locus-tag	class	description
WU11_RS00005	COG0445	tRNA wobble uridine modification
WU11_RS00010	COG0357	Ribosomal RNA small subunit methyltransferase G
WU11_RS00015	COG1192	Involved in chromosome partitioning
WU11_RS00025	COG1475	DNA binding
WU11_RS00030	COG0252	asparaginase activity
WU11_RS00055	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
WU11_RS00065	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
WU11_RS00075	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
WU11_RS00080	COG0081	regulation of translation
WU11_RS00085	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
WU11_RS00090	COG0222	ribosome binding
WU11_RS00095	COG0085	RNA polymerase activity
WU11_RS00100	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
WU11_RS00140	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU11_RS00165	COG1024	Enoyl-CoA hydratase
WU11_RS00185	COG0752	glycyl-tRNA synthetase alpha subunit
WU11_RS00190	COG0751	glycine-tRNA ligase activity
WU11_RS00195	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
WU11_RS00200	COG0204	Acyl-transferase
WU11_RS00215	COG0242	peptide deformylase activity
WU11_RS00250	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
WU11_RS00255	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
WU11_RS00260	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
WU11_RS00260	COG2813	Specifically methylates the guanine in position
WU11_RS00275	COG2223	nitrite transmembrane transporter activity
WU11_RS00285	COG1794	racemase activity, acting on amino acids and derivatives
WU11_RS00290	COG1126	abc transporter atp-binding protein
WU11_RS00295	COG0765	amino acid transport
WU11_RS00300	COG0765	amino acid transport
WU11_RS00305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WU11_RS00370	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
WU11_RS00400	COG0326	Molecular chaperone. Has ATPase activity
WU11_RS00405	COG0625	glutathione transferase activity
WU11_RS00420	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
WU11_RS00425	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
WU11_RS00455	COG0438	transferase activity, transferring glycosyl groups
WU11_RS00460	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
WU11_RS00465	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
WU11_RS00495	COG0859	PFAM glycosyl transferase family 9
WU11_RS00510	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
WU11_RS00520	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
WU11_RS00525	COG1127	ABC transporter
WU11_RS00545	COG1686	Belongs to the peptidase S11 family
WU11_RS00555	COG2921	Belongs to the UPF0250 family
WU11_RS00560	COG0321	lipoyl(octanoyl) transferase activity
WU11_RS00565	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
WU11_RS00600	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
WU11_RS00610	COG0018	arginyl-trna synthetase
WU11_RS00630	COG0395	ABC-type sugar transport system, permease component
WU11_RS00635	COG1175	transmembrane transport
WU11_RS00640	COG1653	transport
WU11_RS00645	COG3842	ATPase activity
WU11_RS00650	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
WU11_RS00660	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
WU11_RS00680	COG1609	Transcriptional regulator
WU11_RS00690	COG0154	amidase activity
WU11_RS00695	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
WU11_RS00705	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
WU11_RS00715	COG0583	DNA-binding transcription factor activity
WU11_RS00730	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WU11_RS00735	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
WU11_RS00750	COG1802	Transcriptional regulator
WU11_RS00765	COG1024	Enoyl-CoA hydratase
WU11_RS00775	COG3181	Tripartite tricarboxylate transporter family receptor
WU11_RS00790	COG1984	allophanate hydrolase subunit 2
WU11_RS00795	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
WU11_RS00805	COG0583	DNA-binding transcription factor activity
WU11_RS00810	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
WU11_RS00820	COG5002	protein histidine kinase activity
WU11_RS00830	COG5002	protein histidine kinase activity
WU11_RS00835	COG0745	RESPONSE REGULATOR receiver
WU11_RS00845	COG0745	RESPONSE REGULATOR receiver
WU11_RS00850	COG2226	methyltransferase
WU11_RS00865	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
WU11_RS00885	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
WU11_RS00895	COG0513	Belongs to the DEAD box helicase family
WU11_RS00900	COG1280	lysine exporter protein (LysE YggA)
WU11_RS00905	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
WU11_RS00940	COG1054	Belongs to the UPF0176 family
WU11_RS00945	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WU11_RS00945	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WU11_RS00955	COG0489	protein tyrosine kinase activity
WU11_RS00970	COG0717	Belongs to the dCTP deaminase family
WU11_RS01000	COG2081	HI0933 family
WU11_RS01010	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
WU11_RS01020	COG0404	The glycine cleavage system catalyzes the degradation of glycine
WU11_RS01025	COG0509	glycine decarboxylation via glycine cleavage system
WU11_RS01030	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
WU11_RS01030	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
WU11_RS01070	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
WU11_RS01085	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
WU11_RS01095	COG1414	Transcriptional regulator
WU11_RS01100	COG1028	Short-chain dehydrogenase reductase Sdr
WU11_RS01105	COG2031	fatty acid transporter
WU11_RS01110	COG1250	3-hydroxyacyl-CoA dehydrogenase
WU11_RS01120	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
WU11_RS01125	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
WU11_RS01135	COG4257	antibiotic catabolic process
WU11_RS01160	COG1012	belongs to the aldehyde dehydrogenase family
WU11_RS01165	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
WU11_RS01170	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WU11_RS01195	COG1028	Short-chain dehydrogenase reductase Sdr
WU11_RS01205	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WU11_RS01220	COG2188	Transcriptional regulator
WU11_RS01225	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
WU11_RS01250	COG0617	tRNA 3'-terminal CCA addition
WU11_RS01265	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
WU11_RS01270	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
WU11_RS01275	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
WU11_RS01280	COG0586	Pfam SNARE associated Golgi protein
WU11_RS01285	COG0860	N-Acetylmuramoyl-L-alanine amidase
WU11_RS01290	COG0802	atpase or kinase
WU11_RS01295	COG0114	fumarate hydratase activity
WU11_RS01305	COG3181	Tripartite tricarboxylate transporter family receptor
WU11_RS01315	COG0405	Gamma-glutamyltransferase
WU11_RS01320	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU11_RS01330	COG1960	acyl-CoA dehydrogenase activity
WU11_RS01355	COG1294	oxidase, subunit
WU11_RS01365	COG4988	ABC transporter
WU11_RS01370	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
WU11_RS01375	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
WU11_RS01390	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WU11_RS01420	COG2969	positive regulation of protein catabolic process
WU11_RS01425	COG0625	glutathione transferase activity
WU11_RS01430	COG2857	Cytochrome c1
WU11_RS01435	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
WU11_RS01440	COG0723	plastoquinol--plastocyanin reductase activity
WU11_RS01445	COG1970	mechanosensitive ion channel activity
WU11_RS01450	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
WU11_RS01465	COG2808	Putative FMN-binding domain
WU11_RS01470	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
WU11_RS01475	COG0747	negative chemotaxis
WU11_RS01480	COG0657	acetylesterase activity
WU11_RS01490	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
WU11_RS01495	COG2207	Transcriptional regulator
WU11_RS01500	COG0129	dihydroxy-acid dehydratase activity
WU11_RS01505	COG2814	Major facilitator Superfamily
WU11_RS01510	COG0583	DNA-binding transcription factor activity
WU11_RS01520	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
WU11_RS01590	COG1024	Enoyl-CoA hydratase
WU11_RS01595	COG1960	acyl-CoA dehydrogenase activity
WU11_RS01620	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
WU11_RS01625	COG0352	thiamine-phosphate diphosphorylase activity
WU11_RS01640	COG1678	Uncharacterized ACR, COG1678
WU11_RS01645	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
WU11_RS01650	COG0540	Belongs to the ATCase OTCase family
WU11_RS01665	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
WU11_RS01675	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
WU11_RS01710	COG1234	tRNA 3'-trailer cleavage
WU11_RS01730	COG3064	Membrane
WU11_RS01760	COG1683	Conserved Protein
WU11_RS01765	COG1120	ATPase activity
WU11_RS01770	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WU11_RS01775	COG4558	Periplasmic binding protein
WU11_RS01780	COG3720	iron ion transport
WU11_RS01790	COG3712	iron ion homeostasis
WU11_RS01795	COG1595	DNA-templated transcription, initiation
WU11_RS01830	COG1802	Transcriptional regulator
WU11_RS01840	COG3069	C4-dicarboxylate transmembrane transporter activity
WU11_RS01850	COG1012	belongs to the aldehyde dehydrogenase family
WU11_RS01885	COG2860	membrane
WU11_RS01890	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
WU11_RS01895	COG0708	Exodeoxyribonuclease III
WU11_RS01900	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
WU11_RS01905	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
WU11_RS01910	COG0154	amidase activity
WU11_RS01915	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
WU11_RS01920	COG1077	Cell shape determining protein MreB Mrl
WU11_RS01925	COG1792	Involved in formation and maintenance of cell shape
WU11_RS01935	COG0768	penicillin binding
WU11_RS01940	COG0772	Belongs to the SEDS family
WU11_RS01945	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
WU11_RS01950	COG0471	metal ion transport
WU11_RS01955	COG1309	transcriptional regulator
WU11_RS01965	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
WU11_RS01980	COG2823	Periplasmic or secreted lipoprotein
WU11_RS01985	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
WU11_RS02000	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
WU11_RS02020	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU11_RS02030	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU11_RS02050	COG0492	ferredoxin-NADP+ reductase activity
WU11_RS02060	COG3181	Tripartite tricarboxylate transporter family receptor
WU11_RS02065	COG1024	Enoyl-CoA hydratase
WU11_RS02065	COG1250	3-hydroxyacyl-CoA dehydrogenase
WU11_RS02070	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU11_RS02075	COG0028	Belongs to the TPP enzyme family
WU11_RS02100	COG3181	Tripartite tricarboxylate transporter family receptor
WU11_RS02110	COG0697	spore germination
WU11_RS02140	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
WU11_RS02145	COG0463	Glycosyl transferase, family 2
WU11_RS02165	COG0786	glutamate:sodium symporter activity
WU11_RS02175	COG2031	fatty acid transporter
WU11_RS02190	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
WU11_RS02195	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WU11_RS02205	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
WU11_RS02220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WU11_RS02230	COG1285	pathogenesis
WU11_RS02235	COG1253	flavin adenine dinucleotide binding
WU11_RS02240	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU11_RS02245	COG1024	Enoyl-CoA hydratase
WU11_RS02250	COG3181	Tripartite tricarboxylate transporter family receptor
WU11_RS02255	COG0583	DNA-binding transcription factor activity
WU11_RS02260	COG1960	acyl-CoA dehydrogenase activity
WU11_RS02270	COG0183	Belongs to the thiolase family
WU11_RS02290	COG0583	DNA-binding transcription factor activity
WU11_RS02295	COG1278	Cold shock
WU11_RS02305	COG1802	Transcriptional regulator
WU11_RS02310	COG1012	belongs to the aldehyde dehydrogenase family
WU11_RS02315	COG2031	fatty acid transporter
WU11_RS02320	COG1017	nitric oxide dioxygenase activity
WU11_RS02320	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WU11_RS02325	COG0251	oxidation-reduction process
WU11_RS02345	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU11_RS02355	COG0583	DNA-binding transcription factor activity
WU11_RS02360	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU11_RS02370	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
WU11_RS02375	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
WU11_RS02380	COG0546	phosphoglycolate phosphatase activity
WU11_RS02390	COG1530	ribonuclease E activity
WU11_RS02405	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
WU11_RS02410	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
WU11_RS02415	COG0159	tryptophan synthase activity
WU11_RS02420	COG0133	tryptophan synthase activity
WU11_RS02430	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
WU11_RS02435	COG3228	Belongs to the MtfA family
WU11_RS02445	COG0251	oxidation-reduction process
WU11_RS02450	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
WU11_RS02455	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
