locus-tag	class	description
AVS47_RS00005	COG0445	tRNA wobble uridine modification
AVS47_RS00010	COG0357	Ribosomal RNA small subunit methyltransferase G
AVS47_RS00015	COG1192	Involved in chromosome partitioning
AVS47_RS00025	COG1475	DNA binding
AVS47_RS00030	COG0252	asparaginase activity
AVS47_RS00055	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AVS47_RS00065	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AVS47_RS00075	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AVS47_RS00080	COG0081	regulation of translation
AVS47_RS00085	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AVS47_RS00090	COG0222	ribosome binding
AVS47_RS00095	COG0085	RNA polymerase activity
AVS47_RS00100	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AVS47_RS00140	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AVS47_RS00165	COG1024	Enoyl-CoA hydratase
AVS47_RS00185	COG0752	glycyl-tRNA synthetase alpha subunit
AVS47_RS00190	COG0751	glycine-tRNA ligase activity
AVS47_RS00195	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AVS47_RS00200	COG0204	Acyl-transferase
AVS47_RS00215	COG0242	peptide deformylase activity
AVS47_RS00250	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AVS47_RS00265	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AVS47_RS00270	COG2813	Specifically methylates the guanine in position
AVS47_RS00270	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AVS47_RS00285	COG2223	nitrite transmembrane transporter activity
AVS47_RS00295	COG1794	racemase activity, acting on amino acids and derivatives
AVS47_RS00300	COG1126	abc transporter atp-binding protein
AVS47_RS00305	COG0765	amino acid transport
AVS47_RS00310	COG0765	amino acid transport
AVS47_RS00315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVS47_RS00380	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AVS47_RS00410	COG0326	Molecular chaperone. Has ATPase activity
AVS47_RS00415	COG0625	glutathione transferase activity
AVS47_RS00430	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AVS47_RS00435	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AVS47_RS00465	COG0438	transferase activity, transferring glycosyl groups
AVS47_RS00470	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AVS47_RS00475	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AVS47_RS00505	COG0859	PFAM glycosyl transferase family 9
AVS47_RS00520	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AVS47_RS00530	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AVS47_RS00535	COG1127	ABC transporter
AVS47_RS00555	COG1686	Belongs to the peptidase S11 family
AVS47_RS00565	COG2921	Belongs to the UPF0250 family
AVS47_RS00570	COG0321	lipoyl(octanoyl) transferase activity
AVS47_RS00575	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AVS47_RS00610	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AVS47_RS00620	COG0018	arginyl-trna synthetase
AVS47_RS00640	COG0395	ABC-type sugar transport system, permease component
AVS47_RS00645	COG1175	transmembrane transport
AVS47_RS00650	COG1653	transport
AVS47_RS00655	COG3842	ATPase activity
AVS47_RS00660	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AVS47_RS00670	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AVS47_RS00690	COG1609	Transcriptional regulator
AVS47_RS00700	COG0154	amidase activity
AVS47_RS00705	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AVS47_RS00715	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AVS47_RS00725	COG0583	DNA-binding transcription factor activity
AVS47_RS00740	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AVS47_RS00745	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AVS47_RS00760	COG1802	Transcriptional regulator
AVS47_RS00775	COG1024	Enoyl-CoA hydratase
AVS47_RS00785	COG3181	Tripartite tricarboxylate transporter family receptor
AVS47_RS00800	COG1984	allophanate hydrolase subunit 2
AVS47_RS00805	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AVS47_RS00815	COG0583	DNA-binding transcription factor activity
AVS47_RS00820	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AVS47_RS00830	COG5002	protein histidine kinase activity
AVS47_RS00840	COG5002	protein histidine kinase activity
AVS47_RS00845	COG0745	RESPONSE REGULATOR receiver
AVS47_RS00850	COG2226	methyltransferase
AVS47_RS00865	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AVS47_RS00885	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AVS47_RS00895	COG0513	Belongs to the DEAD box helicase family
AVS47_RS00900	COG1280	lysine exporter protein (LysE YggA)
AVS47_RS00905	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AVS47_RS00940	COG1054	Belongs to the UPF0176 family
AVS47_RS00945	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AVS47_RS00945	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AVS47_RS00955	COG0489	protein tyrosine kinase activity
AVS47_RS00970	COG0717	Belongs to the dCTP deaminase family
AVS47_RS01000	COG2081	HI0933 family
AVS47_RS01010	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AVS47_RS01020	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AVS47_RS01025	COG0509	glycine decarboxylation via glycine cleavage system
AVS47_RS01030	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AVS47_RS01030	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AVS47_RS01070	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AVS47_RS01085	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AVS47_RS01095	COG1414	Transcriptional regulator
AVS47_RS01100	COG1028	Short-chain dehydrogenase reductase Sdr
AVS47_RS01105	COG2031	fatty acid transporter
AVS47_RS01110	COG1250	3-hydroxyacyl-CoA dehydrogenase
AVS47_RS01120	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AVS47_RS01125	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AVS47_RS01135	COG4257	antibiotic catabolic process
AVS47_RS01160	COG1012	belongs to the aldehyde dehydrogenase family
AVS47_RS01165	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AVS47_RS01170	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AVS47_RS01195	COG1028	Short-chain dehydrogenase reductase Sdr
AVS47_RS01205	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AVS47_RS01220	COG2188	Transcriptional regulator
AVS47_RS01225	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AVS47_RS01250	COG0617	tRNA 3'-terminal CCA addition
AVS47_RS01265	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AVS47_RS01270	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AVS47_RS01275	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AVS47_RS01280	COG0586	Pfam SNARE associated Golgi protein
AVS47_RS01285	COG0860	N-Acetylmuramoyl-L-alanine amidase
AVS47_RS01290	COG0802	atpase or kinase
AVS47_RS01295	COG0114	fumarate hydratase activity
AVS47_RS01305	COG3181	Tripartite tricarboxylate transporter family receptor
AVS47_RS01315	COG0405	Gamma-glutamyltransferase
AVS47_RS01320	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AVS47_RS01330	COG1960	acyl-CoA dehydrogenase activity
AVS47_RS01355	COG1294	oxidase, subunit
AVS47_RS01365	COG4988	ABC transporter
AVS47_RS01370	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AVS47_RS01375	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AVS47_RS01390	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AVS47_RS01420	COG2969	positive regulation of protein catabolic process
AVS47_RS01425	COG0625	glutathione transferase activity
AVS47_RS01430	COG2857	Cytochrome c1
AVS47_RS01435	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AVS47_RS01440	COG0723	plastoquinol--plastocyanin reductase activity
AVS47_RS01445	COG1970	mechanosensitive ion channel activity
AVS47_RS01450	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AVS47_RS01465	COG2808	Putative FMN-binding domain
AVS47_RS01470	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AVS47_RS01475	COG0747	negative chemotaxis
AVS47_RS01480	COG0657	acetylesterase activity
AVS47_RS01490	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AVS47_RS01495	COG2207	Transcriptional regulator
AVS47_RS01500	COG0129	dihydroxy-acid dehydratase activity
AVS47_RS01505	COG2814	Major facilitator Superfamily
AVS47_RS01510	COG0583	DNA-binding transcription factor activity
AVS47_RS01520	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
AVS47_RS01590	COG1024	Enoyl-CoA hydratase
AVS47_RS01595	COG1960	acyl-CoA dehydrogenase activity
AVS47_RS01620	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AVS47_RS01625	COG0352	thiamine-phosphate diphosphorylase activity
AVS47_RS01640	COG1678	Uncharacterized ACR, COG1678
AVS47_RS01645	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AVS47_RS01650	COG0540	Belongs to the ATCase OTCase family
AVS47_RS01665	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AVS47_RS01675	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AVS47_RS01710	COG1234	tRNA 3'-trailer cleavage
AVS47_RS01730	COG3064	Membrane
AVS47_RS01760	COG1683	Conserved Protein
AVS47_RS01765	COG1120	ATPase activity
AVS47_RS01770	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AVS47_RS01775	COG4558	Periplasmic binding protein
AVS47_RS01780	COG3720	iron ion transport
AVS47_RS01790	COG3712	iron ion homeostasis
AVS47_RS01795	COG1595	DNA-templated transcription, initiation
AVS47_RS01830	COG1802	Transcriptional regulator
AVS47_RS01840	COG3069	C4-dicarboxylate transmembrane transporter activity
AVS47_RS01850	COG1012	belongs to the aldehyde dehydrogenase family
AVS47_RS01885	COG2860	membrane
AVS47_RS01890	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AVS47_RS01895	COG0708	Exodeoxyribonuclease III
AVS47_RS01900	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AVS47_RS01905	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AVS47_RS01910	COG0154	amidase activity
AVS47_RS01915	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AVS47_RS01920	COG1077	Cell shape determining protein MreB Mrl
AVS47_RS01925	COG1792	Involved in formation and maintenance of cell shape
AVS47_RS01935	COG0768	penicillin binding
AVS47_RS01940	COG0772	Belongs to the SEDS family
AVS47_RS01945	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AVS47_RS01950	COG0471	metal ion transport
AVS47_RS01955	COG1309	transcriptional regulator
AVS47_RS01965	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AVS47_RS01980	COG2823	Periplasmic or secreted lipoprotein
AVS47_RS01985	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AVS47_RS02000	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AVS47_RS02020	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AVS47_RS02030	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AVS47_RS02050	COG0492	ferredoxin-NADP+ reductase activity
AVS47_RS02060	COG3181	Tripartite tricarboxylate transporter family receptor
AVS47_RS02065	COG1024	Enoyl-CoA hydratase
AVS47_RS02065	COG1250	3-hydroxyacyl-CoA dehydrogenase
AVS47_RS02070	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AVS47_RS02075	COG0028	Belongs to the TPP enzyme family
AVS47_RS02100	COG3181	Tripartite tricarboxylate transporter family receptor
AVS47_RS02110	COG0697	spore germination
AVS47_RS02140	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AVS47_RS02145	COG0463	Glycosyl transferase, family 2
AVS47_RS02165	COG0786	glutamate:sodium symporter activity
AVS47_RS02175	COG2031	fatty acid transporter
AVS47_RS02190	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AVS47_RS02195	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AVS47_RS02220	COG3181	Tripartite tricarboxylate transporter family receptor
AVS47_RS02230	COG0277	FAD linked oxidase domain protein
AVS47_RS02235	COG1960	acyl-CoA dehydrogenase activity
AVS47_RS02240	COG1960	acyl-CoA dehydrogenase activity
AVS47_RS02250	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AVS47_RS02265	COG2072	flavoprotein involved in K transport
AVS47_RS02270	COG0604	alcohol dehydrogenase
AVS47_RS02285	COG1024	Enoyl-CoA hydratase
AVS47_RS02305	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AVS47_RS02310	COG1522	sequence-specific DNA binding
AVS47_RS02315	COG0183	Belongs to the thiolase family
AVS47_RS02325	COG1960	acyl-CoA dehydrogenase activity
AVS47_RS02365	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AVS47_RS02370	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AVS47_RS02375	COG2890	protein-(glutamine-N5) methyltransferase activity
AVS47_RS02380	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AVS47_RS02390	COG3181	Tripartite tricarboxylate transporter family receptor
AVS47_RS02425	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AVS47_RS02430	COG1660	Displays ATPase and GTPase activities
AVS47_RS02440	COG2010	Cytochrome c
AVS47_RS02440	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AVS47_RS02445	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AVS47_RS02455	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AVS47_RS02460	COG1137	ATPase activity
AVS47_RS02475	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AVS47_RS02485	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AVS47_RS02520	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AVS47_RS02525	COG3568	Endonuclease Exonuclease Phosphatase
AVS47_RS02530	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AVS47_RS02560	COG0154	amidase activity
AVS47_RS02570	COG1414	Transcriptional regulator
AVS47_RS02580	COG1024	Enoyl-CoA hydratase
AVS47_RS02580	COG1250	3-hydroxyacyl-CoA dehydrogenase
AVS47_RS02590	COG2132	Multicopper oxidase
AVS47_RS02620	COG1250	3-hydroxyacyl-CoA dehydrogenase
