locus-tag	class	description
WU17_RS00005	COG0445	tRNA wobble uridine modification
WU17_RS00010	COG0357	Ribosomal RNA small subunit methyltransferase G
WU17_RS00015	COG1192	Involved in chromosome partitioning
WU17_RS00025	COG1475	DNA binding
WU17_RS00030	COG0252	asparaginase activity
WU17_RS00055	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
WU17_RS00065	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
WU17_RS00075	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
WU17_RS00080	COG0081	regulation of translation
WU17_RS00085	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
WU17_RS00090	COG0222	ribosome binding
WU17_RS00095	COG0085	RNA polymerase activity
WU17_RS00100	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
WU17_RS00140	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU17_RS00165	COG1024	Enoyl-CoA hydratase
WU17_RS00185	COG0752	glycyl-tRNA synthetase alpha subunit
WU17_RS00190	COG0751	glycine-tRNA ligase activity
WU17_RS00195	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
WU17_RS00200	COG0204	Acyl-transferase
WU17_RS00215	COG0242	peptide deformylase activity
WU17_RS00250	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
WU17_RS00255	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
WU17_RS00260	COG2813	Specifically methylates the guanine in position
WU17_RS00260	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
WU17_RS00275	COG2223	nitrite transmembrane transporter activity
WU17_RS00285	COG1794	racemase activity, acting on amino acids and derivatives
WU17_RS00290	COG1126	abc transporter atp-binding protein
WU17_RS00295	COG0765	amino acid transport
WU17_RS00300	COG0765	amino acid transport
WU17_RS00305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WU17_RS00370	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
WU17_RS00400	COG0326	Molecular chaperone. Has ATPase activity
WU17_RS00405	COG0625	glutathione transferase activity
WU17_RS00420	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
WU17_RS00425	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
WU17_RS00455	COG0438	transferase activity, transferring glycosyl groups
WU17_RS00460	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
WU17_RS00465	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
WU17_RS00495	COG0859	PFAM glycosyl transferase family 9
WU17_RS00510	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
WU17_RS00520	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
WU17_RS00525	COG1127	ABC transporter
WU17_RS00545	COG1686	Belongs to the peptidase S11 family
WU17_RS00555	COG2921	Belongs to the UPF0250 family
WU17_RS00560	COG0321	lipoyl(octanoyl) transferase activity
WU17_RS00565	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
WU17_RS00600	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
WU17_RS00610	COG0018	arginyl-trna synthetase
WU17_RS00630	COG0395	ABC-type sugar transport system, permease component
WU17_RS00635	COG1175	transmembrane transport
WU17_RS00640	COG1653	transport
WU17_RS00645	COG3842	ATPase activity
WU17_RS00650	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
WU17_RS00660	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
WU17_RS00680	COG1609	Transcriptional regulator
WU17_RS00690	COG0154	amidase activity
WU17_RS00695	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
WU17_RS00705	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
WU17_RS00715	COG0583	DNA-binding transcription factor activity
WU17_RS00730	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WU17_RS00735	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
WU17_RS00750	COG1802	Transcriptional regulator
WU17_RS00765	COG1024	Enoyl-CoA hydratase
WU17_RS00775	COG3181	Tripartite tricarboxylate transporter family receptor
WU17_RS00790	COG1984	allophanate hydrolase subunit 2
WU17_RS00795	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
WU17_RS00805	COG0583	DNA-binding transcription factor activity
WU17_RS00810	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
WU17_RS00820	COG5002	protein histidine kinase activity
WU17_RS00830	COG5002	protein histidine kinase activity
WU17_RS00835	COG0745	RESPONSE REGULATOR receiver
WU17_RS00840	COG2226	methyltransferase
WU17_RS00855	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
WU17_RS00875	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
WU17_RS00885	COG0513	Belongs to the DEAD box helicase family
WU17_RS00890	COG1280	lysine exporter protein (LysE YggA)
WU17_RS00895	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
WU17_RS00930	COG1054	Belongs to the UPF0176 family
WU17_RS00935	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WU17_RS00935	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WU17_RS00945	COG0489	protein tyrosine kinase activity
WU17_RS00960	COG0717	Belongs to the dCTP deaminase family
WU17_RS00990	COG2081	HI0933 family
WU17_RS01000	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
WU17_RS01010	COG0404	The glycine cleavage system catalyzes the degradation of glycine
WU17_RS01015	COG0509	glycine decarboxylation via glycine cleavage system
WU17_RS01020	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
WU17_RS01020	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
WU17_RS01060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
WU17_RS01075	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
WU17_RS01085	COG1414	Transcriptional regulator
WU17_RS01090	COG1028	Short-chain dehydrogenase reductase Sdr
WU17_RS01095	COG2031	fatty acid transporter
WU17_RS01100	COG1250	3-hydroxyacyl-CoA dehydrogenase
WU17_RS01110	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
WU17_RS01115	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
WU17_RS01125	COG4257	antibiotic catabolic process
WU17_RS01150	COG1012	belongs to the aldehyde dehydrogenase family
WU17_RS01155	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
WU17_RS01160	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WU17_RS01185	COG1028	Short-chain dehydrogenase reductase Sdr
WU17_RS01195	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WU17_RS01210	COG2188	Transcriptional regulator
WU17_RS01215	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
WU17_RS01240	COG0617	tRNA 3'-terminal CCA addition
WU17_RS01255	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
WU17_RS01260	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
WU17_RS01265	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
WU17_RS01270	COG0586	Pfam SNARE associated Golgi protein
WU17_RS01275	COG0860	N-Acetylmuramoyl-L-alanine amidase
WU17_RS01280	COG0802	atpase or kinase
WU17_RS01285	COG0114	fumarate hydratase activity
WU17_RS01295	COG3181	Tripartite tricarboxylate transporter family receptor
WU17_RS01305	COG0405	Gamma-glutamyltransferase
WU17_RS01310	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU17_RS01320	COG1960	acyl-CoA dehydrogenase activity
WU17_RS01345	COG1294	oxidase, subunit
WU17_RS01355	COG4988	ABC transporter
WU17_RS01360	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
WU17_RS01365	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
WU17_RS01380	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WU17_RS01410	COG2969	positive regulation of protein catabolic process
WU17_RS01415	COG0625	glutathione transferase activity
WU17_RS01420	COG2857	Cytochrome c1
WU17_RS01425	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
WU17_RS01430	COG0723	plastoquinol--plastocyanin reductase activity
WU17_RS01435	COG1970	mechanosensitive ion channel activity
WU17_RS01440	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
WU17_RS01455	COG2808	Putative FMN-binding domain
WU17_RS01460	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
WU17_RS01465	COG0747	negative chemotaxis
WU17_RS01470	COG0657	acetylesterase activity
WU17_RS01480	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
WU17_RS01485	COG2207	Transcriptional regulator
WU17_RS01490	COG0129	dihydroxy-acid dehydratase activity
WU17_RS01495	COG2814	Major facilitator Superfamily
WU17_RS01500	COG0583	DNA-binding transcription factor activity
WU17_RS01510	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
WU17_RS01580	COG1024	Enoyl-CoA hydratase
WU17_RS01585	COG1960	acyl-CoA dehydrogenase activity
WU17_RS01610	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
WU17_RS01615	COG0352	thiamine-phosphate diphosphorylase activity
WU17_RS01630	COG1678	Uncharacterized ACR, COG1678
WU17_RS01635	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
WU17_RS01640	COG0540	Belongs to the ATCase OTCase family
WU17_RS01655	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
WU17_RS01665	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
WU17_RS01700	COG1234	tRNA 3'-trailer cleavage
WU17_RS01720	COG3064	Membrane
WU17_RS01750	COG1683	Conserved Protein
WU17_RS01755	COG1120	ATPase activity
