locus-tag	class	description
RD06_RS00005	COG0445	tRNA wobble uridine modification
RD06_RS00010	COG0357	Ribosomal RNA small subunit methyltransferase G
RD06_RS00015	COG1192	Involved in chromosome partitioning
RD06_RS00025	COG1475	DNA binding
RD06_RS00030	COG0252	asparaginase activity
RD06_RS00055	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
RD06_RS00065	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
RD06_RS00075	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
RD06_RS00080	COG0081	regulation of translation
RD06_RS00085	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
RD06_RS00090	COG0222	ribosome binding
RD06_RS00095	COG0085	RNA polymerase activity
RD06_RS00100	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
RD06_RS00140	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD06_RS00165	COG1024	Enoyl-CoA hydratase
RD06_RS00185	COG0752	glycyl-tRNA synthetase alpha subunit
RD06_RS00190	COG0751	glycine-tRNA ligase activity
RD06_RS00195	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
RD06_RS00200	COG0204	Acyl-transferase
RD06_RS00215	COG0242	peptide deformylase activity
RD06_RS00250	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
RD06_RS00260	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
RD06_RS00265	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
RD06_RS00265	COG2813	Specifically methylates the guanine in position
RD06_RS00275	COG2223	nitrite transmembrane transporter activity
RD06_RS00285	COG1794	racemase activity, acting on amino acids and derivatives
RD06_RS00290	COG1126	abc transporter atp-binding protein
RD06_RS00295	COG0765	amino acid transport
RD06_RS00300	COG0765	amino acid transport
RD06_RS00305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RD06_RS00365	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
RD06_RS00395	COG0326	Molecular chaperone. Has ATPase activity
RD06_RS00400	COG0625	glutathione transferase activity
RD06_RS00415	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
RD06_RS00420	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
RD06_RS00450	COG0438	transferase activity, transferring glycosyl groups
RD06_RS00455	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
RD06_RS00460	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
RD06_RS00490	COG0859	PFAM glycosyl transferase family 9
RD06_RS00505	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
RD06_RS00515	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
RD06_RS00520	COG1127	ABC transporter
RD06_RS00545	COG1686	Belongs to the peptidase S11 family
RD06_RS00555	COG2921	Belongs to the UPF0250 family
RD06_RS00560	COG0321	lipoyl(octanoyl) transferase activity
RD06_RS00565	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
RD06_RS00600	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
RD06_RS00610	COG0018	arginyl-trna synthetase
RD06_RS00630	COG0395	ABC-type sugar transport system, permease component
RD06_RS00635	COG1175	transmembrane transport
RD06_RS00640	COG1653	transport
RD06_RS00645	COG3842	ATPase activity
RD06_RS00650	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
RD06_RS00660	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
RD06_RS00680	COG1609	Transcriptional regulator
RD06_RS00690	COG0154	amidase activity
RD06_RS00695	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RD06_RS00705	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
RD06_RS00715	COG0583	DNA-binding transcription factor activity
RD06_RS00730	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
RD06_RS00735	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
RD06_RS00750	COG1802	Transcriptional regulator
RD06_RS00765	COG1024	Enoyl-CoA hydratase
RD06_RS00780	COG3181	Tripartite tricarboxylate transporter family receptor
RD06_RS00795	COG1984	allophanate hydrolase subunit 2
RD06_RS00800	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
RD06_RS00810	COG0583	DNA-binding transcription factor activity
RD06_RS00815	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RD06_RS00825	COG5002	protein histidine kinase activity
RD06_RS00840	COG0745	RESPONSE REGULATOR receiver
RD06_RS00845	COG2226	methyltransferase
RD06_RS00860	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
RD06_RS00880	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
RD06_RS00890	COG0513	Belongs to the DEAD box helicase family
RD06_RS00895	COG1280	lysine exporter protein (LysE YggA)
RD06_RS00900	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
RD06_RS00935	COG1054	Belongs to the UPF0176 family
RD06_RS00940	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RD06_RS00940	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RD06_RS00950	COG0489	protein tyrosine kinase activity
RD06_RS00965	COG0717	Belongs to the dCTP deaminase family
RD06_RS00995	COG2081	HI0933 family
RD06_RS01005	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
RD06_RS01015	COG0404	The glycine cleavage system catalyzes the degradation of glycine
RD06_RS01020	COG0509	glycine decarboxylation via glycine cleavage system
RD06_RS01025	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
RD06_RS01025	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
RD06_RS01065	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
RD06_RS01080	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
RD06_RS01090	COG1414	Transcriptional regulator
RD06_RS01095	COG1028	Short-chain dehydrogenase reductase Sdr
RD06_RS01100	COG2031	fatty acid transporter
RD06_RS01105	COG1250	3-hydroxyacyl-CoA dehydrogenase
RD06_RS01115	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
RD06_RS01120	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
RD06_RS01130	COG4257	antibiotic catabolic process
RD06_RS01150	COG1012	belongs to the aldehyde dehydrogenase family
RD06_RS01155	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
RD06_RS01160	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RD06_RS01185	COG1028	Short-chain dehydrogenase reductase Sdr
RD06_RS01195	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RD06_RS01205	COG2188	Transcriptional regulator
RD06_RS01210	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
RD06_RS01235	COG0617	tRNA 3'-terminal CCA addition
RD06_RS01250	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
RD06_RS01255	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
RD06_RS01260	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
RD06_RS01265	COG0586	Pfam SNARE associated Golgi protein
RD06_RS01270	COG0860	N-Acetylmuramoyl-L-alanine amidase
RD06_RS01275	COG0802	atpase or kinase
RD06_RS01280	COG0114	fumarate hydratase activity
RD06_RS01290	COG3181	Tripartite tricarboxylate transporter family receptor
RD06_RS01300	COG0405	Gamma-glutamyltransferase
RD06_RS01305	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD06_RS01315	COG1960	acyl-CoA dehydrogenase activity
RD06_RS01340	COG1294	oxidase, subunit
RD06_RS01350	COG4988	ABC transporter
RD06_RS01355	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
RD06_RS01360	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
RD06_RS01375	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
RD06_RS01400	COG2969	positive regulation of protein catabolic process
RD06_RS01405	COG0625	glutathione transferase activity
RD06_RS01410	COG2857	Cytochrome c1
RD06_RS01415	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
RD06_RS01420	COG0723	plastoquinol--plastocyanin reductase activity
RD06_RS01425	COG1970	mechanosensitive ion channel activity
RD06_RS01430	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
RD06_RS01445	COG2808	Putative FMN-binding domain
RD06_RS01450	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RD06_RS01455	COG0747	negative chemotaxis
RD06_RS01460	COG0657	acetylesterase activity
RD06_RS01470	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RD06_RS01475	COG2207	Transcriptional regulator
RD06_RS01480	COG0129	dihydroxy-acid dehydratase activity
RD06_RS01485	COG2814	Major facilitator Superfamily
RD06_RS01490	COG0583	DNA-binding transcription factor activity
RD06_RS01500	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
RD06_RS01570	COG1024	Enoyl-CoA hydratase
RD06_RS01575	COG1960	acyl-CoA dehydrogenase activity
RD06_RS01600	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
RD06_RS01605	COG0352	thiamine-phosphate diphosphorylase activity
RD06_RS01620	COG1678	Uncharacterized ACR, COG1678
RD06_RS01625	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
RD06_RS01630	COG0540	Belongs to the ATCase OTCase family
RD06_RS01645	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
RD06_RS01655	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
RD06_RS01690	COG1234	tRNA 3'-trailer cleavage
RD06_RS01735	COG1683	Conserved Protein
RD06_RS01740	COG1120	ATPase activity
RD06_RS01745	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RD06_RS01750	COG4558	Periplasmic binding protein
RD06_RS01755	COG3720	iron ion transport
RD06_RS01765	COG3712	iron ion homeostasis
RD06_RS01770	COG1595	DNA-templated transcription, initiation
RD06_RS01805	COG1802	Transcriptional regulator
RD06_RS01815	COG3069	C4-dicarboxylate transmembrane transporter activity
RD06_RS01825	COG1012	belongs to the aldehyde dehydrogenase family
RD06_RS01860	COG2860	membrane
RD06_RS01865	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
RD06_RS01870	COG0708	Exodeoxyribonuclease III
RD06_RS01875	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
RD06_RS01880	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
RD06_RS01885	COG0154	amidase activity
RD06_RS01890	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
RD06_RS01895	COG1077	Cell shape determining protein MreB Mrl
RD06_RS01900	COG1792	Involved in formation and maintenance of cell shape
RD06_RS01910	COG0768	penicillin binding
RD06_RS01915	COG0772	Belongs to the SEDS family
RD06_RS01920	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
RD06_RS01925	COG0471	metal ion transport
RD06_RS01930	COG1309	transcriptional regulator
RD06_RS01940	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
RD06_RS01955	COG2823	Periplasmic or secreted lipoprotein
RD06_RS01960	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
RD06_RS01975	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
RD06_RS01995	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD06_RS02005	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD06_RS02030	COG0492	ferredoxin-NADP+ reductase activity
RD06_RS02040	COG3181	Tripartite tricarboxylate transporter family receptor
RD06_RS02045	COG1250	3-hydroxyacyl-CoA dehydrogenase
RD06_RS02045	COG1024	Enoyl-CoA hydratase
RD06_RS02050	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD06_RS02055	COG0028	Belongs to the TPP enzyme family
RD06_RS02080	COG3181	Tripartite tricarboxylate transporter family receptor
RD06_RS02090	COG0697	spore germination
RD06_RS02115	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
RD06_RS02120	COG0463	Glycosyl transferase, family 2
RD06_RS02135	COG0786	glutamate:sodium symporter activity
RD06_RS02145	COG2031	fatty acid transporter
RD06_RS02160	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
RD06_RS02165	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RD06_RS02185	COG3181	Tripartite tricarboxylate transporter family receptor
RD06_RS02195	COG0277	FAD linked oxidase domain protein
RD06_RS02200	COG1960	acyl-CoA dehydrogenase activity
RD06_RS02205	COG1960	acyl-CoA dehydrogenase activity
RD06_RS02215	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RD06_RS02230	COG2072	flavoprotein involved in K transport
RD06_RS02235	COG0604	alcohol dehydrogenase
RD06_RS02250	COG1024	Enoyl-CoA hydratase
RD06_RS02270	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
RD06_RS02275	COG1522	sequence-specific DNA binding
RD06_RS02280	COG0183	Belongs to the thiolase family
RD06_RS02290	COG1960	acyl-CoA dehydrogenase activity
RD06_RS02335	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
RD06_RS02340	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
RD06_RS02345	COG2890	protein-(glutamine-N5) methyltransferase activity
RD06_RS02350	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
RD06_RS02360	COG3181	Tripartite tricarboxylate transporter family receptor
RD06_RS02400	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
RD06_RS02405	COG1660	Displays ATPase and GTPase activities
RD06_RS02415	COG2010	Cytochrome c
RD06_RS02415	COG1529	Aldehyde oxidase and xanthine dehydrogenase
RD06_RS02420	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
RD06_RS02430	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
RD06_RS02435	COG1137	ATPase activity
RD06_RS02450	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
RD06_RS02460	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
RD06_RS02495	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
RD06_RS02500	COG3568	Endonuclease Exonuclease Phosphatase
RD06_RS02505	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RD06_RS02535	COG0154	amidase activity
RD06_RS02545	COG1414	Transcriptional regulator
RD06_RS02560	COG1250	3-hydroxyacyl-CoA dehydrogenase
RD06_RS02560	COG1024	Enoyl-CoA hydratase
RD06_RS02570	COG2132	Multicopper oxidase
RD06_RS02600	COG1250	3-hydroxyacyl-CoA dehydrogenase
RD06_RS02625	COG1024	Enoyl-CoA hydratase
