locus-tag	class	description
BFW76_RS00005	COG0445	tRNA wobble uridine modification
BFW76_RS00010	COG0357	Ribosomal RNA small subunit methyltransferase G
BFW76_RS00015	COG1192	Involved in chromosome partitioning
BFW76_RS00025	COG1475	DNA binding
BFW76_RS00050	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BFW76_RS00060	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BFW76_RS00070	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BFW76_RS00075	COG0081	regulation of translation
BFW76_RS00080	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BFW76_RS00085	COG0222	ribosome binding
BFW76_RS00090	COG0085	RNA polymerase activity
BFW76_RS00095	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BFW76_RS00135	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BFW76_RS00160	COG1024	Enoyl-CoA hydratase
BFW76_RS00180	COG0752	glycyl-tRNA synthetase alpha subunit
BFW76_RS00185	COG0751	glycine-tRNA ligase activity
BFW76_RS00190	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BFW76_RS00195	COG0204	Acyl-transferase
BFW76_RS00210	COG0242	peptide deformylase activity
BFW76_RS00245	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BFW76_RS00250	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BFW76_RS00255	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BFW76_RS00255	COG2813	Specifically methylates the guanine in position
BFW76_RS00270	COG2223	nitrite transmembrane transporter activity
BFW76_RS00280	COG1794	racemase activity, acting on amino acids and derivatives
BFW76_RS00285	COG1126	abc transporter atp-binding protein
BFW76_RS00290	COG0765	amino acid transport
BFW76_RS00295	COG0765	amino acid transport
BFW76_RS00300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BFW76_RS00365	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BFW76_RS00395	COG0326	Molecular chaperone. Has ATPase activity
BFW76_RS00400	COG0625	glutathione transferase activity
BFW76_RS00415	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BFW76_RS00420	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BFW76_RS00450	COG0438	transferase activity, transferring glycosyl groups
BFW76_RS00455	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BFW76_RS00460	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BFW76_RS00490	COG0859	PFAM glycosyl transferase family 9
BFW76_RS00505	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BFW76_RS00515	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BFW76_RS00520	COG1127	ABC transporter
BFW76_RS00540	COG1686	Belongs to the peptidase S11 family
BFW76_RS00550	COG2921	Belongs to the UPF0250 family
BFW76_RS00555	COG0321	lipoyl(octanoyl) transferase activity
BFW76_RS00560	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BFW76_RS00595	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BFW76_RS00605	COG0018	arginyl-trna synthetase
BFW76_RS00625	COG0395	ABC-type sugar transport system, permease component
BFW76_RS00630	COG1175	transmembrane transport
BFW76_RS00635	COG1653	transport
BFW76_RS00640	COG3842	ATPase activity
BFW76_RS00645	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BFW76_RS00655	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BFW76_RS00675	COG1609	Transcriptional regulator
BFW76_RS00685	COG0154	amidase activity
BFW76_RS00690	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BFW76_RS00700	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BFW76_RS00710	COG0583	DNA-binding transcription factor activity
BFW76_RS00725	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BFW76_RS00730	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BFW76_RS00745	COG1802	Transcriptional regulator
BFW76_RS00760	COG1024	Enoyl-CoA hydratase
BFW76_RS00775	COG3181	Tripartite tricarboxylate transporter family receptor
BFW76_RS00790	COG1984	allophanate hydrolase subunit 2
BFW76_RS00795	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BFW76_RS00805	COG0583	DNA-binding transcription factor activity
BFW76_RS00810	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BFW76_RS00820	COG5002	protein histidine kinase activity
BFW76_RS00830	COG5002	protein histidine kinase activity
BFW76_RS00835	COG0745	RESPONSE REGULATOR receiver
BFW76_RS00840	COG2226	methyltransferase
BFW76_RS00855	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BFW76_RS00875	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BFW76_RS00885	COG0513	Belongs to the DEAD box helicase family
BFW76_RS00890	COG1280	lysine exporter protein (LysE YggA)
BFW76_RS00895	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BFW76_RS00930	COG1054	Belongs to the UPF0176 family
BFW76_RS00935	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BFW76_RS00935	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BFW76_RS00945	COG0489	protein tyrosine kinase activity
BFW76_RS00960	COG0717	Belongs to the dCTP deaminase family
BFW76_RS00990	COG2081	HI0933 family
BFW76_RS01000	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BFW76_RS01010	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BFW76_RS01015	COG0509	glycine decarboxylation via glycine cleavage system
BFW76_RS01020	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BFW76_RS01020	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BFW76_RS01060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BFW76_RS01075	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BFW76_RS01085	COG1414	Transcriptional regulator
BFW76_RS01090	COG1028	Short-chain dehydrogenase reductase Sdr
BFW76_RS01095	COG2031	fatty acid transporter
BFW76_RS01100	COG1250	3-hydroxyacyl-CoA dehydrogenase
BFW76_RS01110	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BFW76_RS01115	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BFW76_RS01125	COG4257	antibiotic catabolic process
BFW76_RS01150	COG1012	belongs to the aldehyde dehydrogenase family
BFW76_RS01155	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BFW76_RS01160	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BFW76_RS01185	COG1028	Short-chain dehydrogenase reductase Sdr
BFW76_RS01195	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BFW76_RS01205	COG2188	Transcriptional regulator
BFW76_RS01210	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BFW76_RS01235	COG0617	tRNA 3'-terminal CCA addition
BFW76_RS01250	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BFW76_RS01255	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BFW76_RS01260	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BFW76_RS01265	COG0586	Pfam SNARE associated Golgi protein
BFW76_RS01270	COG0860	N-Acetylmuramoyl-L-alanine amidase
BFW76_RS01275	COG0802	atpase or kinase
BFW76_RS01280	COG0114	fumarate hydratase activity
BFW76_RS01290	COG3181	Tripartite tricarboxylate transporter family receptor
BFW76_RS01300	COG0405	Gamma-glutamyltransferase
BFW76_RS01305	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BFW76_RS01315	COG1960	acyl-CoA dehydrogenase activity
BFW76_RS01340	COG1294	oxidase, subunit
BFW76_RS01350	COG4988	ABC transporter
BFW76_RS01355	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BFW76_RS01375	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BFW76_RS01405	COG2969	positive regulation of protein catabolic process
BFW76_RS01410	COG0625	glutathione transferase activity
BFW76_RS01415	COG2857	Cytochrome c1
BFW76_RS01420	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BFW76_RS01425	COG0723	plastoquinol--plastocyanin reductase activity
BFW76_RS01430	COG1970	mechanosensitive ion channel activity
BFW76_RS01435	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BFW76_RS01450	COG2808	Putative FMN-binding domain
BFW76_RS01455	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BFW76_RS01460	COG0747	negative chemotaxis
BFW76_RS01465	COG0657	acetylesterase activity
BFW76_RS01475	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BFW76_RS01480	COG2207	Transcriptional regulator
BFW76_RS01485	COG0129	dihydroxy-acid dehydratase activity
BFW76_RS01490	COG2814	Major facilitator Superfamily
BFW76_RS01495	COG0583	DNA-binding transcription factor activity
BFW76_RS01505	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
BFW76_RS01575	COG1024	Enoyl-CoA hydratase
BFW76_RS01580	COG1960	acyl-CoA dehydrogenase activity
BFW76_RS01605	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BFW76_RS01610	COG0352	thiamine-phosphate diphosphorylase activity
BFW76_RS01625	COG1678	Uncharacterized ACR, COG1678
BFW76_RS01630	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BFW76_RS01635	COG0540	Belongs to the ATCase OTCase family
BFW76_RS01650	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BFW76_RS01660	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BFW76_RS01695	COG1234	tRNA 3'-trailer cleavage
BFW76_RS01705	COG0583	DNA-binding transcription factor activity
BFW76_RS01715	COG3064	Membrane
BFW76_RS01745	COG1683	Conserved Protein
BFW76_RS01750	COG1120	ATPase activity
BFW76_RS01755	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BFW76_RS01760	COG4558	Periplasmic binding protein
BFW76_RS01765	COG3720	iron ion transport
BFW76_RS01775	COG3712	iron ion homeostasis
BFW76_RS01780	COG1595	DNA-templated transcription, initiation
BFW76_RS01815	COG1802	Transcriptional regulator
BFW76_RS01825	COG3069	C4-dicarboxylate transmembrane transporter activity
BFW76_RS01835	COG1012	belongs to the aldehyde dehydrogenase family
BFW76_RS01870	COG2860	membrane
BFW76_RS01875	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BFW76_RS01880	COG0708	Exodeoxyribonuclease III
BFW76_RS01885	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BFW76_RS01890	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BFW76_RS01895	COG0154	amidase activity
BFW76_RS01900	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BFW76_RS01905	COG1077	Cell shape determining protein MreB Mrl
BFW76_RS01910	COG1792	Involved in formation and maintenance of cell shape
BFW76_RS01920	COG0768	penicillin binding
BFW76_RS01925	COG0772	Belongs to the SEDS family
BFW76_RS01930	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BFW76_RS01935	COG0471	metal ion transport
BFW76_RS01940	COG1309	transcriptional regulator
BFW76_RS01950	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BFW76_RS01965	COG2823	Periplasmic or secreted lipoprotein
BFW76_RS01970	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BFW76_RS01985	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BFW76_RS02005	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BFW76_RS02015	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BFW76_RS02035	COG0492	ferredoxin-NADP+ reductase activity
BFW76_RS02045	COG3181	Tripartite tricarboxylate transporter family receptor
BFW76_RS02050	COG1024	Enoyl-CoA hydratase
BFW76_RS02050	COG1250	3-hydroxyacyl-CoA dehydrogenase
BFW76_RS02055	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BFW76_RS02060	COG0028	Belongs to the TPP enzyme family
BFW76_RS02085	COG3181	Tripartite tricarboxylate transporter family receptor
BFW76_RS02095	COG0697	spore germination
BFW76_RS02125	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BFW76_RS02130	COG0463	Glycosyl transferase, family 2
BFW76_RS02145	COG0786	glutamate:sodium symporter activity
BFW76_RS02155	COG2031	fatty acid transporter
BFW76_RS02170	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BFW76_RS02175	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BFW76_RS02185	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BFW76_RS02200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BFW76_RS02210	COG1285	pathogenesis
BFW76_RS02215	COG1253	flavin adenine dinucleotide binding
BFW76_RS02220	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BFW76_RS02225	COG1024	Enoyl-CoA hydratase
BFW76_RS02230	COG3181	Tripartite tricarboxylate transporter family receptor
BFW76_RS02235	COG0583	DNA-binding transcription factor activity
BFW76_RS02240	COG1960	acyl-CoA dehydrogenase activity
BFW76_RS02250	COG0183	Belongs to the thiolase family
BFW76_RS02270	COG0583	DNA-binding transcription factor activity
BFW76_RS02275	COG1278	Cold shock
BFW76_RS02285	COG1802	Transcriptional regulator
BFW76_RS02290	COG1012	belongs to the aldehyde dehydrogenase family
BFW76_RS02295	COG2031	fatty acid transporter
BFW76_RS02300	COG1017	nitric oxide dioxygenase activity
BFW76_RS02300	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BFW76_RS02305	COG0251	oxidation-reduction process
BFW76_RS02325	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BFW76_RS02335	COG0583	DNA-binding transcription factor activity
BFW76_RS02340	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BFW76_RS02350	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
BFW76_RS02355	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BFW76_RS02360	COG0546	phosphoglycolate phosphatase activity
BFW76_RS02370	COG1530	ribonuclease E activity
BFW76_RS02385	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BFW76_RS02390	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BFW76_RS02395	COG0159	tryptophan synthase activity
BFW76_RS02400	COG0133	tryptophan synthase activity
BFW76_RS02410	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BFW76_RS02415	COG3228	Belongs to the MtfA family
BFW76_RS02425	COG0251	oxidation-reduction process
BFW76_RS02430	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BFW76_RS02435	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BFW76_RS02450	COG2878	Part of a membrane complex involved in electron transport