WU17_RS01760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WU17_RS01765	COG4558	Periplasmic binding protein
WU17_RS01770	COG3720	iron ion transport
WU17_RS01780	COG3712	iron ion homeostasis
WU17_RS01785	COG1595	DNA-templated transcription, initiation
WU17_RS01820	COG1802	Transcriptional regulator
WU17_RS01830	COG3069	C4-dicarboxylate transmembrane transporter activity
WU17_RS01840	COG1012	belongs to the aldehyde dehydrogenase family
WU17_RS01875	COG2860	membrane
WU17_RS01880	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
WU17_RS01885	COG0708	Exodeoxyribonuclease III
WU17_RS01890	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
WU17_RS01895	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
WU17_RS01900	COG0154	amidase activity
WU17_RS01905	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
WU17_RS01910	COG1077	Cell shape determining protein MreB Mrl
WU17_RS01915	COG1792	Involved in formation and maintenance of cell shape
WU17_RS01925	COG0768	penicillin binding
WU17_RS01930	COG0772	Belongs to the SEDS family
WU17_RS01935	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
WU17_RS01940	COG0471	metal ion transport
WU17_RS01945	COG1309	transcriptional regulator
WU17_RS01955	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
WU17_RS01970	COG2823	Periplasmic or secreted lipoprotein
WU17_RS01975	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
WU17_RS01990	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
WU17_RS02010	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU17_RS02020	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU17_RS02040	COG0492	ferredoxin-NADP+ reductase activity
WU17_RS02050	COG3181	Tripartite tricarboxylate transporter family receptor
WU17_RS02055	COG1024	Enoyl-CoA hydratase
WU17_RS02055	COG1250	3-hydroxyacyl-CoA dehydrogenase
WU17_RS02060	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU17_RS02065	COG0028	Belongs to the TPP enzyme family
WU17_RS02090	COG3181	Tripartite tricarboxylate transporter family receptor
WU17_RS02100	COG0697	spore germination
WU17_RS02130	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
WU17_RS02135	COG0463	Glycosyl transferase, family 2
WU17_RS02155	COG0786	glutamate:sodium symporter activity
WU17_RS02165	COG2031	fatty acid transporter
WU17_RS02180	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
WU17_RS02185	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WU17_RS02210	COG3181	Tripartite tricarboxylate transporter family receptor
WU17_RS02220	COG0277	FAD linked oxidase domain protein
WU17_RS02225	COG1960	acyl-CoA dehydrogenase activity
WU17_RS02230	COG1960	acyl-CoA dehydrogenase activity
WU17_RS02240	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
WU17_RS02255	COG2072	flavoprotein involved in K transport
WU17_RS02260	COG0604	alcohol dehydrogenase
WU17_RS02275	COG1024	Enoyl-CoA hydratase
WU17_RS02295	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
WU17_RS02300	COG1522	sequence-specific DNA binding
WU17_RS02305	COG0183	Belongs to the thiolase family
WU17_RS02315	COG1960	acyl-CoA dehydrogenase activity
WU17_RS02360	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
WU17_RS02365	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
WU17_RS02370	COG2890	protein-(glutamine-N5) methyltransferase activity
WU17_RS02375	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
WU17_RS02385	COG3181	Tripartite tricarboxylate transporter family receptor
WU17_RS02420	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
WU17_RS02425	COG1660	Displays ATPase and GTPase activities
WU17_RS02435	COG1529	Aldehyde oxidase and xanthine dehydrogenase
WU17_RS02435	COG2010	Cytochrome c
WU17_RS02440	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
WU17_RS02450	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
WU17_RS02455	COG1137	ATPase activity
WU17_RS02470	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
WU17_RS02480	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
WU17_RS02515	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
WU17_RS02520	COG3568	Endonuclease Exonuclease Phosphatase
WU17_RS02525	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WU17_RS02555	COG0154	amidase activity
WU17_RS02565	COG1414	Transcriptional regulator
WU17_RS02575	COG1024	Enoyl-CoA hydratase
WU17_RS02575	COG1250	3-hydroxyacyl-CoA dehydrogenase
WU17_RS02585	COG2132	Multicopper oxidase
WU17_RS02615	COG1250	3-hydroxyacyl-CoA dehydrogenase
WU17_RS02640	COG1024	Enoyl-CoA hydratase
WU17_RS02645	COG1024	Enoyl-CoA hydratase
WU17_RS02650	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
WU17_RS02670	COG0601	transmembrane transport
WU17_RS02675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WU17_RS02680	COG4172	Belongs to the ABC transporter superfamily
WU17_RS02690	COG2195	Cleaves the N-terminal amino acid of tripeptides
WU17_RS02700	COG0210	DNA helicase
WU17_RS02705	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
WU17_RS02710	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
WU17_RS02720	COG0355	proton-transporting ATP synthase activity, rotational mechanism
WU17_RS02725	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
WU17_RS02730	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
WU17_RS02735	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
WU17_RS02740	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
WU17_RS02745	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
WU17_RS02755	COG0356	it plays a direct role in the translocation of protons across the membrane
WU17_RS02780	COG1024	Enoyl-CoA hydratase
WU17_RS02785	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WU17_RS02790	COG3634	alkyl hydroperoxide reductase activity
WU17_RS02800	COG0037	tRNA processing
WU17_RS02810	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
WU17_RS02815	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
WU17_RS02820	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WU17_RS02825	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
WU17_RS02830	COG2967	ApaG domain
WU17_RS02835	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
WU17_RS02840	COG0546	phosphoglycolate phosphatase activity
WU17_RS02850	COG0512	Glutamine amidotransferase of anthranilate synthase
WU17_RS02855	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
WU17_RS02860	COG0134	indole-3-glycerol-phosphate synthase activity
WU17_RS02880	COG1960	acyl-CoA dehydrogenase activity
WU17_RS02885	COG0583	DNA-binding transcription factor activity
WU17_RS02900	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
WU17_RS02905	COG0259	pyridoxamine-phosphate oxidase activity
WU17_RS02915	COG2814	Major facilitator Superfamily
WU17_RS02920	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
WU17_RS02925	COG2188	Transcriptional regulator
WU17_RS02930	COG0318	PFAM AMP-dependent synthetase and ligase
WU17_RS02950	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
WU17_RS02960	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
WU17_RS02975	COG1215	transferase activity, transferring glycosyl groups
WU17_RS02985	COG0601	transmembrane transport
WU17_RS03000	COG0488	(ABC) transporter
WU17_RS03020	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
WU17_RS03025	COG2894	cell division
WU17_RS03030	COG0850	regulation of cytokinetic process
WU17_RS03035	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
WU17_RS03040	COG1271	oxidase subunit
WU17_RS03075	COG2979	Protein of unknown function (DUF533)
WU17_RS03095	COG1388	LysM domain
WU17_RS03095	COG0741	lytic transglycosylase activity
WU17_RS03100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WU17_RS03105	COG2226	methyltransferase
WU17_RS03110	COG0328	RNA-DNA hybrid ribonuclease activity
WU17_RS03160	COG2030	dehydratase
WU17_RS03165	COG0183	Belongs to the thiolase family
WU17_RS03210	COG1960	acyl-CoA dehydrogenase activity
WU17_RS03225	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU17_RS03230	COG1028	Short-chain dehydrogenase reductase Sdr
WU17_RS03245	COG2718	Belongs to the UPF0229 family
WU17_RS03250	COG2719	SpoVR family
WU17_RS03275	COG2188	Transcriptional regulator
WU17_RS03290	COG0633	Ferredoxin
WU17_RS03300	COG0829	nickel cation binding
WU17_RS03305	COG0831	urea catabolic process
WU17_RS03315	COG0832	Belongs to the urease beta subunit family
WU17_RS03320	COG0804	urea catabolic process
WU17_RS03330	COG0830	nickel cation binding
WU17_RS03335	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
WU17_RS03355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WU17_RS03360	COG0601	transmembrane transport
WU17_RS03365	COG0747	negative chemotaxis
WU17_RS03375	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
WU17_RS03380	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WU17_RS03390	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
WU17_RS03400	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