RD06_RS02630	COG1024	Enoyl-CoA hydratase
RD06_RS02635	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
RD06_RS02655	COG0601	transmembrane transport
RD06_RS02660	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RD06_RS02665	COG4608	Belongs to the ABC transporter superfamily
RD06_RS02675	COG2195	Cleaves the N-terminal amino acid of tripeptides
RD06_RS02685	COG0210	DNA helicase
RD06_RS02690	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
RD06_RS02695	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
RD06_RS02705	COG0355	proton-transporting ATP synthase activity, rotational mechanism
RD06_RS02710	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
RD06_RS02715	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
RD06_RS02720	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
RD06_RS02725	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
RD06_RS02730	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
RD06_RS02740	COG0356	it plays a direct role in the translocation of protons across the membrane
RD06_RS02765	COG1024	Enoyl-CoA hydratase
RD06_RS02770	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RD06_RS02775	COG3634	alkyl hydroperoxide reductase activity
RD06_RS02785	COG0037	tRNA processing
RD06_RS02795	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RD06_RS02800	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
RD06_RS02805	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RD06_RS02810	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
RD06_RS02815	COG2967	ApaG domain
RD06_RS02820	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
RD06_RS02825	COG0546	phosphoglycolate phosphatase activity
RD06_RS02835	COG0512	Glutamine amidotransferase of anthranilate synthase
RD06_RS02840	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
RD06_RS02845	COG0134	indole-3-glycerol-phosphate synthase activity
RD06_RS02870	COG1960	acyl-CoA dehydrogenase activity
RD06_RS02875	COG0583	DNA-binding transcription factor activity
RD06_RS02890	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RD06_RS02895	COG0259	pyridoxamine-phosphate oxidase activity
RD06_RS02905	COG2814	Major facilitator Superfamily
RD06_RS02910	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
RD06_RS02915	COG2188	Transcriptional regulator
RD06_RS02920	COG0318	PFAM AMP-dependent synthetase and ligase
RD06_RS02940	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
RD06_RS02950	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
RD06_RS02965	COG1215	transferase activity, transferring glycosyl groups
RD06_RS02975	COG0601	transmembrane transport
RD06_RS02985	COG0488	(ABC) transporter
RD06_RS03005	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
RD06_RS03010	COG2894	cell division
RD06_RS03015	COG0850	regulation of cytokinetic process
RD06_RS03020	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
RD06_RS03025	COG1271	oxidase subunit
RD06_RS03060	COG2979	Protein of unknown function (DUF533)
RD06_RS03080	COG1388	LysM domain
RD06_RS03080	COG0741	lytic transglycosylase activity
RD06_RS03085	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RD06_RS03090	COG2226	methyltransferase
RD06_RS03095	COG0328	RNA-DNA hybrid ribonuclease activity
RD06_RS03140	COG2030	dehydratase
RD06_RS03145	COG0183	Belongs to the thiolase family
RD06_RS03190	COG1960	acyl-CoA dehydrogenase activity
RD06_RS03205	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD06_RS03210	COG1028	Short-chain dehydrogenase reductase Sdr
RD06_RS03225	COG2718	Belongs to the UPF0229 family
RD06_RS03230	COG2719	SpoVR family
RD06_RS03255	COG2188	Transcriptional regulator
RD06_RS03270	COG0633	Ferredoxin
RD06_RS03280	COG0829	nickel cation binding
RD06_RS03285	COG0831	urea catabolic process
RD06_RS03295	COG0832	Belongs to the urease beta subunit family
RD06_RS03300	COG0804	urea catabolic process
RD06_RS03310	COG0830	nickel cation binding
RD06_RS03315	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
RD06_RS03335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RD06_RS03340	COG0601	transmembrane transport
RD06_RS03345	COG0747	negative chemotaxis
RD06_RS03355	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
RD06_RS03360	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RD06_RS03370	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
RD06_RS03380	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
RD06_RS03385	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
RD06_RS03390	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
RD06_RS03405	COG0438	transferase activity, transferring glycosyl groups
RD06_RS03420	COG0438	transferase activity, transferring glycosyl groups
RD06_RS03425	COG0438	transferase activity, transferring glycosyl groups
RD06_RS03430	COG0166	Belongs to the GPI family
RD06_RS03445	COG0277	FAD linked oxidase domain protein
RD06_RS03450	COG0745	RESPONSE REGULATOR receiver
RD06_RS03455	COG0642	Histidine kinase
RD06_RS03460	COG1368	sulfuric ester hydrolase activity
RD06_RS03470	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
RD06_RS03495	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
RD06_RS03505	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
RD06_RS03510	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
RD06_RS03520	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
RD06_RS03525	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
RD06_RS03530	COG0193	aminoacyl-tRNA hydrolase activity
RD06_RS03540	COG0012	GTP binding
RD06_RS03545	COG0582	viral genome integration into host DNA
RD06_RS03565	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
RD06_RS03615	COG0745	RESPONSE REGULATOR receiver
RD06_RS03630	COG1309	transcriptional regulator
RD06_RS03655	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RD06_RS03665	COG0405	Gamma-glutamyltransferase
RD06_RS03680	COG1280	lysine exporter protein (LysE YggA)
RD06_RS03740	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
RD06_RS03745	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RD06_RS03755	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
RD06_RS03760	COG0513	Belongs to the DEAD box helicase family
RD06_RS03770	COG0617	tRNA 3'-terminal CCA addition
RD06_RS03785	COG0477	Major facilitator Superfamily
RD06_RS03795	COG0583	DNA-binding transcription factor activity
RD06_RS03810	COG1950	PFAM Membrane protein of
RD06_RS03815	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
RD06_RS03830	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
RD06_RS03840	COG1560	Kdo2-lipid A biosynthetic process
RD06_RS03845	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
RD06_RS03855	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
RD06_RS03865	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
RD06_RS03875	COG0803	Belongs to the bacterial solute-binding protein 9 family
RD06_RS03895	COG0735	belongs to the Fur family
RD06_RS03900	COG0523	cobalamin synthesis protein
RD06_RS03910	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
RD06_RS03915	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
RD06_RS03925	COG2096	Adenosyltransferase
RD06_RS03940	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
RD06_RS03945	COG2084	Dehydrogenase
RD06_RS03995	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
RD06_RS04000	COG0129	dihydroxy-acid dehydratase activity
RD06_RS04005	COG4654	Cytochrome c, class I
RD06_RS04010	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
RD06_RS04060	COG1473	amidohydrolase
RD06_RS04065	COG0418	dihydroorotase activity
RD06_RS04070	COG0488	(ABC) transporter
RD06_RS04080	COG2001	Belongs to the MraZ family
RD06_RS04085	COG0275	rRNA processing
RD06_RS04090	COG3116	cell division
RD06_RS04100	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
RD06_RS04105	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
RD06_RS04110	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
RD06_RS04120	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
RD06_RS04125	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
RD06_RS04130	COG1181	Belongs to the D-alanine--D-alanine ligase family
RD06_RS04135	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
RD06_RS04145	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
RD06_RS04150	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
RD06_RS04160	COG0739	heme binding
RD06_RS04165	COG0653	protein targeting
RD06_RS04185	COG1028	Short-chain dehydrogenase reductase Sdr
RD06_RS04190	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RD06_RS04195	COG1522	sequence-specific DNA binding
RD06_RS04215	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
RD06_RS04225	COG0557	exoribonuclease II activity
RD06_RS04230	COG3150	esterase
RD06_RS04235	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
RD06_RS04240	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RD06_RS04245	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
RD06_RS04250	COG0511	ligase activity, forming carbon-carbon bonds
RD06_RS04255	COG0439	Biotin carboxylase
RD06_RS04260	COG2264	protein methyltransferase activity
RD06_RS04270	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RD06_RS04295	COG1696	Membrane protein involved in D-alanine export
RD06_RS04300	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RD06_RS04335	COG1522	sequence-specific DNA binding
RD06_RS04350	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
RD06_RS04355	COG0045	succinate-CoA ligase (ADP-forming) activity
RD06_RS04355	COG1042	CoA-binding domain protein
RD06_RS04355	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RD06_RS04365	COG1802	Transcriptional regulator
RD06_RS04370	COG3069	C4-dicarboxylate transmembrane transporter activity
RD06_RS04375	COG0513	Belongs to the DEAD box helicase family
RD06_RS04380	COG0346	lactoylglutathione lyase activity
RD06_RS04385	COG1335	isochorismatase
RD06_RS04390	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RD06_RS04395	COG1116	anion transmembrane transporter activity
RD06_RS04410	COG3028	Belongs to the UPF0307 family
RD06_RS04415	COG0312	modulator of DNA gyrase
RD06_RS04420	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
RD06_RS04425	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
RD06_RS04430	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
RD06_RS04435	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
RD06_RS04445	COG0316	Belongs to the HesB IscA family
RD06_RS04450	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
RD06_RS04465	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
RD06_RS04475	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
RD06_RS04480	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
RD06_RS04495	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
RD06_RS04495	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
RD06_RS04525	COG0583	DNA-binding transcription factor activity
RD06_RS04530	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD06_RS04565	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
RD06_RS04575	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
RD06_RS04580	COG1845	cytochrome c oxidase, subunit III
RD06_RS04585	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
RD06_RS04590	COG0640	Transcriptional regulator
RD06_RS04610	COG3220	belongs to the UPF0276 family
RD06_RS04655	COG1666	GTP binding
RD06_RS04690	COG0312	modulator of DNA gyrase
RD06_RS04695	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
RD06_RS04700	COG3210	domain, Protein
RD06_RS04700	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
RD06_RS04700	COG3064	Membrane
RD06_RS04700	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
RD06_RS04700	COG3210	domain, Protein
RD06_RS04700	COG3064	Membrane
RD06_RS04705	COG0277	FAD linked oxidase domain protein
RD06_RS04710	COG0277	FAD linked oxidase domain protein
RD06_RS04715	COG0277	FAD linked oxidase domain protein
RD06_RS04720	COG0247	lactate metabolic process
RD06_RS04725	COG2819	hydrolase of the alpha beta superfamily
RD06_RS04760	COG0583	DNA-binding transcription factor activity
RD06_RS04765	COG0482	sulfurtransferase activity
RD06_RS04770	COG0730	response to heat
RD06_RS04775	COG0625	glutathione transferase activity
RD06_RS04780	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
RD06_RS04785	COG3909	cytochrome
RD06_RS04825	COG0154	amidase activity
RD06_RS04830	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD06_RS04835	COG1024	Enoyl-CoA hydratase
RD06_RS04850	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RD06_RS04865	COG1028	Short-chain dehydrogenase reductase Sdr
RD06_RS04870	COG1414	Transcriptional regulator
RD06_RS04880	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RD06_RS04885	COG0251	oxidation-reduction process
RD06_RS04890	COG0559	Belongs to the binding-protein-dependent transport system permease family
RD06_RS04910	COG1902	pentaerythritol trinitrate reductase activity
RD06_RS04925	COG0583	DNA-binding transcription factor activity
RD06_RS04935	COG0590	tRNA wobble adenosine to inosine editing
RD06_RS04940	COG2807	transmembrane transport
RD06_RS04960	COG0154	amidase activity
RD06_RS04965	COG0307	riboflavin synthase, alpha
RD06_RS04970	COG3181	Tripartite tricarboxylate transporter family receptor
RD06_RS04975	COG1522	sequence-specific DNA binding
