongs to the Fur family
WG72_RS12685	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
WG72_RS12690	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
WG72_RS12695	COG0812	UDP-N-acetylmuramate dehydrogenase activity
WG72_RS12730	COG0404	The glycine cleavage system catalyzes the degradation of glycine
WG72_RS12730	COG0446	pyridine nucleotide-disulphide oxidoreductase
WG72_RS12735	COG4311	Sarcosine oxidase, delta subunit
WG72_RS12740	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WG72_RS12750	COG0583	DNA-binding transcription factor activity
WG72_RS12760	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
WG72_RS12790	COG4964	Belongs to the GSP D family
WG72_RS12850	COG0181	hydroxymethylbilane synthase activity
WG72_RS12855	COG0861	Integral membrane protein TerC family
WG72_RS12860	COG0861	Integral membrane protein TerC family
WG72_RS12865	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
WG72_RS12870	COG0045	succinate-CoA ligase (ADP-forming) activity
WG72_RS12880	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
WG72_RS12890	COG2137	regulation of response to DNA damage stimulus
WG72_RS12895	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
WG72_RS12915	COG1250	3-hydroxyacyl-CoA dehydrogenase
WG72_RS12915	COG1024	Enoyl-CoA hydratase
WG72_RS12920	COG3842	ATPase activity
WG72_RS12935	COG1028	Short-chain dehydrogenase reductase Sdr
WG72_RS12955	COG0583	DNA-binding transcription factor activity
WG72_RS12960	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WG72_RS12970	COG2974	May be involved in recombination
WG72_RS12975	COG0540	Belongs to the ATCase OTCase family
WG72_RS13050	COG0776	regulation of translation
WG72_RS13055	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WG72_RS13055	COG0072	phenylalanine-tRNA ligase activity
WG72_RS13060	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
WG72_RS13065	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
WG72_RS13070	COG0291	Belongs to the bacterial ribosomal protein bL35 family
WG72_RS13085	COG0756	dUTP diphosphatase activity
WG72_RS13095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WG72_RS13110	COG0500	methyltransferase
WG72_RS13125	COG0586	Pfam SNARE associated Golgi protein
WG72_RS13155	COG1609	Transcriptional regulator
WG72_RS13160	COG4172	Belongs to the ABC transporter superfamily
WG72_RS13165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WG72_RS13170	COG0601	transmembrane transport
WG72_RS13175	COG0747	negative chemotaxis
WG72_RS13190	COG1280	lysine exporter protein (LysE YggA)
WG72_RS13205	COG2814	Major facilitator Superfamily
WG72_RS13235	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
WG72_RS13255	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
WG72_RS13295	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WG72_RS13300	COG1116	anion transmembrane transporter activity
WG72_RS13310	COG1228	amidohydrolase
WG72_RS13325	COG0477	Major facilitator Superfamily
WG72_RS13335	COG3550	peptidyl-serine autophosphorylation
WG72_RS13350	COG0519	Catalyzes the synthesis of GMP from XMP
WG72_RS13350	COG0518	GMP synthase (glutamine-hydrolyzing) activity
WG72_RS13395	COG0420	3'-5' exonuclease activity
WG72_RS13400	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WG72_RS13430	COG0395	ABC-type sugar transport system, permease component
WG72_RS13440	COG3842	ATPase activity
WG72_RS13470	COG3181	Tripartite tricarboxylate transporter family receptor
WG72_RS13505	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WG72_RS13530	COG0602	queuosine metabolic process
WG72_RS13535	COG0720	synthase
WG72_RS13540	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
WG72_RS13545	COG0235	Class ii aldolase
WG72_RS13570	COG3210	domain, Protein
WG72_RS13570	COG3064	Membrane
WG72_RS13570	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
WG72_RS13575	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
WG72_RS13575	COG0047	phosphoribosylformylglycinamidine synthase activity
WG72_RS13580	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
WG72_RS13585	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
WG72_RS13585	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
WG72_RS13590	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
WG72_RS13610	COG3539	Fimbrial protein
WG72_RS13620	COG2050	protein possibly involved in aromatic compounds catabolism
WG72_RS13625	COG1024	Enoyl-CoA hydratase
WG72_RS13630	COG1012	belongs to the aldehyde dehydrogenase family
WG72_RS13640	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WG72_RS13645	COG2151	metal-sulfur cluster biosynthetic enzyme
WG72_RS13650	COG3396	Phenylacetate-CoA oxygenase
WG72_RS13655	COG3460	Phenylacetate-CoA oxygenase
WG72_RS13660	COG3396	Phenylacetate-CoA oxygenase
WG72_RS13665	COG3327	negative regulation of DNA-templated transcription, initiation
WG72_RS13675	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
WG72_RS13680	COG0501	Belongs to the peptidase M48B family
