locus-tag	class	description
ADU62_RS00005	COG0445	tRNA wobble uridine modification
ADU62_RS00010	COG0357	Ribosomal RNA small subunit methyltransferase G
ADU62_RS00015	COG1192	Involved in chromosome partitioning
ADU62_RS00025	COG1475	DNA binding
ADU62_RS00030	COG0252	asparaginase activity
ADU62_RS00055	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ADU62_RS00065	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ADU62_RS00075	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ADU62_RS00080	COG0081	regulation of translation
ADU62_RS00085	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ADU62_RS00090	COG0222	ribosome binding
ADU62_RS00095	COG0085	RNA polymerase activity
ADU62_RS00100	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ADU62_RS00140	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ADU62_RS00165	COG1024	Enoyl-CoA hydratase
ADU62_RS00185	COG0752	glycyl-tRNA synthetase alpha subunit
ADU62_RS00190	COG0751	glycine-tRNA ligase activity
ADU62_RS00195	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ADU62_RS00200	COG0204	Acyl-transferase
ADU62_RS00215	COG0242	peptide deformylase activity
ADU62_RS00250	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ADU62_RS00265	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ADU62_RS00270	COG2813	Specifically methylates the guanine in position
ADU62_RS00270	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ADU62_RS00285	COG2223	nitrite transmembrane transporter activity
ADU62_RS00295	COG1794	racemase activity, acting on amino acids and derivatives
ADU62_RS00300	COG1126	abc transporter atp-binding protein
ADU62_RS00305	COG0765	amino acid transport
ADU62_RS00310	COG0765	amino acid transport
ADU62_RS00315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ADU62_RS00380	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ADU62_RS00410	COG0326	Molecular chaperone. Has ATPase activity
ADU62_RS00415	COG0625	glutathione transferase activity
ADU62_RS00430	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ADU62_RS00435	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ADU62_RS00465	COG0438	transferase activity, transferring glycosyl groups
ADU62_RS00470	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ADU62_RS00475	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ADU62_RS00505	COG0859	PFAM glycosyl transferase family 9
ADU62_RS00520	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ADU62_RS00530	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ADU62_RS00535	COG1127	ABC transporter
ADU62_RS00555	COG1686	Belongs to the peptidase S11 family
ADU62_RS00565	COG2921	Belongs to the UPF0250 family
ADU62_RS00570	COG0321	lipoyl(octanoyl) transferase activity
ADU62_RS00575	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ADU62_RS00610	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ADU62_RS00620	COG0018	arginyl-trna synthetase
ADU62_RS00640	COG0395	ABC-type sugar transport system, permease component
ADU62_RS00645	COG1175	transmembrane transport
ADU62_RS00650	COG1653	transport
ADU62_RS00655	COG3842	ATPase activity
ADU62_RS00660	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ADU62_RS00670	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ADU62_RS00690	COG1609	Transcriptional regulator
ADU62_RS00700	COG0154	amidase activity
ADU62_RS00705	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ADU62_RS00715	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ADU62_RS00725	COG0583	DNA-binding transcription factor activity
ADU62_RS00740	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ADU62_RS00745	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ADU62_RS00760	COG1802	Transcriptional regulator
ADU62_RS00775	COG1024	Enoyl-CoA hydratase
ADU62_RS00785	COG3181	Tripartite tricarboxylate transporter family receptor
ADU62_RS00800	COG1984	allophanate hydrolase subunit 2
ADU62_RS00805	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ADU62_RS00815	COG0583	DNA-binding transcription factor activity
ADU62_RS00820	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ADU62_RS00830	COG5002	protein histidine kinase activity
ADU62_RS00840	COG5002	protein histidine kinase activity
ADU62_RS00845	COG0745	RESPONSE REGULATOR receiver
ADU62_RS00850	COG2226	methyltransferase
ADU62_RS00865	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ADU62_RS00885	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
ADU62_RS00895	COG0513	Belongs to the DEAD box helicase family
ADU62_RS00900	COG1280	lysine exporter protein (LysE YggA)
ADU62_RS00905	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ADU62_RS00940	COG1054	Belongs to the UPF0176 family
ADU62_RS00945	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ADU62_RS00945	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ADU62_RS00955	COG0489	protein tyrosine kinase activity
ADU62_RS00970	COG0717	Belongs to the dCTP deaminase family
ADU62_RS01000	COG2081	HI0933 family
ADU62_RS01010	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ADU62_RS01020	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ADU62_RS01025	COG0509	glycine decarboxylation via glycine cleavage system
ADU62_RS01030	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ADU62_RS01030	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ADU62_RS01070	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ADU62_RS01085	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ADU62_RS01095	COG1414	Transcriptional regulator
ADU62_RS01100	COG1028	Short-chain dehydrogenase reductase Sdr
ADU62_RS01105	COG2031	fatty acid transporter
ADU62_RS01110	COG1250	3-hydroxyacyl-CoA dehydrogenase
ADU62_RS01120	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ADU62_RS01125	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ADU62_RS01135	COG4257	antibiotic catabolic process
ADU62_RS01160	COG1012	belongs to the aldehyde dehydrogenase family
ADU62_RS01165	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ADU62_RS01170	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ADU62_RS01195	COG1028	Short-chain dehydrogenase reductase Sdr
ADU62_RS01205	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ADU62_RS01220	COG2188	Transcriptional regulator
ADU62_RS01225	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ADU62_RS01250	COG0617	tRNA 3'-terminal CCA addition
ADU62_RS01265	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ADU62_RS01270	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ADU62_RS01275	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ADU62_RS01280	COG0586	Pfam SNARE associated Golgi protein
ADU62_RS01285	COG0860	N-Acetylmuramoyl-L-alanine amidase
ADU62_RS01290	COG0802	atpase or kinase
ADU62_RS01295	COG0114	fumarate hydratase activity
ADU62_RS01305	COG3181	Tripartite tricarboxylate transporter family receptor
ADU62_RS01315	COG0405	Gamma-glutamyltransferase
ADU62_RS01320	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ADU62_RS01330	COG1960	acyl-CoA dehydrogenase activity
ADU62_RS01355	COG1294	oxidase, subunit
ADU62_RS01365	COG4988	ABC transporter
ADU62_RS01370	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ADU62_RS01375	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ADU62_RS01390	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ADU62_RS01420	COG2969	positive regulation of protein catabolic process
ADU62_RS01425	COG0625	glutathione transferase activity
ADU62_RS01430	COG2857	Cytochrome c1
ADU62_RS01435	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ADU62_RS01440	COG0723	plastoquinol--plastocyanin reductase activity
ADU62_RS01445	COG1970	mechanosensitive ion channel activity
ADU62_RS01450	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ADU62_RS01465	COG2808	Putative FMN-binding domain
ADU62_RS01470	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ADU62_RS01475	COG0747	negative chemotaxis
ADU62_RS01480	COG0657	acetylesterase activity
ADU62_RS01490	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ADU62_RS01495	COG2207	Transcriptional regulator
ADU62_RS01500	COG0129	dihydroxy-acid dehydratase activity
ADU62_RS01505	COG2814	Major facilitator Superfamily
ADU62_RS01510	COG0583	DNA-binding transcription factor activity
ADU62_RS01520	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
ADU62_RS01590	COG1024	Enoyl-CoA hydratase
ADU62_RS01595	COG1960	acyl-CoA dehydrogenase activity
ADU62_RS01620	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ADU62_RS01625	COG0352	thiamine-phosphate diphosphorylase activity
ADU62_RS01640	COG1678	Uncharacterized ACR, COG1678
ADU62_RS01645	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ADU62_RS01650	COG0540	Belongs to the ATCase OTCase family
ADU62_RS01665	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ADU62_RS01675	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ADU62_RS01710	COG1234	tRNA 3'-trailer cleavage
ADU62_RS01730	COG3064	Membrane
ADU62_RS01760	COG1683	Conserved Protein
ADU62_RS01765	COG1120	ATPase activity
ADU62_RS01770	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ADU62_RS01775	COG4558	Periplasmic binding protein
ADU62_RS01780	COG3720	iron ion transport
ADU62_RS01790	COG3712	iron ion homeostasis
ADU62_RS01795	COG1595	DNA-templated transcription, initiation
ADU62_RS01830	COG1802	Transcriptional regulator
ADU62_RS01840	COG3069	C4-dicarboxylate transmembrane transporter activity
ADU62_RS01850	COG1012	belongs to the aldehyde dehydrogenase family
ADU62_RS01885	COG2860	membrane
ADU62_RS01890	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ADU62_RS01895	COG0708	Exodeoxyribonuclease III
ADU62_RS01900	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ADU62_RS01905	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ADU62_RS01910	COG0154	amidase activity
ADU62_RS01915	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ADU62_RS01920	COG1077	Cell shape determining protein MreB Mrl
ADU62_RS01925	COG1792	Involved in formation and maintenance of cell shape
ADU62_RS01935	COG0768	penicillin binding
ADU62_RS01940	COG0772	Belongs to the SEDS family
ADU62_RS01945	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ADU62_RS01950	COG0471	metal ion transport
ADU62_RS01955	COG1309	transcriptional regulator
ADU62_RS01965	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ADU62_RS01980	COG2823	Periplasmic or secreted lipoprotein
ADU62_RS01985	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ADU62_RS02000	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ADU62_RS02020	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ADU62_RS02030	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ADU62_RS02050	COG0492	ferredoxin-NADP+ reductase activity
ADU62_RS02060	COG3181	Tripartite tricarboxylate transporter family receptor
ADU62_RS02065	COG1024	Enoyl-CoA hydratase
ADU62_RS02065	COG1250	3-hydroxyacyl-CoA dehydrogenase
ADU62_RS02070	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ADU62_RS02075	COG0028	Belongs to the TPP enzyme family
ADU62_RS02100	COG3181	Tripartite tricarboxylate transporter family receptor
ADU62_RS02115	COG0697	spore germination
ADU62_RS02145	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ADU62_RS02150	COG0463	Glycosyl transferase, family 2
ADU62_RS02170	COG0786	glutamate:sodium symporter activity
ADU62_RS02180	COG2031	fatty acid transporter
ADU62_RS02195	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ADU62_RS02200	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ADU62_RS02225	COG3181	Tripartite tricarboxylate transporter family receptor
ADU62_RS02235	COG0277	FAD linked oxidase domain protein
ADU62_RS02240	COG1960	acyl-CoA dehydrogenase activity
ADU62_RS02245	COG1960	acyl-CoA dehydrogenase activity
ADU62_RS02255	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ADU62_RS02270	COG2072	flavoprotein involved in K transport
ADU62_RS02275	COG0604	alcohol dehydrogenase
ADU62_RS02290	COG1024	Enoyl-CoA hydratase
ADU62_RS02310	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ADU62_RS02315	COG1522	sequence-specific DNA binding
ADU62_RS02320	COG0183	Belongs to the thiolase family
ADU62_RS02330	COG1960	acyl-CoA dehydrogenase activity
ADU62_RS02375	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ADU62_RS02380	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ADU62_RS02385	COG2890	protein-(glutamine-N5) methyltransferase activity
ADU62_RS02390	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ADU62_RS02400	COG3181	Tripartite tricarboxylate transporter family receptor
ADU62_RS02435	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ADU62_RS02440	COG1660	Displays ATPase and GTPase activities
ADU62_RS02450	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ADU62_RS02450	COG2010	Cytochrome c
ADU62_RS02455	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
ADU62_RS02465	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ADU62_RS02470	COG1137	ATPase activity
ADU62_RS02485	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ADU62_RS02495	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ADU62_RS02530	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ADU62_RS02535	COG3568	Endonuclease Exonuclease Phosphatase
ADU62_RS02540	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ADU62_RS02570	COG0154	amidase activity
ADU62_RS02580	COG1414	Transcriptional regulator
ADU62_RS02590	COG1250	3-hydroxyacyl-CoA dehydrogenase
ADU62_RS02590	COG1024	Enoyl-CoA hydratase
ADU62_RS02600	COG2132	Multicopper oxidase
ADU62_RS02630	COG1250	3-hydroxyacyl-CoA dehydrogenase