BFW76_RS02455	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BFW76_RS02490	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BFW76_RS02510	COG1268	BioY protein
BFW76_RS02515	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BFW76_RS02520	COG1122	ATPase activity
BFW76_RS02525	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BFW76_RS02540	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BFW76_RS02545	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BFW76_RS02555	COG1196	nuclear chromosome segregation
BFW76_RS02560	COG0477	Major facilitator Superfamily
BFW76_RS02565	COG1573	uracil-dna glycosylase
BFW76_RS02570	COG1214	PFAM Peptidase M22, glycoprotease
BFW76_RS02595	COG0450	alkyl hydroperoxide reductase
BFW76_RS02600	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BFW76_RS02610	COG2223	nitrite transmembrane transporter activity
BFW76_RS02620	COG2186	Transcriptional regulator
BFW76_RS02640	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BFW76_RS02650	COG0583	DNA-binding transcription factor activity
BFW76_RS02660	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BFW76_RS02665	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BFW76_RS02670	COG0137	argininosuccinate synthase activity
BFW76_RS02675	COG3158	transport of potassium into the cell
BFW76_RS02680	COG0642	Histidine kinase
BFW76_RS02710	COG0776	regulation of translation
BFW76_RS02715	COG3128	pkhd-type hydroxylase
BFW76_RS02725	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BFW76_RS02730	COG0557	exoribonuclease II activity
BFW76_RS02755	COG0679	Auxin Efflux Carrier
BFW76_RS02760	COG2391	methyltransferase activity
BFW76_RS02765	COG0069	glutamate synthase activity
BFW76_RS02775	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BFW76_RS02785	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
BFW76_RS02790	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BFW76_RS02825	COG3706	GGDEF domain
BFW76_RS02850	COG1053	succinate dehydrogenase
BFW76_RS02855	COG0583	DNA-binding transcription factor activity
BFW76_RS02865	COG1053	succinate dehydrogenase
BFW76_RS02885	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BFW76_RS02890	COG0459	protein refolding
BFW76_RS02895	COG3468	outer membrane autotransporter barrel domain protein
BFW76_RS02910	COG1252	NADH dehydrogenase
BFW76_RS02915	COG0284	orotidine-5'-phosphate decarboxylase activity
BFW76_RS02920	COG1058	Belongs to the CinA family
BFW76_RS02920	COG1546	Belongs to the CinA family
BFW76_RS02925	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BFW76_RS02935	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BFW76_RS02940	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BFW76_RS02975	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BFW76_RS02980	COG3639	organic phosphonate transmembrane transporter activity
BFW76_RS02985	COG3639	organic phosphonate transmembrane transporter activity
BFW76_RS03005	COG0742	ribosomal rna small subunit methyltransferase
BFW76_RS03010	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BFW76_RS03015	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BFW76_RS03020	COG3135	benzoate transporter
BFW76_RS03035	COG0640	Transcriptional regulator
BFW76_RS03065	COG4172	Belongs to the ABC transporter superfamily
BFW76_RS03070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BFW76_RS03075	COG0601	transmembrane transport
BFW76_RS03085	COG0280	phosphate acetyltransferase
BFW76_RS03085	COG0281	malic enzyme
BFW76_RS03145	COG0583	DNA-binding transcription factor activity
BFW76_RS03155	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BFW76_RS03160	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BFW76_RS03165	COG0167	dihydroorotate dehydrogenase activity
BFW76_RS03185	COG1414	Transcriptional regulator
BFW76_RS03190	COG1546	Belongs to the CinA family
BFW76_RS03190	COG1058	Belongs to the CinA family
BFW76_RS03210	COG0513	Belongs to the DEAD box helicase family
BFW76_RS03240	COG0429	hydrolase of the alpha beta-hydrolase fold
BFW76_RS03245	COG4783	chaperone-mediated protein folding
BFW76_RS03260	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BFW76_RS03285	COG0006	proline dipeptidase activity
BFW76_RS03295	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BFW76_RS03315	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BFW76_RS03320	COG0632	four-way junction helicase activity
BFW76_RS03335	COG2255	four-way junction helicase activity
BFW76_RS03340	COG0514	ATP-dependent DNA helicase (RecQ)
BFW76_RS03355	COG0288	reversible hydration of carbon dioxide
BFW76_RS03360	COG0154	amidase activity
BFW76_RS03370	COG4211	Belongs to the binding-protein-dependent transport system permease family
BFW76_RS03400	COG1464	Belongs to the NlpA lipoprotein family
BFW76_RS03545	COG1196	nuclear chromosome segregation
BFW76_RS03615	COG2135	peptidase activity
BFW76_RS03630	COG0494	nUDIX hydrolase
BFW76_RS03635	COG0442	prolyl-tRNA aminoacylation
BFW76_RS03640	COG0824	Thioesterase
BFW76_RS03645	COG0811	peptide transport
BFW76_RS03650	COG0848	biopolymer transport protein
BFW76_RS03660	COG0823	Involved in the tonB-independent uptake of proteins
BFW76_RS03675	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BFW76_RS03680	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BFW76_RS03715	COG0700	Nucleoside recognition
BFW76_RS03720	COG0469	pyruvate kinase activity
BFW76_RS03725	COG1929	Belongs to the glycerate kinase type-1 family
BFW76_RS03730	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BFW76_RS03735	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BFW76_RS03740	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BFW76_RS03750	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BFW76_RS03760	COG2154	pterin-4-alpha-carbinolamine dehydratase
BFW76_RS03785	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BFW76_RS03790	COG0154	amidase activity
BFW76_RS03800	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BFW76_RS03805	COG0601	transmembrane transport
BFW76_RS03810	COG0747	negative chemotaxis
BFW76_RS03830	COG0019	diaminopimelate decarboxylase activity
BFW76_RS03845	COG2353	YceI-like domain
BFW76_RS03850	COG4774	siderophore transport
BFW76_RS03855	COG3712	iron ion homeostasis
BFW76_RS03895	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BFW76_RS03900	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BFW76_RS03905	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BFW76_RS03910	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BFW76_RS03920	COG0142	geranyltranstransferase activity
BFW76_RS03930	COG0583	DNA-binding transcription factor activity
BFW76_RS03940	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
BFW76_RS03945	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BFW76_RS03960	COG2994	toxin metabolic process
BFW76_RS03970	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
BFW76_RS03975	COG2274	protein secretion by the type I secretion system
BFW76_RS03980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BFW76_RS03985	COG1538	Outer membrane efflux protein
BFW76_RS04000	COG0765	amino acid transport
BFW76_RS04005	COG0765	amino acid transport
BFW76_RS04010	COG1126	abc transporter atp-binding protein
BFW76_RS04030	COG1028	Short-chain dehydrogenase reductase Sdr
BFW76_RS04040	COG1802	Transcriptional regulator
BFW76_RS04050	COG1802	Transcriptional regulator
BFW76_RS04060	COG0318	PFAM AMP-dependent synthetase and ligase
BFW76_RS04070	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BFW76_RS04090	COG0028	Belongs to the TPP enzyme family
BFW76_RS04110	COG0308	aminopeptidase N
BFW76_RS04115	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BFW76_RS04130	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BFW76_RS04135	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BFW76_RS04140	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BFW76_RS04145	COG0560	Phosphoserine phosphatase
BFW76_RS04150	COG0583	DNA-binding transcription factor activity
BFW76_RS04155	COG3181	Tripartite tricarboxylate transporter family receptor
BFW76_RS04160	COG0028	Belongs to the TPP enzyme family
BFW76_RS04175	COG4774	siderophore transport
BFW76_RS04180	COG4774	siderophore transport
BFW76_RS04190	COG1007	ATP synthesis coupled electron transport
BFW76_RS04205	COG0713	ATP synthesis coupled electron transport
BFW76_RS04215	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BFW76_RS04220	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BFW76_RS04225	COG1034	ATP synthesis coupled electron transport
BFW76_RS04235	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BFW76_RS04240	COG0649	NAD binding
BFW76_RS04245	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BFW76_RS04250	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BFW76_RS04255	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BFW76_RS04260	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BFW76_RS04290	COG0671	phosphoesterase, PA-phosphatase related
BFW76_RS04300	COG1597	lipid kinase activity
BFW76_RS04305	COG0583	DNA-binding transcription factor activity
BFW76_RS04310	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BFW76_RS04320	COG1733	regulation of RNA biosynthetic process
BFW76_RS04325	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BFW76_RS04330	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BFW76_RS04345	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
BFW76_RS04365	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BFW76_RS04385	COG3608	succinylglutamate desuccinylase aspartoacylase
BFW76_RS04390	COG0626	cystathionine gamma-synthase activity
BFW76_RS04395	COG0583	DNA-binding transcription factor activity
BFW76_RS04430	COG3799	methylaspartate ammonia-lyase activity
BFW76_RS04440	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BFW76_RS04450	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BFW76_RS04455	COG0149	triose-phosphate isomerase activity
BFW76_RS04475	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BFW76_RS04490	COG1185	polyribonucleotide nucleotidyltransferase activity
BFW76_RS04495	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BFW76_RS04510	COG1183	phosphatidylcholine synthase activity
BFW76_RS04515	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BFW76_RS04520	COG0440	acetolactate synthase activity
BFW76_RS04525	COG0028	Belongs to the TPP enzyme family
BFW76_RS04540	COG5265	(ABC) transporter
BFW76_RS04545	COG0500	methyltransferase
BFW76_RS04565	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
BFW76_RS04585	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BFW76_RS04595	COG0511	ligase activity, forming carbon-carbon bonds
BFW76_RS04620	COG2188	Transcriptional regulator
BFW76_RS04625	COG0439	Biotin carboxylase
BFW76_RS04630	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BFW76_RS04675	COG5265	(ABC) transporter
BFW76_RS04685	COG0667	Aldo Keto reductase
BFW76_RS04700	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BFW76_RS04740	COG0583	DNA-binding transcription factor activity
BFW76_RS04770	COG2814	Major facilitator Superfamily
BFW76_RS04780	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BFW76_RS04795	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BFW76_RS04805	COG0287	Prephenate dehydrogenase
BFW76_RS04810	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BFW76_RS04815	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BFW76_RS04835	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BFW76_RS04840	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BFW76_RS04845	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BFW76_RS04850	COG1596	polysaccharide export
BFW76_RS04850	COG1555	photosystem II stabilization
BFW76_RS04865	COG2951	lytic endotransglycosylase activity
BFW76_RS04870	COG0123	including yeast histone deacetylase and acetoin utilization protein
BFW76_RS04885	COG1960	acyl-CoA dehydrogenase activity
BFW76_RS04890	COG0450	alkyl hydroperoxide reductase
BFW76_RS04910	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BFW76_RS04940	COG0335	large ribosomal subunit rRNA binding
BFW76_RS04955	COG0667	Aldo Keto reductase
BFW76_RS04965	COG2814	Major facilitator Superfamily
BFW76_RS04970	COG3161	chorismate lyase activity
BFW76_RS04975	COG1187	pseudouridine synthase activity
BFW76_RS04985	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BFW76_RS05005	COG1999	signal sequence binding
BFW76_RS05010	COG0339	signal peptide processing
BFW76_RS05015	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BFW76_RS05020	COG4566	intracellular signal transduction
BFW76_RS05030	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BFW76_RS05035	COG0508	dehydrogenase complex catalyzes the overall conversion of
BFW76_RS05040	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BFW76_RS05045	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BFW76_RS05055	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BFW76_RS05060	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BFW76_RS05065	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BFW76_RS05070	COG0126	phosphoglycerate kinase activity
BFW76_RS05075	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BFW76_RS05080	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BFW76_RS05095	COG0625	glutathione transferase activity