WG72_RS13685	COG1162	GTPase activity
WG72_RS13690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WG72_RS13695	COG0601	transmembrane transport
WG72_RS13700	COG0747	negative chemotaxis
WG72_RS13745	COG0668	transmembrane transport
WG72_RS13750	COG0165	Argininosuccinate lyase
WG72_RS13770	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
WG72_RS13775	COG0303	'Molybdopterin
WG72_RS13780	COG0521	Mo-molybdopterin cofactor biosynthetic process
WG72_RS13795	COG0315	cyclic pyranopterin monophosphate synthase activity
WG72_RS13805	COG0412	Dienelactone hydrolase
WG72_RS13815	COG0678	peroxiredoxin activity
WG72_RS13825	COG0697	spore germination
WG72_RS13830	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
WG72_RS13855	COG0789	Transcriptional regulator
WG72_RS13875	COG1028	Short-chain dehydrogenase reductase Sdr
WG72_RS13885	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
WG72_RS13890	COG1845	cytochrome c oxidase, subunit III
WG72_RS13895	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
WG72_RS13905	COG0477	Major facilitator Superfamily
WG72_RS13935	COG3468	outer membrane autotransporter barrel domain protein
WG72_RS13945	COG1309	transcriptional regulator
WG72_RS13950	COG2271	Major facilitator Superfamily
WG72_RS13985	COG0506	proline dehydrogenase activity
WG72_RS13985	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
WG72_RS13985	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
WG72_RS13995	COG3008	intermembrane lipid transfer
WG72_RS13995	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
WG72_RS14000	COG2995	paraquat-inducible protein a
WG72_RS14005	COG0542	response to heat
WG72_RS14010	COG4953	penicillin-binding protein 1C
WG72_RS14020	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
WG72_RS14025	COG1278	Cold shock
WG72_RS14035	COG0183	Belongs to the thiolase family
WG72_RS14040	COG0038	chloride channel
WG72_RS14045	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
WG72_RS14050	COG1570	exodeoxyribonuclease VII activity
WG72_RS14060	COG0811	peptide transport
WG72_RS14065	COG0848	biopolymer transport protein
WG72_RS14070	COG1663	tetraacyldisaccharide 4'-kinase activity
WG72_RS14075	COG2835	tetraacyldisaccharide 4'-kinase activity
WG72_RS14080	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
WG72_RS14085	COG0563	adenylate kinase activity
WG72_RS14095	COG0728	peptidoglycan biosynthetic process
WG72_RS14105	COG0268	Binds directly to 16S ribosomal RNA
WG72_RS14135	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
WG72_RS14160	COG0436	Aminotransferase
WG72_RS14165	COG3737	Protein of unknown function (DUF498/DUF598)
WG72_RS14170	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
WG72_RS14180	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
WG72_RS14190	COG0305	Participates in initiation and elongation during chromosome replication
WG72_RS14200	COG0359	binds to the 23S rRNA
WG72_RS14205	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
WG72_RS14210	COG2965	DNA replication, synthesis of RNA primer
WG72_RS14215	COG0360	Binds together with S18 to 16S ribosomal RNA
WG72_RS14220	COG1469	GTP cyclohydrolase I activity
WG72_RS14225	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
WG72_RS14230	COG0142	geranyltranstransferase activity
WG72_RS14235	COG1722	exodeoxyribonuclease VII activity
WG72_RS14245	COG3181	Tripartite tricarboxylate transporter family receptor
WG72_RS14265	COG2239	Acts as a magnesium transporter
WG72_RS14275	COG2855	membrane
WG72_RS14285	COG1473	amidohydrolase
WG72_RS14290	COG0318	PFAM AMP-dependent synthetase and ligase
WG72_RS14315	COG1501	Belongs to the glycosyl hydrolase 31 family
WG72_RS14320	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
WG72_RS14325	COG2011	ABC-type metal ion transport system permease component
WG72_RS14345	COG1454	alcohol dehydrogenase
WG72_RS14375	COG2186	Transcriptional regulator
WG72_RS14380	COG3181	Tripartite tricarboxylate transporter family receptor
WG72_RS14400	COG1175	transmembrane transport
WG72_RS14405	COG0395	ABC-type sugar transport system, permease component
WG72_RS14410	COG3842	ATPase activity
WG72_RS14415	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WG72_RS14425	COG1653	transport
WG72_RS14445	COG2818	Glycosylase
WG72_RS14450	COG2982	Protein involved in outer membrane biogenesis
WG72_RS14460	COG1309	transcriptional regulator
WG72_RS14465	COG1028	Short-chain dehydrogenase reductase Sdr
WG72_RS14525	COG0583	DNA-binding transcription factor activity
WG72_RS14530	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
WG72_RS14535	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WG72_RS14550	COG1028	Short-chain dehydrogenase reductase Sdr
WG72_RS14555	COG0477	Major facilitator Superfamily
WG72_RS14565	COG0583	DNA-binding transcription factor activity
WG72_RS14570	COG1448	Aminotransferase
WG72_RS14575	COG1418	mRNA catabolic process
WG72_RS14600	COG1063	alcohol dehydrogenase