ADU62_RS02655	COG1024	Enoyl-CoA hydratase
ADU62_RS02660	COG1024	Enoyl-CoA hydratase
ADU62_RS02665	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ADU62_RS02685	COG0601	transmembrane transport
ADU62_RS02690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ADU62_RS02695	COG4172	Belongs to the ABC transporter superfamily
ADU62_RS02705	COG2195	Cleaves the N-terminal amino acid of tripeptides
ADU62_RS02715	COG0210	DNA helicase
ADU62_RS02720	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ADU62_RS02725	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ADU62_RS02735	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ADU62_RS02740	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ADU62_RS02745	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ADU62_RS02750	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ADU62_RS02755	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ADU62_RS02760	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ADU62_RS02770	COG0356	it plays a direct role in the translocation of protons across the membrane
ADU62_RS02795	COG1024	Enoyl-CoA hydratase
ADU62_RS02800	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ADU62_RS02805	COG3634	alkyl hydroperoxide reductase activity
ADU62_RS02815	COG0037	tRNA processing
ADU62_RS02825	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ADU62_RS02830	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ADU62_RS02835	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ADU62_RS02840	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ADU62_RS02845	COG2967	ApaG domain
ADU62_RS02850	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ADU62_RS02855	COG0546	phosphoglycolate phosphatase activity
ADU62_RS02865	COG0512	Glutamine amidotransferase of anthranilate synthase
ADU62_RS02870	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ADU62_RS02875	COG0134	indole-3-glycerol-phosphate synthase activity
ADU62_RS02895	COG1960	acyl-CoA dehydrogenase activity
ADU62_RS02900	COG0583	DNA-binding transcription factor activity
ADU62_RS02915	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ADU62_RS02920	COG0259	pyridoxamine-phosphate oxidase activity
ADU62_RS02930	COG2814	Major facilitator Superfamily
ADU62_RS02935	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ADU62_RS02940	COG2188	Transcriptional regulator
ADU62_RS02945	COG0318	PFAM AMP-dependent synthetase and ligase
ADU62_RS02965	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ADU62_RS02975	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ADU62_RS02990	COG1215	transferase activity, transferring glycosyl groups
ADU62_RS03000	COG0601	transmembrane transport
ADU62_RS03015	COG0488	(ABC) transporter
ADU62_RS03035	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
ADU62_RS03040	COG2894	cell division
ADU62_RS03045	COG0850	regulation of cytokinetic process
ADU62_RS03050	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ADU62_RS03055	COG1271	oxidase subunit
ADU62_RS03090	COG2979	Protein of unknown function (DUF533)
ADU62_RS03110	COG1388	LysM domain
ADU62_RS03110	COG0741	lytic transglycosylase activity
ADU62_RS03115	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ADU62_RS03120	COG2226	methyltransferase
ADU62_RS03125	COG0328	RNA-DNA hybrid ribonuclease activity
ADU62_RS03175	COG2030	dehydratase
ADU62_RS03180	COG0183	Belongs to the thiolase family
ADU62_RS03225	COG1960	acyl-CoA dehydrogenase activity
ADU62_RS03240	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ADU62_RS03245	COG1028	Short-chain dehydrogenase reductase Sdr
ADU62_RS03260	COG2718	Belongs to the UPF0229 family
ADU62_RS03265	COG2719	SpoVR family
ADU62_RS03290	COG2188	Transcriptional regulator
ADU62_RS03305	COG0633	Ferredoxin
ADU62_RS03315	COG0829	nickel cation binding
ADU62_RS03320	COG0831	urea catabolic process
ADU62_RS03330	COG0832	Belongs to the urease beta subunit family
ADU62_RS03335	COG0804	urea catabolic process
ADU62_RS03345	COG0830	nickel cation binding
ADU62_RS03350	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ADU62_RS03370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ADU62_RS03375	COG0601	transmembrane transport
ADU62_RS03380	COG0747	negative chemotaxis
ADU62_RS03390	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ADU62_RS03395	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ADU62_RS03405	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ADU62_RS03415	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
ADU62_RS03420	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ADU62_RS03425	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ADU62_RS03440	COG0438	transferase activity, transferring glycosyl groups
ADU62_RS03455	COG0438	transferase activity, transferring glycosyl groups
ADU62_RS03460	COG0438	transferase activity, transferring glycosyl groups
ADU62_RS03465	COG0166	Belongs to the GPI family
ADU62_RS03480	COG0277	FAD linked oxidase domain protein
ADU62_RS03485	COG0745	RESPONSE REGULATOR receiver
ADU62_RS03490	COG0642	Histidine kinase
ADU62_RS03495	COG1368	sulfuric ester hydrolase activity
ADU62_RS03505	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
ADU62_RS03530	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ADU62_RS03540	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
ADU62_RS03545	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ADU62_RS03555	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ADU62_RS03560	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ADU62_RS03565	COG0193	aminoacyl-tRNA hydrolase activity
ADU62_RS03575	COG0012	GTP binding
ADU62_RS03580	COG0582	viral genome integration into host DNA
ADU62_RS03605	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ADU62_RS03670	COG0745	RESPONSE REGULATOR receiver
ADU62_RS03685	COG1309	transcriptional regulator
ADU62_RS03715	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ADU62_RS03725	COG0405	Gamma-glutamyltransferase
ADU62_RS03740	COG1280	lysine exporter protein (LysE YggA)
ADU62_RS03800	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
ADU62_RS03805	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ADU62_RS03815	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ADU62_RS03820	COG0513	Belongs to the DEAD box helicase family
ADU62_RS03830	COG0617	tRNA 3'-terminal CCA addition
ADU62_RS03845	COG0477	Major facilitator Superfamily
ADU62_RS03855	COG0583	DNA-binding transcription factor activity
ADU62_RS03870	COG1950	PFAM Membrane protein of
ADU62_RS03875	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ADU62_RS03890	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ADU62_RS03900	COG1560	Kdo2-lipid A biosynthetic process
ADU62_RS03905	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ADU62_RS03915	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ADU62_RS03925	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
ADU62_RS03935	COG0803	Belongs to the bacterial solute-binding protein 9 family
ADU62_RS03955	COG0735	belongs to the Fur family
ADU62_RS03960	COG0523	cobalamin synthesis protein
ADU62_RS03970	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ADU62_RS03975	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ADU62_RS03985	COG2096	Adenosyltransferase
ADU62_RS04000	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ADU62_RS04005	COG2084	Dehydrogenase
ADU62_RS04055	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ADU62_RS04060	COG0129	dihydroxy-acid dehydratase activity
ADU62_RS04065	COG4654	Cytochrome c, class I
ADU62_RS04070	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ADU62_RS04120	COG1473	amidohydrolase
ADU62_RS04125	COG0418	dihydroorotase activity
ADU62_RS04130	COG0488	(ABC) transporter
ADU62_RS04140	COG2001	Belongs to the MraZ family
ADU62_RS04145	COG0275	rRNA processing
ADU62_RS04150	COG3116	cell division
ADU62_RS04160	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ADU62_RS04165	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ADU62_RS04170	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ADU62_RS04180	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ADU62_RS04185	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ADU62_RS04190	COG1181	Belongs to the D-alanine--D-alanine ligase family
ADU62_RS04195	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ADU62_RS04205	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ADU62_RS04210	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ADU62_RS04220	COG0739	heme binding
ADU62_RS04225	COG0653	protein targeting
ADU62_RS04245	COG1028	Short-chain dehydrogenase reductase Sdr
ADU62_RS04250	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ADU62_RS04255	COG1522	sequence-specific DNA binding
ADU62_RS04280	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ADU62_RS04290	COG0557	exoribonuclease II activity
ADU62_RS04295	COG3150	esterase
ADU62_RS04300	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ADU62_RS04305	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ADU62_RS04310	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ADU62_RS04315	COG0511	ligase activity, forming carbon-carbon bonds
ADU62_RS04320	COG0439	Biotin carboxylase
ADU62_RS04325	COG2264	protein methyltransferase activity
ADU62_RS04335	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ADU62_RS04360	COG1696	Membrane protein involved in D-alanine export
ADU62_RS04365	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ADU62_RS04400	COG1522	sequence-specific DNA binding
ADU62_RS04415	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ADU62_RS04420	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ADU62_RS04420	COG1042	CoA-binding domain protein
ADU62_RS04420	COG0045	succinate-CoA ligase (ADP-forming) activity
ADU62_RS04435	COG1802	Transcriptional regulator
ADU62_RS04440	COG3069	C4-dicarboxylate transmembrane transporter activity
ADU62_RS04445	COG0513	Belongs to the DEAD box helicase family
ADU62_RS04450	COG0346	lactoylglutathione lyase activity
ADU62_RS04455	COG1335	isochorismatase
ADU62_RS04460	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ADU62_RS04465	COG1116	anion transmembrane transporter activity
ADU62_RS04480	COG3028	Belongs to the UPF0307 family
ADU62_RS04485	COG0312	modulator of DNA gyrase
ADU62_RS04490	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ADU62_RS04495	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ADU62_RS04500	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ADU62_RS04505	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ADU62_RS04515	COG0316	Belongs to the HesB IscA family
ADU62_RS04520	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
ADU62_RS04535	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ADU62_RS04545	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ADU62_RS04550	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ADU62_RS04565	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ADU62_RS04565	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ADU62_RS04595	COG0583	DNA-binding transcription factor activity
ADU62_RS04600	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ADU62_RS04635	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
ADU62_RS04645	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ADU62_RS04650	COG1845	cytochrome c oxidase, subunit III
ADU62_RS04655	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ADU62_RS04660	COG0640	Transcriptional regulator
ADU62_RS04680	COG3220	belongs to the UPF0276 family
ADU62_RS04725	COG1666	GTP binding
ADU62_RS04760	COG0312	modulator of DNA gyrase
ADU62_RS04765	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ADU62_RS04770	COG3210	domain, Protein
ADU62_RS04770	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
ADU62_RS04770	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
ADU62_RS04770	COG3210	domain, Protein
ADU62_RS04770	COG3064	Membrane
ADU62_RS04770	COG3064	Membrane
ADU62_RS04775	COG0277	FAD linked oxidase domain protein
ADU62_RS04780	COG0277	FAD linked oxidase domain protein
ADU62_RS04785	COG0277	FAD linked oxidase domain protein
ADU62_RS04790	COG0247	lactate metabolic process
ADU62_RS04795	COG2819	hydrolase of the alpha beta superfamily
ADU62_RS04820	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ADU62_RS04840	COG0583	DNA-binding transcription factor activity
ADU62_RS04845	COG0482	sulfurtransferase activity
ADU62_RS04850	COG0730	response to heat
ADU62_RS04855	COG0625	glutathione transferase activity
ADU62_RS04860	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ADU62_RS04865	COG3909	cytochrome
ADU62_RS04905	COG0154	amidase activity
ADU62_RS04910	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ADU62_RS04915	COG1024	Enoyl-CoA hydratase
ADU62_RS04930	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ADU62_RS04945	COG1028	Short-chain dehydrogenase reductase Sdr
ADU62_RS04950	COG1414	Transcriptional regulator
ADU62_RS04960	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ADU62_RS04965	COG0251	oxidation-reduction process
ADU62_RS04970	COG0559	Belongs to the binding-protein-dependent transport system permease family
ADU62_RS04990	COG1902	pentaerythritol trinitrate reductase activity
ADU62_RS05005	COG0583	DNA-binding transcription factor activity
ADU62_RS05015	COG0590	tRNA wobble adenosine to inosine editing
ADU62_RS05020	COG2807	transmembrane transport
ADU62_RS05040	COG0154	amidase activity
ADU62_RS05045	COG0307	riboflavin synthase, alpha
ADU62_RS05050	COG3181	Tripartite tricarboxylate transporter family receptor