RD06_RS04985	COG0318	PFAM AMP-dependent synthetase and ligase
RD06_RS04995	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RD06_RS05015	COG1063	alcohol dehydrogenase
RD06_RS05040	COG1418	mRNA catabolic process
RD06_RS05045	COG1448	Aminotransferase
RD06_RS05050	COG0583	DNA-binding transcription factor activity
RD06_RS05060	COG0477	Major facilitator Superfamily
RD06_RS05065	COG1028	Short-chain dehydrogenase reductase Sdr
RD06_RS05080	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
RD06_RS05085	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
RD06_RS05090	COG0583	DNA-binding transcription factor activity
RD06_RS05130	COG1028	Short-chain dehydrogenase reductase Sdr
RD06_RS05135	COG1309	transcriptional regulator
RD06_RS05145	COG2982	Protein involved in outer membrane biogenesis
RD06_RS05150	COG2818	Glycosylase
RD06_RS05170	COG1653	transport
RD06_RS05180	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RD06_RS05185	COG3842	ATPase activity
RD06_RS05190	COG0395	ABC-type sugar transport system, permease component
RD06_RS05195	COG1175	transmembrane transport
RD06_RS05220	COG3181	Tripartite tricarboxylate transporter family receptor
RD06_RS05225	COG2186	Transcriptional regulator
RD06_RS05250	COG1454	alcohol dehydrogenase
RD06_RS05270	COG2011	ABC-type metal ion transport system permease component
RD06_RS05275	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
RD06_RS05280	COG1501	Belongs to the glycosyl hydrolase 31 family
RD06_RS05300	COG0318	PFAM AMP-dependent synthetase and ligase
RD06_RS05305	COG1473	amidohydrolase
RD06_RS05315	COG2855	membrane
RD06_RS05325	COG2239	Acts as a magnesium transporter
RD06_RS05345	COG3181	Tripartite tricarboxylate transporter family receptor
RD06_RS05355	COG1722	exodeoxyribonuclease VII activity
RD06_RS05360	COG0142	geranyltranstransferase activity
RD06_RS05365	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
RD06_RS05370	COG1469	GTP cyclohydrolase I activity
RD06_RS05375	COG0360	Binds together with S18 to 16S ribosomal RNA
RD06_RS05380	COG2965	DNA replication, synthesis of RNA primer
RD06_RS05385	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
RD06_RS05390	COG0359	binds to the 23S rRNA
RD06_RS05400	COG0305	Participates in initiation and elongation during chromosome replication
RD06_RS05410	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
RD06_RS05420	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
RD06_RS05425	COG3737	Protein of unknown function (DUF498/DUF598)
RD06_RS05430	COG0436	Aminotransferase
RD06_RS05455	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
RD06_RS05485	COG0268	Binds directly to 16S ribosomal RNA
RD06_RS05495	COG0728	peptidoglycan biosynthetic process
RD06_RS05505	COG0563	adenylate kinase activity
RD06_RS05510	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
RD06_RS05515	COG2835	tetraacyldisaccharide 4'-kinase activity
RD06_RS05520	COG1663	tetraacyldisaccharide 4'-kinase activity
RD06_RS05525	COG0848	biopolymer transport protein
RD06_RS05530	COG0811	peptide transport
RD06_RS05540	COG1570	exodeoxyribonuclease VII activity
RD06_RS05545	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
RD06_RS05550	COG0038	chloride channel
RD06_RS05555	COG0183	Belongs to the thiolase family
RD06_RS05565	COG1278	Cold shock
RD06_RS05570	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
RD06_RS05580	COG4953	penicillin-binding protein 1C
RD06_RS05585	COG0542	response to heat
RD06_RS05590	COG2995	paraquat-inducible protein a
RD06_RS05595	COG3008	intermembrane lipid transfer
RD06_RS05595	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
RD06_RS05605	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
RD06_RS05605	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
RD06_RS05605	COG0506	proline dehydrogenase activity
RD06_RS05640	COG2271	Major facilitator Superfamily
RD06_RS05645	COG1309	transcriptional regulator
RD06_RS05655	COG3468	outer membrane autotransporter barrel domain protein
RD06_RS05685	COG0477	Major facilitator Superfamily
RD06_RS05695	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
RD06_RS05700	COG1845	cytochrome c oxidase, subunit III
RD06_RS05705	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
RD06_RS05715	COG1028	Short-chain dehydrogenase reductase Sdr
RD06_RS05735	COG0789	Transcriptional regulator
RD06_RS05760	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
RD06_RS05765	COG0697	spore germination
RD06_RS05775	COG0678	peroxiredoxin activity
RD06_RS05785	COG0412	Dienelactone hydrolase
RD06_RS05795	COG0315	cyclic pyranopterin monophosphate synthase activity
RD06_RS05810	COG0521	Mo-molybdopterin cofactor biosynthetic process
RD06_RS05815	COG0303	'Molybdopterin
RD06_RS05820	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
RD06_RS05840	COG0165	Argininosuccinate lyase
RD06_RS05845	COG0668	transmembrane transport
RD06_RS05890	COG0747	negative chemotaxis
RD06_RS05895	COG0601	transmembrane transport
RD06_RS05900	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RD06_RS05905	COG1162	GTPase activity
RD06_RS05910	COG0501	Belongs to the peptidase M48B family
RD06_RS05915	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
RD06_RS05925	COG3327	negative regulation of DNA-templated transcription, initiation
RD06_RS05930	COG3396	Phenylacetate-CoA oxygenase
RD06_RS05935	COG3460	Phenylacetate-CoA oxygenase
RD06_RS05940	COG3396	Phenylacetate-CoA oxygenase
RD06_RS05945	COG2151	metal-sulfur cluster biosynthetic enzyme
RD06_RS05950	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
RD06_RS05960	COG1012	belongs to the aldehyde dehydrogenase family
RD06_RS05965	COG1024	Enoyl-CoA hydratase
RD06_RS05970	COG2050	protein possibly involved in aromatic compounds catabolism
RD06_RS05980	COG3539	Fimbrial protein
RD06_RS05995	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
RD06_RS06000	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
RD06_RS06000	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
RD06_RS06005	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
RD06_RS06010	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
RD06_RS06010	COG0047	phosphoribosylformylglycinamidine synthase activity
RD06_RS06015	COG3210	domain, Protein
RD06_RS06015	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
RD06_RS06015	COG3064	Membrane
RD06_RS06040	COG0235	Class ii aldolase
RD06_RS06045	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
RD06_RS06050	COG0720	synthase
RD06_RS06055	COG0602	queuosine metabolic process
RD06_RS06080	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RD06_RS06115	COG3181	Tripartite tricarboxylate transporter family receptor
RD06_RS06145	COG3842	ATPase activity
RD06_RS06155	COG0395	ABC-type sugar transport system, permease component
RD06_RS06185	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RD06_RS06190	COG0420	3'-5' exonuclease activity
RD06_RS06215	COG2197	response regulator
RD06_RS06240	COG0518	GMP synthase (glutamine-hydrolyzing) activity
RD06_RS06240	COG0519	Catalyzes the synthesis of GMP from XMP
RD06_RS06250	COG3550	peptidyl-serine autophosphorylation
RD06_RS06260	COG0477	Major facilitator Superfamily
RD06_RS06275	COG1228	amidohydrolase
RD06_RS06285	COG1116	anion transmembrane transporter activity
RD06_RS06290	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RD06_RS06325	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
RD06_RS06340	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
RD06_RS06370	COG2814	Major facilitator Superfamily
RD06_RS06385	COG1280	lysine exporter protein (LysE YggA)
RD06_RS06400	COG0747	negative chemotaxis
RD06_RS06405	COG0601	transmembrane transport
RD06_RS06410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RD06_RS06415	COG4172	Belongs to the ABC transporter superfamily
RD06_RS06420	COG1609	Transcriptional regulator
RD06_RS06445	COG0586	Pfam SNARE associated Golgi protein
RD06_RS06455	COG0500	methyltransferase
RD06_RS06470	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RD06_RS06480	COG0756	dUTP diphosphatase activity
RD06_RS06490	COG0291	Belongs to the bacterial ribosomal protein bL35 family
RD06_RS06495	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
RD06_RS06500	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
RD06_RS06505	COG0072	phenylalanine-tRNA ligase activity
RD06_RS06505	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RD06_RS06510	COG0776	regulation of translation
RD06_RS06580	COG0540	Belongs to the ATCase OTCase family
RD06_RS06585	COG2974	May be involved in recombination
RD06_RS06595	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD06_RS06600	COG0583	DNA-binding transcription factor activity
RD06_RS06620	COG1028	Short-chain dehydrogenase reductase Sdr
RD06_RS06635	COG3842	ATPase activity
RD06_RS06640	COG1250	3-hydroxyacyl-CoA dehydrogenase
RD06_RS06640	COG1024	Enoyl-CoA hydratase
RD06_RS06660	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
RD06_RS06665	COG2137	regulation of response to DNA damage stimulus
RD06_RS06675	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
RD06_RS06685	COG0045	succinate-CoA ligase (ADP-forming) activity
RD06_RS06690	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
RD06_RS06695	COG0861	Integral membrane protein TerC family
RD06_RS06700	COG0861	Integral membrane protein TerC family
RD06_RS06705	COG0181	hydroxymethylbilane synthase activity
RD06_RS06765	COG4964	Belongs to the GSP D family
RD06_RS06795	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
RD06_RS06805	COG0583	DNA-binding transcription factor activity
RD06_RS06815	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RD06_RS06820	COG4311	Sarcosine oxidase, delta subunit
RD06_RS06825	COG0404	The glycine cleavage system catalyzes the degradation of glycine
RD06_RS06825	COG0446	pyridine nucleotide-disulphide oxidoreductase
RD06_RS06860	COG0812	UDP-N-acetylmuramate dehydrogenase activity
RD06_RS06865	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
RD06_RS06870	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
RD06_RS06875	COG0735	belongs to the Fur family
RD06_RS06880	COG0497	DNA recombination
RD06_RS06885	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
RD06_RS06890	COG1420	regulation of RNA biosynthetic process
RD06_RS06895	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
RD06_RS06905	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
RD06_RS06915	COG0443	Heat shock 70 kDa protein
RD06_RS06925	COG0612	Peptidase, M16
RD06_RS06945	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
RD06_RS06990	COG0745	RESPONSE REGULATOR receiver
RD06_RS06995	COG2205	protein histidine kinase activity
RD06_RS07000	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
RD06_RS07005	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
RD06_RS07010	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
RD06_RS07020	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RD06_RS07035	COG1193	negative regulation of DNA recombination
RD06_RS07040	COG0492	ferredoxin-NADP+ reductase activity
RD06_RS07045	COG1674	ftsk spoiiie
RD06_RS07050	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
RD06_RS07055	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
RD06_RS07060	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
RD06_RS07085	COG3706	GGDEF domain
RD06_RS07105	COG2814	Major facilitator Superfamily
RD06_RS07135	COG3486	L-lysine 6-monooxygenase (NADPH) activity
RD06_RS07150	COG1028	Short-chain dehydrogenase reductase Sdr
RD06_RS07160	COG3022	response to hydroperoxide
RD06_RS07170	COG1289	transmembrane transporter activity
RD06_RS07175	COG3023	N-Acetylmuramoyl-L-alanine amidase
RD06_RS07185	COG0424	maF-like protein
RD06_RS07190	COG1399	metal-binding, possibly nucleic acid-binding protein
RD06_RS07195	COG0333	Belongs to the bacterial ribosomal protein bL32 family
RD06_RS07200	COG0416	fatty acid biosynthetic process
RD06_RS07205	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
RD06_RS07220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RD06_RS07225	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
RD06_RS07250	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RD06_RS07255	COG0481	GTPase activity
RD06_RS07260	COG0681	Belongs to the peptidase S26 family
RD06_RS07265	COG0571	ribonuclease III activity
RD06_RS07270	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
RD06_RS07275	COG1381	Involved in DNA repair and RecF pathway recombination
RD06_RS07285	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
RD06_RS07300	COG3181	Tripartite tricarboxylate transporter family receptor
RD06_RS07305	COG0670	Belongs to the BI1 family
RD06_RS07320	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
RD06_RS07330	COG0583	DNA-binding transcription factor activity
RD06_RS07345	COG0583	DNA-binding transcription factor activity
RD06_RS07360	COG0791	NLP P60 protein
RD06_RS07365	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RD06_RS07370	COG3193	protein, possibly involved in utilization of glycolate and propanediol
RD06_RS07380	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RD06_RS07385	COG0697	spore germination
RD06_RS07390	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
RD06_RS07405	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