WU11_RS02470	COG2878	Part of a membrane complex involved in electron transport
WU11_RS02475	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
WU11_RS02510	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
WU11_RS02530	COG1268	BioY protein
WU11_RS02535	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
WU11_RS02540	COG1122	ATPase activity
WU11_RS02545	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
WU11_RS02560	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
WU11_RS02565	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
WU11_RS02575	COG1196	nuclear chromosome segregation
WU11_RS02580	COG0477	Major facilitator Superfamily
WU11_RS02585	COG1573	uracil-dna glycosylase
WU11_RS02590	COG1214	PFAM Peptidase M22, glycoprotease
WU11_RS02615	COG0450	alkyl hydroperoxide reductase
WU11_RS02620	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WU11_RS02630	COG2223	nitrite transmembrane transporter activity
WU11_RS02640	COG2186	Transcriptional regulator
WU11_RS02660	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
WU11_RS02670	COG0583	DNA-binding transcription factor activity
WU11_RS02680	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
WU11_RS02685	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
WU11_RS02690	COG0137	argininosuccinate synthase activity
WU11_RS02695	COG3158	transport of potassium into the cell
WU11_RS02700	COG0642	Histidine kinase
WU11_RS02730	COG0776	regulation of translation
WU11_RS02735	COG3128	pkhd-type hydroxylase
WU11_RS02745	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
WU11_RS02750	COG0557	exoribonuclease II activity
WU11_RS02775	COG0679	Auxin Efflux Carrier
WU11_RS02780	COG2391	methyltransferase activity
WU11_RS02785	COG0069	glutamate synthase activity
WU11_RS02795	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WU11_RS02805	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
WU11_RS02810	COG1262	PFAM Formylglycine-generating sulfatase enzyme
WU11_RS02845	COG3706	GGDEF domain
WU11_RS02865	COG1053	succinate dehydrogenase
WU11_RS02870	COG0583	DNA-binding transcription factor activity
WU11_RS02880	COG1053	succinate dehydrogenase
WU11_RS02900	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
WU11_RS02905	COG0459	protein refolding
WU11_RS02910	COG3468	outer membrane autotransporter barrel domain protein
WU11_RS02925	COG1252	NADH dehydrogenase
WU11_RS02930	COG0284	orotidine-5'-phosphate decarboxylase activity
WU11_RS02935	COG1546	Belongs to the CinA family
WU11_RS02935	COG1058	Belongs to the CinA family
WU11_RS02940	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
WU11_RS02950	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
WU11_RS02955	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
WU11_RS02990	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
WU11_RS02995	COG3639	organic phosphonate transmembrane transporter activity
WU11_RS03000	COG3639	organic phosphonate transmembrane transporter activity
WU11_RS03020	COG0742	ribosomal rna small subunit methyltransferase
WU11_RS03025	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
WU11_RS03030	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
WU11_RS03035	COG3135	benzoate transporter
WU11_RS03050	COG0640	Transcriptional regulator
WU11_RS03080	COG4172	Belongs to the ABC transporter superfamily
WU11_RS03085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WU11_RS03090	COG0601	transmembrane transport
WU11_RS03100	COG0280	phosphate acetyltransferase
WU11_RS03100	COG0281	malic enzyme
WU11_RS03160	COG0583	DNA-binding transcription factor activity
WU11_RS03170	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
WU11_RS03175	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
WU11_RS03180	COG0167	dihydroorotate dehydrogenase activity
WU11_RS03200	COG1414	Transcriptional regulator
WU11_RS03205	COG1058	Belongs to the CinA family
WU11_RS03205	COG1546	Belongs to the CinA family
WU11_RS03225	COG0513	Belongs to the DEAD box helicase family
WU11_RS03255	COG0429	hydrolase of the alpha beta-hydrolase fold
WU11_RS03260	COG4783	chaperone-mediated protein folding
WU11_RS03275	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WU11_RS03300	COG0006	proline dipeptidase activity
WU11_RS03310	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WU11_RS03330	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
WU11_RS03335	COG0632	four-way junction helicase activity
WU11_RS03350	COG2255	four-way junction helicase activity
WU11_RS03355	COG0514	ATP-dependent DNA helicase (RecQ)
WU11_RS03370	COG0288	reversible hydration of carbon dioxide
WU11_RS03375	COG0154	amidase activity
WU11_RS03385	COG4211	Belongs to the binding-protein-dependent transport system permease family
WU11_RS03415	COG1464	Belongs to the NlpA lipoprotein family
WU11_RS03560	COG1196	nuclear chromosome segregation
WU11_RS03630	COG2135	peptidase activity
WU11_RS03645	COG0494	nUDIX hydrolase
WU11_RS03650	COG0442	prolyl-tRNA aminoacylation
WU11_RS03655	COG0824	Thioesterase
WU11_RS03660	COG0811	peptide transport
WU11_RS03665	COG0848	biopolymer transport protein
WU11_RS03675	COG0823	Involved in the tonB-independent uptake of proteins
WU11_RS03690	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WU11_RS03695	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
WU11_RS03730	COG0700	Nucleoside recognition
WU11_RS03735	COG0469	pyruvate kinase activity
WU11_RS03740	COG1929	Belongs to the glycerate kinase type-1 family
WU11_RS03745	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
WU11_RS03750	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
WU11_RS03755	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
WU11_RS03765	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
WU11_RS03775	COG2154	pterin-4-alpha-carbinolamine dehydratase
WU11_RS03800	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
WU11_RS03805	COG0154	amidase activity
WU11_RS03815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WU11_RS03820	COG0601	transmembrane transport
WU11_RS03825	COG0747	negative chemotaxis
WU11_RS03845	COG0019	diaminopimelate decarboxylase activity
WU11_RS03860	COG2353	YceI-like domain
WU11_RS03865	COG4774	siderophore transport
WU11_RS03870	COG3712	iron ion homeostasis
WU11_RS03910	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
WU11_RS03915	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
WU11_RS03920	COG0211	Belongs to the bacterial ribosomal protein bL27 family
WU11_RS03925	COG0261	This protein binds to 23S rRNA in the presence of protein L20
WU11_RS03935	COG0142	geranyltranstransferase activity
WU11_RS03945	COG0583	DNA-binding transcription factor activity
WU11_RS03955	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
WU11_RS03960	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WU11_RS03975	COG2994	toxin metabolic process
WU11_RS03985	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
WU11_RS03990	COG2274	protein secretion by the type I secretion system
WU11_RS03995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WU11_RS04000	COG1538	Outer membrane efflux protein
WU11_RS04015	COG0765	amino acid transport
WU11_RS04020	COG0765	amino acid transport
WU11_RS04025	COG1126	abc transporter atp-binding protein
WU11_RS04045	COG1028	Short-chain dehydrogenase reductase Sdr
WU11_RS04055	COG1802	Transcriptional regulator
WU11_RS04065	COG1802	Transcriptional regulator
WU11_RS04075	COG0318	PFAM AMP-dependent synthetase and ligase
WU11_RS04085	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WU11_RS04105	COG0028	Belongs to the TPP enzyme family
WU11_RS04125	COG0308	aminopeptidase N
WU11_RS04130	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
WU11_RS04140	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
WU11_RS04145	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
WU11_RS04150	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
WU11_RS04155	COG0560	Phosphoserine phosphatase
WU11_RS04160	COG0583	DNA-binding transcription factor activity
WU11_RS04165	COG3181	Tripartite tricarboxylate transporter family receptor
WU11_RS04170	COG0028	Belongs to the TPP enzyme family
WU11_RS04185	COG4774	siderophore transport
WU11_RS04190	COG4774	siderophore transport
WU11_RS04200	COG1007	ATP synthesis coupled electron transport
WU11_RS04215	COG0713	ATP synthesis coupled electron transport
WU11_RS04225	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WU11_RS04230	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
WU11_RS04235	COG1034	ATP synthesis coupled electron transport
WU11_RS04245	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
WU11_RS04250	COG0649	NAD binding
WU11_RS04255	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WU11_RS04260	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WU11_RS04265	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WU11_RS04270	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WU11_RS04300	COG0671	phosphoesterase, PA-phosphatase related
WU11_RS04310	COG1597	lipid kinase activity
WU11_RS04315	COG0583	DNA-binding transcription factor activity
WU11_RS04320	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
WU11_RS04330	COG1733	regulation of RNA biosynthetic process
WU11_RS04335	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WU11_RS04340	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WU11_RS04355	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
WU11_RS04375	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WU11_RS04395	COG3608	succinylglutamate desuccinylase aspartoacylase
WU11_RS04400	COG0626	cystathionine gamma-synthase activity
WU11_RS04405	COG0583	DNA-binding transcription factor activity
WU11_RS04440	COG3799	methylaspartate ammonia-lyase activity
WU11_RS04450	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
WU11_RS04460	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
WU11_RS04465	COG0149	triose-phosphate isomerase activity
WU11_RS04485	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
WU11_RS04500	COG1185	polyribonucleotide nucleotidyltransferase activity
WU11_RS04505	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
WU11_RS04520	COG1183	phosphatidylcholine synthase activity
WU11_RS04525	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
WU11_RS04530	COG0440	acetolactate synthase activity
WU11_RS04535	COG0028	Belongs to the TPP enzyme family
WU11_RS04555	COG5265	(ABC) transporter
WU11_RS04560	COG0500	methyltransferase
WU11_RS04580	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
WU11_RS04600	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
WU11_RS04610	COG0511	ligase activity, forming carbon-carbon bonds
WU11_RS04635	COG2188	Transcriptional regulator
WU11_RS04640	COG0439	Biotin carboxylase
WU11_RS04645	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
WU11_RS04690	COG5265	(ABC) transporter
WU11_RS04700	COG0667	Aldo Keto reductase
WU11_RS04715	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
WU11_RS04755	COG0583	DNA-binding transcription factor activity
WU11_RS04780	COG2814	Major facilitator Superfamily
WU11_RS04790	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
WU11_RS04805	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
WU11_RS04815	COG0287	Prephenate dehydrogenase
WU11_RS04820	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
WU11_RS04825	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
WU11_RS04845	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
WU11_RS04850	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
WU11_RS04855	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WU11_RS04860	COG1596	polysaccharide export
WU11_RS04860	COG1555	photosystem II stabilization
WU11_RS04875	COG2951	lytic endotransglycosylase activity
WU11_RS04880	COG0123	including yeast histone deacetylase and acetoin utilization protein
WU11_RS04895	COG1960	acyl-CoA dehydrogenase activity
WU11_RS04900	COG0450	alkyl hydroperoxide reductase
WU11_RS04915	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
WU11_RS04920	COG4208	sulfate ABC transporter
WU11_RS04925	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
WU11_RS04955	COG0335	large ribosomal subunit rRNA binding
WU11_RS04970	COG0667	Aldo Keto reductase
WU11_RS04980	COG2814	Major facilitator Superfamily
WU11_RS04985	COG3161	chorismate lyase activity
WU11_RS04990	COG1187	pseudouridine synthase activity
WU11_RS05000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WU11_RS05020	COG1999	signal sequence binding
WU11_RS05025	COG0339	signal peptide processing
WU11_RS05030	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
WU11_RS05035	COG4566	intracellular signal transduction
WU11_RS05045	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
WU11_RS05050	COG0508	dehydrogenase complex catalyzes the overall conversion of
WU11_RS05055	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WU11_RS05060	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
WU11_RS05070	COG1385	rRNA (uridine-N3-)-methyltransferase activity
WU11_RS05075	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
WU11_RS05080	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
WU11_RS05085	COG0126	phosphoglycerate kinase activity
WU11_RS05090	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
WU11_RS05095	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
WU11_RS05110	COG0625	glutathione transferase activity