ADU62_RS05055	COG1522	sequence-specific DNA binding
ADU62_RS05065	COG0318	PFAM AMP-dependent synthetase and ligase
ADU62_RS05075	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ADU62_RS05095	COG1063	alcohol dehydrogenase
ADU62_RS05120	COG1418	mRNA catabolic process
ADU62_RS05125	COG1448	Aminotransferase
ADU62_RS05130	COG0583	DNA-binding transcription factor activity
ADU62_RS05140	COG0477	Major facilitator Superfamily
ADU62_RS05145	COG1028	Short-chain dehydrogenase reductase Sdr
ADU62_RS05160	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ADU62_RS05165	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ADU62_RS05170	COG0583	DNA-binding transcription factor activity
ADU62_RS05230	COG1028	Short-chain dehydrogenase reductase Sdr
ADU62_RS05235	COG1309	transcriptional regulator
ADU62_RS05245	COG2982	Protein involved in outer membrane biogenesis
ADU62_RS05250	COG2818	Glycosylase
ADU62_RS05270	COG1653	transport
ADU62_RS05280	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ADU62_RS05285	COG3842	ATPase activity
ADU62_RS05290	COG0395	ABC-type sugar transport system, permease component
ADU62_RS05295	COG1175	transmembrane transport
ADU62_RS05315	COG3181	Tripartite tricarboxylate transporter family receptor
ADU62_RS05320	COG2186	Transcriptional regulator
ADU62_RS05350	COG1454	alcohol dehydrogenase
ADU62_RS05370	COG2011	ABC-type metal ion transport system permease component
ADU62_RS05375	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ADU62_RS05380	COG1501	Belongs to the glycosyl hydrolase 31 family
ADU62_RS05405	COG0318	PFAM AMP-dependent synthetase and ligase
ADU62_RS05410	COG1473	amidohydrolase
ADU62_RS05420	COG2855	membrane
ADU62_RS05430	COG2239	Acts as a magnesium transporter
ADU62_RS05450	COG3181	Tripartite tricarboxylate transporter family receptor
ADU62_RS05460	COG1722	exodeoxyribonuclease VII activity
ADU62_RS05465	COG0142	geranyltranstransferase activity
ADU62_RS05470	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ADU62_RS05475	COG1469	GTP cyclohydrolase I activity
ADU62_RS05480	COG0360	Binds together with S18 to 16S ribosomal RNA
ADU62_RS05485	COG2965	DNA replication, synthesis of RNA primer
ADU62_RS05490	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ADU62_RS05495	COG0359	binds to the 23S rRNA
ADU62_RS05505	COG0305	Participates in initiation and elongation during chromosome replication
ADU62_RS05515	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ADU62_RS05520	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ADU62_RS05525	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ADU62_RS05530	COG3737	Protein of unknown function (DUF498/DUF598)
ADU62_RS05535	COG0436	Aminotransferase
ADU62_RS05560	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ADU62_RS05590	COG0268	Binds directly to 16S ribosomal RNA
ADU62_RS05600	COG0728	peptidoglycan biosynthetic process
ADU62_RS05610	COG0563	adenylate kinase activity
ADU62_RS05615	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ADU62_RS05620	COG2835	tetraacyldisaccharide 4'-kinase activity
ADU62_RS05625	COG1663	tetraacyldisaccharide 4'-kinase activity
ADU62_RS05630	COG0848	biopolymer transport protein
ADU62_RS05635	COG0811	peptide transport
ADU62_RS05645	COG1570	exodeoxyribonuclease VII activity
ADU62_RS05650	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ADU62_RS05655	COG0038	chloride channel
ADU62_RS05660	COG0183	Belongs to the thiolase family
ADU62_RS05670	COG1278	Cold shock
ADU62_RS05675	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ADU62_RS05685	COG4953	penicillin-binding protein 1C
ADU62_RS05690	COG0542	response to heat
ADU62_RS05695	COG2995	paraquat-inducible protein a
ADU62_RS05700	COG3008	intermembrane lipid transfer
ADU62_RS05700	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ADU62_RS05710	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ADU62_RS05710	COG0506	proline dehydrogenase activity
ADU62_RS05710	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ADU62_RS05745	COG2271	Major facilitator Superfamily
ADU62_RS05750	COG1309	transcriptional regulator
ADU62_RS05760	COG3468	outer membrane autotransporter barrel domain protein
ADU62_RS05790	COG0477	Major facilitator Superfamily
ADU62_RS05800	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ADU62_RS05805	COG1845	cytochrome c oxidase, subunit III
ADU62_RS05810	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ADU62_RS05820	COG1028	Short-chain dehydrogenase reductase Sdr
ADU62_RS05835	COG0789	Transcriptional regulator
ADU62_RS05860	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ADU62_RS05865	COG0697	spore germination
ADU62_RS05875	COG0678	peroxiredoxin activity
ADU62_RS05885	COG0412	Dienelactone hydrolase
ADU62_RS05895	COG0315	cyclic pyranopterin monophosphate synthase activity
ADU62_RS05910	COG0521	Mo-molybdopterin cofactor biosynthetic process
ADU62_RS05915	COG0303	'Molybdopterin
ADU62_RS05920	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ADU62_RS05940	COG0165	Argininosuccinate lyase
ADU62_RS05945	COG0668	transmembrane transport
ADU62_RS05990	COG0747	negative chemotaxis
ADU62_RS05995	COG0601	transmembrane transport
ADU62_RS06000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ADU62_RS06005	COG1162	GTPase activity
ADU62_RS06010	COG0501	Belongs to the peptidase M48B family
ADU62_RS06015	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ADU62_RS06025	COG3327	negative regulation of DNA-templated transcription, initiation
ADU62_RS06030	COG3396	Phenylacetate-CoA oxygenase
ADU62_RS06035	COG3460	Phenylacetate-CoA oxygenase
ADU62_RS06040	COG3396	Phenylacetate-CoA oxygenase
ADU62_RS06045	COG2151	metal-sulfur cluster biosynthetic enzyme
ADU62_RS06050	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ADU62_RS06060	COG1012	belongs to the aldehyde dehydrogenase family
ADU62_RS06065	COG1024	Enoyl-CoA hydratase
ADU62_RS06070	COG2050	protein possibly involved in aromatic compounds catabolism
ADU62_RS06080	COG3539	Fimbrial protein
ADU62_RS06100	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ADU62_RS06105	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ADU62_RS06105	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ADU62_RS06110	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ADU62_RS06115	COG0047	phosphoribosylformylglycinamidine synthase activity
ADU62_RS06115	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ADU62_RS06120	COG3064	Membrane
ADU62_RS06120	COG3210	domain, Protein
ADU62_RS06120	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
ADU62_RS06145	COG0235	Class ii aldolase
ADU62_RS06150	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ADU62_RS06155	COG0720	synthase
ADU62_RS06160	COG0602	queuosine metabolic process
ADU62_RS06185	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ADU62_RS06220	COG3181	Tripartite tricarboxylate transporter family receptor
ADU62_RS06250	COG3842	ATPase activity
ADU62_RS06260	COG0395	ABC-type sugar transport system, permease component
ADU62_RS06290	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ADU62_RS06295	COG0420	3'-5' exonuclease activity
ADU62_RS06340	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ADU62_RS06340	COG0519	Catalyzes the synthesis of GMP from XMP
ADU62_RS06355	COG3550	peptidyl-serine autophosphorylation
ADU62_RS06365	COG0477	Major facilitator Superfamily
ADU62_RS06380	COG1228	amidohydrolase
ADU62_RS06390	COG1116	anion transmembrane transporter activity
ADU62_RS06395	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ADU62_RS06435	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ADU62_RS06450	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ADU62_RS06480	COG2814	Major facilitator Superfamily
ADU62_RS06495	COG1280	lysine exporter protein (LysE YggA)
ADU62_RS06510	COG0747	negative chemotaxis
ADU62_RS06515	COG0601	transmembrane transport
ADU62_RS06520	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ADU62_RS06525	COG4172	Belongs to the ABC transporter superfamily
ADU62_RS06530	COG1609	Transcriptional regulator
ADU62_RS06560	COG0586	Pfam SNARE associated Golgi protein
ADU62_RS06575	COG0500	methyltransferase
ADU62_RS06590	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ADU62_RS06600	COG0756	dUTP diphosphatase activity
ADU62_RS06615	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ADU62_RS06620	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ADU62_RS06625	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ADU62_RS06630	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ADU62_RS06630	COG0072	phenylalanine-tRNA ligase activity
ADU62_RS06635	COG0776	regulation of translation
ADU62_RS06705	COG0540	Belongs to the ATCase OTCase family
ADU62_RS06710	COG2974	May be involved in recombination
ADU62_RS06720	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ADU62_RS06725	COG0583	DNA-binding transcription factor activity
ADU62_RS06745	COG1028	Short-chain dehydrogenase reductase Sdr
ADU62_RS06760	COG3842	ATPase activity
ADU62_RS06765	COG1250	3-hydroxyacyl-CoA dehydrogenase
ADU62_RS06765	COG1024	Enoyl-CoA hydratase
ADU62_RS06785	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ADU62_RS06790	COG2137	regulation of response to DNA damage stimulus
ADU62_RS06800	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ADU62_RS06810	COG0045	succinate-CoA ligase (ADP-forming) activity
ADU62_RS06815	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ADU62_RS06820	COG0861	Integral membrane protein TerC family
ADU62_RS06825	COG0861	Integral membrane protein TerC family
ADU62_RS06830	COG0181	hydroxymethylbilane synthase activity
ADU62_RS06890	COG4964	Belongs to the GSP D family
ADU62_RS06920	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ADU62_RS06930	COG0583	DNA-binding transcription factor activity
ADU62_RS06940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ADU62_RS06945	COG4311	Sarcosine oxidase, delta subunit
ADU62_RS06950	COG0446	pyridine nucleotide-disulphide oxidoreductase
ADU62_RS06950	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ADU62_RS06985	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ADU62_RS06990	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ADU62_RS06995	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ADU62_RS07000	COG0735	belongs to the Fur family
ADU62_RS07005	COG0497	DNA recombination
ADU62_RS07010	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ADU62_RS07015	COG1420	regulation of RNA biosynthetic process
ADU62_RS07020	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ADU62_RS07030	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ADU62_RS07040	COG0443	Heat shock 70 kDa protein
ADU62_RS07050	COG0612	Peptidase, M16
ADU62_RS07070	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ADU62_RS07115	COG0745	RESPONSE REGULATOR receiver
ADU62_RS07125	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
ADU62_RS07130	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
ADU62_RS07135	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ADU62_RS07150	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ADU62_RS07170	COG1193	negative regulation of DNA recombination
ADU62_RS07175	COG0492	ferredoxin-NADP+ reductase activity
ADU62_RS07180	COG1674	ftsk spoiiie
ADU62_RS07185	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ADU62_RS07190	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ADU62_RS07195	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ADU62_RS07220	COG3706	GGDEF domain
ADU62_RS07240	COG2814	Major facilitator Superfamily
ADU62_RS07270	COG3486	L-lysine 6-monooxygenase (NADPH) activity
ADU62_RS07285	COG1028	Short-chain dehydrogenase reductase Sdr
ADU62_RS07295	COG3022	response to hydroperoxide
ADU62_RS07305	COG1289	transmembrane transporter activity
ADU62_RS07325	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ADU62_RS07335	COG2197	response regulator
ADU62_RS07340	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ADU62_RS07345	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ADU62_RS07350	COG0189	ligase activity
ADU62_RS07360	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ADU62_RS07365	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ADU62_RS07375	COG1764	response to oxidative stress
ADU62_RS07380	COG2423	ornithine cyclodeaminase activity
ADU62_RS07390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ADU62_RS07395	COG0765	amino acid transport
ADU62_RS07400	COG0765	amino acid transport
ADU62_RS07405	COG1126	abc transporter atp-binding protein
ADU62_RS07460	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ADU62_RS07470	COG2944	sequence-specific DNA binding
ADU62_RS07480	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ADU62_RS07485	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ADU62_RS07490	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ADU62_RS07495	COG0009	L-threonylcarbamoyladenylate synthase
ADU62_RS07500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ADU62_RS07505	COG1414	Transcriptional regulator
ADU62_RS07520	COG0765	amino acid transport
ADU62_RS07525	COG1126	abc transporter atp-binding protein
ADU62_RS07530	COG0028	Belongs to the TPP enzyme family
ADU62_RS07545	COG0028	Belongs to the TPP enzyme family
ADU62_RS07550	COG0583	DNA-binding transcription factor activity
ADU62_RS07555	COG4974	Belongs to the 'phage' integrase family
ADU62_RS07560	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ADU62_RS07565	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