AVS47_RS02645	COG1024	Enoyl-CoA hydratase
AVS47_RS02650	COG1024	Enoyl-CoA hydratase
AVS47_RS02655	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AVS47_RS02675	COG0601	transmembrane transport
AVS47_RS02680	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVS47_RS02685	COG4172	Belongs to the ABC transporter superfamily
AVS47_RS02695	COG2195	Cleaves the N-terminal amino acid of tripeptides
AVS47_RS02705	COG0210	DNA helicase
AVS47_RS02710	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AVS47_RS02715	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AVS47_RS02725	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AVS47_RS02730	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AVS47_RS02735	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AVS47_RS02740	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AVS47_RS02745	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AVS47_RS02750	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AVS47_RS02760	COG0356	it plays a direct role in the translocation of protons across the membrane
AVS47_RS02785	COG1024	Enoyl-CoA hydratase
AVS47_RS02790	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AVS47_RS02795	COG3634	alkyl hydroperoxide reductase activity
AVS47_RS02805	COG0037	tRNA processing
AVS47_RS02815	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AVS47_RS02820	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AVS47_RS02825	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AVS47_RS02830	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AVS47_RS02835	COG2967	ApaG domain
AVS47_RS02840	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AVS47_RS02845	COG0546	phosphoglycolate phosphatase activity
AVS47_RS02855	COG0512	Glutamine amidotransferase of anthranilate synthase
AVS47_RS02860	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AVS47_RS02865	COG0134	indole-3-glycerol-phosphate synthase activity
AVS47_RS02890	COG1960	acyl-CoA dehydrogenase activity
AVS47_RS02895	COG0583	DNA-binding transcription factor activity
AVS47_RS02910	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AVS47_RS02915	COG0259	pyridoxamine-phosphate oxidase activity
AVS47_RS02925	COG2814	Major facilitator Superfamily
AVS47_RS02930	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AVS47_RS02935	COG2188	Transcriptional regulator
AVS47_RS02940	COG0318	PFAM AMP-dependent synthetase and ligase
AVS47_RS02960	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AVS47_RS02970	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AVS47_RS02985	COG1215	transferase activity, transferring glycosyl groups
AVS47_RS02995	COG0601	transmembrane transport
AVS47_RS03010	COG0488	(ABC) transporter
AVS47_RS03030	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AVS47_RS03035	COG2894	cell division
AVS47_RS03040	COG0850	regulation of cytokinetic process
AVS47_RS03045	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AVS47_RS03060	COG1271	oxidase subunit
AVS47_RS03095	COG2979	Protein of unknown function (DUF533)
AVS47_RS03115	COG1388	LysM domain
AVS47_RS03115	COG0741	lytic transglycosylase activity
AVS47_RS03120	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AVS47_RS03125	COG2226	methyltransferase
AVS47_RS03130	COG0328	RNA-DNA hybrid ribonuclease activity
AVS47_RS03180	COG2030	dehydratase
AVS47_RS03185	COG0183	Belongs to the thiolase family
AVS47_RS03230	COG1960	acyl-CoA dehydrogenase activity
AVS47_RS03245	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AVS47_RS03250	COG1028	Short-chain dehydrogenase reductase Sdr
AVS47_RS03265	COG2718	Belongs to the UPF0229 family
AVS47_RS03270	COG2719	SpoVR family
AVS47_RS03295	COG2188	Transcriptional regulator
AVS47_RS03310	COG0633	Ferredoxin
AVS47_RS03320	COG0829	nickel cation binding
AVS47_RS03325	COG0831	urea catabolic process
AVS47_RS03335	COG0832	Belongs to the urease beta subunit family
AVS47_RS03340	COG0804	urea catabolic process
AVS47_RS03350	COG0830	nickel cation binding
AVS47_RS03355	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AVS47_RS03375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVS47_RS03380	COG0601	transmembrane transport
AVS47_RS03385	COG0747	negative chemotaxis
AVS47_RS03395	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AVS47_RS03400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AVS47_RS03410	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AVS47_RS03420	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
AVS47_RS03425	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AVS47_RS03430	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AVS47_RS03445	COG0438	transferase activity, transferring glycosyl groups
AVS47_RS03460	COG0438	transferase activity, transferring glycosyl groups
AVS47_RS03465	COG0438	transferase activity, transferring glycosyl groups
AVS47_RS03470	COG0166	Belongs to the GPI family
AVS47_RS03485	COG0277	FAD linked oxidase domain protein
AVS47_RS03490	COG0745	RESPONSE REGULATOR receiver
AVS47_RS03495	COG0642	Histidine kinase
AVS47_RS03500	COG1368	sulfuric ester hydrolase activity
AVS47_RS03510	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AVS47_RS03535	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AVS47_RS03545	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AVS47_RS03550	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AVS47_RS03560	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AVS47_RS03565	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AVS47_RS03570	COG0193	aminoacyl-tRNA hydrolase activity
AVS47_RS03580	COG0012	GTP binding
AVS47_RS03585	COG0582	viral genome integration into host DNA
AVS47_RS03610	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AVS47_RS03660	COG3181	Tripartite tricarboxylate transporter family receptor
AVS47_RS03670	COG0745	RESPONSE REGULATOR receiver
AVS47_RS03695	COG1309	transcriptional regulator
AVS47_RS03725	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AVS47_RS03735	COG0405	Gamma-glutamyltransferase
AVS47_RS03750	COG1280	lysine exporter protein (LysE YggA)
AVS47_RS03810	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AVS47_RS03815	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AVS47_RS03825	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AVS47_RS03830	COG0513	Belongs to the DEAD box helicase family
AVS47_RS03840	COG0617	tRNA 3'-terminal CCA addition
AVS47_RS03855	COG0477	Major facilitator Superfamily
AVS47_RS03865	COG0583	DNA-binding transcription factor activity
AVS47_RS03880	COG1950	PFAM Membrane protein of
AVS47_RS03885	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AVS47_RS03900	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AVS47_RS03910	COG1560	Kdo2-lipid A biosynthetic process
AVS47_RS03915	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AVS47_RS03925	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AVS47_RS03935	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
AVS47_RS03945	COG0803	Belongs to the bacterial solute-binding protein 9 family
AVS47_RS03965	COG0735	belongs to the Fur family
AVS47_RS03970	COG0523	cobalamin synthesis protein
AVS47_RS03980	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AVS47_RS03985	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AVS47_RS03995	COG2096	Adenosyltransferase
AVS47_RS04005	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AVS47_RS04010	COG2084	Dehydrogenase
AVS47_RS04060	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AVS47_RS04065	COG0129	dihydroxy-acid dehydratase activity
AVS47_RS04070	COG4654	Cytochrome c, class I
AVS47_RS04075	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AVS47_RS04125	COG1473	amidohydrolase
AVS47_RS04130	COG0418	dihydroorotase activity
AVS47_RS04135	COG0488	(ABC) transporter
AVS47_RS04145	COG2001	Belongs to the MraZ family
AVS47_RS04150	COG0275	rRNA processing
AVS47_RS04155	COG3116	cell division
AVS47_RS04165	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AVS47_RS04170	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AVS47_RS04175	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AVS47_RS04185	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AVS47_RS04190	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AVS47_RS04195	COG1181	Belongs to the D-alanine--D-alanine ligase family
AVS47_RS04200	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AVS47_RS04210	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AVS47_RS04215	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AVS47_RS04225	COG0739	heme binding
AVS47_RS04230	COG0653	protein targeting
AVS47_RS04250	COG1028	Short-chain dehydrogenase reductase Sdr
AVS47_RS04255	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AVS47_RS04260	COG1522	sequence-specific DNA binding
AVS47_RS04280	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AVS47_RS04290	COG0557	exoribonuclease II activity
AVS47_RS04295	COG3150	esterase
AVS47_RS04300	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AVS47_RS04305	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AVS47_RS04310	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AVS47_RS04315	COG0511	ligase activity, forming carbon-carbon bonds
AVS47_RS04320	COG0439	Biotin carboxylase
AVS47_RS04325	COG2264	protein methyltransferase activity
AVS47_RS04335	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AVS47_RS04360	COG1696	Membrane protein involved in D-alanine export
AVS47_RS04365	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AVS47_RS04400	COG1522	sequence-specific DNA binding
AVS47_RS04415	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AVS47_RS04420	COG1042	CoA-binding domain protein
AVS47_RS04420	COG0045	succinate-CoA ligase (ADP-forming) activity
AVS47_RS04420	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AVS47_RS04435	COG1802	Transcriptional regulator
AVS47_RS04440	COG3069	C4-dicarboxylate transmembrane transporter activity
AVS47_RS04445	COG0513	Belongs to the DEAD box helicase family
AVS47_RS04450	COG0346	lactoylglutathione lyase activity
AVS47_RS04455	COG1335	isochorismatase
AVS47_RS04460	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AVS47_RS04465	COG1116	anion transmembrane transporter activity
AVS47_RS04480	COG3028	Belongs to the UPF0307 family
AVS47_RS04485	COG0312	modulator of DNA gyrase
AVS47_RS04490	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AVS47_RS04495	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AVS47_RS04500	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AVS47_RS04505	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AVS47_RS04515	COG0316	Belongs to the HesB IscA family
AVS47_RS04520	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AVS47_RS04535	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AVS47_RS04545	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AVS47_RS04550	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AVS47_RS04565	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AVS47_RS04565	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AVS47_RS04595	COG0583	DNA-binding transcription factor activity
AVS47_RS04600	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AVS47_RS04635	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
AVS47_RS04645	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AVS47_RS04650	COG1845	cytochrome c oxidase, subunit III
AVS47_RS04655	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AVS47_RS04660	COG0640	Transcriptional regulator
AVS47_RS04680	COG3220	belongs to the UPF0276 family
AVS47_RS04725	COG1666	GTP binding
AVS47_RS04760	COG0312	modulator of DNA gyrase
AVS47_RS04765	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AVS47_RS04770	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
AVS47_RS04770	COG3210	domain, Protein
AVS47_RS04770	COG3064	Membrane
AVS47_RS04770	COG3064	Membrane
AVS47_RS04770	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
AVS47_RS04770	COG3210	domain, Protein
AVS47_RS04775	COG0277	FAD linked oxidase domain protein
AVS47_RS04780	COG0277	FAD linked oxidase domain protein
AVS47_RS04785	COG0277	FAD linked oxidase domain protein
AVS47_RS04790	COG0247	lactate metabolic process
AVS47_RS04795	COG2819	hydrolase of the alpha beta superfamily
AVS47_RS04820	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AVS47_RS04840	COG0583	DNA-binding transcription factor activity
AVS47_RS04845	COG0482	sulfurtransferase activity
AVS47_RS04850	COG0730	response to heat
AVS47_RS04855	COG0625	glutathione transferase activity
AVS47_RS04860	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AVS47_RS04865	COG3909	cytochrome
AVS47_RS04905	COG0154	amidase activity
AVS47_RS04910	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AVS47_RS04915	COG1024	Enoyl-CoA hydratase
AVS47_RS04930	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AVS47_RS04945	COG1028	Short-chain dehydrogenase reductase Sdr
AVS47_RS04950	COG1414	Transcriptional regulator
AVS47_RS04960	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AVS47_RS04965	COG0251	oxidation-reduction process
AVS47_RS04970	COG0559	Belongs to the binding-protein-dependent transport system permease family
AVS47_RS04990	COG1902	pentaerythritol trinitrate reductase activity
AVS47_RS05005	COG0583	DNA-binding transcription factor activity
AVS47_RS05015	COG0590	tRNA wobble adenosine to inosine editing
AVS47_RS05020	COG2807	transmembrane transport
