locus-tag	class	description
RD05_RS00005	COG0445	tRNA wobble uridine modification
RD05_RS00010	COG0357	Ribosomal RNA small subunit methyltransferase G
RD05_RS00015	COG1192	Involved in chromosome partitioning
RD05_RS00025	COG1475	DNA binding
RD05_RS00030	COG0252	asparaginase activity
RD05_RS00055	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
RD05_RS00065	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
RD05_RS00075	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
RD05_RS00080	COG0081	regulation of translation
RD05_RS00085	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
RD05_RS00090	COG0222	ribosome binding
RD05_RS00095	COG0085	RNA polymerase activity
RD05_RS00100	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
RD05_RS00140	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD05_RS00165	COG1024	Enoyl-CoA hydratase
RD05_RS00185	COG0752	glycyl-tRNA synthetase alpha subunit
RD05_RS00190	COG0751	glycine-tRNA ligase activity
RD05_RS00195	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
RD05_RS00200	COG0204	Acyl-transferase
RD05_RS00215	COG0242	peptide deformylase activity
RD05_RS00250	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
RD05_RS00255	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
RD05_RS00260	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
RD05_RS00260	COG2813	Specifically methylates the guanine in position
RD05_RS00270	COG2223	nitrite transmembrane transporter activity
RD05_RS00280	COG1794	racemase activity, acting on amino acids and derivatives
RD05_RS00285	COG1126	abc transporter atp-binding protein
RD05_RS00290	COG0765	amino acid transport
RD05_RS00295	COG0765	amino acid transport
RD05_RS00300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RD05_RS00360	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
RD05_RS00390	COG0326	Molecular chaperone. Has ATPase activity
RD05_RS00395	COG0625	glutathione transferase activity
RD05_RS00410	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
RD05_RS00415	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
RD05_RS00445	COG0438	transferase activity, transferring glycosyl groups
RD05_RS00450	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
RD05_RS00455	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
RD05_RS00485	COG0859	PFAM glycosyl transferase family 9
RD05_RS00500	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
RD05_RS00510	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
RD05_RS00515	COG1127	ABC transporter
RD05_RS00540	COG1686	Belongs to the peptidase S11 family
RD05_RS00550	COG2921	Belongs to the UPF0250 family
RD05_RS00555	COG0321	lipoyl(octanoyl) transferase activity
RD05_RS00560	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
RD05_RS00595	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
RD05_RS00605	COG0018	arginyl-trna synthetase
RD05_RS00625	COG0395	ABC-type sugar transport system, permease component
RD05_RS00630	COG1175	transmembrane transport
RD05_RS00635	COG1653	transport
RD05_RS00640	COG3842	ATPase activity
RD05_RS00645	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
RD05_RS00720	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
RD05_RS00725	COG2816	NAD+ diphosphatase activity
RD05_RS00730	COG1309	transcriptional regulator
RD05_RS00735	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD05_RS00750	COG1024	Enoyl-CoA hydratase
RD05_RS00765	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RD05_RS00780	COG3181	Tripartite tricarboxylate transporter family receptor
RD05_RS00805	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RD05_RS00820	COG0220	tRNA (guanine-N7-)-methyltransferase activity
RD05_RS00835	COG1652	LysM domain
RD05_RS00845	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RD05_RS00850	COG1956	GAF domain-containing protein
RD05_RS00855	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RD05_RS00875	COG2186	Transcriptional regulator
RD05_RS00880	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
RD05_RS00905	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RD05_RS00925	COG0438	transferase activity, transferring glycosyl groups
RD05_RS00935	COG0402	S-adenosylhomocysteine deaminase activity
RD05_RS00975	COG0629	single-stranded DNA binding
RD05_RS00980	COG2814	Major facilitator Superfamily
RD05_RS00995	COG0232	Belongs to the dGTPase family. Type 2 subfamily
RD05_RS01000	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
RD05_RS01005	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
RD05_RS01015	COG1965	Belongs to the frataxin family
RD05_RS01025	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
RD05_RS01030	COG1333	cytochrome c biogenesis protein
RD05_RS01040	COG0218	Necessary for normal cell division and for the maintenance of normal septation
RD05_RS01055	COG4232	protein-disulfide reductase activity
RD05_RS01060	COG1324	tolerance protein
RD05_RS01065	COG0537	adenosine 5'-monophosphoramidase activity
RD05_RS01070	COG0203	ribosomal protein L17
RD05_RS01075	COG0202	RNA polymerase activity
RD05_RS01080	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
RD05_RS01085	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
RD05_RS01090	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
RD05_RS01095	COG0257	Belongs to the bacterial ribosomal protein bL36 family
RD05_RS01100	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
RD05_RS01105	COG0201	protein transport
RD05_RS01110	COG0200	Binds to the 23S rRNA
RD05_RS01115	COG1841	ribosomal large subunit assembly
RD05_RS01120	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
RD05_RS01125	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
RD05_RS01130	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
RD05_RS01135	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
RD05_RS01140	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
RD05_RS01145	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
RD05_RS01150	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
RD05_RS01155	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
RD05_RS01175	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
RD05_RS01180	COG0255	Belongs to the universal ribosomal protein uL29 family
RD05_RS01185	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
RD05_RS01190	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
RD05_RS01195	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
RD05_RS01200	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
RD05_RS01205	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
RD05_RS01210	COG0089	rRNA binding
RD05_RS01215	COG0088	Forms part of the polypeptide exit tunnel
RD05_RS01220	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
RD05_RS01225	COG0051	transcription antitermination factor activity, RNA binding
RD05_RS01230	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
RD05_RS01235	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
RD05_RS01240	COG0049	tRNA binding
RD05_RS01245	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
RD05_RS01255	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
RD05_RS01265	COG0628	permease
RD05_RS01275	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
RD05_RS01290	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
RD05_RS01295	COG0351	phosphomethylpyrimidine kinase
RD05_RS01300	COG2022	thiamine diphosphate biosynthetic process
RD05_RS01305	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RD05_RS01310	COG4206	TonB-dependent receptor
RD05_RS01330	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
RD05_RS01340	COG3781	membrane
RD05_RS01345	COG1522	sequence-specific DNA binding
RD05_RS01350	COG0028	Belongs to the TPP enzyme family
RD05_RS01360	COG1012	belongs to the aldehyde dehydrogenase family
RD05_RS01365	COG1028	Short-chain dehydrogenase reductase Sdr
RD05_RS01370	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RD05_RS01375	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
RD05_RS01400	COG2922	Belongs to the Smg family
RD05_RS01405	COG1629	transport
RD05_RS01415	COG2358	TRAP transporter, solute receptor (TAXI family
RD05_RS01425	COG3181	Tripartite tricarboxylate transporter family receptor
RD05_RS01430	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
RD05_RS01445	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
RD05_RS01450	COG0183	Belongs to the thiolase family
RD05_RS01460	COG1960	acyl-CoA dehydrogenase activity
RD05_RS01480	COG1960	acyl-CoA dehydrogenase activity
RD05_RS01500	COG1304	FMN binding
RD05_RS01515	COG0154	amidase activity
RD05_RS01520	COG1414	Transcriptional regulator
RD05_RS01535	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
RD05_RS01540	COG0230	Belongs to the bacterial ribosomal protein bL34 family
RD05_RS01545	COG0594	ribonuclease P activity
RD05_RS01550	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
RD05_RS01555	COG0706	membrane insertase activity
RD05_RS01565	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
RD05_RS01590	COG0582	viral genome integration into host DNA
RD05_RS01625	COG3723	Recombinational DNA repair protein, rece pathway
RD05_RS01670	COG0251	oxidation-reduction process
RD05_RS01680	COG0330	HflC and HflK could
RD05_RS01685	COG3422	double-strand break repair
RD05_RS01700	COG0583	DNA-binding transcription factor activity
RD05_RS01730	COG3181	Tripartite tricarboxylate transporter family receptor
RD05_RS01735	COG0318	PFAM AMP-dependent synthetase and ligase
RD05_RS01740	COG1414	Transcriptional regulator
RD05_RS01745	COG1024	Enoyl-CoA hydratase
RD05_RS01750	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RD05_RS01770	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
RD05_RS01790	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RD05_RS01795	COG1942	4-Oxalocrotonate Tautomerase
RD05_RS01800	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
RD05_RS01820	COG0546	phosphoglycolate phosphatase activity
RD05_RS01830	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
RD05_RS01840	COG0242	peptide deformylase activity
RD05_RS01850	COG1522	sequence-specific DNA binding
RD05_RS01855	COG0758	DNA mediated transformation
RD05_RS01870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RD05_RS01875	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RD05_RS01880	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
RD05_RS01895	COG0583	DNA-binding transcription factor activity
RD05_RS01920	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
RD05_RS01930	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
RD05_RS01930	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
RD05_RS01940	COG5000	phosphorelay sensor kinase activity
RD05_RS01945	COG2204	response regulator
RD05_RS01970	COG2068	MobA-Related Protein
RD05_RS01980	COG3473	Maleate cis-trans isomerase
RD05_RS01985	COG0596	Alpha beta hydrolase
RD05_RS01990	COG2309	aminopeptidase activity
RD05_RS01995	COG1335	isochorismatase
RD05_RS02020	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
RD05_RS02045	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
RD05_RS02050	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RD05_RS02065	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
RD05_RS02070	COG2226	methyltransferase
RD05_RS02085	COG3181	Tripartite tricarboxylate transporter family receptor
RD05_RS02090	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
RD05_RS02095	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
RD05_RS02100	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
RD05_RS02105	COG1054	Belongs to the UPF0176 family
RD05_RS02110	COG0588	phosphoglycerate mutase activity
RD05_RS02115	COG4942	peptidase
RD05_RS02120	COG0793	Belongs to the peptidase S41A family
RD05_RS02125	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
RD05_RS02150	COG3181	Tripartite tricarboxylate transporter family receptor
RD05_RS02165	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RD05_RS02175	COG0411	ABC transporter
RD05_RS02180	COG0559	Belongs to the binding-protein-dependent transport system permease family
RD05_RS02185	COG0683	leucine binding
RD05_RS02205	COG0508	dehydrogenase complex catalyzes the overall conversion of
RD05_RS02210	COG1024	Enoyl-CoA hydratase
RD05_RS02215	COG0022	dehydrogenase e1 component
RD05_RS02220	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
RD05_RS02240	COG1960	acyl-CoA dehydrogenase activity
RD05_RS02245	COG1024	Enoyl-CoA hydratase
RD05_RS02250	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
RD05_RS02270	COG1960	acyl-CoA dehydrogenase activity
RD05_RS02275	COG3181	Tripartite tricarboxylate transporter family receptor
RD05_RS02280	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD05_RS02290	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RD05_RS02310	COG3181	Tripartite tricarboxylate transporter family receptor
RD05_RS02320	COG0277	FAD linked oxidase domain protein
RD05_RS02325	COG1960	acyl-CoA dehydrogenase activity
RD05_RS02330	COG1960	acyl-CoA dehydrogenase activity
RD05_RS02340	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RD05_RS02360	COG0604	alcohol dehydrogenase
RD05_RS02375	COG1024	Enoyl-CoA hydratase
RD05_RS02395	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
RD05_RS02400	COG1522	sequence-specific DNA binding
RD05_RS02405	COG0183	Belongs to the thiolase family