WU11_RS05145	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
WU11_RS05155	COG0521	Mo-molybdopterin cofactor biosynthetic process
WU11_RS05165	COG0739	heme binding
WU11_RS05175	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
WU11_RS05210	COG0745	RESPONSE REGULATOR receiver
WU11_RS05225	COG0840	transmembrane signaling receptor activity
WU11_RS05235	COG2201	protein-glutamate methylesterase activity
WU11_RS05240	COG0745	RESPONSE REGULATOR receiver
WU11_RS05245	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
WU11_RS05270	COG0667	Aldo Keto reductase
WU11_RS05280	COG4535	Mg2 and Co2 transporter CorC
WU11_RS05285	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
WU11_RS05290	COG1702	phosphate starvation-inducible protein PhoH
WU11_RS05295	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
WU11_RS05310	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WU11_RS05315	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WU11_RS05320	COG1862	Preprotein translocase
WU11_RS05325	COG0343	queuine tRNA-ribosyltransferase activity
WU11_RS05330	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
WU11_RS05335	COG2027	D-alanyl-D-alanine carboxypeptidase
WU11_RS05340	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
WU11_RS05350	COG3468	outer membrane autotransporter barrel domain protein
WU11_RS05355	COG1648	precorrin-2 dehydrogenase activity
WU11_RS05355	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
WU11_RS05380	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
WU11_RS05385	COG0741	lytic transglycosylase activity
WU11_RS05390	COG0436	Aminotransferase
WU11_RS05400	COG0281	malic enzyme
WU11_RS05400	COG0280	phosphate acetyltransferase
WU11_RS05410	COG2732	(Barnase) inhibitor
WU11_RS05425	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
WU11_RS05450	COG0248	Ppx GppA phosphatase
WU11_RS05460	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
WU11_RS05470	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
WU11_RS05475	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
WU11_RS05480	COG1534	Rna-binding protein
WU11_RS05510	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
WU11_RS05525	COG1295	ribonuclease BN
WU11_RS05535	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
WU11_RS05540	COG0745	RESPONSE REGULATOR receiver
WU11_RS05545	COG2205	protein histidine kinase activity
WU11_RS05580	COG1022	Amp-dependent synthetase and ligase
WU11_RS05595	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
WU11_RS05600	COG1028	Short-chain dehydrogenase reductase Sdr
WU11_RS05610	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
WU11_RS05625	COG1136	(ABC) transporter
WU11_RS05630	COG0084	hydrolase, TatD family'
WU11_RS05660	COG0658	competence protein
WU11_RS05660	COG2333	competence protein COMEC
WU11_RS05670	COG0613	PHP domain protein
WU11_RS05685	COG3539	Fimbrial protein
WU11_RS05690	COG0280	phosphate acetyltransferase
WU11_RS05690	COG0281	malic enzyme
WU11_RS05700	COG1522	sequence-specific DNA binding
WU11_RS05710	COG0567	Dehydrogenase, E1 component
WU11_RS05715	COG0508	dehydrogenase complex catalyzes the overall conversion of
WU11_RS05720	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WU11_RS05725	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
WU11_RS05730	COG1028	Short-chain dehydrogenase reductase Sdr
WU11_RS05735	COG0583	DNA-binding transcription factor activity
WU11_RS05745	COG3181	Tripartite tricarboxylate transporter family receptor
WU11_RS05770	COG0180	Tryptophanyl-tRNA synthetase
WU11_RS05775	COG2183	response to ionizing radiation
WU11_RS05780	COG1199	ATP-dependent helicase activity
WU11_RS05790	COG0564	pseudouridine synthase activity
WU11_RS05800	COG3243	poly(R)-hydroxyalkanoic acid synthase
WU11_RS05805	COG1028	Short-chain dehydrogenase reductase Sdr
WU11_RS05810	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
WU11_RS05825	COG0672	)-iron permease
WU11_RS05865	COG0583	DNA-binding transcription factor activity
WU11_RS05875	COG2814	Major facilitator Superfamily
WU11_RS05890	COG1619	proteins homologs of microcin C7 resistance protein MccF
WU11_RS05905	COG2084	Dehydrogenase
WU11_RS05910	COG3181	Tripartite tricarboxylate transporter family receptor
WU11_RS05935	COG2988	succinylglutamate desuccinylase activity
WU11_RS05965	COG0765	amino acid transport
WU11_RS05970	COG0765	amino acid transport
WU11_RS05975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WU11_RS06010	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WU11_RS06015	COG1595	DNA-templated transcription, initiation
WU11_RS06025	COG3530	Putative quorum-sensing-regulated virulence factor
WU11_RS06030	COG0494	nUDIX hydrolase
WU11_RS06045	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
WU11_RS06050	COG0542	response to heat
WU11_RS06065	COG3468	outer membrane autotransporter barrel domain protein
WU11_RS06070	COG3468	outer membrane autotransporter barrel domain protein
WU11_RS06080	COG5441	Belongs to the UPF0261 family
WU11_RS06085	COG5564	TIM-barrel signal transduction protein
WU11_RS06100	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
WU11_RS06115	COG1477	protein flavinylation
WU11_RS06135	COG1131	(ABC) transporter
WU11_RS06140	COG0842	Transport permease protein
WU11_RS06150	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
WU11_RS06155	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
WU11_RS06155	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
WU11_RS06160	COG1562	ergosterol biosynthetic process
WU11_RS06165	COG1562	ergosterol biosynthetic process
WU11_RS06170	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
WU11_RS06175	COG1028	Short-chain dehydrogenase reductase Sdr
WU11_RS06195	COG2304	oxidoreductase activity
WU11_RS06215	COG0534	Mate efflux family protein
WU11_RS06225	COG0254	rRNA binding
WU11_RS06230	COG3483	tryptophan 2,3-dioxygenase activity
WU11_RS06235	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
WU11_RS06240	COG2003	Belongs to the UPF0758 family
WU11_RS06245	COG1047	Peptidyl-prolyl cis-trans
WU11_RS06250	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
WU11_RS06255	COG0625	glutathione transferase activity
WU11_RS06275	COG0523	cobalamin synthesis protein
WU11_RS06285	COG0583	DNA-binding transcription factor activity
WU11_RS06295	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
WU11_RS06300	COG1187	pseudouridine synthase activity
WU11_RS06305	COG0779	Required for maturation of 30S ribosomal subunits
WU11_RS06310	COG2251	uridine kinase activity
WU11_RS06310	COG0195	Participates in both transcription termination and antitermination
WU11_RS06315	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
WU11_RS06320	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
WU11_RS06325	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
WU11_RS06345	COG1611	Belongs to the LOG family
WU11_RS06360	COG0412	Dienelactone hydrolase
WU11_RS06365	COG1283	sodium-dependent phosphate transmembrane transporter activity
WU11_RS06370	COG1760	l-serine dehydratase
WU11_RS06375	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
WU11_RS06380	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
WU11_RS06390	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
WU11_RS06415	COG2311	Membrane
WU11_RS06425	COG0697	spore germination
WU11_RS06440	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
WU11_RS06455	COG0559	Belongs to the binding-protein-dependent transport system permease family
WU11_RS06470	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
WU11_RS06480	COG1653	transport
WU11_RS06485	COG1175	transmembrane transport
WU11_RS06490	COG0395	ABC-type sugar transport system, permease component
WU11_RS06495	COG3842	ATPase activity
WU11_RS06520	COG2363	Small membrane protein
WU11_RS06535	COG1464	Belongs to the NlpA lipoprotein family
WU11_RS06545	COG0688	phosphatidylethanolamine metabolic process
WU11_RS06570	COG0625	glutathione transferase activity
WU11_RS06575	COG0386	Belongs to the glutathione peroxidase family
WU11_RS06595	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU11_RS06630	COG2259	Doxx family
WU11_RS06645	COG0667	Aldo Keto reductase
WU11_RS06675	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
WU11_RS06695	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
WU11_RS06705	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
WU11_RS06745	COG0392	lysyltransferase activity
WU11_RS06760	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WU11_RS06765	COG3568	Endonuclease Exonuclease Phosphatase
WU11_RS06775	COG1695	Transcriptional regulator
WU11_RS06795	COG0583	DNA-binding transcription factor activity
WU11_RS06810	COG1802	Transcriptional regulator
WU11_RS06820	COG3181	Tripartite tricarboxylate transporter family receptor
WU11_RS06830	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU11_RS06845	COG0066	3-isopropylmalate dehydratase activity
WU11_RS06855	COG3181	Tripartite tricarboxylate transporter family receptor
WU11_RS06860	COG4948	Mandelate Racemase Muconate Lactonizing
WU11_RS06875	COG1126	abc transporter atp-binding protein
WU11_RS06880	COG0765	amino acid transport
WU11_RS06885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WU11_RS06905	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
WU11_RS06930	COG1815	bacterial-type flagellum-dependent cell motility
WU11_RS06935	COG1558	bacterial-type flagellum-dependent cell motility
WU11_RS06945	COG1749	Flagellar hook protein flgE
WU11_RS06960	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
WU11_RS06965	COG1706	bacterial-type flagellum-dependent cell motility
WU11_RS06975	COG1256	bacterial-type flagellum assembly
WU11_RS06985	COG0840	transmembrane signaling receptor activity
WU11_RS06990	COG0840	transmembrane signaling receptor activity
WU11_RS06995	COG0840	transmembrane signaling receptor activity
WU11_RS07015	COG1338	Plays a role in the flagellum-specific transport system
WU11_RS07035	COG1580	Controls the rotational direction of flagella during chemotaxis
WU11_RS07060	COG1157	protein secretion by the type III secretion system
WU11_RS07070	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
WU11_RS07080	COG1677	Flagellar hook-basal body complex protein FliE
WU11_RS07090	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
WU11_RS07125	COG0285	dihydrofolate synthase activity
WU11_RS07155	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
WU11_RS07160	COG0024	Methionine aminopeptidase
WU11_RS07165	COG0052	Belongs to the universal ribosomal protein uS2 family
WU11_RS07170	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
WU11_RS07175	COG0528	UMP kinase activity
WU11_RS07180	COG0233	cytoplasmic translational termination
WU11_RS07185	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
WU11_RS07195	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
WU11_RS07200	COG0750	zinc metalloprotease
WU11_RS07205	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
WU11_RS07210	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
WU11_RS07215	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
WU11_RS07220	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
WU11_RS07230	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
WU11_RS07235	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
WU11_RS07240	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
WU11_RS07245	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
WU11_RS07255	COG0518	GMP synthase (glutamine-hydrolyzing) activity
WU11_RS07255	COG0519	Catalyzes the synthesis of GMP from XMP
WU11_RS07270	COG0330	HflC and HflK could
WU11_RS07275	COG3706	GGDEF domain
WU11_RS07280	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
WU11_RS07290	COG2867	negative regulation of translational initiation
WU11_RS07300	COG1960	acyl-CoA dehydrogenase activity
WU11_RS07305	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
WU11_RS07335	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
WU11_RS07340	COG0505	Belongs to the CarA family
WU11_RS07345	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
WU11_RS07355	COG0406	alpha-ribazole phosphatase activity
WU11_RS07365	COG3842	ATPase activity
WU11_RS07385	COG5001	Diguanylate cyclase
WU11_RS07390	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
WU11_RS07400	COG1763	Mo-molybdopterin cofactor biosynthetic process
WU11_RS07405	COG0303	'Molybdopterin
WU11_RS07410	COG0746	molybdenum cofactor guanylyltransferase activity
WU11_RS07415	COG0489	protein tyrosine kinase activity
WU11_RS07445	COG0243	molybdopterin cofactor binding
WU11_RS07445	COG3383	formate dehydrogenase (NAD+) activity
WU11_RS07450	COG0437	4 iron, 4 sulfur cluster binding
WU11_RS07480	COG1122	ATPase activity
WU11_RS07490	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
WU11_RS07495	COG0066	3-isopropylmalate dehydratase activity
WU11_RS07500	COG0473	3-isopropylmalate dehydrogenase activity
WU11_RS07505	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
WU11_RS07515	COG0101	tRNA pseudouridine synthase activity
WU11_RS07520	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
WU11_RS07535	COG0135	phosphoribosylanthranilate isomerase activity
WU11_RS07550	COG3022	response to hydroperoxide
WU11_RS07560	COG1289	transmembrane transporter activity
WU11_RS07580	COG0635	Involved in the biosynthesis of porphyrin-containing compound