AVS47_RS05040	COG0154	amidase activity
AVS47_RS05045	COG0307	riboflavin synthase, alpha
AVS47_RS05050	COG3181	Tripartite tricarboxylate transporter family receptor
AVS47_RS05055	COG1522	sequence-specific DNA binding
AVS47_RS05065	COG0318	PFAM AMP-dependent synthetase and ligase
AVS47_RS05075	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AVS47_RS05095	COG1063	alcohol dehydrogenase
AVS47_RS05120	COG1418	mRNA catabolic process
AVS47_RS05125	COG1448	Aminotransferase
AVS47_RS05130	COG0583	DNA-binding transcription factor activity
AVS47_RS05140	COG0477	Major facilitator Superfamily
AVS47_RS05145	COG1028	Short-chain dehydrogenase reductase Sdr
AVS47_RS05160	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AVS47_RS05165	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AVS47_RS05170	COG0583	DNA-binding transcription factor activity
AVS47_RS05230	COG1028	Short-chain dehydrogenase reductase Sdr
AVS47_RS05235	COG1309	transcriptional regulator
AVS47_RS05245	COG2982	Protein involved in outer membrane biogenesis
AVS47_RS05250	COG2818	Glycosylase
AVS47_RS05270	COG1653	transport
AVS47_RS05280	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AVS47_RS05285	COG3842	ATPase activity
AVS47_RS05290	COG0395	ABC-type sugar transport system, permease component
AVS47_RS05295	COG1175	transmembrane transport
AVS47_RS05315	COG3181	Tripartite tricarboxylate transporter family receptor
AVS47_RS05320	COG2186	Transcriptional regulator
AVS47_RS05350	COG1454	alcohol dehydrogenase
AVS47_RS05370	COG2011	ABC-type metal ion transport system permease component
AVS47_RS05375	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AVS47_RS05380	COG1501	Belongs to the glycosyl hydrolase 31 family
AVS47_RS05405	COG0318	PFAM AMP-dependent synthetase and ligase
AVS47_RS05410	COG1473	amidohydrolase
AVS47_RS05420	COG2855	membrane
AVS47_RS05430	COG2239	Acts as a magnesium transporter
AVS47_RS05450	COG3181	Tripartite tricarboxylate transporter family receptor
AVS47_RS05460	COG1722	exodeoxyribonuclease VII activity
AVS47_RS05465	COG0142	geranyltranstransferase activity
AVS47_RS05470	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AVS47_RS05475	COG1469	GTP cyclohydrolase I activity
AVS47_RS05480	COG0360	Binds together with S18 to 16S ribosomal RNA
AVS47_RS05485	COG2965	DNA replication, synthesis of RNA primer
AVS47_RS05490	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AVS47_RS05495	COG0359	binds to the 23S rRNA
AVS47_RS05505	COG0305	Participates in initiation and elongation during chromosome replication
AVS47_RS05515	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AVS47_RS05520	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AVS47_RS05525	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AVS47_RS05530	COG3737	Protein of unknown function (DUF498/DUF598)
AVS47_RS05535	COG0436	Aminotransferase
AVS47_RS05560	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AVS47_RS05590	COG0268	Binds directly to 16S ribosomal RNA
AVS47_RS05600	COG0728	peptidoglycan biosynthetic process
AVS47_RS05610	COG0563	adenylate kinase activity
AVS47_RS05615	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AVS47_RS05620	COG2835	tetraacyldisaccharide 4'-kinase activity
AVS47_RS05625	COG1663	tetraacyldisaccharide 4'-kinase activity
AVS47_RS05630	COG0848	biopolymer transport protein
AVS47_RS05635	COG0811	peptide transport
AVS47_RS05645	COG1570	exodeoxyribonuclease VII activity
AVS47_RS05650	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AVS47_RS05655	COG0038	chloride channel
AVS47_RS05660	COG0183	Belongs to the thiolase family
AVS47_RS05670	COG1278	Cold shock
AVS47_RS05675	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AVS47_RS05685	COG4953	penicillin-binding protein 1C
AVS47_RS05690	COG0542	response to heat
AVS47_RS05695	COG2995	paraquat-inducible protein a
AVS47_RS05700	COG3008	intermembrane lipid transfer
AVS47_RS05700	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AVS47_RS05710	COG0506	proline dehydrogenase activity
AVS47_RS05710	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AVS47_RS05710	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AVS47_RS05745	COG2271	Major facilitator Superfamily
AVS47_RS05750	COG1309	transcriptional regulator
AVS47_RS05760	COG3468	outer membrane autotransporter barrel domain protein
AVS47_RS05790	COG0477	Major facilitator Superfamily
AVS47_RS05800	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AVS47_RS05805	COG1845	cytochrome c oxidase, subunit III
AVS47_RS05810	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AVS47_RS05820	COG1028	Short-chain dehydrogenase reductase Sdr
AVS47_RS05840	COG0789	Transcriptional regulator
AVS47_RS05865	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AVS47_RS05870	COG0697	spore germination
AVS47_RS05880	COG0678	peroxiredoxin activity
AVS47_RS05890	COG0412	Dienelactone hydrolase
AVS47_RS05900	COG0315	cyclic pyranopterin monophosphate synthase activity
AVS47_RS05915	COG0521	Mo-molybdopterin cofactor biosynthetic process
AVS47_RS05920	COG0303	'Molybdopterin
AVS47_RS05925	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AVS47_RS05945	COG0165	Argininosuccinate lyase
AVS47_RS05950	COG0668	transmembrane transport
AVS47_RS05995	COG0747	negative chemotaxis
AVS47_RS06000	COG0601	transmembrane transport
AVS47_RS06005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVS47_RS06010	COG1162	GTPase activity
AVS47_RS06015	COG0501	Belongs to the peptidase M48B family
AVS47_RS06020	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AVS47_RS06030	COG3327	negative regulation of DNA-templated transcription, initiation
AVS47_RS06035	COG3396	Phenylacetate-CoA oxygenase
AVS47_RS06040	COG3460	Phenylacetate-CoA oxygenase
AVS47_RS06045	COG3396	Phenylacetate-CoA oxygenase
AVS47_RS06050	COG2151	metal-sulfur cluster biosynthetic enzyme
AVS47_RS06055	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AVS47_RS06065	COG1012	belongs to the aldehyde dehydrogenase family
AVS47_RS06070	COG1024	Enoyl-CoA hydratase
AVS47_RS06075	COG2050	protein possibly involved in aromatic compounds catabolism
AVS47_RS06085	COG3539	Fimbrial protein
AVS47_RS06105	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AVS47_RS06110	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AVS47_RS06110	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AVS47_RS06115	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AVS47_RS06120	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AVS47_RS06120	COG0047	phosphoribosylformylglycinamidine synthase activity
AVS47_RS06125	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
AVS47_RS06125	COG3210	domain, Protein
AVS47_RS06125	COG3064	Membrane
AVS47_RS06150	COG0235	Class ii aldolase
AVS47_RS06155	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AVS47_RS06160	COG0720	synthase
AVS47_RS06165	COG0602	queuosine metabolic process
AVS47_RS06190	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AVS47_RS06225	COG3181	Tripartite tricarboxylate transporter family receptor
AVS47_RS06255	COG3842	ATPase activity
AVS47_RS06265	COG0395	ABC-type sugar transport system, permease component
AVS47_RS06295	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AVS47_RS06300	COG0420	3'-5' exonuclease activity
AVS47_RS06345	COG0519	Catalyzes the synthesis of GMP from XMP
AVS47_RS06345	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AVS47_RS06360	COG3550	peptidyl-serine autophosphorylation
AVS47_RS06370	COG0477	Major facilitator Superfamily
AVS47_RS06385	COG1228	amidohydrolase
AVS47_RS06395	COG1116	anion transmembrane transporter activity
AVS47_RS06400	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AVS47_RS06440	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AVS47_RS06455	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AVS47_RS06485	COG2814	Major facilitator Superfamily
AVS47_RS06500	COG1280	lysine exporter protein (LysE YggA)
AVS47_RS06515	COG0747	negative chemotaxis
AVS47_RS06520	COG0601	transmembrane transport
AVS47_RS06525	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVS47_RS06530	COG4172	Belongs to the ABC transporter superfamily
AVS47_RS06535	COG1609	Transcriptional regulator
AVS47_RS06565	COG0586	Pfam SNARE associated Golgi protein
AVS47_RS06580	COG0500	methyltransferase
AVS47_RS06595	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AVS47_RS06605	COG0756	dUTP diphosphatase activity
AVS47_RS06620	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AVS47_RS06625	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AVS47_RS06630	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AVS47_RS06635	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AVS47_RS06635	COG0072	phenylalanine-tRNA ligase activity
AVS47_RS06640	COG0776	regulation of translation
AVS47_RS06710	COG0540	Belongs to the ATCase OTCase family
AVS47_RS06715	COG2974	May be involved in recombination
AVS47_RS06725	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AVS47_RS06730	COG0583	DNA-binding transcription factor activity
AVS47_RS06750	COG1028	Short-chain dehydrogenase reductase Sdr
AVS47_RS06765	COG3842	ATPase activity
AVS47_RS06770	COG1024	Enoyl-CoA hydratase
AVS47_RS06770	COG1250	3-hydroxyacyl-CoA dehydrogenase
AVS47_RS06790	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AVS47_RS06795	COG2137	regulation of response to DNA damage stimulus
AVS47_RS06805	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AVS47_RS06815	COG0045	succinate-CoA ligase (ADP-forming) activity
AVS47_RS06820	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AVS47_RS06825	COG0861	Integral membrane protein TerC family
AVS47_RS06830	COG0861	Integral membrane protein TerC family
AVS47_RS06835	COG0181	hydroxymethylbilane synthase activity
AVS47_RS06895	COG4964	Belongs to the GSP D family
AVS47_RS06930	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AVS47_RS06940	COG0583	DNA-binding transcription factor activity
AVS47_RS06950	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AVS47_RS06955	COG4311	Sarcosine oxidase, delta subunit
AVS47_RS06960	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AVS47_RS06960	COG0446	pyridine nucleotide-disulphide oxidoreductase
AVS47_RS06995	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AVS47_RS07000	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AVS47_RS07005	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AVS47_RS07010	COG0735	belongs to the Fur family
AVS47_RS07015	COG0497	DNA recombination
AVS47_RS07020	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AVS47_RS07025	COG1420	regulation of RNA biosynthetic process
AVS47_RS07030	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AVS47_RS07040	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AVS47_RS07050	COG0443	Heat shock 70 kDa protein
AVS47_RS07060	COG0612	Peptidase, M16
AVS47_RS07080	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AVS47_RS07125	COG0745	RESPONSE REGULATOR receiver
AVS47_RS07135	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AVS47_RS07140	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AVS47_RS07145	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AVS47_RS07160	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AVS47_RS07180	COG1193	negative regulation of DNA recombination
AVS47_RS07185	COG0492	ferredoxin-NADP+ reductase activity
AVS47_RS07190	COG1674	ftsk spoiiie
AVS47_RS07195	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AVS47_RS07200	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AVS47_RS07205	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AVS47_RS07230	COG3706	GGDEF domain
AVS47_RS07250	COG2814	Major facilitator Superfamily
AVS47_RS07280	COG3486	L-lysine 6-monooxygenase (NADPH) activity
AVS47_RS07295	COG1028	Short-chain dehydrogenase reductase Sdr
AVS47_RS07305	COG3022	response to hydroperoxide
AVS47_RS07335	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AVS47_RS07345	COG2197	response regulator
AVS47_RS07350	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AVS47_RS07355	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AVS47_RS07360	COG0189	ligase activity
AVS47_RS07370	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AVS47_RS07375	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AVS47_RS07385	COG1764	response to oxidative stress
AVS47_RS07390	COG2423	ornithine cyclodeaminase activity
AVS47_RS07400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVS47_RS07405	COG0765	amino acid transport
AVS47_RS07410	COG0765	amino acid transport
AVS47_RS07415	COG1126	abc transporter atp-binding protein
AVS47_RS07470	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AVS47_RS07480	COG2944	sequence-specific DNA binding
AVS47_RS07490	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AVS47_RS07495	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AVS47_RS07500	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AVS47_RS07505	COG0009	L-threonylcarbamoyladenylate synthase
AVS47_RS07510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVS47_RS07515	COG1414	Transcriptional regulator
AVS47_RS07530	COG0765	amino acid transport
AVS47_RS07535	COG1126	abc transporter atp-binding protein
AVS47_RS07540	COG0028	Belongs to the TPP enzyme family
AVS47_RS07555	COG0028	Belongs to the TPP enzyme family
AVS47_RS07560	COG0583	DNA-binding transcription factor activity
AVS47_RS07565	COG4974	Belongs to the 'phage' integrase family