ADU62_RS07580	COG1686	Belongs to the peptidase S11 family
ADU62_RS07590	COG2814	Major facilitator Superfamily
ADU62_RS07600	COG1074	ATP-dependent DNA helicase activity
ADU62_RS07615	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ADU62_RS07620	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ADU62_RS07625	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ADU62_RS07645	COG2321	neutral zinc metallopeptidase
ADU62_RS07650	COG0009	L-threonylcarbamoyladenylate synthase
ADU62_RS07695	COG3360	Dodecin
ADU62_RS07700	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ADU62_RS07705	COG2850	peptidyl-arginine hydroxylation
ADU62_RS07710	COG3539	Fimbrial protein
ADU62_RS07715	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
ADU62_RS07720	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ADU62_RS07740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ADU62_RS07745	COG0765	amino acid transport
ADU62_RS07750	COG1126	abc transporter atp-binding protein
ADU62_RS07755	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ADU62_RS07760	COG1758	RNA polymerase activity
ADU62_RS07765	COG0194	GDP metabolic process
ADU62_RS07770	COG3258	Cytochrome c
ADU62_RS07775	COG2863	cytochrome
ADU62_RS07780	COG1028	Short-chain dehydrogenase reductase Sdr
ADU62_RS07785	COG0791	NLP P60 protein
ADU62_RS07790	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ADU62_RS07810	COG1561	YicC-like family, N-terminal region
ADU62_RS07815	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ADU62_RS07830	COG0840	transmembrane signaling receptor activity
ADU62_RS07835	COG2200	EAL domain
ADU62_RS07835	COG2199	diguanylate cyclase activity
ADU62_RS07840	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ADU62_RS07850	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ADU62_RS07855	COG0174	glutamine synthetase
ADU62_RS07865	COG2204	response regulator
ADU62_RS07870	COG0583	DNA-binding transcription factor activity
ADU62_RS07875	COG1741	Belongs to the pirin family
ADU62_RS07880	COG1741	Belongs to the pirin family
ADU62_RS07890	COG3842	ATPase activity
ADU62_RS07895	COG1178	ABC-type Fe3 transport system permease component
ADU62_RS07900	COG1840	ABC-type Fe3 transport system, periplasmic component
ADU62_RS07910	COG0583	DNA-binding transcription factor activity
ADU62_RS07920	COG0656	L-ascorbic acid biosynthetic process
ADU62_RS07935	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ADU62_RS07940	COG0583	DNA-binding transcription factor activity
ADU62_RS07955	COG0783	Belongs to the Dps family
ADU62_RS07975	COG0463	Glycosyl transferase, family 2
ADU62_RS07995	COG0438	transferase activity, transferring glycosyl groups
ADU62_RS08010	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ADU62_RS08035	COG0300	oxidoreductase activity
ADU62_RS08080	COG0861	Integral membrane protein TerC family
ADU62_RS08085	COG1028	Short-chain dehydrogenase reductase Sdr
ADU62_RS08105	COG0714	Associated with various cellular activities
ADU62_RS08140	COG3119	arylsulfatase activity
ADU62_RS08165	COG2197	response regulator
ADU62_RS08175	COG2944	sequence-specific DNA binding
ADU62_RS08180	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
ADU62_RS08185	COG0625	glutathione transferase activity
ADU62_RS08215	COG0179	Fumarylacetoacetate (FAA) hydrolase
ADU62_RS08220	COG1028	Short-chain dehydrogenase reductase Sdr
ADU62_RS08265	COG0431	NADPH-dependent FMN reductase
ADU62_RS08295	COG1028	Short-chain dehydrogenase reductase Sdr
ADU62_RS08300	COG0583	DNA-binding transcription factor activity
ADU62_RS08315	COG3181	Tripartite tricarboxylate transporter family receptor
ADU62_RS08320	COG2111	Na H antiporter
ADU62_RS08320	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ADU62_RS08325	COG1006	Multisubunit Na H antiporter MnhC subunit
ADU62_RS08330	COG0651	ATP synthesis coupled electron transport
ADU62_RS08335	COG1863	multisubunit Na H antiporter MnhE subunit
ADU62_RS08340	COG2212	antiporter activity
ADU62_RS08365	COG0590	tRNA wobble adenosine to inosine editing
ADU62_RS08370	COG1619	proteins homologs of microcin C7 resistance protein MccF
ADU62_RS08375	COG1024	Enoyl-CoA hydratase
ADU62_RS08390	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ADU62_RS08395	COG0488	(ABC) transporter
ADU62_RS08430	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ADU62_RS08430	COG1017	nitric oxide dioxygenase activity
ADU62_RS08435	COG1959	2 iron, 2 sulfur cluster binding
ADU62_RS08440	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ADU62_RS08470	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ADU62_RS08475	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ADU62_RS08480	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ADU62_RS08485	COG0084	hydrolase, TatD family'
ADU62_RS08500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ADU62_RS08510	COG1126	abc transporter atp-binding protein
ADU62_RS08515	COG0010	Belongs to the arginase family
ADU62_RS08520	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ADU62_RS08525	COG1012	belongs to the aldehyde dehydrogenase family
ADU62_RS08535	COG0028	Belongs to the TPP enzyme family
ADU62_RS08545	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ADU62_RS08545	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ADU62_RS08555	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ADU62_RS08570	COG3189	MarR family transcriptional regulator
ADU62_RS08575	COG2010	Cytochrome c
ADU62_RS08600	COG4336	lyase activity
ADU62_RS08610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ADU62_RS08610	COG2205	protein histidine kinase activity
ADU62_RS08615	COG2197	response regulator
ADU62_RS08620	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
ADU62_RS08620	COG3210	domain, Protein
ADU62_RS08620	COG3064	Membrane
ADU62_RS08630	COG3121	Chaperone
ADU62_RS08635	COG3188	usher protein
ADU62_RS08640	COG3539	Fimbrial protein
ADU62_RS08645	COG2831	hemolysin activation secretion protein
ADU62_RS08660	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ADU62_RS08685	COG0583	DNA-binding transcription factor activity
ADU62_RS08710	COG0668	transmembrane transport
ADU62_RS08730	COG0483	inositol monophosphate 1-phosphatase activity
ADU62_RS08735	COG1253	flavin adenine dinucleotide binding
ADU62_RS08740	COG1968	undecaprenyl-diphosphatase activity
ADU62_RS08745	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ADU62_RS08760	COG0215	cysteine-tRNA ligase activity
ADU62_RS08770	COG0825	malonyl-CoA metabolic process
ADU62_RS08780	COG0037	tRNA processing
ADU62_RS08785	COG0527	aspartate kinase activity
ADU62_RS08810	COG1250	3-hydroxyacyl-CoA dehydrogenase
ADU62_RS08815	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ADU62_RS08815	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ADU62_RS08830	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ADU62_RS08835	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
ADU62_RS08840	COG1028	Short-chain dehydrogenase reductase Sdr
ADU62_RS08850	COG0583	DNA-binding transcription factor activity
ADU62_RS08880	COG3842	ATPase activity
ADU62_RS08890	COG0446	pyridine nucleotide-disulphide oxidoreductase
ADU62_RS08890	COG1902	pentaerythritol trinitrate reductase activity
ADU62_RS08895	COG1414	Transcriptional regulator
ADU62_RS08900	COG1832	CoA-binding protein
ADU62_RS08910	COG0251	oxidation-reduction process
ADU62_RS08935	COG1902	pentaerythritol trinitrate reductase activity
ADU62_RS08945	COG1215	transferase activity, transferring glycosyl groups
ADU62_RS08950	COG0726	polysaccharide deacetylase
ADU62_RS08950	COG1649	PFAM Uncharacterised BCR, COG1649
ADU62_RS08970	COG1846	Transcriptional regulator
ADU62_RS08975	COG2197	response regulator
ADU62_RS08990	COG0166	Belongs to the GPI family
ADU62_RS08995	COG1045	serine acetyltransferase
ADU62_RS09005	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ADU62_RS09010	COG0483	inositol monophosphate 1-phosphatase activity
ADU62_RS09015	COG1012	belongs to the aldehyde dehydrogenase family
ADU62_RS09020	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ADU62_RS09035	COG0210	DNA helicase
ADU62_RS09040	COG0598	Magnesium transport protein CorA
ADU62_RS09050	COG0747	negative chemotaxis
ADU62_RS09055	COG0601	transmembrane transport
ADU62_RS09060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ADU62_RS09065	COG4172	Belongs to the ABC transporter superfamily
ADU62_RS09070	COG1846	Transcriptional regulator
ADU62_RS09120	COG4964	Belongs to the GSP D family
ADU62_RS09160	COG2204	response regulator
ADU62_RS09175	COG1595	DNA-templated transcription, initiation
ADU62_RS09185	COG3474	cytochrome
ADU62_RS09190	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ADU62_RS09205	COG3384	dioxygenase
ADU62_RS09210	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ADU62_RS09235	COG2885	chlorophyll binding
ADU62_RS09270	COG0697	spore germination
ADU62_RS09275	COG0730	response to heat
ADU62_RS09295	COG0583	DNA-binding transcription factor activity
ADU62_RS09300	COG0427	acetyl-CoA hydrolase
ADU62_RS09355	COG1250	3-hydroxyacyl-CoA dehydrogenase
ADU62_RS09360	COG0154	amidase activity
ADU62_RS09370	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ADU62_RS09385	COG0495	leucyl-tRNA aminoacylation
ADU62_RS09390	COG2814	Major facilitator Superfamily
ADU62_RS09420	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ADU62_RS09425	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ADU62_RS09430	COG2814	Major facilitator Superfamily
ADU62_RS09435	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ADU62_RS09450	COG4176	ABC-type proline glycine betaine transport system permease component
ADU62_RS09460	COG1942	4-Oxalocrotonate Tautomerase
ADU62_RS09465	COG0183	Belongs to the thiolase family
ADU62_RS09475	COG1802	Transcriptional regulator
ADU62_RS09485	COG1024	Enoyl-CoA hydratase
ADU62_RS09490	COG0318	PFAM AMP-dependent synthetase and ligase
ADU62_RS09495	COG0318	PFAM AMP-dependent synthetase and ligase
ADU62_RS09505	COG2032	superoxide dismutase activity
ADU62_RS09520	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
ADU62_RS09545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ADU62_RS09550	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ADU62_RS09560	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ADU62_RS09565	COG0736	holo-[acyl-carrier-protein] synthase activity
ADU62_RS09570	COG1472	Belongs to the glycosyl hydrolase 3 family
ADU62_RS09575	COG0322	excinuclease ABC activity
ADU62_RS09580	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ADU62_RS09595	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ADU62_RS09595	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ADU62_RS09600	COG2224	Isocitrate lyase
ADU62_RS09620	COG0559	Belongs to the binding-protein-dependent transport system permease family
ADU62_RS09630	COG4638	Rieske (2fe-2S)
ADU62_RS09640	COG1024	Enoyl-CoA hydratase
ADU62_RS09650	COG0633	Ferredoxin
ADU62_RS09655	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ADU62_RS09670	COG0183	Belongs to the thiolase family
ADU62_RS09715	COG2346	COG2346, Truncated hemoglobins
ADU62_RS09845	COG2207	Transcriptional regulator
ADU62_RS09890	COG1132	(ABC) transporter
ADU62_RS09915	COG0659	secondary active sulfate transmembrane transporter activity
ADU62_RS09945	COG2169	Transcriptional regulator
ADU62_RS09950	COG5507	3-demethylubiquinone-9 3-methyltransferase
ADU62_RS09955	COG0384	phenazine biosynthesis protein PhzF
ADU62_RS09960	COG0583	DNA-binding transcription factor activity
ADU62_RS09965	COG2733	membrane
ADU62_RS09980	COG1012	belongs to the aldehyde dehydrogenase family
ADU62_RS09985	COG3284	Transcriptional regulator
ADU62_RS10005	COG1380	Effector of murein hydrolase LrgA
ADU62_RS10010	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ADU62_RS10010	COG4106	trans-aconitate 2-methyltransferase activity
ADU62_RS10020	COG0156	8-amino-7-oxononanoate synthase activity
ADU62_RS10090	COG1131	(ABC) transporter
ADU62_RS10095	COG0842	Transport permease protein
ADU62_RS10100	COG0628	permease
ADU62_RS10130	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ADU62_RS10140	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ADU62_RS10145	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ADU62_RS10150	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ADU62_RS10155	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ADU62_RS10160	COG0330	HflC and HflK could
ADU62_RS10165	COG0330	HflC and HflK could
ADU62_RS10170	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ADU62_RS10175	COG1923	regulation of RNA biosynthetic process
ADU62_RS10180	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ADU62_RS10185	COG1160	GTP binding
ADU62_RS10190	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ADU62_RS10195	COG2976	Protein conserved in bacteria
ADU62_RS10200	COG0124	histidyl-tRNA synthetase
ADU62_RS10205	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ADU62_RS10215	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ADU62_RS10220	COG0105	UTP biosynthetic process
ADU62_RS10225	COG0525	valine-tRNA ligase activity
ADU62_RS10240	COG0642	Histidine kinase
ADU62_RS10260	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ADU62_RS10265	COG0336	Belongs to the RNA methyltransferase TrmD family
ADU62_RS10270	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ADU62_RS10275	COG0228	four-way junction DNA binding
ADU62_RS10285	COG0425	Belongs to the sulfur carrier protein TusA family