WU17_RS03405	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
WU17_RS03410	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
WU17_RS03425	COG0438	transferase activity, transferring glycosyl groups
WU17_RS03440	COG0438	transferase activity, transferring glycosyl groups
WU17_RS03445	COG0438	transferase activity, transferring glycosyl groups
WU17_RS03450	COG0166	Belongs to the GPI family
WU17_RS03465	COG0277	FAD linked oxidase domain protein
WU17_RS03470	COG0745	RESPONSE REGULATOR receiver
WU17_RS03475	COG0642	Histidine kinase
WU17_RS03480	COG1368	sulfuric ester hydrolase activity
WU17_RS03490	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
WU17_RS03515	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
WU17_RS03525	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
WU17_RS03530	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
WU17_RS03540	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
WU17_RS03545	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
WU17_RS03550	COG0193	aminoacyl-tRNA hydrolase activity
WU17_RS03560	COG0012	GTP binding
WU17_RS03565	COG0582	viral genome integration into host DNA
WU17_RS03590	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
WU17_RS03655	COG0745	RESPONSE REGULATOR receiver
WU17_RS03670	COG1309	transcriptional regulator
WU17_RS03700	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WU17_RS03710	COG0405	Gamma-glutamyltransferase
WU17_RS03725	COG1280	lysine exporter protein (LysE YggA)
WU17_RS03785	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
WU17_RS03790	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WU17_RS03800	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
WU17_RS03805	COG0513	Belongs to the DEAD box helicase family
WU17_RS03815	COG0617	tRNA 3'-terminal CCA addition
WU17_RS03830	COG0477	Major facilitator Superfamily
WU17_RS03840	COG0583	DNA-binding transcription factor activity
WU17_RS03855	COG1950	PFAM Membrane protein of
WU17_RS03860	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
WU17_RS03875	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
WU17_RS03885	COG1560	Kdo2-lipid A biosynthetic process
WU17_RS03890	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
WU17_RS03900	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
WU17_RS03910	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
WU17_RS03920	COG0803	Belongs to the bacterial solute-binding protein 9 family
WU17_RS03940	COG0735	belongs to the Fur family
WU17_RS03945	COG0523	cobalamin synthesis protein
WU17_RS03955	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
WU17_RS03960	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
WU17_RS03970	COG2096	Adenosyltransferase
WU17_RS03985	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
WU17_RS03990	COG2084	Dehydrogenase
WU17_RS04040	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
WU17_RS04045	COG0129	dihydroxy-acid dehydratase activity
WU17_RS04050	COG4654	Cytochrome c, class I
WU17_RS04055	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
WU17_RS04105	COG1473	amidohydrolase
WU17_RS04110	COG0418	dihydroorotase activity
WU17_RS04115	COG0488	(ABC) transporter
WU17_RS04125	COG2001	Belongs to the MraZ family
WU17_RS04130	COG0275	rRNA processing
WU17_RS04135	COG3116	cell division
WU17_RS04145	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
WU17_RS04150	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
WU17_RS04155	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
WU17_RS04165	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
WU17_RS04170	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
WU17_RS04175	COG1181	Belongs to the D-alanine--D-alanine ligase family
WU17_RS04180	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
WU17_RS04190	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
WU17_RS04195	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
WU17_RS04205	COG0739	heme binding
WU17_RS04210	COG0653	protein targeting
WU17_RS04230	COG1028	Short-chain dehydrogenase reductase Sdr
WU17_RS04235	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WU17_RS04240	COG1522	sequence-specific DNA binding
WU17_RS04260	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
WU17_RS04270	COG0557	exoribonuclease II activity
WU17_RS04275	COG3150	esterase
WU17_RS04280	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
WU17_RS04285	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
WU17_RS04290	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
WU17_RS04295	COG0511	ligase activity, forming carbon-carbon bonds
WU17_RS04300	COG0439	Biotin carboxylase
WU17_RS04305	COG2264	protein methyltransferase activity
WU17_RS04315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WU17_RS04340	COG1696	Membrane protein involved in D-alanine export
WU17_RS04345	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
WU17_RS04380	COG1522	sequence-specific DNA binding
WU17_RS04395	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
WU17_RS04400	COG1042	CoA-binding domain protein
WU17_RS04400	COG0045	succinate-CoA ligase (ADP-forming) activity
WU17_RS04400	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WU17_RS04415	COG1802	Transcriptional regulator
WU17_RS04420	COG3069	C4-dicarboxylate transmembrane transporter activity
WU17_RS04425	COG0513	Belongs to the DEAD box helicase family
WU17_RS04430	COG0346	lactoylglutathione lyase activity
WU17_RS04435	COG1335	isochorismatase
WU17_RS04440	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WU17_RS04445	COG1116	anion transmembrane transporter activity
WU17_RS04460	COG3028	Belongs to the UPF0307 family
WU17_RS04465	COG0312	modulator of DNA gyrase
WU17_RS04470	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
WU17_RS04475	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
WU17_RS04480	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
WU17_RS04485	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
WU17_RS04495	COG0316	Belongs to the HesB IscA family
WU17_RS04500	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
WU17_RS04515	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
WU17_RS04525	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
WU17_RS04530	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
WU17_RS04545	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
WU17_RS04545	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
WU17_RS04575	COG0583	DNA-binding transcription factor activity
WU17_RS04580	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU17_RS04615	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
WU17_RS04625	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
WU17_RS04630	COG1845	cytochrome c oxidase, subunit III
WU17_RS04635	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
WU17_RS04640	COG0640	Transcriptional regulator
WU17_RS04660	COG3220	belongs to the UPF0276 family
WU17_RS04705	COG1666	GTP binding
WU17_RS04740	COG0312	modulator of DNA gyrase
WU17_RS04745	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
WU17_RS04750	COG3064	Membrane
WU17_RS04750	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
WU17_RS04750	COG3210	domain, Protein
WU17_RS04750	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
WU17_RS04750	COG3064	Membrane
WU17_RS04750	COG3210	domain, Protein
WU17_RS04755	COG0277	FAD linked oxidase domain protein
WU17_RS04760	COG0277	FAD linked oxidase domain protein
WU17_RS04765	COG0277	FAD linked oxidase domain protein
WU17_RS04770	COG0247	lactate metabolic process
WU17_RS04775	COG2819	hydrolase of the alpha beta superfamily
WU17_RS04800	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
WU17_RS04820	COG0583	DNA-binding transcription factor activity
WU17_RS04825	COG0482	sulfurtransferase activity
WU17_RS04830	COG0730	response to heat
WU17_RS04835	COG0625	glutathione transferase activity
WU17_RS04840	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
WU17_RS04845	COG3909	cytochrome
WU17_RS04885	COG0154	amidase activity
WU17_RS04890	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU17_RS04895	COG1024	Enoyl-CoA hydratase
WU17_RS04910	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WU17_RS04925	COG1028	Short-chain dehydrogenase reductase Sdr
WU17_RS04930	COG1414	Transcriptional regulator
WU17_RS04940	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
WU17_RS04945	COG0251	oxidation-reduction process
WU17_RS04950	COG0559	Belongs to the binding-protein-dependent transport system permease family
WU17_RS04970	COG1902	pentaerythritol trinitrate reductase activity
WU17_RS04985	COG0583	DNA-binding transcription factor activity
WU17_RS04995	COG0590	tRNA wobble adenosine to inosine editing
WU17_RS05000	COG2807	transmembrane transport
WU17_RS05020	COG0154	amidase activity
WU17_RS05025	COG0307	riboflavin synthase, alpha