RD06_RS07435	COG1446	asparaginase
RD06_RS07440	COG4172	Belongs to the ABC transporter superfamily
RD06_RS07445	COG0747	negative chemotaxis
RD06_RS07455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RD06_RS07480	COG0504	CTP synthase activity
RD06_RS07485	COG2877	3-deoxy-8-phosphooctulonate synthase activity
RD06_RS07495	COG0148	phosphopyruvate hydratase activity
RD06_RS07500	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
RD06_RS07530	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
RD06_RS07540	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RD06_RS07565	COG1981	membrane
RD06_RS07595	COG0039	L-malate dehydrogenase activity
RD06_RS07600	COG2188	Transcriptional regulator
RD06_RS07605	COG2009	succinate dehydrogenase
RD06_RS07610	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
RD06_RS07615	COG1053	succinate dehydrogenase
RD06_RS07620	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
RD06_RS07625	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
RD06_RS07630	COG0372	Belongs to the citrate synthase family
RD06_RS07650	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
RD06_RS07650	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
RD06_RS07660	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
RD06_RS07665	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
RD06_RS07680	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
RD06_RS07685	COG3842	ATPase activity
RD06_RS07690	COG1176	ABC-type spermidine putrescine transport system, permease component I
RD06_RS07695	COG1177	transmembrane transport
RD06_RS07720	COG1960	acyl-CoA dehydrogenase activity
RD06_RS07725	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
RD06_RS07730	COG0704	Plays a role in the regulation of phosphate uptake
RD06_RS07740	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
RD06_RS07745	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
RD06_RS07745	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
RD06_RS07750	COG1643	Atp-dependent helicase
RD06_RS07765	COG0438	transferase activity, transferring glycosyl groups
RD06_RS07770	COG0726	polysaccharide deacetylase
RD06_RS07775	COG0463	Glycosyl transferase, family 2
RD06_RS07780	COG0438	transferase activity, transferring glycosyl groups
RD06_RS07785	COG2194	sulfuric ester hydrolase activity
RD06_RS07810	COG0859	PFAM glycosyl transferase family 9
RD06_RS07815	COG1132	(ABC) transporter
RD06_RS07830	COG0077	Prephenate dehydratase
RD06_RS07835	COG1530	ribonuclease E activity
RD06_RS07875	COG3468	outer membrane autotransporter barrel domain protein
RD06_RS07880	COG0424	maF-like protein
RD06_RS07885	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
RD06_RS07890	COG0799	negative regulation of ribosome biogenesis
RD06_RS07895	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
RD06_RS07900	COG0408	coproporphyrinogen oxidase activity
RD06_RS07905	COG0151	Belongs to the GarS family
RD06_RS07910	COG0217	transcriptional regulatory protein
RD06_RS07915	COG0433	COG0433 Predicted ATPase
RD06_RS07920	COG1115	amino acid carrier protein
RD06_RS07925	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
RD06_RS07935	COG1012	belongs to the aldehyde dehydrogenase family
RD06_RS07960	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
RD06_RS07975	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RD06_RS07985	COG0747	negative chemotaxis
RD06_RS07995	COG0473	3-isopropylmalate dehydrogenase activity
RD06_RS08000	COG2814	Major facilitator Superfamily
RD06_RS08005	COG1566	PFAM secretion protein HlyD family protein
RD06_RS08015	COG1846	Transcriptional regulator
RD06_RS08025	COG0697	spore germination
RD06_RS08035	COG0501	Belongs to the peptidase M48B family
RD06_RS08055	COG0583	DNA-binding transcription factor activity
RD06_RS08060	COG3842	ATPase activity
RD06_RS08065	COG1178	ABC-type Fe3 transport system permease component
RD06_RS08070	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RD06_RS08075	COG1840	ABC-type Fe3 transport system, periplasmic component
RD06_RS08080	COG0492	ferredoxin-NADP+ reductase activity
RD06_RS08100	COG2233	PERMEase
RD06_RS08105	COG0840	transmembrane signaling receptor activity
RD06_RS08110	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
RD06_RS08140	COG4789	Type iii secretion
RD06_RS08205	COG4669	(LipO)protein
RD06_RS08240	COG4790	Type iii secretion
RD06_RS08245	COG4794	Type iii secretion
RD06_RS08250	COG4791	protein targeting
RD06_RS08255	COG4792	protein secretion
RD06_RS08270	COG1595	DNA-templated transcription, initiation
RD06_RS08295	COG2208	phosphoserine phosphatase activity
RD06_RS08295	COG2770	Histidine kinase
RD06_RS08305	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
RD06_RS08310	COG2172	sigma factor antagonist activity
RD06_RS08315	COG1366	Belongs to the anti-sigma-factor antagonist family
RD06_RS08320	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RD06_RS08350	COG2358	TRAP transporter, solute receptor (TAXI family
RD06_RS08355	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
RD06_RS08385	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RD06_RS08395	COG2252	PERMEase
RD06_RS08400	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
RD06_RS08410	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
RD06_RS08415	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
RD06_RS08445	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
RD06_RS08450	COG0789	Transcriptional regulator
RD06_RS08460	COG0678	peroxiredoxin activity
RD06_RS08460	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
RD06_RS08470	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
RD06_RS08475	COG0584	glycerophosphoryl diester phosphodiesterase
RD06_RS08480	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
RD06_RS08490	COG4181	ATPase activity
RD06_RS08500	COG2823	Periplasmic or secreted lipoprotein
RD06_RS08510	COG3237	CsbD-like
RD06_RS08515	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
RD06_RS08515	COG1181	Belongs to the D-alanine--D-alanine ligase family
RD06_RS08520	COG0189	ligase activity
RD06_RS08520	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
RD06_RS08540	COG2833	Protein of unknown function (DUF455)
RD06_RS08545	COG2951	lytic endotransglycosylase activity
RD06_RS08560	COG1522	sequence-specific DNA binding
RD06_RS08570	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
RD06_RS08575	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
RD06_RS08580	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
RD06_RS08585	COG0196	riboflavin kinase activity
RD06_RS08590	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
RD06_RS08590	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
RD06_RS08610	COG0210	DNA helicase
RD06_RS08615	COG4771	TonB-dependent receptor
RD06_RS08620	COG0488	(ABC) transporter
RD06_RS08625	COG2890	protein-(glutamine-N5) methyltransferase activity
RD06_RS08630	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RD06_RS08635	COG2171	N-acyltransferase activity
RD06_RS08675	COG1278	Cold shock
RD06_RS08685	COG1278	Cold shock
RD06_RS08695	COG0544	peptidyl-prolyl cis-trans isomerase activity
RD06_RS08700	COG0740	serine-type endopeptidase activity
RD06_RS08705	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
RD06_RS08710	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
RD06_RS08715	COG0583	DNA-binding transcription factor activity
RD06_RS08720	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD06_RS08735	COG1024	Enoyl-CoA hydratase
RD06_RS08745	COG0183	Belongs to the thiolase family
RD06_RS08750	COG1028	Short-chain dehydrogenase reductase Sdr
RD06_RS08755	COG1960	acyl-CoA dehydrogenase activity
RD06_RS08770	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
RD06_RS08795	COG3468	outer membrane autotransporter barrel domain protein
RD06_RS08800	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
RD06_RS08810	COG0556	nucleotide-excision repair
RD06_RS08815	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
RD06_RS08825	COG1104	cysteine desulfurase activity
RD06_RS08830	COG0822	iron-sulfur transferase activity
RD06_RS08835	COG0316	Belongs to the HesB IscA family
RD06_RS08840	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
RD06_RS08845	COG0443	Heat shock 70 kDa protein
RD06_RS08850	COG0633	Ferredoxin
RD06_RS08870	COG1024	Enoyl-CoA hydratase
RD06_RS08885	COG3395	kinase activity
RD06_RS08890	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
RD06_RS08905	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
RD06_RS08915	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RD06_RS08940	COG0747	negative chemotaxis
RD06_RS08945	COG0601	transmembrane transport
RD06_RS08950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RD06_RS08955	COG4172	Belongs to the ABC transporter superfamily
RD06_RS08960	COG0154	amidase activity
RD06_RS09005	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
RD06_RS09010	COG0425	Belongs to the sulfur carrier protein TusA family
RD06_RS09020	COG0228	four-way junction DNA binding
RD06_RS09025	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
RD06_RS09030	COG0336	Belongs to the RNA methyltransferase TrmD family
RD06_RS09035	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
RD06_RS09055	COG0642	Histidine kinase
RD06_RS09070	COG0525	valine-tRNA ligase activity
RD06_RS09075	COG0105	UTP biosynthetic process
RD06_RS09080	COG0820	rRNA (adenine-C2-)-methyltransferase activity
RD06_RS09090	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
RD06_RS09095	COG0124	histidyl-tRNA synthetase
RD06_RS09100	COG2976	Protein conserved in bacteria
RD06_RS09105	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
RD06_RS09110	COG1160	GTP binding
RD06_RS09115	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
RD06_RS09120	COG1923	regulation of RNA biosynthetic process
RD06_RS09125	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
RD06_RS09130	COG0330	HflC and HflK could
RD06_RS09135	COG0330	HflC and HflK could
RD06_RS09140	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
RD06_RS09145	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
RD06_RS09150	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
RD06_RS09155	COG0828	Belongs to the bacterial ribosomal protein bS21 family
RD06_RS09165	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
RD06_RS09195	COG0628	permease
RD06_RS09200	COG0842	Transport permease protein
RD06_RS09205	COG1131	(ABC) transporter
RD06_RS09275	COG0156	8-amino-7-oxononanoate synthase activity
RD06_RS09285	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
RD06_RS09285	COG4106	trans-aconitate 2-methyltransferase activity
RD06_RS09290	COG1380	Effector of murein hydrolase LrgA
RD06_RS09295	COG1346	cytolysis
RD06_RS09310	COG3284	Transcriptional regulator
RD06_RS09315	COG1012	belongs to the aldehyde dehydrogenase family
RD06_RS09330	COG2733	membrane
RD06_RS09335	COG0583	DNA-binding transcription factor activity
RD06_RS09340	COG0384	phenazine biosynthesis protein PhzF
RD06_RS09345	COG5507	3-demethylubiquinone-9 3-methyltransferase
RD06_RS09350	COG2169	Transcriptional regulator
RD06_RS09380	COG0659	secondary active sulfate transmembrane transporter activity
RD06_RS09405	COG1132	(ABC) transporter
RD06_RS09450	COG2207	Transcriptional regulator
RD06_RS09580	COG2346	COG2346, Truncated hemoglobins
RD06_RS09605	COG0583	DNA-binding transcription factor activity
RD06_RS09610	COG4692	amylo-alpha-1,6-glucosidase activity
RD06_RS09620	COG0183	Belongs to the thiolase family
RD06_RS09635	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD06_RS09640	COG0633	Ferredoxin
RD06_RS09650	COG1024	Enoyl-CoA hydratase
RD06_RS09660	COG4638	Rieske (2fe-2S)
RD06_RS09670	COG0559	Belongs to the binding-protein-dependent transport system permease family
RD06_RS09690	COG2224	Isocitrate lyase
RD06_RS09695	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
RD06_RS09695	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
RD06_RS09710	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
RD06_RS09715	COG0322	excinuclease ABC activity
RD06_RS09720	COG1472	Belongs to the glycosyl hydrolase 3 family
RD06_RS09725	COG0736	holo-[acyl-carrier-protein] synthase activity
RD06_RS09730	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
RD06_RS09740	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RD06_RS09745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RD06_RS09770	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
RD06_RS09785	COG2032	superoxide dismutase activity
RD06_RS09800	COG1024	Enoyl-CoA hydratase
RD06_RS09810	COG1802	Transcriptional regulator
RD06_RS09820	COG0183	Belongs to the thiolase family
RD06_RS09825	COG1942	4-Oxalocrotonate Tautomerase
RD06_RS09835	COG4176	ABC-type proline glycine betaine transport system permease component
RD06_RS09855	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
RD06_RS09860	COG2814	Major facilitator Superfamily
RD06_RS09865	COG0227	Belongs to the bacterial ribosomal protein bL28 family
RD06_RS09870	COG0267	Belongs to the bacterial ribosomal protein bL33 family
RD06_RS09900	COG2814	Major facilitator Superfamily
RD06_RS09905	COG0495	leucyl-tRNA aminoacylation
RD06_RS09920	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
RD06_RS09930	COG0154	amidase activity