ADU62_RS10290	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ADU62_RS10335	COG0154	amidase activity
ADU62_RS10340	COG4172	Belongs to the ABC transporter superfamily
ADU62_RS10345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ADU62_RS10350	COG0601	transmembrane transport
ADU62_RS10355	COG0747	negative chemotaxis
ADU62_RS10385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ADU62_RS10395	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ADU62_RS10410	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ADU62_RS10415	COG3395	kinase activity
ADU62_RS10430	COG1024	Enoyl-CoA hydratase
ADU62_RS10450	COG0633	Ferredoxin
ADU62_RS10455	COG0443	Heat shock 70 kDa protein
ADU62_RS10460	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ADU62_RS10465	COG0316	Belongs to the HesB IscA family
ADU62_RS10470	COG0822	iron-sulfur transferase activity
ADU62_RS10475	COG1104	cysteine desulfurase activity
ADU62_RS10485	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ADU62_RS10490	COG0556	nucleotide-excision repair
ADU62_RS10500	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ADU62_RS10505	COG3468	outer membrane autotransporter barrel domain protein
ADU62_RS10535	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ADU62_RS10550	COG1960	acyl-CoA dehydrogenase activity
ADU62_RS10555	COG1028	Short-chain dehydrogenase reductase Sdr
ADU62_RS10560	COG0183	Belongs to the thiolase family
ADU62_RS10570	COG1024	Enoyl-CoA hydratase
ADU62_RS10585	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ADU62_RS10590	COG0583	DNA-binding transcription factor activity
ADU62_RS10595	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ADU62_RS10600	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ADU62_RS10605	COG0740	serine-type endopeptidase activity
ADU62_RS10610	COG0544	peptidyl-prolyl cis-trans isomerase activity
ADU62_RS10630	COG1278	Cold shock
ADU62_RS10665	COG2171	N-acyltransferase activity
ADU62_RS10670	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ADU62_RS10675	COG2890	protein-(glutamine-N5) methyltransferase activity
ADU62_RS10680	COG0488	(ABC) transporter
ADU62_RS10685	COG4771	TonB-dependent receptor
ADU62_RS10690	COG0210	DNA helicase
ADU62_RS10710	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ADU62_RS10715	COG0196	riboflavin kinase activity
ADU62_RS10720	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ADU62_RS10725	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ADU62_RS10730	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ADU62_RS10740	COG1522	sequence-specific DNA binding
ADU62_RS10760	COG2951	lytic endotransglycosylase activity
ADU62_RS10765	COG2833	Protein of unknown function (DUF455)
ADU62_RS10785	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ADU62_RS10785	COG0189	ligase activity
ADU62_RS10790	COG1181	Belongs to the D-alanine--D-alanine ligase family
ADU62_RS10790	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ADU62_RS10795	COG3237	CsbD-like
ADU62_RS10805	COG2823	Periplasmic or secreted lipoprotein
ADU62_RS10820	COG4181	ATPase activity
ADU62_RS10830	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ADU62_RS10835	COG0584	glycerophosphoryl diester phosphodiesterase
ADU62_RS10840	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ADU62_RS10850	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ADU62_RS10850	COG0678	peroxiredoxin activity
ADU62_RS10860	COG0789	Transcriptional regulator
ADU62_RS10865	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ADU62_RS10895	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ADU62_RS10900	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ADU62_RS10910	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ADU62_RS10915	COG2252	PERMEase
ADU62_RS10925	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ADU62_RS10955	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ADU62_RS10960	COG2358	TRAP transporter, solute receptor (TAXI family
ADU62_RS10990	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ADU62_RS10995	COG1366	Belongs to the anti-sigma-factor antagonist family
ADU62_RS11000	COG2172	sigma factor antagonist activity
ADU62_RS11005	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ADU62_RS11015	COG2770	Histidine kinase
ADU62_RS11015	COG2208	phosphoserine phosphatase activity
ADU62_RS11035	COG1595	DNA-templated transcription, initiation
ADU62_RS11050	COG4792	protein secretion
ADU62_RS11055	COG4791	protein targeting
ADU62_RS11060	COG4794	Type iii secretion
ADU62_RS11065	COG4790	Type iii secretion
ADU62_RS11100	COG4669	(LipO)protein
ADU62_RS11165	COG4789	Type iii secretion
ADU62_RS11195	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ADU62_RS11200	COG0840	transmembrane signaling receptor activity
ADU62_RS11205	COG2233	PERMEase
ADU62_RS11225	COG0492	ferredoxin-NADP+ reductase activity
ADU62_RS11230	COG1840	ABC-type Fe3 transport system, periplasmic component
ADU62_RS11235	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ADU62_RS11240	COG1178	ABC-type Fe3 transport system permease component
ADU62_RS11245	COG3842	ATPase activity
ADU62_RS11250	COG0583	DNA-binding transcription factor activity
ADU62_RS11270	COG0501	Belongs to the peptidase M48B family
ADU62_RS11280	COG0697	spore germination
ADU62_RS11290	COG1846	Transcriptional regulator
ADU62_RS11300	COG1566	PFAM secretion protein HlyD family protein
ADU62_RS11305	COG2814	Major facilitator Superfamily
ADU62_RS11310	COG0473	3-isopropylmalate dehydrogenase activity
ADU62_RS11320	COG0747	negative chemotaxis
ADU62_RS11330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ADU62_RS11345	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ADU62_RS11370	COG1012	belongs to the aldehyde dehydrogenase family
ADU62_RS11380	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ADU62_RS11385	COG1115	amino acid carrier protein
ADU62_RS11390	COG0433	COG0433 Predicted ATPase
ADU62_RS11395	COG0217	transcriptional regulatory protein
ADU62_RS11400	COG0151	Belongs to the GarS family
ADU62_RS11405	COG0408	coproporphyrinogen oxidase activity
ADU62_RS11410	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ADU62_RS11415	COG0799	negative regulation of ribosome biogenesis
ADU62_RS11420	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ADU62_RS11425	COG0424	maF-like protein
ADU62_RS11430	COG3468	outer membrane autotransporter barrel domain protein
ADU62_RS11470	COG1530	ribonuclease E activity
ADU62_RS11475	COG0077	Prephenate dehydratase
ADU62_RS11490	COG1132	(ABC) transporter
ADU62_RS11495	COG0859	PFAM glycosyl transferase family 9
ADU62_RS11520	COG2194	sulfuric ester hydrolase activity
ADU62_RS11525	COG0438	transferase activity, transferring glycosyl groups
ADU62_RS11530	COG0463	Glycosyl transferase, family 2
ADU62_RS11535	COG0726	polysaccharide deacetylase
ADU62_RS11540	COG0438	transferase activity, transferring glycosyl groups
ADU62_RS11555	COG1643	Atp-dependent helicase
ADU62_RS11560	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ADU62_RS11560	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ADU62_RS11565	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
ADU62_RS11575	COG0704	Plays a role in the regulation of phosphate uptake
ADU62_RS11580	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ADU62_RS11585	COG1960	acyl-CoA dehydrogenase activity
ADU62_RS11610	COG1177	transmembrane transport
ADU62_RS11615	COG1176	ABC-type spermidine putrescine transport system, permease component I
ADU62_RS11620	COG3842	ATPase activity
ADU62_RS11625	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ADU62_RS11640	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
ADU62_RS11645	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ADU62_RS11655	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ADU62_RS11655	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ADU62_RS11675	COG0372	Belongs to the citrate synthase family
ADU62_RS11680	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
ADU62_RS11685	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ADU62_RS11690	COG1053	succinate dehydrogenase
ADU62_RS11695	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ADU62_RS11700	COG2009	succinate dehydrogenase
ADU62_RS11705	COG2188	Transcriptional regulator
ADU62_RS11710	COG0039	L-malate dehydrogenase activity
ADU62_RS11740	COG1981	membrane
ADU62_RS11765	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ADU62_RS11775	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ADU62_RS11805	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ADU62_RS11810	COG0148	phosphopyruvate hydratase activity
ADU62_RS11820	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ADU62_RS11825	COG0504	CTP synthase activity
ADU62_RS11850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ADU62_RS11860	COG0747	negative chemotaxis
ADU62_RS11865	COG4172	Belongs to the ABC transporter superfamily
ADU62_RS11870	COG1446	asparaginase
ADU62_RS11900	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ADU62_RS11915	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
ADU62_RS11920	COG0697	spore germination
ADU62_RS11925	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ADU62_RS11935	COG3193	protein, possibly involved in utilization of glycolate and propanediol
ADU62_RS11940	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ADU62_RS11945	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ADU62_RS11950	COG0791	NLP P60 protein
ADU62_RS11965	COG0583	DNA-binding transcription factor activity
ADU62_RS11980	COG0583	DNA-binding transcription factor activity
ADU62_RS11990	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ADU62_RS12005	COG0670	Belongs to the BI1 family
ADU62_RS12010	COG3181	Tripartite tricarboxylate transporter family receptor
ADU62_RS12020	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ADU62_RS12030	COG1381	Involved in DNA repair and RecF pathway recombination
ADU62_RS12035	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ADU62_RS12040	COG0571	ribonuclease III activity
ADU62_RS12045	COG0681	Belongs to the peptidase S26 family
ADU62_RS12050	COG0481	GTPase activity
ADU62_RS12055	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ADU62_RS12080	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ADU62_RS12085	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ADU62_RS12100	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ADU62_RS12105	COG0416	fatty acid biosynthetic process
ADU62_RS12110	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ADU62_RS12115	COG1399	metal-binding, possibly nucleic acid-binding protein
ADU62_RS12120	COG0424	maF-like protein
ADU62_RS12130	COG3023	N-Acetylmuramoyl-L-alanine amidase
ADU62_RS12135	COG1289	transmembrane transporter activity
ADU62_RS12145	COG3022	response to hydroperoxide
ADU62_RS12160	COG0135	phosphoribosylanthranilate isomerase activity
ADU62_RS12175	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ADU62_RS12180	COG0101	tRNA pseudouridine synthase activity
ADU62_RS12190	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ADU62_RS12195	COG0473	3-isopropylmalate dehydrogenase activity
ADU62_RS12200	COG0066	3-isopropylmalate dehydratase activity
ADU62_RS12205	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ADU62_RS12215	COG1122	ATPase activity
ADU62_RS12245	COG0437	4 iron, 4 sulfur cluster binding
ADU62_RS12250	COG3383	formate dehydrogenase (NAD+) activity
ADU62_RS12250	COG0243	molybdopterin cofactor binding
ADU62_RS12280	COG0489	protein tyrosine kinase activity
ADU62_RS12285	COG0746	molybdenum cofactor guanylyltransferase activity
ADU62_RS12290	COG0303	'Molybdopterin
ADU62_RS12295	COG1763	Mo-molybdopterin cofactor biosynthetic process
ADU62_RS12305	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ADU62_RS12310	COG5001	Diguanylate cyclase
ADU62_RS12330	COG3842	ATPase activity
ADU62_RS12340	COG0406	alpha-ribazole phosphatase activity
ADU62_RS12350	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ADU62_RS12355	COG0505	Belongs to the CarA family
ADU62_RS12360	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ADU62_RS12390	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ADU62_RS12395	COG1960	acyl-CoA dehydrogenase activity
ADU62_RS12405	COG2867	negative regulation of translational initiation
ADU62_RS12415	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ADU62_RS12420	COG3706	GGDEF domain
ADU62_RS12425	COG0330	HflC and HflK could
ADU62_RS12440	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ADU62_RS12440	COG0519	Catalyzes the synthesis of GMP from XMP
ADU62_RS12450	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
ADU62_RS12455	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ADU62_RS12460	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ADU62_RS12465	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ADU62_RS12475	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ADU62_RS12480	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ADU62_RS12485	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
ADU62_RS12490	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ADU62_RS12495	COG0750	zinc metalloprotease
ADU62_RS12500	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ADU62_RS12510	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ADU62_RS12515	COG0233	cytoplasmic translational termination
ADU62_RS12520	COG0528	UMP kinase activity
ADU62_RS12525	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ADU62_RS12530	COG0052	Belongs to the universal ribosomal protein uS2 family