WU17_RS05030	COG3181	Tripartite tricarboxylate transporter family receptor
WU17_RS05035	COG1522	sequence-specific DNA binding
WU17_RS05045	COG0318	PFAM AMP-dependent synthetase and ligase
WU17_RS05055	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WU17_RS05075	COG1063	alcohol dehydrogenase
WU17_RS05100	COG1418	mRNA catabolic process
WU17_RS05105	COG1448	Aminotransferase
WU17_RS05110	COG0583	DNA-binding transcription factor activity
WU17_RS05120	COG0477	Major facilitator Superfamily
WU17_RS05125	COG1028	Short-chain dehydrogenase reductase Sdr
WU17_RS05140	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WU17_RS05145	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
WU17_RS05150	COG0583	DNA-binding transcription factor activity
WU17_RS05210	COG1028	Short-chain dehydrogenase reductase Sdr
WU17_RS05215	COG1309	transcriptional regulator
WU17_RS05225	COG2982	Protein involved in outer membrane biogenesis
WU17_RS05230	COG2818	Glycosylase
WU17_RS05250	COG1653	transport
WU17_RS05260	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WU17_RS05265	COG3842	ATPase activity
WU17_RS05270	COG0395	ABC-type sugar transport system, permease component
WU17_RS05275	COG1175	transmembrane transport
WU17_RS05295	COG3181	Tripartite tricarboxylate transporter family receptor
WU17_RS05300	COG2186	Transcriptional regulator
WU17_RS05330	COG1454	alcohol dehydrogenase
WU17_RS05350	COG2011	ABC-type metal ion transport system permease component
WU17_RS05355	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
WU17_RS05360	COG1501	Belongs to the glycosyl hydrolase 31 family
WU17_RS05385	COG0318	PFAM AMP-dependent synthetase and ligase
WU17_RS05390	COG1473	amidohydrolase
WU17_RS05400	COG2855	membrane
WU17_RS05410	COG2239	Acts as a magnesium transporter
WU17_RS05430	COG3181	Tripartite tricarboxylate transporter family receptor
WU17_RS05440	COG1722	exodeoxyribonuclease VII activity
WU17_RS05445	COG0142	geranyltranstransferase activity
WU17_RS05450	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
WU17_RS05455	COG1469	GTP cyclohydrolase I activity
WU17_RS05460	COG0360	Binds together with S18 to 16S ribosomal RNA
WU17_RS05465	COG2965	DNA replication, synthesis of RNA primer
WU17_RS05470	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
WU17_RS05475	COG0359	binds to the 23S rRNA
WU17_RS05485	COG0305	Participates in initiation and elongation during chromosome replication
WU17_RS05495	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
WU17_RS05500	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
WU17_RS05505	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
WU17_RS05510	COG3737	Protein of unknown function (DUF498/DUF598)
WU17_RS05515	COG0436	Aminotransferase
WU17_RS05540	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
WU17_RS05570	COG0268	Binds directly to 16S ribosomal RNA
WU17_RS05580	COG0728	peptidoglycan biosynthetic process
WU17_RS05590	COG0563	adenylate kinase activity
WU17_RS05595	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
WU17_RS05600	COG2835	tetraacyldisaccharide 4'-kinase activity
WU17_RS05605	COG1663	tetraacyldisaccharide 4'-kinase activity
WU17_RS05610	COG0848	biopolymer transport protein
WU17_RS05615	COG0811	peptide transport
WU17_RS05625	COG1570	exodeoxyribonuclease VII activity
WU17_RS05630	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
WU17_RS05635	COG0038	chloride channel
WU17_RS05640	COG0183	Belongs to the thiolase family
WU17_RS05650	COG1278	Cold shock
WU17_RS05655	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
WU17_RS05665	COG4953	penicillin-binding protein 1C
WU17_RS05670	COG0542	response to heat
WU17_RS05675	COG2995	paraquat-inducible protein a
WU17_RS05680	COG3008	intermembrane lipid transfer
WU17_RS05680	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
WU17_RS05690	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
WU17_RS05690	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
WU17_RS05690	COG0506	proline dehydrogenase activity
WU17_RS05725	COG2271	Major facilitator Superfamily
WU17_RS05730	COG1309	transcriptional regulator
WU17_RS05740	COG3468	outer membrane autotransporter barrel domain protein
WU17_RS05770	COG0477	Major facilitator Superfamily
WU17_RS05780	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
WU17_RS05785	COG1845	cytochrome c oxidase, subunit III
WU17_RS05790	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
WU17_RS05800	COG1028	Short-chain dehydrogenase reductase Sdr
WU17_RS05820	COG0789	Transcriptional regulator
WU17_RS05845	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
WU17_RS05850	COG0697	spore germination
WU17_RS05860	COG0678	peroxiredoxin activity
WU17_RS05870	COG0412	Dienelactone hydrolase
WU17_RS05880	COG0315	cyclic pyranopterin monophosphate synthase activity
WU17_RS05895	COG0521	Mo-molybdopterin cofactor biosynthetic process
WU17_RS05900	COG0303	'Molybdopterin
WU17_RS05905	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
WU17_RS05925	COG0165	Argininosuccinate lyase
WU17_RS05930	COG0668	transmembrane transport
WU17_RS05975	COG0747	negative chemotaxis
WU17_RS05980	COG0601	transmembrane transport
WU17_RS05985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WU17_RS05990	COG1162	GTPase activity
WU17_RS05995	COG0501	Belongs to the peptidase M48B family
WU17_RS06000	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
WU17_RS06010	COG3327	negative regulation of DNA-templated transcription, initiation
WU17_RS06015	COG3396	Phenylacetate-CoA oxygenase
WU17_RS06020	COG3460	Phenylacetate-CoA oxygenase
WU17_RS06025	COG3396	Phenylacetate-CoA oxygenase
WU17_RS06030	COG2151	metal-sulfur cluster biosynthetic enzyme
WU17_RS06035	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WU17_RS06045	COG1012	belongs to the aldehyde dehydrogenase family
WU17_RS06050	COG1024	Enoyl-CoA hydratase
WU17_RS06055	COG2050	protein possibly involved in aromatic compounds catabolism
WU17_RS06065	COG3539	Fimbrial protein
WU17_RS06085	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
WU17_RS06090	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
WU17_RS06090	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
WU17_RS06095	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
WU17_RS06100	COG0047	phosphoribosylformylglycinamidine synthase activity
WU17_RS06100	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
WU17_RS06105	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
WU17_RS06105	COG3210	domain, Protein
WU17_RS06105	COG3064	Membrane
WU17_RS06130	COG0235	Class ii aldolase
WU17_RS06135	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
WU17_RS06140	COG0720	synthase
WU17_RS06145	COG0602	queuosine metabolic process
WU17_RS06170	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WU17_RS06205	COG3181	Tripartite tricarboxylate transporter family receptor
WU17_RS06235	COG3842	ATPase activity
WU17_RS06245	COG0395	ABC-type sugar transport system, permease component
WU17_RS06285	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WU17_RS06290	COG0420	3'-5' exonuclease activity
WU17_RS06335	COG0519	Catalyzes the synthesis of GMP from XMP
WU17_RS06335	COG0518	GMP synthase (glutamine-hydrolyzing) activity
WU17_RS06350	COG3550	peptidyl-serine autophosphorylation
WU17_RS06360	COG0477	Major facilitator Superfamily
WU17_RS06375	COG1228	amidohydrolase
WU17_RS06385	COG1116	anion transmembrane transporter activity
WU17_RS06390	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WU17_RS06430	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
WU17_RS06450	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
WU17_RS06480	COG2814	Major facilitator Superfamily
WU17_RS06495	COG1280	lysine exporter protein (LysE YggA)
WU17_RS06510	COG0747	negative chemotaxis
WU17_RS06515	COG0601	transmembrane transport
WU17_RS06520	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WU17_RS06525	COG4172	Belongs to the ABC transporter superfamily
WU17_RS06530	COG1609	Transcriptional regulator
WU17_RS06560	COG0586	Pfam SNARE associated Golgi protein
WU17_RS06575	COG0500	methyltransferase
WU17_RS06590	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WU17_RS06600	COG0756	dUTP diphosphatase activity
WU17_RS06615	COG0291	Belongs to the bacterial ribosomal protein bL35 family
WU17_RS06620	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
WU17_RS06625	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
WU17_RS06630	COG0072	phenylalanine-tRNA ligase activity
WU17_RS06630	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WU17_RS06635	COG0776	regulation of translation
WU17_RS06705	COG0540	Belongs to the ATCase OTCase family
WU17_RS06710	COG2974	May be involved in recombination
WU17_RS06720	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU17_RS06725	COG0583	DNA-binding transcription factor activity
WU17_RS06745	COG1028	Short-chain dehydrogenase reductase Sdr