RD06_RS09935	COG1250	3-hydroxyacyl-CoA dehydrogenase
RD06_RS09990	COG0427	acetyl-CoA hydrolase
RD06_RS09995	COG0583	DNA-binding transcription factor activity
RD06_RS10010	COG0730	response to heat
RD06_RS10015	COG0697	spore germination
RD06_RS10050	COG2885	chlorophyll binding
RD06_RS10075	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
RD06_RS10080	COG3384	dioxygenase
RD06_RS10095	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
RD06_RS10100	COG3474	cytochrome
RD06_RS10110	COG1595	DNA-templated transcription, initiation
RD06_RS10125	COG2204	response regulator
RD06_RS10165	COG4964	Belongs to the GSP D family
RD06_RS10215	COG1846	Transcriptional regulator
RD06_RS10220	COG4172	Belongs to the ABC transporter superfamily
RD06_RS10225	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RD06_RS10230	COG0601	transmembrane transport
RD06_RS10235	COG0747	negative chemotaxis
RD06_RS10245	COG0598	Magnesium transport protein CorA
RD06_RS10250	COG0210	DNA helicase
RD06_RS10265	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
RD06_RS10270	COG1012	belongs to the aldehyde dehydrogenase family
RD06_RS10275	COG0483	inositol monophosphate 1-phosphatase activity
RD06_RS10280	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
RD06_RS10290	COG1045	serine acetyltransferase
RD06_RS10295	COG0166	Belongs to the GPI family
RD06_RS10315	COG1846	Transcriptional regulator
RD06_RS10335	COG1649	PFAM Uncharacterised BCR, COG1649
RD06_RS10335	COG0726	polysaccharide deacetylase
RD06_RS10340	COG1215	transferase activity, transferring glycosyl groups
RD06_RS10350	COG1902	pentaerythritol trinitrate reductase activity
RD06_RS10375	COG0251	oxidation-reduction process
RD06_RS10385	COG1832	CoA-binding protein
RD06_RS10390	COG1414	Transcriptional regulator
RD06_RS10395	COG1902	pentaerythritol trinitrate reductase activity
RD06_RS10395	COG0446	pyridine nucleotide-disulphide oxidoreductase
RD06_RS10405	COG3842	ATPase activity
RD06_RS10435	COG0583	DNA-binding transcription factor activity
RD06_RS10445	COG1028	Short-chain dehydrogenase reductase Sdr
RD06_RS10450	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
RD06_RS10455	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
RD06_RS10470	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
RD06_RS10470	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
RD06_RS10475	COG1250	3-hydroxyacyl-CoA dehydrogenase
RD06_RS10500	COG0527	aspartate kinase activity
RD06_RS10505	COG0037	tRNA processing
RD06_RS10515	COG0825	malonyl-CoA metabolic process
RD06_RS10525	COG0215	cysteine-tRNA ligase activity
RD06_RS10540	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
RD06_RS10545	COG1968	undecaprenyl-diphosphatase activity
RD06_RS10550	COG1253	flavin adenine dinucleotide binding
RD06_RS10555	COG0483	inositol monophosphate 1-phosphatase activity
RD06_RS10575	COG0668	transmembrane transport
RD06_RS10600	COG0583	DNA-binding transcription factor activity
RD06_RS10625	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
RD06_RS10640	COG2831	hemolysin activation secretion protein
RD06_RS10645	COG3539	Fimbrial protein
RD06_RS10650	COG3188	usher protein
RD06_RS10655	COG3121	Chaperone
RD06_RS10665	COG3064	Membrane
RD06_RS10665	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
RD06_RS10665	COG3210	domain, Protein
RD06_RS10670	COG2197	response regulator
RD06_RS10675	COG2205	protein histidine kinase activity
RD06_RS10675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RD06_RS10685	COG4336	lyase activity
RD06_RS10710	COG3189	MarR family transcriptional regulator
RD06_RS10725	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
RD06_RS10735	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
RD06_RS10735	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
RD06_RS10745	COG0028	Belongs to the TPP enzyme family
RD06_RS10755	COG1012	belongs to the aldehyde dehydrogenase family
RD06_RS10760	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
RD06_RS10765	COG0010	Belongs to the arginase family
RD06_RS10770	COG1126	abc transporter atp-binding protein
RD06_RS10780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RD06_RS10795	COG0084	hydrolase, TatD family'
RD06_RS10800	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
RD06_RS10805	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
RD06_RS10810	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
RD06_RS10830	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RD06_RS10835	COG1959	2 iron, 2 sulfur cluster binding
RD06_RS10840	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
RD06_RS10840	COG1017	nitric oxide dioxygenase activity
RD06_RS10875	COG0488	(ABC) transporter
RD06_RS10880	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
RD06_RS10895	COG1024	Enoyl-CoA hydratase
RD06_RS10900	COG1619	proteins homologs of microcin C7 resistance protein MccF
RD06_RS10905	COG0590	tRNA wobble adenosine to inosine editing
RD06_RS10930	COG2212	antiporter activity
RD06_RS10935	COG1863	multisubunit Na H antiporter MnhE subunit
RD06_RS10940	COG0651	ATP synthesis coupled electron transport
RD06_RS10945	COG1006	Multisubunit Na H antiporter MnhC subunit
RD06_RS10950	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
RD06_RS10950	COG2111	Na H antiporter
RD06_RS10955	COG3181	Tripartite tricarboxylate transporter family receptor
RD06_RS10970	COG0583	DNA-binding transcription factor activity
RD06_RS10975	COG1028	Short-chain dehydrogenase reductase Sdr
RD06_RS11005	COG0431	NADPH-dependent FMN reductase
RD06_RS11050	COG1028	Short-chain dehydrogenase reductase Sdr
RD06_RS11055	COG0179	Fumarylacetoacetate (FAA) hydrolase
RD06_RS11085	COG0625	glutathione transferase activity
RD06_RS11090	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
RD06_RS11095	COG2944	sequence-specific DNA binding
RD06_RS11105	COG2197	response regulator
RD06_RS11130	COG3119	arylsulfatase activity
RD06_RS11160	COG0714	Associated with various cellular activities
RD06_RS11180	COG1028	Short-chain dehydrogenase reductase Sdr
RD06_RS11185	COG0861	Integral membrane protein TerC family
RD06_RS11230	COG0300	oxidoreductase activity
RD06_RS11255	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
RD06_RS11270	COG0438	transferase activity, transferring glycosyl groups
RD06_RS11305	COG0783	Belongs to the Dps family
RD06_RS11320	COG0583	DNA-binding transcription factor activity
RD06_RS11325	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
RD06_RS11340	COG0656	L-ascorbic acid biosynthetic process
RD06_RS11350	COG0583	DNA-binding transcription factor activity
RD06_RS11360	COG1840	ABC-type Fe3 transport system, periplasmic component
RD06_RS11365	COG1178	ABC-type Fe3 transport system permease component
RD06_RS11370	COG3842	ATPase activity
RD06_RS11380	COG1741	Belongs to the pirin family
RD06_RS11385	COG1741	Belongs to the pirin family
RD06_RS11390	COG0583	DNA-binding transcription factor activity
RD06_RS11395	COG2204	response regulator
RD06_RS11405	COG0174	glutamine synthetase
RD06_RS11410	COG0635	Involved in the biosynthesis of porphyrin-containing compound
RD06_RS11420	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
RD06_RS11425	COG2199	diguanylate cyclase activity
RD06_RS11425	COG2200	EAL domain
RD06_RS11450	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
RD06_RS11455	COG1561	YicC-like family, N-terminal region
RD06_RS11475	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
RD06_RS11480	COG0791	NLP P60 protein
RD06_RS11485	COG1028	Short-chain dehydrogenase reductase Sdr
RD06_RS11490	COG2863	cytochrome
RD06_RS11495	COG3258	Cytochrome c
RD06_RS11500	COG0194	GDP metabolic process
RD06_RS11505	COG1758	RNA polymerase activity
RD06_RS11510	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
RD06_RS11515	COG1126	abc transporter atp-binding protein
RD06_RS11520	COG0765	amino acid transport
RD06_RS11525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RD06_RS11535	COG1994	Peptidase M50
RD06_RS11540	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RD06_RS11545	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
RD06_RS11550	COG3539	Fimbrial protein
RD06_RS11555	COG2850	peptidyl-arginine hydroxylation
RD06_RS11560	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
RD06_RS11565	COG3360	Dodecin
RD06_RS11605	COG0009	L-threonylcarbamoyladenylate synthase
RD06_RS11610	COG2321	neutral zinc metallopeptidase
RD06_RS11630	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
RD06_RS11635	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
RD06_RS11640	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
RD06_RS11650	COG1074	ATP-dependent DNA helicase activity
RD06_RS11660	COG2814	Major facilitator Superfamily
RD06_RS11670	COG1686	Belongs to the peptidase S11 family
RD06_RS11685	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
RD06_RS11690	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
RD06_RS11695	COG4974	Belongs to the 'phage' integrase family
RD06_RS11700	COG0583	DNA-binding transcription factor activity
RD06_RS11705	COG0028	Belongs to the TPP enzyme family
RD06_RS11720	COG0028	Belongs to the TPP enzyme family
RD06_RS11725	COG1126	abc transporter atp-binding protein
RD06_RS11730	COG0765	amino acid transport
RD06_RS11745	COG1414	Transcriptional regulator
RD06_RS11750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RD06_RS11755	COG0009	L-threonylcarbamoyladenylate synthase
RD06_RS11760	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
RD06_RS11765	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
RD06_RS11770	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
RD06_RS11775	COG2944	sequence-specific DNA binding
RD06_RS11785	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
RD06_RS11840	COG1126	abc transporter atp-binding protein
RD06_RS11845	COG0765	amino acid transport
RD06_RS11850	COG0765	amino acid transport
RD06_RS11855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RD06_RS11865	COG2423	ornithine cyclodeaminase activity
RD06_RS11875	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
RD06_RS11880	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
RD06_RS11890	COG0189	ligase activity
RD06_RS11895	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
RD06_RS11900	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
RD06_RS11905	COG2197	response regulator
RD06_RS11915	COG0635	Involved in the biosynthesis of porphyrin-containing compound
RD06_RS11935	COG1289	transmembrane transporter activity
RD06_RS11945	COG3022	response to hydroperoxide
RD06_RS11960	COG0135	phosphoribosylanthranilate isomerase activity
RD06_RS11975	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
RD06_RS11980	COG0101	tRNA pseudouridine synthase activity
RD06_RS11990	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
RD06_RS11995	COG0473	3-isopropylmalate dehydrogenase activity
RD06_RS12000	COG0066	3-isopropylmalate dehydratase activity
RD06_RS12005	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
RD06_RS12015	COG1122	ATPase activity
RD06_RS12045	COG0437	4 iron, 4 sulfur cluster binding
RD06_RS12050	COG0243	molybdopterin cofactor binding
RD06_RS12050	COG3383	formate dehydrogenase (NAD+) activity
RD06_RS12080	COG0489	protein tyrosine kinase activity
RD06_RS12085	COG0746	molybdenum cofactor guanylyltransferase activity
RD06_RS12090	COG0303	'Molybdopterin
RD06_RS12095	COG1763	Mo-molybdopterin cofactor biosynthetic process
RD06_RS12105	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
RD06_RS12110	COG5001	Diguanylate cyclase
RD06_RS12130	COG3842	ATPase activity
RD06_RS12140	COG0406	alpha-ribazole phosphatase activity
RD06_RS12150	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
RD06_RS12155	COG0505	Belongs to the CarA family
RD06_RS12160	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
RD06_RS12190	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
RD06_RS12195	COG1960	acyl-CoA dehydrogenase activity
RD06_RS12205	COG2867	negative regulation of translational initiation
RD06_RS12215	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
RD06_RS12220	COG3706	GGDEF domain
RD06_RS12225	COG0330	HflC and HflK could
RD06_RS12240	COG0518	GMP synthase (glutamine-hydrolyzing) activity
RD06_RS12240	COG0519	Catalyzes the synthesis of GMP from XMP
RD06_RS12250	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
RD06_RS12255	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RD06_RS12260	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
RD06_RS12265	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
RD06_RS12275	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
RD06_RS12280	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
RD06_RS12285	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
RD06_RS12290	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
RD06_RS12295	COG0750	zinc metalloprotease
RD06_RS12300	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
RD06_RS12310	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
RD06_RS12315	COG0233	cytoplasmic translational termination
RD06_RS12320	COG0528	UMP kinase activity
RD06_RS12325	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
RD06_RS12330	COG0052	Belongs to the universal ribosomal protein uS2 family
RD06_RS12335	COG0024	Methionine aminopeptidase
