locus-tag	class	description
CX031_RS00005	COG0445	tRNA wobble uridine modification
CX031_RS00010	COG0357	Ribosomal RNA small subunit methyltransferase G
CX031_RS00015	COG1192	Involved in chromosome partitioning
CX031_RS00025	COG1475	DNA binding
CX031_RS00050	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CX031_RS00060	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CX031_RS00070	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CX031_RS00075	COG0081	regulation of translation
CX031_RS00080	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CX031_RS00085	COG0222	ribosome binding
CX031_RS00090	COG0085	RNA polymerase activity
CX031_RS00095	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CX031_RS00135	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX031_RS00160	COG1024	Enoyl-CoA hydratase
CX031_RS00180	COG0752	glycyl-tRNA synthetase alpha subunit
CX031_RS00185	COG0751	glycine-tRNA ligase activity
CX031_RS00190	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CX031_RS00195	COG0204	Acyl-transferase
CX031_RS00210	COG0242	peptide deformylase activity
CX031_RS00250	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CX031_RS00255	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CX031_RS00255	COG2813	Specifically methylates the guanine in position
CX031_RS00270	COG2223	nitrite transmembrane transporter activity
CX031_RS00280	COG1794	racemase activity, acting on amino acids and derivatives
CX031_RS00285	COG1126	abc transporter atp-binding protein
CX031_RS00290	COG0765	amino acid transport
CX031_RS00295	COG0765	amino acid transport
CX031_RS00300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CX031_RS00365	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CX031_RS00395	COG0326	Molecular chaperone. Has ATPase activity
CX031_RS00400	COG0625	glutathione transferase activity
CX031_RS00415	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CX031_RS00420	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CX031_RS00450	COG0438	transferase activity, transferring glycosyl groups
CX031_RS00455	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CX031_RS00460	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CX031_RS00490	COG0859	PFAM glycosyl transferase family 9
CX031_RS00505	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CX031_RS00515	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CX031_RS00520	COG1127	ABC transporter
CX031_RS00540	COG1686	Belongs to the peptidase S11 family
CX031_RS00550	COG2921	Belongs to the UPF0250 family
CX031_RS00555	COG0321	lipoyl(octanoyl) transferase activity
CX031_RS00560	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CX031_RS00595	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CX031_RS00605	COG0018	arginyl-trna synthetase
CX031_RS00625	COG0395	ABC-type sugar transport system, permease component
CX031_RS00630	COG1175	transmembrane transport
CX031_RS00635	COG1653	transport
CX031_RS00640	COG3842	ATPase activity
CX031_RS00645	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CX031_RS00655	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CX031_RS00675	COG1609	Transcriptional regulator
CX031_RS00685	COG0154	amidase activity
CX031_RS00690	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CX031_RS00700	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CX031_RS00710	COG0583	DNA-binding transcription factor activity
CX031_RS00730	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CX031_RS00745	COG1802	Transcriptional regulator
CX031_RS00760	COG1024	Enoyl-CoA hydratase
CX031_RS00770	COG3181	Tripartite tricarboxylate transporter family receptor
CX031_RS00785	COG1984	allophanate hydrolase subunit 2
CX031_RS00790	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CX031_RS00800	COG0583	DNA-binding transcription factor activity
CX031_RS00805	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CX031_RS00815	COG5002	protein histidine kinase activity
CX031_RS00825	COG5002	protein histidine kinase activity
CX031_RS00830	COG0745	RESPONSE REGULATOR receiver
CX031_RS00835	COG2226	methyltransferase
CX031_RS00850	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CX031_RS00870	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CX031_RS00880	COG0513	Belongs to the DEAD box helicase family
CX031_RS00885	COG1280	lysine exporter protein (LysE YggA)
CX031_RS00890	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CX031_RS00930	COG1054	Belongs to the UPF0176 family
CX031_RS00935	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CX031_RS00935	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CX031_RS00945	COG0489	protein tyrosine kinase activity
CX031_RS00960	COG0717	Belongs to the dCTP deaminase family
CX031_RS00990	COG2081	HI0933 family
CX031_RS01000	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CX031_RS01010	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CX031_RS01015	COG0509	glycine decarboxylation via glycine cleavage system
CX031_RS01020	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CX031_RS01020	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CX031_RS01060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CX031_RS01075	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CX031_RS01085	COG1414	Transcriptional regulator
CX031_RS01090	COG1028	Short-chain dehydrogenase reductase Sdr
CX031_RS01095	COG2031	fatty acid transporter
CX031_RS01100	COG1250	3-hydroxyacyl-CoA dehydrogenase
CX031_RS01110	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CX031_RS01115	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CX031_RS01125	COG4257	antibiotic catabolic process
CX031_RS01150	COG1012	belongs to the aldehyde dehydrogenase family
CX031_RS01155	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CX031_RS01160	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CX031_RS01185	COG1028	Short-chain dehydrogenase reductase Sdr
CX031_RS01195	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CX031_RS01205	COG2188	Transcriptional regulator
CX031_RS01210	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CX031_RS01235	COG0617	tRNA 3'-terminal CCA addition
CX031_RS01250	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CX031_RS01255	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CX031_RS01260	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CX031_RS01265	COG0586	Pfam SNARE associated Golgi protein
CX031_RS01270	COG0860	N-Acetylmuramoyl-L-alanine amidase
CX031_RS01275	COG0802	atpase or kinase
CX031_RS01280	COG0114	fumarate hydratase activity
CX031_RS01290	COG3181	Tripartite tricarboxylate transporter family receptor
CX031_RS01300	COG0405	Gamma-glutamyltransferase
CX031_RS01305	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX031_RS01335	COG1294	oxidase, subunit
CX031_RS01345	COG4988	ABC transporter
CX031_RS01350	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CX031_RS01400	COG2969	positive regulation of protein catabolic process
CX031_RS01405	COG0625	glutathione transferase activity
CX031_RS01410	COG2857	Cytochrome c1
CX031_RS01415	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CX031_RS01420	COG0723	plastoquinol--plastocyanin reductase activity
CX031_RS01425	COG1970	mechanosensitive ion channel activity
CX031_RS01430	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CX031_RS01445	COG2808	Putative FMN-binding domain
CX031_RS01450	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CX031_RS01455	COG0747	negative chemotaxis
CX031_RS01460	COG0657	acetylesterase activity
CX031_RS01470	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CX031_RS01475	COG2207	Transcriptional regulator
CX031_RS01480	COG0129	dihydroxy-acid dehydratase activity
CX031_RS01485	COG2814	Major facilitator Superfamily
CX031_RS01490	COG0583	DNA-binding transcription factor activity
CX031_RS01500	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
CX031_RS01570	COG1024	Enoyl-CoA hydratase
CX031_RS01575	COG1960	acyl-CoA dehydrogenase activity
CX031_RS01600	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CX031_RS01605	COG0352	thiamine-phosphate diphosphorylase activity
CX031_RS01620	COG1678	Uncharacterized ACR, COG1678
CX031_RS01625	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CX031_RS01630	COG0540	Belongs to the ATCase OTCase family
CX031_RS01645	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CX031_RS01655	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CX031_RS01690	COG1234	tRNA 3'-trailer cleavage
CX031_RS01710	COG3064	Membrane
CX031_RS01740	COG1683	Conserved Protein
CX031_RS01745	COG1120	ATPase activity
CX031_RS01750	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CX031_RS01755	COG4558	Periplasmic binding protein
CX031_RS01760	COG3720	iron ion transport
CX031_RS01770	COG3712	iron ion homeostasis
CX031_RS01775	COG1595	DNA-templated transcription, initiation
CX031_RS01810	COG1802	Transcriptional regulator
CX031_RS01820	COG3069	C4-dicarboxylate transmembrane transporter activity
CX031_RS01830	COG1012	belongs to the aldehyde dehydrogenase family
CX031_RS01865	COG2860	membrane
CX031_RS01870	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CX031_RS01875	COG0708	Exodeoxyribonuclease III
CX031_RS01880	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CX031_RS01885	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CX031_RS01890	COG0154	amidase activity
CX031_RS01895	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CX031_RS01900	COG1077	Cell shape determining protein MreB Mrl
CX031_RS01905	COG1792	Involved in formation and maintenance of cell shape
CX031_RS01915	COG0768	penicillin binding
CX031_RS01920	COG0772	Belongs to the SEDS family
CX031_RS01925	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CX031_RS01930	COG0471	metal ion transport
CX031_RS01935	COG1309	transcriptional regulator
CX031_RS01945	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CX031_RS01960	COG2823	Periplasmic or secreted lipoprotein
CX031_RS01965	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CX031_RS01980	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CX031_RS02000	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX031_RS02010	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX031_RS02030	COG0492	ferredoxin-NADP+ reductase activity
CX031_RS02040	COG3181	Tripartite tricarboxylate transporter family receptor
CX031_RS02045	COG1250	3-hydroxyacyl-CoA dehydrogenase
CX031_RS02045	COG1024	Enoyl-CoA hydratase
CX031_RS02050	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX031_RS02055	COG0028	Belongs to the TPP enzyme family
CX031_RS02080	COG3181	Tripartite tricarboxylate transporter family receptor
CX031_RS02095	COG0697	spore germination
CX031_RS02125	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CX031_RS02130	COG0463	Glycosyl transferase, family 2
CX031_RS02145	COG0786	glutamate:sodium symporter activity
CX031_RS02155	COG2031	fatty acid transporter
CX031_RS02170	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CX031_RS02200	COG3181	Tripartite tricarboxylate transporter family receptor
CX031_RS02210	COG0277	FAD linked oxidase domain protein
CX031_RS02215	COG1960	acyl-CoA dehydrogenase activity
CX031_RS02220	COG1960	acyl-CoA dehydrogenase activity
CX031_RS02230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CX031_RS02245	COG2072	flavoprotein involved in K transport
CX031_RS02250	COG0604	alcohol dehydrogenase
CX031_RS02265	COG1024	Enoyl-CoA hydratase
CX031_RS02285	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CX031_RS02290	COG1522	sequence-specific DNA binding
CX031_RS02295	COG0183	Belongs to the thiolase family
CX031_RS02305	COG1960	acyl-CoA dehydrogenase activity
CX031_RS02350	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CX031_RS02355	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CX031_RS02360	COG2890	protein-(glutamine-N5) methyltransferase activity
CX031_RS02365	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CX031_RS02375	COG3181	Tripartite tricarboxylate transporter family receptor
CX031_RS02410	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CX031_RS02415	COG1660	Displays ATPase and GTPase activities
CX031_RS02425	COG2010	Cytochrome c
CX031_RS02425	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CX031_RS02430	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CX031_RS02445	COG1137	ATPase activity
CX031_RS02460	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CX031_RS02470	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CX031_RS02505	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CX031_RS02510	COG3568	Endonuclease Exonuclease Phosphatase
CX031_RS02515	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CX031_RS02545	COG0154	amidase activity
CX031_RS02555	COG1414	Transcriptional regulator
CX031_RS02565	COG1250	3-hydroxyacyl-CoA dehydrogenase
CX031_RS02565	COG1024	Enoyl-CoA hydratase
CX031_RS02575	COG2132	Multicopper oxidase
CX031_RS02630	COG1024	Enoyl-CoA hydratase