AVS47_RS07570	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AVS47_RS07575	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
AVS47_RS07590	COG1686	Belongs to the peptidase S11 family
AVS47_RS07600	COG2814	Major facilitator Superfamily
AVS47_RS07610	COG1074	ATP-dependent DNA helicase activity
AVS47_RS07625	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AVS47_RS07630	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AVS47_RS07635	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AVS47_RS07655	COG2321	neutral zinc metallopeptidase
AVS47_RS07660	COG0009	L-threonylcarbamoyladenylate synthase
AVS47_RS07705	COG3360	Dodecin
AVS47_RS07710	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AVS47_RS07715	COG2850	peptidyl-arginine hydroxylation
AVS47_RS07720	COG3539	Fimbrial protein
AVS47_RS07725	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AVS47_RS07730	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AVS47_RS07750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVS47_RS07755	COG0765	amino acid transport
AVS47_RS07760	COG1126	abc transporter atp-binding protein
AVS47_RS07765	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AVS47_RS07770	COG1758	RNA polymerase activity
AVS47_RS07775	COG0194	GDP metabolic process
AVS47_RS07780	COG3258	Cytochrome c
AVS47_RS07785	COG2863	cytochrome
AVS47_RS07790	COG1028	Short-chain dehydrogenase reductase Sdr
AVS47_RS07795	COG0791	NLP P60 protein
AVS47_RS07800	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AVS47_RS07820	COG1561	YicC-like family, N-terminal region
AVS47_RS07825	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AVS47_RS07840	COG0840	transmembrane signaling receptor activity
AVS47_RS07845	COG2199	diguanylate cyclase activity
AVS47_RS07845	COG2200	EAL domain
AVS47_RS07850	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AVS47_RS07860	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AVS47_RS07865	COG0174	glutamine synthetase
AVS47_RS07875	COG2204	response regulator
AVS47_RS07880	COG0583	DNA-binding transcription factor activity
AVS47_RS07885	COG1741	Belongs to the pirin family
AVS47_RS07890	COG1741	Belongs to the pirin family
AVS47_RS07900	COG3842	ATPase activity
AVS47_RS07905	COG1178	ABC-type Fe3 transport system permease component
AVS47_RS07910	COG1840	ABC-type Fe3 transport system, periplasmic component
AVS47_RS07920	COG0583	DNA-binding transcription factor activity
AVS47_RS07930	COG0656	L-ascorbic acid biosynthetic process
AVS47_RS07945	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AVS47_RS07950	COG0583	DNA-binding transcription factor activity
AVS47_RS07965	COG0783	Belongs to the Dps family
AVS47_RS07985	COG0463	Glycosyl transferase, family 2
AVS47_RS08005	COG0438	transferase activity, transferring glycosyl groups
AVS47_RS08020	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AVS47_RS08045	COG0300	oxidoreductase activity
AVS47_RS08090	COG0861	Integral membrane protein TerC family
AVS47_RS08095	COG1028	Short-chain dehydrogenase reductase Sdr
AVS47_RS08115	COG0714	Associated with various cellular activities
AVS47_RS08150	COG3119	arylsulfatase activity
AVS47_RS08175	COG2197	response regulator
AVS47_RS08185	COG2944	sequence-specific DNA binding
AVS47_RS08190	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
AVS47_RS08195	COG0625	glutathione transferase activity
AVS47_RS08225	COG0179	Fumarylacetoacetate (FAA) hydrolase
AVS47_RS08230	COG1028	Short-chain dehydrogenase reductase Sdr
AVS47_RS08275	COG0431	NADPH-dependent FMN reductase
AVS47_RS08305	COG1028	Short-chain dehydrogenase reductase Sdr
AVS47_RS08310	COG0583	DNA-binding transcription factor activity
AVS47_RS08325	COG3181	Tripartite tricarboxylate transporter family receptor
AVS47_RS08330	COG2111	Na H antiporter
AVS47_RS08330	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AVS47_RS08335	COG1006	Multisubunit Na H antiporter MnhC subunit
AVS47_RS08340	COG0651	ATP synthesis coupled electron transport
AVS47_RS08345	COG1863	multisubunit Na H antiporter MnhE subunit
AVS47_RS08350	COG2212	antiporter activity
AVS47_RS08375	COG0590	tRNA wobble adenosine to inosine editing
AVS47_RS08380	COG1619	proteins homologs of microcin C7 resistance protein MccF
AVS47_RS08385	COG1024	Enoyl-CoA hydratase
AVS47_RS08400	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AVS47_RS08405	COG0488	(ABC) transporter
AVS47_RS08440	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AVS47_RS08440	COG1017	nitric oxide dioxygenase activity
AVS47_RS08445	COG1959	2 iron, 2 sulfur cluster binding
AVS47_RS08450	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AVS47_RS08470	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AVS47_RS08475	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AVS47_RS08480	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AVS47_RS08485	COG0084	hydrolase, TatD family'
AVS47_RS08500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVS47_RS08510	COG1126	abc transporter atp-binding protein
AVS47_RS08515	COG0010	Belongs to the arginase family
AVS47_RS08520	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AVS47_RS08525	COG1012	belongs to the aldehyde dehydrogenase family
AVS47_RS08535	COG0028	Belongs to the TPP enzyme family
AVS47_RS08545	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AVS47_RS08545	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AVS47_RS08555	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AVS47_RS08570	COG3189	MarR family transcriptional regulator
AVS47_RS08575	COG2010	Cytochrome c
AVS47_RS08600	COG4336	lyase activity
AVS47_RS08610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVS47_RS08610	COG2205	protein histidine kinase activity
AVS47_RS08615	COG2197	response regulator
AVS47_RS08620	COG3064	Membrane
AVS47_RS08620	COG3210	domain, Protein
AVS47_RS08620	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
AVS47_RS08630	COG3121	Chaperone
AVS47_RS08635	COG3188	usher protein
AVS47_RS08640	COG3539	Fimbrial protein
AVS47_RS08645	COG2831	hemolysin activation secretion protein
AVS47_RS08660	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AVS47_RS08685	COG0583	DNA-binding transcription factor activity
AVS47_RS08710	COG0668	transmembrane transport
AVS47_RS08730	COG0483	inositol monophosphate 1-phosphatase activity
AVS47_RS08735	COG1253	flavin adenine dinucleotide binding
AVS47_RS08740	COG1968	undecaprenyl-diphosphatase activity
AVS47_RS08745	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AVS47_RS08760	COG0215	cysteine-tRNA ligase activity
AVS47_RS08770	COG0825	malonyl-CoA metabolic process
AVS47_RS08780	COG0037	tRNA processing
AVS47_RS08785	COG0527	aspartate kinase activity
AVS47_RS08810	COG1250	3-hydroxyacyl-CoA dehydrogenase
AVS47_RS08815	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AVS47_RS08815	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AVS47_RS08830	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AVS47_RS08835	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
AVS47_RS08840	COG1028	Short-chain dehydrogenase reductase Sdr
AVS47_RS08850	COG0583	DNA-binding transcription factor activity
AVS47_RS08880	COG3842	ATPase activity
AVS47_RS08890	COG0446	pyridine nucleotide-disulphide oxidoreductase
AVS47_RS08890	COG1902	pentaerythritol trinitrate reductase activity
AVS47_RS08895	COG1414	Transcriptional regulator
AVS47_RS08900	COG1832	CoA-binding protein
AVS47_RS08910	COG0251	oxidation-reduction process
AVS47_RS08935	COG1902	pentaerythritol trinitrate reductase activity
AVS47_RS08945	COG1215	transferase activity, transferring glycosyl groups
AVS47_RS08950	COG1649	PFAM Uncharacterised BCR, COG1649
AVS47_RS08950	COG0726	polysaccharide deacetylase
AVS47_RS08970	COG1846	Transcriptional regulator
AVS47_RS08975	COG2197	response regulator
AVS47_RS08990	COG0166	Belongs to the GPI family
AVS47_RS08995	COG1045	serine acetyltransferase
AVS47_RS09005	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AVS47_RS09010	COG0483	inositol monophosphate 1-phosphatase activity
AVS47_RS09015	COG1012	belongs to the aldehyde dehydrogenase family
AVS47_RS09020	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AVS47_RS09035	COG0210	DNA helicase
AVS47_RS09040	COG0598	Magnesium transport protein CorA
AVS47_RS09050	COG0747	negative chemotaxis
AVS47_RS09055	COG0601	transmembrane transport
AVS47_RS09060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVS47_RS09065	COG4172	Belongs to the ABC transporter superfamily
AVS47_RS09070	COG1846	Transcriptional regulator
AVS47_RS09120	COG4964	Belongs to the GSP D family
AVS47_RS09160	COG2204	response regulator
AVS47_RS09175	COG1595	DNA-templated transcription, initiation
AVS47_RS09185	COG3474	cytochrome
AVS47_RS09190	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AVS47_RS09205	COG3384	dioxygenase
AVS47_RS09210	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AVS47_RS09235	COG2885	chlorophyll binding
AVS47_RS09270	COG0697	spore germination
AVS47_RS09275	COG0730	response to heat
AVS47_RS09295	COG0583	DNA-binding transcription factor activity
AVS47_RS09300	COG0427	acetyl-CoA hydrolase
AVS47_RS09355	COG1250	3-hydroxyacyl-CoA dehydrogenase
AVS47_RS09360	COG0154	amidase activity
AVS47_RS09370	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AVS47_RS09385	COG0495	leucyl-tRNA aminoacylation
AVS47_RS09390	COG2814	Major facilitator Superfamily
AVS47_RS09415	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AVS47_RS09420	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AVS47_RS09425	COG2814	Major facilitator Superfamily
AVS47_RS09430	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AVS47_RS09445	COG4176	ABC-type proline glycine betaine transport system permease component
AVS47_RS09455	COG1942	4-Oxalocrotonate Tautomerase
AVS47_RS09460	COG0183	Belongs to the thiolase family
AVS47_RS09470	COG1802	Transcriptional regulator
AVS47_RS09480	COG1024	Enoyl-CoA hydratase
AVS47_RS09485	COG0318	PFAM AMP-dependent synthetase and ligase
AVS47_RS09490	COG0318	PFAM AMP-dependent synthetase and ligase
AVS47_RS09500	COG2032	superoxide dismutase activity
AVS47_RS09515	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AVS47_RS09540	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AVS47_RS09545	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AVS47_RS09555	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AVS47_RS09560	COG0736	holo-[acyl-carrier-protein] synthase activity
AVS47_RS09565	COG1472	Belongs to the glycosyl hydrolase 3 family
AVS47_RS09570	COG0322	excinuclease ABC activity
AVS47_RS09575	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AVS47_RS09590	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AVS47_RS09590	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AVS47_RS09595	COG2224	Isocitrate lyase
AVS47_RS09615	COG0559	Belongs to the binding-protein-dependent transport system permease family
AVS47_RS09625	COG4638	Rieske (2fe-2S)
AVS47_RS09635	COG1024	Enoyl-CoA hydratase
AVS47_RS09645	COG0633	Ferredoxin
AVS47_RS09650	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AVS47_RS09665	COG0183	Belongs to the thiolase family
AVS47_RS09710	COG2346	COG2346, Truncated hemoglobins
AVS47_RS09840	COG2207	Transcriptional regulator
AVS47_RS09885	COG1132	(ABC) transporter
AVS47_RS09910	COG0659	secondary active sulfate transmembrane transporter activity
AVS47_RS09940	COG2169	Transcriptional regulator
AVS47_RS09945	COG5507	3-demethylubiquinone-9 3-methyltransferase
AVS47_RS09950	COG0384	phenazine biosynthesis protein PhzF
AVS47_RS09955	COG0583	DNA-binding transcription factor activity
AVS47_RS09960	COG2733	membrane
AVS47_RS09975	COG1012	belongs to the aldehyde dehydrogenase family
AVS47_RS09980	COG3284	Transcriptional regulator
AVS47_RS10000	COG1380	Effector of murein hydrolase LrgA
AVS47_RS10005	COG4106	trans-aconitate 2-methyltransferase activity
AVS47_RS10005	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AVS47_RS10015	COG0156	8-amino-7-oxononanoate synthase activity
AVS47_RS10085	COG1131	(ABC) transporter
AVS47_RS10090	COG0842	Transport permease protein
AVS47_RS10095	COG0628	permease
AVS47_RS10130	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AVS47_RS10140	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AVS47_RS10145	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AVS47_RS10150	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AVS47_RS10155	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AVS47_RS10160	COG0330	HflC and HflK could
AVS47_RS10165	COG0330	HflC and HflK could
AVS47_RS10170	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AVS47_RS10175	COG1923	regulation of RNA biosynthetic process
AVS47_RS10180	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AVS47_RS10185	COG1160	GTP binding
AVS47_RS10190	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AVS47_RS10195	COG2976	Protein conserved in bacteria
AVS47_RS10200	COG0124	histidyl-tRNA synthetase
AVS47_RS10205	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AVS47_RS10215	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AVS47_RS10220	COG0105	UTP biosynthetic process
AVS47_RS10225	COG0525	valine-tRNA ligase activity
AVS47_RS10240	COG0642	Histidine kinase
AVS47_RS10260	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AVS47_RS10265	COG0336	Belongs to the RNA methyltransferase TrmD family
AVS47_RS10270	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AVS47_RS10275	COG0228	four-way junction DNA binding