RD05_RS02415	COG1960	acyl-CoA dehydrogenase activity
RD05_RS02460	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
RD05_RS02465	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
RD05_RS02470	COG2890	protein-(glutamine-N5) methyltransferase activity
RD05_RS02475	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
RD05_RS02485	COG3181	Tripartite tricarboxylate transporter family receptor
RD05_RS02525	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
RD05_RS02530	COG1660	Displays ATPase and GTPase activities
RD05_RS02540	COG1529	Aldehyde oxidase and xanthine dehydrogenase
RD05_RS02540	COG2010	Cytochrome c
RD05_RS02545	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
RD05_RS02555	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
RD05_RS02560	COG1137	ATPase activity
RD05_RS02575	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
RD05_RS02585	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
RD05_RS02620	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
RD05_RS02625	COG3568	Endonuclease Exonuclease Phosphatase
RD05_RS02630	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RD05_RS02660	COG0154	amidase activity
RD05_RS02670	COG1414	Transcriptional regulator
RD05_RS02685	COG1024	Enoyl-CoA hydratase
RD05_RS02685	COG1250	3-hydroxyacyl-CoA dehydrogenase
RD05_RS02695	COG2132	Multicopper oxidase
RD05_RS02725	COG1250	3-hydroxyacyl-CoA dehydrogenase
RD05_RS02750	COG1024	Enoyl-CoA hydratase
RD05_RS02755	COG1024	Enoyl-CoA hydratase
RD05_RS02760	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
RD05_RS02780	COG0601	transmembrane transport
RD05_RS02785	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RD05_RS02790	COG4608	Belongs to the ABC transporter superfamily
RD05_RS02800	COG2195	Cleaves the N-terminal amino acid of tripeptides
RD05_RS02810	COG0210	DNA helicase
RD05_RS02815	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
RD05_RS02820	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
RD05_RS02830	COG0355	proton-transporting ATP synthase activity, rotational mechanism
RD05_RS02835	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
RD05_RS02840	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
RD05_RS02845	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
RD05_RS02850	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
RD05_RS02855	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
RD05_RS02865	COG0356	it plays a direct role in the translocation of protons across the membrane
RD05_RS02890	COG1024	Enoyl-CoA hydratase
RD05_RS02895	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RD05_RS02900	COG3634	alkyl hydroperoxide reductase activity
RD05_RS02910	COG0037	tRNA processing
RD05_RS02920	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RD05_RS02925	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
RD05_RS02930	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RD05_RS02935	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
RD05_RS02940	COG2967	ApaG domain
RD05_RS02945	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
RD05_RS02950	COG0546	phosphoglycolate phosphatase activity
RD05_RS02960	COG0512	Glutamine amidotransferase of anthranilate synthase
RD05_RS02965	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
RD05_RS02970	COG0134	indole-3-glycerol-phosphate synthase activity
RD05_RS02995	COG1960	acyl-CoA dehydrogenase activity
RD05_RS03000	COG0583	DNA-binding transcription factor activity
RD05_RS03015	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RD05_RS03020	COG0259	pyridoxamine-phosphate oxidase activity
RD05_RS03030	COG2814	Major facilitator Superfamily
RD05_RS03035	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
RD05_RS03040	COG2188	Transcriptional regulator
RD05_RS03045	COG0318	PFAM AMP-dependent synthetase and ligase
RD05_RS03065	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
RD05_RS03075	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
RD05_RS03090	COG1215	transferase activity, transferring glycosyl groups
RD05_RS03100	COG0601	transmembrane transport
RD05_RS03110	COG0488	(ABC) transporter
RD05_RS03130	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
RD05_RS03135	COG2894	cell division
RD05_RS03140	COG0850	regulation of cytokinetic process
RD05_RS03145	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
RD05_RS03150	COG1271	oxidase subunit
RD05_RS03185	COG2979	Protein of unknown function (DUF533)
RD05_RS03205	COG1388	LysM domain
RD05_RS03205	COG0741	lytic transglycosylase activity
RD05_RS03210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RD05_RS03215	COG2226	methyltransferase
RD05_RS03220	COG0328	RNA-DNA hybrid ribonuclease activity
RD05_RS03265	COG2030	dehydratase
RD05_RS03270	COG0183	Belongs to the thiolase family
RD05_RS03315	COG1960	acyl-CoA dehydrogenase activity
RD05_RS03330	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD05_RS03335	COG1028	Short-chain dehydrogenase reductase Sdr
RD05_RS03350	COG2718	Belongs to the UPF0229 family
RD05_RS03355	COG2719	SpoVR family
RD05_RS03380	COG2188	Transcriptional regulator
RD05_RS03395	COG0633	Ferredoxin
RD05_RS03405	COG0829	nickel cation binding
RD05_RS03410	COG0831	urea catabolic process
RD05_RS03420	COG0832	Belongs to the urease beta subunit family
RD05_RS03425	COG0804	urea catabolic process
RD05_RS03435	COG0830	nickel cation binding
RD05_RS03440	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
RD05_RS03460	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RD05_RS03465	COG0601	transmembrane transport
RD05_RS03470	COG0747	negative chemotaxis
RD05_RS03480	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
RD05_RS03485	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RD05_RS03495	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
RD05_RS03505	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
RD05_RS03510	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
RD05_RS03515	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
RD05_RS03530	COG0438	transferase activity, transferring glycosyl groups
RD05_RS03550	COG0438	transferase activity, transferring glycosyl groups
RD05_RS03555	COG0166	Belongs to the GPI family
RD05_RS03570	COG0277	FAD linked oxidase domain protein
RD05_RS03575	COG0745	RESPONSE REGULATOR receiver
RD05_RS03580	COG0642	Histidine kinase
RD05_RS03585	COG1368	sulfuric ester hydrolase activity
RD05_RS03595	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
RD05_RS03620	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
RD05_RS03630	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
RD05_RS03635	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
RD05_RS03645	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
RD05_RS03650	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
RD05_RS03655	COG0193	aminoacyl-tRNA hydrolase activity
RD05_RS03665	COG0012	GTP binding
RD05_RS03670	COG0582	viral genome integration into host DNA
RD05_RS03690	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
RD05_RS03740	COG0745	RESPONSE REGULATOR receiver
RD05_RS03755	COG1309	transcriptional regulator
RD05_RS03780	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RD05_RS03790	COG0405	Gamma-glutamyltransferase
RD05_RS03805	COG1280	lysine exporter protein (LysE YggA)
RD05_RS03865	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
RD05_RS03870	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RD05_RS03880	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
RD05_RS03885	COG0513	Belongs to the DEAD box helicase family
RD05_RS03895	COG0617	tRNA 3'-terminal CCA addition
RD05_RS03910	COG0477	Major facilitator Superfamily
RD05_RS03920	COG0583	DNA-binding transcription factor activity
RD05_RS03935	COG1950	PFAM Membrane protein of
RD05_RS03940	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
RD05_RS03955	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
RD05_RS03965	COG1560	Kdo2-lipid A biosynthetic process
RD05_RS03970	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
RD05_RS03980	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
RD05_RS03990	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
RD05_RS04000	COG0803	Belongs to the bacterial solute-binding protein 9 family
RD05_RS04020	COG0735	belongs to the Fur family
RD05_RS04025	COG0523	cobalamin synthesis protein
RD05_RS04035	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
RD05_RS04040	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
RD05_RS04050	COG2096	Adenosyltransferase
RD05_RS04065	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
RD05_RS04070	COG2084	Dehydrogenase
RD05_RS04125	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
RD05_RS04130	COG0129	dihydroxy-acid dehydratase activity
RD05_RS04135	COG4654	Cytochrome c, class I
RD05_RS04140	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
RD05_RS04190	COG1473	amidohydrolase
RD05_RS04195	COG0418	dihydroorotase activity
RD05_RS04200	COG0488	(ABC) transporter
RD05_RS04210	COG2001	Belongs to the MraZ family
RD05_RS04215	COG0275	rRNA processing
RD05_RS04220	COG3116	cell division
RD05_RS04230	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
RD05_RS04235	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
RD05_RS04240	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
RD05_RS04250	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
RD05_RS04255	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
RD05_RS04260	COG1181	Belongs to the D-alanine--D-alanine ligase family
RD05_RS04265	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
RD05_RS04275	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
RD05_RS04280	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
RD05_RS04290	COG0739	heme binding
RD05_RS04295	COG0653	protein targeting
RD05_RS04315	COG1028	Short-chain dehydrogenase reductase Sdr
RD05_RS04320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RD05_RS04325	COG1522	sequence-specific DNA binding
RD05_RS04345	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
RD05_RS04355	COG0557	exoribonuclease II activity
RD05_RS04360	COG3150	esterase
RD05_RS04365	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
RD05_RS04370	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RD05_RS04375	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
RD05_RS04380	COG0511	ligase activity, forming carbon-carbon bonds
RD05_RS04385	COG0439	Biotin carboxylase
RD05_RS04390	COG2264	protein methyltransferase activity
RD05_RS04400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RD05_RS04425	COG1696	Membrane protein involved in D-alanine export
RD05_RS04430	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RD05_RS04465	COG1522	sequence-specific DNA binding
RD05_RS04480	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
RD05_RS04485	COG0045	succinate-CoA ligase (ADP-forming) activity
RD05_RS04485	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RD05_RS04485	COG1042	CoA-binding domain protein
RD05_RS04495	COG1802	Transcriptional regulator
RD05_RS04500	COG3069	C4-dicarboxylate transmembrane transporter activity
RD05_RS04505	COG0513	Belongs to the DEAD box helicase family
RD05_RS04510	COG0346	lactoylglutathione lyase activity
RD05_RS04515	COG1335	isochorismatase
RD05_RS04520	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RD05_RS04525	COG1116	anion transmembrane transporter activity
RD05_RS04540	COG3028	Belongs to the UPF0307 family
RD05_RS04545	COG0312	modulator of DNA gyrase
RD05_RS04550	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
RD05_RS04555	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
RD05_RS04560	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
RD05_RS04565	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
RD05_RS04575	COG0316	Belongs to the HesB IscA family
RD05_RS04580	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
RD05_RS04595	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
RD05_RS04605	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
RD05_RS04610	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
RD05_RS04625	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
RD05_RS04625	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
RD05_RS04655	COG0583	DNA-binding transcription factor activity
RD05_RS04660	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD05_RS04695	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
RD05_RS04705	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
RD05_RS04710	COG1845	cytochrome c oxidase, subunit III
RD05_RS04715	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
RD05_RS04720	COG0640	Transcriptional regulator
RD05_RS04740	COG3220	belongs to the UPF0276 family
RD05_RS04785	COG1666	GTP binding
RD05_RS04820	COG0312	modulator of DNA gyrase
RD05_RS04825	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
RD05_RS04830	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
RD05_RS04830	COG3210	domain, Protein
RD05_RS04830	COG3064	Membrane
RD05_RS04830	COG3210	domain, Protein
RD05_RS04830	COG3064	Membrane
RD05_RS04830	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
RD05_RS04835	COG0277	FAD linked oxidase domain protein
RD05_RS04840	COG0277	FAD linked oxidase domain protein
RD05_RS04845	COG0277	FAD linked oxidase domain protein
RD05_RS04850	COG0247	lactate metabolic process