ADU62_RS12535	COG0024	Methionine aminopeptidase
ADU62_RS12540	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
ADU62_RS12570	COG0285	dihydrofolate synthase activity
ADU62_RS12605	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ADU62_RS12615	COG1677	Flagellar hook-basal body complex protein FliE
ADU62_RS12625	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ADU62_RS12635	COG1157	protein secretion by the type III secretion system
ADU62_RS12660	COG1580	Controls the rotational direction of flagella during chemotaxis
ADU62_RS12680	COG1338	Plays a role in the flagellum-specific transport system
ADU62_RS12700	COG0840	transmembrane signaling receptor activity
ADU62_RS12705	COG0840	transmembrane signaling receptor activity
ADU62_RS12710	COG0840	transmembrane signaling receptor activity
ADU62_RS12720	COG1256	bacterial-type flagellum assembly
ADU62_RS12730	COG1706	bacterial-type flagellum-dependent cell motility
ADU62_RS12735	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
ADU62_RS12750	COG1749	Flagellar hook protein flgE
ADU62_RS12760	COG1558	bacterial-type flagellum-dependent cell motility
ADU62_RS12765	COG1815	bacterial-type flagellum-dependent cell motility
ADU62_RS12805	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ADU62_RS12810	COG0765	amino acid transport
ADU62_RS12815	COG1126	abc transporter atp-binding protein
ADU62_RS12830	COG4948	Mandelate Racemase Muconate Lactonizing
ADU62_RS12835	COG3181	Tripartite tricarboxylate transporter family receptor
ADU62_RS12845	COG0066	3-isopropylmalate dehydratase activity
ADU62_RS12860	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ADU62_RS12870	COG3181	Tripartite tricarboxylate transporter family receptor
ADU62_RS12880	COG1802	Transcriptional regulator
ADU62_RS12895	COG0583	DNA-binding transcription factor activity
ADU62_RS12915	COG1695	Transcriptional regulator
ADU62_RS12925	COG3568	Endonuclease Exonuclease Phosphatase
ADU62_RS12930	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ADU62_RS12945	COG0392	lysyltransferase activity
ADU62_RS12985	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ADU62_RS12995	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ADU62_RS13015	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
ADU62_RS13045	COG0667	Aldo Keto reductase
ADU62_RS13060	COG2259	Doxx family
ADU62_RS13090	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ADU62_RS13110	COG0386	Belongs to the glutathione peroxidase family
ADU62_RS13115	COG0625	glutathione transferase activity
ADU62_RS13140	COG0688	phosphatidylethanolamine metabolic process
ADU62_RS13150	COG1464	Belongs to the NlpA lipoprotein family
ADU62_RS13165	COG2363	Small membrane protein
ADU62_RS13190	COG3842	ATPase activity
ADU62_RS13195	COG0395	ABC-type sugar transport system, permease component
ADU62_RS13200	COG1175	transmembrane transport
ADU62_RS13205	COG1653	transport
ADU62_RS13215	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ADU62_RS13230	COG0559	Belongs to the binding-protein-dependent transport system permease family
ADU62_RS13250	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ADU62_RS13260	COG2133	pyrroloquinoline quinone binding
ADU62_RS13265	COG2133	pyrroloquinoline quinone binding
ADU62_RS13275	COG0697	spore germination
ADU62_RS13285	COG2311	Membrane
ADU62_RS13310	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ADU62_RS13320	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ADU62_RS13325	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ADU62_RS13330	COG1760	l-serine dehydratase
ADU62_RS13335	COG1283	sodium-dependent phosphate transmembrane transporter activity
ADU62_RS13340	COG0412	Dienelactone hydrolase
ADU62_RS13355	COG1611	Belongs to the LOG family
ADU62_RS13375	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ADU62_RS13380	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ADU62_RS13385	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ADU62_RS13390	COG0195	Participates in both transcription termination and antitermination
ADU62_RS13390	COG2251	uridine kinase activity
ADU62_RS13395	COG0779	Required for maturation of 30S ribosomal subunits
ADU62_RS13400	COG1187	pseudouridine synthase activity
ADU62_RS13405	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ADU62_RS13415	COG0583	DNA-binding transcription factor activity
ADU62_RS13425	COG0523	cobalamin synthesis protein
ADU62_RS13445	COG0625	glutathione transferase activity
ADU62_RS13450	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ADU62_RS13455	COG1047	Peptidyl-prolyl cis-trans
ADU62_RS13460	COG2003	Belongs to the UPF0758 family
ADU62_RS13465	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
ADU62_RS13470	COG3483	tryptophan 2,3-dioxygenase activity
ADU62_RS13475	COG0254	rRNA binding
ADU62_RS13485	COG0534	Mate efflux family protein
ADU62_RS13505	COG2304	oxidoreductase activity
ADU62_RS13525	COG1028	Short-chain dehydrogenase reductase Sdr
ADU62_RS13530	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ADU62_RS13535	COG1562	ergosterol biosynthetic process
ADU62_RS13540	COG1562	ergosterol biosynthetic process
ADU62_RS13545	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
ADU62_RS13545	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
ADU62_RS13550	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ADU62_RS13560	COG0842	Transport permease protein
ADU62_RS13565	COG1131	(ABC) transporter
ADU62_RS13585	COG1477	protein flavinylation
ADU62_RS13600	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
ADU62_RS13615	COG5564	TIM-barrel signal transduction protein
ADU62_RS13620	COG5441	Belongs to the UPF0261 family
ADU62_RS13630	COG3468	outer membrane autotransporter barrel domain protein
ADU62_RS13635	COG3468	outer membrane autotransporter barrel domain protein
ADU62_RS13650	COG0542	response to heat
ADU62_RS13655	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ADU62_RS13670	COG0494	nUDIX hydrolase
ADU62_RS13675	COG3530	Putative quorum-sensing-regulated virulence factor
ADU62_RS13685	COG1595	DNA-templated transcription, initiation
ADU62_RS13690	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ADU62_RS13725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ADU62_RS13730	COG0765	amino acid transport
ADU62_RS13735	COG0765	amino acid transport
ADU62_RS13765	COG2988	succinylglutamate desuccinylase activity
ADU62_RS13790	COG3181	Tripartite tricarboxylate transporter family receptor
ADU62_RS13795	COG2084	Dehydrogenase
ADU62_RS13810	COG1619	proteins homologs of microcin C7 resistance protein MccF
ADU62_RS13825	COG2814	Major facilitator Superfamily
ADU62_RS13835	COG0583	DNA-binding transcription factor activity
ADU62_RS13875	COG0672	)-iron permease
ADU62_RS13890	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
ADU62_RS13895	COG1028	Short-chain dehydrogenase reductase Sdr
ADU62_RS13900	COG3243	poly(R)-hydroxyalkanoic acid synthase
ADU62_RS13910	COG0564	pseudouridine synthase activity
ADU62_RS13920	COG1199	ATP-dependent helicase activity
ADU62_RS13925	COG2183	response to ionizing radiation
ADU62_RS13930	COG0180	Tryptophanyl-tRNA synthetase
ADU62_RS13955	COG3181	Tripartite tricarboxylate transporter family receptor
ADU62_RS13965	COG0583	DNA-binding transcription factor activity
ADU62_RS13970	COG1028	Short-chain dehydrogenase reductase Sdr
ADU62_RS13975	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ADU62_RS13980	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ADU62_RS13985	COG0508	dehydrogenase complex catalyzes the overall conversion of
ADU62_RS13990	COG0567	Dehydrogenase, E1 component
ADU62_RS14000	COG1522	sequence-specific DNA binding
ADU62_RS14010	COG0280	phosphate acetyltransferase
ADU62_RS14010	COG0281	malic enzyme
ADU62_RS14015	COG3539	Fimbrial protein
ADU62_RS14030	COG0613	PHP domain protein
ADU62_RS14040	COG0658	competence protein
ADU62_RS14040	COG2333	competence protein COMEC
ADU62_RS14070	COG0084	hydrolase, TatD family'
ADU62_RS14075	COG1136	(ABC) transporter
ADU62_RS14090	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ADU62_RS14100	COG1028	Short-chain dehydrogenase reductase Sdr
ADU62_RS14105	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ADU62_RS14120	COG1022	Amp-dependent synthetase and ligase
ADU62_RS14155	COG2205	protein histidine kinase activity
ADU62_RS14160	COG0745	RESPONSE REGULATOR receiver
ADU62_RS14165	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ADU62_RS14175	COG1295	ribonuclease BN
ADU62_RS14190	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ADU62_RS14220	COG1534	Rna-binding protein
ADU62_RS14225	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
ADU62_RS14230	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ADU62_RS14240	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ADU62_RS14250	COG0248	Ppx GppA phosphatase
ADU62_RS14275	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ADU62_RS14290	COG2732	(Barnase) inhibitor
ADU62_RS14300	COG0280	phosphate acetyltransferase
ADU62_RS14300	COG0281	malic enzyme
ADU62_RS14310	COG0436	Aminotransferase
ADU62_RS14315	COG0741	lytic transglycosylase activity
ADU62_RS14320	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ADU62_RS14345	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ADU62_RS14345	COG1648	precorrin-2 dehydrogenase activity
ADU62_RS14350	COG3468	outer membrane autotransporter barrel domain protein
ADU62_RS14360	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ADU62_RS14365	COG2027	D-alanyl-D-alanine carboxypeptidase
ADU62_RS14370	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ADU62_RS14375	COG0343	queuine tRNA-ribosyltransferase activity
ADU62_RS14380	COG1862	Preprotein translocase
ADU62_RS14385	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ADU62_RS14390	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ADU62_RS14405	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ADU62_RS14410	COG1702	phosphate starvation-inducible protein PhoH
ADU62_RS14415	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ADU62_RS14420	COG4535	Mg2 and Co2 transporter CorC
ADU62_RS14430	COG0667	Aldo Keto reductase
ADU62_RS14455	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
ADU62_RS14460	COG0745	RESPONSE REGULATOR receiver
ADU62_RS14465	COG2201	protein-glutamate methylesterase activity
ADU62_RS14475	COG0840	transmembrane signaling receptor activity
ADU62_RS14490	COG0745	RESPONSE REGULATOR receiver
ADU62_RS14525	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ADU62_RS14535	COG0739	heme binding
ADU62_RS14545	COG0521	Mo-molybdopterin cofactor biosynthetic process
ADU62_RS14555	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ADU62_RS14590	COG0625	glutathione transferase activity
ADU62_RS14605	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ADU62_RS14610	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ADU62_RS14615	COG0126	phosphoglycerate kinase activity
ADU62_RS14620	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ADU62_RS14625	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ADU62_RS14630	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ADU62_RS14640	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ADU62_RS14645	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ADU62_RS14650	COG0508	dehydrogenase complex catalyzes the overall conversion of
ADU62_RS14655	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ADU62_RS14665	COG4566	intracellular signal transduction
ADU62_RS14670	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ADU62_RS14675	COG0339	signal peptide processing
ADU62_RS14680	COG1999	signal sequence binding
ADU62_RS14700	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ADU62_RS14710	COG1187	pseudouridine synthase activity
ADU62_RS14715	COG3161	chorismate lyase activity
ADU62_RS14720	COG2814	Major facilitator Superfamily
ADU62_RS14730	COG0667	Aldo Keto reductase
ADU62_RS14745	COG0335	large ribosomal subunit rRNA binding
ADU62_RS14775	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ADU62_RS14780	COG4208	sulfate ABC transporter
ADU62_RS14785	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ADU62_RS14800	COG0450	alkyl hydroperoxide reductase
ADU62_RS14805	COG1960	acyl-CoA dehydrogenase activity
ADU62_RS14820	COG0123	including yeast histone deacetylase and acetoin utilization protein
ADU62_RS14825	COG2951	lytic endotransglycosylase activity
ADU62_RS14840	COG1596	polysaccharide export
ADU62_RS14840	COG1555	photosystem II stabilization
ADU62_RS14845	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ADU62_RS14850	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ADU62_RS14855	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ADU62_RS14875	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ADU62_RS14880	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ADU62_RS14885	COG0287	Prephenate dehydrogenase
ADU62_RS14895	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ADU62_RS14910	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ADU62_RS14920	COG2814	Major facilitator Superfamily
ADU62_RS14945	COG0583	DNA-binding transcription factor activity
ADU62_RS14985	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ADU62_RS15000	COG0667	Aldo Keto reductase
ADU62_RS15010	COG5265	(ABC) transporter
ADU62_RS15055	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ADU62_RS15060	COG0439	Biotin carboxylase
ADU62_RS15065	COG2188	Transcriptional regulator
ADU62_RS15090	COG0511	ligase activity, forming carbon-carbon bonds