WU11_RS07590	COG2197	response regulator
WU11_RS07595	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
WU11_RS07600	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
WU11_RS07605	COG0189	ligase activity
WU11_RS07615	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
WU11_RS07620	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
WU11_RS07630	COG1764	response to oxidative stress
WU11_RS07635	COG2423	ornithine cyclodeaminase activity
WU11_RS07645	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WU11_RS07650	COG0765	amino acid transport
WU11_RS07655	COG0765	amino acid transport
WU11_RS07660	COG1126	abc transporter atp-binding protein
WU11_RS07715	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
WU11_RS07725	COG2944	sequence-specific DNA binding
WU11_RS07735	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
WU11_RS07740	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
WU11_RS07745	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
WU11_RS07750	COG0009	L-threonylcarbamoyladenylate synthase
WU11_RS07755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WU11_RS07760	COG1414	Transcriptional regulator
WU11_RS07775	COG0765	amino acid transport
WU11_RS07780	COG1126	abc transporter atp-binding protein
WU11_RS07785	COG0028	Belongs to the TPP enzyme family
WU11_RS07800	COG0028	Belongs to the TPP enzyme family
WU11_RS07805	COG0583	DNA-binding transcription factor activity
WU11_RS07810	COG4974	Belongs to the 'phage' integrase family
WU11_RS07815	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
WU11_RS07820	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
WU11_RS07835	COG1686	Belongs to the peptidase S11 family
WU11_RS07845	COG2814	Major facilitator Superfamily
WU11_RS07855	COG1074	ATP-dependent DNA helicase activity
WU11_RS07870	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
WU11_RS07875	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
WU11_RS07880	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
WU11_RS07900	COG2321	neutral zinc metallopeptidase
WU11_RS07905	COG0009	L-threonylcarbamoyladenylate synthase
WU11_RS07950	COG3360	Dodecin
WU11_RS07955	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
WU11_RS07960	COG2850	peptidyl-arginine hydroxylation
WU11_RS07965	COG3539	Fimbrial protein
WU11_RS07970	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
WU11_RS07975	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WU11_RS07995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WU11_RS08000	COG0765	amino acid transport
WU11_RS08005	COG1126	abc transporter atp-binding protein
WU11_RS08010	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
WU11_RS08015	COG1758	RNA polymerase activity
WU11_RS08020	COG0194	GDP metabolic process
WU11_RS08025	COG3258	Cytochrome c
WU11_RS08030	COG2863	cytochrome
WU11_RS08035	COG1028	Short-chain dehydrogenase reductase Sdr
WU11_RS08040	COG0791	NLP P60 protein
WU11_RS08045	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
WU11_RS08065	COG1561	YicC-like family, N-terminal region
WU11_RS08070	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
WU11_RS08085	COG0840	transmembrane signaling receptor activity
WU11_RS08090	COG2199	diguanylate cyclase activity
WU11_RS08090	COG2200	EAL domain
WU11_RS08095	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
WU11_RS08105	COG0635	Involved in the biosynthesis of porphyrin-containing compound
WU11_RS08110	COG0174	glutamine synthetase
WU11_RS08120	COG2204	response regulator
WU11_RS08125	COG0583	DNA-binding transcription factor activity
WU11_RS08130	COG1741	Belongs to the pirin family
WU11_RS08135	COG1741	Belongs to the pirin family
WU11_RS08145	COG3842	ATPase activity
WU11_RS08150	COG1178	ABC-type Fe3 transport system permease component
WU11_RS08155	COG1840	ABC-type Fe3 transport system, periplasmic component
WU11_RS08165	COG0583	DNA-binding transcription factor activity
WU11_RS08175	COG0656	L-ascorbic acid biosynthetic process
WU11_RS08190	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
WU11_RS08195	COG0583	DNA-binding transcription factor activity
WU11_RS08210	COG0783	Belongs to the Dps family
WU11_RS08230	COG0463	Glycosyl transferase, family 2
WU11_RS08250	COG0438	transferase activity, transferring glycosyl groups
WU11_RS08265	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
WU11_RS08290	COG0300	oxidoreductase activity
WU11_RS08335	COG0861	Integral membrane protein TerC family
WU11_RS08340	COG1028	Short-chain dehydrogenase reductase Sdr
WU11_RS08360	COG0714	Associated with various cellular activities
WU11_RS08390	COG3119	arylsulfatase activity
WU11_RS08415	COG2197	response regulator
WU11_RS08425	COG2944	sequence-specific DNA binding
WU11_RS08430	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
WU11_RS08435	COG0625	glutathione transferase activity
WU11_RS08465	COG0179	Fumarylacetoacetate (FAA) hydrolase
WU11_RS08470	COG1028	Short-chain dehydrogenase reductase Sdr
WU11_RS08520	COG0431	NADPH-dependent FMN reductase
WU11_RS08550	COG1028	Short-chain dehydrogenase reductase Sdr
WU11_RS08555	COG0583	DNA-binding transcription factor activity
WU11_RS08570	COG3181	Tripartite tricarboxylate transporter family receptor
WU11_RS08575	COG2111	Na H antiporter
WU11_RS08575	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
WU11_RS08580	COG1006	Multisubunit Na H antiporter MnhC subunit
WU11_RS08585	COG0651	ATP synthesis coupled electron transport
WU11_RS08590	COG1863	multisubunit Na H antiporter MnhE subunit
WU11_RS08595	COG2212	antiporter activity
WU11_RS08620	COG0590	tRNA wobble adenosine to inosine editing
WU11_RS08625	COG1619	proteins homologs of microcin C7 resistance protein MccF
WU11_RS08630	COG1024	Enoyl-CoA hydratase
WU11_RS08645	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
WU11_RS08650	COG0488	(ABC) transporter
WU11_RS08685	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WU11_RS08685	COG1017	nitric oxide dioxygenase activity
WU11_RS08690	COG1959	2 iron, 2 sulfur cluster binding
WU11_RS08695	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WU11_RS08715	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
WU11_RS08720	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
WU11_RS08725	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
WU11_RS08730	COG0084	hydrolase, TatD family'
WU11_RS08745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WU11_RS08755	COG1126	abc transporter atp-binding protein
WU11_RS08760	COG0010	Belongs to the arginase family
WU11_RS08765	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
WU11_RS08770	COG1012	belongs to the aldehyde dehydrogenase family
WU11_RS08780	COG0028	Belongs to the TPP enzyme family
WU11_RS08790	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
WU11_RS08790	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
WU11_RS08800	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
WU11_RS08815	COG3189	MarR family transcriptional regulator
WU11_RS08820	COG2010	Cytochrome c
WU11_RS08845	COG4336	lyase activity
WU11_RS08855	COG2205	protein histidine kinase activity
WU11_RS08855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WU11_RS08860	COG2197	response regulator
WU11_RS08865	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
WU11_RS08865	COG3064	Membrane
WU11_RS08865	COG3210	domain, Protein
WU11_RS08875	COG3121	Chaperone
WU11_RS08880	COG3188	usher protein
WU11_RS08885	COG3539	Fimbrial protein
WU11_RS08890	COG2831	hemolysin activation secretion protein
WU11_RS08905	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
WU11_RS08930	COG0583	DNA-binding transcription factor activity
WU11_RS08955	COG0668	transmembrane transport
WU11_RS08975	COG0483	inositol monophosphate 1-phosphatase activity
WU11_RS08980	COG1253	flavin adenine dinucleotide binding
WU11_RS08985	COG1968	undecaprenyl-diphosphatase activity
WU11_RS08990	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
WU11_RS09005	COG0215	cysteine-tRNA ligase activity
WU11_RS09015	COG0825	malonyl-CoA metabolic process
WU11_RS09025	COG0037	tRNA processing
WU11_RS09030	COG0527	aspartate kinase activity
WU11_RS09055	COG1250	3-hydroxyacyl-CoA dehydrogenase
WU11_RS09060	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
WU11_RS09060	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
WU11_RS09075	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
WU11_RS09080	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
WU11_RS09085	COG1028	Short-chain dehydrogenase reductase Sdr
WU11_RS09095	COG0583	DNA-binding transcription factor activity
WU11_RS09125	COG3842	ATPase activity
WU11_RS09135	COG0446	pyridine nucleotide-disulphide oxidoreductase
WU11_RS09135	COG1902	pentaerythritol trinitrate reductase activity
WU11_RS09140	COG1414	Transcriptional regulator
WU11_RS09145	COG1832	CoA-binding protein
WU11_RS09155	COG0251	oxidation-reduction process
WU11_RS09180	COG1902	pentaerythritol trinitrate reductase activity
WU11_RS09190	COG1215	transferase activity, transferring glycosyl groups
WU11_RS09195	COG1649	PFAM Uncharacterised BCR, COG1649
WU11_RS09195	COG0726	polysaccharide deacetylase
WU11_RS09215	COG1846	Transcriptional regulator
WU11_RS09220	COG2197	response regulator
WU11_RS09235	COG0166	Belongs to the GPI family
WU11_RS09240	COG1045	serine acetyltransferase
WU11_RS09250	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
WU11_RS09255	COG0483	inositol monophosphate 1-phosphatase activity
WU11_RS09260	COG1012	belongs to the aldehyde dehydrogenase family
WU11_RS09265	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
WU11_RS09280	COG0210	DNA helicase
WU11_RS09285	COG0598	Magnesium transport protein CorA
WU11_RS09295	COG0747	negative chemotaxis
WU11_RS09300	COG0601	transmembrane transport
WU11_RS09305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WU11_RS09310	COG4172	Belongs to the ABC transporter superfamily
WU11_RS09315	COG1846	Transcriptional regulator
WU11_RS09365	COG4964	Belongs to the GSP D family
WU11_RS09405	COG2204	response regulator
WU11_RS09420	COG1595	DNA-templated transcription, initiation
WU11_RS09430	COG3474	cytochrome
WU11_RS09435	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
WU11_RS09450	COG3384	dioxygenase
WU11_RS09455	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
WU11_RS09480	COG2885	chlorophyll binding
WU11_RS09515	COG0697	spore germination
WU11_RS09520	COG0730	response to heat
WU11_RS09540	COG0583	DNA-binding transcription factor activity
WU11_RS09545	COG0427	acetyl-CoA hydrolase
WU11_RS09600	COG1250	3-hydroxyacyl-CoA dehydrogenase
WU11_RS09605	COG0154	amidase activity
WU11_RS09615	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
WU11_RS09630	COG0495	leucyl-tRNA aminoacylation
WU11_RS09635	COG2814	Major facilitator Superfamily
WU11_RS09665	COG0267	Belongs to the bacterial ribosomal protein bL33 family
WU11_RS09670	COG0227	Belongs to the bacterial ribosomal protein bL28 family
WU11_RS09675	COG2814	Major facilitator Superfamily
WU11_RS09680	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
WU11_RS09695	COG4176	ABC-type proline glycine betaine transport system permease component
WU11_RS09705	COG1942	4-Oxalocrotonate Tautomerase
WU11_RS09710	COG0183	Belongs to the thiolase family
WU11_RS09720	COG1802	Transcriptional regulator
WU11_RS09730	COG1024	Enoyl-CoA hydratase
WU11_RS09735	COG0318	PFAM AMP-dependent synthetase and ligase
WU11_RS09740	COG0318	PFAM AMP-dependent synthetase and ligase
WU11_RS09750	COG2032	superoxide dismutase activity
WU11_RS09765	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
WU11_RS09790	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WU11_RS09795	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WU11_RS09805	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
WU11_RS09810	COG0736	holo-[acyl-carrier-protein] synthase activity
WU11_RS09815	COG1472	Belongs to the glycosyl hydrolase 3 family
WU11_RS09820	COG0322	excinuclease ABC activity
WU11_RS09825	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
WU11_RS09840	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
WU11_RS09840	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
WU11_RS09845	COG2224	Isocitrate lyase
WU11_RS09865	COG0559	Belongs to the binding-protein-dependent transport system permease family
WU11_RS09875	COG4638	Rieske (2fe-2S)
WU11_RS09885	COG1024	Enoyl-CoA hydratase
WU11_RS09895	COG0633	Ferredoxin
WU11_RS09900	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU11_RS09915	COG0183	Belongs to the thiolase family
WU11_RS09960	COG2346	COG2346, Truncated hemoglobins
WU11_RS10090	COG2207	Transcriptional regulator
WU11_RS10135	COG1132	(ABC) transporter
WU11_RS10160	COG0659	secondary active sulfate transmembrane transporter activity
WU11_RS10190	COG2169	Transcriptional regulator
WU11_RS10195	COG5507	3-demethylubiquinone-9 3-methyltransferase
WU11_RS10200	COG0384	phenazine biosynthesis protein PhzF
WU11_RS10205	COG0583	DNA-binding transcription factor activity
WU11_RS10210	COG2733	membrane
WU11_RS10225	COG1012	belongs to the aldehyde dehydrogenase family
WU11_RS10230	COG3284	Transcriptional regulator
WU11_RS10250	COG1380	Effector of murein hydrolase LrgA
WU11_RS10255	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
WU11_RS10255	COG4106	trans-aconitate 2-methyltransferase activity
WU11_RS10265	COG0156	8-amino-7-oxononanoate synthase activity