RD05_RS04855	COG2819	hydrolase of the alpha beta superfamily
RD05_RS04890	COG0583	DNA-binding transcription factor activity
RD05_RS04895	COG0482	sulfurtransferase activity
RD05_RS04900	COG0730	response to heat
RD05_RS04905	COG0625	glutathione transferase activity
RD05_RS04910	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
RD05_RS04915	COG3909	cytochrome
RD05_RS04955	COG0154	amidase activity
RD05_RS04960	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD05_RS04965	COG1024	Enoyl-CoA hydratase
RD05_RS04980	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RD05_RS04995	COG1028	Short-chain dehydrogenase reductase Sdr
RD05_RS05000	COG1414	Transcriptional regulator
RD05_RS05010	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RD05_RS05015	COG0251	oxidation-reduction process
RD05_RS05020	COG0559	Belongs to the binding-protein-dependent transport system permease family
RD05_RS05040	COG1902	pentaerythritol trinitrate reductase activity
RD05_RS05055	COG0583	DNA-binding transcription factor activity
RD05_RS05065	COG0590	tRNA wobble adenosine to inosine editing
RD05_RS05070	COG2807	transmembrane transport
RD05_RS05090	COG0154	amidase activity
RD05_RS05095	COG0307	riboflavin synthase, alpha
RD05_RS05100	COG3181	Tripartite tricarboxylate transporter family receptor
RD05_RS05105	COG1522	sequence-specific DNA binding
RD05_RS05115	COG0318	PFAM AMP-dependent synthetase and ligase
RD05_RS05125	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RD05_RS05145	COG1063	alcohol dehydrogenase
RD05_RS05170	COG1418	mRNA catabolic process
RD05_RS05175	COG1448	Aminotransferase
RD05_RS05180	COG0583	DNA-binding transcription factor activity
RD05_RS05190	COG0477	Major facilitator Superfamily
RD05_RS05195	COG1028	Short-chain dehydrogenase reductase Sdr
RD05_RS05210	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
RD05_RS05215	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
RD05_RS05220	COG0583	DNA-binding transcription factor activity
RD05_RS05260	COG1028	Short-chain dehydrogenase reductase Sdr
RD05_RS05265	COG1309	transcriptional regulator
RD05_RS05275	COG2982	Protein involved in outer membrane biogenesis
RD05_RS05280	COG2818	Glycosylase
RD05_RS05300	COG1653	transport
RD05_RS05310	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RD05_RS05315	COG3842	ATPase activity
RD05_RS05320	COG0395	ABC-type sugar transport system, permease component
RD05_RS05325	COG1175	transmembrane transport
RD05_RS05345	COG3181	Tripartite tricarboxylate transporter family receptor
RD05_RS05350	COG2186	Transcriptional regulator
RD05_RS05375	COG1454	alcohol dehydrogenase
RD05_RS05395	COG2011	ABC-type metal ion transport system permease component
RD05_RS05400	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
RD05_RS05405	COG1501	Belongs to the glycosyl hydrolase 31 family
RD05_RS05425	COG0318	PFAM AMP-dependent synthetase and ligase
RD05_RS05430	COG1473	amidohydrolase
RD05_RS05440	COG2855	membrane
RD05_RS05450	COG2239	Acts as a magnesium transporter
RD05_RS05470	COG3181	Tripartite tricarboxylate transporter family receptor
RD05_RS05480	COG1722	exodeoxyribonuclease VII activity
RD05_RS05485	COG0142	geranyltranstransferase activity
RD05_RS05490	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
RD05_RS05495	COG1469	GTP cyclohydrolase I activity
RD05_RS05500	COG0360	Binds together with S18 to 16S ribosomal RNA
RD05_RS05505	COG2965	DNA replication, synthesis of RNA primer
RD05_RS05510	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
RD05_RS05515	COG0359	binds to the 23S rRNA
RD05_RS05525	COG0305	Participates in initiation and elongation during chromosome replication
RD05_RS05535	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
RD05_RS05540	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
RD05_RS05545	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
RD05_RS05550	COG3737	Protein of unknown function (DUF498/DUF598)
RD05_RS05555	COG0436	Aminotransferase
RD05_RS05580	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
RD05_RS05610	COG0268	Binds directly to 16S ribosomal RNA
RD05_RS05620	COG0728	peptidoglycan biosynthetic process
RD05_RS05630	COG0563	adenylate kinase activity
RD05_RS05635	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
RD05_RS05640	COG2835	tetraacyldisaccharide 4'-kinase activity
RD05_RS05645	COG1663	tetraacyldisaccharide 4'-kinase activity
RD05_RS05650	COG0848	biopolymer transport protein
RD05_RS05655	COG0811	peptide transport
RD05_RS05665	COG1570	exodeoxyribonuclease VII activity
RD05_RS05670	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
RD05_RS05675	COG0038	chloride channel
RD05_RS05680	COG0183	Belongs to the thiolase family
RD05_RS05690	COG1278	Cold shock
RD05_RS05695	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
RD05_RS05705	COG4953	penicillin-binding protein 1C
RD05_RS05710	COG0542	response to heat
RD05_RS05715	COG2995	paraquat-inducible protein a
RD05_RS05720	COG3008	intermembrane lipid transfer
RD05_RS05720	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
RD05_RS05730	COG0506	proline dehydrogenase activity
RD05_RS05730	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
RD05_RS05730	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
RD05_RS05765	COG2271	Major facilitator Superfamily
RD05_RS05770	COG1309	transcriptional regulator
RD05_RS05780	COG3468	outer membrane autotransporter barrel domain protein
RD05_RS05810	COG0477	Major facilitator Superfamily
RD05_RS05820	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
RD05_RS05825	COG1845	cytochrome c oxidase, subunit III
RD05_RS05830	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
RD05_RS05840	COG1028	Short-chain dehydrogenase reductase Sdr
RD05_RS05860	COG0789	Transcriptional regulator
RD05_RS05885	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
RD05_RS05890	COG0697	spore germination
RD05_RS05900	COG0678	peroxiredoxin activity
RD05_RS05910	COG0412	Dienelactone hydrolase
RD05_RS05920	COG0315	cyclic pyranopterin monophosphate synthase activity
RD05_RS05935	COG0521	Mo-molybdopterin cofactor biosynthetic process
RD05_RS05940	COG0303	'Molybdopterin
RD05_RS05945	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
RD05_RS05965	COG0165	Argininosuccinate lyase
RD05_RS05970	COG0668	transmembrane transport
RD05_RS06015	COG0747	negative chemotaxis
RD05_RS06020	COG0601	transmembrane transport
RD05_RS06025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RD05_RS06030	COG1162	GTPase activity
RD05_RS06035	COG0501	Belongs to the peptidase M48B family
RD05_RS06040	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
RD05_RS06050	COG3327	negative regulation of DNA-templated transcription, initiation
RD05_RS06055	COG3396	Phenylacetate-CoA oxygenase
RD05_RS06060	COG3460	Phenylacetate-CoA oxygenase
RD05_RS06065	COG3396	Phenylacetate-CoA oxygenase
RD05_RS06070	COG2151	metal-sulfur cluster biosynthetic enzyme
RD05_RS06075	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
RD05_RS06085	COG1012	belongs to the aldehyde dehydrogenase family
RD05_RS06090	COG1024	Enoyl-CoA hydratase
RD05_RS06095	COG2050	protein possibly involved in aromatic compounds catabolism
RD05_RS06105	COG3539	Fimbrial protein
RD05_RS06120	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
RD05_RS06125	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
RD05_RS06125	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
RD05_RS06130	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
RD05_RS06135	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
RD05_RS06135	COG0047	phosphoribosylformylglycinamidine synthase activity
RD05_RS06140	COG3064	Membrane
RD05_RS06140	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
RD05_RS06140	COG3210	domain, Protein
RD05_RS06165	COG0235	Class ii aldolase
RD05_RS06170	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
RD05_RS06175	COG0720	synthase
RD05_RS06180	COG0602	queuosine metabolic process
RD05_RS06205	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RD05_RS06240	COG3181	Tripartite tricarboxylate transporter family receptor
RD05_RS06270	COG3842	ATPase activity
RD05_RS06280	COG0395	ABC-type sugar transport system, permease component
RD05_RS06310	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RD05_RS06315	COG0420	3'-5' exonuclease activity
RD05_RS06340	COG2197	response regulator
RD05_RS06365	COG0519	Catalyzes the synthesis of GMP from XMP
RD05_RS06365	COG0518	GMP synthase (glutamine-hydrolyzing) activity
RD05_RS06375	COG3550	peptidyl-serine autophosphorylation
RD05_RS06385	COG0477	Major facilitator Superfamily
RD05_RS06400	COG1228	amidohydrolase
RD05_RS06410	COG1116	anion transmembrane transporter activity
RD05_RS06415	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RD05_RS06450	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
RD05_RS06465	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
RD05_RS06495	COG2814	Major facilitator Superfamily
RD05_RS06510	COG1280	lysine exporter protein (LysE YggA)
RD05_RS06525	COG0747	negative chemotaxis
RD05_RS06530	COG0601	transmembrane transport
RD05_RS06535	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RD05_RS06540	COG4172	Belongs to the ABC transporter superfamily
RD05_RS06545	COG1609	Transcriptional regulator
RD05_RS06570	COG0586	Pfam SNARE associated Golgi protein
RD05_RS06580	COG0500	methyltransferase
RD05_RS06595	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RD05_RS06605	COG0756	dUTP diphosphatase activity
RD05_RS06615	COG0291	Belongs to the bacterial ribosomal protein bL35 family
RD05_RS06620	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
RD05_RS06625	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
RD05_RS06630	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RD05_RS06630	COG0072	phenylalanine-tRNA ligase activity
RD05_RS06635	COG0776	regulation of translation
RD05_RS06705	COG0540	Belongs to the ATCase OTCase family
RD05_RS06710	COG2974	May be involved in recombination
RD05_RS06720	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD05_RS06725	COG0583	DNA-binding transcription factor activity
RD05_RS06745	COG1028	Short-chain dehydrogenase reductase Sdr
RD05_RS06760	COG3842	ATPase activity
RD05_RS06765	COG1250	3-hydroxyacyl-CoA dehydrogenase
RD05_RS06765	COG1024	Enoyl-CoA hydratase
RD05_RS06785	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
RD05_RS06790	COG2137	regulation of response to DNA damage stimulus
RD05_RS06800	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
RD05_RS06810	COG0045	succinate-CoA ligase (ADP-forming) activity
RD05_RS06815	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
RD05_RS06820	COG0861	Integral membrane protein TerC family
RD05_RS06825	COG0861	Integral membrane protein TerC family
RD05_RS06830	COG0181	hydroxymethylbilane synthase activity
RD05_RS06890	COG4964	Belongs to the GSP D family
RD05_RS06920	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
RD05_RS06930	COG0583	DNA-binding transcription factor activity
RD05_RS06940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RD05_RS06945	COG4311	Sarcosine oxidase, delta subunit
RD05_RS06950	COG0446	pyridine nucleotide-disulphide oxidoreductase
RD05_RS06950	COG0404	The glycine cleavage system catalyzes the degradation of glycine
RD05_RS06985	COG0812	UDP-N-acetylmuramate dehydrogenase activity
RD05_RS06990	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
RD05_RS06995	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
RD05_RS07000	COG0735	belongs to the Fur family
RD05_RS07005	COG0497	DNA recombination
RD05_RS07010	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
RD05_RS07015	COG1420	regulation of RNA biosynthetic process
RD05_RS07020	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
RD05_RS07030	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
RD05_RS07040	COG0443	Heat shock 70 kDa protein
RD05_RS07050	COG0612	Peptidase, M16
RD05_RS07070	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
RD05_RS07115	COG0745	RESPONSE REGULATOR receiver
RD05_RS07120	COG2205	protein histidine kinase activity
RD05_RS07125	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
RD05_RS07130	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
RD05_RS07135	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
RD05_RS07145	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RD05_RS07165	COG1193	negative regulation of DNA recombination
RD05_RS07170	COG0492	ferredoxin-NADP+ reductase activity
RD05_RS07175	COG1674	ftsk spoiiie
RD05_RS07180	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
RD05_RS07185	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
RD05_RS07190	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
RD05_RS07215	COG3706	GGDEF domain
RD05_RS07235	COG2814	Major facilitator Superfamily
RD05_RS07265	COG3486	L-lysine 6-monooxygenase (NADPH) activity
RD05_RS07280	COG1028	Short-chain dehydrogenase reductase Sdr
RD05_RS07290	COG3022	response to hydroperoxide
RD05_RS07300	COG1289	transmembrane transporter activity
RD05_RS07320	COG0635	Involved in the biosynthesis of porphyrin-containing compound
RD05_RS07330	COG2197	response regulator
RD05_RS07335	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
RD05_RS07340	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
RD05_RS07345	COG0189	ligase activity