BFW76_RS05130	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BFW76_RS05140	COG0521	Mo-molybdopterin cofactor biosynthetic process
BFW76_RS05150	COG0739	heme binding
BFW76_RS05160	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BFW76_RS05195	COG0745	RESPONSE REGULATOR receiver
BFW76_RS05210	COG0840	transmembrane signaling receptor activity
BFW76_RS05220	COG2201	protein-glutamate methylesterase activity
BFW76_RS05225	COG0745	RESPONSE REGULATOR receiver
BFW76_RS05230	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
BFW76_RS05255	COG0667	Aldo Keto reductase
BFW76_RS05265	COG4535	Mg2 and Co2 transporter CorC
BFW76_RS05270	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BFW76_RS05275	COG1702	phosphate starvation-inducible protein PhoH
BFW76_RS05280	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BFW76_RS05295	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BFW76_RS05300	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BFW76_RS05305	COG1862	Preprotein translocase
BFW76_RS05310	COG0343	queuine tRNA-ribosyltransferase activity
BFW76_RS05315	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BFW76_RS05320	COG2027	D-alanyl-D-alanine carboxypeptidase
BFW76_RS05325	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BFW76_RS05335	COG3468	outer membrane autotransporter barrel domain protein
BFW76_RS05340	COG1648	precorrin-2 dehydrogenase activity
BFW76_RS05340	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BFW76_RS05365	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BFW76_RS05370	COG0741	lytic transglycosylase activity
BFW76_RS05375	COG0436	Aminotransferase
BFW76_RS05385	COG0281	malic enzyme
BFW76_RS05385	COG0280	phosphate acetyltransferase
BFW76_RS05395	COG2732	(Barnase) inhibitor
BFW76_RS05410	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BFW76_RS05435	COG0248	Ppx GppA phosphatase
BFW76_RS05445	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BFW76_RS05455	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BFW76_RS05460	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BFW76_RS05465	COG1534	Rna-binding protein
BFW76_RS05495	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BFW76_RS05510	COG1295	ribonuclease BN
BFW76_RS05520	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BFW76_RS05525	COG0745	RESPONSE REGULATOR receiver
BFW76_RS05530	COG2205	protein histidine kinase activity
BFW76_RS05565	COG1022	Amp-dependent synthetase and ligase
BFW76_RS05580	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BFW76_RS05585	COG1028	Short-chain dehydrogenase reductase Sdr
BFW76_RS05595	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BFW76_RS05610	COG1136	(ABC) transporter
BFW76_RS05615	COG0084	hydrolase, TatD family'
BFW76_RS05645	COG2333	competence protein COMEC
BFW76_RS05645	COG0658	competence protein
BFW76_RS05655	COG0613	PHP domain protein
BFW76_RS05675	COG3539	Fimbrial protein
BFW76_RS05680	COG0281	malic enzyme
BFW76_RS05680	COG0280	phosphate acetyltransferase
BFW76_RS05690	COG1522	sequence-specific DNA binding
BFW76_RS05700	COG0567	Dehydrogenase, E1 component
BFW76_RS05705	COG0508	dehydrogenase complex catalyzes the overall conversion of
BFW76_RS05710	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BFW76_RS05715	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BFW76_RS05720	COG1028	Short-chain dehydrogenase reductase Sdr
BFW76_RS05725	COG0583	DNA-binding transcription factor activity
BFW76_RS05735	COG3181	Tripartite tricarboxylate transporter family receptor
BFW76_RS05760	COG0180	Tryptophanyl-tRNA synthetase
BFW76_RS05765	COG2183	response to ionizing radiation
BFW76_RS05770	COG1199	ATP-dependent helicase activity
BFW76_RS05780	COG0564	pseudouridine synthase activity
BFW76_RS05790	COG3243	poly(R)-hydroxyalkanoic acid synthase
BFW76_RS05795	COG1028	Short-chain dehydrogenase reductase Sdr
BFW76_RS05800	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
BFW76_RS05815	COG0672	)-iron permease
BFW76_RS05855	COG0583	DNA-binding transcription factor activity
BFW76_RS05865	COG2814	Major facilitator Superfamily
BFW76_RS05880	COG1619	proteins homologs of microcin C7 resistance protein MccF
BFW76_RS05895	COG2084	Dehydrogenase
BFW76_RS05900	COG3181	Tripartite tricarboxylate transporter family receptor
BFW76_RS05925	COG2988	succinylglutamate desuccinylase activity
BFW76_RS05955	COG0765	amino acid transport
BFW76_RS05960	COG0765	amino acid transport
BFW76_RS05965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BFW76_RS06000	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BFW76_RS06005	COG1595	DNA-templated transcription, initiation
BFW76_RS06015	COG3530	Putative quorum-sensing-regulated virulence factor
BFW76_RS06020	COG0494	nUDIX hydrolase
BFW76_RS06035	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BFW76_RS06040	COG0542	response to heat
BFW76_RS06050	COG3468	outer membrane autotransporter barrel domain protein
BFW76_RS06055	COG3468	outer membrane autotransporter barrel domain protein
BFW76_RS06065	COG5441	Belongs to the UPF0261 family
BFW76_RS06070	COG5564	TIM-barrel signal transduction protein
BFW76_RS06085	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BFW76_RS06100	COG1477	protein flavinylation
BFW76_RS06120	COG1131	(ABC) transporter
BFW76_RS06125	COG0842	Transport permease protein
BFW76_RS06135	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BFW76_RS06140	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
BFW76_RS06140	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
BFW76_RS06145	COG1562	ergosterol biosynthetic process
BFW76_RS06150	COG1562	ergosterol biosynthetic process
BFW76_RS06155	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BFW76_RS06160	COG1028	Short-chain dehydrogenase reductase Sdr
BFW76_RS06180	COG2304	oxidoreductase activity
BFW76_RS06200	COG0534	Mate efflux family protein
BFW76_RS06210	COG0254	rRNA binding
BFW76_RS06215	COG3483	tryptophan 2,3-dioxygenase activity
BFW76_RS06220	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BFW76_RS06225	COG2003	Belongs to the UPF0758 family
BFW76_RS06230	COG1047	Peptidyl-prolyl cis-trans
BFW76_RS06235	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BFW76_RS06240	COG0625	glutathione transferase activity
BFW76_RS06260	COG0523	cobalamin synthesis protein
BFW76_RS06270	COG0583	DNA-binding transcription factor activity
BFW76_RS06280	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BFW76_RS06285	COG1187	pseudouridine synthase activity
BFW76_RS06290	COG0779	Required for maturation of 30S ribosomal subunits
BFW76_RS06295	COG0195	Participates in both transcription termination and antitermination
BFW76_RS06295	COG2251	uridine kinase activity
BFW76_RS06300	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BFW76_RS06305	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BFW76_RS06310	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BFW76_RS06330	COG1611	Belongs to the LOG family
BFW76_RS06345	COG0412	Dienelactone hydrolase
BFW76_RS06350	COG1283	sodium-dependent phosphate transmembrane transporter activity
BFW76_RS06355	COG1760	l-serine dehydratase
BFW76_RS06360	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BFW76_RS06365	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BFW76_RS06375	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BFW76_RS06400	COG2311	Membrane
BFW76_RS06410	COG0697	spore germination
BFW76_RS06425	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BFW76_RS06445	COG0559	Belongs to the binding-protein-dependent transport system permease family
BFW76_RS06460	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BFW76_RS06470	COG1653	transport
BFW76_RS06475	COG1175	transmembrane transport
BFW76_RS06480	COG0395	ABC-type sugar transport system, permease component
BFW76_RS06485	COG3842	ATPase activity
BFW76_RS06510	COG2363	Small membrane protein
BFW76_RS06525	COG1464	Belongs to the NlpA lipoprotein family
BFW76_RS06535	COG0688	phosphatidylethanolamine metabolic process
BFW76_RS06550	COG0095	Lipoate-protein ligase
BFW76_RS06565	COG0625	glutathione transferase activity
BFW76_RS06570	COG0386	Belongs to the glutathione peroxidase family
BFW76_RS06590	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BFW76_RS06620	COG2259	Doxx family
BFW76_RS06635	COG0667	Aldo Keto reductase
BFW76_RS06665	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BFW76_RS06685	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BFW76_RS06695	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BFW76_RS06730	COG0392	lysyltransferase activity
BFW76_RS06745	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BFW76_RS06750	COG3568	Endonuclease Exonuclease Phosphatase
BFW76_RS06760	COG1695	Transcriptional regulator
BFW76_RS06780	COG0583	DNA-binding transcription factor activity
BFW76_RS06795	COG1802	Transcriptional regulator
BFW76_RS06805	COG3181	Tripartite tricarboxylate transporter family receptor
BFW76_RS06815	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BFW76_RS06830	COG0066	3-isopropylmalate dehydratase activity
BFW76_RS06840	COG3181	Tripartite tricarboxylate transporter family receptor
BFW76_RS06845	COG4948	Mandelate Racemase Muconate Lactonizing
BFW76_RS06860	COG1126	abc transporter atp-binding protein
BFW76_RS06865	COG0765	amino acid transport
BFW76_RS06870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BFW76_RS06890	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BFW76_RS06915	COG1815	bacterial-type flagellum-dependent cell motility
BFW76_RS06920	COG1558	bacterial-type flagellum-dependent cell motility
BFW76_RS06930	COG1749	Flagellar hook protein flgE
BFW76_RS06945	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BFW76_RS06950	COG1706	bacterial-type flagellum-dependent cell motility
BFW76_RS06960	COG1256	bacterial-type flagellum assembly
BFW76_RS06970	COG0840	transmembrane signaling receptor activity
BFW76_RS06975	COG0840	transmembrane signaling receptor activity
BFW76_RS06980	COG0840	transmembrane signaling receptor activity
BFW76_RS07000	COG1338	Plays a role in the flagellum-specific transport system
BFW76_RS07020	COG1580	Controls the rotational direction of flagella during chemotaxis
BFW76_RS07045	COG1157	protein secretion by the type III secretion system
BFW76_RS07055	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BFW76_RS07065	COG1677	Flagellar hook-basal body complex protein FliE
BFW76_RS07075	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BFW76_RS07110	COG0285	dihydrofolate synthase activity
BFW76_RS07140	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BFW76_RS07145	COG0024	Methionine aminopeptidase
BFW76_RS07150	COG0052	Belongs to the universal ribosomal protein uS2 family
BFW76_RS07155	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BFW76_RS07160	COG0528	UMP kinase activity
BFW76_RS07165	COG0233	cytoplasmic translational termination
BFW76_RS07170	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BFW76_RS07180	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BFW76_RS07185	COG0750	zinc metalloprotease
BFW76_RS07190	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BFW76_RS07195	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
BFW76_RS07200	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BFW76_RS07205	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BFW76_RS07215	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BFW76_RS07220	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BFW76_RS07225	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BFW76_RS07230	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BFW76_RS07240	COG0519	Catalyzes the synthesis of GMP from XMP
BFW76_RS07240	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BFW76_RS07255	COG0330	HflC and HflK could
BFW76_RS07260	COG3706	GGDEF domain
BFW76_RS07265	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BFW76_RS07275	COG2867	negative regulation of translational initiation
BFW76_RS07285	COG1960	acyl-CoA dehydrogenase activity
BFW76_RS07290	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BFW76_RS07320	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BFW76_RS07325	COG0505	Belongs to the CarA family
BFW76_RS07330	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BFW76_RS07340	COG0406	alpha-ribazole phosphatase activity
BFW76_RS07350	COG3842	ATPase activity
BFW76_RS07370	COG5001	Diguanylate cyclase
BFW76_RS07375	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BFW76_RS07385	COG1763	Mo-molybdopterin cofactor biosynthetic process
BFW76_RS07390	COG0303	'Molybdopterin
BFW76_RS07395	COG0746	molybdenum cofactor guanylyltransferase activity
BFW76_RS07400	COG0489	protein tyrosine kinase activity
BFW76_RS07430	COG3383	formate dehydrogenase (NAD+) activity
BFW76_RS07430	COG0243	molybdopterin cofactor binding
BFW76_RS07435	COG0437	4 iron, 4 sulfur cluster binding
BFW76_RS07465	COG1122	ATPase activity
BFW76_RS07475	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BFW76_RS07480	COG0066	3-isopropylmalate dehydratase activity
BFW76_RS07485	COG0473	3-isopropylmalate dehydrogenase activity
BFW76_RS07490	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BFW76_RS07500	COG0101	tRNA pseudouridine synthase activity
BFW76_RS07505	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BFW76_RS07520	COG0135	phosphoribosylanthranilate isomerase activity
BFW76_RS07535	COG3022	response to hydroperoxide
BFW76_RS07545	COG1289	transmembrane transporter activity