RD06_RS12340	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
RD06_RS12370	COG0285	dihydrofolate synthase activity
RD06_RS12410	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
RD06_RS12420	COG1677	Flagellar hook-basal body complex protein FliE
RD06_RS12430	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
RD06_RS12440	COG1157	protein secretion by the type III secretion system
RD06_RS12465	COG1580	Controls the rotational direction of flagella during chemotaxis
RD06_RS12485	COG1338	Plays a role in the flagellum-specific transport system
RD06_RS12505	COG0840	transmembrane signaling receptor activity
RD06_RS12510	COG0840	transmembrane signaling receptor activity
RD06_RS12515	COG0840	transmembrane signaling receptor activity
RD06_RS12525	COG1256	bacterial-type flagellum assembly
RD06_RS12535	COG1706	bacterial-type flagellum-dependent cell motility
RD06_RS12540	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
RD06_RS12555	COG1749	Flagellar hook protein flgE
RD06_RS12565	COG1558	bacterial-type flagellum-dependent cell motility
RD06_RS12570	COG1815	bacterial-type flagellum-dependent cell motility
RD06_RS12610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RD06_RS12615	COG0765	amino acid transport
RD06_RS12620	COG1126	abc transporter atp-binding protein
RD06_RS12635	COG4948	Mandelate Racemase Muconate Lactonizing
RD06_RS12640	COG3181	Tripartite tricarboxylate transporter family receptor
RD06_RS12650	COG0066	3-isopropylmalate dehydratase activity
RD06_RS12665	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD06_RS12675	COG3181	Tripartite tricarboxylate transporter family receptor
RD06_RS12685	COG1802	Transcriptional regulator
RD06_RS12700	COG0583	DNA-binding transcription factor activity
RD06_RS12720	COG1695	Transcriptional regulator
RD06_RS12725	COG3568	Endonuclease Exonuclease Phosphatase
RD06_RS12730	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RD06_RS12745	COG0392	lysyltransferase activity
RD06_RS12785	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
RD06_RS12795	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
RD06_RS12805	COG1640	4-alpha-glucanotransferase
RD06_RS12820	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
RD06_RS12850	COG0667	Aldo Keto reductase
RD06_RS12865	COG2259	Doxx family
RD06_RS12895	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD06_RS12915	COG0386	Belongs to the glutathione peroxidase family
RD06_RS12920	COG0625	glutathione transferase activity
RD06_RS12935	COG0095	Lipoate-protein ligase
RD06_RS12950	COG0688	phosphatidylethanolamine metabolic process
RD06_RS12960	COG1464	Belongs to the NlpA lipoprotein family
RD06_RS12975	COG2363	Small membrane protein
RD06_RS13000	COG3842	ATPase activity
RD06_RS13005	COG0395	ABC-type sugar transport system, permease component
RD06_RS13010	COG1175	transmembrane transport
RD06_RS13015	COG1653	transport
RD06_RS13025	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
RD06_RS13040	COG0559	Belongs to the binding-protein-dependent transport system permease family
RD06_RS13060	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
RD06_RS13075	COG0697	spore germination
RD06_RS13085	COG2311	Membrane
RD06_RS13110	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
RD06_RS13120	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
RD06_RS13125	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
RD06_RS13130	COG1760	l-serine dehydratase
RD06_RS13135	COG1283	sodium-dependent phosphate transmembrane transporter activity
RD06_RS13140	COG0412	Dienelactone hydrolase
RD06_RS13155	COG1611	Belongs to the LOG family
RD06_RS13175	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
RD06_RS13180	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
RD06_RS13185	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
RD06_RS13190	COG0195	Participates in both transcription termination and antitermination
RD06_RS13190	COG2251	uridine kinase activity
RD06_RS13195	COG0779	Required for maturation of 30S ribosomal subunits
RD06_RS13200	COG1187	pseudouridine synthase activity
RD06_RS13205	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
RD06_RS13215	COG0583	DNA-binding transcription factor activity
RD06_RS13225	COG0523	cobalamin synthesis protein
RD06_RS13245	COG0625	glutathione transferase activity
RD06_RS13250	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
RD06_RS13255	COG1047	Peptidyl-prolyl cis-trans
RD06_RS13260	COG2003	Belongs to the UPF0758 family
RD06_RS13265	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
RD06_RS13270	COG3483	tryptophan 2,3-dioxygenase activity
RD06_RS13275	COG0254	rRNA binding
RD06_RS13285	COG0534	Mate efflux family protein
RD06_RS13305	COG2304	oxidoreductase activity
RD06_RS13325	COG1028	Short-chain dehydrogenase reductase Sdr
RD06_RS13330	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
RD06_RS13335	COG1562	ergosterol biosynthetic process
RD06_RS13340	COG1562	ergosterol biosynthetic process
RD06_RS13345	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
RD06_RS13345	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
RD06_RS13350	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
RD06_RS13360	COG0842	Transport permease protein
RD06_RS13365	COG1131	(ABC) transporter
RD06_RS13385	COG1477	protein flavinylation
RD06_RS13400	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
RD06_RS13415	COG5564	TIM-barrel signal transduction protein
RD06_RS13420	COG5441	Belongs to the UPF0261 family
RD06_RS13430	COG3468	outer membrane autotransporter barrel domain protein
RD06_RS13435	COG3468	outer membrane autotransporter barrel domain protein
RD06_RS13445	COG0542	response to heat
RD06_RS13450	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RD06_RS13465	COG0494	nUDIX hydrolase
RD06_RS13470	COG3530	Putative quorum-sensing-regulated virulence factor
RD06_RS13480	COG1595	DNA-templated transcription, initiation
RD06_RS13485	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RD06_RS13520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RD06_RS13525	COG0765	amino acid transport
RD06_RS13530	COG0765	amino acid transport
RD06_RS13560	COG2988	succinylglutamate desuccinylase activity
RD06_RS13585	COG3181	Tripartite tricarboxylate transporter family receptor
RD06_RS13590	COG2084	Dehydrogenase
RD06_RS13605	COG1619	proteins homologs of microcin C7 resistance protein MccF
RD06_RS13620	COG2814	Major facilitator Superfamily
RD06_RS13630	COG0583	DNA-binding transcription factor activity
RD06_RS13670	COG0672	)-iron permease
RD06_RS13685	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
RD06_RS13690	COG1028	Short-chain dehydrogenase reductase Sdr
RD06_RS13695	COG3243	poly(R)-hydroxyalkanoic acid synthase
RD06_RS13705	COG0564	pseudouridine synthase activity
RD06_RS13715	COG1199	ATP-dependent helicase activity
RD06_RS13720	COG2183	response to ionizing radiation
RD06_RS13725	COG0180	Tryptophanyl-tRNA synthetase
RD06_RS13745	COG3181	Tripartite tricarboxylate transporter family receptor
RD06_RS13755	COG0583	DNA-binding transcription factor activity
RD06_RS13760	COG1028	Short-chain dehydrogenase reductase Sdr
RD06_RS13765	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
RD06_RS13770	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RD06_RS13775	COG0508	dehydrogenase complex catalyzes the overall conversion of
RD06_RS13780	COG0567	Dehydrogenase, E1 component
RD06_RS13785	COG1297	OPT oligopeptide transporter protein
RD06_RS13790	COG1297	OPT oligopeptide transporter protein
RD06_RS13795	COG1522	sequence-specific DNA binding
RD06_RS13805	COG0281	malic enzyme
RD06_RS13805	COG0280	phosphate acetyltransferase
RD06_RS13810	COG3539	Fimbrial protein
RD06_RS13825	COG0613	PHP domain protein
RD06_RS13860	COG0084	hydrolase, TatD family'
RD06_RS13865	COG1136	(ABC) transporter
RD06_RS13880	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
RD06_RS13885	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
RD06_RS13890	COG1028	Short-chain dehydrogenase reductase Sdr
RD06_RS13895	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
RD06_RS13910	COG1022	Amp-dependent synthetase and ligase
RD06_RS13945	COG2205	protein histidine kinase activity
RD06_RS13950	COG0745	RESPONSE REGULATOR receiver
RD06_RS13955	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
RD06_RS13965	COG1295	ribonuclease BN
RD06_RS13980	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
RD06_RS14005	COG1534	Rna-binding protein
RD06_RS14010	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
RD06_RS14015	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
RD06_RS14025	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
RD06_RS14035	COG0248	Ppx GppA phosphatase
RD06_RS14060	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
RD06_RS14075	COG2732	(Barnase) inhibitor
RD06_RS14085	COG0281	malic enzyme
RD06_RS14085	COG0280	phosphate acetyltransferase
RD06_RS14095	COG0436	Aminotransferase
RD06_RS14100	COG0741	lytic transglycosylase activity
RD06_RS14105	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
RD06_RS14130	COG1648	precorrin-2 dehydrogenase activity
RD06_RS14130	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
RD06_RS14135	COG3468	outer membrane autotransporter barrel domain protein
RD06_RS14145	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
RD06_RS14150	COG2027	D-alanyl-D-alanine carboxypeptidase
RD06_RS14155	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
RD06_RS14160	COG0343	queuine tRNA-ribosyltransferase activity
RD06_RS14165	COG1862	Preprotein translocase
RD06_RS14170	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RD06_RS14175	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RD06_RS14190	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
RD06_RS14195	COG1702	phosphate starvation-inducible protein PhoH
RD06_RS14200	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
RD06_RS14205	COG4535	Mg2 and Co2 transporter CorC
RD06_RS14215	COG0667	Aldo Keto reductase
RD06_RS14240	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
RD06_RS14245	COG0745	RESPONSE REGULATOR receiver
RD06_RS14250	COG2201	protein-glutamate methylesterase activity
RD06_RS14260	COG0840	transmembrane signaling receptor activity
RD06_RS14275	COG0745	RESPONSE REGULATOR receiver
RD06_RS14310	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
RD06_RS14320	COG0739	heme binding
RD06_RS14330	COG0521	Mo-molybdopterin cofactor biosynthetic process
RD06_RS14340	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
RD06_RS14370	COG0625	glutathione transferase activity
RD06_RS14385	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
RD06_RS14390	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
RD06_RS14395	COG0126	phosphoglycerate kinase activity
RD06_RS14400	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
RD06_RS14405	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
RD06_RS14410	COG1385	rRNA (uridine-N3-)-methyltransferase activity
RD06_RS14420	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
RD06_RS14425	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RD06_RS14435	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
RD06_RS14445	COG4566	intracellular signal transduction
RD06_RS14450	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
RD06_RS14455	COG0339	signal peptide processing
RD06_RS14460	COG1999	signal sequence binding
RD06_RS14480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RD06_RS14490	COG1187	pseudouridine synthase activity
RD06_RS14495	COG3161	chorismate lyase activity
RD06_RS14500	COG2814	Major facilitator Superfamily
RD06_RS14510	COG0667	Aldo Keto reductase
RD06_RS14525	COG0335	large ribosomal subunit rRNA binding
RD06_RS14555	COG0175	sulfate reduction
RD06_RS14560	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
RD06_RS14565	COG4208	sulfate ABC transporter
RD06_RS14570	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
RD06_RS14585	COG0450	alkyl hydroperoxide reductase
RD06_RS14590	COG1960	acyl-CoA dehydrogenase activity
RD06_RS14605	COG0123	including yeast histone deacetylase and acetoin utilization protein
RD06_RS14610	COG2951	lytic endotransglycosylase activity
RD06_RS14625	COG1596	polysaccharide export
RD06_RS14625	COG1555	photosystem II stabilization
RD06_RS14630	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RD06_RS14635	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
RD06_RS14640	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
RD06_RS14660	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
RD06_RS14665	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
RD06_RS14670	COG0287	Prephenate dehydrogenase
RD06_RS14680	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
RD06_RS14695	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
RD06_RS14705	COG2814	Major facilitator Superfamily
RD06_RS14730	COG0583	DNA-binding transcription factor activity
RD06_RS14765	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
RD06_RS14780	COG0667	Aldo Keto reductase
RD06_RS14790	COG5265	(ABC) transporter
RD06_RS14840	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
RD06_RS14845	COG0439	Biotin carboxylase
RD06_RS14850	COG2188	Transcriptional regulator
RD06_RS14875	COG0511	ligase activity, forming carbon-carbon bonds