CX031_RS02635	COG1024	Enoyl-CoA hydratase
CX031_RS02640	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CX031_RS02660	COG0601	transmembrane transport
CX031_RS02665	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CX031_RS02670	COG4172	Belongs to the ABC transporter superfamily
CX031_RS02680	COG2195	Cleaves the N-terminal amino acid of tripeptides
CX031_RS02690	COG0210	DNA helicase
CX031_RS02695	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CX031_RS02700	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CX031_RS02710	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CX031_RS02715	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CX031_RS02720	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CX031_RS02725	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CX031_RS02730	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CX031_RS02735	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CX031_RS02745	COG0356	it plays a direct role in the translocation of protons across the membrane
CX031_RS02770	COG1024	Enoyl-CoA hydratase
CX031_RS02775	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CX031_RS02780	COG3634	alkyl hydroperoxide reductase activity
CX031_RS02790	COG0037	tRNA processing
CX031_RS02800	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CX031_RS02805	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CX031_RS02810	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CX031_RS02815	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CX031_RS02820	COG2967	ApaG domain
CX031_RS02825	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CX031_RS02830	COG0546	phosphoglycolate phosphatase activity
CX031_RS02840	COG0512	Glutamine amidotransferase of anthranilate synthase
CX031_RS02845	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CX031_RS02850	COG0134	indole-3-glycerol-phosphate synthase activity
CX031_RS02875	COG0583	DNA-binding transcription factor activity
CX031_RS02890	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CX031_RS02895	COG0259	pyridoxamine-phosphate oxidase activity
CX031_RS02905	COG2814	Major facilitator Superfamily
CX031_RS02910	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CX031_RS02915	COG2188	Transcriptional regulator
CX031_RS02920	COG0318	PFAM AMP-dependent synthetase and ligase
CX031_RS02940	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CX031_RS02950	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CX031_RS02965	COG1215	transferase activity, transferring glycosyl groups
CX031_RS02975	COG0601	transmembrane transport
CX031_RS03010	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CX031_RS03015	COG2894	cell division
CX031_RS03020	COG0850	regulation of cytokinetic process
CX031_RS03025	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CX031_RS03030	COG1271	oxidase subunit
CX031_RS03065	COG2979	Protein of unknown function (DUF533)
CX031_RS03085	COG0741	lytic transglycosylase activity
CX031_RS03085	COG1388	LysM domain
CX031_RS03090	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CX031_RS03095	COG2226	methyltransferase
CX031_RS03100	COG0328	RNA-DNA hybrid ribonuclease activity
CX031_RS03150	COG2030	dehydratase
CX031_RS03200	COG1960	acyl-CoA dehydrogenase activity
CX031_RS03215	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX031_RS03235	COG2718	Belongs to the UPF0229 family
CX031_RS03240	COG2719	SpoVR family
CX031_RS03265	COG2188	Transcriptional regulator
CX031_RS03295	COG0829	nickel cation binding
CX031_RS03300	COG0831	urea catabolic process
CX031_RS03310	COG0832	Belongs to the urease beta subunit family
CX031_RS03315	COG0804	urea catabolic process
CX031_RS03325	COG0830	nickel cation binding
CX031_RS03330	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CX031_RS03350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CX031_RS03355	COG0601	transmembrane transport
CX031_RS03360	COG0747	negative chemotaxis
CX031_RS03370	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CX031_RS03375	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CX031_RS03385	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CX031_RS03395	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
CX031_RS03400	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CX031_RS03405	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CX031_RS03420	COG0438	transferase activity, transferring glycosyl groups
CX031_RS03435	COG0438	transferase activity, transferring glycosyl groups
CX031_RS03440	COG0438	transferase activity, transferring glycosyl groups
CX031_RS03445	COG0166	Belongs to the GPI family
CX031_RS03460	COG0277	FAD linked oxidase domain protein
CX031_RS03465	COG0745	RESPONSE REGULATOR receiver
CX031_RS03470	COG0642	Histidine kinase
CX031_RS03475	COG1368	sulfuric ester hydrolase activity
CX031_RS03485	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CX031_RS03510	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CX031_RS03520	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CX031_RS03525	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CX031_RS03535	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CX031_RS03540	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CX031_RS03545	COG0193	aminoacyl-tRNA hydrolase activity
CX031_RS03555	COG0012	GTP binding
CX031_RS03560	COG0582	viral genome integration into host DNA
CX031_RS03585	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CX031_RS03650	COG0745	RESPONSE REGULATOR receiver
CX031_RS03665	COG1309	transcriptional regulator
CX031_RS03695	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CX031_RS03705	COG0405	Gamma-glutamyltransferase
CX031_RS03780	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CX031_RS03785	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CX031_RS03795	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CX031_RS03800	COG0513	Belongs to the DEAD box helicase family
CX031_RS03810	COG0617	tRNA 3'-terminal CCA addition
CX031_RS03825	COG0477	Major facilitator Superfamily
CX031_RS03835	COG0583	DNA-binding transcription factor activity
CX031_RS03850	COG1950	PFAM Membrane protein of
CX031_RS03855	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CX031_RS03870	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CX031_RS03880	COG1560	Kdo2-lipid A biosynthetic process
CX031_RS03885	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CX031_RS03895	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CX031_RS03905	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CX031_RS03915	COG0803	Belongs to the bacterial solute-binding protein 9 family
CX031_RS03930	COG0735	belongs to the Fur family
CX031_RS03935	COG0523	cobalamin synthesis protein
CX031_RS03945	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CX031_RS03950	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CX031_RS03965	COG2096	Adenosyltransferase
CX031_RS03985	COG2084	Dehydrogenase
CX031_RS04035	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CX031_RS04040	COG0129	dihydroxy-acid dehydratase activity
CX031_RS04045	COG4654	Cytochrome c, class I
CX031_RS04050	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CX031_RS04100	COG1473	amidohydrolase
CX031_RS04105	COG0418	dihydroorotase activity
CX031_RS04110	COG0488	(ABC) transporter
CX031_RS04120	COG2001	Belongs to the MraZ family
CX031_RS04125	COG0275	rRNA processing
CX031_RS04130	COG3116	cell division
CX031_RS04140	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CX031_RS04145	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CX031_RS04150	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CX031_RS04160	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CX031_RS04165	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CX031_RS04170	COG1181	Belongs to the D-alanine--D-alanine ligase family
CX031_RS04175	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CX031_RS04185	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CX031_RS04190	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CX031_RS04200	COG0739	heme binding
CX031_RS04205	COG0653	protein targeting
CX031_RS04225	COG1028	Short-chain dehydrogenase reductase Sdr
CX031_RS04230	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CX031_RS04235	COG1522	sequence-specific DNA binding
CX031_RS04255	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CX031_RS04265	COG0557	exoribonuclease II activity
CX031_RS04270	COG3150	esterase
CX031_RS04275	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CX031_RS04280	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CX031_RS04285	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CX031_RS04290	COG0511	ligase activity, forming carbon-carbon bonds
CX031_RS04295	COG0439	Biotin carboxylase
CX031_RS04310	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CX031_RS04335	COG1696	Membrane protein involved in D-alanine export
CX031_RS04340	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CX031_RS04375	COG1522	sequence-specific DNA binding
CX031_RS04390	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CX031_RS04395	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CX031_RS04395	COG1042	CoA-binding domain protein
CX031_RS04395	COG0045	succinate-CoA ligase (ADP-forming) activity
CX031_RS04410	COG1802	Transcriptional regulator
CX031_RS04415	COG3069	C4-dicarboxylate transmembrane transporter activity
CX031_RS04420	COG0513	Belongs to the DEAD box helicase family
CX031_RS04425	COG0346	lactoylglutathione lyase activity
CX031_RS04430	COG1335	isochorismatase
CX031_RS04435	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CX031_RS04440	COG1116	anion transmembrane transporter activity
CX031_RS04455	COG3028	Belongs to the UPF0307 family
CX031_RS04460	COG0312	modulator of DNA gyrase
CX031_RS04465	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CX031_RS04470	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CX031_RS04475	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CX031_RS04480	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CX031_RS04490	COG0316	Belongs to the HesB IscA family
CX031_RS04495	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CX031_RS04510	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CX031_RS04520	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CX031_RS04525	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CX031_RS04540	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CX031_RS04540	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CX031_RS04575	COG0583	DNA-binding transcription factor activity
CX031_RS04580	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX031_RS04615	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CX031_RS04625	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CX031_RS04630	COG1845	cytochrome c oxidase, subunit III
CX031_RS04635	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CX031_RS04640	COG0640	Transcriptional regulator
CX031_RS04660	COG3220	belongs to the UPF0276 family
CX031_RS04705	COG1666	GTP binding
CX031_RS04740	COG0312	modulator of DNA gyrase
CX031_RS04745	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CX031_RS04750	COG3064	Membrane
CX031_RS04750	COG3210	domain, Protein
CX031_RS04750	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CX031_RS04750	COG3064	Membrane
CX031_RS04750	COG3210	domain, Protein
CX031_RS04750	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CX031_RS04755	COG0277	FAD linked oxidase domain protein
CX031_RS04760	COG0277	FAD linked oxidase domain protein
CX031_RS04765	COG0277	FAD linked oxidase domain protein
CX031_RS04770	COG0247	lactate metabolic process
CX031_RS04775	COG2819	hydrolase of the alpha beta superfamily
CX031_RS04815	COG0583	DNA-binding transcription factor activity
CX031_RS04820	COG0482	sulfurtransferase activity
CX031_RS04825	COG0730	response to heat
CX031_RS04830	COG0625	glutathione transferase activity
CX031_RS04835	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CX031_RS04840	COG3909	cytochrome
CX031_RS04880	COG0154	amidase activity
CX031_RS04885	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX031_RS04890	COG1024	Enoyl-CoA hydratase
CX031_RS04905	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CX031_RS04920	COG1028	Short-chain dehydrogenase reductase Sdr
CX031_RS04925	COG1414	Transcriptional regulator
CX031_RS04935	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CX031_RS04940	COG0251	oxidation-reduction process
CX031_RS04945	COG0559	Belongs to the binding-protein-dependent transport system permease family
CX031_RS04980	COG0583	DNA-binding transcription factor activity
CX031_RS04990	COG0590	tRNA wobble adenosine to inosine editing
CX031_RS04995	COG2807	transmembrane transport
CX031_RS05015	COG0154	amidase activity
CX031_RS05020	COG0307	riboflavin synthase, alpha
CX031_RS05025	COG3181	Tripartite tricarboxylate transporter family receptor
CX031_RS05030	COG1522	sequence-specific DNA binding
CX031_RS05040	COG0318	PFAM AMP-dependent synthetase and ligase