WG72_RS14620	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WG72_RS14630	COG0318	PFAM AMP-dependent synthetase and ligase
WG72_RS14640	COG1522	sequence-specific DNA binding
WG72_RS14645	COG3181	Tripartite tricarboxylate transporter family receptor
WG72_RS14650	COG0307	riboflavin synthase, alpha
WG72_RS14655	COG0154	amidase activity
WG72_RS14675	COG2807	transmembrane transport
WG72_RS14680	COG0590	tRNA wobble adenosine to inosine editing
WG72_RS14690	COG0583	DNA-binding transcription factor activity
WG72_RS14705	COG1902	pentaerythritol trinitrate reductase activity
WG72_RS14725	COG0559	Belongs to the binding-protein-dependent transport system permease family
WG72_RS14730	COG0251	oxidation-reduction process
WG72_RS14735	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
WG72_RS14745	COG1414	Transcriptional regulator
WG72_RS14750	COG1028	Short-chain dehydrogenase reductase Sdr
WG72_RS14765	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WG72_RS14780	COG1024	Enoyl-CoA hydratase
WG72_RS14785	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WG72_RS14790	COG0154	amidase activity
WG72_RS14830	COG3909	cytochrome
WG72_RS14835	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
WG72_RS14840	COG0625	glutathione transferase activity
WG72_RS14845	COG0730	response to heat
WG72_RS14850	COG0482	sulfurtransferase activity
WG72_RS14855	COG0583	DNA-binding transcription factor activity
WG72_RS14875	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
WG72_RS14900	COG2819	hydrolase of the alpha beta superfamily
WG72_RS14905	COG0247	lactate metabolic process
WG72_RS14910	COG0277	FAD linked oxidase domain protein
WG72_RS14915	COG0277	FAD linked oxidase domain protein
WG72_RS14920	COG0277	FAD linked oxidase domain protein
WG72_RS14925	COG3064	Membrane
WG72_RS14925	COG3210	domain, Protein
WG72_RS14925	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
WG72_RS14925	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
WG72_RS14925	COG3210	domain, Protein
WG72_RS14925	COG3064	Membrane
WG72_RS14930	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
WG72_RS14935	COG0312	modulator of DNA gyrase
WG72_RS14970	COG1666	GTP binding
WG72_RS15015	COG3220	belongs to the UPF0276 family
WG72_RS15035	COG0640	Transcriptional regulator
WG72_RS15040	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
WG72_RS15045	COG1845	cytochrome c oxidase, subunit III
WG72_RS15050	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
WG72_RS15060	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
WG72_RS15095	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WG72_RS15100	COG0583	DNA-binding transcription factor activity
WG72_RS15130	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
WG72_RS15130	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
WG72_RS15145	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
WG72_RS15150	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
WG72_RS15160	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
WG72_RS15175	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
WG72_RS15180	COG0316	Belongs to the HesB IscA family
WG72_RS15190	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
WG72_RS15195	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
WG72_RS15200	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
WG72_RS15205	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
WG72_RS15210	COG0312	modulator of DNA gyrase
WG72_RS15215	COG3028	Belongs to the UPF0307 family
WG72_RS15230	COG1116	anion transmembrane transporter activity
WG72_RS15235	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WG72_RS15240	COG1335	isochorismatase
WG72_RS15245	COG0346	lactoylglutathione lyase activity
WG72_RS15250	COG0513	Belongs to the DEAD box helicase family
WG72_RS15255	COG3069	C4-dicarboxylate transmembrane transporter activity
WG72_RS15260	COG1802	Transcriptional regulator
WG72_RS15275	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WG72_RS15275	COG1042	CoA-binding domain protein
WG72_RS15275	COG0045	succinate-CoA ligase (ADP-forming) activity
WG72_RS15280	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
WG72_RS15295	COG1522	sequence-specific DNA binding
WG72_RS15330	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
WG72_RS15335	COG1696	Membrane protein involved in D-alanine export
WG72_RS15360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WG72_RS15370	COG2264	protein methyltransferase activity
WG72_RS15375	COG0439	Biotin carboxylase
WG72_RS15380	COG0511	ligase activity, forming carbon-carbon bonds
WG72_RS15385	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
WG72_RS15390	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
WG72_RS15395	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
WG72_RS15400	COG3150	esterase
WG72_RS15405	COG0557	exoribonuclease II activity
WG72_RS15415	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
WG72_RS15435	COG1522	sequence-specific DNA binding