RD05_RS07355	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
RD05_RS07360	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
RD05_RS07370	COG2423	ornithine cyclodeaminase activity
RD05_RS07380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RD05_RS07385	COG0765	amino acid transport
RD05_RS07390	COG0765	amino acid transport
RD05_RS07395	COG1126	abc transporter atp-binding protein
RD05_RS07450	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
RD05_RS07460	COG2944	sequence-specific DNA binding
RD05_RS07465	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
RD05_RS07470	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
RD05_RS07475	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
RD05_RS07480	COG0009	L-threonylcarbamoyladenylate synthase
RD05_RS07485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RD05_RS07490	COG1414	Transcriptional regulator
RD05_RS07505	COG0765	amino acid transport
RD05_RS07510	COG1126	abc transporter atp-binding protein
RD05_RS07515	COG0028	Belongs to the TPP enzyme family
RD05_RS07530	COG0028	Belongs to the TPP enzyme family
RD05_RS07535	COG0583	DNA-binding transcription factor activity
RD05_RS07540	COG4974	Belongs to the 'phage' integrase family
RD05_RS07545	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
RD05_RS07550	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
RD05_RS07565	COG1686	Belongs to the peptidase S11 family
RD05_RS07575	COG2814	Major facilitator Superfamily
RD05_RS07585	COG1074	ATP-dependent DNA helicase activity
RD05_RS07595	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
RD05_RS07600	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
RD05_RS07605	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
RD05_RS07625	COG2321	neutral zinc metallopeptidase
RD05_RS07630	COG0009	L-threonylcarbamoyladenylate synthase
RD05_RS07670	COG3360	Dodecin
RD05_RS07675	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
RD05_RS07680	COG2850	peptidyl-arginine hydroxylation
RD05_RS07685	COG3539	Fimbrial protein
RD05_RS07690	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
RD05_RS07695	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RD05_RS07700	COG1994	Peptidase M50
RD05_RS07710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RD05_RS07715	COG0765	amino acid transport
RD05_RS07720	COG1126	abc transporter atp-binding protein
RD05_RS07725	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
RD05_RS07730	COG1758	RNA polymerase activity
RD05_RS07735	COG0194	GDP metabolic process
RD05_RS07740	COG3258	Cytochrome c
RD05_RS07745	COG2863	cytochrome
RD05_RS07750	COG1028	Short-chain dehydrogenase reductase Sdr
RD05_RS07755	COG0791	NLP P60 protein
RD05_RS07760	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
RD05_RS07780	COG1561	YicC-like family, N-terminal region
RD05_RS07785	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
RD05_RS07800	COG2200	EAL domain
RD05_RS07800	COG2199	diguanylate cyclase activity
RD05_RS07805	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
RD05_RS07815	COG0635	Involved in the biosynthesis of porphyrin-containing compound
RD05_RS07820	COG0174	glutamine synthetase
RD05_RS07830	COG2204	response regulator
RD05_RS07835	COG0583	DNA-binding transcription factor activity
RD05_RS07840	COG1741	Belongs to the pirin family
RD05_RS07845	COG1741	Belongs to the pirin family
RD05_RS07855	COG3842	ATPase activity
RD05_RS07860	COG1178	ABC-type Fe3 transport system permease component
RD05_RS07865	COG1840	ABC-type Fe3 transport system, periplasmic component
RD05_RS07875	COG0583	DNA-binding transcription factor activity
RD05_RS07885	COG0656	L-ascorbic acid biosynthetic process
RD05_RS07900	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
RD05_RS07905	COG0583	DNA-binding transcription factor activity
RD05_RS07920	COG0783	Belongs to the Dps family
RD05_RS07955	COG0438	transferase activity, transferring glycosyl groups
RD05_RS07970	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
RD05_RS07995	COG0300	oxidoreductase activity
RD05_RS08040	COG0861	Integral membrane protein TerC family
RD05_RS08045	COG1028	Short-chain dehydrogenase reductase Sdr
RD05_RS08065	COG0714	Associated with various cellular activities
RD05_RS08095	COG3119	arylsulfatase activity
RD05_RS08120	COG2197	response regulator
RD05_RS08130	COG2944	sequence-specific DNA binding
RD05_RS08135	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
RD05_RS08140	COG0625	glutathione transferase activity
RD05_RS08170	COG0179	Fumarylacetoacetate (FAA) hydrolase
RD05_RS08175	COG1028	Short-chain dehydrogenase reductase Sdr
RD05_RS08220	COG0431	NADPH-dependent FMN reductase
RD05_RS08250	COG1028	Short-chain dehydrogenase reductase Sdr
RD05_RS08255	COG0583	DNA-binding transcription factor activity
RD05_RS08270	COG3181	Tripartite tricarboxylate transporter family receptor
RD05_RS08275	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
RD05_RS08275	COG2111	Na H antiporter
RD05_RS08280	COG1006	Multisubunit Na H antiporter MnhC subunit
RD05_RS08285	COG0651	ATP synthesis coupled electron transport
RD05_RS08290	COG1863	multisubunit Na H antiporter MnhE subunit
RD05_RS08295	COG2212	antiporter activity
RD05_RS08320	COG0590	tRNA wobble adenosine to inosine editing
RD05_RS08325	COG1619	proteins homologs of microcin C7 resistance protein MccF
RD05_RS08330	COG1024	Enoyl-CoA hydratase
RD05_RS08345	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
RD05_RS08350	COG0488	(ABC) transporter
RD05_RS08390	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
RD05_RS08390	COG1017	nitric oxide dioxygenase activity
RD05_RS08395	COG1959	2 iron, 2 sulfur cluster binding
RD05_RS08400	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RD05_RS08420	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
RD05_RS08425	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
RD05_RS08430	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
RD05_RS08435	COG0084	hydrolase, TatD family'
RD05_RS08450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RD05_RS08460	COG1126	abc transporter atp-binding protein
RD05_RS08465	COG0010	Belongs to the arginase family
RD05_RS08470	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
RD05_RS08475	COG1012	belongs to the aldehyde dehydrogenase family
RD05_RS08485	COG0028	Belongs to the TPP enzyme family
RD05_RS08495	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
RD05_RS08495	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
RD05_RS08505	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
RD05_RS08520	COG3189	MarR family transcriptional regulator
RD05_RS08545	COG4336	lyase activity
RD05_RS08555	COG2205	protein histidine kinase activity
RD05_RS08555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RD05_RS08560	COG2197	response regulator
RD05_RS08565	COG3210	domain, Protein
RD05_RS08565	COG3064	Membrane
RD05_RS08565	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
RD05_RS08575	COG3121	Chaperone
RD05_RS08580	COG3188	usher protein
RD05_RS08585	COG3539	Fimbrial protein
RD05_RS08590	COG2831	hemolysin activation secretion protein
RD05_RS08605	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
RD05_RS08630	COG0583	DNA-binding transcription factor activity
RD05_RS08655	COG0668	transmembrane transport
RD05_RS08675	COG0483	inositol monophosphate 1-phosphatase activity
RD05_RS08680	COG1253	flavin adenine dinucleotide binding
RD05_RS08685	COG1968	undecaprenyl-diphosphatase activity
RD05_RS08690	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
RD05_RS08705	COG0215	cysteine-tRNA ligase activity
RD05_RS08715	COG0825	malonyl-CoA metabolic process
RD05_RS08725	COG0037	tRNA processing
RD05_RS08730	COG0527	aspartate kinase activity
RD05_RS08755	COG1250	3-hydroxyacyl-CoA dehydrogenase
RD05_RS08760	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
RD05_RS08760	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
RD05_RS08775	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
RD05_RS08780	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
RD05_RS08785	COG1028	Short-chain dehydrogenase reductase Sdr
RD05_RS08795	COG0583	DNA-binding transcription factor activity
RD05_RS08825	COG3842	ATPase activity
RD05_RS08835	COG0446	pyridine nucleotide-disulphide oxidoreductase
RD05_RS08835	COG1902	pentaerythritol trinitrate reductase activity
RD05_RS08840	COG1414	Transcriptional regulator
RD05_RS08845	COG1832	CoA-binding protein
RD05_RS08855	COG0251	oxidation-reduction process
RD05_RS08880	COG1902	pentaerythritol trinitrate reductase activity
RD05_RS08890	COG1215	transferase activity, transferring glycosyl groups
RD05_RS08895	COG1649	PFAM Uncharacterised BCR, COG1649
RD05_RS08895	COG0726	polysaccharide deacetylase
RD05_RS08915	COG1846	Transcriptional regulator
RD05_RS08935	COG0166	Belongs to the GPI family
RD05_RS08940	COG1045	serine acetyltransferase
RD05_RS08950	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
RD05_RS08955	COG0483	inositol monophosphate 1-phosphatase activity
RD05_RS08960	COG1012	belongs to the aldehyde dehydrogenase family
RD05_RS08965	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
RD05_RS08980	COG0210	DNA helicase
RD05_RS08985	COG0598	Magnesium transport protein CorA
RD05_RS08995	COG0747	negative chemotaxis
RD05_RS09000	COG0601	transmembrane transport
RD05_RS09005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RD05_RS09010	COG4172	Belongs to the ABC transporter superfamily
RD05_RS09015	COG1846	Transcriptional regulator
RD05_RS09065	COG4964	Belongs to the GSP D family
RD05_RS09105	COG2204	response regulator
RD05_RS09120	COG1595	DNA-templated transcription, initiation
RD05_RS09130	COG3474	cytochrome
RD05_RS09135	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
RD05_RS09150	COG3384	dioxygenase
RD05_RS09155	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
RD05_RS09180	COG2885	chlorophyll binding
RD05_RS09215	COG0697	spore germination
RD05_RS09220	COG0730	response to heat
RD05_RS09235	COG0583	DNA-binding transcription factor activity
RD05_RS09240	COG0427	acetyl-CoA hydrolase
RD05_RS09295	COG1250	3-hydroxyacyl-CoA dehydrogenase
RD05_RS09300	COG0154	amidase activity
RD05_RS09310	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
RD05_RS09325	COG0495	leucyl-tRNA aminoacylation
RD05_RS09330	COG2814	Major facilitator Superfamily
RD05_RS09360	COG0267	Belongs to the bacterial ribosomal protein bL33 family
RD05_RS09365	COG0227	Belongs to the bacterial ribosomal protein bL28 family
RD05_RS09370	COG2814	Major facilitator Superfamily
RD05_RS09375	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
RD05_RS09390	COG4176	ABC-type proline glycine betaine transport system permease component
RD05_RS09400	COG1942	4-Oxalocrotonate Tautomerase
RD05_RS09405	COG0183	Belongs to the thiolase family
RD05_RS09415	COG1802	Transcriptional regulator
RD05_RS09425	COG1024	Enoyl-CoA hydratase
RD05_RS09440	COG2032	superoxide dismutase activity
RD05_RS09455	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
RD05_RS09480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RD05_RS09485	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RD05_RS09495	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
RD05_RS09500	COG0736	holo-[acyl-carrier-protein] synthase activity
RD05_RS09505	COG1472	Belongs to the glycosyl hydrolase 3 family
RD05_RS09510	COG0322	excinuclease ABC activity
RD05_RS09515	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
RD05_RS09530	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
RD05_RS09530	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
RD05_RS09535	COG2224	Isocitrate lyase
RD05_RS09555	COG0559	Belongs to the binding-protein-dependent transport system permease family
RD05_RS09565	COG4638	Rieske (2fe-2S)
RD05_RS09575	COG1024	Enoyl-CoA hydratase
RD05_RS09585	COG0633	Ferredoxin
RD05_RS09590	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD05_RS09605	COG0183	Belongs to the thiolase family
RD05_RS09615	COG4692	amylo-alpha-1,6-glucosidase activity
RD05_RS09620	COG0583	DNA-binding transcription factor activity
RD05_RS09645	COG2346	COG2346, Truncated hemoglobins
RD05_RS09775	COG2207	Transcriptional regulator
RD05_RS09820	COG1132	(ABC) transporter
RD05_RS09845	COG0659	secondary active sulfate transmembrane transporter activity
RD05_RS09875	COG2169	Transcriptional regulator
RD05_RS09880	COG5507	3-demethylubiquinone-9 3-methyltransferase
RD05_RS09885	COG0384	phenazine biosynthesis protein PhzF
RD05_RS09890	COG0583	DNA-binding transcription factor activity
RD05_RS09895	COG2733	membrane
RD05_RS09910	COG1012	belongs to the aldehyde dehydrogenase family
RD05_RS09915	COG3284	Transcriptional regulator
RD05_RS09930	COG1346	cytolysis
RD05_RS09935	COG1380	Effector of murein hydrolase LrgA
RD05_RS09940	COG4106	trans-aconitate 2-methyltransferase activity
RD05_RS09940	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
RD05_RS09950	COG0156	8-amino-7-oxononanoate synthase activity
RD05_RS10020	COG1131	(ABC) transporter
RD05_RS10025	COG0842	Transport permease protein
RD05_RS10030	COG0628	permease
RD05_RS10060	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
RD05_RS10070	COG0828	Belongs to the bacterial ribosomal protein bS21 family
RD05_RS10075	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
RD05_RS10080	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