CX031_RS05050	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CX031_RS05070	COG1063	alcohol dehydrogenase
CX031_RS05095	COG1418	mRNA catabolic process
CX031_RS05100	COG1448	Aminotransferase
CX031_RS05105	COG0583	DNA-binding transcription factor activity
CX031_RS05115	COG0477	Major facilitator Superfamily
CX031_RS05120	COG1028	Short-chain dehydrogenase reductase Sdr
CX031_RS05135	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CX031_RS05140	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CX031_RS05145	COG0583	DNA-binding transcription factor activity
CX031_RS05205	COG1028	Short-chain dehydrogenase reductase Sdr
CX031_RS05210	COG1309	transcriptional regulator
CX031_RS05220	COG2982	Protein involved in outer membrane biogenesis
CX031_RS05225	COG2818	Glycosylase
CX031_RS05245	COG1653	transport
CX031_RS05260	COG3842	ATPase activity
CX031_RS05265	COG0395	ABC-type sugar transport system, permease component
CX031_RS05270	COG1175	transmembrane transport
CX031_RS05290	COG3181	Tripartite tricarboxylate transporter family receptor
CX031_RS05295	COG2186	Transcriptional regulator
CX031_RS05325	COG1454	alcohol dehydrogenase
CX031_RS05345	COG2011	ABC-type metal ion transport system permease component
CX031_RS05350	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CX031_RS05355	COG1501	Belongs to the glycosyl hydrolase 31 family
CX031_RS05380	COG0318	PFAM AMP-dependent synthetase and ligase
CX031_RS05385	COG1473	amidohydrolase
CX031_RS05395	COG2855	membrane
CX031_RS05405	COG2239	Acts as a magnesium transporter
CX031_RS05425	COG3181	Tripartite tricarboxylate transporter family receptor
CX031_RS05435	COG1722	exodeoxyribonuclease VII activity
CX031_RS05440	COG0142	geranyltranstransferase activity
CX031_RS05445	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CX031_RS05450	COG1469	GTP cyclohydrolase I activity
CX031_RS05455	COG0360	Binds together with S18 to 16S ribosomal RNA
CX031_RS05460	COG2965	DNA replication, synthesis of RNA primer
CX031_RS05465	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CX031_RS05470	COG0359	binds to the 23S rRNA
CX031_RS05480	COG0305	Participates in initiation and elongation during chromosome replication
CX031_RS05490	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CX031_RS05495	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CX031_RS05500	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CX031_RS05505	COG3737	Protein of unknown function (DUF498/DUF598)
CX031_RS05510	COG0436	Aminotransferase
CX031_RS05535	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CX031_RS05570	COG0268	Binds directly to 16S ribosomal RNA
CX031_RS05580	COG0728	peptidoglycan biosynthetic process
CX031_RS05590	COG0563	adenylate kinase activity
CX031_RS05595	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CX031_RS05600	COG2835	tetraacyldisaccharide 4'-kinase activity
CX031_RS05605	COG1663	tetraacyldisaccharide 4'-kinase activity
CX031_RS05610	COG0848	biopolymer transport protein
CX031_RS05615	COG0811	peptide transport
CX031_RS05625	COG1570	exodeoxyribonuclease VII activity
CX031_RS05630	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CX031_RS05635	COG0038	chloride channel
CX031_RS05640	COG0183	Belongs to the thiolase family
CX031_RS05650	COG1278	Cold shock
CX031_RS05655	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CX031_RS05665	COG4953	penicillin-binding protein 1C
CX031_RS05670	COG0542	response to heat
CX031_RS05675	COG2995	paraquat-inducible protein a
CX031_RS05680	COG3008	intermembrane lipid transfer
CX031_RS05680	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CX031_RS05690	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CX031_RS05690	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CX031_RS05690	COG0506	proline dehydrogenase activity
CX031_RS05725	COG2271	Major facilitator Superfamily
CX031_RS05730	COG1309	transcriptional regulator
CX031_RS05765	COG0477	Major facilitator Superfamily
CX031_RS05775	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CX031_RS05780	COG1845	cytochrome c oxidase, subunit III
CX031_RS05785	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CX031_RS05795	COG1028	Short-chain dehydrogenase reductase Sdr
CX031_RS05815	COG0789	Transcriptional regulator
CX031_RS05840	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CX031_RS05845	COG0697	spore germination
CX031_RS05855	COG0678	peroxiredoxin activity
CX031_RS05865	COG0412	Dienelactone hydrolase
CX031_RS05875	COG0315	cyclic pyranopterin monophosphate synthase activity
CX031_RS05890	COG0521	Mo-molybdopterin cofactor biosynthetic process
CX031_RS05895	COG0303	'Molybdopterin
CX031_RS05900	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CX031_RS05920	COG0165	Argininosuccinate lyase
CX031_RS05925	COG0668	transmembrane transport
CX031_RS05970	COG0747	negative chemotaxis
CX031_RS05975	COG0601	transmembrane transport
CX031_RS05990	COG1162	GTPase activity
CX031_RS05995	COG0501	Belongs to the peptidase M48B family
CX031_RS06000	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CX031_RS06010	COG3327	negative regulation of DNA-templated transcription, initiation
CX031_RS06015	COG3396	Phenylacetate-CoA oxygenase
CX031_RS06020	COG3460	Phenylacetate-CoA oxygenase
CX031_RS06025	COG3396	Phenylacetate-CoA oxygenase
CX031_RS06030	COG2151	metal-sulfur cluster biosynthetic enzyme
CX031_RS06050	COG1012	belongs to the aldehyde dehydrogenase family
CX031_RS06055	COG1024	Enoyl-CoA hydratase
CX031_RS06060	COG2050	protein possibly involved in aromatic compounds catabolism
CX031_RS06070	COG3539	Fimbrial protein
CX031_RS06090	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CX031_RS06095	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CX031_RS06095	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CX031_RS06100	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CX031_RS06105	COG0047	phosphoribosylformylglycinamidine synthase activity
CX031_RS06105	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CX031_RS06110	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CX031_RS06110	COG3210	domain, Protein
CX031_RS06110	COG3064	Membrane
CX031_RS06140	COG0235	Class ii aldolase
CX031_RS06145	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CX031_RS06150	COG0720	synthase
CX031_RS06155	COG0602	queuosine metabolic process
CX031_RS06180	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CX031_RS06215	COG3181	Tripartite tricarboxylate transporter family receptor
CX031_RS06240	COG3842	ATPase activity
CX031_RS06250	COG0395	ABC-type sugar transport system, permease component
CX031_RS06280	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CX031_RS06285	COG0420	3'-5' exonuclease activity
CX031_RS06330	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CX031_RS06330	COG0519	Catalyzes the synthesis of GMP from XMP
CX031_RS06345	COG3550	peptidyl-serine autophosphorylation
CX031_RS06355	COG0477	Major facilitator Superfamily
CX031_RS06370	COG1228	amidohydrolase
CX031_RS06380	COG1116	anion transmembrane transporter activity
CX031_RS06385	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CX031_RS06420	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CX031_RS06440	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CX031_RS06470	COG2814	Major facilitator Superfamily
CX031_RS06485	COG1280	lysine exporter protein (LysE YggA)
CX031_RS06500	COG0747	negative chemotaxis
CX031_RS06505	COG0601	transmembrane transport
CX031_RS06510	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CX031_RS06515	COG4172	Belongs to the ABC transporter superfamily
CX031_RS06520	COG1609	Transcriptional regulator
CX031_RS06550	COG0586	Pfam SNARE associated Golgi protein
CX031_RS06565	COG0500	methyltransferase
CX031_RS06580	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CX031_RS06590	COG0756	dUTP diphosphatase activity
CX031_RS06600	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CX031_RS06605	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CX031_RS06610	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CX031_RS06615	COG0072	phenylalanine-tRNA ligase activity
CX031_RS06615	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CX031_RS06620	COG0776	regulation of translation
CX031_RS06685	COG0540	Belongs to the ATCase OTCase family
CX031_RS06690	COG2974	May be involved in recombination
CX031_RS06700	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX031_RS06705	COG0583	DNA-binding transcription factor activity
CX031_RS06725	COG1028	Short-chain dehydrogenase reductase Sdr
CX031_RS06740	COG3842	ATPase activity
CX031_RS06745	COG1250	3-hydroxyacyl-CoA dehydrogenase
CX031_RS06745	COG1024	Enoyl-CoA hydratase
CX031_RS06765	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CX031_RS06770	COG2137	regulation of response to DNA damage stimulus
CX031_RS06780	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CX031_RS06790	COG0045	succinate-CoA ligase (ADP-forming) activity
CX031_RS06795	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CX031_RS06800	COG0861	Integral membrane protein TerC family
CX031_RS06805	COG0861	Integral membrane protein TerC family
CX031_RS06810	COG0181	hydroxymethylbilane synthase activity
CX031_RS06870	COG4964	Belongs to the GSP D family
CX031_RS06895	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CX031_RS06905	COG0583	DNA-binding transcription factor activity
CX031_RS06915	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CX031_RS06920	COG4311	Sarcosine oxidase, delta subunit
CX031_RS06925	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CX031_RS06925	COG0446	pyridine nucleotide-disulphide oxidoreductase
CX031_RS06960	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CX031_RS06965	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CX031_RS06970	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CX031_RS06975	COG0735	belongs to the Fur family
CX031_RS06980	COG0497	DNA recombination
CX031_RS06985	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CX031_RS06990	COG1420	regulation of RNA biosynthetic process
CX031_RS06995	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CX031_RS07005	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CX031_RS07015	COG0443	Heat shock 70 kDa protein
CX031_RS07025	COG0612	Peptidase, M16
CX031_RS07045	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CX031_RS07090	COG0745	RESPONSE REGULATOR receiver
CX031_RS07100	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CX031_RS07105	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CX031_RS07110	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CX031_RS07125	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CX031_RS07145	COG1193	negative regulation of DNA recombination
CX031_RS07150	COG0492	ferredoxin-NADP+ reductase activity
CX031_RS07155	COG1674	ftsk spoiiie
CX031_RS07160	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CX031_RS07165	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CX031_RS07170	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CX031_RS07195	COG3706	GGDEF domain
CX031_RS07215	COG2814	Major facilitator Superfamily
CX031_RS07245	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CX031_RS07260	COG1028	Short-chain dehydrogenase reductase Sdr
CX031_RS07270	COG3022	response to hydroperoxide
CX031_RS07310	COG2197	response regulator
CX031_RS07315	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CX031_RS07320	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CX031_RS07325	COG0189	ligase activity
CX031_RS07335	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CX031_RS07340	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CX031_RS07355	COG2423	ornithine cyclodeaminase activity
CX031_RS07365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CX031_RS07370	COG0765	amino acid transport
CX031_RS07375	COG0765	amino acid transport
CX031_RS07380	COG1126	abc transporter atp-binding protein
CX031_RS07435	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CX031_RS07445	COG2944	sequence-specific DNA binding
CX031_RS07455	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CX031_RS07460	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CX031_RS07465	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CX031_RS07470	COG0009	L-threonylcarbamoyladenylate synthase
CX031_RS07475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CX031_RS07480	COG1414	Transcriptional regulator
CX031_RS07495	COG0765	amino acid transport
CX031_RS07500	COG1126	abc transporter atp-binding protein
CX031_RS07505	COG0028	Belongs to the TPP enzyme family
CX031_RS07520	COG0028	Belongs to the TPP enzyme family
CX031_RS07525	COG0583	DNA-binding transcription factor activity
CX031_RS07530	COG4974	Belongs to the 'phage' integrase family
CX031_RS07535	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CX031_RS07540	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CX031_RS07555	COG1686	Belongs to the peptidase S11 family