WG72_RS15440	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WG72_RS15445	COG1028	Short-chain dehydrogenase reductase Sdr
WG72_RS15465	COG0653	protein targeting
WG72_RS15470	COG0739	heme binding
WG72_RS15480	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
WG72_RS15485	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
WG72_RS15495	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
WG72_RS15500	COG1181	Belongs to the D-alanine--D-alanine ligase family
WG72_RS15505	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
WG72_RS15510	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
WG72_RS15520	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
WG72_RS15525	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
WG72_RS15530	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
WG72_RS15540	COG3116	cell division
WG72_RS15545	COG0275	rRNA processing
WG72_RS15550	COG2001	Belongs to the MraZ family
WG72_RS15560	COG0488	(ABC) transporter
WG72_RS15565	COG0418	dihydroorotase activity
WG72_RS15570	COG1473	amidohydrolase
WG72_RS15620	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
WG72_RS15625	COG4654	Cytochrome c, class I
WG72_RS15630	COG0129	dihydroxy-acid dehydratase activity
WG72_RS15635	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
WG72_RS15685	COG2084	Dehydrogenase
WG72_RS15690	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
WG72_RS15705	COG2096	Adenosyltransferase
WG72_RS15715	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
WG72_RS15720	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
WG72_RS15730	COG0523	cobalamin synthesis protein
WG72_RS15735	COG0735	belongs to the Fur family
WG72_RS15755	COG0803	Belongs to the bacterial solute-binding protein 9 family
WG72_RS15765	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
WG72_RS15775	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
WG72_RS15785	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
WG72_RS15790	COG1560	Kdo2-lipid A biosynthetic process
WG72_RS15800	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
WG72_RS15815	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
WG72_RS15820	COG1950	PFAM Membrane protein of
WG72_RS15835	COG0583	DNA-binding transcription factor activity
WG72_RS15845	COG0477	Major facilitator Superfamily
WG72_RS15860	COG0617	tRNA 3'-terminal CCA addition
WG72_RS15870	COG0513	Belongs to the DEAD box helicase family
WG72_RS15875	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
WG72_RS15890	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WG72_RS15895	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
WG72_RS15955	COG1280	lysine exporter protein (LysE YggA)
WG72_RS15970	COG0405	Gamma-glutamyltransferase
WG72_RS15980	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WG72_RS16010	COG1309	transcriptional regulator
WG72_RS16020	COG3181	Tripartite tricarboxylate transporter family receptor
WG72_RS16030	COG0745	RESPONSE REGULATOR receiver
WG72_RS16095	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
WG72_RS16120	COG0582	viral genome integration into host DNA
WG72_RS16125	COG0012	GTP binding
WG72_RS16135	COG0193	aminoacyl-tRNA hydrolase activity
WG72_RS16140	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
WG72_RS16145	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
WG72_RS16155	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
WG72_RS16160	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
WG72_RS16170	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
WG72_RS16195	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
WG72_RS16205	COG1368	sulfuric ester hydrolase activity
WG72_RS16210	COG0642	Histidine kinase
WG72_RS16215	COG0745	RESPONSE REGULATOR receiver
WG72_RS16220	COG0277	FAD linked oxidase domain protein
WG72_RS16235	COG0166	Belongs to the GPI family
WG72_RS16240	COG0438	transferase activity, transferring glycosyl groups
WG72_RS16245	COG0438	transferase activity, transferring glycosyl groups
WG72_RS16260	COG0438	transferase activity, transferring glycosyl groups
WG72_RS16275	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
WG72_RS16280	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
WG72_RS16285	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
WG72_RS16295	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
WG72_RS16305	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WG72_RS16310	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
WG72_RS16320	COG0747	negative chemotaxis
WG72_RS16325	COG0601	transmembrane transport
WG72_RS16330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WG72_RS16350	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
WG72_RS16355	COG0830	nickel cation binding
WG72_RS16365	COG0804	urea catabolic process
WG72_RS16370	COG0832	Belongs to the urease beta subunit family
WG72_RS16380	COG0831	urea catabolic process
WG72_RS16385	COG0829	nickel cation binding
WG72_RS16395	COG0633	Ferredoxin