WU17_RS06760	COG3842	ATPase activity
WU17_RS06765	COG1250	3-hydroxyacyl-CoA dehydrogenase
WU17_RS06765	COG1024	Enoyl-CoA hydratase
WU17_RS06785	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
WU17_RS06790	COG2137	regulation of response to DNA damage stimulus
WU17_RS06800	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
WU17_RS06810	COG0045	succinate-CoA ligase (ADP-forming) activity
WU17_RS06815	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
WU17_RS06820	COG0861	Integral membrane protein TerC family
WU17_RS06825	COG0861	Integral membrane protein TerC family
WU17_RS06830	COG0181	hydroxymethylbilane synthase activity
WU17_RS06890	COG4964	Belongs to the GSP D family
WU17_RS06920	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
WU17_RS06930	COG0583	DNA-binding transcription factor activity
WU17_RS06945	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WU17_RS06950	COG4311	Sarcosine oxidase, delta subunit
WU17_RS06955	COG0446	pyridine nucleotide-disulphide oxidoreductase
WU17_RS06955	COG0404	The glycine cleavage system catalyzes the degradation of glycine
WU17_RS06990	COG0812	UDP-N-acetylmuramate dehydrogenase activity
WU17_RS06995	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
WU17_RS07000	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
WU17_RS07005	COG0735	belongs to the Fur family
WU17_RS07010	COG0497	DNA recombination
WU17_RS07015	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
WU17_RS07020	COG1420	regulation of RNA biosynthetic process
WU17_RS07025	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
WU17_RS07035	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
WU17_RS07045	COG0443	Heat shock 70 kDa protein
WU17_RS07055	COG0612	Peptidase, M16
WU17_RS07075	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
WU17_RS07120	COG0745	RESPONSE REGULATOR receiver
WU17_RS07130	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
WU17_RS07135	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
WU17_RS07140	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
WU17_RS07155	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
WU17_RS07175	COG1193	negative regulation of DNA recombination
WU17_RS07180	COG0492	ferredoxin-NADP+ reductase activity
WU17_RS07185	COG1674	ftsk spoiiie
WU17_RS07190	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
WU17_RS07195	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
WU17_RS07200	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
WU17_RS07225	COG3706	GGDEF domain
WU17_RS07245	COG2814	Major facilitator Superfamily
WU17_RS07275	COG3486	L-lysine 6-monooxygenase (NADPH) activity
WU17_RS07290	COG1028	Short-chain dehydrogenase reductase Sdr
WU17_RS07300	COG3022	response to hydroperoxide
WU17_RS07310	COG1289	transmembrane transporter activity
WU17_RS07330	COG0635	Involved in the biosynthesis of porphyrin-containing compound
WU17_RS07340	COG2197	response regulator
WU17_RS07345	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
WU17_RS07350	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
WU17_RS07355	COG0189	ligase activity
WU17_RS07365	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
WU17_RS07370	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
WU17_RS07380	COG1764	response to oxidative stress
WU17_RS07385	COG2423	ornithine cyclodeaminase activity
WU17_RS07395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WU17_RS07400	COG0765	amino acid transport
WU17_RS07405	COG0765	amino acid transport
WU17_RS07410	COG1126	abc transporter atp-binding protein
WU17_RS07465	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
WU17_RS07475	COG2944	sequence-specific DNA binding
WU17_RS07485	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
WU17_RS07490	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
WU17_RS07495	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
WU17_RS07500	COG0009	L-threonylcarbamoyladenylate synthase
WU17_RS07505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WU17_RS07510	COG1414	Transcriptional regulator
WU17_RS07525	COG0765	amino acid transport
WU17_RS07530	COG1126	abc transporter atp-binding protein
WU17_RS07535	COG0028	Belongs to the TPP enzyme family
WU17_RS07550	COG0028	Belongs to the TPP enzyme family
WU17_RS07555	COG0583	DNA-binding transcription factor activity
WU17_RS07560	COG4974	Belongs to the 'phage' integrase family
WU17_RS07565	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
WU17_RS07570	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
WU17_RS07585	COG1686	Belongs to the peptidase S11 family
WU17_RS07595	COG2814	Major facilitator Superfamily
WU17_RS07605	COG1074	ATP-dependent DNA helicase activity
WU17_RS07620	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
WU17_RS07625	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
WU17_RS07630	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
WU17_RS07650	COG2321	neutral zinc metallopeptidase
WU17_RS07655	COG0009	L-threonylcarbamoyladenylate synthase
WU17_RS07700	COG3360	Dodecin
WU17_RS07705	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
WU17_RS07710	COG2850	peptidyl-arginine hydroxylation
WU17_RS07715	COG3539	Fimbrial protein
WU17_RS07720	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
WU17_RS07725	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WU17_RS07745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WU17_RS07750	COG0765	amino acid transport
WU17_RS07755	COG1126	abc transporter atp-binding protein
WU17_RS07760	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
WU17_RS07765	COG1758	RNA polymerase activity
WU17_RS07770	COG0194	GDP metabolic process
WU17_RS07775	COG3258	Cytochrome c
WU17_RS07780	COG2863	cytochrome
WU17_RS07785	COG1028	Short-chain dehydrogenase reductase Sdr
WU17_RS07790	COG0791	NLP P60 protein
WU17_RS07795	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
WU17_RS07815	COG1561	YicC-like family, N-terminal region
WU17_RS07820	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
WU17_RS07835	COG0840	transmembrane signaling receptor activity
WU17_RS07840	COG2199	diguanylate cyclase activity
WU17_RS07840	COG2200	EAL domain
WU17_RS07845	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
WU17_RS07855	COG0635	Involved in the biosynthesis of porphyrin-containing compound
WU17_RS07860	COG0174	glutamine synthetase
WU17_RS07870	COG2204	response regulator
WU17_RS07875	COG0583	DNA-binding transcription factor activity
WU17_RS07880	COG1741	Belongs to the pirin family
WU17_RS07885	COG1741	Belongs to the pirin family
WU17_RS07895	COG3842	ATPase activity
WU17_RS07900	COG1178	ABC-type Fe3 transport system permease component
WU17_RS07905	COG1840	ABC-type Fe3 transport system, periplasmic component
WU17_RS07915	COG0583	DNA-binding transcription factor activity
WU17_RS07925	COG0656	L-ascorbic acid biosynthetic process
WU17_RS07940	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
WU17_RS07945	COG0583	DNA-binding transcription factor activity
WU17_RS07960	COG0783	Belongs to the Dps family
WU17_RS07980	COG0463	Glycosyl transferase, family 2
WU17_RS08000	COG0438	transferase activity, transferring glycosyl groups
WU17_RS08015	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
WU17_RS08040	COG0300	oxidoreductase activity
WU17_RS08085	COG0861	Integral membrane protein TerC family
WU17_RS08090	COG1028	Short-chain dehydrogenase reductase Sdr
WU17_RS08110	COG0714	Associated with various cellular activities
WU17_RS08145	COG3119	arylsulfatase activity
WU17_RS08170	COG2197	response regulator
WU17_RS08180	COG2944	sequence-specific DNA binding
WU17_RS08185	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
WU17_RS08190	COG0625	glutathione transferase activity
WU17_RS08220	COG0179	Fumarylacetoacetate (FAA) hydrolase
WU17_RS08225	COG1028	Short-chain dehydrogenase reductase Sdr
WU17_RS08270	COG0431	NADPH-dependent FMN reductase
WU17_RS08300	COG1028	Short-chain dehydrogenase reductase Sdr
WU17_RS08305	COG0583	DNA-binding transcription factor activity
WU17_RS08320	COG3181	Tripartite tricarboxylate transporter family receptor
WU17_RS08325	COG2111	Na H antiporter
WU17_RS08325	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
WU17_RS08330	COG1006	Multisubunit Na H antiporter MnhC subunit
WU17_RS08335	COG0651	ATP synthesis coupled electron transport
WU17_RS08340	COG1863	multisubunit Na H antiporter MnhE subunit
WU17_RS08345	COG2212	antiporter activity
WU17_RS08370	COG0590	tRNA wobble adenosine to inosine editing
WU17_RS08375	COG1619	proteins homologs of microcin C7 resistance protein MccF
WU17_RS08380	COG1024	Enoyl-CoA hydratase
WU17_RS08395	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
WU17_RS08400	COG0488	(ABC) transporter
WU17_RS08435	COG1017	nitric oxide dioxygenase activity
WU17_RS08435	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WU17_RS08440	COG1959	2 iron, 2 sulfur cluster binding