RD05_RS10085	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
RD05_RS10090	COG0330	HflC and HflK could
RD05_RS10095	COG0330	HflC and HflK could
RD05_RS10100	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
RD05_RS10105	COG1923	regulation of RNA biosynthetic process
RD05_RS10110	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
RD05_RS10115	COG1160	GTP binding
RD05_RS10120	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
RD05_RS10125	COG2976	Protein conserved in bacteria
RD05_RS10130	COG0124	histidyl-tRNA synthetase
RD05_RS10135	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
RD05_RS10145	COG0820	rRNA (adenine-C2-)-methyltransferase activity
RD05_RS10150	COG0105	UTP biosynthetic process
RD05_RS10155	COG0525	valine-tRNA ligase activity
RD05_RS10170	COG0642	Histidine kinase
RD05_RS10190	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
RD05_RS10195	COG0336	Belongs to the RNA methyltransferase TrmD family
RD05_RS10200	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
RD05_RS10205	COG0228	four-way junction DNA binding
RD05_RS10215	COG0425	Belongs to the sulfur carrier protein TusA family
RD05_RS10220	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
RD05_RS10265	COG0154	amidase activity
RD05_RS10270	COG4172	Belongs to the ABC transporter superfamily
RD05_RS10275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RD05_RS10280	COG0601	transmembrane transport
RD05_RS10285	COG0747	negative chemotaxis
RD05_RS10310	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RD05_RS10320	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
RD05_RS10335	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
RD05_RS10340	COG3395	kinase activity
RD05_RS10360	COG1024	Enoyl-CoA hydratase
RD05_RS10380	COG0633	Ferredoxin
RD05_RS10385	COG0443	Heat shock 70 kDa protein
RD05_RS10390	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
RD05_RS10395	COG0316	Belongs to the HesB IscA family
RD05_RS10400	COG0822	iron-sulfur transferase activity
RD05_RS10405	COG1104	cysteine desulfurase activity
RD05_RS10415	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
RD05_RS10420	COG0556	nucleotide-excision repair
RD05_RS10430	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
RD05_RS10435	COG3468	outer membrane autotransporter barrel domain protein
RD05_RS10460	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
RD05_RS10475	COG1960	acyl-CoA dehydrogenase activity
RD05_RS10480	COG1028	Short-chain dehydrogenase reductase Sdr
RD05_RS10485	COG0183	Belongs to the thiolase family
RD05_RS10495	COG1024	Enoyl-CoA hydratase
RD05_RS10510	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD05_RS10515	COG0583	DNA-binding transcription factor activity
RD05_RS10520	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
RD05_RS10525	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
RD05_RS10530	COG0740	serine-type endopeptidase activity
RD05_RS10535	COG0544	peptidyl-prolyl cis-trans isomerase activity
RD05_RS10545	COG1278	Cold shock
RD05_RS10555	COG1278	Cold shock
RD05_RS10590	COG2171	N-acyltransferase activity
RD05_RS10595	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RD05_RS10600	COG2890	protein-(glutamine-N5) methyltransferase activity
RD05_RS10605	COG0488	(ABC) transporter
RD05_RS10610	COG4771	TonB-dependent receptor
RD05_RS10615	COG0210	DNA helicase
RD05_RS10635	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
RD05_RS10635	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
RD05_RS10640	COG0196	riboflavin kinase activity
RD05_RS10645	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
RD05_RS10650	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
RD05_RS10655	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
RD05_RS10665	COG1522	sequence-specific DNA binding
RD05_RS10680	COG2951	lytic endotransglycosylase activity
RD05_RS10685	COG2833	Protein of unknown function (DUF455)
RD05_RS10705	COG0189	ligase activity
RD05_RS10705	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
RD05_RS10710	COG1181	Belongs to the D-alanine--D-alanine ligase family
RD05_RS10710	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
RD05_RS10715	COG3237	CsbD-like
RD05_RS10725	COG2823	Periplasmic or secreted lipoprotein
RD05_RS10740	COG4181	ATPase activity
RD05_RS10750	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
RD05_RS10755	COG0584	glycerophosphoryl diester phosphodiesterase
RD05_RS10760	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
RD05_RS10770	COG0678	peroxiredoxin activity
RD05_RS10770	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
RD05_RS10780	COG0789	Transcriptional regulator
RD05_RS10785	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
RD05_RS10815	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
RD05_RS10820	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
RD05_RS10830	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
RD05_RS10835	COG2252	PERMEase
RD05_RS10845	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RD05_RS10875	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
RD05_RS10880	COG2358	TRAP transporter, solute receptor (TAXI family
RD05_RS10910	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RD05_RS10915	COG1366	Belongs to the anti-sigma-factor antagonist family
RD05_RS10920	COG2172	sigma factor antagonist activity
RD05_RS10925	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
RD05_RS10935	COG2770	Histidine kinase
RD05_RS10935	COG2208	phosphoserine phosphatase activity
RD05_RS10960	COG1595	DNA-templated transcription, initiation
RD05_RS10975	COG4792	protein secretion
RD05_RS10980	COG4791	protein targeting
RD05_RS10985	COG4794	Type iii secretion
RD05_RS10990	COG4790	Type iii secretion
RD05_RS11025	COG4669	(LipO)protein
RD05_RS11090	COG4789	Type iii secretion
RD05_RS11120	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
RD05_RS11125	COG0840	transmembrane signaling receptor activity
RD05_RS11130	COG2233	PERMEase
RD05_RS11155	COG0492	ferredoxin-NADP+ reductase activity
RD05_RS11160	COG1840	ABC-type Fe3 transport system, periplasmic component
RD05_RS11165	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RD05_RS11170	COG1178	ABC-type Fe3 transport system permease component
RD05_RS11175	COG3842	ATPase activity
RD05_RS11180	COG0583	DNA-binding transcription factor activity
RD05_RS11200	COG0501	Belongs to the peptidase M48B family
RD05_RS11210	COG0697	spore germination
RD05_RS11220	COG1846	Transcriptional regulator
RD05_RS11230	COG1566	PFAM secretion protein HlyD family protein
RD05_RS11235	COG2814	Major facilitator Superfamily
RD05_RS11240	COG0473	3-isopropylmalate dehydrogenase activity
RD05_RS11250	COG0747	negative chemotaxis
RD05_RS11260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RD05_RS11275	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
RD05_RS11300	COG1012	belongs to the aldehyde dehydrogenase family
RD05_RS11310	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
RD05_RS11315	COG1115	amino acid carrier protein
RD05_RS11320	COG0433	COG0433 Predicted ATPase
RD05_RS11325	COG0217	transcriptional regulatory protein
RD05_RS11330	COG0151	Belongs to the GarS family
RD05_RS11335	COG0408	coproporphyrinogen oxidase activity
RD05_RS11340	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
RD05_RS11345	COG0799	negative regulation of ribosome biogenesis
RD05_RS11350	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
RD05_RS11355	COG0424	maF-like protein
RD05_RS11360	COG3468	outer membrane autotransporter barrel domain protein
RD05_RS11400	COG1530	ribonuclease E activity
RD05_RS11405	COG0077	Prephenate dehydratase
RD05_RS11420	COG1132	(ABC) transporter
RD05_RS11425	COG0859	PFAM glycosyl transferase family 9
RD05_RS11450	COG2194	sulfuric ester hydrolase activity
RD05_RS11455	COG0438	transferase activity, transferring glycosyl groups
RD05_RS11460	COG0463	Glycosyl transferase, family 2
RD05_RS11465	COG0726	polysaccharide deacetylase
RD05_RS11470	COG0438	transferase activity, transferring glycosyl groups
RD05_RS11485	COG1643	Atp-dependent helicase
RD05_RS11490	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
RD05_RS11490	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
RD05_RS11495	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
RD05_RS11505	COG0704	Plays a role in the regulation of phosphate uptake
RD05_RS11510	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
RD05_RS11515	COG1960	acyl-CoA dehydrogenase activity
RD05_RS11540	COG1177	transmembrane transport
RD05_RS11545	COG1176	ABC-type spermidine putrescine transport system, permease component I
RD05_RS11550	COG3842	ATPase activity
RD05_RS11555	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
RD05_RS11570	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
RD05_RS11575	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
RD05_RS11585	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
RD05_RS11585	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
RD05_RS11605	COG0372	Belongs to the citrate synthase family
RD05_RS11610	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
RD05_RS11615	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
RD05_RS11620	COG1053	succinate dehydrogenase
RD05_RS11625	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
RD05_RS11630	COG2009	succinate dehydrogenase
RD05_RS11635	COG2188	Transcriptional regulator
RD05_RS11640	COG0039	L-malate dehydrogenase activity
RD05_RS11670	COG1981	membrane
RD05_RS11695	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RD05_RS11705	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
RD05_RS11735	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
RD05_RS11740	COG0148	phosphopyruvate hydratase activity
RD05_RS11750	COG2877	3-deoxy-8-phosphooctulonate synthase activity
RD05_RS11755	COG0504	CTP synthase activity
RD05_RS11780	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RD05_RS11790	COG0747	negative chemotaxis
RD05_RS11795	COG4172	Belongs to the ABC transporter superfamily
RD05_RS11800	COG1446	asparaginase
RD05_RS11830	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
RD05_RS11845	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
RD05_RS11850	COG0697	spore germination
RD05_RS11855	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RD05_RS11865	COG3193	protein, possibly involved in utilization of glycolate and propanediol
RD05_RS11870	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RD05_RS11875	COG0791	NLP P60 protein
RD05_RS11890	COG0583	DNA-binding transcription factor activity
RD05_RS11905	COG0583	DNA-binding transcription factor activity
RD05_RS11915	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
RD05_RS11930	COG0670	Belongs to the BI1 family
RD05_RS11935	COG3181	Tripartite tricarboxylate transporter family receptor
RD05_RS11950	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
RD05_RS11960	COG1381	Involved in DNA repair and RecF pathway recombination
RD05_RS11965	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
RD05_RS11970	COG0571	ribonuclease III activity
RD05_RS11975	COG0681	Belongs to the peptidase S26 family
RD05_RS11980	COG0481	GTPase activity
RD05_RS11985	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RD05_RS12010	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
RD05_RS12015	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RD05_RS12030	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
RD05_RS12035	COG0416	fatty acid biosynthetic process
RD05_RS12040	COG0333	Belongs to the bacterial ribosomal protein bL32 family
RD05_RS12045	COG1399	metal-binding, possibly nucleic acid-binding protein
RD05_RS12050	COG0424	maF-like protein
RD05_RS12060	COG3023	N-Acetylmuramoyl-L-alanine amidase
RD05_RS12065	COG1289	transmembrane transporter activity
RD05_RS12075	COG3022	response to hydroperoxide
RD05_RS12090	COG0135	phosphoribosylanthranilate isomerase activity
RD05_RS12105	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
RD05_RS12110	COG0101	tRNA pseudouridine synthase activity
RD05_RS12120	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
RD05_RS12125	COG0473	3-isopropylmalate dehydrogenase activity
RD05_RS12130	COG0066	3-isopropylmalate dehydratase activity
RD05_RS12135	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
RD05_RS12145	COG1122	ATPase activity
RD05_RS12175	COG0437	4 iron, 4 sulfur cluster binding
RD05_RS12180	COG3383	formate dehydrogenase (NAD+) activity
RD05_RS12180	COG0243	molybdopterin cofactor binding
RD05_RS12210	COG0489	protein tyrosine kinase activity
RD05_RS12215	COG0746	molybdenum cofactor guanylyltransferase activity
RD05_RS12220	COG0303	'Molybdopterin
RD05_RS12225	COG1763	Mo-molybdopterin cofactor biosynthetic process
RD05_RS12235	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
RD05_RS12240	COG5001	Diguanylate cyclase
RD05_RS12260	COG3842	ATPase activity
RD05_RS12270	COG0406	alpha-ribazole phosphatase activity
RD05_RS12280	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
RD05_RS12285	COG0505	Belongs to the CarA family
RD05_RS12290	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
RD05_RS12320	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
RD05_RS12325	COG1960	acyl-CoA dehydrogenase activity
RD05_RS12335	COG2867	negative regulation of translational initiation