CX031_RS07565	COG2814	Major facilitator Superfamily
CX031_RS07575	COG1074	ATP-dependent DNA helicase activity
CX031_RS07585	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CX031_RS07590	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CX031_RS07595	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CX031_RS07615	COG2321	neutral zinc metallopeptidase
CX031_RS07620	COG0009	L-threonylcarbamoyladenylate synthase
CX031_RS07665	COG3360	Dodecin
CX031_RS07670	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CX031_RS07675	COG2850	peptidyl-arginine hydroxylation
CX031_RS07680	COG3539	Fimbrial protein
CX031_RS07685	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CX031_RS07690	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CX031_RS07705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CX031_RS07710	COG0765	amino acid transport
CX031_RS07715	COG1126	abc transporter atp-binding protein
CX031_RS07720	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CX031_RS07725	COG1758	RNA polymerase activity
CX031_RS07730	COG0194	GDP metabolic process
CX031_RS07735	COG3258	Cytochrome c
CX031_RS07740	COG2863	cytochrome
CX031_RS07745	COG1028	Short-chain dehydrogenase reductase Sdr
CX031_RS07750	COG0791	NLP P60 protein
CX031_RS07755	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CX031_RS07775	COG1561	YicC-like family, N-terminal region
CX031_RS07780	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CX031_RS07800	COG2199	diguanylate cyclase activity
CX031_RS07800	COG2200	EAL domain
CX031_RS07805	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CX031_RS07815	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CX031_RS07820	COG0174	glutamine synthetase
CX031_RS07830	COG2204	response regulator
CX031_RS07835	COG0583	DNA-binding transcription factor activity
CX031_RS07840	COG1741	Belongs to the pirin family
CX031_RS07845	COG1741	Belongs to the pirin family
CX031_RS07855	COG3842	ATPase activity
CX031_RS07860	COG1178	ABC-type Fe3 transport system permease component
CX031_RS07865	COG1840	ABC-type Fe3 transport system, periplasmic component
CX031_RS07875	COG0583	DNA-binding transcription factor activity
CX031_RS07885	COG0656	L-ascorbic acid biosynthetic process
CX031_RS07900	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CX031_RS07905	COG0583	DNA-binding transcription factor activity
CX031_RS07920	COG0783	Belongs to the Dps family
CX031_RS07940	COG0463	Glycosyl transferase, family 2
CX031_RS07960	COG0438	transferase activity, transferring glycosyl groups
CX031_RS07975	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CX031_RS08000	COG0300	oxidoreductase activity
CX031_RS08045	COG0861	Integral membrane protein TerC family
CX031_RS08050	COG1028	Short-chain dehydrogenase reductase Sdr
CX031_RS08070	COG0714	Associated with various cellular activities
CX031_RS08105	COG3119	arylsulfatase activity
CX031_RS08130	COG2197	response regulator
CX031_RS08140	COG2944	sequence-specific DNA binding
CX031_RS08150	COG0625	glutathione transferase activity
CX031_RS08180	COG0179	Fumarylacetoacetate (FAA) hydrolase
CX031_RS08185	COG1028	Short-chain dehydrogenase reductase Sdr
CX031_RS08230	COG0431	NADPH-dependent FMN reductase
CX031_RS08260	COG1028	Short-chain dehydrogenase reductase Sdr
CX031_RS08265	COG0583	DNA-binding transcription factor activity
CX031_RS08285	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CX031_RS08285	COG2111	Na H antiporter
CX031_RS08290	COG1006	Multisubunit Na H antiporter MnhC subunit
CX031_RS08295	COG0651	ATP synthesis coupled electron transport
CX031_RS08300	COG1863	multisubunit Na H antiporter MnhE subunit
CX031_RS08305	COG2212	antiporter activity
CX031_RS08330	COG0590	tRNA wobble adenosine to inosine editing
CX031_RS08335	COG1619	proteins homologs of microcin C7 resistance protein MccF
CX031_RS08340	COG1024	Enoyl-CoA hydratase
CX031_RS08355	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CX031_RS08360	COG0488	(ABC) transporter
CX031_RS08395	COG1017	nitric oxide dioxygenase activity
CX031_RS08395	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CX031_RS08400	COG1959	2 iron, 2 sulfur cluster binding
CX031_RS08405	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CX031_RS08425	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CX031_RS08430	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CX031_RS08435	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CX031_RS08440	COG0084	hydrolase, TatD family'
CX031_RS08455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CX031_RS08465	COG1126	abc transporter atp-binding protein
CX031_RS08475	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CX031_RS08490	COG0028	Belongs to the TPP enzyme family
CX031_RS08500	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CX031_RS08500	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CX031_RS08510	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CX031_RS08560	COG4336	lyase activity
CX031_RS08570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CX031_RS08570	COG2205	protein histidine kinase activity
CX031_RS08575	COG2197	response regulator
CX031_RS08580	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CX031_RS08580	COG3210	domain, Protein
CX031_RS08580	COG3064	Membrane
CX031_RS08590	COG3121	Chaperone
CX031_RS08595	COG3188	usher protein
CX031_RS08600	COG3539	Fimbrial protein
CX031_RS08605	COG2831	hemolysin activation secretion protein
CX031_RS08620	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CX031_RS08670	COG0668	transmembrane transport
CX031_RS08690	COG0483	inositol monophosphate 1-phosphatase activity
CX031_RS08695	COG1253	flavin adenine dinucleotide binding
CX031_RS08700	COG1968	undecaprenyl-diphosphatase activity
CX031_RS08705	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CX031_RS08720	COG0215	cysteine-tRNA ligase activity
CX031_RS08730	COG0825	malonyl-CoA metabolic process
CX031_RS08740	COG0037	tRNA processing
CX031_RS08745	COG0527	aspartate kinase activity
CX031_RS08770	COG1250	3-hydroxyacyl-CoA dehydrogenase
CX031_RS08775	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CX031_RS08775	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CX031_RS08790	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CX031_RS08795	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
CX031_RS08800	COG1028	Short-chain dehydrogenase reductase Sdr
CX031_RS08810	COG0583	DNA-binding transcription factor activity
CX031_RS08835	COG3842	ATPase activity
CX031_RS08845	COG0446	pyridine nucleotide-disulphide oxidoreductase
CX031_RS08845	COG1902	pentaerythritol trinitrate reductase activity
CX031_RS08850	COG1414	Transcriptional regulator
CX031_RS08855	COG1832	CoA-binding protein
CX031_RS08865	COG0251	oxidation-reduction process
CX031_RS08890	COG1902	pentaerythritol trinitrate reductase activity
CX031_RS08900	COG1215	transferase activity, transferring glycosyl groups
CX031_RS08905	COG1649	PFAM Uncharacterised BCR, COG1649
CX031_RS08905	COG0726	polysaccharide deacetylase
CX031_RS08925	COG1846	Transcriptional regulator
CX031_RS08930	COG2197	response regulator
CX031_RS08945	COG0166	Belongs to the GPI family
CX031_RS08950	COG1045	serine acetyltransferase
CX031_RS08960	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CX031_RS08965	COG0483	inositol monophosphate 1-phosphatase activity
CX031_RS08970	COG1012	belongs to the aldehyde dehydrogenase family
CX031_RS08975	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CX031_RS08990	COG0210	DNA helicase
CX031_RS08995	COG0598	Magnesium transport protein CorA
CX031_RS09005	COG0747	negative chemotaxis
CX031_RS09010	COG0601	transmembrane transport
CX031_RS09015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CX031_RS09020	COG4172	Belongs to the ABC transporter superfamily
CX031_RS09025	COG1846	Transcriptional regulator
CX031_RS09080	COG4964	Belongs to the GSP D family
CX031_RS09120	COG2204	response regulator
CX031_RS09135	COG1595	DNA-templated transcription, initiation
CX031_RS09145	COG3474	cytochrome
CX031_RS09150	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CX031_RS09165	COG3384	dioxygenase
CX031_RS09170	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CX031_RS09200	COG2885	chlorophyll binding
CX031_RS09235	COG0697	spore germination
CX031_RS09240	COG0730	response to heat
CX031_RS09260	COG0583	DNA-binding transcription factor activity
CX031_RS09265	COG0427	acetyl-CoA hydrolase
CX031_RS09320	COG1250	3-hydroxyacyl-CoA dehydrogenase
CX031_RS09325	COG0154	amidase activity
CX031_RS09335	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CX031_RS09350	COG0495	leucyl-tRNA aminoacylation
CX031_RS09355	COG2814	Major facilitator Superfamily
CX031_RS09390	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CX031_RS09395	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CX031_RS09400	COG2814	Major facilitator Superfamily
CX031_RS09420	COG4176	ABC-type proline glycine betaine transport system permease component
CX031_RS09430	COG1942	4-Oxalocrotonate Tautomerase
CX031_RS09435	COG0183	Belongs to the thiolase family
CX031_RS09445	COG1802	Transcriptional regulator
CX031_RS09455	COG1024	Enoyl-CoA hydratase
CX031_RS09470	COG2032	superoxide dismutase activity
CX031_RS09485	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CX031_RS09510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CX031_RS09515	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CX031_RS09525	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CX031_RS09530	COG0736	holo-[acyl-carrier-protein] synthase activity
CX031_RS09535	COG1472	Belongs to the glycosyl hydrolase 3 family
CX031_RS09540	COG0322	excinuclease ABC activity
CX031_RS09545	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CX031_RS09555	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CX031_RS09555	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CX031_RS09560	COG2224	Isocitrate lyase
CX031_RS09585	COG0559	Belongs to the binding-protein-dependent transport system permease family
CX031_RS09595	COG4638	Rieske (2fe-2S)
CX031_RS09605	COG1024	Enoyl-CoA hydratase
CX031_RS09615	COG0633	Ferredoxin
CX031_RS09620	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX031_RS09635	COG0183	Belongs to the thiolase family
CX031_RS09650	COG0583	DNA-binding transcription factor activity
CX031_RS09680	COG2346	COG2346, Truncated hemoglobins
CX031_RS09810	COG2207	Transcriptional regulator
CX031_RS09860	COG1132	(ABC) transporter
CX031_RS09885	COG0659	secondary active sulfate transmembrane transporter activity
CX031_RS09915	COG2169	Transcriptional regulator
CX031_RS09920	COG5507	3-demethylubiquinone-9 3-methyltransferase
CX031_RS09925	COG0384	phenazine biosynthesis protein PhzF
CX031_RS09930	COG0583	DNA-binding transcription factor activity
CX031_RS09935	COG2733	membrane
CX031_RS09950	COG1012	belongs to the aldehyde dehydrogenase family
CX031_RS09955	COG3284	Transcriptional regulator
CX031_RS09975	COG1380	Effector of murein hydrolase LrgA
CX031_RS09980	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CX031_RS09980	COG4106	trans-aconitate 2-methyltransferase activity
CX031_RS09990	COG0156	8-amino-7-oxononanoate synthase activity
CX031_RS10060	COG1131	(ABC) transporter
CX031_RS10065	COG0842	Transport permease protein
CX031_RS10070	COG0628	permease
CX031_RS10105	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CX031_RS10120	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CX031_RS10125	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CX031_RS10130	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CX031_RS10135	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CX031_RS10140	COG0330	HflC and HflK could
CX031_RS10145	COG0330	HflC and HflK could
CX031_RS10150	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CX031_RS10155	COG1923	regulation of RNA biosynthetic process
CX031_RS10160	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CX031_RS10165	COG1160	GTP binding
CX031_RS10170	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CX031_RS10175	COG2976	Protein conserved in bacteria
CX031_RS10180	COG0124	histidyl-tRNA synthetase
CX031_RS10185	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CX031_RS10195	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CX031_RS10200	COG0105	UTP biosynthetic process
CX031_RS10205	COG0525	valine-tRNA ligase activity
CX031_RS10220	COG0642	Histidine kinase
CX031_RS10245	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CX031_RS10250	COG0336	Belongs to the RNA methyltransferase TrmD family
CX031_RS10255	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CX031_RS10260	COG0228	four-way junction DNA binding
CX031_RS10270	COG0425	Belongs to the sulfur carrier protein TusA family
CX031_RS10275	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CX031_RS10320	COG0154	amidase activity
CX031_RS10325	COG4172	Belongs to the ABC transporter superfamily