WU17_RS08445	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WU17_RS08465	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
WU17_RS08470	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
WU17_RS08475	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
WU17_RS08480	COG0084	hydrolase, TatD family'
WU17_RS08495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WU17_RS08505	COG1126	abc transporter atp-binding protein
WU17_RS08510	COG0010	Belongs to the arginase family
WU17_RS08515	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
WU17_RS08520	COG1012	belongs to the aldehyde dehydrogenase family
WU17_RS08530	COG0028	Belongs to the TPP enzyme family
WU17_RS08540	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
WU17_RS08540	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
WU17_RS08550	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
WU17_RS08565	COG3189	MarR family transcriptional regulator
WU17_RS08570	COG2010	Cytochrome c
WU17_RS08595	COG4336	lyase activity
WU17_RS08605	COG2205	protein histidine kinase activity
WU17_RS08605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WU17_RS08610	COG2197	response regulator
WU17_RS08615	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
WU17_RS08615	COG3210	domain, Protein
WU17_RS08615	COG3064	Membrane
WU17_RS08625	COG3121	Chaperone
WU17_RS08630	COG3188	usher protein
WU17_RS08635	COG3539	Fimbrial protein
WU17_RS08640	COG2831	hemolysin activation secretion protein
WU17_RS08655	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
WU17_RS08680	COG0583	DNA-binding transcription factor activity
WU17_RS08705	COG0668	transmembrane transport
WU17_RS08725	COG0483	inositol monophosphate 1-phosphatase activity
WU17_RS08730	COG1253	flavin adenine dinucleotide binding
WU17_RS08735	COG1968	undecaprenyl-diphosphatase activity
WU17_RS08740	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
WU17_RS08755	COG0215	cysteine-tRNA ligase activity
WU17_RS08765	COG0825	malonyl-CoA metabolic process
WU17_RS08775	COG0037	tRNA processing
WU17_RS08780	COG0527	aspartate kinase activity
WU17_RS08805	COG1250	3-hydroxyacyl-CoA dehydrogenase
WU17_RS08810	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
WU17_RS08810	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
WU17_RS08825	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
WU17_RS08830	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
WU17_RS08835	COG1028	Short-chain dehydrogenase reductase Sdr
WU17_RS08845	COG0583	DNA-binding transcription factor activity
WU17_RS08875	COG3842	ATPase activity
WU17_RS08885	COG1902	pentaerythritol trinitrate reductase activity
WU17_RS08885	COG0446	pyridine nucleotide-disulphide oxidoreductase
WU17_RS08890	COG1414	Transcriptional regulator
WU17_RS08895	COG1832	CoA-binding protein
WU17_RS08905	COG0251	oxidation-reduction process
WU17_RS08930	COG1902	pentaerythritol trinitrate reductase activity
WU17_RS08940	COG1215	transferase activity, transferring glycosyl groups
WU17_RS08945	COG1649	PFAM Uncharacterised BCR, COG1649
WU17_RS08945	COG0726	polysaccharide deacetylase
WU17_RS08965	COG1846	Transcriptional regulator
WU17_RS08970	COG2197	response regulator
WU17_RS08985	COG0166	Belongs to the GPI family
WU17_RS08990	COG1045	serine acetyltransferase
WU17_RS09000	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
WU17_RS09005	COG0483	inositol monophosphate 1-phosphatase activity
WU17_RS09010	COG1012	belongs to the aldehyde dehydrogenase family
WU17_RS09015	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
WU17_RS09030	COG0210	DNA helicase
WU17_RS09035	COG0598	Magnesium transport protein CorA
WU17_RS09045	COG0747	negative chemotaxis
WU17_RS09050	COG0601	transmembrane transport
WU17_RS09055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WU17_RS09060	COG4172	Belongs to the ABC transporter superfamily
WU17_RS09065	COG1846	Transcriptional regulator
WU17_RS09115	COG4964	Belongs to the GSP D family
WU17_RS09155	COG2204	response regulator
WU17_RS09170	COG1595	DNA-templated transcription, initiation
WU17_RS09180	COG3474	cytochrome
WU17_RS09185	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
WU17_RS09200	COG3384	dioxygenase
WU17_RS09205	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
WU17_RS09230	COG2885	chlorophyll binding
WU17_RS09265	COG0697	spore germination
WU17_RS09270	COG0730	response to heat
WU17_RS09290	COG0583	DNA-binding transcription factor activity
WU17_RS09295	COG0427	acetyl-CoA hydrolase
WU17_RS09350	COG1250	3-hydroxyacyl-CoA dehydrogenase
WU17_RS09355	COG0154	amidase activity
WU17_RS09365	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
WU17_RS09380	COG0495	leucyl-tRNA aminoacylation
WU17_RS09385	COG2814	Major facilitator Superfamily
WU17_RS09415	COG0267	Belongs to the bacterial ribosomal protein bL33 family
WU17_RS09420	COG0227	Belongs to the bacterial ribosomal protein bL28 family
WU17_RS09425	COG2814	Major facilitator Superfamily
WU17_RS09430	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
WU17_RS09445	COG4176	ABC-type proline glycine betaine transport system permease component
WU17_RS09455	COG1942	4-Oxalocrotonate Tautomerase
WU17_RS09460	COG0183	Belongs to the thiolase family
WU17_RS09470	COG1802	Transcriptional regulator
WU17_RS09480	COG1024	Enoyl-CoA hydratase
WU17_RS09485	COG0318	PFAM AMP-dependent synthetase and ligase
WU17_RS09490	COG0318	PFAM AMP-dependent synthetase and ligase
WU17_RS09500	COG2032	superoxide dismutase activity
WU17_RS09515	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
WU17_RS09540	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WU17_RS09545	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WU17_RS09555	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
WU17_RS09560	COG0736	holo-[acyl-carrier-protein] synthase activity
WU17_RS09565	COG1472	Belongs to the glycosyl hydrolase 3 family
WU17_RS09570	COG0322	excinuclease ABC activity
WU17_RS09575	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
WU17_RS09590	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
WU17_RS09590	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
WU17_RS09595	COG2224	Isocitrate lyase
WU17_RS09615	COG0559	Belongs to the binding-protein-dependent transport system permease family
WU17_RS09625	COG4638	Rieske (2fe-2S)
WU17_RS09635	COG1024	Enoyl-CoA hydratase
WU17_RS09645	COG0633	Ferredoxin
WU17_RS09650	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU17_RS09665	COG0183	Belongs to the thiolase family
WU17_RS09710	COG2346	COG2346, Truncated hemoglobins
WU17_RS09840	COG2207	Transcriptional regulator
WU17_RS09885	COG1132	(ABC) transporter
WU17_RS09910	COG0659	secondary active sulfate transmembrane transporter activity
WU17_RS09940	COG2169	Transcriptional regulator
WU17_RS09945	COG5507	3-demethylubiquinone-9 3-methyltransferase
WU17_RS09950	COG0384	phenazine biosynthesis protein PhzF
WU17_RS09955	COG0583	DNA-binding transcription factor activity
WU17_RS09960	COG2733	membrane
WU17_RS09975	COG1012	belongs to the aldehyde dehydrogenase family
WU17_RS09980	COG3284	Transcriptional regulator
WU17_RS10000	COG1380	Effector of murein hydrolase LrgA
WU17_RS10005	COG4106	trans-aconitate 2-methyltransferase activity
WU17_RS10005	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
WU17_RS10015	COG0156	8-amino-7-oxononanoate synthase activity
WU17_RS10095	COG1131	(ABC) transporter
WU17_RS10100	COG0842	Transport permease protein
WU17_RS10105	COG0628	permease
WU17_RS10140	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
WU17_RS10150	COG0828	Belongs to the bacterial ribosomal protein bS21 family
WU17_RS10155	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
WU17_RS10160	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
WU17_RS10165	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
WU17_RS10170	COG0330	HflC and HflK could
WU17_RS10175	COG0330	HflC and HflK could
WU17_RS10180	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
WU17_RS10185	COG1923	regulation of RNA biosynthetic process
WU17_RS10190	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
WU17_RS10195	COG1160	GTP binding
WU17_RS10200	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
WU17_RS10205	COG2976	Protein conserved in bacteria
WU17_RS10210	COG0124	histidyl-tRNA synthetase
WU17_RS10215	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
WU17_RS10225	COG0820	rRNA (adenine-C2-)-methyltransferase activity
WU17_RS10230	COG0105	UTP biosynthetic process
WU17_RS10235	COG0525	valine-tRNA ligase activity
WU17_RS10250	COG0642	Histidine kinase
WU17_RS10270	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
WU17_RS10275	COG0336	Belongs to the RNA methyltransferase TrmD family
WU17_RS10280	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
WU17_RS10285	COG0228	four-way junction DNA binding