WU11_RS10335	COG1131	(ABC) transporter
WU11_RS10340	COG0842	Transport permease protein
WU11_RS10345	COG0628	permease
WU11_RS10380	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
WU11_RS10390	COG0828	Belongs to the bacterial ribosomal protein bS21 family
WU11_RS10395	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
WU11_RS10400	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
WU11_RS10405	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
WU11_RS10410	COG0330	HflC and HflK could
WU11_RS10415	COG0330	HflC and HflK could
WU11_RS10420	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
WU11_RS10425	COG1923	regulation of RNA biosynthetic process
WU11_RS10430	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
WU11_RS10435	COG1160	GTP binding
WU11_RS10440	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
WU11_RS10445	COG2976	Protein conserved in bacteria
WU11_RS10450	COG0124	histidyl-tRNA synthetase
WU11_RS10455	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
WU11_RS10465	COG0820	rRNA (adenine-C2-)-methyltransferase activity
WU11_RS10470	COG0105	UTP biosynthetic process
WU11_RS10475	COG0525	valine-tRNA ligase activity
WU11_RS10490	COG0642	Histidine kinase
WU11_RS10510	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
WU11_RS10515	COG0336	Belongs to the RNA methyltransferase TrmD family
WU11_RS10520	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
WU11_RS10525	COG0228	four-way junction DNA binding
WU11_RS10535	COG0425	Belongs to the sulfur carrier protein TusA family
WU11_RS10540	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
WU11_RS10585	COG0154	amidase activity
WU11_RS10590	COG4172	Belongs to the ABC transporter superfamily
WU11_RS10595	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WU11_RS10600	COG0601	transmembrane transport
WU11_RS10605	COG0747	negative chemotaxis
WU11_RS10635	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WU11_RS10645	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
WU11_RS10660	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
WU11_RS10665	COG3395	kinase activity
WU11_RS10680	COG1024	Enoyl-CoA hydratase
WU11_RS10700	COG0633	Ferredoxin
WU11_RS10705	COG0443	Heat shock 70 kDa protein
WU11_RS10710	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
WU11_RS10715	COG0316	Belongs to the HesB IscA family
WU11_RS10720	COG0822	iron-sulfur transferase activity
WU11_RS10725	COG1104	cysteine desulfurase activity
WU11_RS10735	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
WU11_RS10740	COG0556	nucleotide-excision repair
WU11_RS10750	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
WU11_RS10755	COG3468	outer membrane autotransporter barrel domain protein
WU11_RS10785	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
WU11_RS10800	COG1960	acyl-CoA dehydrogenase activity
WU11_RS10805	COG1028	Short-chain dehydrogenase reductase Sdr
WU11_RS10810	COG0183	Belongs to the thiolase family
WU11_RS10820	COG1024	Enoyl-CoA hydratase
WU11_RS10835	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU11_RS10840	COG0583	DNA-binding transcription factor activity
WU11_RS10845	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
WU11_RS10850	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
WU11_RS10855	COG0740	serine-type endopeptidase activity
WU11_RS10860	COG0544	peptidyl-prolyl cis-trans isomerase activity
WU11_RS10880	COG1278	Cold shock
WU11_RS10915	COG2171	N-acyltransferase activity
WU11_RS10920	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
WU11_RS10925	COG2890	protein-(glutamine-N5) methyltransferase activity
WU11_RS10930	COG0488	(ABC) transporter
WU11_RS10935	COG4771	TonB-dependent receptor
WU11_RS10940	COG0210	DNA helicase
WU11_RS10960	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
WU11_RS10965	COG0196	riboflavin kinase activity
WU11_RS10970	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
WU11_RS10975	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
WU11_RS10980	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
WU11_RS10990	COG1522	sequence-specific DNA binding
WU11_RS11010	COG2951	lytic endotransglycosylase activity
WU11_RS11015	COG2833	Protein of unknown function (DUF455)
WU11_RS11035	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
WU11_RS11035	COG0189	ligase activity
WU11_RS11040	COG1181	Belongs to the D-alanine--D-alanine ligase family
WU11_RS11040	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
WU11_RS11045	COG3237	CsbD-like
WU11_RS11055	COG2823	Periplasmic or secreted lipoprotein
WU11_RS11065	COG4181	ATPase activity
WU11_RS11075	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
WU11_RS11080	COG0584	glycerophosphoryl diester phosphodiesterase
WU11_RS11085	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
WU11_RS11095	COG0678	peroxiredoxin activity
WU11_RS11095	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
WU11_RS11105	COG0789	Transcriptional regulator
WU11_RS11110	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
WU11_RS11140	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
WU11_RS11145	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
WU11_RS11155	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
WU11_RS11160	COG2252	PERMEase
WU11_RS11170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
WU11_RS11200	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
WU11_RS11205	COG2358	TRAP transporter, solute receptor (TAXI family
WU11_RS11235	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WU11_RS11240	COG1366	Belongs to the anti-sigma-factor antagonist family
WU11_RS11245	COG2172	sigma factor antagonist activity
WU11_RS11250	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
WU11_RS11260	COG2770	Histidine kinase
WU11_RS11260	COG2208	phosphoserine phosphatase activity
WU11_RS11280	COG1595	DNA-templated transcription, initiation
WU11_RS11295	COG4792	protein secretion
WU11_RS11300	COG4791	protein targeting
WU11_RS11305	COG4794	Type iii secretion
WU11_RS11310	COG4790	Type iii secretion
WU11_RS11345	COG4669	(LipO)protein
WU11_RS11410	COG4789	Type iii secretion
WU11_RS11440	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
WU11_RS11445	COG0840	transmembrane signaling receptor activity
WU11_RS11450	COG2233	PERMEase
WU11_RS11470	COG0492	ferredoxin-NADP+ reductase activity
WU11_RS11475	COG1840	ABC-type Fe3 transport system, periplasmic component
WU11_RS11480	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
WU11_RS11485	COG1178	ABC-type Fe3 transport system permease component
WU11_RS11490	COG3842	ATPase activity
WU11_RS11495	COG0583	DNA-binding transcription factor activity
WU11_RS11515	COG0501	Belongs to the peptidase M48B family
WU11_RS11525	COG0697	spore germination
WU11_RS11535	COG1846	Transcriptional regulator
WU11_RS11545	COG1566	PFAM secretion protein HlyD family protein
WU11_RS11550	COG2814	Major facilitator Superfamily
WU11_RS11555	COG0473	3-isopropylmalate dehydrogenase activity
WU11_RS11565	COG0747	negative chemotaxis
WU11_RS11575	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WU11_RS11590	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
WU11_RS11615	COG1012	belongs to the aldehyde dehydrogenase family
WU11_RS11625	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
WU11_RS11630	COG1115	amino acid carrier protein
WU11_RS11635	COG0433	COG0433 Predicted ATPase
WU11_RS11640	COG0217	transcriptional regulatory protein
WU11_RS11645	COG0151	Belongs to the GarS family
WU11_RS11650	COG0408	coproporphyrinogen oxidase activity
WU11_RS11655	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
WU11_RS11660	COG0799	negative regulation of ribosome biogenesis
WU11_RS11665	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
WU11_RS11670	COG0424	maF-like protein
WU11_RS11675	COG3468	outer membrane autotransporter barrel domain protein
WU11_RS11715	COG1530	ribonuclease E activity
WU11_RS11720	COG0077	Prephenate dehydratase
WU11_RS11735	COG1132	(ABC) transporter
WU11_RS11740	COG0859	PFAM glycosyl transferase family 9
WU11_RS11765	COG2194	sulfuric ester hydrolase activity
WU11_RS11770	COG0438	transferase activity, transferring glycosyl groups
WU11_RS11775	COG0463	Glycosyl transferase, family 2
WU11_RS11780	COG0726	polysaccharide deacetylase
WU11_RS11785	COG0438	transferase activity, transferring glycosyl groups
WU11_RS11800	COG1643	Atp-dependent helicase
WU11_RS11805	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
WU11_RS11805	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
WU11_RS11810	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
WU11_RS11820	COG0704	Plays a role in the regulation of phosphate uptake
WU11_RS11825	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
WU11_RS11830	COG1960	acyl-CoA dehydrogenase activity
WU11_RS11855	COG1177	transmembrane transport
WU11_RS11860	COG1176	ABC-type spermidine putrescine transport system, permease component I
WU11_RS11865	COG3842	ATPase activity
WU11_RS11870	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
WU11_RS11885	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
WU11_RS11890	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
WU11_RS11900	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
WU11_RS11900	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
WU11_RS11920	COG0372	Belongs to the citrate synthase family
WU11_RS11925	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
WU11_RS11930	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
WU11_RS11935	COG1053	succinate dehydrogenase
WU11_RS11940	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
WU11_RS11945	COG2009	succinate dehydrogenase
WU11_RS11950	COG2188	Transcriptional regulator
WU11_RS11955	COG0039	L-malate dehydrogenase activity
WU11_RS11985	COG1981	membrane
WU11_RS12010	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
WU11_RS12020	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
WU11_RS12050	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
WU11_RS12055	COG0148	phosphopyruvate hydratase activity
WU11_RS12065	COG2877	3-deoxy-8-phosphooctulonate synthase activity
WU11_RS12070	COG0504	CTP synthase activity
WU11_RS12095	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WU11_RS12105	COG0747	negative chemotaxis
WU11_RS12110	COG4172	Belongs to the ABC transporter superfamily
WU11_RS12115	COG1446	asparaginase
WU11_RS12145	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
WU11_RS12160	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
WU11_RS12165	COG0697	spore germination
WU11_RS12170	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
WU11_RS12180	COG3193	protein, possibly involved in utilization of glycolate and propanediol
WU11_RS12185	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
WU11_RS12190	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
WU11_RS12195	COG0791	NLP P60 protein
WU11_RS12210	COG0583	DNA-binding transcription factor activity
WU11_RS12225	COG0583	DNA-binding transcription factor activity
WU11_RS12235	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
WU11_RS12250	COG0670	Belongs to the BI1 family
WU11_RS12255	COG3181	Tripartite tricarboxylate transporter family receptor
WU11_RS12265	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
WU11_RS12275	COG1381	Involved in DNA repair and RecF pathway recombination
WU11_RS12280	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
WU11_RS12285	COG0571	ribonuclease III activity
WU11_RS12290	COG0681	Belongs to the peptidase S26 family
WU11_RS12295	COG0481	GTPase activity
WU11_RS12300	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WU11_RS12325	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
WU11_RS12330	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
WU11_RS12345	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
WU11_RS12350	COG0416	fatty acid biosynthetic process
WU11_RS12355	COG0333	Belongs to the bacterial ribosomal protein bL32 family
WU11_RS12360	COG1399	metal-binding, possibly nucleic acid-binding protein
WU11_RS12365	COG0424	maF-like protein
WU11_RS12375	COG3023	N-Acetylmuramoyl-L-alanine amidase
WU11_RS12380	COG1289	transmembrane transporter activity
WU11_RS12390	COG3022	response to hydroperoxide
WU11_RS12400	COG1028	Short-chain dehydrogenase reductase Sdr
WU11_RS12415	COG3486	L-lysine 6-monooxygenase (NADPH) activity
WU11_RS12445	COG2814	Major facilitator Superfamily
WU11_RS12465	COG3706	GGDEF domain
WU11_RS12490	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
WU11_RS12495	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
WU11_RS12500	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
WU11_RS12505	COG1674	ftsk spoiiie
WU11_RS12510	COG0492	ferredoxin-NADP+ reductase activity
WU11_RS12515	COG1193	negative regulation of DNA recombination
WU11_RS12535	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
WU11_RS12550	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
WU11_RS12555	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
WU11_RS12560	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
WU11_RS12570	COG0745	RESPONSE REGULATOR receiver
WU11_RS12615	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
WU11_RS12635	COG0612	Peptidase, M16
WU11_RS12645	COG0443	Heat shock 70 kDa protein
WU11_RS12655	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