RD05_RS12345	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
RD05_RS12350	COG3706	GGDEF domain
RD05_RS12355	COG0330	HflC and HflK could
RD05_RS12370	COG0518	GMP synthase (glutamine-hydrolyzing) activity
RD05_RS12370	COG0519	Catalyzes the synthesis of GMP from XMP
RD05_RS12380	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
RD05_RS12385	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RD05_RS12390	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
RD05_RS12395	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
RD05_RS12405	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
RD05_RS12410	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
RD05_RS12415	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
RD05_RS12420	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
RD05_RS12425	COG0750	zinc metalloprotease
RD05_RS12430	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
RD05_RS12440	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
RD05_RS12445	COG0233	cytoplasmic translational termination
RD05_RS12450	COG0528	UMP kinase activity
RD05_RS12455	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
RD05_RS12460	COG0052	Belongs to the universal ribosomal protein uS2 family
RD05_RS12465	COG0024	Methionine aminopeptidase
RD05_RS12470	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
RD05_RS12500	COG0285	dihydrofolate synthase activity
RD05_RS12535	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
RD05_RS12545	COG1677	Flagellar hook-basal body complex protein FliE
RD05_RS12555	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
RD05_RS12565	COG1157	protein secretion by the type III secretion system
RD05_RS12590	COG1580	Controls the rotational direction of flagella during chemotaxis
RD05_RS12610	COG1338	Plays a role in the flagellum-specific transport system
RD05_RS12630	COG0840	transmembrane signaling receptor activity
RD05_RS12635	COG0840	transmembrane signaling receptor activity
RD05_RS12640	COG0840	transmembrane signaling receptor activity
RD05_RS12650	COG1256	bacterial-type flagellum assembly
RD05_RS12660	COG1706	bacterial-type flagellum-dependent cell motility
RD05_RS12665	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
RD05_RS12680	COG1749	Flagellar hook protein flgE
RD05_RS12690	COG1558	bacterial-type flagellum-dependent cell motility
RD05_RS12695	COG1815	bacterial-type flagellum-dependent cell motility
RD05_RS12735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RD05_RS12740	COG0765	amino acid transport
RD05_RS12745	COG1126	abc transporter atp-binding protein
RD05_RS12760	COG4948	Mandelate Racemase Muconate Lactonizing
RD05_RS12765	COG3181	Tripartite tricarboxylate transporter family receptor
RD05_RS12775	COG0066	3-isopropylmalate dehydratase activity
RD05_RS12790	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD05_RS12800	COG3181	Tripartite tricarboxylate transporter family receptor
RD05_RS12810	COG1802	Transcriptional regulator
RD05_RS12825	COG0583	DNA-binding transcription factor activity
RD05_RS12845	COG1695	Transcriptional regulator
RD05_RS12850	COG3568	Endonuclease Exonuclease Phosphatase
RD05_RS12855	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RD05_RS12870	COG0392	lysyltransferase activity
RD05_RS12910	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
RD05_RS12920	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
RD05_RS12930	COG1640	4-alpha-glucanotransferase
RD05_RS12945	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
RD05_RS12975	COG0667	Aldo Keto reductase
RD05_RS12990	COG2259	Doxx family
RD05_RS13020	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD05_RS13040	COG0386	Belongs to the glutathione peroxidase family
RD05_RS13045	COG0625	glutathione transferase activity
RD05_RS13060	COG0095	Lipoate-protein ligase
RD05_RS13075	COG0688	phosphatidylethanolamine metabolic process
RD05_RS13085	COG1464	Belongs to the NlpA lipoprotein family
RD05_RS13100	COG2363	Small membrane protein
RD05_RS13125	COG3842	ATPase activity
RD05_RS13130	COG0395	ABC-type sugar transport system, permease component
RD05_RS13135	COG1175	transmembrane transport
RD05_RS13140	COG1653	transport
RD05_RS13150	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
RD05_RS13165	COG0559	Belongs to the binding-protein-dependent transport system permease family
RD05_RS13185	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
RD05_RS13200	COG0697	spore germination
RD05_RS13210	COG2311	Membrane
RD05_RS13235	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
RD05_RS13245	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
RD05_RS13250	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
RD05_RS13255	COG1760	l-serine dehydratase
RD05_RS13260	COG1283	sodium-dependent phosphate transmembrane transporter activity
RD05_RS13265	COG0412	Dienelactone hydrolase
RD05_RS13280	COG1611	Belongs to the LOG family
RD05_RS13300	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
RD05_RS13305	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
RD05_RS13310	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
RD05_RS13315	COG2251	uridine kinase activity
RD05_RS13315	COG0195	Participates in both transcription termination and antitermination
RD05_RS13320	COG0779	Required for maturation of 30S ribosomal subunits
RD05_RS13325	COG1187	pseudouridine synthase activity
RD05_RS13330	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
RD05_RS13340	COG0583	DNA-binding transcription factor activity
RD05_RS13350	COG0523	cobalamin synthesis protein
RD05_RS13370	COG0625	glutathione transferase activity
RD05_RS13375	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
RD05_RS13380	COG1047	Peptidyl-prolyl cis-trans
RD05_RS13385	COG2003	Belongs to the UPF0758 family
RD05_RS13390	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
RD05_RS13395	COG3483	tryptophan 2,3-dioxygenase activity
RD05_RS13400	COG0254	rRNA binding
RD05_RS13410	COG0534	Mate efflux family protein
RD05_RS13430	COG2304	oxidoreductase activity
RD05_RS13450	COG1028	Short-chain dehydrogenase reductase Sdr
RD05_RS13455	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
RD05_RS13460	COG1562	ergosterol biosynthetic process
RD05_RS13465	COG1562	ergosterol biosynthetic process
RD05_RS13470	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
RD05_RS13470	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
RD05_RS13475	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
RD05_RS13485	COG0842	Transport permease protein
RD05_RS13490	COG1131	(ABC) transporter
RD05_RS13510	COG1477	protein flavinylation
RD05_RS13525	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
RD05_RS13540	COG5564	TIM-barrel signal transduction protein
RD05_RS13545	COG5441	Belongs to the UPF0261 family
RD05_RS13555	COG3468	outer membrane autotransporter barrel domain protein
RD05_RS13560	COG3468	outer membrane autotransporter barrel domain protein
RD05_RS13570	COG0542	response to heat
RD05_RS13575	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RD05_RS13590	COG0494	nUDIX hydrolase
RD05_RS13595	COG3530	Putative quorum-sensing-regulated virulence factor
RD05_RS13605	COG1595	DNA-templated transcription, initiation
RD05_RS13610	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RD05_RS13645	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RD05_RS13650	COG0765	amino acid transport
RD05_RS13655	COG0765	amino acid transport
RD05_RS13680	COG2988	succinylglutamate desuccinylase activity
RD05_RS13705	COG3181	Tripartite tricarboxylate transporter family receptor
RD05_RS13710	COG2084	Dehydrogenase
RD05_RS13725	COG1619	proteins homologs of microcin C7 resistance protein MccF
RD05_RS13740	COG2814	Major facilitator Superfamily
RD05_RS13750	COG0583	DNA-binding transcription factor activity
RD05_RS13790	COG0672	)-iron permease
RD05_RS13805	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
RD05_RS13810	COG1028	Short-chain dehydrogenase reductase Sdr
RD05_RS13815	COG3243	poly(R)-hydroxyalkanoic acid synthase
RD05_RS13825	COG0564	pseudouridine synthase activity
RD05_RS13835	COG1199	ATP-dependent helicase activity
RD05_RS13840	COG2183	response to ionizing radiation
RD05_RS13845	COG0180	Tryptophanyl-tRNA synthetase
RD05_RS13865	COG3181	Tripartite tricarboxylate transporter family receptor
RD05_RS13875	COG0583	DNA-binding transcription factor activity
RD05_RS13880	COG1028	Short-chain dehydrogenase reductase Sdr
RD05_RS13885	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
RD05_RS13890	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RD05_RS13895	COG0508	dehydrogenase complex catalyzes the overall conversion of
RD05_RS13900	COG0567	Dehydrogenase, E1 component
RD05_RS13905	COG1297	OPT oligopeptide transporter protein
RD05_RS13910	COG1297	OPT oligopeptide transporter protein
RD05_RS13915	COG1522	sequence-specific DNA binding
RD05_RS13925	COG0280	phosphate acetyltransferase
RD05_RS13925	COG0281	malic enzyme
RD05_RS13930	COG3539	Fimbrial protein
RD05_RS13945	COG0613	PHP domain protein
RD05_RS13980	COG0084	hydrolase, TatD family'
RD05_RS13985	COG1136	(ABC) transporter
RD05_RS14000	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
RD05_RS14005	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
RD05_RS14010	COG1028	Short-chain dehydrogenase reductase Sdr
RD05_RS14015	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
RD05_RS14030	COG1022	Amp-dependent synthetase and ligase
RD05_RS14065	COG2205	protein histidine kinase activity
RD05_RS14070	COG0745	RESPONSE REGULATOR receiver
RD05_RS14075	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
RD05_RS14085	COG1295	ribonuclease BN
RD05_RS14100	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
RD05_RS14125	COG1534	Rna-binding protein
RD05_RS14130	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
RD05_RS14135	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
RD05_RS14145	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
RD05_RS14155	COG0248	Ppx GppA phosphatase
RD05_RS14180	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
RD05_RS14195	COG2732	(Barnase) inhibitor
RD05_RS14205	COG0281	malic enzyme
RD05_RS14205	COG0280	phosphate acetyltransferase
RD05_RS14215	COG0436	Aminotransferase
RD05_RS14220	COG0741	lytic transglycosylase activity
RD05_RS14225	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
RD05_RS14250	COG1648	precorrin-2 dehydrogenase activity
RD05_RS14250	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
RD05_RS14255	COG3468	outer membrane autotransporter barrel domain protein
RD05_RS14265	COG3468	outer membrane autotransporter barrel domain protein
RD05_RS14275	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
RD05_RS14280	COG2027	D-alanyl-D-alanine carboxypeptidase
RD05_RS14285	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
RD05_RS14290	COG0343	queuine tRNA-ribosyltransferase activity
RD05_RS14295	COG1862	Preprotein translocase
RD05_RS14300	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RD05_RS14305	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RD05_RS14320	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
RD05_RS14325	COG1702	phosphate starvation-inducible protein PhoH
RD05_RS14330	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
RD05_RS14335	COG4535	Mg2 and Co2 transporter CorC
RD05_RS14345	COG0667	Aldo Keto reductase
RD05_RS14370	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
RD05_RS14375	COG0745	RESPONSE REGULATOR receiver
RD05_RS14380	COG2201	protein-glutamate methylesterase activity
RD05_RS14390	COG0840	transmembrane signaling receptor activity
RD05_RS14405	COG0745	RESPONSE REGULATOR receiver
RD05_RS14440	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
RD05_RS14450	COG0739	heme binding
RD05_RS14460	COG0521	Mo-molybdopterin cofactor biosynthetic process
RD05_RS14470	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
RD05_RS14500	COG0625	glutathione transferase activity
RD05_RS14515	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
RD05_RS14520	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
RD05_RS14525	COG0126	phosphoglycerate kinase activity
RD05_RS14530	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
RD05_RS14535	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
RD05_RS14540	COG1385	rRNA (uridine-N3-)-methyltransferase activity
RD05_RS14555	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
RD05_RS14560	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RD05_RS14565	COG0508	dehydrogenase complex catalyzes the overall conversion of
RD05_RS14570	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
RD05_RS14580	COG4566	intracellular signal transduction
RD05_RS14585	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
RD05_RS14590	COG0339	signal peptide processing
RD05_RS14595	COG1999	signal sequence binding
RD05_RS14615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RD05_RS14625	COG1187	pseudouridine synthase activity
RD05_RS14630	COG3161	chorismate lyase activity
RD05_RS14635	COG2814	Major facilitator Superfamily
RD05_RS14645	COG0667	Aldo Keto reductase
RD05_RS14660	COG0335	large ribosomal subunit rRNA binding
RD05_RS14690	COG0175	sulfate reduction
RD05_RS14695	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
RD05_RS14700	COG4208	sulfate ABC transporter