WU17_RS10295	COG0425	Belongs to the sulfur carrier protein TusA family
WU17_RS10300	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
WU17_RS10345	COG0154	amidase activity
WU17_RS10350	COG4172	Belongs to the ABC transporter superfamily
WU17_RS10355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WU17_RS10360	COG0601	transmembrane transport
WU17_RS10365	COG0747	negative chemotaxis
WU17_RS10395	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WU17_RS10405	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
WU17_RS10420	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
WU17_RS10425	COG3395	kinase activity
WU17_RS10440	COG1024	Enoyl-CoA hydratase
WU17_RS10460	COG0633	Ferredoxin
WU17_RS10465	COG0443	Heat shock 70 kDa protein
WU17_RS10470	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
WU17_RS10475	COG0316	Belongs to the HesB IscA family
WU17_RS10480	COG0822	iron-sulfur transferase activity
WU17_RS10485	COG1104	cysteine desulfurase activity
WU17_RS10495	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
WU17_RS10500	COG0556	nucleotide-excision repair
WU17_RS10510	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
WU17_RS10515	COG3468	outer membrane autotransporter barrel domain protein
WU17_RS10545	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
WU17_RS10560	COG1960	acyl-CoA dehydrogenase activity
WU17_RS10565	COG1028	Short-chain dehydrogenase reductase Sdr
WU17_RS10570	COG0183	Belongs to the thiolase family
WU17_RS10580	COG1024	Enoyl-CoA hydratase
WU17_RS10595	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU17_RS10600	COG0583	DNA-binding transcription factor activity
WU17_RS10605	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
WU17_RS10610	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
WU17_RS10615	COG0740	serine-type endopeptidase activity
WU17_RS10620	COG0544	peptidyl-prolyl cis-trans isomerase activity
WU17_RS10640	COG1278	Cold shock
WU17_RS10675	COG2171	N-acyltransferase activity
WU17_RS10680	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
WU17_RS10685	COG2890	protein-(glutamine-N5) methyltransferase activity
WU17_RS10690	COG0488	(ABC) transporter
WU17_RS10695	COG4771	TonB-dependent receptor
WU17_RS10700	COG0210	DNA helicase
WU17_RS10720	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
WU17_RS10725	COG0196	riboflavin kinase activity
WU17_RS10730	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
WU17_RS10735	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
WU17_RS10740	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
WU17_RS10750	COG1522	sequence-specific DNA binding
WU17_RS10770	COG2951	lytic endotransglycosylase activity
WU17_RS10775	COG2833	Protein of unknown function (DUF455)
WU17_RS10795	COG0189	ligase activity
WU17_RS10795	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
WU17_RS10800	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
WU17_RS10800	COG1181	Belongs to the D-alanine--D-alanine ligase family
WU17_RS10805	COG3237	CsbD-like
WU17_RS10815	COG2823	Periplasmic or secreted lipoprotein
WU17_RS10830	COG4181	ATPase activity
WU17_RS10840	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
WU17_RS10845	COG0584	glycerophosphoryl diester phosphodiesterase
WU17_RS10850	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
WU17_RS10860	COG0678	peroxiredoxin activity
WU17_RS10860	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
WU17_RS10870	COG0789	Transcriptional regulator
WU17_RS10875	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
WU17_RS10905	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
WU17_RS10910	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
WU17_RS10920	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
WU17_RS10925	COG2252	PERMEase
WU17_RS10935	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
WU17_RS10965	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
WU17_RS10970	COG2358	TRAP transporter, solute receptor (TAXI family
WU17_RS11000	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WU17_RS11005	COG1366	Belongs to the anti-sigma-factor antagonist family
WU17_RS11010	COG2172	sigma factor antagonist activity
WU17_RS11015	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
WU17_RS11025	COG2770	Histidine kinase
WU17_RS11025	COG2208	phosphoserine phosphatase activity
WU17_RS11050	COG1595	DNA-templated transcription, initiation
WU17_RS11065	COG4792	protein secretion
WU17_RS11070	COG4791	protein targeting
WU17_RS11075	COG4794	Type iii secretion
WU17_RS11080	COG4790	Type iii secretion
WU17_RS11115	COG4669	(LipO)protein
WU17_RS11180	COG4789	Type iii secretion
WU17_RS11210	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
WU17_RS11215	COG0840	transmembrane signaling receptor activity
WU17_RS11220	COG2233	PERMEase
WU17_RS11240	COG0492	ferredoxin-NADP+ reductase activity
WU17_RS11245	COG1840	ABC-type Fe3 transport system, periplasmic component
WU17_RS11250	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
WU17_RS11255	COG1178	ABC-type Fe3 transport system permease component
WU17_RS11260	COG3842	ATPase activity
WU17_RS11265	COG0583	DNA-binding transcription factor activity
WU17_RS11285	COG0501	Belongs to the peptidase M48B family
WU17_RS11295	COG0697	spore germination
WU17_RS11305	COG1846	Transcriptional regulator
WU17_RS11315	COG1566	PFAM secretion protein HlyD family protein
WU17_RS11320	COG2814	Major facilitator Superfamily
WU17_RS11325	COG0473	3-isopropylmalate dehydrogenase activity
WU17_RS11335	COG0747	negative chemotaxis
WU17_RS11345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WU17_RS11360	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
WU17_RS11385	COG1012	belongs to the aldehyde dehydrogenase family
WU17_RS11395	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
WU17_RS11400	COG1115	amino acid carrier protein
WU17_RS11405	COG0433	COG0433 Predicted ATPase
WU17_RS11410	COG0217	transcriptional regulatory protein
WU17_RS11415	COG0151	Belongs to the GarS family
WU17_RS11420	COG0408	coproporphyrinogen oxidase activity
WU17_RS11425	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
WU17_RS11430	COG0799	negative regulation of ribosome biogenesis
WU17_RS11435	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
WU17_RS11440	COG0424	maF-like protein
WU17_RS11445	COG3468	outer membrane autotransporter barrel domain protein
WU17_RS11485	COG1530	ribonuclease E activity
WU17_RS11490	COG0077	Prephenate dehydratase
WU17_RS11505	COG1132	(ABC) transporter
WU17_RS11510	COG0859	PFAM glycosyl transferase family 9
WU17_RS11535	COG2194	sulfuric ester hydrolase activity
WU17_RS11540	COG0438	transferase activity, transferring glycosyl groups
WU17_RS11545	COG0463	Glycosyl transferase, family 2
WU17_RS11550	COG0726	polysaccharide deacetylase
WU17_RS11555	COG0438	transferase activity, transferring glycosyl groups
WU17_RS11570	COG1643	Atp-dependent helicase
WU17_RS11575	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
WU17_RS11575	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
WU17_RS11580	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
WU17_RS11590	COG0704	Plays a role in the regulation of phosphate uptake
WU17_RS11595	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
WU17_RS11600	COG1960	acyl-CoA dehydrogenase activity
WU17_RS11625	COG1177	transmembrane transport
WU17_RS11630	COG1176	ABC-type spermidine putrescine transport system, permease component I
WU17_RS11635	COG3842	ATPase activity
WU17_RS11640	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
WU17_RS11655	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
WU17_RS11660	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
WU17_RS11670	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
WU17_RS11670	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
WU17_RS11690	COG0372	Belongs to the citrate synthase family
WU17_RS11695	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
WU17_RS11700	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
WU17_RS11705	COG1053	succinate dehydrogenase
WU17_RS11710	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
WU17_RS11715	COG2009	succinate dehydrogenase
WU17_RS11720	COG2188	Transcriptional regulator
WU17_RS11725	COG0039	L-malate dehydrogenase activity
WU17_RS11755	COG1981	membrane
WU17_RS11780	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
WU17_RS11790	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
WU17_RS11820	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
WU17_RS11825	COG0148	phosphopyruvate hydratase activity
WU17_RS11835	COG2877	3-deoxy-8-phosphooctulonate synthase activity
WU17_RS11840	COG0504	CTP synthase activity
WU17_RS11865	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WU17_RS11875	COG0747	negative chemotaxis
WU17_RS11880	COG4172	Belongs to the ABC transporter superfamily
WU17_RS11885	COG1446	asparaginase