WG72_RS16410	COG2188	Transcriptional regulator
WG72_RS16435	COG2719	SpoVR family
WG72_RS16440	COG2718	Belongs to the UPF0229 family
WG72_RS16455	COG1028	Short-chain dehydrogenase reductase Sdr
WG72_RS16460	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WG72_RS16475	COG1960	acyl-CoA dehydrogenase activity
WG72_RS16520	COG0183	Belongs to the thiolase family
WG72_RS16525	COG2030	dehydratase
WG72_RS16580	COG0328	RNA-DNA hybrid ribonuclease activity
WG72_RS16585	COG2226	methyltransferase
WG72_RS16590	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WG72_RS16595	COG1388	LysM domain
WG72_RS16595	COG0741	lytic transglycosylase activity
WG72_RS16615	COG2979	Protein of unknown function (DUF533)
WG72_RS16650	COG1271	oxidase subunit
WG72_RS16655	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
WG72_RS16660	COG0850	regulation of cytokinetic process
WG72_RS16665	COG2894	cell division
WG72_RS16670	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
WG72_RS16690	COG0488	(ABC) transporter
WG72_RS16705	COG0601	transmembrane transport
WG72_RS16715	COG1215	transferase activity, transferring glycosyl groups
WG72_RS16730	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
WG72_RS16740	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
WG72_RS16760	COG0318	PFAM AMP-dependent synthetase and ligase
WG72_RS16765	COG2188	Transcriptional regulator
WG72_RS16770	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
WG72_RS16775	COG2814	Major facilitator Superfamily
WG72_RS16785	COG0259	pyridoxamine-phosphate oxidase activity
WG72_RS16790	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
WG72_RS16805	COG0583	DNA-binding transcription factor activity
WG72_RS16810	COG1960	acyl-CoA dehydrogenase activity
WG72_RS16830	COG0134	indole-3-glycerol-phosphate synthase activity
WG72_RS16835	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
WG72_RS16840	COG0512	Glutamine amidotransferase of anthranilate synthase
WG72_RS16850	COG0546	phosphoglycolate phosphatase activity
WG72_RS16855	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
WG72_RS16860	COG2967	ApaG domain
WG72_RS16865	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
WG72_RS16870	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WG72_RS16875	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
WG72_RS16880	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
WG72_RS16890	COG0037	tRNA processing
WG72_RS16900	COG3634	alkyl hydroperoxide reductase activity
WG72_RS16905	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WG72_RS16910	COG1024	Enoyl-CoA hydratase
WG72_RS16935	COG0356	it plays a direct role in the translocation of protons across the membrane
WG72_RS16945	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
WG72_RS16950	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
WG72_RS16955	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
WG72_RS16960	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
WG72_RS16965	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
WG72_RS16970	COG0355	proton-transporting ATP synthase activity, rotational mechanism
WG72_RS16980	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
WG72_RS16985	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
WG72_RS16990	COG0210	DNA helicase
WG72_RS17000	COG2195	Cleaves the N-terminal amino acid of tripeptides
WG72_RS17010	COG4172	Belongs to the ABC transporter superfamily
WG72_RS17015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WG72_RS17020	COG0601	transmembrane transport
WG72_RS17040	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
WG72_RS17045	COG1024	Enoyl-CoA hydratase
WG72_RS17050	COG1024	Enoyl-CoA hydratase
WG72_RS17075	COG1250	3-hydroxyacyl-CoA dehydrogenase
WG72_RS17110	COG2132	Multicopper oxidase
WG72_RS17120	COG1024	Enoyl-CoA hydratase
WG72_RS17120	COG1250	3-hydroxyacyl-CoA dehydrogenase
WG72_RS17130	COG1414	Transcriptional regulator
WG72_RS17140	COG0154	amidase activity
WG72_RS17170	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WG72_RS17175	COG3568	Endonuclease Exonuclease Phosphatase
WG72_RS17180	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
WG72_RS17215	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
WG72_RS17225	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
WG72_RS17240	COG1137	ATPase activity
WG72_RS17245	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
WG72_RS17255	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
WG72_RS17260	COG1529	Aldehyde oxidase and xanthine dehydrogenase
WG72_RS17260	COG2010	Cytochrome c
WG72_RS17270	COG1660	Displays ATPase and GTPase activities
WG72_RS17275	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
WG72_RS17310	COG3181	Tripartite tricarboxylate transporter family receptor
WG72_RS17320	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
WG72_RS17325	COG2890	protein-(glutamine-N5) methyltransferase activity
WG72_RS17330	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