BFW76_RS07550	COG3023	N-Acetylmuramoyl-L-alanine amidase
BFW76_RS07560	COG0424	maF-like protein
BFW76_RS07565	COG1399	metal-binding, possibly nucleic acid-binding protein
BFW76_RS07570	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BFW76_RS07575	COG0416	fatty acid biosynthetic process
BFW76_RS07580	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BFW76_RS07595	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BFW76_RS07600	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BFW76_RS07625	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BFW76_RS07630	COG0481	GTPase activity
BFW76_RS07635	COG0681	Belongs to the peptidase S26 family
BFW76_RS07640	COG0571	ribonuclease III activity
BFW76_RS07645	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BFW76_RS07650	COG1381	Involved in DNA repair and RecF pathway recombination
BFW76_RS07660	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BFW76_RS07675	COG3181	Tripartite tricarboxylate transporter family receptor
BFW76_RS07680	COG0670	Belongs to the BI1 family
BFW76_RS07695	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BFW76_RS07705	COG0583	DNA-binding transcription factor activity
BFW76_RS07720	COG0583	DNA-binding transcription factor activity
BFW76_RS07735	COG0791	NLP P60 protein
BFW76_RS07745	COG3193	protein, possibly involved in utilization of glycolate and propanediol
BFW76_RS07755	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BFW76_RS07760	COG0697	spore germination
BFW76_RS07765	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
BFW76_RS07780	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BFW76_RS07810	COG1446	asparaginase
BFW76_RS07815	COG4172	Belongs to the ABC transporter superfamily
BFW76_RS07820	COG0747	negative chemotaxis
BFW76_RS07830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BFW76_RS07855	COG0504	CTP synthase activity
BFW76_RS07860	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BFW76_RS07870	COG0148	phosphopyruvate hydratase activity
BFW76_RS07875	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BFW76_RS07905	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BFW76_RS07915	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BFW76_RS07940	COG1981	membrane
BFW76_RS07970	COG0039	L-malate dehydrogenase activity
BFW76_RS07975	COG2188	Transcriptional regulator
BFW76_RS07980	COG2009	succinate dehydrogenase
BFW76_RS07985	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BFW76_RS07990	COG1053	succinate dehydrogenase
BFW76_RS07995	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BFW76_RS08000	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BFW76_RS08005	COG0372	Belongs to the citrate synthase family
BFW76_RS08020	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BFW76_RS08020	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BFW76_RS08030	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BFW76_RS08035	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BFW76_RS08050	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BFW76_RS08055	COG3842	ATPase activity
BFW76_RS08060	COG1176	ABC-type spermidine putrescine transport system, permease component I
BFW76_RS08065	COG1177	transmembrane transport
BFW76_RS08090	COG1960	acyl-CoA dehydrogenase activity
BFW76_RS08095	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BFW76_RS08100	COG0704	Plays a role in the regulation of phosphate uptake
BFW76_RS08110	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
BFW76_RS08115	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BFW76_RS08115	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BFW76_RS08120	COG1643	Atp-dependent helicase
BFW76_RS08135	COG0438	transferase activity, transferring glycosyl groups
BFW76_RS08140	COG0726	polysaccharide deacetylase
BFW76_RS08145	COG0463	Glycosyl transferase, family 2
BFW76_RS08150	COG0438	transferase activity, transferring glycosyl groups
BFW76_RS08155	COG2194	sulfuric ester hydrolase activity
BFW76_RS08180	COG0859	PFAM glycosyl transferase family 9
BFW76_RS08185	COG1132	(ABC) transporter
BFW76_RS08200	COG0077	Prephenate dehydratase
BFW76_RS08205	COG1530	ribonuclease E activity
BFW76_RS08245	COG3468	outer membrane autotransporter barrel domain protein
BFW76_RS08250	COG0424	maF-like protein
BFW76_RS08255	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BFW76_RS08260	COG0799	negative regulation of ribosome biogenesis
BFW76_RS08265	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BFW76_RS08270	COG0408	coproporphyrinogen oxidase activity
BFW76_RS08275	COG0151	Belongs to the GarS family
BFW76_RS08280	COG0217	transcriptional regulatory protein
BFW76_RS08285	COG0433	COG0433 Predicted ATPase
BFW76_RS08290	COG1115	amino acid carrier protein
BFW76_RS08295	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BFW76_RS08305	COG1012	belongs to the aldehyde dehydrogenase family
BFW76_RS08330	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BFW76_RS08345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BFW76_RS08355	COG0747	negative chemotaxis
BFW76_RS08365	COG0473	3-isopropylmalate dehydrogenase activity
BFW76_RS08370	COG2814	Major facilitator Superfamily
BFW76_RS08375	COG1566	PFAM secretion protein HlyD family protein
BFW76_RS08385	COG1846	Transcriptional regulator
BFW76_RS08395	COG0697	spore germination
BFW76_RS08405	COG0501	Belongs to the peptidase M48B family
BFW76_RS08425	COG0583	DNA-binding transcription factor activity
BFW76_RS08430	COG3842	ATPase activity
BFW76_RS08435	COG1178	ABC-type Fe3 transport system permease component
BFW76_RS08440	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BFW76_RS08445	COG1840	ABC-type Fe3 transport system, periplasmic component
BFW76_RS08450	COG0492	ferredoxin-NADP+ reductase activity
BFW76_RS08470	COG2233	PERMEase
BFW76_RS08475	COG0840	transmembrane signaling receptor activity
BFW76_RS08480	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BFW76_RS08510	COG4789	Type iii secretion
BFW76_RS08575	COG4669	(LipO)protein
BFW76_RS08610	COG4790	Type iii secretion
BFW76_RS08615	COG4794	Type iii secretion
BFW76_RS08620	COG4791	protein targeting
BFW76_RS08625	COG4792	protein secretion
BFW76_RS08640	COG1595	DNA-templated transcription, initiation
BFW76_RS08660	COG2770	Histidine kinase
BFW76_RS08660	COG2208	phosphoserine phosphatase activity
BFW76_RS08670	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BFW76_RS08675	COG2172	sigma factor antagonist activity
BFW76_RS08680	COG1366	Belongs to the anti-sigma-factor antagonist family
BFW76_RS08685	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BFW76_RS08715	COG2358	TRAP transporter, solute receptor (TAXI family
BFW76_RS08720	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BFW76_RS08750	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BFW76_RS08760	COG2252	PERMEase
BFW76_RS08765	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BFW76_RS08775	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BFW76_RS08780	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BFW76_RS08810	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BFW76_RS08815	COG0789	Transcriptional regulator
BFW76_RS08825	COG0678	peroxiredoxin activity
BFW76_RS08825	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BFW76_RS08835	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BFW76_RS08840	COG0584	glycerophosphoryl diester phosphodiesterase
BFW76_RS08845	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BFW76_RS08855	COG4181	ATPase activity
BFW76_RS08875	COG2823	Periplasmic or secreted lipoprotein
BFW76_RS08885	COG3237	CsbD-like
BFW76_RS08890	COG1181	Belongs to the D-alanine--D-alanine ligase family
BFW76_RS08890	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BFW76_RS08895	COG0189	ligase activity
BFW76_RS08895	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BFW76_RS08915	COG2833	Protein of unknown function (DUF455)
BFW76_RS08920	COG2951	lytic endotransglycosylase activity
BFW76_RS08940	COG1522	sequence-specific DNA binding
BFW76_RS08950	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BFW76_RS08955	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BFW76_RS08960	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BFW76_RS08965	COG0196	riboflavin kinase activity
BFW76_RS08970	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BFW76_RS08990	COG0210	DNA helicase
BFW76_RS08995	COG4771	TonB-dependent receptor
BFW76_RS09000	COG0488	(ABC) transporter
BFW76_RS09005	COG2890	protein-(glutamine-N5) methyltransferase activity
BFW76_RS09010	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BFW76_RS09015	COG2171	N-acyltransferase activity
BFW76_RS09050	COG1278	Cold shock
BFW76_RS09070	COG0544	peptidyl-prolyl cis-trans isomerase activity
BFW76_RS09075	COG0740	serine-type endopeptidase activity
BFW76_RS09080	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BFW76_RS09085	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BFW76_RS09090	COG0583	DNA-binding transcription factor activity
BFW76_RS09095	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BFW76_RS09110	COG1024	Enoyl-CoA hydratase
BFW76_RS09120	COG0183	Belongs to the thiolase family
BFW76_RS09125	COG1028	Short-chain dehydrogenase reductase Sdr
BFW76_RS09130	COG1960	acyl-CoA dehydrogenase activity
BFW76_RS09145	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BFW76_RS09170	COG3468	outer membrane autotransporter barrel domain protein
BFW76_RS09175	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BFW76_RS09185	COG0556	nucleotide-excision repair
BFW76_RS09190	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BFW76_RS09200	COG1104	cysteine desulfurase activity
BFW76_RS09205	COG0822	iron-sulfur transferase activity
BFW76_RS09210	COG0316	Belongs to the HesB IscA family
BFW76_RS09215	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BFW76_RS09220	COG0443	Heat shock 70 kDa protein
BFW76_RS09225	COG0633	Ferredoxin
BFW76_RS09245	COG1024	Enoyl-CoA hydratase
BFW76_RS09260	COG3395	kinase activity
BFW76_RS09265	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BFW76_RS09280	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BFW76_RS09290	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BFW76_RS09315	COG0747	negative chemotaxis
BFW76_RS09320	COG0601	transmembrane transport
BFW76_RS09325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BFW76_RS09330	COG4172	Belongs to the ABC transporter superfamily
BFW76_RS09335	COG0154	amidase activity
BFW76_RS09380	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BFW76_RS09385	COG0425	Belongs to the sulfur carrier protein TusA family
BFW76_RS09395	COG0228	four-way junction DNA binding
BFW76_RS09400	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BFW76_RS09405	COG0336	Belongs to the RNA methyltransferase TrmD family
BFW76_RS09410	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BFW76_RS09435	COG0642	Histidine kinase
BFW76_RS09450	COG0525	valine-tRNA ligase activity
BFW76_RS09455	COG0105	UTP biosynthetic process
BFW76_RS09460	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BFW76_RS09470	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BFW76_RS09475	COG0124	histidyl-tRNA synthetase
BFW76_RS09480	COG2976	Protein conserved in bacteria
BFW76_RS09485	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BFW76_RS09490	COG1160	GTP binding
BFW76_RS09495	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BFW76_RS09500	COG1923	regulation of RNA biosynthetic process
BFW76_RS09505	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BFW76_RS09510	COG0330	HflC and HflK could
BFW76_RS09515	COG0330	HflC and HflK could
BFW76_RS09520	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BFW76_RS09525	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BFW76_RS09530	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BFW76_RS09535	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BFW76_RS09545	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BFW76_RS09580	COG0628	permease
BFW76_RS09585	COG0842	Transport permease protein
BFW76_RS09590	COG1131	(ABC) transporter
BFW76_RS09660	COG0156	8-amino-7-oxononanoate synthase activity
BFW76_RS09670	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BFW76_RS09670	COG4106	trans-aconitate 2-methyltransferase activity
BFW76_RS09675	COG1380	Effector of murein hydrolase LrgA
BFW76_RS09690	COG3284	Transcriptional regulator
BFW76_RS09695	COG1012	belongs to the aldehyde dehydrogenase family
BFW76_RS09710	COG2733	membrane
BFW76_RS09715	COG0583	DNA-binding transcription factor activity
BFW76_RS09720	COG0384	phenazine biosynthesis protein PhzF
BFW76_RS09725	COG5507	3-demethylubiquinone-9 3-methyltransferase
BFW76_RS09730	COG2169	Transcriptional regulator
BFW76_RS09760	COG0659	secondary active sulfate transmembrane transporter activity
BFW76_RS09785	COG1132	(ABC) transporter
BFW76_RS09835	COG2207	Transcriptional regulator
BFW76_RS09975	COG2346	COG2346, Truncated hemoglobins
BFW76_RS10020	COG0183	Belongs to the thiolase family
BFW76_RS10035	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BFW76_RS10040	COG0633	Ferredoxin
BFW76_RS10050	COG1024	Enoyl-CoA hydratase
BFW76_RS10060	COG4638	Rieske (2fe-2S)
BFW76_RS10070	COG0559	Belongs to the binding-protein-dependent transport system permease family
BFW76_RS10090	COG2224	Isocitrate lyase