AVS47_RS10285	COG0425	Belongs to the sulfur carrier protein TusA family
AVS47_RS10290	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AVS47_RS10335	COG0154	amidase activity
AVS47_RS10340	COG4172	Belongs to the ABC transporter superfamily
AVS47_RS10345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVS47_RS10350	COG0601	transmembrane transport
AVS47_RS10355	COG0747	negative chemotaxis
AVS47_RS10385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AVS47_RS10395	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AVS47_RS10410	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AVS47_RS10415	COG3395	kinase activity
AVS47_RS10430	COG1024	Enoyl-CoA hydratase
AVS47_RS10450	COG0633	Ferredoxin
AVS47_RS10455	COG0443	Heat shock 70 kDa protein
AVS47_RS10460	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AVS47_RS10465	COG0316	Belongs to the HesB IscA family
AVS47_RS10470	COG0822	iron-sulfur transferase activity
AVS47_RS10475	COG1104	cysteine desulfurase activity
AVS47_RS10485	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AVS47_RS10490	COG0556	nucleotide-excision repair
AVS47_RS10500	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AVS47_RS10505	COG3468	outer membrane autotransporter barrel domain protein
AVS47_RS10535	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AVS47_RS10550	COG1960	acyl-CoA dehydrogenase activity
AVS47_RS10555	COG1028	Short-chain dehydrogenase reductase Sdr
AVS47_RS10560	COG0183	Belongs to the thiolase family
AVS47_RS10570	COG1024	Enoyl-CoA hydratase
AVS47_RS10585	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AVS47_RS10590	COG0583	DNA-binding transcription factor activity
AVS47_RS10595	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AVS47_RS10600	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AVS47_RS10605	COG0740	serine-type endopeptidase activity
AVS47_RS10610	COG0544	peptidyl-prolyl cis-trans isomerase activity
AVS47_RS10630	COG1278	Cold shock
AVS47_RS10665	COG2171	N-acyltransferase activity
AVS47_RS10670	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AVS47_RS10675	COG2890	protein-(glutamine-N5) methyltransferase activity
AVS47_RS10680	COG0488	(ABC) transporter
AVS47_RS10685	COG4771	TonB-dependent receptor
AVS47_RS10690	COG0210	DNA helicase
AVS47_RS10710	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AVS47_RS10715	COG0196	riboflavin kinase activity
AVS47_RS10720	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AVS47_RS10725	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AVS47_RS10730	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AVS47_RS10740	COG1522	sequence-specific DNA binding
AVS47_RS10760	COG2951	lytic endotransglycosylase activity
AVS47_RS10765	COG2833	Protein of unknown function (DUF455)
AVS47_RS10785	COG0189	ligase activity
AVS47_RS10785	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AVS47_RS10790	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AVS47_RS10790	COG1181	Belongs to the D-alanine--D-alanine ligase family
AVS47_RS10795	COG3237	CsbD-like
AVS47_RS10805	COG2823	Periplasmic or secreted lipoprotein
AVS47_RS10820	COG4181	ATPase activity
AVS47_RS10830	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AVS47_RS10835	COG0584	glycerophosphoryl diester phosphodiesterase
AVS47_RS10840	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AVS47_RS10850	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AVS47_RS10850	COG0678	peroxiredoxin activity
AVS47_RS10860	COG0789	Transcriptional regulator
AVS47_RS10865	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AVS47_RS10895	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AVS47_RS10900	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AVS47_RS10910	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AVS47_RS10915	COG2252	PERMEase
AVS47_RS10925	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AVS47_RS10955	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AVS47_RS10960	COG2358	TRAP transporter, solute receptor (TAXI family
AVS47_RS10990	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AVS47_RS10995	COG1366	Belongs to the anti-sigma-factor antagonist family
AVS47_RS11000	COG2172	sigma factor antagonist activity
AVS47_RS11005	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AVS47_RS11015	COG2208	phosphoserine phosphatase activity
AVS47_RS11015	COG2770	Histidine kinase
AVS47_RS11040	COG1595	DNA-templated transcription, initiation
AVS47_RS11055	COG4792	protein secretion
AVS47_RS11060	COG4791	protein targeting
AVS47_RS11065	COG4794	Type iii secretion
AVS47_RS11070	COG4790	Type iii secretion
AVS47_RS11105	COG4669	(LipO)protein
AVS47_RS11170	COG4789	Type iii secretion
AVS47_RS11200	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AVS47_RS11205	COG0840	transmembrane signaling receptor activity
AVS47_RS11210	COG2233	PERMEase
AVS47_RS11230	COG0492	ferredoxin-NADP+ reductase activity
AVS47_RS11235	COG1840	ABC-type Fe3 transport system, periplasmic component
AVS47_RS11240	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AVS47_RS11245	COG1178	ABC-type Fe3 transport system permease component
AVS47_RS11250	COG3842	ATPase activity
AVS47_RS11255	COG0583	DNA-binding transcription factor activity
AVS47_RS11275	COG0501	Belongs to the peptidase M48B family
AVS47_RS11285	COG0697	spore germination
AVS47_RS11295	COG1846	Transcriptional regulator
AVS47_RS11305	COG1566	PFAM secretion protein HlyD family protein
AVS47_RS11310	COG2814	Major facilitator Superfamily
AVS47_RS11315	COG0473	3-isopropylmalate dehydrogenase activity
AVS47_RS11325	COG0747	negative chemotaxis
AVS47_RS11335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVS47_RS11350	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AVS47_RS11375	COG1012	belongs to the aldehyde dehydrogenase family
AVS47_RS11385	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AVS47_RS11390	COG1115	amino acid carrier protein
AVS47_RS11395	COG0433	COG0433 Predicted ATPase
AVS47_RS11400	COG0217	transcriptional regulatory protein
AVS47_RS11405	COG0151	Belongs to the GarS family
AVS47_RS11410	COG0408	coproporphyrinogen oxidase activity
AVS47_RS11415	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AVS47_RS11420	COG0799	negative regulation of ribosome biogenesis
AVS47_RS11425	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AVS47_RS11430	COG0424	maF-like protein
AVS47_RS11435	COG3468	outer membrane autotransporter barrel domain protein
AVS47_RS11475	COG1530	ribonuclease E activity
AVS47_RS11480	COG0077	Prephenate dehydratase
AVS47_RS11495	COG1132	(ABC) transporter
AVS47_RS11500	COG0859	PFAM glycosyl transferase family 9
AVS47_RS11525	COG2194	sulfuric ester hydrolase activity
AVS47_RS11530	COG0438	transferase activity, transferring glycosyl groups
AVS47_RS11535	COG0463	Glycosyl transferase, family 2
AVS47_RS11540	COG0726	polysaccharide deacetylase
AVS47_RS11545	COG0438	transferase activity, transferring glycosyl groups
AVS47_RS11560	COG1643	Atp-dependent helicase
AVS47_RS11565	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AVS47_RS11565	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AVS47_RS11570	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AVS47_RS11580	COG0704	Plays a role in the regulation of phosphate uptake
AVS47_RS11585	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AVS47_RS11590	COG1960	acyl-CoA dehydrogenase activity
AVS47_RS11615	COG1177	transmembrane transport
AVS47_RS11620	COG1176	ABC-type spermidine putrescine transport system, permease component I
AVS47_RS11625	COG3842	ATPase activity
AVS47_RS11630	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AVS47_RS11645	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AVS47_RS11650	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AVS47_RS11660	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AVS47_RS11660	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AVS47_RS11680	COG0372	Belongs to the citrate synthase family
AVS47_RS11685	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AVS47_RS11690	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AVS47_RS11695	COG1053	succinate dehydrogenase
AVS47_RS11700	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AVS47_RS11705	COG2009	succinate dehydrogenase
AVS47_RS11710	COG2188	Transcriptional regulator
AVS47_RS11715	COG0039	L-malate dehydrogenase activity
AVS47_RS11745	COG1981	membrane
AVS47_RS11770	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AVS47_RS11780	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AVS47_RS11810	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AVS47_RS11815	COG0148	phosphopyruvate hydratase activity
AVS47_RS11825	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AVS47_RS11830	COG0504	CTP synthase activity
AVS47_RS11855	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVS47_RS11865	COG0747	negative chemotaxis
AVS47_RS11870	COG4172	Belongs to the ABC transporter superfamily
AVS47_RS11875	COG1446	asparaginase
AVS47_RS11905	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AVS47_RS11920	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AVS47_RS11925	COG0697	spore germination
AVS47_RS11930	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AVS47_RS11940	COG3193	protein, possibly involved in utilization of glycolate and propanediol
AVS47_RS11945	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AVS47_RS11950	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AVS47_RS11955	COG0791	NLP P60 protein
AVS47_RS11970	COG0583	DNA-binding transcription factor activity
AVS47_RS11985	COG0583	DNA-binding transcription factor activity
AVS47_RS11995	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AVS47_RS12010	COG0670	Belongs to the BI1 family
AVS47_RS12015	COG3181	Tripartite tricarboxylate transporter family receptor
AVS47_RS12025	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AVS47_RS12035	COG1381	Involved in DNA repair and RecF pathway recombination
AVS47_RS12040	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AVS47_RS12045	COG0571	ribonuclease III activity
AVS47_RS12050	COG0681	Belongs to the peptidase S26 family
AVS47_RS12055	COG0481	GTPase activity
AVS47_RS12060	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AVS47_RS12085	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AVS47_RS12090	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AVS47_RS12105	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AVS47_RS12110	COG0416	fatty acid biosynthetic process
AVS47_RS12115	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AVS47_RS12120	COG1399	metal-binding, possibly nucleic acid-binding protein
AVS47_RS12125	COG0424	maF-like protein
AVS47_RS12135	COG3023	N-Acetylmuramoyl-L-alanine amidase
AVS47_RS12150	COG3022	response to hydroperoxide
AVS47_RS12165	COG0135	phosphoribosylanthranilate isomerase activity
AVS47_RS12180	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AVS47_RS12185	COG0101	tRNA pseudouridine synthase activity
AVS47_RS12195	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AVS47_RS12200	COG0473	3-isopropylmalate dehydrogenase activity
AVS47_RS12205	COG0066	3-isopropylmalate dehydratase activity
AVS47_RS12210	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AVS47_RS12220	COG1122	ATPase activity
AVS47_RS12250	COG0437	4 iron, 4 sulfur cluster binding
AVS47_RS12255	COG3383	formate dehydrogenase (NAD+) activity
AVS47_RS12255	COG0243	molybdopterin cofactor binding
AVS47_RS12285	COG0489	protein tyrosine kinase activity
AVS47_RS12290	COG0746	molybdenum cofactor guanylyltransferase activity
AVS47_RS12295	COG0303	'Molybdopterin
AVS47_RS12300	COG1763	Mo-molybdopterin cofactor biosynthetic process
AVS47_RS12310	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AVS47_RS12315	COG5001	Diguanylate cyclase
AVS47_RS12335	COG3842	ATPase activity
AVS47_RS12345	COG0406	alpha-ribazole phosphatase activity
AVS47_RS12355	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AVS47_RS12360	COG0505	Belongs to the CarA family
AVS47_RS12365	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AVS47_RS12390	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AVS47_RS12395	COG1960	acyl-CoA dehydrogenase activity
AVS47_RS12405	COG2867	negative regulation of translational initiation
AVS47_RS12415	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AVS47_RS12420	COG3706	GGDEF domain
AVS47_RS12425	COG0330	HflC and HflK could
AVS47_RS12440	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AVS47_RS12440	COG0519	Catalyzes the synthesis of GMP from XMP
AVS47_RS12450	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AVS47_RS12455	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AVS47_RS12460	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AVS47_RS12465	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AVS47_RS12475	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AVS47_RS12480	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AVS47_RS12485	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
AVS47_RS12490	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AVS47_RS12495	COG0750	zinc metalloprotease
AVS47_RS12500	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AVS47_RS12510	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AVS47_RS12515	COG0233	cytoplasmic translational termination
AVS47_RS12520	COG0528	UMP kinase activity
AVS47_RS12525	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AVS47_RS12530	COG0052	Belongs to the universal ribosomal protein uS2 family