RD06_RS14885	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
RD06_RS14905	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
RD06_RS14920	COG0500	methyltransferase
RD06_RS14925	COG5265	(ABC) transporter
RD06_RS14940	COG0028	Belongs to the TPP enzyme family
RD06_RS14945	COG0440	acetolactate synthase activity
RD06_RS14950	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
RD06_RS14955	COG1183	phosphatidylcholine synthase activity
RD06_RS14965	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
RD06_RS14970	COG1185	polyribonucleotide nucleotidyltransferase activity
RD06_RS14985	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
RD06_RS15005	COG0149	triose-phosphate isomerase activity
RD06_RS15010	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
RD06_RS15020	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
RD06_RS15030	COG3799	methylaspartate ammonia-lyase activity
RD06_RS15070	COG0583	DNA-binding transcription factor activity
RD06_RS15075	COG0626	cystathionine gamma-synthase activity
RD06_RS15080	COG3608	succinylglutamate desuccinylase aspartoacylase
RD06_RS15100	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RD06_RS15120	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
RD06_RS15135	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RD06_RS15140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RD06_RS15145	COG1733	regulation of RNA biosynthetic process
RD06_RS15155	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
RD06_RS15160	COG0583	DNA-binding transcription factor activity
RD06_RS15165	COG1597	lipid kinase activity
RD06_RS15175	COG0671	phosphoesterase, PA-phosphatase related
RD06_RS15200	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
RD06_RS15205	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RD06_RS15210	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RD06_RS15215	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RD06_RS15220	COG0649	NAD binding
RD06_RS15225	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
RD06_RS15235	COG1034	ATP synthesis coupled electron transport
RD06_RS15240	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
RD06_RS15245	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RD06_RS15255	COG0713	ATP synthesis coupled electron transport
RD06_RS15270	COG1007	ATP synthesis coupled electron transport
RD06_RS15280	COG4774	siderophore transport
RD06_RS15285	COG4774	siderophore transport
RD06_RS15300	COG0028	Belongs to the TPP enzyme family
RD06_RS15305	COG3181	Tripartite tricarboxylate transporter family receptor
RD06_RS15310	COG0583	DNA-binding transcription factor activity
RD06_RS15315	COG0560	Phosphoserine phosphatase
RD06_RS15320	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
RD06_RS15325	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
RD06_RS15330	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
RD06_RS15340	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
RD06_RS15345	COG0308	aminopeptidase N
RD06_RS15365	COG0028	Belongs to the TPP enzyme family
RD06_RS15385	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RD06_RS15395	COG0318	PFAM AMP-dependent synthetase and ligase
RD06_RS15405	COG1802	Transcriptional regulator
RD06_RS15415	COG1802	Transcriptional regulator
RD06_RS15425	COG1028	Short-chain dehydrogenase reductase Sdr
RD06_RS15445	COG1126	abc transporter atp-binding protein
RD06_RS15450	COG0765	amino acid transport
RD06_RS15470	COG1538	Outer membrane efflux protein
RD06_RS15475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RD06_RS15480	COG2274	protein secretion by the type I secretion system
RD06_RS15485	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
RD06_RS15495	COG2994	toxin metabolic process
RD06_RS15510	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RD06_RS15515	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
RD06_RS15525	COG0583	DNA-binding transcription factor activity
RD06_RS15535	COG0142	geranyltranstransferase activity
RD06_RS15545	COG0261	This protein binds to 23S rRNA in the presence of protein L20
RD06_RS15550	COG0211	Belongs to the bacterial ribosomal protein bL27 family
RD06_RS15555	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
RD06_RS15560	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
RD06_RS15600	COG3712	iron ion homeostasis
RD06_RS15605	COG4774	siderophore transport
RD06_RS15610	COG2353	YceI-like domain
RD06_RS15630	COG0019	diaminopimelate decarboxylase activity
RD06_RS15650	COG0747	negative chemotaxis
RD06_RS15655	COG0601	transmembrane transport
RD06_RS15660	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RD06_RS15670	COG0154	amidase activity
RD06_RS15675	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
RD06_RS15700	COG2154	pterin-4-alpha-carbinolamine dehydratase
RD06_RS15710	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
RD06_RS15720	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
RD06_RS15725	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
RD06_RS15730	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
RD06_RS15735	COG1929	Belongs to the glycerate kinase type-1 family
RD06_RS15740	COG0469	pyruvate kinase activity
RD06_RS15745	COG0700	Nucleoside recognition
RD06_RS15775	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
RD06_RS15780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RD06_RS15795	COG0823	Involved in the tonB-independent uptake of proteins
RD06_RS15805	COG0848	biopolymer transport protein
RD06_RS15810	COG0811	peptide transport
RD06_RS15815	COG0824	Thioesterase
RD06_RS15820	COG0442	prolyl-tRNA aminoacylation
RD06_RS15825	COG0494	nUDIX hydrolase
RD06_RS15840	COG2135	peptidase activity
RD06_RS15905	COG1196	nuclear chromosome segregation
RD06_RS16045	COG1464	Belongs to the NlpA lipoprotein family
RD06_RS16075	COG4211	Belongs to the binding-protein-dependent transport system permease family
RD06_RS16085	COG0154	amidase activity
RD06_RS16090	COG0288	reversible hydration of carbon dioxide
RD06_RS16105	COG0514	ATP-dependent DNA helicase (RecQ)
RD06_RS16110	COG2255	four-way junction helicase activity
RD06_RS16125	COG0632	four-way junction helicase activity
RD06_RS16130	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
RD06_RS16150	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RD06_RS16160	COG0006	proline dipeptidase activity
RD06_RS16185	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
RD06_RS16200	COG4783	chaperone-mediated protein folding
RD06_RS16205	COG0429	hydrolase of the alpha beta-hydrolase fold
RD06_RS16235	COG0513	Belongs to the DEAD box helicase family
RD06_RS16255	COG1058	Belongs to the CinA family
RD06_RS16255	COG1546	Belongs to the CinA family
RD06_RS16260	COG1414	Transcriptional regulator
RD06_RS16280	COG0167	dihydroorotate dehydrogenase activity
RD06_RS16285	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
RD06_RS16295	COG0583	DNA-binding transcription factor activity
RD06_RS16355	COG0280	phosphate acetyltransferase
RD06_RS16355	COG0281	malic enzyme
RD06_RS16365	COG0601	transmembrane transport
RD06_RS16370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RD06_RS16375	COG4172	Belongs to the ABC transporter superfamily
RD06_RS16405	COG0640	Transcriptional regulator
RD06_RS16420	COG3135	benzoate transporter
RD06_RS16425	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
RD06_RS16430	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
RD06_RS16435	COG0742	ribosomal rna small subunit methyltransferase
RD06_RS16455	COG3639	organic phosphonate transmembrane transporter activity
RD06_RS16460	COG3639	organic phosphonate transmembrane transporter activity
RD06_RS16465	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
RD06_RS16500	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
RD06_RS16505	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
RD06_RS16515	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
RD06_RS16520	COG1546	Belongs to the CinA family
RD06_RS16520	COG1058	Belongs to the CinA family
RD06_RS16525	COG0284	orotidine-5'-phosphate decarboxylase activity
RD06_RS16530	COG1252	NADH dehydrogenase
RD06_RS16545	COG3468	outer membrane autotransporter barrel domain protein
RD06_RS16550	COG0459	protein refolding
RD06_RS16555	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
RD06_RS16575	COG1053	succinate dehydrogenase
RD06_RS16585	COG0583	DNA-binding transcription factor activity
RD06_RS16590	COG1053	succinate dehydrogenase
RD06_RS16610	COG3706	GGDEF domain
RD06_RS16645	COG1262	PFAM Formylglycine-generating sulfatase enzyme
RD06_RS16650	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
RD06_RS16660	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RD06_RS16670	COG0069	glutamate synthase activity
RD06_RS16675	COG2391	methyltransferase activity
RD06_RS16680	COG0679	Auxin Efflux Carrier
RD06_RS16705	COG0557	exoribonuclease II activity
RD06_RS16710	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RD06_RS16720	COG3128	pkhd-type hydroxylase
RD06_RS16725	COG0776	regulation of translation
RD06_RS16755	COG0642	Histidine kinase
RD06_RS16760	COG3158	transport of potassium into the cell
RD06_RS16765	COG0137	argininosuccinate synthase activity
RD06_RS16770	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
RD06_RS16775	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
RD06_RS16785	COG0583	DNA-binding transcription factor activity
RD06_RS16795	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
RD06_RS16815	COG2186	Transcriptional regulator
RD06_RS16825	COG2223	nitrite transmembrane transporter activity
RD06_RS16835	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RD06_RS16840	COG0450	alkyl hydroperoxide reductase
RD06_RS16860	COG1214	PFAM Peptidase M22, glycoprotease
RD06_RS16865	COG1573	uracil-dna glycosylase
RD06_RS16870	COG0477	Major facilitator Superfamily
RD06_RS16875	COG1196	nuclear chromosome segregation
RD06_RS16885	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
RD06_RS16890	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
RD06_RS16905	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
RD06_RS16910	COG1122	ATPase activity
RD06_RS16915	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
RD06_RS16920	COG1268	BioY protein
RD06_RS16940	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
RD06_RS16975	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
RD06_RS16980	COG2878	Part of a membrane complex involved in electron transport
RD06_RS16995	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
RD06_RS17000	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
RD06_RS17005	COG0251	oxidation-reduction process
RD06_RS17015	COG3228	Belongs to the MtfA family
RD06_RS17020	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
RD06_RS17030	COG0133	tryptophan synthase activity
RD06_RS17035	COG0159	tryptophan synthase activity
RD06_RS17040	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
RD06_RS17045	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
RD06_RS17060	COG1530	ribonuclease E activity
RD06_RS17070	COG0546	phosphoglycolate phosphatase activity
RD06_RS17075	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
RD06_RS17080	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
RD06_RS17090	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD06_RS17095	COG0583	DNA-binding transcription factor activity
RD06_RS17105	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD06_RS17130	COG0251	oxidation-reduction process
RD06_RS17135	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
RD06_RS17135	COG1017	nitric oxide dioxygenase activity
RD06_RS17140	COG2031	fatty acid transporter
RD06_RS17145	COG1012	belongs to the aldehyde dehydrogenase family
RD06_RS17150	COG1802	Transcriptional regulator
RD06_RS17160	COG1278	Cold shock
RD06_RS17165	COG0583	DNA-binding transcription factor activity
RD06_RS17185	COG0183	Belongs to the thiolase family
RD06_RS17195	COG1960	acyl-CoA dehydrogenase activity
RD06_RS17200	COG0583	DNA-binding transcription factor activity
RD06_RS17205	COG3181	Tripartite tricarboxylate transporter family receptor
RD06_RS17210	COG1024	Enoyl-CoA hydratase
RD06_RS17215	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD06_RS17220	COG1253	flavin adenine dinucleotide binding
RD06_RS17225	COG1285	pathogenesis
RD06_RS17235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RD06_RS17250	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
RD06_RS17260	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RD06_RS17270	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD06_RS17275	COG3181	Tripartite tricarboxylate transporter family receptor
RD06_RS17280	COG1960	acyl-CoA dehydrogenase activity
RD06_RS17300	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
RD06_RS17305	COG1024	Enoyl-CoA hydratase
RD06_RS17310	COG1960	acyl-CoA dehydrogenase activity
RD06_RS17330	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
RD06_RS17335	COG0022	dehydrogenase e1 component
RD06_RS17340	COG1024	Enoyl-CoA hydratase
RD06_RS17345	COG0508	dehydrogenase complex catalyzes the overall conversion of
RD06_RS17365	COG0683	leucine binding
RD06_RS17370	COG0559	Belongs to the binding-protein-dependent transport system permease family
RD06_RS17375	COG0411	ABC transporter