BFW76_RS10095	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BFW76_RS10095	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BFW76_RS10105	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BFW76_RS10110	COG0322	excinuclease ABC activity
BFW76_RS10115	COG1472	Belongs to the glycosyl hydrolase 3 family
BFW76_RS10120	COG0736	holo-[acyl-carrier-protein] synthase activity
BFW76_RS10125	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BFW76_RS10135	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BFW76_RS10140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BFW76_RS10165	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BFW76_RS10180	COG2032	superoxide dismutase activity
BFW76_RS10195	COG1024	Enoyl-CoA hydratase
BFW76_RS10205	COG1802	Transcriptional regulator
BFW76_RS10215	COG0183	Belongs to the thiolase family
BFW76_RS10220	COG1942	4-Oxalocrotonate Tautomerase
BFW76_RS10230	COG4176	ABC-type proline glycine betaine transport system permease component
BFW76_RS10245	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BFW76_RS10250	COG2814	Major facilitator Superfamily
BFW76_RS10255	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BFW76_RS10260	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BFW76_RS10290	COG2814	Major facilitator Superfamily
BFW76_RS10295	COG0495	leucyl-tRNA aminoacylation
BFW76_RS10310	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BFW76_RS10320	COG0154	amidase activity
BFW76_RS10325	COG1250	3-hydroxyacyl-CoA dehydrogenase
BFW76_RS10380	COG0427	acetyl-CoA hydrolase
BFW76_RS10385	COG0583	DNA-binding transcription factor activity
BFW76_RS10405	COG0730	response to heat
BFW76_RS10410	COG0697	spore germination
BFW76_RS10445	COG2885	chlorophyll binding
BFW76_RS10470	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BFW76_RS10475	COG3384	dioxygenase
BFW76_RS10490	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BFW76_RS10495	COG3474	cytochrome
BFW76_RS10505	COG1595	DNA-templated transcription, initiation
BFW76_RS10520	COG2204	response regulator
BFW76_RS10560	COG4964	Belongs to the GSP D family
BFW76_RS10610	COG1846	Transcriptional regulator
BFW76_RS10615	COG4172	Belongs to the ABC transporter superfamily
BFW76_RS10620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BFW76_RS10625	COG0601	transmembrane transport
BFW76_RS10630	COG0747	negative chemotaxis
BFW76_RS10640	COG0598	Magnesium transport protein CorA
BFW76_RS10645	COG0210	DNA helicase
BFW76_RS10660	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BFW76_RS10665	COG1012	belongs to the aldehyde dehydrogenase family
BFW76_RS10670	COG0483	inositol monophosphate 1-phosphatase activity
BFW76_RS10675	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BFW76_RS10685	COG1045	serine acetyltransferase
BFW76_RS10690	COG0166	Belongs to the GPI family
BFW76_RS10705	COG2197	response regulator
BFW76_RS10710	COG1846	Transcriptional regulator
BFW76_RS10730	COG0726	polysaccharide deacetylase
BFW76_RS10730	COG1649	PFAM Uncharacterised BCR, COG1649
BFW76_RS10735	COG1215	transferase activity, transferring glycosyl groups
BFW76_RS10745	COG1902	pentaerythritol trinitrate reductase activity
BFW76_RS10770	COG0251	oxidation-reduction process
BFW76_RS10780	COG1832	CoA-binding protein
BFW76_RS10785	COG1414	Transcriptional regulator
BFW76_RS10790	COG0446	pyridine nucleotide-disulphide oxidoreductase
BFW76_RS10790	COG1902	pentaerythritol trinitrate reductase activity
BFW76_RS10800	COG3842	ATPase activity
BFW76_RS10825	COG0583	DNA-binding transcription factor activity
BFW76_RS10835	COG1028	Short-chain dehydrogenase reductase Sdr
BFW76_RS10840	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
BFW76_RS10845	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BFW76_RS10860	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BFW76_RS10860	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BFW76_RS10865	COG1250	3-hydroxyacyl-CoA dehydrogenase
BFW76_RS10890	COG0527	aspartate kinase activity
BFW76_RS10895	COG0037	tRNA processing
BFW76_RS10905	COG0825	malonyl-CoA metabolic process
BFW76_RS10915	COG0215	cysteine-tRNA ligase activity
BFW76_RS10930	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BFW76_RS10935	COG1968	undecaprenyl-diphosphatase activity
BFW76_RS10940	COG1253	flavin adenine dinucleotide binding
BFW76_RS10945	COG0483	inositol monophosphate 1-phosphatase activity
BFW76_RS10965	COG0668	transmembrane transport
BFW76_RS10990	COG0583	DNA-binding transcription factor activity
BFW76_RS11015	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BFW76_RS11030	COG2831	hemolysin activation secretion protein
BFW76_RS11035	COG3539	Fimbrial protein
BFW76_RS11040	COG3188	usher protein
BFW76_RS11045	COG3121	Chaperone
BFW76_RS11055	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
BFW76_RS11055	COG3064	Membrane
BFW76_RS11055	COG3210	domain, Protein
BFW76_RS11060	COG2197	response regulator
BFW76_RS11065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BFW76_RS11065	COG2205	protein histidine kinase activity
BFW76_RS11075	COG4336	lyase activity
BFW76_RS11100	COG2010	Cytochrome c
BFW76_RS11105	COG3189	MarR family transcriptional regulator
BFW76_RS11125	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BFW76_RS11135	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BFW76_RS11135	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BFW76_RS11145	COG0028	Belongs to the TPP enzyme family
BFW76_RS11155	COG1012	belongs to the aldehyde dehydrogenase family
BFW76_RS11160	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BFW76_RS11165	COG0010	Belongs to the arginase family
BFW76_RS11170	COG1126	abc transporter atp-binding protein
BFW76_RS11180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BFW76_RS11195	COG0084	hydrolase, TatD family'
BFW76_RS11200	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BFW76_RS11205	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BFW76_RS11210	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BFW76_RS11230	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BFW76_RS11235	COG1959	2 iron, 2 sulfur cluster binding
BFW76_RS11240	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BFW76_RS11240	COG1017	nitric oxide dioxygenase activity
BFW76_RS11275	COG0488	(ABC) transporter
BFW76_RS11280	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BFW76_RS11295	COG1024	Enoyl-CoA hydratase
BFW76_RS11300	COG1619	proteins homologs of microcin C7 resistance protein MccF
BFW76_RS11305	COG0590	tRNA wobble adenosine to inosine editing
BFW76_RS11330	COG2212	antiporter activity
BFW76_RS11335	COG1863	multisubunit Na H antiporter MnhE subunit
BFW76_RS11340	COG0651	ATP synthesis coupled electron transport
BFW76_RS11345	COG1006	Multisubunit Na H antiporter MnhC subunit
BFW76_RS11350	COG2111	Na H antiporter
BFW76_RS11350	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BFW76_RS11355	COG3181	Tripartite tricarboxylate transporter family receptor
BFW76_RS11370	COG0583	DNA-binding transcription factor activity
BFW76_RS11375	COG1028	Short-chain dehydrogenase reductase Sdr
BFW76_RS11405	COG0431	NADPH-dependent FMN reductase
BFW76_RS11450	COG1028	Short-chain dehydrogenase reductase Sdr
BFW76_RS11455	COG0179	Fumarylacetoacetate (FAA) hydrolase
BFW76_RS11485	COG0625	glutathione transferase activity
BFW76_RS11490	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
BFW76_RS11495	COG2944	sequence-specific DNA binding
BFW76_RS11505	COG2197	response regulator
BFW76_RS11530	COG3119	arylsulfatase activity
BFW76_RS11565	COG0714	Associated with various cellular activities
BFW76_RS11585	COG1028	Short-chain dehydrogenase reductase Sdr
BFW76_RS11590	COG0861	Integral membrane protein TerC family
BFW76_RS11635	COG0300	oxidoreductase activity
BFW76_RS11660	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BFW76_RS11675	COG0438	transferase activity, transferring glycosyl groups
BFW76_RS11695	COG0463	Glycosyl transferase, family 2
BFW76_RS11710	COG0783	Belongs to the Dps family
BFW76_RS11725	COG0583	DNA-binding transcription factor activity
BFW76_RS11730	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BFW76_RS11745	COG0656	L-ascorbic acid biosynthetic process
BFW76_RS11755	COG0583	DNA-binding transcription factor activity
BFW76_RS11765	COG1840	ABC-type Fe3 transport system, periplasmic component
BFW76_RS11770	COG1178	ABC-type Fe3 transport system permease component
BFW76_RS11775	COG3842	ATPase activity
BFW76_RS11785	COG1741	Belongs to the pirin family
BFW76_RS11790	COG1741	Belongs to the pirin family
BFW76_RS11795	COG0583	DNA-binding transcription factor activity
BFW76_RS11800	COG2204	response regulator
BFW76_RS11810	COG0174	glutamine synthetase
BFW76_RS11815	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BFW76_RS11825	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BFW76_RS11830	COG2200	EAL domain
BFW76_RS11830	COG2199	diguanylate cyclase activity
BFW76_RS11835	COG0840	transmembrane signaling receptor activity
BFW76_RS11850	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BFW76_RS11855	COG1561	YicC-like family, N-terminal region
BFW76_RS11875	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BFW76_RS11880	COG0791	NLP P60 protein
BFW76_RS11885	COG1028	Short-chain dehydrogenase reductase Sdr
BFW76_RS11890	COG2863	cytochrome
BFW76_RS11895	COG3258	Cytochrome c
BFW76_RS11900	COG0194	GDP metabolic process
BFW76_RS11905	COG1758	RNA polymerase activity
BFW76_RS11910	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BFW76_RS11915	COG1126	abc transporter atp-binding protein
BFW76_RS11920	COG0765	amino acid transport
BFW76_RS11925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BFW76_RS11935	COG1994	Peptidase M50
BFW76_RS11940	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BFW76_RS11945	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BFW76_RS11950	COG3539	Fimbrial protein
BFW76_RS11955	COG2850	peptidyl-arginine hydroxylation
BFW76_RS11960	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BFW76_RS11965	COG3360	Dodecin
BFW76_RS12010	COG0009	L-threonylcarbamoyladenylate synthase
BFW76_RS12015	COG2321	neutral zinc metallopeptidase
BFW76_RS12035	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BFW76_RS12040	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BFW76_RS12045	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BFW76_RS12055	COG1074	ATP-dependent DNA helicase activity
BFW76_RS12065	COG2814	Major facilitator Superfamily
BFW76_RS12075	COG1686	Belongs to the peptidase S11 family
BFW76_RS12090	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BFW76_RS12095	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BFW76_RS12100	COG4974	Belongs to the 'phage' integrase family
BFW76_RS12105	COG0583	DNA-binding transcription factor activity
BFW76_RS12110	COG0028	Belongs to the TPP enzyme family
BFW76_RS12125	COG0028	Belongs to the TPP enzyme family
BFW76_RS12130	COG1126	abc transporter atp-binding protein
BFW76_RS12135	COG0765	amino acid transport
BFW76_RS12150	COG1414	Transcriptional regulator
BFW76_RS12155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BFW76_RS12160	COG0009	L-threonylcarbamoyladenylate synthase
BFW76_RS12165	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BFW76_RS12170	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BFW76_RS12175	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BFW76_RS12185	COG2944	sequence-specific DNA binding
BFW76_RS12195	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BFW76_RS12250	COG1126	abc transporter atp-binding protein
BFW76_RS12255	COG0765	amino acid transport
BFW76_RS12260	COG0765	amino acid transport
BFW76_RS12265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BFW76_RS12275	COG2423	ornithine cyclodeaminase activity
BFW76_RS12280	COG1764	response to oxidative stress
BFW76_RS12290	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BFW76_RS12295	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BFW76_RS12305	COG0189	ligase activity
BFW76_RS12310	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BFW76_RS12315	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BFW76_RS12320	COG2197	response regulator
BFW76_RS12330	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BFW76_RS12350	COG1289	transmembrane transporter activity
BFW76_RS12360	COG3022	response to hydroperoxide
BFW76_RS12370	COG1028	Short-chain dehydrogenase reductase Sdr
BFW76_RS12385	COG3486	L-lysine 6-monooxygenase (NADPH) activity
BFW76_RS12415	COG2814	Major facilitator Superfamily
BFW76_RS12435	COG3706	GGDEF domain
BFW76_RS12460	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BFW76_RS12465	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BFW76_RS12470	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BFW76_RS12475	COG1674	ftsk spoiiie
BFW76_RS12480	COG0492	ferredoxin-NADP+ reductase activity
BFW76_RS12485	COG1193	negative regulation of DNA recombination
BFW76_RS12505	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BFW76_RS12520	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BFW76_RS12525	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BFW76_RS12530	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
BFW76_RS12540	COG0745	RESPONSE REGULATOR receiver
BFW76_RS12585	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BFW76_RS12605	COG0612	Peptidase, M16
BFW76_RS12615	COG0443	Heat shock 70 kDa protein