WU11_RS12665	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
WU11_RS12670	COG1420	regulation of RNA biosynthetic process
WU11_RS12675	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
WU11_RS12680	COG0497	DNA recombination
WU11_RS12685	COG0735	belongs to the Fur family
WU11_RS12690	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
WU11_RS12695	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
WU11_RS12700	COG0812	UDP-N-acetylmuramate dehydrogenase activity
WU11_RS12735	COG0446	pyridine nucleotide-disulphide oxidoreductase
WU11_RS12735	COG0404	The glycine cleavage system catalyzes the degradation of glycine
WU11_RS12740	COG4311	Sarcosine oxidase, delta subunit
WU11_RS12745	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WU11_RS12755	COG0583	DNA-binding transcription factor activity
WU11_RS12765	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
WU11_RS12795	COG4964	Belongs to the GSP D family
WU11_RS12855	COG0181	hydroxymethylbilane synthase activity
WU11_RS12860	COG0861	Integral membrane protein TerC family
WU11_RS12865	COG0861	Integral membrane protein TerC family
WU11_RS12870	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
WU11_RS12875	COG0045	succinate-CoA ligase (ADP-forming) activity
WU11_RS12885	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
WU11_RS12895	COG2137	regulation of response to DNA damage stimulus
WU11_RS12900	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
WU11_RS12920	COG1250	3-hydroxyacyl-CoA dehydrogenase
WU11_RS12920	COG1024	Enoyl-CoA hydratase
WU11_RS12925	COG3842	ATPase activity
WU11_RS12940	COG1028	Short-chain dehydrogenase reductase Sdr
WU11_RS12960	COG0583	DNA-binding transcription factor activity
WU11_RS12965	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU11_RS12975	COG2974	May be involved in recombination
WU11_RS12980	COG0540	Belongs to the ATCase OTCase family
WU11_RS13055	COG0776	regulation of translation
WU11_RS13060	COG0072	phenylalanine-tRNA ligase activity
WU11_RS13060	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WU11_RS13065	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
WU11_RS13070	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
WU11_RS13075	COG0291	Belongs to the bacterial ribosomal protein bL35 family
WU11_RS13090	COG0756	dUTP diphosphatase activity
WU11_RS13100	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WU11_RS13115	COG0500	methyltransferase
WU11_RS13130	COG0586	Pfam SNARE associated Golgi protein
WU11_RS13160	COG1609	Transcriptional regulator
WU11_RS13165	COG4172	Belongs to the ABC transporter superfamily
WU11_RS13170	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WU11_RS13175	COG0601	transmembrane transport
WU11_RS13180	COG0747	negative chemotaxis
WU11_RS13195	COG1280	lysine exporter protein (LysE YggA)
WU11_RS13210	COG2814	Major facilitator Superfamily
WU11_RS13240	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
WU11_RS13260	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
WU11_RS13300	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WU11_RS13305	COG1116	anion transmembrane transporter activity
WU11_RS13315	COG1228	amidohydrolase
WU11_RS13330	COG0477	Major facilitator Superfamily
WU11_RS13340	COG3550	peptidyl-serine autophosphorylation
WU11_RS13355	COG0518	GMP synthase (glutamine-hydrolyzing) activity
WU11_RS13355	COG0519	Catalyzes the synthesis of GMP from XMP
WU11_RS13400	COG0420	3'-5' exonuclease activity
WU11_RS13405	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WU11_RS13435	COG0395	ABC-type sugar transport system, permease component
WU11_RS13445	COG3842	ATPase activity
WU11_RS13475	COG3181	Tripartite tricarboxylate transporter family receptor
WU11_RS13510	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WU11_RS13535	COG0602	queuosine metabolic process
WU11_RS13540	COG0720	synthase
WU11_RS13545	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
WU11_RS13550	COG0235	Class ii aldolase
WU11_RS13575	COG3210	domain, Protein
WU11_RS13575	COG3064	Membrane
WU11_RS13575	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
WU11_RS13580	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
WU11_RS13580	COG0047	phosphoribosylformylglycinamidine synthase activity
WU11_RS13585	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
WU11_RS13590	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
WU11_RS13590	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
WU11_RS13595	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
WU11_RS13615	COG3539	Fimbrial protein
WU11_RS13625	COG2050	protein possibly involved in aromatic compounds catabolism
WU11_RS13630	COG1024	Enoyl-CoA hydratase
WU11_RS13635	COG1012	belongs to the aldehyde dehydrogenase family
WU11_RS13645	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WU11_RS13650	COG2151	metal-sulfur cluster biosynthetic enzyme
WU11_RS13655	COG3396	Phenylacetate-CoA oxygenase
WU11_RS13660	COG3460	Phenylacetate-CoA oxygenase
WU11_RS13665	COG3396	Phenylacetate-CoA oxygenase
WU11_RS13670	COG3327	negative regulation of DNA-templated transcription, initiation
WU11_RS13680	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
WU11_RS13685	COG0501	Belongs to the peptidase M48B family
WU11_RS13690	COG1162	GTPase activity
WU11_RS13695	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WU11_RS13700	COG0601	transmembrane transport
WU11_RS13705	COG0747	negative chemotaxis
WU11_RS13750	COG0668	transmembrane transport
WU11_RS13755	COG0165	Argininosuccinate lyase
WU11_RS13775	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
WU11_RS13780	COG0303	'Molybdopterin
WU11_RS13785	COG0521	Mo-molybdopterin cofactor biosynthetic process
WU11_RS13800	COG0315	cyclic pyranopterin monophosphate synthase activity
WU11_RS13810	COG0412	Dienelactone hydrolase
WU11_RS13820	COG0678	peroxiredoxin activity
WU11_RS13830	COG0697	spore germination
WU11_RS13835	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
WU11_RS13860	COG0789	Transcriptional regulator
WU11_RS13880	COG1028	Short-chain dehydrogenase reductase Sdr
WU11_RS13890	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
WU11_RS13895	COG1845	cytochrome c oxidase, subunit III
WU11_RS13900	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
WU11_RS13910	COG0477	Major facilitator Superfamily
WU11_RS13940	COG3468	outer membrane autotransporter barrel domain protein
WU11_RS13950	COG1309	transcriptional regulator
WU11_RS13955	COG2271	Major facilitator Superfamily
WU11_RS13990	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
WU11_RS13990	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
WU11_RS13990	COG0506	proline dehydrogenase activity
WU11_RS14000	COG3008	intermembrane lipid transfer
WU11_RS14000	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
WU11_RS14005	COG2995	paraquat-inducible protein a
WU11_RS14010	COG0542	response to heat
WU11_RS14015	COG4953	penicillin-binding protein 1C
WU11_RS14025	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
WU11_RS14030	COG1278	Cold shock
WU11_RS14040	COG0183	Belongs to the thiolase family
WU11_RS14045	COG0038	chloride channel
WU11_RS14050	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
WU11_RS14055	COG1570	exodeoxyribonuclease VII activity
WU11_RS14065	COG0811	peptide transport
WU11_RS14070	COG0848	biopolymer transport protein
WU11_RS14075	COG1663	tetraacyldisaccharide 4'-kinase activity
WU11_RS14080	COG2835	tetraacyldisaccharide 4'-kinase activity
WU11_RS14085	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
WU11_RS14090	COG0563	adenylate kinase activity
WU11_RS14100	COG0728	peptidoglycan biosynthetic process
WU11_RS14110	COG0268	Binds directly to 16S ribosomal RNA
WU11_RS14140	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
WU11_RS14165	COG0436	Aminotransferase
WU11_RS14170	COG3737	Protein of unknown function (DUF498/DUF598)
WU11_RS14175	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
WU11_RS14180	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
WU11_RS14185	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
WU11_RS14195	COG0305	Participates in initiation and elongation during chromosome replication
WU11_RS14205	COG0359	binds to the 23S rRNA
WU11_RS14210	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
WU11_RS14215	COG2965	DNA replication, synthesis of RNA primer
WU11_RS14220	COG0360	Binds together with S18 to 16S ribosomal RNA
WU11_RS14225	COG1469	GTP cyclohydrolase I activity
WU11_RS14230	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
WU11_RS14235	COG0142	geranyltranstransferase activity
WU11_RS14240	COG1722	exodeoxyribonuclease VII activity
WU11_RS14250	COG3181	Tripartite tricarboxylate transporter family receptor
WU11_RS14270	COG2239	Acts as a magnesium transporter
WU11_RS14280	COG2855	membrane
WU11_RS14290	COG1473	amidohydrolase
WU11_RS14295	COG0318	PFAM AMP-dependent synthetase and ligase
WU11_RS14320	COG1501	Belongs to the glycosyl hydrolase 31 family
WU11_RS14325	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
WU11_RS14330	COG2011	ABC-type metal ion transport system permease component
WU11_RS14350	COG1454	alcohol dehydrogenase
WU11_RS14380	COG2186	Transcriptional regulator
WU11_RS14385	COG3181	Tripartite tricarboxylate transporter family receptor
WU11_RS14405	COG1175	transmembrane transport
WU11_RS14410	COG0395	ABC-type sugar transport system, permease component
WU11_RS14415	COG3842	ATPase activity
WU11_RS14420	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WU11_RS14430	COG1653	transport
WU11_RS14450	COG2818	Glycosylase
WU11_RS14455	COG2982	Protein involved in outer membrane biogenesis
WU11_RS14465	COG1309	transcriptional regulator
WU11_RS14470	COG1028	Short-chain dehydrogenase reductase Sdr
WU11_RS14530	COG0583	DNA-binding transcription factor activity
WU11_RS14535	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
WU11_RS14540	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WU11_RS14555	COG1028	Short-chain dehydrogenase reductase Sdr
WU11_RS14560	COG0477	Major facilitator Superfamily
WU11_RS14570	COG0583	DNA-binding transcription factor activity
WU11_RS14575	COG1448	Aminotransferase
WU11_RS14580	COG1418	mRNA catabolic process
WU11_RS14605	COG1063	alcohol dehydrogenase
WU11_RS14625	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WU11_RS14635	COG0318	PFAM AMP-dependent synthetase and ligase
WU11_RS14645	COG1522	sequence-specific DNA binding
WU11_RS14650	COG3181	Tripartite tricarboxylate transporter family receptor
WU11_RS14655	COG0307	riboflavin synthase, alpha
WU11_RS14660	COG0154	amidase activity
WU11_RS14680	COG2807	transmembrane transport
WU11_RS14685	COG0590	tRNA wobble adenosine to inosine editing
WU11_RS14695	COG0583	DNA-binding transcription factor activity
WU11_RS14710	COG1902	pentaerythritol trinitrate reductase activity
WU11_RS14730	COG0559	Belongs to the binding-protein-dependent transport system permease family
WU11_RS14735	COG0251	oxidation-reduction process
WU11_RS14740	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
WU11_RS14750	COG1414	Transcriptional regulator
WU11_RS14755	COG1028	Short-chain dehydrogenase reductase Sdr
WU11_RS14770	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WU11_RS14785	COG1024	Enoyl-CoA hydratase
WU11_RS14790	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU11_RS14795	COG0154	amidase activity
WU11_RS14835	COG3909	cytochrome
WU11_RS14840	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
WU11_RS14845	COG0625	glutathione transferase activity
WU11_RS14850	COG0730	response to heat
WU11_RS14855	COG0482	sulfurtransferase activity
WU11_RS14860	COG0583	DNA-binding transcription factor activity
WU11_RS14880	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
WU11_RS14905	COG2819	hydrolase of the alpha beta superfamily
WU11_RS14910	COG0247	lactate metabolic process
WU11_RS14915	COG0277	FAD linked oxidase domain protein
WU11_RS14920	COG0277	FAD linked oxidase domain protein
WU11_RS14925	COG0277	FAD linked oxidase domain protein
WU11_RS14930	COG3210	domain, Protein
WU11_RS14930	COG3210	domain, Protein
WU11_RS14930	COG3064	Membrane
WU11_RS14930	COG3064	Membrane
WU11_RS14930	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
WU11_RS14930	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
WU11_RS14935	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
WU11_RS14940	COG0312	modulator of DNA gyrase
WU11_RS14975	COG1666	GTP binding
WU11_RS15020	COG3220	belongs to the UPF0276 family
WU11_RS15040	COG0640	Transcriptional regulator
WU11_RS15045	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
WU11_RS15050	COG1845	cytochrome c oxidase, subunit III
WU11_RS15055	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
WU11_RS15065	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
WU11_RS15100	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU11_RS15105	COG0583	DNA-binding transcription factor activity
WU11_RS15135	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
WU11_RS15135	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
WU11_RS15150	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
WU11_RS15155	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
WU11_RS15165	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
WU11_RS15180	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
WU11_RS15185	COG0316	Belongs to the HesB IscA family