CX031_RS10330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CX031_RS10335	COG0601	transmembrane transport
CX031_RS10340	COG0747	negative chemotaxis
CX031_RS10370	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CX031_RS10380	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CX031_RS10400	COG3395	kinase activity
CX031_RS10415	COG1024	Enoyl-CoA hydratase
CX031_RS10435	COG0633	Ferredoxin
CX031_RS10440	COG0443	Heat shock 70 kDa protein
CX031_RS10445	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CX031_RS10450	COG0316	Belongs to the HesB IscA family
CX031_RS10455	COG0822	iron-sulfur transferase activity
CX031_RS10460	COG1104	cysteine desulfurase activity
CX031_RS10470	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CX031_RS10475	COG0556	nucleotide-excision repair
CX031_RS10485	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CX031_RS10515	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CX031_RS10535	COG1028	Short-chain dehydrogenase reductase Sdr
CX031_RS10540	COG0183	Belongs to the thiolase family
CX031_RS10550	COG1024	Enoyl-CoA hydratase
CX031_RS10565	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX031_RS10570	COG0583	DNA-binding transcription factor activity
CX031_RS10575	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CX031_RS10580	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CX031_RS10585	COG0740	serine-type endopeptidase activity
CX031_RS10590	COG0544	peptidyl-prolyl cis-trans isomerase activity
CX031_RS10600	COG1278	Cold shock
CX031_RS10610	COG1278	Cold shock
CX031_RS10645	COG2171	N-acyltransferase activity
CX031_RS10650	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CX031_RS10655	COG2890	protein-(glutamine-N5) methyltransferase activity
CX031_RS10660	COG0488	(ABC) transporter
CX031_RS10665	COG4771	TonB-dependent receptor
CX031_RS10670	COG0210	DNA helicase
CX031_RS10690	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CX031_RS10695	COG0196	riboflavin kinase activity
CX031_RS10700	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CX031_RS10705	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CX031_RS10710	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CX031_RS10720	COG1522	sequence-specific DNA binding
CX031_RS10740	COG2951	lytic endotransglycosylase activity
CX031_RS10745	COG2833	Protein of unknown function (DUF455)
CX031_RS10765	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CX031_RS10765	COG0189	ligase activity
CX031_RS10770	COG1181	Belongs to the D-alanine--D-alanine ligase family
CX031_RS10770	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CX031_RS10775	COG3237	CsbD-like
CX031_RS10785	COG2823	Periplasmic or secreted lipoprotein
CX031_RS10810	COG4181	ATPase activity
CX031_RS10820	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CX031_RS10825	COG0584	glycerophosphoryl diester phosphodiesterase
CX031_RS10830	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CX031_RS10840	COG0678	peroxiredoxin activity
CX031_RS10840	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CX031_RS10850	COG0789	Transcriptional regulator
CX031_RS10855	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CX031_RS10885	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CX031_RS10890	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CX031_RS10900	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CX031_RS10905	COG2252	PERMEase
CX031_RS10915	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CX031_RS10945	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CX031_RS10950	COG2358	TRAP transporter, solute receptor (TAXI family
CX031_RS10985	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CX031_RS10990	COG1366	Belongs to the anti-sigma-factor antagonist family
CX031_RS10995	COG2172	sigma factor antagonist activity
CX031_RS11000	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CX031_RS11010	COG2208	phosphoserine phosphatase activity
CX031_RS11010	COG2770	Histidine kinase
CX031_RS11035	COG1595	DNA-templated transcription, initiation
CX031_RS11050	COG4792	protein secretion
CX031_RS11055	COG4791	protein targeting
CX031_RS11060	COG4794	Type iii secretion
CX031_RS11065	COG4790	Type iii secretion
CX031_RS11100	COG4669	(LipO)protein
CX031_RS11165	COG4789	Type iii secretion
CX031_RS11195	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CX031_RS11200	COG0840	transmembrane signaling receptor activity
CX031_RS11205	COG2233	PERMEase
CX031_RS11230	COG1840	ABC-type Fe3 transport system, periplasmic component
CX031_RS11235	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CX031_RS11240	COG1178	ABC-type Fe3 transport system permease component
CX031_RS11245	COG3842	ATPase activity
CX031_RS11250	COG0583	DNA-binding transcription factor activity
CX031_RS11270	COG0501	Belongs to the peptidase M48B family
CX031_RS11280	COG0697	spore germination
CX031_RS11290	COG1846	Transcriptional regulator
CX031_RS11300	COG1566	PFAM secretion protein HlyD family protein
CX031_RS11305	COG2814	Major facilitator Superfamily
CX031_RS11310	COG0473	3-isopropylmalate dehydrogenase activity
CX031_RS11320	COG0747	negative chemotaxis
CX031_RS11330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CX031_RS11345	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CX031_RS11370	COG1012	belongs to the aldehyde dehydrogenase family
CX031_RS11380	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CX031_RS11385	COG1115	amino acid carrier protein
CX031_RS11390	COG0433	COG0433 Predicted ATPase
CX031_RS11395	COG0217	transcriptional regulatory protein
CX031_RS11400	COG0151	Belongs to the GarS family
CX031_RS11405	COG0408	coproporphyrinogen oxidase activity
CX031_RS11410	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CX031_RS11415	COG0799	negative regulation of ribosome biogenesis
CX031_RS11420	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CX031_RS11425	COG0424	maF-like protein
CX031_RS11430	COG3468	outer membrane autotransporter barrel domain protein
CX031_RS11470	COG1530	ribonuclease E activity
CX031_RS11475	COG0077	Prephenate dehydratase
CX031_RS11490	COG1132	(ABC) transporter
CX031_RS11495	COG0859	PFAM glycosyl transferase family 9
CX031_RS11520	COG2194	sulfuric ester hydrolase activity
CX031_RS11525	COG0438	transferase activity, transferring glycosyl groups
CX031_RS11530	COG0463	Glycosyl transferase, family 2
CX031_RS11535	COG0726	polysaccharide deacetylase
CX031_RS11540	COG0438	transferase activity, transferring glycosyl groups
CX031_RS11555	COG1643	Atp-dependent helicase
CX031_RS11560	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CX031_RS11560	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CX031_RS11565	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CX031_RS11575	COG0704	Plays a role in the regulation of phosphate uptake
CX031_RS11580	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CX031_RS11585	COG1960	acyl-CoA dehydrogenase activity
CX031_RS11610	COG1177	transmembrane transport
CX031_RS11615	COG1176	ABC-type spermidine putrescine transport system, permease component I
CX031_RS11620	COG3842	ATPase activity
CX031_RS11625	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CX031_RS11640	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CX031_RS11645	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CX031_RS11655	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CX031_RS11655	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CX031_RS11670	COG0372	Belongs to the citrate synthase family
CX031_RS11675	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CX031_RS11680	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CX031_RS11685	COG1053	succinate dehydrogenase
CX031_RS11690	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CX031_RS11695	COG2009	succinate dehydrogenase
CX031_RS11700	COG2188	Transcriptional regulator
CX031_RS11705	COG0039	L-malate dehydrogenase activity
CX031_RS11735	COG1981	membrane
CX031_RS11760	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CX031_RS11770	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CX031_RS11800	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CX031_RS11805	COG0148	phosphopyruvate hydratase activity
CX031_RS11815	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CX031_RS11820	COG0504	CTP synthase activity
CX031_RS11845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CX031_RS11855	COG0747	negative chemotaxis
CX031_RS11860	COG4172	Belongs to the ABC transporter superfamily
CX031_RS11865	COG1446	asparaginase
CX031_RS11895	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CX031_RS11910	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CX031_RS11915	COG0697	spore germination
CX031_RS11920	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CX031_RS11930	COG3193	protein, possibly involved in utilization of glycolate and propanediol
CX031_RS11940	COG0791	NLP P60 protein
CX031_RS11955	COG0583	DNA-binding transcription factor activity
CX031_RS11970	COG0583	DNA-binding transcription factor activity
CX031_RS11980	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CX031_RS11995	COG0670	Belongs to the BI1 family
CX031_RS12000	COG3181	Tripartite tricarboxylate transporter family receptor
CX031_RS12015	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CX031_RS12025	COG1381	Involved in DNA repair and RecF pathway recombination
CX031_RS12030	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CX031_RS12035	COG0571	ribonuclease III activity
CX031_RS12040	COG0681	Belongs to the peptidase S26 family
CX031_RS12045	COG0481	GTPase activity
CX031_RS12050	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CX031_RS12075	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CX031_RS12080	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CX031_RS12095	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CX031_RS12100	COG0416	fatty acid biosynthetic process
CX031_RS12105	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CX031_RS12110	COG1399	metal-binding, possibly nucleic acid-binding protein
CX031_RS12115	COG0424	maF-like protein
CX031_RS12125	COG3023	N-Acetylmuramoyl-L-alanine amidase
CX031_RS12140	COG3022	response to hydroperoxide
CX031_RS12155	COG0135	phosphoribosylanthranilate isomerase activity
CX031_RS12170	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CX031_RS12175	COG0101	tRNA pseudouridine synthase activity
CX031_RS12185	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CX031_RS12190	COG0473	3-isopropylmalate dehydrogenase activity
CX031_RS12195	COG0066	3-isopropylmalate dehydratase activity
CX031_RS12200	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CX031_RS12210	COG1122	ATPase activity
CX031_RS12245	COG0243	molybdopterin cofactor binding
CX031_RS12245	COG3383	formate dehydrogenase (NAD+) activity
CX031_RS12275	COG0489	protein tyrosine kinase activity
CX031_RS12280	COG0746	molybdenum cofactor guanylyltransferase activity
CX031_RS12285	COG0303	'Molybdopterin
CX031_RS12290	COG1763	Mo-molybdopterin cofactor biosynthetic process
CX031_RS12300	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CX031_RS12305	COG5001	Diguanylate cyclase
CX031_RS12325	COG3842	ATPase activity
CX031_RS12335	COG0406	alpha-ribazole phosphatase activity
CX031_RS12345	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CX031_RS12350	COG0505	Belongs to the CarA family
CX031_RS12355	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CX031_RS12390	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CX031_RS12395	COG1960	acyl-CoA dehydrogenase activity
CX031_RS12405	COG2867	negative regulation of translational initiation
CX031_RS12415	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CX031_RS12420	COG3706	GGDEF domain
CX031_RS12425	COG0330	HflC and HflK could
CX031_RS12440	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CX031_RS12440	COG0519	Catalyzes the synthesis of GMP from XMP
CX031_RS12450	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CX031_RS12455	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CX031_RS12460	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CX031_RS12465	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CX031_RS12475	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CX031_RS12480	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CX031_RS12485	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CX031_RS12490	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CX031_RS12495	COG0750	zinc metalloprotease
CX031_RS12500	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CX031_RS12510	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CX031_RS12515	COG0233	cytoplasmic translational termination
CX031_RS12520	COG0528	UMP kinase activity
CX031_RS12525	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CX031_RS12530	COG0052	Belongs to the universal ribosomal protein uS2 family
CX031_RS12535	COG0024	Methionine aminopeptidase
CX031_RS12540	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CX031_RS12570	COG0285	dihydrofolate synthase activity