BFW76_RS12625	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BFW76_RS12635	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BFW76_RS12640	COG1420	regulation of RNA biosynthetic process
BFW76_RS12645	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BFW76_RS12650	COG0497	DNA recombination
BFW76_RS12655	COG0735	belongs to the Fur family
BFW76_RS12660	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BFW76_RS12665	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BFW76_RS12670	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BFW76_RS12705	COG0446	pyridine nucleotide-disulphide oxidoreductase
BFW76_RS12705	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BFW76_RS12710	COG4311	Sarcosine oxidase, delta subunit
BFW76_RS12715	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BFW76_RS12725	COG0583	DNA-binding transcription factor activity
BFW76_RS12735	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BFW76_RS12760	COG4964	Belongs to the GSP D family
BFW76_RS12820	COG0181	hydroxymethylbilane synthase activity
BFW76_RS12825	COG0861	Integral membrane protein TerC family
BFW76_RS12830	COG0861	Integral membrane protein TerC family
BFW76_RS12835	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BFW76_RS12840	COG0045	succinate-CoA ligase (ADP-forming) activity
BFW76_RS12850	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BFW76_RS12860	COG2137	regulation of response to DNA damage stimulus
BFW76_RS12865	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BFW76_RS12885	COG1250	3-hydroxyacyl-CoA dehydrogenase
BFW76_RS12885	COG1024	Enoyl-CoA hydratase
BFW76_RS12890	COG3842	ATPase activity
BFW76_RS12905	COG1028	Short-chain dehydrogenase reductase Sdr
BFW76_RS12925	COG0583	DNA-binding transcription factor activity
BFW76_RS12930	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BFW76_RS12940	COG2974	May be involved in recombination
BFW76_RS12945	COG0540	Belongs to the ATCase OTCase family
BFW76_RS13015	COG0776	regulation of translation
BFW76_RS13020	COG0072	phenylalanine-tRNA ligase activity
BFW76_RS13020	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BFW76_RS13025	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BFW76_RS13030	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BFW76_RS13035	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BFW76_RS13050	COG0756	dUTP diphosphatase activity
BFW76_RS13060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BFW76_RS13075	COG0500	methyltransferase
BFW76_RS13090	COG0586	Pfam SNARE associated Golgi protein
BFW76_RS13120	COG1609	Transcriptional regulator
BFW76_RS13125	COG4172	Belongs to the ABC transporter superfamily
BFW76_RS13130	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BFW76_RS13135	COG0601	transmembrane transport
BFW76_RS13140	COG0747	negative chemotaxis
BFW76_RS13155	COG1280	lysine exporter protein (LysE YggA)
BFW76_RS13170	COG2814	Major facilitator Superfamily
BFW76_RS13200	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BFW76_RS13220	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BFW76_RS13255	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BFW76_RS13260	COG1116	anion transmembrane transporter activity
BFW76_RS13270	COG1228	amidohydrolase
BFW76_RS13285	COG0477	Major facilitator Superfamily
BFW76_RS13295	COG3550	peptidyl-serine autophosphorylation
BFW76_RS13310	COG0519	Catalyzes the synthesis of GMP from XMP
BFW76_RS13310	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BFW76_RS13350	COG0420	3'-5' exonuclease activity
BFW76_RS13355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BFW76_RS13385	COG0395	ABC-type sugar transport system, permease component
BFW76_RS13395	COG3842	ATPase activity
BFW76_RS13420	COG3181	Tripartite tricarboxylate transporter family receptor
BFW76_RS13455	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BFW76_RS13480	COG0602	queuosine metabolic process
BFW76_RS13485	COG0720	synthase
BFW76_RS13490	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BFW76_RS13495	COG0235	Class ii aldolase
BFW76_RS13525	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
BFW76_RS13525	COG3064	Membrane
BFW76_RS13525	COG3210	domain, Protein
BFW76_RS13530	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BFW76_RS13530	COG0047	phosphoribosylformylglycinamidine synthase activity
BFW76_RS13535	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BFW76_RS13540	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BFW76_RS13540	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BFW76_RS13545	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BFW76_RS13565	COG3539	Fimbrial protein
BFW76_RS13575	COG2050	protein possibly involved in aromatic compounds catabolism
BFW76_RS13580	COG1024	Enoyl-CoA hydratase
BFW76_RS13585	COG1012	belongs to the aldehyde dehydrogenase family
BFW76_RS13600	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BFW76_RS13605	COG2151	metal-sulfur cluster biosynthetic enzyme
BFW76_RS13610	COG3396	Phenylacetate-CoA oxygenase
BFW76_RS13615	COG3460	Phenylacetate-CoA oxygenase
BFW76_RS13620	COG3396	Phenylacetate-CoA oxygenase
BFW76_RS13625	COG3327	negative regulation of DNA-templated transcription, initiation
BFW76_RS13635	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BFW76_RS13640	COG0501	Belongs to the peptidase M48B family
BFW76_RS13645	COG1162	GTPase activity
BFW76_RS13655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BFW76_RS13660	COG0601	transmembrane transport
BFW76_RS13665	COG0747	negative chemotaxis
BFW76_RS13710	COG0668	transmembrane transport
BFW76_RS13715	COG0165	Argininosuccinate lyase
BFW76_RS13735	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BFW76_RS13740	COG0303	'Molybdopterin
BFW76_RS13745	COG0521	Mo-molybdopterin cofactor biosynthetic process
BFW76_RS13760	COG0315	cyclic pyranopterin monophosphate synthase activity
BFW76_RS13770	COG0412	Dienelactone hydrolase
BFW76_RS13780	COG0678	peroxiredoxin activity
BFW76_RS13790	COG0697	spore germination
BFW76_RS13795	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BFW76_RS13820	COG0789	Transcriptional regulator
BFW76_RS13835	COG1028	Short-chain dehydrogenase reductase Sdr
BFW76_RS13845	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BFW76_RS13850	COG1845	cytochrome c oxidase, subunit III
BFW76_RS13855	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BFW76_RS13865	COG0477	Major facilitator Superfamily
BFW76_RS13900	COG1309	transcriptional regulator
BFW76_RS13905	COG2271	Major facilitator Superfamily
BFW76_RS13940	COG0506	proline dehydrogenase activity
BFW76_RS13940	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BFW76_RS13940	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BFW76_RS13950	COG3008	intermembrane lipid transfer
BFW76_RS13950	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BFW76_RS13955	COG2995	paraquat-inducible protein a
BFW76_RS13960	COG0542	response to heat
BFW76_RS13965	COG4953	penicillin-binding protein 1C
BFW76_RS13975	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BFW76_RS13980	COG1278	Cold shock
BFW76_RS13990	COG0183	Belongs to the thiolase family
BFW76_RS13995	COG0038	chloride channel
BFW76_RS14000	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BFW76_RS14005	COG1570	exodeoxyribonuclease VII activity
BFW76_RS14015	COG0811	peptide transport
BFW76_RS14020	COG0848	biopolymer transport protein
BFW76_RS14025	COG1663	tetraacyldisaccharide 4'-kinase activity
BFW76_RS14030	COG2835	tetraacyldisaccharide 4'-kinase activity
BFW76_RS14035	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BFW76_RS14040	COG0563	adenylate kinase activity
BFW76_RS14050	COG0728	peptidoglycan biosynthetic process
BFW76_RS14060	COG0268	Binds directly to 16S ribosomal RNA
BFW76_RS14095	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BFW76_RS14120	COG0436	Aminotransferase
BFW76_RS14125	COG3737	Protein of unknown function (DUF498/DUF598)
BFW76_RS14130	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BFW76_RS14135	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BFW76_RS14140	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BFW76_RS14150	COG0305	Participates in initiation and elongation during chromosome replication
BFW76_RS14160	COG0359	binds to the 23S rRNA
BFW76_RS14165	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BFW76_RS14170	COG2965	DNA replication, synthesis of RNA primer
BFW76_RS14175	COG0360	Binds together with S18 to 16S ribosomal RNA
BFW76_RS14180	COG1469	GTP cyclohydrolase I activity
BFW76_RS14185	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BFW76_RS14190	COG0142	geranyltranstransferase activity
BFW76_RS14195	COG1722	exodeoxyribonuclease VII activity
BFW76_RS14205	COG3181	Tripartite tricarboxylate transporter family receptor
BFW76_RS14225	COG2239	Acts as a magnesium transporter
BFW76_RS14235	COG2855	membrane
BFW76_RS14245	COG1473	amidohydrolase
BFW76_RS14250	COG0318	PFAM AMP-dependent synthetase and ligase
BFW76_RS14275	COG1501	Belongs to the glycosyl hydrolase 31 family
BFW76_RS14280	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BFW76_RS14285	COG2011	ABC-type metal ion transport system permease component
BFW76_RS14305	COG1454	alcohol dehydrogenase
BFW76_RS14335	COG2186	Transcriptional regulator
BFW76_RS14340	COG3181	Tripartite tricarboxylate transporter family receptor
BFW76_RS14360	COG1175	transmembrane transport
BFW76_RS14365	COG0395	ABC-type sugar transport system, permease component
BFW76_RS14370	COG3842	ATPase activity
BFW76_RS14375	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BFW76_RS14385	COG1653	transport
BFW76_RS14405	COG2818	Glycosylase
BFW76_RS14410	COG2982	Protein involved in outer membrane biogenesis
BFW76_RS14420	COG1309	transcriptional regulator
BFW76_RS14425	COG1028	Short-chain dehydrogenase reductase Sdr
BFW76_RS14485	COG0583	DNA-binding transcription factor activity
BFW76_RS14490	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BFW76_RS14495	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BFW76_RS14510	COG1028	Short-chain dehydrogenase reductase Sdr
BFW76_RS14515	COG0477	Major facilitator Superfamily
BFW76_RS14525	COG0583	DNA-binding transcription factor activity
BFW76_RS14530	COG1448	Aminotransferase
BFW76_RS14535	COG1418	mRNA catabolic process
BFW76_RS14560	COG1063	alcohol dehydrogenase
BFW76_RS14580	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BFW76_RS14590	COG0318	PFAM AMP-dependent synthetase and ligase
BFW76_RS14600	COG1522	sequence-specific DNA binding
BFW76_RS14605	COG3181	Tripartite tricarboxylate transporter family receptor
BFW76_RS14610	COG0307	riboflavin synthase, alpha
BFW76_RS14615	COG0154	amidase activity
BFW76_RS14625	COG3181	Tripartite tricarboxylate transporter family receptor
BFW76_RS14635	COG2807	transmembrane transport
BFW76_RS14640	COG0590	tRNA wobble adenosine to inosine editing
BFW76_RS14650	COG0583	DNA-binding transcription factor activity
BFW76_RS14665	COG1902	pentaerythritol trinitrate reductase activity
BFW76_RS14685	COG0559	Belongs to the binding-protein-dependent transport system permease family
BFW76_RS14690	COG0251	oxidation-reduction process
BFW76_RS14695	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BFW76_RS14705	COG1414	Transcriptional regulator
BFW76_RS14710	COG1028	Short-chain dehydrogenase reductase Sdr
BFW76_RS14725	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BFW76_RS14740	COG1024	Enoyl-CoA hydratase
BFW76_RS14745	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BFW76_RS14750	COG0154	amidase activity
BFW76_RS14790	COG3909	cytochrome
BFW76_RS14795	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BFW76_RS14800	COG0625	glutathione transferase activity
BFW76_RS14805	COG0730	response to heat
BFW76_RS14810	COG0482	sulfurtransferase activity
BFW76_RS14815	COG0583	DNA-binding transcription factor activity
BFW76_RS14835	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BFW76_RS14855	COG2819	hydrolase of the alpha beta superfamily
BFW76_RS14860	COG0247	lactate metabolic process
BFW76_RS14865	COG0277	FAD linked oxidase domain protein
BFW76_RS14870	COG0277	FAD linked oxidase domain protein
BFW76_RS14875	COG0277	FAD linked oxidase domain protein
BFW76_RS14880	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
BFW76_RS14880	COG3210	domain, Protein
BFW76_RS14880	COG3064	Membrane
BFW76_RS14880	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
BFW76_RS14880	COG3210	domain, Protein
BFW76_RS14880	COG3064	Membrane
BFW76_RS14885	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BFW76_RS14890	COG0312	modulator of DNA gyrase
BFW76_RS14925	COG1666	GTP binding
BFW76_RS14970	COG3220	belongs to the UPF0276 family
BFW76_RS14990	COG0640	Transcriptional regulator
BFW76_RS14995	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BFW76_RS15000	COG1845	cytochrome c oxidase, subunit III
BFW76_RS15005	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BFW76_RS15015	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BFW76_RS15050	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BFW76_RS15055	COG0583	DNA-binding transcription factor activity
BFW76_RS15090	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BFW76_RS15090	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BFW76_RS15105	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BFW76_RS15110	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BFW76_RS15120	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BFW76_RS15135	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BFW76_RS15140	COG0316	Belongs to the HesB IscA family