WG72_RS17335	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
WG72_RS17385	COG1960	acyl-CoA dehydrogenase activity
WG72_RS17395	COG0183	Belongs to the thiolase family
WG72_RS17400	COG1522	sequence-specific DNA binding
WG72_RS17405	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
WG72_RS17425	COG1024	Enoyl-CoA hydratase
WG72_RS17440	COG0604	alcohol dehydrogenase
WG72_RS17460	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
WG72_RS17470	COG1960	acyl-CoA dehydrogenase activity
WG72_RS17475	COG1960	acyl-CoA dehydrogenase activity
WG72_RS17480	COG0277	FAD linked oxidase domain protein
WG72_RS17490	COG3181	Tripartite tricarboxylate transporter family receptor
WG72_RS17515	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WG72_RS17525	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WG72_RS17530	COG3181	Tripartite tricarboxylate transporter family receptor
WG72_RS17535	COG1960	acyl-CoA dehydrogenase activity
WG72_RS17555	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
WG72_RS17560	COG1024	Enoyl-CoA hydratase
WG72_RS17565	COG1960	acyl-CoA dehydrogenase activity
WG72_RS17585	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
WG72_RS17590	COG0022	dehydrogenase e1 component
WG72_RS17595	COG1024	Enoyl-CoA hydratase
WG72_RS17600	COG0508	dehydrogenase complex catalyzes the overall conversion of
WG72_RS17620	COG0683	leucine binding
WG72_RS17625	COG0559	Belongs to the binding-protein-dependent transport system permease family
WG72_RS17630	COG0411	ABC transporter
WG72_RS17640	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WG72_RS17655	COG3181	Tripartite tricarboxylate transporter family receptor
WG72_RS17680	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
WG72_RS17685	COG0793	Belongs to the peptidase S41A family
WG72_RS17690	COG4942	peptidase
WG72_RS17695	COG0588	phosphoglycerate mutase activity
WG72_RS17700	COG1054	Belongs to the UPF0176 family
WG72_RS17705	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
WG72_RS17710	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
WG72_RS17715	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
WG72_RS17720	COG3181	Tripartite tricarboxylate transporter family receptor
WG72_RS17735	COG2226	methyltransferase
WG72_RS17740	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
WG72_RS17755	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WG72_RS17760	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
WG72_RS17785	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
WG72_RS17810	COG1335	isochorismatase
WG72_RS17815	COG2309	aminopeptidase activity
WG72_RS17820	COG0596	Alpha beta hydrolase
WG72_RS17825	COG3473	Maleate cis-trans isomerase
WG72_RS17835	COG2068	MobA-Related Protein
WG72_RS17860	COG2204	response regulator
WG72_RS17865	COG5000	phosphorelay sensor kinase activity
WG72_RS17875	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
WG72_RS17875	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
WG72_RS17885	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
WG72_RS17905	COG0583	DNA-binding transcription factor activity
WG72_RS17920	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
WG72_RS17925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WG72_RS17930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WG72_RS17945	COG0758	DNA mediated transformation
WG72_RS17950	COG1522	sequence-specific DNA binding
WG72_RS17960	COG0242	peptide deformylase activity
WG72_RS17975	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
WG72_RS17985	COG0546	phosphoglycolate phosphatase activity
WG72_RS18005	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
WG72_RS18010	COG1942	4-Oxalocrotonate Tautomerase
WG72_RS18015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WG72_RS18040	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
WG72_RS18060	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WG72_RS18065	COG1024	Enoyl-CoA hydratase
WG72_RS18070	COG1414	Transcriptional regulator
WG72_RS18075	COG0318	PFAM AMP-dependent synthetase and ligase
WG72_RS18080	COG3181	Tripartite tricarboxylate transporter family receptor
WG72_RS18110	COG0583	DNA-binding transcription factor activity
WG72_RS18125	COG3422	double-strand break repair
WG72_RS18130	COG0330	HflC and HflK could
WG72_RS18140	COG0251	oxidation-reduction process
WG72_RS18185	COG3723	Recombinational DNA repair protein, rece pathway
WG72_RS18220	COG0582	viral genome integration into host DNA
WG72_RS18245	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
WG72_RS18255	COG0706	membrane insertase activity
WG72_RS18260	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
WG72_RS18265	COG0594	ribonuclease P activity
WG72_RS18270	COG0230	Belongs to the bacterial ribosomal protein bL34 family
WG72_RS18275	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
WG72_RS18290	COG1414	Transcriptional regulator
WG72_RS18295	COG0154	amidase activity
WG72_RS18310	COG1304	FMN binding