RD05_RS14705	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
RD05_RS14720	COG0450	alkyl hydroperoxide reductase
RD05_RS14725	COG1960	acyl-CoA dehydrogenase activity
RD05_RS14740	COG0123	including yeast histone deacetylase and acetoin utilization protein
RD05_RS14745	COG2951	lytic endotransglycosylase activity
RD05_RS14760	COG1555	photosystem II stabilization
RD05_RS14760	COG1596	polysaccharide export
RD05_RS14765	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RD05_RS14770	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
RD05_RS14775	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
RD05_RS14795	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
RD05_RS14800	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
RD05_RS14805	COG0287	Prephenate dehydrogenase
RD05_RS14815	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
RD05_RS14830	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
RD05_RS14840	COG2814	Major facilitator Superfamily
RD05_RS14865	COG0583	DNA-binding transcription factor activity
RD05_RS14900	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
RD05_RS14915	COG0667	Aldo Keto reductase
RD05_RS14925	COG5265	(ABC) transporter
RD05_RS14970	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
RD05_RS14975	COG0439	Biotin carboxylase
RD05_RS14980	COG2188	Transcriptional regulator
RD05_RS15005	COG0511	ligase activity, forming carbon-carbon bonds
RD05_RS15015	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
RD05_RS15035	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
RD05_RS15050	COG0500	methyltransferase
RD05_RS15055	COG5265	(ABC) transporter
RD05_RS15070	COG0028	Belongs to the TPP enzyme family
RD05_RS15075	COG0440	acetolactate synthase activity
RD05_RS15080	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
RD05_RS15085	COG1183	phosphatidylcholine synthase activity
RD05_RS15095	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
RD05_RS15100	COG1185	polyribonucleotide nucleotidyltransferase activity
RD05_RS15115	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
RD05_RS15135	COG0149	triose-phosphate isomerase activity
RD05_RS15140	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
RD05_RS15150	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
RD05_RS15160	COG3799	methylaspartate ammonia-lyase activity
RD05_RS15200	COG0583	DNA-binding transcription factor activity
RD05_RS15205	COG0626	cystathionine gamma-synthase activity
RD05_RS15210	COG3608	succinylglutamate desuccinylase aspartoacylase
RD05_RS15230	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RD05_RS15250	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
RD05_RS15265	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RD05_RS15270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RD05_RS15275	COG1733	regulation of RNA biosynthetic process
RD05_RS15285	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
RD05_RS15290	COG0583	DNA-binding transcription factor activity
RD05_RS15295	COG1597	lipid kinase activity
RD05_RS15305	COG0671	phosphoesterase, PA-phosphatase related
RD05_RS15330	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
RD05_RS15335	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RD05_RS15340	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RD05_RS15345	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RD05_RS15350	COG0649	NAD binding
RD05_RS15355	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
RD05_RS15365	COG1034	ATP synthesis coupled electron transport
RD05_RS15370	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
RD05_RS15375	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RD05_RS15385	COG0713	ATP synthesis coupled electron transport
RD05_RS15400	COG1007	ATP synthesis coupled electron transport
RD05_RS15410	COG4774	siderophore transport
RD05_RS15415	COG4774	siderophore transport
RD05_RS15430	COG0028	Belongs to the TPP enzyme family
RD05_RS15435	COG3181	Tripartite tricarboxylate transporter family receptor
RD05_RS15440	COG0583	DNA-binding transcription factor activity
RD05_RS15445	COG0560	Phosphoserine phosphatase
RD05_RS15450	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
RD05_RS15455	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
RD05_RS15460	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
RD05_RS15470	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
RD05_RS15475	COG0308	aminopeptidase N
RD05_RS15495	COG0028	Belongs to the TPP enzyme family
RD05_RS15515	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RD05_RS15525	COG0318	PFAM AMP-dependent synthetase and ligase
RD05_RS15535	COG1802	Transcriptional regulator
RD05_RS15545	COG1802	Transcriptional regulator
RD05_RS15555	COG1028	Short-chain dehydrogenase reductase Sdr
RD05_RS15575	COG1126	abc transporter atp-binding protein
RD05_RS15580	COG0765	amino acid transport
RD05_RS15600	COG1538	Outer membrane efflux protein
RD05_RS15605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RD05_RS15610	COG2274	protein secretion by the type I secretion system
RD05_RS15615	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
RD05_RS15625	COG2994	toxin metabolic process
RD05_RS15640	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RD05_RS15645	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
RD05_RS15655	COG0583	DNA-binding transcription factor activity
RD05_RS15665	COG0142	geranyltranstransferase activity
RD05_RS15675	COG0261	This protein binds to 23S rRNA in the presence of protein L20
RD05_RS15680	COG0211	Belongs to the bacterial ribosomal protein bL27 family
RD05_RS15685	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
RD05_RS15690	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
RD05_RS15730	COG3712	iron ion homeostasis
RD05_RS15735	COG4774	siderophore transport
RD05_RS15740	COG2353	YceI-like domain
RD05_RS15760	COG0019	diaminopimelate decarboxylase activity
RD05_RS15780	COG0747	negative chemotaxis
RD05_RS15785	COG0601	transmembrane transport
RD05_RS15790	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RD05_RS15800	COG0154	amidase activity
RD05_RS15805	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
RD05_RS15830	COG2154	pterin-4-alpha-carbinolamine dehydratase
RD05_RS15840	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
RD05_RS15850	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
RD05_RS15855	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
RD05_RS15860	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
RD05_RS15865	COG1929	Belongs to the glycerate kinase type-1 family
RD05_RS15870	COG0469	pyruvate kinase activity
RD05_RS15875	COG0700	Nucleoside recognition
RD05_RS15905	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
RD05_RS15910	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RD05_RS15925	COG0823	Involved in the tonB-independent uptake of proteins
RD05_RS15935	COG0848	biopolymer transport protein
RD05_RS15940	COG0811	peptide transport
RD05_RS15945	COG0824	Thioesterase
RD05_RS15950	COG0442	prolyl-tRNA aminoacylation
RD05_RS15955	COG0494	nUDIX hydrolase
RD05_RS15970	COG2135	peptidase activity
RD05_RS16035	COG1196	nuclear chromosome segregation
RD05_RS16175	COG1464	Belongs to the NlpA lipoprotein family
RD05_RS16205	COG4211	Belongs to the binding-protein-dependent transport system permease family
RD05_RS16215	COG0154	amidase activity
RD05_RS16220	COG0288	reversible hydration of carbon dioxide
RD05_RS16235	COG0514	ATP-dependent DNA helicase (RecQ)
RD05_RS16240	COG2255	four-way junction helicase activity
RD05_RS16255	COG0632	four-way junction helicase activity
RD05_RS16260	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
RD05_RS16280	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RD05_RS16290	COG0006	proline dipeptidase activity
RD05_RS16315	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
RD05_RS16330	COG4783	chaperone-mediated protein folding
RD05_RS16335	COG0429	hydrolase of the alpha beta-hydrolase fold
RD05_RS16365	COG0513	Belongs to the DEAD box helicase family
RD05_RS16385	COG1058	Belongs to the CinA family
RD05_RS16385	COG1546	Belongs to the CinA family
RD05_RS16390	COG1414	Transcriptional regulator
RD05_RS16410	COG0167	dihydroorotate dehydrogenase activity
RD05_RS16415	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
RD05_RS16420	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
RD05_RS16430	COG0583	DNA-binding transcription factor activity
RD05_RS16490	COG0280	phosphate acetyltransferase
RD05_RS16490	COG0281	malic enzyme
RD05_RS16500	COG0601	transmembrane transport
RD05_RS16505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RD05_RS16510	COG4172	Belongs to the ABC transporter superfamily
RD05_RS16540	COG0640	Transcriptional regulator
RD05_RS16555	COG3135	benzoate transporter
RD05_RS16560	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
RD05_RS16565	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
RD05_RS16570	COG0742	ribosomal rna small subunit methyltransferase
RD05_RS16590	COG3639	organic phosphonate transmembrane transporter activity
RD05_RS16595	COG3639	organic phosphonate transmembrane transporter activity
RD05_RS16600	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
RD05_RS16635	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
RD05_RS16640	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
RD05_RS16650	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
RD05_RS16655	COG1058	Belongs to the CinA family
RD05_RS16655	COG1546	Belongs to the CinA family
RD05_RS16660	COG0284	orotidine-5'-phosphate decarboxylase activity
RD05_RS16665	COG1252	NADH dehydrogenase
RD05_RS16680	COG3468	outer membrane autotransporter barrel domain protein
RD05_RS16685	COG0459	protein refolding
RD05_RS16690	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
RD05_RS16710	COG1053	succinate dehydrogenase
RD05_RS16720	COG0583	DNA-binding transcription factor activity
RD05_RS16725	COG1053	succinate dehydrogenase
RD05_RS16745	COG3706	GGDEF domain
RD05_RS16780	COG1262	PFAM Formylglycine-generating sulfatase enzyme
RD05_RS16785	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
RD05_RS16795	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RD05_RS16805	COG0069	glutamate synthase activity
RD05_RS16810	COG2391	methyltransferase activity
RD05_RS16815	COG0679	Auxin Efflux Carrier
RD05_RS16840	COG0557	exoribonuclease II activity
RD05_RS16845	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RD05_RS16855	COG3128	pkhd-type hydroxylase
RD05_RS16860	COG0776	regulation of translation
RD05_RS16890	COG0642	Histidine kinase
RD05_RS16895	COG3158	transport of potassium into the cell
RD05_RS16900	COG0137	argininosuccinate synthase activity
RD05_RS16905	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
RD05_RS16910	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
RD05_RS16920	COG0583	DNA-binding transcription factor activity
RD05_RS16930	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
RD05_RS16950	COG2186	Transcriptional regulator
RD05_RS16960	COG2223	nitrite transmembrane transporter activity
RD05_RS16970	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RD05_RS16975	COG0450	alkyl hydroperoxide reductase
RD05_RS16995	COG1214	PFAM Peptidase M22, glycoprotease
RD05_RS17000	COG1573	uracil-dna glycosylase
RD05_RS17005	COG0477	Major facilitator Superfamily
RD05_RS17010	COG1196	nuclear chromosome segregation
RD05_RS17020	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
RD05_RS17025	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
RD05_RS17040	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
RD05_RS17045	COG1122	ATPase activity
RD05_RS17050	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
RD05_RS17055	COG1268	BioY protein
RD05_RS17075	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
RD05_RS17110	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
RD05_RS17115	COG2878	Part of a membrane complex involved in electron transport
RD05_RS17130	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
RD05_RS17135	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
RD05_RS17140	COG0251	oxidation-reduction process
RD05_RS17150	COG3228	Belongs to the MtfA family
RD05_RS17155	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
RD05_RS17165	COG0133	tryptophan synthase activity
RD05_RS17170	COG0159	tryptophan synthase activity
RD05_RS17175	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
RD05_RS17180	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
RD05_RS17195	COG1530	ribonuclease E activity
RD05_RS17205	COG0546	phosphoglycolate phosphatase activity
RD05_RS17210	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
RD05_RS17215	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
RD05_RS17225	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD05_RS17230	COG0583	DNA-binding transcription factor activity
RD05_RS17240	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD05_RS17265	COG0251	oxidation-reduction process
RD05_RS17270	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
RD05_RS17270	COG1017	nitric oxide dioxygenase activity
RD05_RS17275	COG2031	fatty acid transporter
RD05_RS17280	COG1012	belongs to the aldehyde dehydrogenase family
RD05_RS17285	COG1802	Transcriptional regulator
RD05_RS17295	COG1278	Cold shock
RD05_RS17300	COG0583	DNA-binding transcription factor activity