BFW76_RS15150	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BFW76_RS15155	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BFW76_RS15160	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BFW76_RS15165	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BFW76_RS15170	COG0312	modulator of DNA gyrase
BFW76_RS15175	COG3028	Belongs to the UPF0307 family
BFW76_RS15190	COG1116	anion transmembrane transporter activity
BFW76_RS15195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BFW76_RS15200	COG1335	isochorismatase
BFW76_RS15205	COG0346	lactoylglutathione lyase activity
BFW76_RS15210	COG0513	Belongs to the DEAD box helicase family
BFW76_RS15215	COG3069	C4-dicarboxylate transmembrane transporter activity
BFW76_RS15220	COG1802	Transcriptional regulator
BFW76_RS15235	COG0045	succinate-CoA ligase (ADP-forming) activity
BFW76_RS15235	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BFW76_RS15235	COG1042	CoA-binding domain protein
BFW76_RS15240	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BFW76_RS15255	COG1522	sequence-specific DNA binding
BFW76_RS15290	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BFW76_RS15295	COG1696	Membrane protein involved in D-alanine export
BFW76_RS15320	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BFW76_RS15330	COG2264	protein methyltransferase activity
BFW76_RS15335	COG0439	Biotin carboxylase
BFW76_RS15340	COG0511	ligase activity, forming carbon-carbon bonds
BFW76_RS15345	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BFW76_RS15350	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BFW76_RS15355	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BFW76_RS15360	COG3150	esterase
BFW76_RS15365	COG0557	exoribonuclease II activity
BFW76_RS15375	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BFW76_RS15395	COG1522	sequence-specific DNA binding
BFW76_RS15400	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BFW76_RS15405	COG1028	Short-chain dehydrogenase reductase Sdr
BFW76_RS15425	COG0653	protein targeting
BFW76_RS15430	COG0739	heme binding
BFW76_RS15440	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BFW76_RS15445	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BFW76_RS15455	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BFW76_RS15460	COG1181	Belongs to the D-alanine--D-alanine ligase family
BFW76_RS15465	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BFW76_RS15470	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BFW76_RS15480	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BFW76_RS15485	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BFW76_RS15490	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BFW76_RS15500	COG3116	cell division
BFW76_RS15505	COG0275	rRNA processing
BFW76_RS15510	COG2001	Belongs to the MraZ family
BFW76_RS15520	COG0488	(ABC) transporter
BFW76_RS15525	COG0418	dihydroorotase activity
BFW76_RS15530	COG1473	amidohydrolase
BFW76_RS15580	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BFW76_RS15585	COG4654	Cytochrome c, class I
BFW76_RS15590	COG0129	dihydroxy-acid dehydratase activity
BFW76_RS15595	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BFW76_RS15645	COG2084	Dehydrogenase
BFW76_RS15650	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BFW76_RS15665	COG2096	Adenosyltransferase
BFW76_RS15680	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BFW76_RS15685	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BFW76_RS15695	COG0523	cobalamin synthesis protein
BFW76_RS15700	COG0735	belongs to the Fur family
BFW76_RS15720	COG0803	Belongs to the bacterial solute-binding protein 9 family
BFW76_RS15730	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
BFW76_RS15740	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BFW76_RS15750	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BFW76_RS15755	COG1560	Kdo2-lipid A biosynthetic process
BFW76_RS15765	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BFW76_RS15780	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BFW76_RS15785	COG1950	PFAM Membrane protein of
BFW76_RS15800	COG0583	DNA-binding transcription factor activity
BFW76_RS15810	COG0477	Major facilitator Superfamily
BFW76_RS15825	COG0617	tRNA 3'-terminal CCA addition
BFW76_RS15835	COG0513	Belongs to the DEAD box helicase family
BFW76_RS15840	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BFW76_RS15850	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BFW76_RS15855	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BFW76_RS15915	COG1280	lysine exporter protein (LysE YggA)
BFW76_RS15930	COG0405	Gamma-glutamyltransferase
BFW76_RS15940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BFW76_RS15970	COG1309	transcriptional regulator
BFW76_RS15985	COG0745	RESPONSE REGULATOR receiver
BFW76_RS16035	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BFW76_RS16060	COG0582	viral genome integration into host DNA
BFW76_RS16065	COG0012	GTP binding
BFW76_RS16075	COG0193	aminoacyl-tRNA hydrolase activity
BFW76_RS16080	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BFW76_RS16085	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BFW76_RS16095	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BFW76_RS16100	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BFW76_RS16110	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BFW76_RS16135	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
BFW76_RS16145	COG1368	sulfuric ester hydrolase activity
BFW76_RS16150	COG0642	Histidine kinase
BFW76_RS16155	COG0745	RESPONSE REGULATOR receiver
BFW76_RS16160	COG0277	FAD linked oxidase domain protein
BFW76_RS16175	COG0166	Belongs to the GPI family
BFW76_RS16180	COG0438	transferase activity, transferring glycosyl groups
BFW76_RS16185	COG0438	transferase activity, transferring glycosyl groups
BFW76_RS16200	COG0438	transferase activity, transferring glycosyl groups
BFW76_RS16215	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BFW76_RS16220	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BFW76_RS16225	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
BFW76_RS16235	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BFW76_RS16245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BFW76_RS16250	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BFW76_RS16260	COG0747	negative chemotaxis
BFW76_RS16265	COG0601	transmembrane transport
BFW76_RS16270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BFW76_RS16290	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BFW76_RS16295	COG0830	nickel cation binding
BFW76_RS16305	COG0804	urea catabolic process
BFW76_RS16310	COG0832	Belongs to the urease beta subunit family
BFW76_RS16320	COG0831	urea catabolic process
BFW76_RS16325	COG0829	nickel cation binding
BFW76_RS16335	COG0633	Ferredoxin
BFW76_RS16350	COG2188	Transcriptional regulator
BFW76_RS16375	COG2719	SpoVR family
BFW76_RS16380	COG2718	Belongs to the UPF0229 family
BFW76_RS16395	COG1028	Short-chain dehydrogenase reductase Sdr
BFW76_RS16400	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BFW76_RS16415	COG1960	acyl-CoA dehydrogenase activity
BFW76_RS16460	COG0183	Belongs to the thiolase family
BFW76_RS16465	COG2030	dehydratase
BFW76_RS16510	COG0328	RNA-DNA hybrid ribonuclease activity
BFW76_RS16515	COG2226	methyltransferase
BFW76_RS16520	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BFW76_RS16525	COG0741	lytic transglycosylase activity
BFW76_RS16525	COG1388	LysM domain
BFW76_RS16545	COG2979	Protein of unknown function (DUF533)
BFW76_RS16580	COG1271	oxidase subunit
BFW76_RS16585	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BFW76_RS16590	COG0850	regulation of cytokinetic process
BFW76_RS16595	COG2894	cell division
BFW76_RS16600	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BFW76_RS16620	COG0488	(ABC) transporter
BFW76_RS16635	COG0601	transmembrane transport
BFW76_RS16645	COG1215	transferase activity, transferring glycosyl groups
BFW76_RS16660	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BFW76_RS16670	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BFW76_RS16690	COG0318	PFAM AMP-dependent synthetase and ligase
BFW76_RS16695	COG2188	Transcriptional regulator
BFW76_RS16700	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BFW76_RS16705	COG2814	Major facilitator Superfamily
BFW76_RS16715	COG0259	pyridoxamine-phosphate oxidase activity
BFW76_RS16720	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BFW76_RS16735	COG0583	DNA-binding transcription factor activity
BFW76_RS16740	COG1960	acyl-CoA dehydrogenase activity
BFW76_RS16760	COG0134	indole-3-glycerol-phosphate synthase activity
BFW76_RS16765	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BFW76_RS16770	COG0512	Glutamine amidotransferase of anthranilate synthase
BFW76_RS16780	COG0546	phosphoglycolate phosphatase activity
BFW76_RS16785	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BFW76_RS16790	COG2967	ApaG domain
BFW76_RS16795	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
BFW76_RS16800	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BFW76_RS16805	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BFW76_RS16810	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BFW76_RS16820	COG0037	tRNA processing
BFW76_RS16830	COG3634	alkyl hydroperoxide reductase activity
BFW76_RS16835	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BFW76_RS16840	COG1024	Enoyl-CoA hydratase
BFW76_RS16865	COG0356	it plays a direct role in the translocation of protons across the membrane
BFW76_RS16875	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BFW76_RS16880	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BFW76_RS16885	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BFW76_RS16890	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BFW76_RS16895	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BFW76_RS16900	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BFW76_RS16910	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BFW76_RS16915	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BFW76_RS16920	COG0210	DNA helicase
BFW76_RS16930	COG2195	Cleaves the N-terminal amino acid of tripeptides
BFW76_RS16940	COG4172	Belongs to the ABC transporter superfamily
BFW76_RS16945	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BFW76_RS16950	COG0601	transmembrane transport
BFW76_RS16970	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BFW76_RS16975	COG1024	Enoyl-CoA hydratase
BFW76_RS16980	COG1024	Enoyl-CoA hydratase
BFW76_RS17005	COG1250	3-hydroxyacyl-CoA dehydrogenase
BFW76_RS17040	COG2132	Multicopper oxidase
BFW76_RS17050	COG1024	Enoyl-CoA hydratase
BFW76_RS17050	COG1250	3-hydroxyacyl-CoA dehydrogenase
BFW76_RS17060	COG1414	Transcriptional regulator
BFW76_RS17070	COG0154	amidase activity
BFW76_RS17100	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BFW76_RS17105	COG3568	Endonuclease Exonuclease Phosphatase
BFW76_RS17110	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BFW76_RS17145	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BFW76_RS17155	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BFW76_RS17170	COG1137	ATPase activity
BFW76_RS17185	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BFW76_RS17190	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BFW76_RS17190	COG2010	Cytochrome c
BFW76_RS17200	COG1660	Displays ATPase and GTPase activities
BFW76_RS17205	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BFW76_RS17240	COG3181	Tripartite tricarboxylate transporter family receptor
BFW76_RS17250	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BFW76_RS17255	COG2890	protein-(glutamine-N5) methyltransferase activity
BFW76_RS17260	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BFW76_RS17265	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BFW76_RS17315	COG1960	acyl-CoA dehydrogenase activity
BFW76_RS17325	COG0183	Belongs to the thiolase family
BFW76_RS17330	COG1522	sequence-specific DNA binding
BFW76_RS17335	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BFW76_RS17355	COG1024	Enoyl-CoA hydratase
BFW76_RS17370	COG0604	alcohol dehydrogenase
BFW76_RS17390	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BFW76_RS17400	COG1960	acyl-CoA dehydrogenase activity
BFW76_RS17405	COG1960	acyl-CoA dehydrogenase activity
BFW76_RS17410	COG0277	FAD linked oxidase domain protein
BFW76_RS17420	COG3181	Tripartite tricarboxylate transporter family receptor
BFW76_RS17445	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BFW76_RS17455	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BFW76_RS17460	COG3181	Tripartite tricarboxylate transporter family receptor
BFW76_RS17465	COG1960	acyl-CoA dehydrogenase activity
BFW76_RS17485	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BFW76_RS17490	COG1024	Enoyl-CoA hydratase
BFW76_RS17495	COG1960	acyl-CoA dehydrogenase activity
BFW76_RS17515	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BFW76_RS17520	COG0022	dehydrogenase e1 component
BFW76_RS17525	COG1024	Enoyl-CoA hydratase
BFW76_RS17530	COG0508	dehydrogenase complex catalyzes the overall conversion of
BFW76_RS17550	COG0683	leucine binding
BFW76_RS17555	COG0559	Belongs to the binding-protein-dependent transport system permease family
BFW76_RS17560	COG0411	ABC transporter