WG72_RS18330	COG1960	acyl-CoA dehydrogenase activity
WG72_RS18350	COG1960	acyl-CoA dehydrogenase activity
WG72_RS18365	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
WG72_RS18380	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
WG72_RS18385	COG3181	Tripartite tricarboxylate transporter family receptor
WG72_RS18395	COG2358	TRAP transporter, solute receptor (TAXI family
WG72_RS18405	COG1629	transport
WG72_RS18410	COG2922	Belongs to the Smg family
WG72_RS18435	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
WG72_RS18440	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WG72_RS18445	COG1028	Short-chain dehydrogenase reductase Sdr
WG72_RS18450	COG1012	belongs to the aldehyde dehydrogenase family
WG72_RS18460	COG0028	Belongs to the TPP enzyme family
WG72_RS18465	COG1522	sequence-specific DNA binding
WG72_RS18470	COG3781	membrane
WG72_RS18480	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
WG72_RS18500	COG4206	TonB-dependent receptor
WG72_RS18505	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
WG72_RS18510	COG2022	thiamine diphosphate biosynthetic process
WG72_RS18515	COG0351	phosphomethylpyrimidine kinase
WG72_RS18520	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
WG72_RS18535	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
WG72_RS18545	COG0628	permease
WG72_RS18555	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
WG72_RS18565	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
WG72_RS18570	COG0049	tRNA binding
WG72_RS18575	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
WG72_RS18580	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
WG72_RS18585	COG0051	transcription antitermination factor activity, RNA binding
WG72_RS18590	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
WG72_RS18595	COG0088	Forms part of the polypeptide exit tunnel
WG72_RS18600	COG0089	rRNA binding
WG72_RS18605	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
WG72_RS18610	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
WG72_RS18615	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
WG72_RS18620	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
WG72_RS18625	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
WG72_RS18630	COG0255	Belongs to the universal ribosomal protein uL29 family
WG72_RS18635	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
WG72_RS18655	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
WG72_RS18660	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
WG72_RS18665	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
WG72_RS18670	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
WG72_RS18675	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
WG72_RS18680	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
WG72_RS18685	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
WG72_RS18690	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
WG72_RS18695	COG1841	ribosomal large subunit assembly
WG72_RS18700	COG0200	Binds to the 23S rRNA
WG72_RS18705	COG0201	protein transport
WG72_RS18710	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
WG72_RS18715	COG0257	Belongs to the bacterial ribosomal protein bL36 family
WG72_RS18720	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
WG72_RS18725	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
WG72_RS18730	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
WG72_RS18735	COG0202	RNA polymerase activity
WG72_RS18740	COG0203	ribosomal protein L17
WG72_RS18745	COG0537	adenosine 5'-monophosphoramidase activity
WG72_RS18750	COG1324	tolerance protein
WG72_RS18755	COG4232	protein-disulfide reductase activity
WG72_RS18770	COG0218	Necessary for normal cell division and for the maintenance of normal septation
WG72_RS18780	COG1333	cytochrome c biogenesis protein
WG72_RS18785	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
WG72_RS18800	COG1965	Belongs to the frataxin family
WG72_RS18810	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
WG72_RS18815	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
WG72_RS18820	COG0232	Belongs to the dGTPase family. Type 2 subfamily
WG72_RS18835	COG2814	Major facilitator Superfamily
WG72_RS18840	COG0629	single-stranded DNA binding
WG72_RS18880	COG0402	S-adenosylhomocysteine deaminase activity
WG72_RS18890	COG0438	transferase activity, transferring glycosyl groups
WG72_RS18910	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WG72_RS18935	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
WG72_RS18940	COG2186	Transcriptional regulator
WG72_RS18960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WG72_RS18965	COG1956	GAF domain-containing protein
WG72_RS18970	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WG72_RS18985	COG1652	LysM domain
WG72_RS19000	COG0220	tRNA (guanine-N7-)-methyltransferase activity
WG72_RS19015	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
WG72_RS19045	COG3181	Tripartite tricarboxylate transporter family receptor