RD05_RS17320	COG0183	Belongs to the thiolase family
RD05_RS17330	COG1960	acyl-CoA dehydrogenase activity
RD05_RS17335	COG0583	DNA-binding transcription factor activity
RD05_RS17340	COG3181	Tripartite tricarboxylate transporter family receptor
RD05_RS17345	COG1024	Enoyl-CoA hydratase
RD05_RS17350	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD05_RS17355	COG1253	flavin adenine dinucleotide binding
RD05_RS17360	COG1285	pathogenesis
RD05_RS17370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RD05_RS17385	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
RD05_RS17395	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RD05_RS17400	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
RD05_RS17415	COG2031	fatty acid transporter
RD05_RS17425	COG0786	glutamate:sodium symporter activity
RD05_RS17440	COG0463	Glycosyl transferase, family 2
RD05_RS17445	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
RD05_RS17470	COG0697	spore germination
RD05_RS17480	COG3181	Tripartite tricarboxylate transporter family receptor
RD05_RS17505	COG0028	Belongs to the TPP enzyme family
RD05_RS17510	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD05_RS17515	COG1024	Enoyl-CoA hydratase
RD05_RS17515	COG1250	3-hydroxyacyl-CoA dehydrogenase
RD05_RS17520	COG3181	Tripartite tricarboxylate transporter family receptor
RD05_RS17530	COG0492	ferredoxin-NADP+ reductase activity
RD05_RS17555	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD05_RS17565	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD05_RS17585	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
RD05_RS17600	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
RD05_RS17605	COG2823	Periplasmic or secreted lipoprotein
RD05_RS17620	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
RD05_RS17630	COG1309	transcriptional regulator
RD05_RS17635	COG0471	metal ion transport
RD05_RS17640	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
RD05_RS17645	COG0772	Belongs to the SEDS family
RD05_RS17650	COG0768	penicillin binding
RD05_RS17660	COG1792	Involved in formation and maintenance of cell shape
RD05_RS17665	COG1077	Cell shape determining protein MreB Mrl
RD05_RS17670	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
RD05_RS17675	COG0154	amidase activity
RD05_RS17680	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
RD05_RS17685	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
RD05_RS17690	COG0708	Exodeoxyribonuclease III
RD05_RS17695	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
RD05_RS17700	COG2860	membrane
RD05_RS17735	COG1012	belongs to the aldehyde dehydrogenase family
RD05_RS17745	COG3069	C4-dicarboxylate transmembrane transporter activity
RD05_RS17755	COG1802	Transcriptional regulator
RD05_RS17790	COG1595	DNA-templated transcription, initiation
RD05_RS17795	COG3712	iron ion homeostasis
RD05_RS17805	COG3720	iron ion transport
RD05_RS17810	COG4558	Periplasmic binding protein
RD05_RS17815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RD05_RS17820	COG1120	ATPase activity
RD05_RS17825	COG1683	Conserved Protein
RD05_RS17875	COG1234	tRNA 3'-trailer cleavage
RD05_RS17910	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
RD05_RS17920	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
RD05_RS17935	COG0540	Belongs to the ATCase OTCase family
RD05_RS17940	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
RD05_RS17945	COG1678	Uncharacterized ACR, COG1678
RD05_RS17955	COG0351	phosphomethylpyrimidine kinase
RD05_RS17960	COG0352	thiamine-phosphate diphosphorylase activity
RD05_RS17965	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
RD05_RS17990	COG1960	acyl-CoA dehydrogenase activity
RD05_RS17995	COG1024	Enoyl-CoA hydratase
RD05_RS18065	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
RD05_RS18075	COG0583	DNA-binding transcription factor activity
RD05_RS18080	COG2814	Major facilitator Superfamily
RD05_RS18085	COG0129	dihydroxy-acid dehydratase activity
RD05_RS18090	COG2207	Transcriptional regulator
RD05_RS18095	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RD05_RS18105	COG0657	acetylesterase activity
RD05_RS18110	COG0747	negative chemotaxis
RD05_RS18115	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RD05_RS18120	COG2808	Putative FMN-binding domain
RD05_RS18135	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
RD05_RS18140	COG1970	mechanosensitive ion channel activity
RD05_RS18145	COG0723	plastoquinol--plastocyanin reductase activity
RD05_RS18150	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
RD05_RS18155	COG2857	Cytochrome c1
RD05_RS18160	COG0625	glutathione transferase activity
RD05_RS18165	COG2969	positive regulation of protein catabolic process
RD05_RS18190	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
RD05_RS18205	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
RD05_RS18210	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
RD05_RS18215	COG4988	ABC transporter
RD05_RS18225	COG1294	oxidase, subunit
RD05_RS18250	COG1960	acyl-CoA dehydrogenase activity
RD05_RS18260	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD05_RS18265	COG0405	Gamma-glutamyltransferase
RD05_RS18275	COG3181	Tripartite tricarboxylate transporter family receptor
RD05_RS18285	COG0114	fumarate hydratase activity
RD05_RS18290	COG0802	atpase or kinase
RD05_RS18295	COG0860	N-Acetylmuramoyl-L-alanine amidase
RD05_RS18300	COG0586	Pfam SNARE associated Golgi protein
RD05_RS18305	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
RD05_RS18310	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
RD05_RS18315	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
RD05_RS18330	COG0617	tRNA 3'-terminal CCA addition
RD05_RS18355	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
RD05_RS18360	COG2188	Transcriptional regulator
RD05_RS18370	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RD05_RS18380	COG1028	Short-chain dehydrogenase reductase Sdr
RD05_RS18405	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RD05_RS18410	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
RD05_RS18415	COG1012	belongs to the aldehyde dehydrogenase family
RD05_RS18435	COG4257	antibiotic catabolic process
RD05_RS18445	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
RD05_RS18450	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
RD05_RS18460	COG1250	3-hydroxyacyl-CoA dehydrogenase
RD05_RS18465	COG2031	fatty acid transporter
RD05_RS18470	COG1028	Short-chain dehydrogenase reductase Sdr
RD05_RS18475	COG1414	Transcriptional regulator
RD05_RS18485	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
RD05_RS18500	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
RD05_RS18540	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
RD05_RS18540	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
RD05_RS18545	COG0509	glycine decarboxylation via glycine cleavage system
RD05_RS18550	COG0404	The glycine cleavage system catalyzes the degradation of glycine
RD05_RS18560	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
RD05_RS18570	COG2081	HI0933 family
RD05_RS18600	COG0717	Belongs to the dCTP deaminase family
RD05_RS18615	COG0489	protein tyrosine kinase activity
RD05_RS18625	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RD05_RS18625	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RD05_RS18630	COG1054	Belongs to the UPF0176 family
RD05_RS18665	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
RD05_RS18670	COG1280	lysine exporter protein (LysE YggA)
RD05_RS18675	COG0513	Belongs to the DEAD box helicase family
RD05_RS18685	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
RD05_RS18705	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
RD05_RS18720	COG2226	methyltransferase
RD05_RS18725	COG0745	RESPONSE REGULATOR receiver
RD05_RS18730	COG5002	protein histidine kinase activity
RD05_RS18740	COG5002	protein histidine kinase activity
RD05_RS18750	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RD05_RS18755	COG0583	DNA-binding transcription factor activity
RD05_RS18765	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
RD05_RS18770	COG1984	allophanate hydrolase subunit 2
RD05_RS18785	COG3181	Tripartite tricarboxylate transporter family receptor
RD05_RS18800	COG1024	Enoyl-CoA hydratase
RD05_RS18815	COG1802	Transcriptional regulator
RD05_RS18830	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
RD05_RS18835	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
RD05_RS18850	COG0583	DNA-binding transcription factor activity
RD05_RS18860	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
RD05_RS18870	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RD05_RS18875	COG0154	amidase activity
RD05_RS18885	COG1609	Transcriptional regulator
RD05_RS18905	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
RD05_RS18925	COG2814	Major facilitator Superfamily
RD05_RS18930	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
RD05_RS18950	COG1999	signal sequence binding
RD05_RS18955	COG0109	protoheme IX farnesyltransferase activity
RD05_RS18995	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
RD05_RS19015	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
RD05_RS19020	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
RD05_RS19030	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
RD05_RS19035	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
RD05_RS19045	COG0069	glutamate synthase activity
RD05_RS19045	COG0067	glutamate synthase
RD05_RS19045	COG0070	glutamate synthase
RD05_RS19055	COG3047	cAMP biosynthetic process
RD05_RS19065	COG1127	ABC transporter
RD05_RS19070	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
RD05_RS19075	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
RD05_RS19080	COG2853	Lipoprotein
RD05_RS19090	COG1131	(ABC) transporter
RD05_RS19095	COG0842	Transport permease protein
RD05_RS19105	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
RD05_RS19110	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
RD05_RS19115	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
RD05_RS19120	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
RD05_RS19125	COG0131	Imidazoleglycerol-phosphate dehydratase
RD05_RS19135	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
RD05_RS19140	COG0107	imidazoleglycerol-phosphate synthase activity
RD05_RS19145	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
RD05_RS19150	COG0140	phosphoribosyl-ATP diphosphatase activity
RD05_RS19155	COG0537	adenosine 5'-monophosphoramidase activity
RD05_RS19160	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
RD05_RS19165	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
RD05_RS19180	COG3181	Tripartite tricarboxylate transporter family receptor
RD05_RS19215	COG3702	type iv secretory pathway
RD05_RS19220	COG3451	type IV secretory pathway VirB4
RD05_RS19235	COG3736	Type IV secretory pathway, component VirB8
RD05_RS19240	COG3504	Conjugal transfer protein
RD05_RS19245	COG2948	multi-organism process
RD05_RS19250	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
RD05_RS19260	COG0697	spore germination
RD05_RS19280	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
RD05_RS19285	COG0747	negative chemotaxis
RD05_RS19290	COG0601	transmembrane transport
RD05_RS19295	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RD05_RS19300	COG0444	Belongs to the ABC transporter superfamily
RD05_RS19310	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
RD05_RS19320	COG0494	nUDIX hydrolase
RD05_RS19360	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
RD05_RS19365	COG0237	dephospho-CoA kinase activity
RD05_RS19370	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
RD05_RS19385	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
RD05_RS19390	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
RD05_RS19400	COG0477	Major facilitator Superfamily
RD05_RS19405	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
RD05_RS19420	COG1126	abc transporter atp-binding protein
RD05_RS19425	COG0765	amino acid transport
RD05_RS19430	COG4597	amino acid ABC transporter
RD05_RS19435	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RD05_RS19440	COG2884	Cell division ATP-binding protein ftsE
RD05_RS19445	COG2177	Part of the ABC transporter FtsEX involved in
RD05_RS19450	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
RD05_RS19460	COG1194	a g-specific adenine glycosylase
RD05_RS19470	COG2226	methyltransferase
RD05_RS19480	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD05_RS19485	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD05_RS19500	COG1024	Enoyl-CoA hydratase
RD05_RS19520	COG1024	Enoyl-CoA hydratase
RD05_RS19525	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD05_RS19530	COG3181	Tripartite tricarboxylate transporter family receptor
RD05_RS19540	COG0753	catalase activity
RD05_RS19545	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RD05_RS19550	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
RD05_RS19560	COG2175	clavaminate synthase activity
RD05_RS19565	COG1473	amidohydrolase
RD05_RS19570	COG4608	Belongs to the ABC transporter superfamily
RD05_RS19575	COG0444	Belongs to the ABC transporter superfamily
RD05_RS19590	COG0747	negative chemotaxis
RD05_RS19595	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
RD05_RS19630	COG0436	Aminotransferase
RD05_RS19635	COG1278	Cold shock