RD06_RS17385	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RD06_RS17400	COG3181	Tripartite tricarboxylate transporter family receptor
RD06_RS17425	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
RD06_RS17430	COG0793	Belongs to the peptidase S41A family
RD06_RS17435	COG4942	peptidase
RD06_RS17440	COG0588	phosphoglycerate mutase activity
RD06_RS17445	COG1054	Belongs to the UPF0176 family
RD06_RS17450	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
RD06_RS17455	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
RD06_RS17460	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
RD06_RS17465	COG3181	Tripartite tricarboxylate transporter family receptor
RD06_RS17480	COG2226	methyltransferase
RD06_RS17485	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
RD06_RS17500	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RD06_RS17505	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
RD06_RS17530	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
RD06_RS17555	COG1335	isochorismatase
RD06_RS17560	COG2309	aminopeptidase activity
RD06_RS17565	COG0596	Alpha beta hydrolase
RD06_RS17570	COG3473	Maleate cis-trans isomerase
RD06_RS17580	COG2068	MobA-Related Protein
RD06_RS17605	COG2204	response regulator
RD06_RS17610	COG5000	phosphorelay sensor kinase activity
RD06_RS17620	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
RD06_RS17620	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
RD06_RS17630	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
RD06_RS17650	COG0583	DNA-binding transcription factor activity
RD06_RS17665	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
RD06_RS17670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RD06_RS17675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RD06_RS17695	COG1522	sequence-specific DNA binding
RD06_RS17705	COG0242	peptide deformylase activity
RD06_RS17715	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
RD06_RS17725	COG0546	phosphoglycolate phosphatase activity
RD06_RS17745	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
RD06_RS17750	COG1942	4-Oxalocrotonate Tautomerase
RD06_RS17755	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RD06_RS17775	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
RD06_RS17795	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RD06_RS17800	COG1024	Enoyl-CoA hydratase
RD06_RS17805	COG1414	Transcriptional regulator
RD06_RS17810	COG0318	PFAM AMP-dependent synthetase and ligase
RD06_RS17815	COG3181	Tripartite tricarboxylate transporter family receptor
RD06_RS17845	COG0583	DNA-binding transcription factor activity
RD06_RS17860	COG3422	double-strand break repair
RD06_RS17865	COG0330	HflC and HflK could
RD06_RS17875	COG0251	oxidation-reduction process
RD06_RS17920	COG3723	Recombinational DNA repair protein, rece pathway
RD06_RS17955	COG0582	viral genome integration into host DNA
RD06_RS17980	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
RD06_RS17990	COG0706	membrane insertase activity
RD06_RS17995	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
RD06_RS18000	COG0594	ribonuclease P activity
RD06_RS18005	COG0230	Belongs to the bacterial ribosomal protein bL34 family
RD06_RS18010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
RD06_RS18025	COG1414	Transcriptional regulator
RD06_RS18030	COG0154	amidase activity
RD06_RS18045	COG1304	FMN binding
RD06_RS18070	COG1960	acyl-CoA dehydrogenase activity
RD06_RS18090	COG1960	acyl-CoA dehydrogenase activity
RD06_RS18100	COG0183	Belongs to the thiolase family
RD06_RS18105	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
RD06_RS18120	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
RD06_RS18125	COG3181	Tripartite tricarboxylate transporter family receptor
RD06_RS18135	COG2358	TRAP transporter, solute receptor (TAXI family
RD06_RS18145	COG1629	transport
RD06_RS18150	COG2922	Belongs to the Smg family
RD06_RS18175	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
RD06_RS18180	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RD06_RS18185	COG1028	Short-chain dehydrogenase reductase Sdr
RD06_RS18190	COG1012	belongs to the aldehyde dehydrogenase family
RD06_RS18200	COG0028	Belongs to the TPP enzyme family
RD06_RS18205	COG1522	sequence-specific DNA binding
RD06_RS18210	COG3781	membrane
RD06_RS18220	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
RD06_RS18240	COG4206	TonB-dependent receptor
RD06_RS18245	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RD06_RS18250	COG2022	thiamine diphosphate biosynthetic process
RD06_RS18255	COG0351	phosphomethylpyrimidine kinase
RD06_RS18260	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
RD06_RS18275	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
RD06_RS18285	COG0628	permease
RD06_RS18295	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
RD06_RS18305	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
RD06_RS18310	COG0049	tRNA binding
RD06_RS18315	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
RD06_RS18320	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
RD06_RS18325	COG0051	transcription antitermination factor activity, RNA binding
RD06_RS18330	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
RD06_RS18335	COG0088	Forms part of the polypeptide exit tunnel
RD06_RS18340	COG0089	rRNA binding
RD06_RS18345	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
RD06_RS18350	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
RD06_RS18355	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
RD06_RS18360	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
RD06_RS18365	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
RD06_RS18370	COG0255	Belongs to the universal ribosomal protein uL29 family
RD06_RS18375	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
RD06_RS18395	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
RD06_RS18400	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
RD06_RS18405	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
RD06_RS18410	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
RD06_RS18415	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
RD06_RS18420	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
RD06_RS18425	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
RD06_RS18430	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
RD06_RS18435	COG1841	ribosomal large subunit assembly
RD06_RS18440	COG0200	Binds to the 23S rRNA
RD06_RS18445	COG0201	protein transport
RD06_RS18450	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
RD06_RS18455	COG0257	Belongs to the bacterial ribosomal protein bL36 family
RD06_RS18460	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
RD06_RS18465	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
RD06_RS18470	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
RD06_RS18475	COG0202	RNA polymerase activity
RD06_RS18480	COG0203	ribosomal protein L17
RD06_RS18490	COG1324	tolerance protein
RD06_RS18495	COG4232	protein-disulfide reductase activity
RD06_RS18510	COG0218	Necessary for normal cell division and for the maintenance of normal septation
RD06_RS18520	COG1333	cytochrome c biogenesis protein
RD06_RS18525	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
RD06_RS18535	COG1965	Belongs to the frataxin family
RD06_RS18545	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
RD06_RS18550	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
RD06_RS18555	COG0232	Belongs to the dGTPase family. Type 2 subfamily
RD06_RS18570	COG2814	Major facilitator Superfamily
RD06_RS18575	COG0629	single-stranded DNA binding
RD06_RS18615	COG0402	S-adenosylhomocysteine deaminase activity
RD06_RS18625	COG0438	transferase activity, transferring glycosyl groups
RD06_RS18645	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RD06_RS18670	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
RD06_RS18675	COG2186	Transcriptional regulator
RD06_RS18695	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RD06_RS18700	COG1956	GAF domain-containing protein
RD06_RS18705	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RD06_RS18715	COG1652	LysM domain
RD06_RS18730	COG0220	tRNA (guanine-N7-)-methyltransferase activity
RD06_RS18745	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RD06_RS18770	COG3181	Tripartite tricarboxylate transporter family receptor
RD06_RS18785	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RD06_RS18800	COG1024	Enoyl-CoA hydratase
RD06_RS18815	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD06_RS18820	COG1309	transcriptional regulator
RD06_RS18825	COG2816	NAD+ diphosphatase activity
RD06_RS18830	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
RD06_RS18915	COG2814	Major facilitator Superfamily
RD06_RS18920	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
RD06_RS18940	COG1999	signal sequence binding
RD06_RS18945	COG0109	protoheme IX farnesyltransferase activity
RD06_RS18985	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
RD06_RS19005	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
RD06_RS19010	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
RD06_RS19020	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
RD06_RS19025	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
RD06_RS19035	COG0070	glutamate synthase
RD06_RS19035	COG0069	glutamate synthase activity
RD06_RS19035	COG0067	glutamate synthase
RD06_RS19045	COG3047	cAMP biosynthetic process
RD06_RS19055	COG1127	ABC transporter
RD06_RS19060	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
RD06_RS19065	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
RD06_RS19070	COG2853	Lipoprotein
RD06_RS19080	COG1131	(ABC) transporter
RD06_RS19085	COG0842	Transport permease protein
RD06_RS19095	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
RD06_RS19100	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
RD06_RS19105	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
RD06_RS19110	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
RD06_RS19115	COG0131	Imidazoleglycerol-phosphate dehydratase
RD06_RS19120	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
RD06_RS19125	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
RD06_RS19130	COG0107	imidazoleglycerol-phosphate synthase activity
RD06_RS19135	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
RD06_RS19140	COG0140	phosphoribosyl-ATP diphosphatase activity
RD06_RS19145	COG0537	adenosine 5'-monophosphoramidase activity
RD06_RS19150	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
RD06_RS19155	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
RD06_RS19170	COG3181	Tripartite tricarboxylate transporter family receptor
RD06_RS19205	COG3702	type iv secretory pathway
RD06_RS19210	COG3451	type IV secretory pathway VirB4
RD06_RS19225	COG3736	Type IV secretory pathway, component VirB8
RD06_RS19230	COG3504	Conjugal transfer protein
RD06_RS19235	COG2948	multi-organism process
RD06_RS19240	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
RD06_RS19250	COG0697	spore germination
RD06_RS19270	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
RD06_RS19275	COG0747	negative chemotaxis
RD06_RS19280	COG0601	transmembrane transport
RD06_RS19285	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RD06_RS19290	COG0444	Belongs to the ABC transporter superfamily
RD06_RS19300	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
RD06_RS19310	COG0494	nUDIX hydrolase
RD06_RS19345	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
RD06_RS19350	COG0237	dephospho-CoA kinase activity
RD06_RS19355	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
RD06_RS19370	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
RD06_RS19375	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
RD06_RS19385	COG0477	Major facilitator Superfamily
RD06_RS19390	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
RD06_RS19405	COG1126	abc transporter atp-binding protein
RD06_RS19410	COG0765	amino acid transport
RD06_RS19415	COG4597	amino acid ABC transporter
RD06_RS19420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RD06_RS19425	COG2884	Cell division ATP-binding protein ftsE
RD06_RS19430	COG2177	Part of the ABC transporter FtsEX involved in
RD06_RS19435	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
RD06_RS19445	COG1194	a g-specific adenine glycosylase
RD06_RS19455	COG2226	methyltransferase
RD06_RS19465	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD06_RS19470	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD06_RS19485	COG1024	Enoyl-CoA hydratase
RD06_RS19505	COG1024	Enoyl-CoA hydratase
RD06_RS19510	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD06_RS19515	COG3181	Tripartite tricarboxylate transporter family receptor
RD06_RS19525	COG0753	catalase activity
RD06_RS19530	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RD06_RS19535	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
RD06_RS19545	COG2175	clavaminate synthase activity
RD06_RS19550	COG1473	amidohydrolase
RD06_RS19555	COG4608	Belongs to the ABC transporter superfamily
RD06_RS19560	COG0444	Belongs to the ABC transporter superfamily
RD06_RS19575	COG0747	negative chemotaxis
RD06_RS19580	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
RD06_RS19615	COG0436	Aminotransferase
RD06_RS19620	COG1278	Cold shock