AVS47_RS12535	COG0024	Methionine aminopeptidase
AVS47_RS12540	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AVS47_RS12570	COG0285	dihydrofolate synthase activity
AVS47_RS12605	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AVS47_RS12615	COG1677	Flagellar hook-basal body complex protein FliE
AVS47_RS12625	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AVS47_RS12635	COG1157	protein secretion by the type III secretion system
AVS47_RS12660	COG1580	Controls the rotational direction of flagella during chemotaxis
AVS47_RS12680	COG1338	Plays a role in the flagellum-specific transport system
AVS47_RS12700	COG0840	transmembrane signaling receptor activity
AVS47_RS12705	COG0840	transmembrane signaling receptor activity
AVS47_RS12710	COG0840	transmembrane signaling receptor activity
AVS47_RS12720	COG1256	bacterial-type flagellum assembly
AVS47_RS12730	COG1706	bacterial-type flagellum-dependent cell motility
AVS47_RS12735	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AVS47_RS12750	COG1749	Flagellar hook protein flgE
AVS47_RS12760	COG1558	bacterial-type flagellum-dependent cell motility
AVS47_RS12765	COG1815	bacterial-type flagellum-dependent cell motility
AVS47_RS12805	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVS47_RS12810	COG0765	amino acid transport
AVS47_RS12815	COG1126	abc transporter atp-binding protein
AVS47_RS12830	COG4948	Mandelate Racemase Muconate Lactonizing
AVS47_RS12835	COG3181	Tripartite tricarboxylate transporter family receptor
AVS47_RS12845	COG0066	3-isopropylmalate dehydratase activity
AVS47_RS12860	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AVS47_RS12870	COG3181	Tripartite tricarboxylate transporter family receptor
AVS47_RS12880	COG1802	Transcriptional regulator
AVS47_RS12895	COG0583	DNA-binding transcription factor activity
AVS47_RS12915	COG1695	Transcriptional regulator
AVS47_RS12925	COG3568	Endonuclease Exonuclease Phosphatase
AVS47_RS12930	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AVS47_RS12945	COG0392	lysyltransferase activity
AVS47_RS12985	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AVS47_RS12995	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AVS47_RS13015	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AVS47_RS13045	COG0667	Aldo Keto reductase
AVS47_RS13060	COG2259	Doxx family
AVS47_RS13090	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AVS47_RS13110	COG0386	Belongs to the glutathione peroxidase family
AVS47_RS13115	COG0625	glutathione transferase activity
AVS47_RS13140	COG0688	phosphatidylethanolamine metabolic process
AVS47_RS13150	COG1464	Belongs to the NlpA lipoprotein family
AVS47_RS13165	COG2363	Small membrane protein
AVS47_RS13190	COG3842	ATPase activity
AVS47_RS13195	COG0395	ABC-type sugar transport system, permease component
AVS47_RS13200	COG1175	transmembrane transport
AVS47_RS13205	COG1653	transport
AVS47_RS13215	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AVS47_RS13230	COG0559	Belongs to the binding-protein-dependent transport system permease family
AVS47_RS13250	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AVS47_RS13265	COG0697	spore germination
AVS47_RS13275	COG2311	Membrane
AVS47_RS13300	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AVS47_RS13310	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AVS47_RS13315	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AVS47_RS13320	COG1760	l-serine dehydratase
AVS47_RS13325	COG1283	sodium-dependent phosphate transmembrane transporter activity
AVS47_RS13330	COG0412	Dienelactone hydrolase
AVS47_RS13345	COG1611	Belongs to the LOG family
AVS47_RS13365	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AVS47_RS13370	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AVS47_RS13375	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AVS47_RS13380	COG2251	uridine kinase activity
AVS47_RS13380	COG0195	Participates in both transcription termination and antitermination
AVS47_RS13385	COG0779	Required for maturation of 30S ribosomal subunits
AVS47_RS13390	COG1187	pseudouridine synthase activity
AVS47_RS13395	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AVS47_RS13405	COG0583	DNA-binding transcription factor activity
AVS47_RS13415	COG0523	cobalamin synthesis protein
AVS47_RS13435	COG0625	glutathione transferase activity
AVS47_RS13440	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AVS47_RS13445	COG1047	Peptidyl-prolyl cis-trans
AVS47_RS13450	COG2003	Belongs to the UPF0758 family
AVS47_RS13455	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AVS47_RS13460	COG3483	tryptophan 2,3-dioxygenase activity
AVS47_RS13465	COG0254	rRNA binding
AVS47_RS13475	COG0534	Mate efflux family protein
AVS47_RS13495	COG2304	oxidoreductase activity
AVS47_RS13515	COG1028	Short-chain dehydrogenase reductase Sdr
AVS47_RS13520	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AVS47_RS13525	COG1562	ergosterol biosynthetic process
AVS47_RS13530	COG1562	ergosterol biosynthetic process
AVS47_RS13535	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
AVS47_RS13535	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
AVS47_RS13540	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AVS47_RS13550	COG0842	Transport permease protein
AVS47_RS13555	COG1131	(ABC) transporter
AVS47_RS13575	COG1477	protein flavinylation
AVS47_RS13590	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AVS47_RS13605	COG5564	TIM-barrel signal transduction protein
AVS47_RS13610	COG5441	Belongs to the UPF0261 family
AVS47_RS13620	COG3468	outer membrane autotransporter barrel domain protein
AVS47_RS13625	COG3468	outer membrane autotransporter barrel domain protein
AVS47_RS13640	COG0542	response to heat
AVS47_RS13645	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AVS47_RS13660	COG0494	nUDIX hydrolase
AVS47_RS13665	COG3530	Putative quorum-sensing-regulated virulence factor
AVS47_RS13675	COG1595	DNA-templated transcription, initiation
AVS47_RS13680	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AVS47_RS13715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVS47_RS13720	COG0765	amino acid transport
AVS47_RS13725	COG0765	amino acid transport
AVS47_RS13755	COG2988	succinylglutamate desuccinylase activity
AVS47_RS13780	COG3181	Tripartite tricarboxylate transporter family receptor
AVS47_RS13785	COG2084	Dehydrogenase
AVS47_RS13800	COG1619	proteins homologs of microcin C7 resistance protein MccF
AVS47_RS13815	COG2814	Major facilitator Superfamily
AVS47_RS13825	COG0583	DNA-binding transcription factor activity
AVS47_RS13865	COG0672	)-iron permease
AVS47_RS13880	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
AVS47_RS13885	COG1028	Short-chain dehydrogenase reductase Sdr
AVS47_RS13890	COG3243	poly(R)-hydroxyalkanoic acid synthase
AVS47_RS13900	COG0564	pseudouridine synthase activity
AVS47_RS13910	COG1199	ATP-dependent helicase activity
AVS47_RS13915	COG2183	response to ionizing radiation
AVS47_RS13920	COG0180	Tryptophanyl-tRNA synthetase
AVS47_RS13945	COG3181	Tripartite tricarboxylate transporter family receptor
AVS47_RS13955	COG0583	DNA-binding transcription factor activity
AVS47_RS13960	COG1028	Short-chain dehydrogenase reductase Sdr
AVS47_RS13965	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AVS47_RS13970	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AVS47_RS13975	COG0508	dehydrogenase complex catalyzes the overall conversion of
AVS47_RS13980	COG0567	Dehydrogenase, E1 component
AVS47_RS13990	COG1522	sequence-specific DNA binding
AVS47_RS14000	COG0280	phosphate acetyltransferase
AVS47_RS14000	COG0281	malic enzyme
AVS47_RS14005	COG3539	Fimbrial protein
AVS47_RS14020	COG0613	PHP domain protein
AVS47_RS14030	COG0658	competence protein
AVS47_RS14030	COG2333	competence protein COMEC
AVS47_RS14060	COG0084	hydrolase, TatD family'
AVS47_RS14065	COG1136	(ABC) transporter
AVS47_RS14080	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AVS47_RS14090	COG1028	Short-chain dehydrogenase reductase Sdr
AVS47_RS14095	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AVS47_RS14110	COG1022	Amp-dependent synthetase and ligase
AVS47_RS14145	COG2205	protein histidine kinase activity
AVS47_RS14150	COG0745	RESPONSE REGULATOR receiver
AVS47_RS14155	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AVS47_RS14165	COG1295	ribonuclease BN
AVS47_RS14180	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AVS47_RS14210	COG1534	Rna-binding protein
AVS47_RS14215	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AVS47_RS14220	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AVS47_RS14230	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AVS47_RS14240	COG0248	Ppx GppA phosphatase
AVS47_RS14265	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AVS47_RS14280	COG2732	(Barnase) inhibitor
AVS47_RS14290	COG0281	malic enzyme
AVS47_RS14290	COG0280	phosphate acetyltransferase
AVS47_RS14300	COG0436	Aminotransferase
AVS47_RS14305	COG0741	lytic transglycosylase activity
AVS47_RS14310	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AVS47_RS14335	COG1648	precorrin-2 dehydrogenase activity
AVS47_RS14335	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AVS47_RS14340	COG3468	outer membrane autotransporter barrel domain protein
AVS47_RS14350	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AVS47_RS14355	COG2027	D-alanyl-D-alanine carboxypeptidase
AVS47_RS14360	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AVS47_RS14365	COG0343	queuine tRNA-ribosyltransferase activity
AVS47_RS14370	COG1862	Preprotein translocase
AVS47_RS14375	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AVS47_RS14380	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AVS47_RS14395	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AVS47_RS14400	COG1702	phosphate starvation-inducible protein PhoH
AVS47_RS14405	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AVS47_RS14410	COG4535	Mg2 and Co2 transporter CorC
AVS47_RS14420	COG0667	Aldo Keto reductase
AVS47_RS14445	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AVS47_RS14450	COG0745	RESPONSE REGULATOR receiver
AVS47_RS14455	COG2201	protein-glutamate methylesterase activity
AVS47_RS14465	COG0840	transmembrane signaling receptor activity
AVS47_RS14480	COG0745	RESPONSE REGULATOR receiver
AVS47_RS14515	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AVS47_RS14525	COG0739	heme binding
AVS47_RS14535	COG0521	Mo-molybdopterin cofactor biosynthetic process
AVS47_RS14545	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AVS47_RS14580	COG0625	glutathione transferase activity
AVS47_RS14595	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AVS47_RS14600	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AVS47_RS14605	COG0126	phosphoglycerate kinase activity
AVS47_RS14610	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AVS47_RS14615	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AVS47_RS14620	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AVS47_RS14630	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AVS47_RS14635	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AVS47_RS14640	COG0508	dehydrogenase complex catalyzes the overall conversion of
AVS47_RS14645	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AVS47_RS14655	COG4566	intracellular signal transduction
AVS47_RS14660	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AVS47_RS14665	COG0339	signal peptide processing
AVS47_RS14670	COG1999	signal sequence binding
AVS47_RS14690	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AVS47_RS14700	COG1187	pseudouridine synthase activity
AVS47_RS14705	COG3161	chorismate lyase activity
AVS47_RS14710	COG2814	Major facilitator Superfamily
AVS47_RS14720	COG0667	Aldo Keto reductase
AVS47_RS14735	COG0335	large ribosomal subunit rRNA binding
AVS47_RS14765	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AVS47_RS14770	COG4208	sulfate ABC transporter
AVS47_RS14775	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AVS47_RS14790	COG0450	alkyl hydroperoxide reductase
AVS47_RS14795	COG1960	acyl-CoA dehydrogenase activity
AVS47_RS14810	COG0123	including yeast histone deacetylase and acetoin utilization protein
AVS47_RS14815	COG2951	lytic endotransglycosylase activity
AVS47_RS14830	COG1596	polysaccharide export
AVS47_RS14830	COG1555	photosystem II stabilization
AVS47_RS14835	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AVS47_RS14840	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AVS47_RS14845	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AVS47_RS14865	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AVS47_RS14870	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AVS47_RS14875	COG0287	Prephenate dehydrogenase
AVS47_RS14885	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AVS47_RS14900	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AVS47_RS14910	COG2814	Major facilitator Superfamily
AVS47_RS14935	COG0583	DNA-binding transcription factor activity
AVS47_RS14975	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AVS47_RS14990	COG0667	Aldo Keto reductase
AVS47_RS15000	COG5265	(ABC) transporter
AVS47_RS15045	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AVS47_RS15050	COG0439	Biotin carboxylase
AVS47_RS15055	COG2188	Transcriptional regulator
AVS47_RS15080	COG0511	ligase activity, forming carbon-carbon bonds
AVS47_RS15090	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AVS47_RS15110	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