CX031_RS12605	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CX031_RS12615	COG1677	Flagellar hook-basal body complex protein FliE
CX031_RS12625	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CX031_RS12635	COG1157	protein secretion by the type III secretion system
CX031_RS12660	COG1580	Controls the rotational direction of flagella during chemotaxis
CX031_RS12680	COG1338	Plays a role in the flagellum-specific transport system
CX031_RS12700	COG0840	transmembrane signaling receptor activity
CX031_RS12705	COG0840	transmembrane signaling receptor activity
CX031_RS12710	COG0840	transmembrane signaling receptor activity
CX031_RS12720	COG1256	bacterial-type flagellum assembly
CX031_RS12730	COG1706	bacterial-type flagellum-dependent cell motility
CX031_RS12735	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CX031_RS12750	COG1749	Flagellar hook protein flgE
CX031_RS12760	COG1558	bacterial-type flagellum-dependent cell motility
CX031_RS12765	COG1815	bacterial-type flagellum-dependent cell motility
CX031_RS12805	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CX031_RS12810	COG0765	amino acid transport
CX031_RS12815	COG1126	abc transporter atp-binding protein
CX031_RS12830	COG4948	Mandelate Racemase Muconate Lactonizing
CX031_RS12835	COG3181	Tripartite tricarboxylate transporter family receptor
CX031_RS12845	COG0066	3-isopropylmalate dehydratase activity
CX031_RS12860	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX031_RS12870	COG3181	Tripartite tricarboxylate transporter family receptor
CX031_RS12880	COG1802	Transcriptional regulator
CX031_RS12895	COG0583	DNA-binding transcription factor activity
CX031_RS12915	COG1695	Transcriptional regulator
CX031_RS12925	COG3568	Endonuclease Exonuclease Phosphatase
CX031_RS12930	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CX031_RS12980	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CX031_RS12990	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CX031_RS13010	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CX031_RS13040	COG0667	Aldo Keto reductase
CX031_RS13055	COG2259	Doxx family
CX031_RS13085	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX031_RS13105	COG0386	Belongs to the glutathione peroxidase family
CX031_RS13110	COG0625	glutathione transferase activity
CX031_RS13125	COG0095	Lipoate-protein ligase
CX031_RS13140	COG0688	phosphatidylethanolamine metabolic process
CX031_RS13150	COG1464	Belongs to the NlpA lipoprotein family
CX031_RS13165	COG2363	Small membrane protein
CX031_RS13190	COG3842	ATPase activity
CX031_RS13195	COG0395	ABC-type sugar transport system, permease component
CX031_RS13200	COG1175	transmembrane transport
CX031_RS13205	COG1653	transport
CX031_RS13215	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CX031_RS13235	COG0559	Belongs to the binding-protein-dependent transport system permease family
CX031_RS13255	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CX031_RS13280	COG2311	Membrane
CX031_RS13305	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CX031_RS13315	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CX031_RS13320	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CX031_RS13325	COG1760	l-serine dehydratase
CX031_RS13330	COG1283	sodium-dependent phosphate transmembrane transporter activity
CX031_RS13335	COG0412	Dienelactone hydrolase
CX031_RS13350	COG1611	Belongs to the LOG family
CX031_RS13370	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CX031_RS13375	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CX031_RS13380	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CX031_RS13385	COG2251	uridine kinase activity
CX031_RS13385	COG0195	Participates in both transcription termination and antitermination
CX031_RS13390	COG0779	Required for maturation of 30S ribosomal subunits
CX031_RS13395	COG1187	pseudouridine synthase activity
CX031_RS13400	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CX031_RS13410	COG0583	DNA-binding transcription factor activity
CX031_RS13420	COG0523	cobalamin synthesis protein
CX031_RS13440	COG0625	glutathione transferase activity
CX031_RS13445	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CX031_RS13450	COG1047	Peptidyl-prolyl cis-trans
CX031_RS13455	COG2003	Belongs to the UPF0758 family
CX031_RS13460	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CX031_RS13465	COG3483	tryptophan 2,3-dioxygenase activity
CX031_RS13470	COG0254	rRNA binding
CX031_RS13480	COG0534	Mate efflux family protein
CX031_RS13500	COG2304	oxidoreductase activity
CX031_RS13520	COG1028	Short-chain dehydrogenase reductase Sdr
CX031_RS13525	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CX031_RS13530	COG1562	ergosterol biosynthetic process
CX031_RS13535	COG1562	ergosterol biosynthetic process
CX031_RS13540	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CX031_RS13540	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CX031_RS13545	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CX031_RS13555	COG0842	Transport permease protein
CX031_RS13560	COG1131	(ABC) transporter
CX031_RS13580	COG1477	protein flavinylation
CX031_RS13595	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CX031_RS13610	COG5564	TIM-barrel signal transduction protein
CX031_RS13615	COG5441	Belongs to the UPF0261 family
CX031_RS13625	COG3468	outer membrane autotransporter barrel domain protein
CX031_RS13645	COG0542	response to heat
CX031_RS13650	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CX031_RS13665	COG0494	nUDIX hydrolase
CX031_RS13670	COG3530	Putative quorum-sensing-regulated virulence factor
CX031_RS13680	COG1595	DNA-templated transcription, initiation
CX031_RS13685	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CX031_RS13720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CX031_RS13725	COG0765	amino acid transport
CX031_RS13730	COG0765	amino acid transport
CX031_RS13760	COG2988	succinylglutamate desuccinylase activity
CX031_RS13785	COG3181	Tripartite tricarboxylate transporter family receptor
CX031_RS13790	COG2084	Dehydrogenase
CX031_RS13805	COG1619	proteins homologs of microcin C7 resistance protein MccF
CX031_RS13820	COG2814	Major facilitator Superfamily
CX031_RS13830	COG0583	DNA-binding transcription factor activity
CX031_RS13870	COG0672	)-iron permease
CX031_RS13885	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
CX031_RS13890	COG1028	Short-chain dehydrogenase reductase Sdr
CX031_RS13895	COG3243	poly(R)-hydroxyalkanoic acid synthase
CX031_RS13905	COG0564	pseudouridine synthase activity
CX031_RS13915	COG1199	ATP-dependent helicase activity
CX031_RS13920	COG2183	response to ionizing radiation
CX031_RS13925	COG0180	Tryptophanyl-tRNA synthetase
CX031_RS13950	COG3181	Tripartite tricarboxylate transporter family receptor
CX031_RS13960	COG0583	DNA-binding transcription factor activity
CX031_RS13965	COG1028	Short-chain dehydrogenase reductase Sdr
CX031_RS13970	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CX031_RS13975	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CX031_RS13980	COG0508	dehydrogenase complex catalyzes the overall conversion of
CX031_RS13985	COG0567	Dehydrogenase, E1 component
CX031_RS13995	COG1522	sequence-specific DNA binding
CX031_RS14005	COG0281	malic enzyme
CX031_RS14005	COG0280	phosphate acetyltransferase
CX031_RS14010	COG3539	Fimbrial protein
CX031_RS14030	COG0613	PHP domain protein
CX031_RS14040	COG0658	competence protein
CX031_RS14040	COG2333	competence protein COMEC
CX031_RS14065	COG0084	hydrolase, TatD family'
CX031_RS14070	COG1136	(ABC) transporter
CX031_RS14085	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CX031_RS14095	COG1028	Short-chain dehydrogenase reductase Sdr
CX031_RS14100	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CX031_RS14115	COG1022	Amp-dependent synthetase and ligase
CX031_RS14150	COG2205	protein histidine kinase activity
CX031_RS14155	COG0745	RESPONSE REGULATOR receiver
CX031_RS14160	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CX031_RS14170	COG1295	ribonuclease BN
CX031_RS14185	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CX031_RS14215	COG1534	Rna-binding protein
CX031_RS14220	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CX031_RS14225	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CX031_RS14235	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CX031_RS14245	COG0248	Ppx GppA phosphatase
CX031_RS14270	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CX031_RS14285	COG2732	(Barnase) inhibitor
CX031_RS14295	COG0280	phosphate acetyltransferase
CX031_RS14295	COG0281	malic enzyme
CX031_RS14305	COG0436	Aminotransferase
CX031_RS14315	COG0741	lytic transglycosylase activity
CX031_RS14320	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CX031_RS14345	COG1648	precorrin-2 dehydrogenase activity
CX031_RS14345	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CX031_RS14350	COG3468	outer membrane autotransporter barrel domain protein
CX031_RS14360	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CX031_RS14365	COG2027	D-alanyl-D-alanine carboxypeptidase
CX031_RS14370	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CX031_RS14375	COG0343	queuine tRNA-ribosyltransferase activity
CX031_RS14380	COG1862	Preprotein translocase
CX031_RS14385	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CX031_RS14390	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CX031_RS14405	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CX031_RS14410	COG1702	phosphate starvation-inducible protein PhoH
CX031_RS14415	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CX031_RS14420	COG4535	Mg2 and Co2 transporter CorC
CX031_RS14430	COG0667	Aldo Keto reductase
CX031_RS14455	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CX031_RS14460	COG0745	RESPONSE REGULATOR receiver
CX031_RS14465	COG2201	protein-glutamate methylesterase activity
CX031_RS14475	COG0840	transmembrane signaling receptor activity
CX031_RS14490	COG0745	RESPONSE REGULATOR receiver
CX031_RS14525	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CX031_RS14535	COG0739	heme binding
CX031_RS14545	COG0521	Mo-molybdopterin cofactor biosynthetic process
CX031_RS14555	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CX031_RS14585	COG0625	glutathione transferase activity
CX031_RS14600	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CX031_RS14605	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CX031_RS14610	COG0126	phosphoglycerate kinase activity
CX031_RS14615	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CX031_RS14620	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CX031_RS14625	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CX031_RS14635	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CX031_RS14640	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CX031_RS14645	COG0508	dehydrogenase complex catalyzes the overall conversion of
CX031_RS14650	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CX031_RS14660	COG4566	intracellular signal transduction
CX031_RS14665	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CX031_RS14670	COG0339	signal peptide processing
CX031_RS14675	COG1999	signal sequence binding
CX031_RS14705	COG1187	pseudouridine synthase activity
CX031_RS14710	COG3161	chorismate lyase activity
CX031_RS14725	COG0667	Aldo Keto reductase
CX031_RS14740	COG0335	large ribosomal subunit rRNA binding
CX031_RS14775	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CX031_RS14795	COG0450	alkyl hydroperoxide reductase
CX031_RS14800	COG1960	acyl-CoA dehydrogenase activity
CX031_RS14815	COG0123	including yeast histone deacetylase and acetoin utilization protein
CX031_RS14820	COG2951	lytic endotransglycosylase activity
CX031_RS14835	COG1555	photosystem II stabilization
CX031_RS14835	COG1596	polysaccharide export
CX031_RS14840	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CX031_RS14845	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CX031_RS14850	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CX031_RS14870	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CX031_RS14875	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CX031_RS14880	COG0287	Prephenate dehydrogenase
CX031_RS14890	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CX031_RS14905	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CX031_RS14915	COG2814	Major facilitator Superfamily
CX031_RS14950	COG0583	DNA-binding transcription factor activity
CX031_RS14990	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CX031_RS15005	COG0667	Aldo Keto reductase
CX031_RS15015	COG5265	(ABC) transporter
CX031_RS15065	COG0439	Biotin carboxylase
CX031_RS15070	COG2188	Transcriptional regulator
CX031_RS15095	COG0511	ligase activity, forming carbon-carbon bonds
CX031_RS15105	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CX031_RS15125	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CX031_RS15145	COG0500	methyltransferase
CX031_RS15150	COG5265	(ABC) transporter