ADU62_RS15100	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ADU62_RS15120	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
ADU62_RS15140	COG0500	methyltransferase
ADU62_RS15145	COG5265	(ABC) transporter
ADU62_RS15160	COG0028	Belongs to the TPP enzyme family
ADU62_RS15165	COG0440	acetolactate synthase activity
ADU62_RS15170	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ADU62_RS15175	COG1183	phosphatidylcholine synthase activity
ADU62_RS15190	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ADU62_RS15195	COG1185	polyribonucleotide nucleotidyltransferase activity
ADU62_RS15210	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ADU62_RS15230	COG0149	triose-phosphate isomerase activity
ADU62_RS15235	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ADU62_RS15245	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ADU62_RS15255	COG3799	methylaspartate ammonia-lyase activity
ADU62_RS15290	COG0583	DNA-binding transcription factor activity
ADU62_RS15295	COG0626	cystathionine gamma-synthase activity
ADU62_RS15300	COG3608	succinylglutamate desuccinylase aspartoacylase
ADU62_RS15320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ADU62_RS15340	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
ADU62_RS15355	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ADU62_RS15360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ADU62_RS15365	COG1733	regulation of RNA biosynthetic process
ADU62_RS15375	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ADU62_RS15380	COG0583	DNA-binding transcription factor activity
ADU62_RS15385	COG1597	lipid kinase activity
ADU62_RS15395	COG0671	phosphoesterase, PA-phosphatase related
ADU62_RS15420	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ADU62_RS15425	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ADU62_RS15430	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ADU62_RS15435	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ADU62_RS15440	COG0649	NAD binding
ADU62_RS15445	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
ADU62_RS15455	COG1034	ATP synthesis coupled electron transport
ADU62_RS15460	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ADU62_RS15465	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ADU62_RS15475	COG0713	ATP synthesis coupled electron transport
ADU62_RS15490	COG1007	ATP synthesis coupled electron transport
ADU62_RS15500	COG4774	siderophore transport
ADU62_RS15505	COG4774	siderophore transport
ADU62_RS15520	COG0028	Belongs to the TPP enzyme family
ADU62_RS15525	COG3181	Tripartite tricarboxylate transporter family receptor
ADU62_RS15530	COG0583	DNA-binding transcription factor activity
ADU62_RS15535	COG0560	Phosphoserine phosphatase
ADU62_RS15540	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ADU62_RS15545	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ADU62_RS15550	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ADU62_RS15565	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ADU62_RS15570	COG0308	aminopeptidase N
ADU62_RS15590	COG0028	Belongs to the TPP enzyme family
ADU62_RS15610	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ADU62_RS15620	COG0318	PFAM AMP-dependent synthetase and ligase
ADU62_RS15630	COG1802	Transcriptional regulator
ADU62_RS15640	COG1802	Transcriptional regulator
ADU62_RS15650	COG1028	Short-chain dehydrogenase reductase Sdr
ADU62_RS15670	COG1126	abc transporter atp-binding protein
ADU62_RS15675	COG0765	amino acid transport
ADU62_RS15680	COG0765	amino acid transport
ADU62_RS15695	COG1538	Outer membrane efflux protein
ADU62_RS15700	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ADU62_RS15705	COG2274	protein secretion by the type I secretion system
ADU62_RS15710	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
ADU62_RS15720	COG2994	toxin metabolic process
ADU62_RS15735	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ADU62_RS15740	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
ADU62_RS15750	COG0583	DNA-binding transcription factor activity
ADU62_RS15760	COG0142	geranyltranstransferase activity
ADU62_RS15770	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ADU62_RS15775	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ADU62_RS15780	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ADU62_RS15785	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ADU62_RS15830	COG3712	iron ion homeostasis
ADU62_RS15835	COG4774	siderophore transport
ADU62_RS15840	COG2353	YceI-like domain
ADU62_RS15855	COG0019	diaminopimelate decarboxylase activity
ADU62_RS15875	COG0747	negative chemotaxis
ADU62_RS15880	COG0601	transmembrane transport
ADU62_RS15885	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ADU62_RS15895	COG0154	amidase activity
ADU62_RS15900	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ADU62_RS15925	COG2154	pterin-4-alpha-carbinolamine dehydratase
ADU62_RS15935	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ADU62_RS15945	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ADU62_RS15950	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ADU62_RS15955	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ADU62_RS15960	COG1929	Belongs to the glycerate kinase type-1 family
ADU62_RS15965	COG0469	pyruvate kinase activity
ADU62_RS15970	COG0700	Nucleoside recognition
ADU62_RS16005	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
ADU62_RS16010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ADU62_RS16025	COG0823	Involved in the tonB-independent uptake of proteins
ADU62_RS16035	COG0848	biopolymer transport protein
ADU62_RS16040	COG0811	peptide transport
ADU62_RS16045	COG0824	Thioesterase
ADU62_RS16050	COG0442	prolyl-tRNA aminoacylation
ADU62_RS16055	COG0494	nUDIX hydrolase
ADU62_RS16070	COG2135	peptidase activity
ADU62_RS16140	COG1196	nuclear chromosome segregation
ADU62_RS16285	COG1464	Belongs to the NlpA lipoprotein family
ADU62_RS16315	COG4211	Belongs to the binding-protein-dependent transport system permease family
ADU62_RS16325	COG0154	amidase activity
ADU62_RS16330	COG0288	reversible hydration of carbon dioxide
ADU62_RS16345	COG0514	ATP-dependent DNA helicase (RecQ)
ADU62_RS16350	COG2255	four-way junction helicase activity
ADU62_RS16365	COG0632	four-way junction helicase activity
ADU62_RS16370	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ADU62_RS16390	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ADU62_RS16400	COG0006	proline dipeptidase activity
ADU62_RS16425	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ADU62_RS16440	COG4783	chaperone-mediated protein folding
ADU62_RS16445	COG0429	hydrolase of the alpha beta-hydrolase fold
ADU62_RS16475	COG0513	Belongs to the DEAD box helicase family
ADU62_RS16495	COG1546	Belongs to the CinA family
ADU62_RS16495	COG1058	Belongs to the CinA family
ADU62_RS16500	COG1414	Transcriptional regulator
ADU62_RS16520	COG0167	dihydroorotate dehydrogenase activity
ADU62_RS16525	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
ADU62_RS16530	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ADU62_RS16540	COG0583	DNA-binding transcription factor activity
ADU62_RS16600	COG0280	phosphate acetyltransferase
ADU62_RS16600	COG0281	malic enzyme
ADU62_RS16610	COG0601	transmembrane transport
ADU62_RS16615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ADU62_RS16620	COG4172	Belongs to the ABC transporter superfamily
ADU62_RS16650	COG0640	Transcriptional regulator
ADU62_RS16665	COG3135	benzoate transporter
ADU62_RS16670	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ADU62_RS16675	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ADU62_RS16680	COG0742	ribosomal rna small subunit methyltransferase
ADU62_RS16695	COG3639	organic phosphonate transmembrane transporter activity
ADU62_RS16700	COG3639	organic phosphonate transmembrane transporter activity
ADU62_RS16705	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
ADU62_RS16740	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ADU62_RS16745	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ADU62_RS16755	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ADU62_RS16760	COG1546	Belongs to the CinA family
ADU62_RS16760	COG1058	Belongs to the CinA family
ADU62_RS16765	COG0284	orotidine-5'-phosphate decarboxylase activity
ADU62_RS16770	COG1252	NADH dehydrogenase
ADU62_RS16785	COG3468	outer membrane autotransporter barrel domain protein
ADU62_RS16790	COG0459	protein refolding
ADU62_RS16795	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ADU62_RS16815	COG1053	succinate dehydrogenase
ADU62_RS16825	COG0583	DNA-binding transcription factor activity
ADU62_RS16830	COG1053	succinate dehydrogenase
ADU62_RS16855	COG3706	GGDEF domain
ADU62_RS16890	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ADU62_RS16895	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
ADU62_RS16905	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ADU62_RS16915	COG0069	glutamate synthase activity
ADU62_RS16920	COG2391	methyltransferase activity
ADU62_RS16925	COG0679	Auxin Efflux Carrier
ADU62_RS16950	COG0557	exoribonuclease II activity
ADU62_RS16955	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ADU62_RS16965	COG3128	pkhd-type hydroxylase
ADU62_RS16970	COG0776	regulation of translation
ADU62_RS17000	COG0642	Histidine kinase
ADU62_RS17005	COG3158	transport of potassium into the cell
ADU62_RS17010	COG0137	argininosuccinate synthase activity
ADU62_RS17015	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ADU62_RS17020	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ADU62_RS17030	COG0583	DNA-binding transcription factor activity
ADU62_RS17040	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ADU62_RS17060	COG2186	Transcriptional regulator
ADU62_RS17070	COG2223	nitrite transmembrane transporter activity
ADU62_RS17080	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ADU62_RS17085	COG0450	alkyl hydroperoxide reductase
ADU62_RS17105	COG1214	PFAM Peptidase M22, glycoprotease
ADU62_RS17110	COG1573	uracil-dna glycosylase
ADU62_RS17115	COG0477	Major facilitator Superfamily
ADU62_RS17120	COG1196	nuclear chromosome segregation
ADU62_RS17130	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ADU62_RS17135	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ADU62_RS17150	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ADU62_RS17155	COG1122	ATPase activity
ADU62_RS17160	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ADU62_RS17165	COG1268	BioY protein
ADU62_RS17185	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ADU62_RS17220	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ADU62_RS17225	COG2878	Part of a membrane complex involved in electron transport
ADU62_RS17240	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ADU62_RS17245	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ADU62_RS17250	COG0251	oxidation-reduction process
ADU62_RS17260	COG3228	Belongs to the MtfA family
ADU62_RS17265	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ADU62_RS17275	COG0133	tryptophan synthase activity
ADU62_RS17280	COG0159	tryptophan synthase activity
ADU62_RS17285	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ADU62_RS17290	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
ADU62_RS17305	COG1530	ribonuclease E activity
ADU62_RS17315	COG0546	phosphoglycolate phosphatase activity
ADU62_RS17320	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ADU62_RS17325	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
ADU62_RS17335	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ADU62_RS17340	COG0583	DNA-binding transcription factor activity
ADU62_RS17350	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ADU62_RS17370	COG0251	oxidation-reduction process
ADU62_RS17375	COG1017	nitric oxide dioxygenase activity
ADU62_RS17375	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ADU62_RS17380	COG2031	fatty acid transporter
ADU62_RS17385	COG1012	belongs to the aldehyde dehydrogenase family
ADU62_RS17390	COG1802	Transcriptional regulator
ADU62_RS17400	COG1278	Cold shock
ADU62_RS17405	COG0583	DNA-binding transcription factor activity
ADU62_RS17425	COG0183	Belongs to the thiolase family
ADU62_RS17435	COG1960	acyl-CoA dehydrogenase activity
ADU62_RS17440	COG0583	DNA-binding transcription factor activity
ADU62_RS17445	COG3181	Tripartite tricarboxylate transporter family receptor
ADU62_RS17450	COG1024	Enoyl-CoA hydratase
ADU62_RS17455	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ADU62_RS17460	COG1253	flavin adenine dinucleotide binding
ADU62_RS17465	COG1285	pathogenesis
ADU62_RS17475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ADU62_RS17490	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ADU62_RS17500	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ADU62_RS17510	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ADU62_RS17515	COG3181	Tripartite tricarboxylate transporter family receptor
ADU62_RS17520	COG1960	acyl-CoA dehydrogenase activity
ADU62_RS17540	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ADU62_RS17545	COG1024	Enoyl-CoA hydratase
ADU62_RS17550	COG1960	acyl-CoA dehydrogenase activity
ADU62_RS17570	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ADU62_RS17575	COG0022	dehydrogenase e1 component
ADU62_RS17580	COG1024	Enoyl-CoA hydratase
ADU62_RS17585	COG0508	dehydrogenase complex catalyzes the overall conversion of
ADU62_RS17605	COG0683	leucine binding
ADU62_RS17610	COG0559	Belongs to the binding-protein-dependent transport system permease family