AVS47_RS15130	COG0500	methyltransferase
AVS47_RS15135	COG5265	(ABC) transporter
AVS47_RS15150	COG0028	Belongs to the TPP enzyme family
AVS47_RS15155	COG0440	acetolactate synthase activity
AVS47_RS15160	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AVS47_RS15165	COG1183	phosphatidylcholine synthase activity
AVS47_RS15180	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AVS47_RS15185	COG1185	polyribonucleotide nucleotidyltransferase activity
AVS47_RS15200	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AVS47_RS15220	COG0149	triose-phosphate isomerase activity
AVS47_RS15225	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AVS47_RS15235	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AVS47_RS15245	COG3799	methylaspartate ammonia-lyase activity
AVS47_RS15280	COG0583	DNA-binding transcription factor activity
AVS47_RS15285	COG0626	cystathionine gamma-synthase activity
AVS47_RS15290	COG3608	succinylglutamate desuccinylase aspartoacylase
AVS47_RS15310	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AVS47_RS15330	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
AVS47_RS15345	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AVS47_RS15350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AVS47_RS15355	COG1733	regulation of RNA biosynthetic process
AVS47_RS15365	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AVS47_RS15370	COG0583	DNA-binding transcription factor activity
AVS47_RS15375	COG1597	lipid kinase activity
AVS47_RS15385	COG0671	phosphoesterase, PA-phosphatase related
AVS47_RS15415	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AVS47_RS15420	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AVS47_RS15425	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AVS47_RS15430	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AVS47_RS15435	COG0649	NAD binding
AVS47_RS15440	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AVS47_RS15450	COG1034	ATP synthesis coupled electron transport
AVS47_RS15455	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AVS47_RS15460	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AVS47_RS15470	COG0713	ATP synthesis coupled electron transport
AVS47_RS15485	COG1007	ATP synthesis coupled electron transport
AVS47_RS15495	COG4774	siderophore transport
AVS47_RS15500	COG4774	siderophore transport
AVS47_RS15515	COG0028	Belongs to the TPP enzyme family
AVS47_RS15520	COG3181	Tripartite tricarboxylate transporter family receptor
AVS47_RS15525	COG0583	DNA-binding transcription factor activity
AVS47_RS15530	COG0560	Phosphoserine phosphatase
AVS47_RS15535	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AVS47_RS15540	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AVS47_RS15545	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AVS47_RS15555	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AVS47_RS15560	COG0308	aminopeptidase N
AVS47_RS15580	COG0028	Belongs to the TPP enzyme family
AVS47_RS15600	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AVS47_RS15610	COG0318	PFAM AMP-dependent synthetase and ligase
AVS47_RS15620	COG1802	Transcriptional regulator
AVS47_RS15630	COG1802	Transcriptional regulator
AVS47_RS15640	COG1028	Short-chain dehydrogenase reductase Sdr
AVS47_RS15660	COG1126	abc transporter atp-binding protein
AVS47_RS15665	COG0765	amino acid transport
AVS47_RS15670	COG0765	amino acid transport
AVS47_RS15690	COG1538	Outer membrane efflux protein
AVS47_RS15695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AVS47_RS15700	COG2274	protein secretion by the type I secretion system
AVS47_RS15705	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
AVS47_RS15715	COG2994	toxin metabolic process
AVS47_RS15730	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AVS47_RS15735	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
AVS47_RS15745	COG0583	DNA-binding transcription factor activity
AVS47_RS15755	COG0142	geranyltranstransferase activity
AVS47_RS15765	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AVS47_RS15770	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AVS47_RS15775	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AVS47_RS15780	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AVS47_RS15825	COG3712	iron ion homeostasis
AVS47_RS15830	COG4774	siderophore transport
AVS47_RS15835	COG2353	YceI-like domain
AVS47_RS15850	COG0019	diaminopimelate decarboxylase activity
AVS47_RS15870	COG0747	negative chemotaxis
AVS47_RS15875	COG0601	transmembrane transport
AVS47_RS15880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVS47_RS15890	COG0154	amidase activity
AVS47_RS15895	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AVS47_RS15920	COG2154	pterin-4-alpha-carbinolamine dehydratase
AVS47_RS15930	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AVS47_RS15940	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AVS47_RS15945	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AVS47_RS15950	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AVS47_RS15955	COG1929	Belongs to the glycerate kinase type-1 family
AVS47_RS15960	COG0469	pyruvate kinase activity
AVS47_RS15965	COG0700	Nucleoside recognition
AVS47_RS16000	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AVS47_RS16005	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AVS47_RS16020	COG0823	Involved in the tonB-independent uptake of proteins
AVS47_RS16030	COG0848	biopolymer transport protein
AVS47_RS16035	COG0811	peptide transport
AVS47_RS16040	COG0824	Thioesterase
AVS47_RS16045	COG0442	prolyl-tRNA aminoacylation
AVS47_RS16050	COG0494	nUDIX hydrolase
AVS47_RS16065	COG2135	peptidase activity
AVS47_RS16135	COG1196	nuclear chromosome segregation
AVS47_RS16280	COG1464	Belongs to the NlpA lipoprotein family
AVS47_RS16310	COG4211	Belongs to the binding-protein-dependent transport system permease family
AVS47_RS16320	COG0154	amidase activity
AVS47_RS16325	COG0288	reversible hydration of carbon dioxide
AVS47_RS16340	COG0514	ATP-dependent DNA helicase (RecQ)
AVS47_RS16345	COG2255	four-way junction helicase activity
AVS47_RS16360	COG0632	four-way junction helicase activity
AVS47_RS16365	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AVS47_RS16385	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AVS47_RS16395	COG0006	proline dipeptidase activity
AVS47_RS16420	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AVS47_RS16435	COG4783	chaperone-mediated protein folding
AVS47_RS16440	COG0429	hydrolase of the alpha beta-hydrolase fold
AVS47_RS16470	COG0513	Belongs to the DEAD box helicase family
AVS47_RS16490	COG1546	Belongs to the CinA family
AVS47_RS16490	COG1058	Belongs to the CinA family
AVS47_RS16495	COG1414	Transcriptional regulator
AVS47_RS16515	COG0167	dihydroorotate dehydrogenase activity
AVS47_RS16520	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AVS47_RS16525	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AVS47_RS16535	COG0583	DNA-binding transcription factor activity
AVS47_RS16595	COG0280	phosphate acetyltransferase
AVS47_RS16595	COG0281	malic enzyme
AVS47_RS16605	COG0601	transmembrane transport
AVS47_RS16610	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVS47_RS16615	COG4172	Belongs to the ABC transporter superfamily
AVS47_RS16645	COG0640	Transcriptional regulator
AVS47_RS16660	COG3135	benzoate transporter
AVS47_RS16665	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AVS47_RS16670	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AVS47_RS16675	COG0742	ribosomal rna small subunit methyltransferase
AVS47_RS16690	COG3639	organic phosphonate transmembrane transporter activity
AVS47_RS16695	COG3639	organic phosphonate transmembrane transporter activity
AVS47_RS16700	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AVS47_RS16735	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AVS47_RS16740	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AVS47_RS16750	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AVS47_RS16755	COG1058	Belongs to the CinA family
AVS47_RS16755	COG1546	Belongs to the CinA family
AVS47_RS16760	COG0284	orotidine-5'-phosphate decarboxylase activity
AVS47_RS16765	COG1252	NADH dehydrogenase
AVS47_RS16780	COG3468	outer membrane autotransporter barrel domain protein
AVS47_RS16785	COG0459	protein refolding
AVS47_RS16790	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AVS47_RS16810	COG1053	succinate dehydrogenase
AVS47_RS16820	COG0583	DNA-binding transcription factor activity
AVS47_RS16825	COG1053	succinate dehydrogenase
AVS47_RS16845	COG3706	GGDEF domain
AVS47_RS16880	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AVS47_RS16885	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
AVS47_RS16895	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AVS47_RS16905	COG0069	glutamate synthase activity
AVS47_RS16910	COG2391	methyltransferase activity
AVS47_RS16915	COG0679	Auxin Efflux Carrier
AVS47_RS16940	COG0557	exoribonuclease II activity
AVS47_RS16945	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AVS47_RS16955	COG3128	pkhd-type hydroxylase
AVS47_RS16960	COG0776	regulation of translation
AVS47_RS16990	COG0642	Histidine kinase
AVS47_RS16995	COG3158	transport of potassium into the cell
AVS47_RS17000	COG0137	argininosuccinate synthase activity
AVS47_RS17005	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AVS47_RS17010	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AVS47_RS17020	COG0583	DNA-binding transcription factor activity
AVS47_RS17030	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AVS47_RS17050	COG2186	Transcriptional regulator
AVS47_RS17060	COG2223	nitrite transmembrane transporter activity
AVS47_RS17070	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AVS47_RS17075	COG0450	alkyl hydroperoxide reductase
AVS47_RS17095	COG1214	PFAM Peptidase M22, glycoprotease
AVS47_RS17100	COG1573	uracil-dna glycosylase
AVS47_RS17105	COG0477	Major facilitator Superfamily
AVS47_RS17110	COG1196	nuclear chromosome segregation
AVS47_RS17120	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AVS47_RS17125	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AVS47_RS17140	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AVS47_RS17145	COG1122	ATPase activity
AVS47_RS17150	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AVS47_RS17155	COG1268	BioY protein
AVS47_RS17175	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AVS47_RS17210	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AVS47_RS17215	COG2878	Part of a membrane complex involved in electron transport
AVS47_RS17230	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AVS47_RS17235	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AVS47_RS17240	COG0251	oxidation-reduction process
AVS47_RS17250	COG3228	Belongs to the MtfA family
AVS47_RS17255	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AVS47_RS17265	COG0133	tryptophan synthase activity
AVS47_RS17270	COG0159	tryptophan synthase activity
AVS47_RS17275	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AVS47_RS17280	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AVS47_RS17295	COG1530	ribonuclease E activity
AVS47_RS17305	COG0546	phosphoglycolate phosphatase activity
AVS47_RS17310	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AVS47_RS17315	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AVS47_RS17325	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AVS47_RS17330	COG0583	DNA-binding transcription factor activity
AVS47_RS17340	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AVS47_RS17360	COG0251	oxidation-reduction process
AVS47_RS17365	COG1017	nitric oxide dioxygenase activity
AVS47_RS17365	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AVS47_RS17370	COG2031	fatty acid transporter
AVS47_RS17375	COG1012	belongs to the aldehyde dehydrogenase family
AVS47_RS17380	COG1802	Transcriptional regulator
AVS47_RS17390	COG1278	Cold shock
AVS47_RS17395	COG0583	DNA-binding transcription factor activity
AVS47_RS17415	COG0183	Belongs to the thiolase family
AVS47_RS17425	COG1960	acyl-CoA dehydrogenase activity
AVS47_RS17430	COG0583	DNA-binding transcription factor activity
AVS47_RS17435	COG3181	Tripartite tricarboxylate transporter family receptor
AVS47_RS17440	COG1024	Enoyl-CoA hydratase
AVS47_RS17445	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AVS47_RS17450	COG1253	flavin adenine dinucleotide binding
AVS47_RS17455	COG1285	pathogenesis
AVS47_RS17465	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AVS47_RS17480	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AVS47_RS17490	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AVS47_RS17500	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AVS47_RS17505	COG3181	Tripartite tricarboxylate transporter family receptor
AVS47_RS17510	COG1960	acyl-CoA dehydrogenase activity
AVS47_RS17530	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AVS47_RS17535	COG1024	Enoyl-CoA hydratase
AVS47_RS17540	COG1960	acyl-CoA dehydrogenase activity
AVS47_RS17560	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AVS47_RS17565	COG0022	dehydrogenase e1 component
AVS47_RS17570	COG1024	Enoyl-CoA hydratase
AVS47_RS17575	COG0508	dehydrogenase complex catalyzes the overall conversion of
AVS47_RS17595	COG0683	leucine binding
AVS47_RS17600	COG0559	Belongs to the binding-protein-dependent transport system permease family
AVS47_RS17605	COG0411	ABC transporter