CX031_RS15165	COG0028	Belongs to the TPP enzyme family
CX031_RS15170	COG0440	acetolactate synthase activity
CX031_RS15175	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CX031_RS15180	COG1183	phosphatidylcholine synthase activity
CX031_RS15195	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CX031_RS15200	COG1185	polyribonucleotide nucleotidyltransferase activity
CX031_RS15215	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CX031_RS15235	COG0149	triose-phosphate isomerase activity
CX031_RS15240	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CX031_RS15250	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CX031_RS15260	COG3799	methylaspartate ammonia-lyase activity
CX031_RS15295	COG0583	DNA-binding transcription factor activity
CX031_RS15300	COG0626	cystathionine gamma-synthase activity
CX031_RS15305	COG3608	succinylglutamate desuccinylase aspartoacylase
CX031_RS15325	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CX031_RS15345	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
CX031_RS15360	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CX031_RS15365	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CX031_RS15370	COG1733	regulation of RNA biosynthetic process
CX031_RS15380	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CX031_RS15385	COG0583	DNA-binding transcription factor activity
CX031_RS15390	COG1597	lipid kinase activity
CX031_RS15400	COG0671	phosphoesterase, PA-phosphatase related
CX031_RS15430	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CX031_RS15435	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CX031_RS15440	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CX031_RS15445	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CX031_RS15450	COG0649	NAD binding
CX031_RS15455	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CX031_RS15465	COG1034	ATP synthesis coupled electron transport
CX031_RS15470	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CX031_RS15475	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CX031_RS15485	COG0713	ATP synthesis coupled electron transport
CX031_RS15500	COG1007	ATP synthesis coupled electron transport
CX031_RS15510	COG4774	siderophore transport
CX031_RS15515	COG4774	siderophore transport
CX031_RS15530	COG0028	Belongs to the TPP enzyme family
CX031_RS15535	COG3181	Tripartite tricarboxylate transporter family receptor
CX031_RS15540	COG0583	DNA-binding transcription factor activity
CX031_RS15545	COG0560	Phosphoserine phosphatase
CX031_RS15550	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CX031_RS15555	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CX031_RS15560	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CX031_RS15575	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CX031_RS15580	COG0308	aminopeptidase N
CX031_RS15600	COG0028	Belongs to the TPP enzyme family
CX031_RS15620	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CX031_RS15630	COG0318	PFAM AMP-dependent synthetase and ligase
CX031_RS15640	COG1802	Transcriptional regulator
CX031_RS15650	COG1802	Transcriptional regulator
CX031_RS15660	COG1028	Short-chain dehydrogenase reductase Sdr
CX031_RS15680	COG1126	abc transporter atp-binding protein
CX031_RS15685	COG0765	amino acid transport
CX031_RS15705	COG1538	Outer membrane efflux protein
CX031_RS15710	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CX031_RS15715	COG2274	protein secretion by the type I secretion system
CX031_RS15720	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CX031_RS15730	COG2994	toxin metabolic process
CX031_RS15750	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CX031_RS15755	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
CX031_RS15765	COG0583	DNA-binding transcription factor activity
CX031_RS15775	COG0142	geranyltranstransferase activity
CX031_RS15785	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CX031_RS15790	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CX031_RS15795	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CX031_RS15800	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CX031_RS15845	COG3712	iron ion homeostasis
CX031_RS15850	COG4774	siderophore transport
CX031_RS15855	COG2353	YceI-like domain
CX031_RS15870	COG0019	diaminopimelate decarboxylase activity
CX031_RS15890	COG0747	negative chemotaxis
CX031_RS15895	COG0601	transmembrane transport
CX031_RS15900	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CX031_RS15910	COG0154	amidase activity
CX031_RS15915	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CX031_RS15940	COG2154	pterin-4-alpha-carbinolamine dehydratase
CX031_RS15950	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CX031_RS15960	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CX031_RS15965	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CX031_RS15970	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CX031_RS15975	COG1929	Belongs to the glycerate kinase type-1 family
CX031_RS15980	COG0469	pyruvate kinase activity
CX031_RS15985	COG0700	Nucleoside recognition
CX031_RS16020	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CX031_RS16025	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CX031_RS16040	COG0823	Involved in the tonB-independent uptake of proteins
CX031_RS16050	COG0848	biopolymer transport protein
CX031_RS16055	COG0811	peptide transport
CX031_RS16060	COG0824	Thioesterase
CX031_RS16065	COG0442	prolyl-tRNA aminoacylation
CX031_RS16070	COG0494	nUDIX hydrolase
CX031_RS16085	COG2135	peptidase activity
CX031_RS16160	COG1196	nuclear chromosome segregation
CX031_RS16300	COG1464	Belongs to the NlpA lipoprotein family
CX031_RS16330	COG4211	Belongs to the binding-protein-dependent transport system permease family
CX031_RS16340	COG0154	amidase activity
CX031_RS16345	COG0288	reversible hydration of carbon dioxide
CX031_RS16360	COG0514	ATP-dependent DNA helicase (RecQ)
CX031_RS16365	COG2255	four-way junction helicase activity
CX031_RS16380	COG0632	four-way junction helicase activity
CX031_RS16385	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CX031_RS16405	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CX031_RS16415	COG0006	proline dipeptidase activity
CX031_RS16440	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CX031_RS16455	COG4783	chaperone-mediated protein folding
CX031_RS16460	COG0429	hydrolase of the alpha beta-hydrolase fold
CX031_RS16490	COG0513	Belongs to the DEAD box helicase family
CX031_RS16510	COG1546	Belongs to the CinA family
CX031_RS16510	COG1058	Belongs to the CinA family
CX031_RS16515	COG1414	Transcriptional regulator
CX031_RS16535	COG0167	dihydroorotate dehydrogenase activity
CX031_RS16540	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CX031_RS16555	COG0583	DNA-binding transcription factor activity
CX031_RS16615	COG0280	phosphate acetyltransferase
CX031_RS16615	COG0281	malic enzyme
CX031_RS16625	COG0601	transmembrane transport
CX031_RS16630	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CX031_RS16635	COG4172	Belongs to the ABC transporter superfamily
CX031_RS16665	COG0640	Transcriptional regulator
CX031_RS16680	COG3135	benzoate transporter
CX031_RS16685	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CX031_RS16690	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CX031_RS16695	COG0742	ribosomal rna small subunit methyltransferase
CX031_RS16710	COG3639	organic phosphonate transmembrane transporter activity
CX031_RS16715	COG3639	organic phosphonate transmembrane transporter activity
CX031_RS16755	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CX031_RS16760	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CX031_RS16770	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CX031_RS16775	COG1546	Belongs to the CinA family
CX031_RS16775	COG1058	Belongs to the CinA family
CX031_RS16780	COG0284	orotidine-5'-phosphate decarboxylase activity
CX031_RS16785	COG1252	NADH dehydrogenase
CX031_RS16800	COG3468	outer membrane autotransporter barrel domain protein
CX031_RS16805	COG0459	protein refolding
CX031_RS16810	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CX031_RS16830	COG1053	succinate dehydrogenase
CX031_RS16845	COG0583	DNA-binding transcription factor activity
CX031_RS16850	COG1053	succinate dehydrogenase
CX031_RS16875	COG3706	GGDEF domain
CX031_RS16915	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
CX031_RS16925	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CX031_RS16935	COG0069	glutamate synthase activity
CX031_RS16940	COG2391	methyltransferase activity
CX031_RS16945	COG0679	Auxin Efflux Carrier
CX031_RS16970	COG0557	exoribonuclease II activity
CX031_RS16975	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CX031_RS16985	COG3128	pkhd-type hydroxylase
CX031_RS16990	COG0776	regulation of translation
CX031_RS17020	COG0642	Histidine kinase
CX031_RS17025	COG3158	transport of potassium into the cell
CX031_RS17030	COG0137	argininosuccinate synthase activity
CX031_RS17035	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CX031_RS17040	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CX031_RS17050	COG0583	DNA-binding transcription factor activity
CX031_RS17060	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CX031_RS17080	COG2186	Transcriptional regulator
CX031_RS17090	COG2223	nitrite transmembrane transporter activity
CX031_RS17100	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CX031_RS17105	COG0450	alkyl hydroperoxide reductase
CX031_RS17125	COG1214	PFAM Peptidase M22, glycoprotease
CX031_RS17130	COG1573	uracil-dna glycosylase
CX031_RS17135	COG0477	Major facilitator Superfamily
CX031_RS17140	COG1196	nuclear chromosome segregation
CX031_RS17150	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CX031_RS17155	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CX031_RS17170	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CX031_RS17175	COG1122	ATPase activity
CX031_RS17180	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CX031_RS17185	COG1268	BioY protein
CX031_RS17205	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CX031_RS17240	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CX031_RS17245	COG2878	Part of a membrane complex involved in electron transport
CX031_RS17260	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CX031_RS17265	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CX031_RS17270	COG0251	oxidation-reduction process
CX031_RS17280	COG3228	Belongs to the MtfA family
CX031_RS17285	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CX031_RS17295	COG0133	tryptophan synthase activity
CX031_RS17300	COG0159	tryptophan synthase activity
CX031_RS17305	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CX031_RS17325	COG1530	ribonuclease E activity
CX031_RS17335	COG0546	phosphoglycolate phosphatase activity
CX031_RS17340	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CX031_RS17345	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CX031_RS17360	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX031_RS17365	COG0583	DNA-binding transcription factor activity
CX031_RS17375	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX031_RS17395	COG0251	oxidation-reduction process
CX031_RS17400	COG1017	nitric oxide dioxygenase activity
CX031_RS17400	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CX031_RS17405	COG2031	fatty acid transporter
CX031_RS17410	COG1012	belongs to the aldehyde dehydrogenase family
CX031_RS17415	COG1802	Transcriptional regulator
CX031_RS17425	COG1278	Cold shock
CX031_RS17430	COG0583	DNA-binding transcription factor activity
CX031_RS17455	COG0183	Belongs to the thiolase family
CX031_RS17465	COG1960	acyl-CoA dehydrogenase activity
CX031_RS17470	COG0583	DNA-binding transcription factor activity
CX031_RS17475	COG3181	Tripartite tricarboxylate transporter family receptor
CX031_RS17480	COG1024	Enoyl-CoA hydratase
CX031_RS17485	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX031_RS17490	COG1253	flavin adenine dinucleotide binding
CX031_RS17495	COG1285	pathogenesis
CX031_RS17505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CX031_RS17520	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CX031_RS17530	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CX031_RS17540	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX031_RS17545	COG3181	Tripartite tricarboxylate transporter family receptor
CX031_RS17550	COG1960	acyl-CoA dehydrogenase activity
CX031_RS17570	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CX031_RS17575	COG1024	Enoyl-CoA hydratase
CX031_RS17580	COG1960	acyl-CoA dehydrogenase activity
CX031_RS17600	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CX031_RS17605	COG0022	dehydrogenase e1 component
CX031_RS17610	COG1024	Enoyl-CoA hydratase
CX031_RS17615	COG0508	dehydrogenase complex catalyzes the overall conversion of
CX031_RS17635	COG0683	leucine binding
CX031_RS17640	COG0559	Belongs to the binding-protein-dependent transport system permease family