WG72_RS19060	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WG72_RS19075	COG1024	Enoyl-CoA hydratase
WG72_RS19090	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WG72_RS19095	COG1309	transcriptional regulator
WG72_RS19100	COG2816	NAD+ diphosphatase activity
WG72_RS19105	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WG72_RS19190	COG2814	Major facilitator Superfamily
WG72_RS19195	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
WG72_RS19215	COG1999	signal sequence binding
WG72_RS19220	COG0109	protoheme IX farnesyltransferase activity
WG72_RS19260	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
WG72_RS19280	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
WG72_RS19285	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
WG72_RS19295	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
WG72_RS19300	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
WG72_RS19310	COG0067	glutamate synthase
WG72_RS19310	COG0070	glutamate synthase
WG72_RS19310	COG0069	glutamate synthase activity
WG72_RS19320	COG3047	cAMP biosynthetic process
WG72_RS19330	COG1127	ABC transporter
WG72_RS19335	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
WG72_RS19340	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
WG72_RS19345	COG2853	Lipoprotein
WG72_RS19355	COG1131	(ABC) transporter
WG72_RS19360	COG0842	Transport permease protein
WG72_RS19370	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
WG72_RS19375	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
WG72_RS19380	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
WG72_RS19385	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
WG72_RS19390	COG0131	Imidazoleglycerol-phosphate dehydratase
WG72_RS19395	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
WG72_RS19400	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
WG72_RS19405	COG0107	imidazoleglycerol-phosphate synthase activity
WG72_RS19410	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
WG72_RS19415	COG0140	phosphoribosyl-ATP diphosphatase activity
WG72_RS19420	COG0537	adenosine 5'-monophosphoramidase activity
WG72_RS19425	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
WG72_RS19430	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
WG72_RS19445	COG3181	Tripartite tricarboxylate transporter family receptor
WG72_RS19480	COG3702	type iv secretory pathway
WG72_RS19485	COG3451	type IV secretory pathway VirB4
WG72_RS19500	COG3736	Type IV secretory pathway, component VirB8
WG72_RS19505	COG3504	Conjugal transfer protein
WG72_RS19510	COG2948	multi-organism process
WG72_RS19515	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
WG72_RS19525	COG0697	spore germination
WG72_RS19545	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
WG72_RS19550	COG0747	negative chemotaxis
WG72_RS19555	COG0601	transmembrane transport
WG72_RS19560	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WG72_RS19565	COG0444	Belongs to the ABC transporter superfamily
WG72_RS19575	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
WG72_RS19585	COG0494	nUDIX hydrolase
WG72_RS19625	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
WG72_RS19630	COG0237	dephospho-CoA kinase activity
WG72_RS19635	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
WG72_RS19650	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
WG72_RS19655	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
WG72_RS19665	COG0477	Major facilitator Superfamily
WG72_RS19670	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
WG72_RS19685	COG1126	abc transporter atp-binding protein
WG72_RS19690	COG0765	amino acid transport
WG72_RS19695	COG4597	amino acid ABC transporter
WG72_RS19700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WG72_RS19705	COG2884	Cell division ATP-binding protein ftsE
WG72_RS19710	COG2177	Part of the ABC transporter FtsEX involved in
WG72_RS19715	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
WG72_RS19725	COG1194	a g-specific adenine glycosylase
WG72_RS19735	COG2226	methyltransferase
WG72_RS19745	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WG72_RS19750	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WG72_RS19765	COG1024	Enoyl-CoA hydratase
WG72_RS19785	COG1024	Enoyl-CoA hydratase
WG72_RS19790	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WG72_RS19795	COG3181	Tripartite tricarboxylate transporter family receptor
WG72_RS19805	COG0753	catalase activity
WG72_RS19810	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WG72_RS19815	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
WG72_RS19825	COG2175	clavaminate synthase activity
WG72_RS19830	COG1473	amidohydrolase
WG72_RS19835	COG4608	Belongs to the ABC transporter superfamily
WG72_RS19840	COG0444	Belongs to the ABC transporter superfamily
WG72_RS19855	COG0747	negative chemotaxis
WG72_RS19860	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
WG72_RS19895	COG0436	Aminotransferase
WG72_RS19900	COG1278	Cold shock