WU11_RS15195	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
WU11_RS15200	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
WU11_RS15205	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
WU11_RS15210	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
WU11_RS15215	COG0312	modulator of DNA gyrase
WU11_RS15220	COG3028	Belongs to the UPF0307 family
WU11_RS15235	COG1116	anion transmembrane transporter activity
WU11_RS15240	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WU11_RS15245	COG1335	isochorismatase
WU11_RS15250	COG0346	lactoylglutathione lyase activity
WU11_RS15255	COG0513	Belongs to the DEAD box helicase family
WU11_RS15260	COG3069	C4-dicarboxylate transmembrane transporter activity
WU11_RS15265	COG1802	Transcriptional regulator
WU11_RS15280	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WU11_RS15280	COG1042	CoA-binding domain protein
WU11_RS15280	COG0045	succinate-CoA ligase (ADP-forming) activity
WU11_RS15285	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
WU11_RS15300	COG1522	sequence-specific DNA binding
WU11_RS15335	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
WU11_RS15340	COG1696	Membrane protein involved in D-alanine export
WU11_RS15365	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WU11_RS15375	COG2264	protein methyltransferase activity
WU11_RS15380	COG0439	Biotin carboxylase
WU11_RS15385	COG0511	ligase activity, forming carbon-carbon bonds
WU11_RS15390	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
WU11_RS15395	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
WU11_RS15400	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
WU11_RS15405	COG3150	esterase
WU11_RS15410	COG0557	exoribonuclease II activity
WU11_RS15420	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
WU11_RS15440	COG1522	sequence-specific DNA binding
WU11_RS15445	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WU11_RS15450	COG1028	Short-chain dehydrogenase reductase Sdr
WU11_RS15470	COG0653	protein targeting
WU11_RS15475	COG0739	heme binding
WU11_RS15485	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
WU11_RS15490	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
WU11_RS15500	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
WU11_RS15505	COG1181	Belongs to the D-alanine--D-alanine ligase family
WU11_RS15510	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
WU11_RS15515	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
WU11_RS15525	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
WU11_RS15530	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
WU11_RS15535	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
WU11_RS15545	COG3116	cell division
WU11_RS15550	COG0275	rRNA processing
WU11_RS15555	COG2001	Belongs to the MraZ family
WU11_RS15565	COG0488	(ABC) transporter
WU11_RS15570	COG0418	dihydroorotase activity
WU11_RS15575	COG1473	amidohydrolase
WU11_RS15625	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
WU11_RS15630	COG4654	Cytochrome c, class I
WU11_RS15635	COG0129	dihydroxy-acid dehydratase activity
WU11_RS15640	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
WU11_RS15690	COG2084	Dehydrogenase
WU11_RS15695	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
WU11_RS15705	COG2096	Adenosyltransferase
WU11_RS15715	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
WU11_RS15720	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
WU11_RS15730	COG0523	cobalamin synthesis protein
WU11_RS15735	COG0735	belongs to the Fur family
WU11_RS15755	COG0803	Belongs to the bacterial solute-binding protein 9 family
WU11_RS15765	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
WU11_RS15775	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
WU11_RS15785	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
WU11_RS15790	COG1560	Kdo2-lipid A biosynthetic process
WU11_RS15800	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
WU11_RS15815	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
WU11_RS15820	COG1950	PFAM Membrane protein of
WU11_RS15835	COG0583	DNA-binding transcription factor activity
WU11_RS15845	COG0477	Major facilitator Superfamily
WU11_RS15860	COG0617	tRNA 3'-terminal CCA addition
WU11_RS15870	COG0513	Belongs to the DEAD box helicase family
WU11_RS15875	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
WU11_RS15890	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WU11_RS15895	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
WU11_RS15955	COG1280	lysine exporter protein (LysE YggA)
WU11_RS15970	COG0405	Gamma-glutamyltransferase
WU11_RS15980	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WU11_RS16010	COG1309	transcriptional regulator
WU11_RS16020	COG3181	Tripartite tricarboxylate transporter family receptor
WU11_RS16030	COG0745	RESPONSE REGULATOR receiver
WU11_RS16095	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
WU11_RS16120	COG0582	viral genome integration into host DNA
WU11_RS16125	COG0012	GTP binding
WU11_RS16135	COG0193	aminoacyl-tRNA hydrolase activity
WU11_RS16140	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
WU11_RS16145	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
WU11_RS16155	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
WU11_RS16160	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
WU11_RS16170	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
WU11_RS16195	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
WU11_RS16205	COG1368	sulfuric ester hydrolase activity
WU11_RS16210	COG0642	Histidine kinase
WU11_RS16215	COG0745	RESPONSE REGULATOR receiver
WU11_RS16220	COG0277	FAD linked oxidase domain protein
WU11_RS16235	COG0166	Belongs to the GPI family
WU11_RS16240	COG0438	transferase activity, transferring glycosyl groups
WU11_RS16245	COG0438	transferase activity, transferring glycosyl groups
WU11_RS16260	COG0438	transferase activity, transferring glycosyl groups
WU11_RS16275	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
WU11_RS16280	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
WU11_RS16285	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
WU11_RS16295	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
WU11_RS16305	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WU11_RS16310	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
WU11_RS16320	COG0747	negative chemotaxis
WU11_RS16325	COG0601	transmembrane transport
WU11_RS16330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WU11_RS16350	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
WU11_RS16355	COG0830	nickel cation binding
WU11_RS16365	COG0804	urea catabolic process
WU11_RS16370	COG0832	Belongs to the urease beta subunit family
WU11_RS16380	COG0831	urea catabolic process
WU11_RS16385	COG0829	nickel cation binding
WU11_RS16395	COG0633	Ferredoxin
WU11_RS16410	COG2188	Transcriptional regulator
WU11_RS16435	COG2719	SpoVR family
WU11_RS16440	COG2718	Belongs to the UPF0229 family
WU11_RS16455	COG1028	Short-chain dehydrogenase reductase Sdr
WU11_RS16460	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU11_RS16475	COG1960	acyl-CoA dehydrogenase activity
WU11_RS16520	COG0183	Belongs to the thiolase family
WU11_RS16525	COG2030	dehydratase
WU11_RS16580	COG0328	RNA-DNA hybrid ribonuclease activity
WU11_RS16585	COG2226	methyltransferase
WU11_RS16590	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WU11_RS16595	COG0741	lytic transglycosylase activity
WU11_RS16595	COG1388	LysM domain
WU11_RS16615	COG2979	Protein of unknown function (DUF533)
WU11_RS16650	COG1271	oxidase subunit
WU11_RS16655	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
WU11_RS16660	COG0850	regulation of cytokinetic process
WU11_RS16665	COG2894	cell division
WU11_RS16670	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
WU11_RS16690	COG0488	(ABC) transporter
WU11_RS16705	COG0601	transmembrane transport
WU11_RS16715	COG1215	transferase activity, transferring glycosyl groups
WU11_RS16730	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
WU11_RS16740	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
WU11_RS16760	COG0318	PFAM AMP-dependent synthetase and ligase
WU11_RS16765	COG2188	Transcriptional regulator
WU11_RS16770	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
WU11_RS16775	COG2814	Major facilitator Superfamily
WU11_RS16785	COG0259	pyridoxamine-phosphate oxidase activity
WU11_RS16790	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
WU11_RS16805	COG0583	DNA-binding transcription factor activity
WU11_RS16810	COG1960	acyl-CoA dehydrogenase activity
WU11_RS16830	COG0134	indole-3-glycerol-phosphate synthase activity
WU11_RS16835	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
WU11_RS16840	COG0512	Glutamine amidotransferase of anthranilate synthase
WU11_RS16850	COG0546	phosphoglycolate phosphatase activity
WU11_RS16855	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
WU11_RS16860	COG2967	ApaG domain
WU11_RS16865	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
WU11_RS16870	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WU11_RS16875	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
WU11_RS16880	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
WU11_RS16890	COG0037	tRNA processing
WU11_RS16900	COG3634	alkyl hydroperoxide reductase activity
WU11_RS16905	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WU11_RS16910	COG1024	Enoyl-CoA hydratase
WU11_RS16935	COG0356	it plays a direct role in the translocation of protons across the membrane
WU11_RS16945	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
WU11_RS16950	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
WU11_RS16955	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
WU11_RS16960	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
WU11_RS16965	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
WU11_RS16970	COG0355	proton-transporting ATP synthase activity, rotational mechanism
WU11_RS16980	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
WU11_RS16985	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
WU11_RS16990	COG0210	DNA helicase
WU11_RS17000	COG2195	Cleaves the N-terminal amino acid of tripeptides
WU11_RS17010	COG4172	Belongs to the ABC transporter superfamily
WU11_RS17015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WU11_RS17020	COG0601	transmembrane transport
WU11_RS17040	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
WU11_RS17045	COG1024	Enoyl-CoA hydratase
WU11_RS17050	COG1024	Enoyl-CoA hydratase
WU11_RS17075	COG1250	3-hydroxyacyl-CoA dehydrogenase
WU11_RS17105	COG2132	Multicopper oxidase
WU11_RS17115	COG1024	Enoyl-CoA hydratase
WU11_RS17115	COG1250	3-hydroxyacyl-CoA dehydrogenase
WU11_RS17125	COG1414	Transcriptional regulator
WU11_RS17135	COG0154	amidase activity
WU11_RS17165	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WU11_RS17170	COG3568	Endonuclease Exonuclease Phosphatase
WU11_RS17175	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
WU11_RS17210	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
WU11_RS17220	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
WU11_RS17235	COG1137	ATPase activity
WU11_RS17240	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
WU11_RS17250	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
WU11_RS17255	COG2010	Cytochrome c
WU11_RS17255	COG1529	Aldehyde oxidase and xanthine dehydrogenase
WU11_RS17265	COG1660	Displays ATPase and GTPase activities
WU11_RS17270	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
WU11_RS17305	COG3181	Tripartite tricarboxylate transporter family receptor
WU11_RS17315	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
WU11_RS17320	COG2890	protein-(glutamine-N5) methyltransferase activity
WU11_RS17325	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
WU11_RS17330	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
WU11_RS17380	COG1960	acyl-CoA dehydrogenase activity
WU11_RS17390	COG0183	Belongs to the thiolase family
WU11_RS17395	COG1522	sequence-specific DNA binding
WU11_RS17400	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
WU11_RS17420	COG1024	Enoyl-CoA hydratase
WU11_RS17435	COG0604	alcohol dehydrogenase
WU11_RS17440	COG2072	flavoprotein involved in K transport
WU11_RS17455	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
WU11_RS17465	COG1960	acyl-CoA dehydrogenase activity
WU11_RS17470	COG1960	acyl-CoA dehydrogenase activity
WU11_RS17475	COG0277	FAD linked oxidase domain protein
WU11_RS17485	COG3181	Tripartite tricarboxylate transporter family receptor
WU11_RS17510	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WU11_RS17520	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU11_RS17525	COG3181	Tripartite tricarboxylate transporter family receptor
WU11_RS17530	COG1960	acyl-CoA dehydrogenase activity
WU11_RS17550	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
WU11_RS17555	COG1024	Enoyl-CoA hydratase
WU11_RS17560	COG1960	acyl-CoA dehydrogenase activity
WU11_RS17580	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
WU11_RS17585	COG0022	dehydrogenase e1 component
WU11_RS17590	COG1024	Enoyl-CoA hydratase
WU11_RS17595	COG0508	dehydrogenase complex catalyzes the overall conversion of
WU11_RS17615	COG0683	leucine binding
WU11_RS17620	COG0559	Belongs to the binding-protein-dependent transport system permease family
WU11_RS17625	COG0411	ABC transporter