AVS47_RS17615	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AVS47_RS17630	COG3181	Tripartite tricarboxylate transporter family receptor
AVS47_RS17660	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AVS47_RS17665	COG0793	Belongs to the peptidase S41A family
AVS47_RS17670	COG4942	peptidase
AVS47_RS17675	COG0588	phosphoglycerate mutase activity
AVS47_RS17680	COG1054	Belongs to the UPF0176 family
AVS47_RS17685	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AVS47_RS17690	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AVS47_RS17695	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AVS47_RS17700	COG3181	Tripartite tricarboxylate transporter family receptor
AVS47_RS17715	COG2226	methyltransferase
AVS47_RS17720	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AVS47_RS17735	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AVS47_RS17740	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AVS47_RS17765	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AVS47_RS17790	COG1335	isochorismatase
AVS47_RS17795	COG2309	aminopeptidase activity
AVS47_RS17800	COG0596	Alpha beta hydrolase
AVS47_RS17805	COG3473	Maleate cis-trans isomerase
AVS47_RS17815	COG2068	MobA-Related Protein
AVS47_RS17840	COG2204	response regulator
AVS47_RS17845	COG5000	phosphorelay sensor kinase activity
AVS47_RS17855	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AVS47_RS17855	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AVS47_RS17865	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
AVS47_RS17895	COG0583	DNA-binding transcription factor activity
AVS47_RS17910	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AVS47_RS17915	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AVS47_RS17920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVS47_RS17935	COG0758	DNA mediated transformation
AVS47_RS17940	COG1522	sequence-specific DNA binding
AVS47_RS17950	COG0242	peptide deformylase activity
AVS47_RS17965	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AVS47_RS17975	COG0546	phosphoglycolate phosphatase activity
AVS47_RS17995	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AVS47_RS18000	COG1942	4-Oxalocrotonate Tautomerase
AVS47_RS18005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AVS47_RS18030	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AVS47_RS18050	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AVS47_RS18055	COG1024	Enoyl-CoA hydratase
AVS47_RS18060	COG1414	Transcriptional regulator
AVS47_RS18065	COG0318	PFAM AMP-dependent synthetase and ligase
AVS47_RS18070	COG3181	Tripartite tricarboxylate transporter family receptor
AVS47_RS18100	COG0583	DNA-binding transcription factor activity
AVS47_RS18115	COG3422	double-strand break repair
AVS47_RS18120	COG0330	HflC and HflK could
AVS47_RS18130	COG0251	oxidation-reduction process
AVS47_RS18175	COG3723	Recombinational DNA repair protein, rece pathway
AVS47_RS18210	COG0582	viral genome integration into host DNA
AVS47_RS18235	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AVS47_RS18245	COG0706	membrane insertase activity
AVS47_RS18250	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AVS47_RS18255	COG0594	ribonuclease P activity
AVS47_RS18260	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AVS47_RS18265	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AVS47_RS18280	COG1414	Transcriptional regulator
AVS47_RS18285	COG0154	amidase activity
AVS47_RS18300	COG1304	FMN binding
AVS47_RS18320	COG1960	acyl-CoA dehydrogenase activity
AVS47_RS18340	COG1960	acyl-CoA dehydrogenase activity
AVS47_RS18355	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AVS47_RS18370	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AVS47_RS18375	COG3181	Tripartite tricarboxylate transporter family receptor
AVS47_RS18385	COG2358	TRAP transporter, solute receptor (TAXI family
AVS47_RS18395	COG1629	transport
AVS47_RS18400	COG2922	Belongs to the Smg family
AVS47_RS18425	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AVS47_RS18430	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AVS47_RS18435	COG1028	Short-chain dehydrogenase reductase Sdr
AVS47_RS18440	COG1012	belongs to the aldehyde dehydrogenase family
AVS47_RS18450	COG0028	Belongs to the TPP enzyme family
AVS47_RS18455	COG1522	sequence-specific DNA binding
AVS47_RS18460	COG3781	membrane
AVS47_RS18470	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AVS47_RS18490	COG4206	TonB-dependent receptor
AVS47_RS18495	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AVS47_RS18500	COG2022	thiamine diphosphate biosynthetic process
AVS47_RS18505	COG0351	phosphomethylpyrimidine kinase
AVS47_RS18510	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AVS47_RS18525	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AVS47_RS18535	COG0628	permease
AVS47_RS18545	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AVS47_RS18555	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AVS47_RS18560	COG0049	tRNA binding
AVS47_RS18565	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AVS47_RS18570	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AVS47_RS18575	COG0051	transcription antitermination factor activity, RNA binding
AVS47_RS18580	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AVS47_RS18585	COG0088	Forms part of the polypeptide exit tunnel
AVS47_RS18590	COG0089	rRNA binding
AVS47_RS18595	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AVS47_RS18600	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AVS47_RS18605	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AVS47_RS18610	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AVS47_RS18615	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AVS47_RS18620	COG0255	Belongs to the universal ribosomal protein uL29 family
AVS47_RS18625	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AVS47_RS18645	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AVS47_RS18650	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AVS47_RS18655	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AVS47_RS18660	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AVS47_RS18665	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AVS47_RS18670	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AVS47_RS18675	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AVS47_RS18680	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AVS47_RS18685	COG1841	ribosomal large subunit assembly
AVS47_RS18690	COG0200	Binds to the 23S rRNA
AVS47_RS18695	COG0201	protein transport
AVS47_RS18700	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AVS47_RS18705	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AVS47_RS18710	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AVS47_RS18715	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AVS47_RS18720	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AVS47_RS18725	COG0202	RNA polymerase activity
AVS47_RS18730	COG0203	ribosomal protein L17
AVS47_RS18735	COG0537	adenosine 5'-monophosphoramidase activity
AVS47_RS18740	COG1324	tolerance protein
AVS47_RS18745	COG4232	protein-disulfide reductase activity
AVS47_RS18760	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AVS47_RS18770	COG1333	cytochrome c biogenesis protein
AVS47_RS18775	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AVS47_RS18790	COG1965	Belongs to the frataxin family
AVS47_RS18800	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AVS47_RS18805	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AVS47_RS18810	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AVS47_RS18825	COG2814	Major facilitator Superfamily
AVS47_RS18830	COG0629	single-stranded DNA binding
AVS47_RS18870	COG0402	S-adenosylhomocysteine deaminase activity
AVS47_RS18880	COG0438	transferase activity, transferring glycosyl groups
AVS47_RS18900	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AVS47_RS18925	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AVS47_RS18930	COG2186	Transcriptional regulator
AVS47_RS18950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AVS47_RS18955	COG1956	GAF domain-containing protein
AVS47_RS18960	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AVS47_RS18975	COG1652	LysM domain
AVS47_RS18990	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AVS47_RS19005	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AVS47_RS19035	COG3181	Tripartite tricarboxylate transporter family receptor
AVS47_RS19050	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AVS47_RS19065	COG1024	Enoyl-CoA hydratase
AVS47_RS19080	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AVS47_RS19085	COG1309	transcriptional regulator
AVS47_RS19090	COG2816	NAD+ diphosphatase activity
AVS47_RS19095	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AVS47_RS19185	COG2814	Major facilitator Superfamily
AVS47_RS19190	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AVS47_RS19210	COG1999	signal sequence binding
AVS47_RS19215	COG0109	protoheme IX farnesyltransferase activity
AVS47_RS19255	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AVS47_RS19275	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AVS47_RS19280	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AVS47_RS19290	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AVS47_RS19295	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AVS47_RS19305	COG0069	glutamate synthase activity
AVS47_RS19305	COG0067	glutamate synthase
AVS47_RS19305	COG0070	glutamate synthase
AVS47_RS19315	COG3047	cAMP biosynthetic process
AVS47_RS19325	COG1127	ABC transporter
AVS47_RS19330	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AVS47_RS19335	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AVS47_RS19340	COG2853	Lipoprotein
AVS47_RS19350	COG1131	(ABC) transporter
AVS47_RS19355	COG0842	Transport permease protein
AVS47_RS19365	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AVS47_RS19370	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AVS47_RS19375	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AVS47_RS19380	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AVS47_RS19385	COG0131	Imidazoleglycerol-phosphate dehydratase
AVS47_RS19390	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AVS47_RS19395	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AVS47_RS19400	COG0107	imidazoleglycerol-phosphate synthase activity
AVS47_RS19405	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AVS47_RS19410	COG0140	phosphoribosyl-ATP diphosphatase activity
AVS47_RS19415	COG0537	adenosine 5'-monophosphoramidase activity
AVS47_RS19420	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AVS47_RS19425	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AVS47_RS19440	COG3181	Tripartite tricarboxylate transporter family receptor
AVS47_RS19475	COG3702	type iv secretory pathway
AVS47_RS19480	COG3451	type IV secretory pathway VirB4
AVS47_RS19495	COG3736	Type IV secretory pathway, component VirB8
AVS47_RS19500	COG3504	Conjugal transfer protein
AVS47_RS19505	COG2948	multi-organism process
AVS47_RS19510	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
AVS47_RS19520	COG0697	spore germination
AVS47_RS19540	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AVS47_RS19545	COG0747	negative chemotaxis
AVS47_RS19550	COG0601	transmembrane transport
AVS47_RS19555	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVS47_RS19560	COG0444	Belongs to the ABC transporter superfamily
AVS47_RS19570	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AVS47_RS19580	COG0494	nUDIX hydrolase
AVS47_RS19620	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
AVS47_RS19625	COG0237	dephospho-CoA kinase activity
AVS47_RS19630	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AVS47_RS19645	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AVS47_RS19650	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AVS47_RS19660	COG0477	Major facilitator Superfamily
AVS47_RS19665	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AVS47_RS19680	COG1126	abc transporter atp-binding protein
AVS47_RS19685	COG0765	amino acid transport
AVS47_RS19690	COG4597	amino acid ABC transporter
AVS47_RS19695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVS47_RS19700	COG2884	Cell division ATP-binding protein ftsE
AVS47_RS19705	COG2177	Part of the ABC transporter FtsEX involved in
AVS47_RS19710	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AVS47_RS19720	COG1194	a g-specific adenine glycosylase
AVS47_RS19730	COG2226	methyltransferase
AVS47_RS19740	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AVS47_RS19745	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AVS47_RS19760	COG1024	Enoyl-CoA hydratase
AVS47_RS19780	COG1024	Enoyl-CoA hydratase
AVS47_RS19785	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AVS47_RS19790	COG3181	Tripartite tricarboxylate transporter family receptor
AVS47_RS19800	COG0753	catalase activity
AVS47_RS19805	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AVS47_RS19810	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AVS47_RS19820	COG2175	clavaminate synthase activity
AVS47_RS19825	COG1473	amidohydrolase
AVS47_RS19830	COG4608	Belongs to the ABC transporter superfamily
AVS47_RS19835	COG0444	Belongs to the ABC transporter superfamily
AVS47_RS19850	COG0747	negative chemotaxis
AVS47_RS19855	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AVS47_RS19890	COG0436	Aminotransferase
AVS47_RS19895	COG1278	Cold shock