ADU62_RS17615	COG0411	ABC transporter
ADU62_RS17625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ADU62_RS17640	COG3181	Tripartite tricarboxylate transporter family receptor
ADU62_RS17670	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ADU62_RS17675	COG0793	Belongs to the peptidase S41A family
ADU62_RS17680	COG4942	peptidase
ADU62_RS17685	COG0588	phosphoglycerate mutase activity
ADU62_RS17690	COG1054	Belongs to the UPF0176 family
ADU62_RS17695	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ADU62_RS17700	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
ADU62_RS17705	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ADU62_RS17710	COG3181	Tripartite tricarboxylate transporter family receptor
ADU62_RS17725	COG2226	methyltransferase
ADU62_RS17730	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ADU62_RS17745	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ADU62_RS17750	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ADU62_RS17775	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ADU62_RS17800	COG1335	isochorismatase
ADU62_RS17805	COG2309	aminopeptidase activity
ADU62_RS17810	COG0596	Alpha beta hydrolase
ADU62_RS17815	COG3473	Maleate cis-trans isomerase
ADU62_RS17825	COG2068	MobA-Related Protein
ADU62_RS17850	COG2204	response regulator
ADU62_RS17855	COG5000	phosphorelay sensor kinase activity
ADU62_RS17865	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ADU62_RS17865	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ADU62_RS17875	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
ADU62_RS17905	COG0583	DNA-binding transcription factor activity
ADU62_RS17920	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ADU62_RS17925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ADU62_RS17930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ADU62_RS17945	COG0758	DNA mediated transformation
ADU62_RS17950	COG1522	sequence-specific DNA binding
ADU62_RS17960	COG0242	peptide deformylase activity
ADU62_RS17975	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ADU62_RS17985	COG0546	phosphoglycolate phosphatase activity
ADU62_RS18005	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ADU62_RS18010	COG1942	4-Oxalocrotonate Tautomerase
ADU62_RS18015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ADU62_RS18040	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ADU62_RS18060	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ADU62_RS18065	COG1024	Enoyl-CoA hydratase
ADU62_RS18070	COG1414	Transcriptional regulator
ADU62_RS18075	COG0318	PFAM AMP-dependent synthetase and ligase
ADU62_RS18080	COG3181	Tripartite tricarboxylate transporter family receptor
ADU62_RS18110	COG0583	DNA-binding transcription factor activity
ADU62_RS18125	COG3422	double-strand break repair
ADU62_RS18130	COG0330	HflC and HflK could
ADU62_RS18140	COG0251	oxidation-reduction process
ADU62_RS18185	COG3723	Recombinational DNA repair protein, rece pathway
ADU62_RS18220	COG0582	viral genome integration into host DNA
ADU62_RS18245	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ADU62_RS18255	COG0706	membrane insertase activity
ADU62_RS18260	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ADU62_RS18265	COG0594	ribonuclease P activity
ADU62_RS18270	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ADU62_RS18275	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ADU62_RS18290	COG1414	Transcriptional regulator
ADU62_RS18295	COG0154	amidase activity
ADU62_RS18310	COG1304	FMN binding
ADU62_RS18330	COG1960	acyl-CoA dehydrogenase activity
ADU62_RS18350	COG1960	acyl-CoA dehydrogenase activity
ADU62_RS18365	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ADU62_RS18380	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ADU62_RS18385	COG3181	Tripartite tricarboxylate transporter family receptor
ADU62_RS18395	COG2358	TRAP transporter, solute receptor (TAXI family
ADU62_RS18405	COG1629	transport
ADU62_RS18410	COG2922	Belongs to the Smg family
ADU62_RS18435	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ADU62_RS18440	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ADU62_RS18445	COG1028	Short-chain dehydrogenase reductase Sdr
ADU62_RS18450	COG1012	belongs to the aldehyde dehydrogenase family
ADU62_RS18460	COG0028	Belongs to the TPP enzyme family
ADU62_RS18465	COG1522	sequence-specific DNA binding
ADU62_RS18470	COG3781	membrane
ADU62_RS18480	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ADU62_RS18500	COG4206	TonB-dependent receptor
ADU62_RS18505	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ADU62_RS18510	COG2022	thiamine diphosphate biosynthetic process
ADU62_RS18515	COG0351	phosphomethylpyrimidine kinase
ADU62_RS18520	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ADU62_RS18535	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ADU62_RS18545	COG0628	permease
ADU62_RS18555	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ADU62_RS18565	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ADU62_RS18570	COG0049	tRNA binding
ADU62_RS18575	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ADU62_RS18580	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ADU62_RS18585	COG0051	transcription antitermination factor activity, RNA binding
ADU62_RS18590	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ADU62_RS18595	COG0088	Forms part of the polypeptide exit tunnel
ADU62_RS18600	COG0089	rRNA binding
ADU62_RS18605	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ADU62_RS18610	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ADU62_RS18615	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ADU62_RS18620	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ADU62_RS18625	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ADU62_RS18630	COG0255	Belongs to the universal ribosomal protein uL29 family
ADU62_RS18635	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ADU62_RS18655	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ADU62_RS18660	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ADU62_RS18665	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ADU62_RS18670	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ADU62_RS18675	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ADU62_RS18680	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ADU62_RS18685	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ADU62_RS18690	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ADU62_RS18695	COG1841	ribosomal large subunit assembly
ADU62_RS18700	COG0200	Binds to the 23S rRNA
ADU62_RS18705	COG0201	protein transport
ADU62_RS18710	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ADU62_RS18715	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ADU62_RS18720	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ADU62_RS18725	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ADU62_RS18730	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ADU62_RS18735	COG0202	RNA polymerase activity
ADU62_RS18740	COG0203	ribosomal protein L17
ADU62_RS18745	COG0537	adenosine 5'-monophosphoramidase activity
ADU62_RS18750	COG1324	tolerance protein
ADU62_RS18755	COG4232	protein-disulfide reductase activity
ADU62_RS18770	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ADU62_RS18780	COG1333	cytochrome c biogenesis protein
ADU62_RS18785	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ADU62_RS18800	COG1965	Belongs to the frataxin family
ADU62_RS18810	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ADU62_RS18815	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ADU62_RS18820	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ADU62_RS18835	COG2814	Major facilitator Superfamily
ADU62_RS18840	COG0629	single-stranded DNA binding
ADU62_RS18880	COG0402	S-adenosylhomocysteine deaminase activity
ADU62_RS18890	COG0438	transferase activity, transferring glycosyl groups
ADU62_RS18910	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ADU62_RS18935	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ADU62_RS18940	COG2186	Transcriptional regulator
ADU62_RS18960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ADU62_RS18965	COG1956	GAF domain-containing protein
ADU62_RS18970	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ADU62_RS18985	COG1652	LysM domain
ADU62_RS19000	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ADU62_RS19015	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ADU62_RS19045	COG3181	Tripartite tricarboxylate transporter family receptor
ADU62_RS19060	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ADU62_RS19075	COG1024	Enoyl-CoA hydratase
ADU62_RS19090	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ADU62_RS19095	COG1309	transcriptional regulator
ADU62_RS19100	COG2816	NAD+ diphosphatase activity
ADU62_RS19105	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ADU62_RS19190	COG2814	Major facilitator Superfamily
ADU62_RS19195	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ADU62_RS19215	COG1999	signal sequence binding
ADU62_RS19220	COG0109	protoheme IX farnesyltransferase activity
ADU62_RS19260	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ADU62_RS19280	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ADU62_RS19285	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ADU62_RS19295	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
ADU62_RS19300	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
ADU62_RS19310	COG0070	glutamate synthase
ADU62_RS19310	COG0067	glutamate synthase
ADU62_RS19310	COG0069	glutamate synthase activity
ADU62_RS19320	COG3047	cAMP biosynthetic process
ADU62_RS19330	COG1127	ABC transporter
ADU62_RS19335	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ADU62_RS19340	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ADU62_RS19345	COG2853	Lipoprotein
ADU62_RS19355	COG1131	(ABC) transporter
ADU62_RS19360	COG0842	Transport permease protein
ADU62_RS19370	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ADU62_RS19375	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ADU62_RS19380	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ADU62_RS19385	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ADU62_RS19390	COG0131	Imidazoleglycerol-phosphate dehydratase
ADU62_RS19395	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ADU62_RS19400	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ADU62_RS19405	COG0107	imidazoleglycerol-phosphate synthase activity
ADU62_RS19410	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ADU62_RS19415	COG0140	phosphoribosyl-ATP diphosphatase activity
ADU62_RS19420	COG0537	adenosine 5'-monophosphoramidase activity
ADU62_RS19425	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ADU62_RS19430	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ADU62_RS19445	COG3181	Tripartite tricarboxylate transporter family receptor
ADU62_RS19480	COG3702	type iv secretory pathway
ADU62_RS19485	COG3451	type IV secretory pathway VirB4
ADU62_RS19500	COG3736	Type IV secretory pathway, component VirB8
ADU62_RS19505	COG3504	Conjugal transfer protein
ADU62_RS19510	COG2948	multi-organism process
ADU62_RS19515	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
ADU62_RS19525	COG0697	spore germination
ADU62_RS19545	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ADU62_RS19550	COG0747	negative chemotaxis
ADU62_RS19555	COG0601	transmembrane transport
ADU62_RS19560	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ADU62_RS19565	COG0444	Belongs to the ABC transporter superfamily
ADU62_RS19575	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ADU62_RS19585	COG0494	nUDIX hydrolase
ADU62_RS19625	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
ADU62_RS19630	COG0237	dephospho-CoA kinase activity
ADU62_RS19635	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ADU62_RS19650	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ADU62_RS19655	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ADU62_RS19665	COG0477	Major facilitator Superfamily
ADU62_RS19670	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ADU62_RS19685	COG1126	abc transporter atp-binding protein
ADU62_RS19690	COG0765	amino acid transport
ADU62_RS19695	COG4597	amino acid ABC transporter
ADU62_RS19700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ADU62_RS19705	COG2884	Cell division ATP-binding protein ftsE
ADU62_RS19710	COG2177	Part of the ABC transporter FtsEX involved in
ADU62_RS19715	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ADU62_RS19725	COG1194	a g-specific adenine glycosylase
ADU62_RS19735	COG2226	methyltransferase
ADU62_RS19745	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ADU62_RS19750	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ADU62_RS19765	COG1024	Enoyl-CoA hydratase
ADU62_RS19785	COG1024	Enoyl-CoA hydratase
ADU62_RS19790	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ADU62_RS19795	COG3181	Tripartite tricarboxylate transporter family receptor
ADU62_RS19805	COG0753	catalase activity
ADU62_RS19810	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ADU62_RS19815	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ADU62_RS19825	COG2175	clavaminate synthase activity
ADU62_RS19830	COG1473	amidohydrolase
ADU62_RS19835	COG4608	Belongs to the ABC transporter superfamily
ADU62_RS19840	COG0444	Belongs to the ABC transporter superfamily
ADU62_RS19855	COG0747	negative chemotaxis
ADU62_RS19860	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ADU62_RS19895	COG0436	Aminotransferase
ADU62_RS19900	COG1278	Cold shock