WU11_RS17635	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WU11_RS17650	COG3181	Tripartite tricarboxylate transporter family receptor
WU11_RS17680	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
WU11_RS17685	COG0793	Belongs to the peptidase S41A family
WU11_RS17690	COG4942	peptidase
WU11_RS17695	COG0588	phosphoglycerate mutase activity
WU11_RS17700	COG1054	Belongs to the UPF0176 family
WU11_RS17705	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
WU11_RS17710	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
WU11_RS17715	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
WU11_RS17720	COG3181	Tripartite tricarboxylate transporter family receptor
WU11_RS17735	COG2226	methyltransferase
WU11_RS17740	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
WU11_RS17755	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WU11_RS17760	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
WU11_RS17785	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
WU11_RS17810	COG1335	isochorismatase
WU11_RS17815	COG2309	aminopeptidase activity
WU11_RS17820	COG0596	Alpha beta hydrolase
WU11_RS17825	COG3473	Maleate cis-trans isomerase
WU11_RS17835	COG2068	MobA-Related Protein
WU11_RS17860	COG2204	response regulator
WU11_RS17865	COG5000	phosphorelay sensor kinase activity
WU11_RS17875	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
WU11_RS17875	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
WU11_RS17885	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
WU11_RS17915	COG0583	DNA-binding transcription factor activity
WU11_RS17930	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
WU11_RS17935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WU11_RS17940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WU11_RS17955	COG0758	DNA mediated transformation
WU11_RS17960	COG1522	sequence-specific DNA binding
WU11_RS17970	COG0242	peptide deformylase activity
WU11_RS17985	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
WU11_RS17995	COG0546	phosphoglycolate phosphatase activity
WU11_RS18015	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
WU11_RS18020	COG1942	4-Oxalocrotonate Tautomerase
WU11_RS18025	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WU11_RS18050	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
WU11_RS18070	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WU11_RS18075	COG1024	Enoyl-CoA hydratase
WU11_RS18080	COG1414	Transcriptional regulator
WU11_RS18085	COG0318	PFAM AMP-dependent synthetase and ligase
WU11_RS18090	COG3181	Tripartite tricarboxylate transporter family receptor
WU11_RS18120	COG0583	DNA-binding transcription factor activity
WU11_RS18135	COG3422	double-strand break repair
WU11_RS18140	COG0330	HflC and HflK could
WU11_RS18150	COG0251	oxidation-reduction process
WU11_RS18195	COG3723	Recombinational DNA repair protein, rece pathway
WU11_RS18230	COG0582	viral genome integration into host DNA
WU11_RS18255	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
WU11_RS18265	COG0706	membrane insertase activity
WU11_RS18270	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
WU11_RS18275	COG0594	ribonuclease P activity
WU11_RS18280	COG0230	Belongs to the bacterial ribosomal protein bL34 family
WU11_RS18285	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
WU11_RS18300	COG1414	Transcriptional regulator
WU11_RS18305	COG0154	amidase activity
WU11_RS18320	COG1304	FMN binding
WU11_RS18340	COG1960	acyl-CoA dehydrogenase activity
WU11_RS18360	COG1960	acyl-CoA dehydrogenase activity
WU11_RS18375	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
WU11_RS18390	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
WU11_RS18395	COG3181	Tripartite tricarboxylate transporter family receptor
WU11_RS18405	COG2358	TRAP transporter, solute receptor (TAXI family
WU11_RS18415	COG1629	transport
WU11_RS18420	COG2922	Belongs to the Smg family
WU11_RS18445	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
WU11_RS18450	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WU11_RS18455	COG1028	Short-chain dehydrogenase reductase Sdr
WU11_RS18460	COG1012	belongs to the aldehyde dehydrogenase family
WU11_RS18470	COG0028	Belongs to the TPP enzyme family
WU11_RS18475	COG1522	sequence-specific DNA binding
WU11_RS18480	COG3781	membrane
WU11_RS18490	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
WU11_RS18510	COG4206	TonB-dependent receptor
WU11_RS18515	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
WU11_RS18520	COG2022	thiamine diphosphate biosynthetic process
WU11_RS18525	COG0351	phosphomethylpyrimidine kinase
WU11_RS18530	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
WU11_RS18545	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
WU11_RS18555	COG0628	permease
WU11_RS18565	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
WU11_RS18575	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
WU11_RS18580	COG0049	tRNA binding
WU11_RS18585	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
WU11_RS18590	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
WU11_RS18595	COG0051	transcription antitermination factor activity, RNA binding
WU11_RS18600	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
WU11_RS18605	COG0088	Forms part of the polypeptide exit tunnel
WU11_RS18610	COG0089	rRNA binding
WU11_RS18615	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
WU11_RS18620	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
WU11_RS18625	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
WU11_RS18630	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
WU11_RS18635	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
WU11_RS18640	COG0255	Belongs to the universal ribosomal protein uL29 family
WU11_RS18645	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
WU11_RS18665	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
WU11_RS18670	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
WU11_RS18675	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
WU11_RS18680	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
WU11_RS18685	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
WU11_RS18690	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
WU11_RS18695	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
WU11_RS18700	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
WU11_RS18705	COG1841	ribosomal large subunit assembly
WU11_RS18710	COG0200	Binds to the 23S rRNA
WU11_RS18715	COG0201	protein transport
WU11_RS18720	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
WU11_RS18725	COG0257	Belongs to the bacterial ribosomal protein bL36 family
WU11_RS18730	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
WU11_RS18735	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
WU11_RS18740	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
WU11_RS18745	COG0202	RNA polymerase activity
WU11_RS18750	COG0203	ribosomal protein L17
WU11_RS18755	COG0537	adenosine 5'-monophosphoramidase activity
WU11_RS18760	COG1324	tolerance protein
WU11_RS18765	COG4232	protein-disulfide reductase activity
WU11_RS18780	COG0218	Necessary for normal cell division and for the maintenance of normal septation
WU11_RS18790	COG1333	cytochrome c biogenesis protein
WU11_RS18795	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
WU11_RS18810	COG1965	Belongs to the frataxin family
WU11_RS18820	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
WU11_RS18825	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
WU11_RS18830	COG0232	Belongs to the dGTPase family. Type 2 subfamily
WU11_RS18845	COG2814	Major facilitator Superfamily
WU11_RS18850	COG0629	single-stranded DNA binding
WU11_RS18890	COG0402	S-adenosylhomocysteine deaminase activity
WU11_RS18900	COG0438	transferase activity, transferring glycosyl groups
WU11_RS18920	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WU11_RS18945	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
WU11_RS18950	COG2186	Transcriptional regulator
WU11_RS18970	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WU11_RS18975	COG1956	GAF domain-containing protein
WU11_RS18980	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WU11_RS18995	COG1652	LysM domain
WU11_RS19010	COG0220	tRNA (guanine-N7-)-methyltransferase activity
WU11_RS19025	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
WU11_RS19055	COG3181	Tripartite tricarboxylate transporter family receptor
WU11_RS19070	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WU11_RS19085	COG1024	Enoyl-CoA hydratase
WU11_RS19100	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU11_RS19105	COG1309	transcriptional regulator
WU11_RS19110	COG2816	NAD+ diphosphatase activity
WU11_RS19115	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WU11_RS19200	COG2814	Major facilitator Superfamily
WU11_RS19205	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
WU11_RS19225	COG1999	signal sequence binding
WU11_RS19230	COG0109	protoheme IX farnesyltransferase activity
WU11_RS19270	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
WU11_RS19290	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
WU11_RS19295	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
WU11_RS19305	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
WU11_RS19310	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
WU11_RS19320	COG0067	glutamate synthase
WU11_RS19320	COG0069	glutamate synthase activity
WU11_RS19320	COG0070	glutamate synthase
WU11_RS19330	COG3047	cAMP biosynthetic process
WU11_RS19340	COG1127	ABC transporter
WU11_RS19345	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
WU11_RS19350	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
WU11_RS19355	COG2853	Lipoprotein
WU11_RS19365	COG1131	(ABC) transporter
WU11_RS19370	COG0842	Transport permease protein
WU11_RS19380	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
WU11_RS19385	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
WU11_RS19390	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
WU11_RS19395	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
WU11_RS19400	COG0131	Imidazoleglycerol-phosphate dehydratase
WU11_RS19405	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
WU11_RS19410	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
WU11_RS19415	COG0107	imidazoleglycerol-phosphate synthase activity
WU11_RS19420	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
WU11_RS19425	COG0140	phosphoribosyl-ATP diphosphatase activity
WU11_RS19430	COG0537	adenosine 5'-monophosphoramidase activity
WU11_RS19435	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
WU11_RS19440	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
WU11_RS19455	COG3181	Tripartite tricarboxylate transporter family receptor
WU11_RS19490	COG3702	type iv secretory pathway
WU11_RS19495	COG3451	type IV secretory pathway VirB4
WU11_RS19510	COG3736	Type IV secretory pathway, component VirB8
WU11_RS19515	COG3504	Conjugal transfer protein
WU11_RS19520	COG2948	multi-organism process
WU11_RS19525	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
WU11_RS19535	COG0697	spore germination
WU11_RS19555	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
WU11_RS19560	COG0747	negative chemotaxis
WU11_RS19565	COG0601	transmembrane transport
WU11_RS19570	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WU11_RS19575	COG0444	Belongs to the ABC transporter superfamily
WU11_RS19585	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
WU11_RS19595	COG0494	nUDIX hydrolase
WU11_RS19635	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
WU11_RS19640	COG0237	dephospho-CoA kinase activity
WU11_RS19645	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
WU11_RS19660	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
WU11_RS19665	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
WU11_RS19675	COG0477	Major facilitator Superfamily
WU11_RS19680	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
WU11_RS19695	COG1126	abc transporter atp-binding protein
WU11_RS19700	COG0765	amino acid transport
WU11_RS19705	COG4597	amino acid ABC transporter
WU11_RS19710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WU11_RS19715	COG2884	Cell division ATP-binding protein ftsE
WU11_RS19720	COG2177	Part of the ABC transporter FtsEX involved in
WU11_RS19725	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
WU11_RS19735	COG1194	a g-specific adenine glycosylase
WU11_RS19745	COG2226	methyltransferase
WU11_RS19755	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU11_RS19760	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU11_RS19775	COG1024	Enoyl-CoA hydratase
WU11_RS19795	COG1024	Enoyl-CoA hydratase
WU11_RS19800	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU11_RS19805	COG3181	Tripartite tricarboxylate transporter family receptor
WU11_RS19815	COG0753	catalase activity
WU11_RS19820	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WU11_RS19825	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
WU11_RS19835	COG2175	clavaminate synthase activity
WU11_RS19840	COG1473	amidohydrolase
WU11_RS19845	COG4608	Belongs to the ABC transporter superfamily
WU11_RS19850	COG0444	Belongs to the ABC transporter superfamily
WU11_RS19865	COG0747	negative chemotaxis
WU11_RS19870	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
WU11_RS19905	COG0436	Aminotransferase
WU11_RS19910	COG1278	Cold shock