CX031_RS17645	COG0411	ABC transporter
CX031_RS17655	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CX031_RS17670	COG3181	Tripartite tricarboxylate transporter family receptor
CX031_RS17700	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CX031_RS17705	COG0793	Belongs to the peptidase S41A family
CX031_RS17710	COG4942	peptidase
CX031_RS17715	COG0588	phosphoglycerate mutase activity
CX031_RS17720	COG1054	Belongs to the UPF0176 family
CX031_RS17725	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CX031_RS17730	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CX031_RS17735	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CX031_RS17740	COG3181	Tripartite tricarboxylate transporter family receptor
CX031_RS17755	COG2226	methyltransferase
CX031_RS17760	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CX031_RS17775	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CX031_RS17780	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CX031_RS17805	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CX031_RS17830	COG1335	isochorismatase
CX031_RS17835	COG2309	aminopeptidase activity
CX031_RS17845	COG3473	Maleate cis-trans isomerase
CX031_RS17855	COG2068	MobA-Related Protein
CX031_RS17880	COG2204	response regulator
CX031_RS17885	COG5000	phosphorelay sensor kinase activity
CX031_RS17895	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CX031_RS17895	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CX031_RS17905	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
CX031_RS17940	COG0583	DNA-binding transcription factor activity
CX031_RS17960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CX031_RS17965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CX031_RS17980	COG0758	DNA mediated transformation
CX031_RS17985	COG1522	sequence-specific DNA binding
CX031_RS17995	COG0242	peptide deformylase activity
CX031_RS18010	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CX031_RS18020	COG0546	phosphoglycolate phosphatase activity
CX031_RS18040	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CX031_RS18045	COG1942	4-Oxalocrotonate Tautomerase
CX031_RS18050	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CX031_RS18075	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CX031_RS18095	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CX031_RS18100	COG1024	Enoyl-CoA hydratase
CX031_RS18105	COG1414	Transcriptional regulator
CX031_RS18110	COG0318	PFAM AMP-dependent synthetase and ligase
CX031_RS18115	COG3181	Tripartite tricarboxylate transporter family receptor
CX031_RS18160	COG3422	double-strand break repair
CX031_RS18165	COG0330	HflC and HflK could
CX031_RS18175	COG0251	oxidation-reduction process
CX031_RS18225	COG3723	Recombinational DNA repair protein, rece pathway
CX031_RS18260	COG0582	viral genome integration into host DNA
CX031_RS18295	COG0706	membrane insertase activity
CX031_RS18300	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CX031_RS18305	COG0594	ribonuclease P activity
CX031_RS18310	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CX031_RS18315	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CX031_RS18330	COG1414	Transcriptional regulator
CX031_RS18335	COG0154	amidase activity
CX031_RS18350	COG1304	FMN binding
CX031_RS18400	COG0183	Belongs to the thiolase family
CX031_RS18405	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CX031_RS18420	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CX031_RS18425	COG3181	Tripartite tricarboxylate transporter family receptor
CX031_RS18435	COG2358	TRAP transporter, solute receptor (TAXI family
CX031_RS18445	COG1629	transport
CX031_RS18450	COG2922	Belongs to the Smg family
CX031_RS18475	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CX031_RS18480	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CX031_RS18485	COG1028	Short-chain dehydrogenase reductase Sdr
CX031_RS18490	COG1012	belongs to the aldehyde dehydrogenase family
CX031_RS18500	COG0028	Belongs to the TPP enzyme family
CX031_RS18505	COG1522	sequence-specific DNA binding
CX031_RS18510	COG3781	membrane
CX031_RS18520	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CX031_RS18540	COG4206	TonB-dependent receptor
CX031_RS18545	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CX031_RS18550	COG2022	thiamine diphosphate biosynthetic process
CX031_RS18555	COG0351	phosphomethylpyrimidine kinase
CX031_RS18560	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CX031_RS18575	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CX031_RS18585	COG0628	permease
CX031_RS18595	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CX031_RS18610	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CX031_RS18615	COG0049	tRNA binding
CX031_RS18620	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CX031_RS18625	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CX031_RS18630	COG0051	transcription antitermination factor activity, RNA binding
CX031_RS18635	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CX031_RS18640	COG0088	Forms part of the polypeptide exit tunnel
CX031_RS18645	COG0089	rRNA binding
CX031_RS18650	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CX031_RS18655	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CX031_RS18660	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CX031_RS18665	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CX031_RS18670	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CX031_RS18675	COG0255	Belongs to the universal ribosomal protein uL29 family
CX031_RS18680	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CX031_RS18700	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CX031_RS18705	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CX031_RS18710	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CX031_RS18715	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CX031_RS18720	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CX031_RS18725	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CX031_RS18730	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CX031_RS18735	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CX031_RS18740	COG1841	ribosomal large subunit assembly
CX031_RS18745	COG0200	Binds to the 23S rRNA
CX031_RS18750	COG0201	protein transport
CX031_RS18755	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CX031_RS18760	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CX031_RS18765	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CX031_RS18770	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CX031_RS18775	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CX031_RS18780	COG0202	RNA polymerase activity
CX031_RS18785	COG0203	ribosomal protein L17
CX031_RS18790	COG0537	adenosine 5'-monophosphoramidase activity
CX031_RS18795	COG1324	tolerance protein
CX031_RS18800	COG4232	protein-disulfide reductase activity
CX031_RS18815	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CX031_RS18825	COG1333	cytochrome c biogenesis protein
CX031_RS18830	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CX031_RS18845	COG1965	Belongs to the frataxin family
CX031_RS18855	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CX031_RS18860	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CX031_RS18865	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CX031_RS18880	COG2814	Major facilitator Superfamily
CX031_RS18885	COG0629	single-stranded DNA binding
CX031_RS18925	COG0402	S-adenosylhomocysteine deaminase activity
CX031_RS18935	COG0438	transferase activity, transferring glycosyl groups
CX031_RS18955	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CX031_RS18980	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CX031_RS19005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CX031_RS19010	COG1956	GAF domain-containing protein
CX031_RS19015	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CX031_RS19030	COG1652	LysM domain
CX031_RS19045	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CX031_RS19060	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CX031_RS19090	COG3181	Tripartite tricarboxylate transporter family receptor
CX031_RS19105	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CX031_RS19120	COG1024	Enoyl-CoA hydratase
CX031_RS19135	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX031_RS19140	COG1309	transcriptional regulator
CX031_RS19145	COG2816	NAD+ diphosphatase activity
CX031_RS19150	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CX031_RS19235	COG2814	Major facilitator Superfamily
CX031_RS19240	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CX031_RS19260	COG1999	signal sequence binding
CX031_RS19265	COG0109	protoheme IX farnesyltransferase activity
CX031_RS19305	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CX031_RS19325	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CX031_RS19330	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CX031_RS19340	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CX031_RS19345	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CX031_RS19355	COG0067	glutamate synthase
CX031_RS19355	COG0069	glutamate synthase activity
CX031_RS19355	COG0070	glutamate synthase
CX031_RS19365	COG3047	cAMP biosynthetic process
CX031_RS19375	COG1127	ABC transporter
CX031_RS19380	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CX031_RS19385	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CX031_RS19390	COG2853	Lipoprotein
CX031_RS19405	COG0842	Transport permease protein
CX031_RS19415	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CX031_RS19420	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CX031_RS19425	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CX031_RS19430	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CX031_RS19435	COG0131	Imidazoleglycerol-phosphate dehydratase
CX031_RS19440	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CX031_RS19445	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CX031_RS19450	COG0107	imidazoleglycerol-phosphate synthase activity
CX031_RS19455	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CX031_RS19460	COG0140	phosphoribosyl-ATP diphosphatase activity
CX031_RS19465	COG0537	adenosine 5'-monophosphoramidase activity
CX031_RS19470	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CX031_RS19475	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CX031_RS19490	COG3181	Tripartite tricarboxylate transporter family receptor
CX031_RS19525	COG3702	type iv secretory pathway
CX031_RS19530	COG3451	type IV secretory pathway VirB4
CX031_RS19545	COG3736	Type IV secretory pathway, component VirB8
CX031_RS19550	COG3504	Conjugal transfer protein
CX031_RS19555	COG2948	multi-organism process
CX031_RS19560	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
CX031_RS19570	COG0697	spore germination
CX031_RS19590	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CX031_RS19595	COG0747	negative chemotaxis
CX031_RS19600	COG0601	transmembrane transport
CX031_RS19605	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CX031_RS19620	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CX031_RS19630	COG0494	nUDIX hydrolase
CX031_RS19675	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
CX031_RS19680	COG0237	dephospho-CoA kinase activity
CX031_RS19685	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CX031_RS19700	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CX031_RS19705	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CX031_RS19715	COG0477	Major facilitator Superfamily
CX031_RS19720	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CX031_RS19735	COG1126	abc transporter atp-binding protein
CX031_RS19740	COG0765	amino acid transport
CX031_RS19745	COG4597	amino acid ABC transporter
CX031_RS19750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CX031_RS19755	COG2884	Cell division ATP-binding protein ftsE
CX031_RS19760	COG2177	Part of the ABC transporter FtsEX involved in
CX031_RS19765	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CX031_RS19775	COG1194	a g-specific adenine glycosylase
CX031_RS19785	COG2226	methyltransferase
CX031_RS19795	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX031_RS19800	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX031_RS19815	COG1024	Enoyl-CoA hydratase
CX031_RS19835	COG1024	Enoyl-CoA hydratase
CX031_RS19840	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX031_RS19855	COG0753	catalase activity
CX031_RS19860	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CX031_RS19865	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CX031_RS19875	COG2175	clavaminate synthase activity
CX031_RS19880	COG1473	amidohydrolase
CX031_RS19885	COG4608	Belongs to the ABC transporter superfamily
CX031_RS19890	COG0444	Belongs to the ABC transporter superfamily
CX031_RS19905	COG0747	negative chemotaxis
CX031_RS19910	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CX031_RS19945	COG0436	Aminotransferase
CX031_RS19950	COG1278	Cold shock