BFW76_RS17570	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BFW76_RS17585	COG3181	Tripartite tricarboxylate transporter family receptor
BFW76_RS17610	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BFW76_RS17615	COG0793	Belongs to the peptidase S41A family
BFW76_RS17620	COG4942	peptidase
BFW76_RS17625	COG0588	phosphoglycerate mutase activity
BFW76_RS17630	COG1054	Belongs to the UPF0176 family
BFW76_RS17635	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BFW76_RS17640	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BFW76_RS17645	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BFW76_RS17650	COG3181	Tripartite tricarboxylate transporter family receptor
BFW76_RS17665	COG2226	methyltransferase
BFW76_RS17670	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
BFW76_RS17685	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BFW76_RS17690	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BFW76_RS17715	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BFW76_RS17740	COG1335	isochorismatase
BFW76_RS17745	COG2309	aminopeptidase activity
BFW76_RS17750	COG0596	Alpha beta hydrolase
BFW76_RS17755	COG3473	Maleate cis-trans isomerase
BFW76_RS17765	COG2068	MobA-Related Protein
BFW76_RS17790	COG2204	response regulator
BFW76_RS17795	COG5000	phosphorelay sensor kinase activity
BFW76_RS17805	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BFW76_RS17805	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BFW76_RS17815	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
BFW76_RS17845	COG0583	DNA-binding transcription factor activity
BFW76_RS17860	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BFW76_RS17865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BFW76_RS17870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BFW76_RS17885	COG0758	DNA mediated transformation
BFW76_RS17890	COG1522	sequence-specific DNA binding
BFW76_RS17900	COG0242	peptide deformylase activity
BFW76_RS17915	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BFW76_RS17925	COG0546	phosphoglycolate phosphatase activity
BFW76_RS17945	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BFW76_RS17950	COG1942	4-Oxalocrotonate Tautomerase
BFW76_RS17955	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BFW76_RS17980	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BFW76_RS18000	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BFW76_RS18005	COG1024	Enoyl-CoA hydratase
BFW76_RS18010	COG1414	Transcriptional regulator
BFW76_RS18015	COG0318	PFAM AMP-dependent synthetase and ligase
BFW76_RS18020	COG3181	Tripartite tricarboxylate transporter family receptor
BFW76_RS18050	COG0583	DNA-binding transcription factor activity
BFW76_RS18065	COG3422	double-strand break repair
BFW76_RS18070	COG0330	HflC and HflK could
BFW76_RS18080	COG0251	oxidation-reduction process
BFW76_RS18130	COG3723	Recombinational DNA repair protein, rece pathway
BFW76_RS18165	COG0582	viral genome integration into host DNA
BFW76_RS18190	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BFW76_RS18200	COG0706	membrane insertase activity
BFW76_RS18205	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BFW76_RS18210	COG0594	ribonuclease P activity
BFW76_RS18215	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BFW76_RS18220	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BFW76_RS18235	COG1414	Transcriptional regulator
BFW76_RS18240	COG0154	amidase activity
BFW76_RS18255	COG1304	FMN binding
BFW76_RS18275	COG1960	acyl-CoA dehydrogenase activity
BFW76_RS18295	COG1960	acyl-CoA dehydrogenase activity
BFW76_RS18310	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BFW76_RS18325	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BFW76_RS18330	COG3181	Tripartite tricarboxylate transporter family receptor
BFW76_RS18340	COG2358	TRAP transporter, solute receptor (TAXI family
BFW76_RS18350	COG1629	transport
BFW76_RS18355	COG2922	Belongs to the Smg family
BFW76_RS18380	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BFW76_RS18385	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BFW76_RS18390	COG1028	Short-chain dehydrogenase reductase Sdr
BFW76_RS18395	COG1012	belongs to the aldehyde dehydrogenase family
BFW76_RS18405	COG0028	Belongs to the TPP enzyme family
BFW76_RS18410	COG1522	sequence-specific DNA binding
BFW76_RS18415	COG3781	membrane
BFW76_RS18425	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BFW76_RS18445	COG4206	TonB-dependent receptor
BFW76_RS18450	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BFW76_RS18455	COG2022	thiamine diphosphate biosynthetic process
BFW76_RS18460	COG0351	phosphomethylpyrimidine kinase
BFW76_RS18465	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BFW76_RS18480	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BFW76_RS18490	COG0628	permease
BFW76_RS18500	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BFW76_RS18515	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BFW76_RS18520	COG0049	tRNA binding
BFW76_RS18525	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BFW76_RS18530	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BFW76_RS18535	COG0051	transcription antitermination factor activity, RNA binding
BFW76_RS18540	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BFW76_RS18545	COG0088	Forms part of the polypeptide exit tunnel
BFW76_RS18550	COG0089	rRNA binding
BFW76_RS18555	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BFW76_RS18560	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BFW76_RS18565	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BFW76_RS18570	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BFW76_RS18575	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BFW76_RS18580	COG0255	Belongs to the universal ribosomal protein uL29 family
BFW76_RS18585	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BFW76_RS18605	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BFW76_RS18610	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BFW76_RS18615	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BFW76_RS18620	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BFW76_RS18625	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BFW76_RS18630	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BFW76_RS18635	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BFW76_RS18640	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BFW76_RS18645	COG1841	ribosomal large subunit assembly
BFW76_RS18650	COG0200	Binds to the 23S rRNA
BFW76_RS18655	COG0201	protein transport
BFW76_RS18660	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BFW76_RS18665	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BFW76_RS18670	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BFW76_RS18675	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BFW76_RS18680	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BFW76_RS18685	COG0202	RNA polymerase activity
BFW76_RS18690	COG0203	ribosomal protein L17
BFW76_RS18695	COG0537	adenosine 5'-monophosphoramidase activity
BFW76_RS18700	COG1324	tolerance protein
BFW76_RS18705	COG4232	protein-disulfide reductase activity
BFW76_RS18720	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BFW76_RS18730	COG1333	cytochrome c biogenesis protein
BFW76_RS18735	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BFW76_RS18750	COG1965	Belongs to the frataxin family
BFW76_RS18760	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BFW76_RS18765	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BFW76_RS18770	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BFW76_RS18785	COG2814	Major facilitator Superfamily
BFW76_RS18790	COG0629	single-stranded DNA binding
BFW76_RS18830	COG0402	S-adenosylhomocysteine deaminase activity
BFW76_RS18840	COG0438	transferase activity, transferring glycosyl groups
BFW76_RS18860	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BFW76_RS18885	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BFW76_RS18890	COG2186	Transcriptional regulator
BFW76_RS18910	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BFW76_RS18915	COG1956	GAF domain-containing protein
BFW76_RS18920	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BFW76_RS18935	COG1652	LysM domain
BFW76_RS18950	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BFW76_RS18965	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BFW76_RS18995	COG3181	Tripartite tricarboxylate transporter family receptor
BFW76_RS19010	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BFW76_RS19025	COG1024	Enoyl-CoA hydratase
BFW76_RS19040	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BFW76_RS19045	COG1309	transcriptional regulator
BFW76_RS19050	COG2816	NAD+ diphosphatase activity
BFW76_RS19055	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BFW76_RS19140	COG2814	Major facilitator Superfamily
BFW76_RS19145	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BFW76_RS19165	COG1999	signal sequence binding
BFW76_RS19170	COG0109	protoheme IX farnesyltransferase activity
BFW76_RS19210	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BFW76_RS19230	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BFW76_RS19235	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BFW76_RS19245	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BFW76_RS19250	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
BFW76_RS19260	COG0067	glutamate synthase
BFW76_RS19260	COG0069	glutamate synthase activity
BFW76_RS19260	COG0070	glutamate synthase
BFW76_RS19270	COG3047	cAMP biosynthetic process
BFW76_RS19280	COG1127	ABC transporter
BFW76_RS19285	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BFW76_RS19290	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BFW76_RS19295	COG2853	Lipoprotein
BFW76_RS19305	COG1131	(ABC) transporter
BFW76_RS19310	COG0842	Transport permease protein
BFW76_RS19320	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BFW76_RS19325	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BFW76_RS19330	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BFW76_RS19335	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BFW76_RS19340	COG0131	Imidazoleglycerol-phosphate dehydratase
BFW76_RS19345	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BFW76_RS19350	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BFW76_RS19355	COG0107	imidazoleglycerol-phosphate synthase activity
BFW76_RS19360	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BFW76_RS19365	COG0140	phosphoribosyl-ATP diphosphatase activity
BFW76_RS19370	COG0537	adenosine 5'-monophosphoramidase activity
BFW76_RS19375	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BFW76_RS19380	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BFW76_RS19395	COG3181	Tripartite tricarboxylate transporter family receptor
BFW76_RS19430	COG3702	type iv secretory pathway
BFW76_RS19435	COG3451	type IV secretory pathway VirB4
BFW76_RS19450	COG3736	Type IV secretory pathway, component VirB8
BFW76_RS19455	COG3504	Conjugal transfer protein
BFW76_RS19460	COG2948	multi-organism process
BFW76_RS19465	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
BFW76_RS19475	COG0697	spore germination
BFW76_RS19495	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BFW76_RS19500	COG0747	negative chemotaxis
BFW76_RS19505	COG0601	transmembrane transport
BFW76_RS19510	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BFW76_RS19515	COG0444	Belongs to the ABC transporter superfamily
BFW76_RS19525	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BFW76_RS19535	COG0494	nUDIX hydrolase
BFW76_RS19575	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
BFW76_RS19580	COG0237	dephospho-CoA kinase activity
BFW76_RS19585	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BFW76_RS19600	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BFW76_RS19605	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BFW76_RS19615	COG0477	Major facilitator Superfamily
BFW76_RS19620	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BFW76_RS19635	COG1126	abc transporter atp-binding protein
BFW76_RS19640	COG0765	amino acid transport
BFW76_RS19645	COG4597	amino acid ABC transporter
BFW76_RS19650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BFW76_RS19655	COG2884	Cell division ATP-binding protein ftsE
BFW76_RS19660	COG2177	Part of the ABC transporter FtsEX involved in
BFW76_RS19665	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BFW76_RS19675	COG1194	a g-specific adenine glycosylase
BFW76_RS19685	COG2226	methyltransferase
BFW76_RS19695	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BFW76_RS19700	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BFW76_RS19715	COG1024	Enoyl-CoA hydratase
BFW76_RS19735	COG1024	Enoyl-CoA hydratase
BFW76_RS19740	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BFW76_RS19745	COG3181	Tripartite tricarboxylate transporter family receptor
BFW76_RS19755	COG0753	catalase activity
BFW76_RS19760	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BFW76_RS19765	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BFW76_RS19775	COG2175	clavaminate synthase activity
BFW76_RS19780	COG1473	amidohydrolase
BFW76_RS19785	COG4608	Belongs to the ABC transporter superfamily
BFW76_RS19790	COG0444	Belongs to the ABC transporter superfamily
BFW76_RS19805	COG0747	negative chemotaxis
BFW76_RS19810	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BFW76_RS19845	COG0436	Aminotransferase
BFW76_RS19850	COG1278	Cold shock