WU17_RS11915	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
WU17_RS11930	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
WU17_RS11935	COG0697	spore germination
WU17_RS11940	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
WU17_RS11950	COG3193	protein, possibly involved in utilization of glycolate and propanediol
WU17_RS11955	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
WU17_RS11960	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
WU17_RS11965	COG0791	NLP P60 protein
WU17_RS11980	COG0583	DNA-binding transcription factor activity
WU17_RS11995	COG0583	DNA-binding transcription factor activity
WU17_RS12005	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
WU17_RS12020	COG0670	Belongs to the BI1 family
WU17_RS12025	COG3181	Tripartite tricarboxylate transporter family receptor
WU17_RS12035	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
WU17_RS12045	COG1381	Involved in DNA repair and RecF pathway recombination
WU17_RS12050	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
WU17_RS12055	COG0571	ribonuclease III activity
WU17_RS12060	COG0681	Belongs to the peptidase S26 family
WU17_RS12065	COG0481	GTPase activity
WU17_RS12070	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WU17_RS12095	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
WU17_RS12100	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
WU17_RS12115	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
WU17_RS12120	COG0416	fatty acid biosynthetic process
WU17_RS12125	COG0333	Belongs to the bacterial ribosomal protein bL32 family
WU17_RS12130	COG1399	metal-binding, possibly nucleic acid-binding protein
WU17_RS12135	COG0424	maF-like protein
WU17_RS12145	COG3023	N-Acetylmuramoyl-L-alanine amidase
WU17_RS12160	COG0135	phosphoribosylanthranilate isomerase activity
WU17_RS12175	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
WU17_RS12180	COG0101	tRNA pseudouridine synthase activity
WU17_RS12190	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
WU17_RS12195	COG0473	3-isopropylmalate dehydrogenase activity
WU17_RS12200	COG0066	3-isopropylmalate dehydratase activity
WU17_RS12205	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
WU17_RS12215	COG1122	ATPase activity
WU17_RS12245	COG0437	4 iron, 4 sulfur cluster binding
WU17_RS12250	COG3383	formate dehydrogenase (NAD+) activity
WU17_RS12250	COG0243	molybdopterin cofactor binding
WU17_RS12280	COG0489	protein tyrosine kinase activity
WU17_RS12285	COG0746	molybdenum cofactor guanylyltransferase activity
WU17_RS12290	COG0303	'Molybdopterin
WU17_RS12295	COG1763	Mo-molybdopterin cofactor biosynthetic process
WU17_RS12305	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
WU17_RS12310	COG5001	Diguanylate cyclase
WU17_RS12330	COG3842	ATPase activity
WU17_RS12340	COG0406	alpha-ribazole phosphatase activity
WU17_RS12350	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
WU17_RS12355	COG0505	Belongs to the CarA family
WU17_RS12360	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
WU17_RS12390	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
WU17_RS12395	COG1960	acyl-CoA dehydrogenase activity
WU17_RS12405	COG2867	negative regulation of translational initiation
WU17_RS12415	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
WU17_RS12420	COG3706	GGDEF domain
WU17_RS12425	COG0330	HflC and HflK could
WU17_RS12440	COG0519	Catalyzes the synthesis of GMP from XMP
WU17_RS12440	COG0518	GMP synthase (glutamine-hydrolyzing) activity
WU17_RS12450	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
WU17_RS12455	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
WU17_RS12460	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
WU17_RS12465	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
WU17_RS12475	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
WU17_RS12480	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
WU17_RS12485	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
WU17_RS12490	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
WU17_RS12495	COG0750	zinc metalloprotease
WU17_RS12500	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
WU17_RS12510	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
WU17_RS12515	COG0233	cytoplasmic translational termination
WU17_RS12520	COG0528	UMP kinase activity
WU17_RS12525	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
WU17_RS12530	COG0052	Belongs to the universal ribosomal protein uS2 family
WU17_RS12535	COG0024	Methionine aminopeptidase
WU17_RS12540	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
WU17_RS12570	COG0285	dihydrofolate synthase activity
WU17_RS12605	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
WU17_RS12615	COG1677	Flagellar hook-basal body complex protein FliE
WU17_RS12625	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
WU17_RS12635	COG1157	protein secretion by the type III secretion system
WU17_RS12660	COG1580	Controls the rotational direction of flagella during chemotaxis
WU17_RS12680	COG1338	Plays a role in the flagellum-specific transport system
WU17_RS12700	COG0840	transmembrane signaling receptor activity
WU17_RS12705	COG0840	transmembrane signaling receptor activity
WU17_RS12710	COG0840	transmembrane signaling receptor activity
WU17_RS12720	COG1256	bacterial-type flagellum assembly
WU17_RS12730	COG1706	bacterial-type flagellum-dependent cell motility
WU17_RS12735	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
WU17_RS12750	COG1749	Flagellar hook protein flgE
WU17_RS12760	COG1558	bacterial-type flagellum-dependent cell motility
WU17_RS12765	COG1815	bacterial-type flagellum-dependent cell motility
WU17_RS12805	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WU17_RS12810	COG0765	amino acid transport
WU17_RS12815	COG1126	abc transporter atp-binding protein
WU17_RS12830	COG4948	Mandelate Racemase Muconate Lactonizing
WU17_RS12835	COG3181	Tripartite tricarboxylate transporter family receptor
WU17_RS12845	COG0066	3-isopropylmalate dehydratase activity
WU17_RS12860	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU17_RS12870	COG3181	Tripartite tricarboxylate transporter family receptor
WU17_RS12880	COG1802	Transcriptional regulator
WU17_RS12895	COG0583	DNA-binding transcription factor activity
WU17_RS12915	COG1695	Transcriptional regulator
WU17_RS12925	COG3568	Endonuclease Exonuclease Phosphatase
WU17_RS12930	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WU17_RS12945	COG0392	lysyltransferase activity
WU17_RS12985	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
WU17_RS12995	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
WU17_RS13015	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
WU17_RS13045	COG0667	Aldo Keto reductase
WU17_RS13060	COG2259	Doxx family
WU17_RS13095	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU17_RS13115	COG0386	Belongs to the glutathione peroxidase family
WU17_RS13120	COG0625	glutathione transferase activity
WU17_RS13145	COG0688	phosphatidylethanolamine metabolic process
WU17_RS13155	COG1464	Belongs to the NlpA lipoprotein family
WU17_RS13170	COG2363	Small membrane protein
WU17_RS13195	COG3842	ATPase activity
WU17_RS13200	COG0395	ABC-type sugar transport system, permease component
WU17_RS13205	COG1175	transmembrane transport
WU17_RS13210	COG1653	transport
WU17_RS13220	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
WU17_RS13235	COG0559	Belongs to the binding-protein-dependent transport system permease family
WU17_RS13255	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
WU17_RS13270	COG0697	spore germination
WU17_RS13280	COG2311	Membrane
WU17_RS13305	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
WU17_RS13315	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
WU17_RS13320	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
WU17_RS13325	COG1760	l-serine dehydratase
WU17_RS13330	COG1283	sodium-dependent phosphate transmembrane transporter activity
WU17_RS13335	COG0412	Dienelactone hydrolase
WU17_RS13350	COG1611	Belongs to the LOG family
WU17_RS13370	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
WU17_RS13375	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
WU17_RS13380	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
WU17_RS13385	COG2251	uridine kinase activity
WU17_RS13385	COG0195	Participates in both transcription termination and antitermination
WU17_RS13390	COG0779	Required for maturation of 30S ribosomal subunits
WU17_RS13395	COG1187	pseudouridine synthase activity
WU17_RS13400	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
WU17_RS13410	COG0583	DNA-binding transcription factor activity
WU17_RS13420	COG0523	cobalamin synthesis protein
WU17_RS13440	COG0625	glutathione transferase activity
WU17_RS13445	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
WU17_RS13450	COG1047	Peptidyl-prolyl cis-trans
WU17_RS13455	COG2003	Belongs to the UPF0758 family
WU17_RS13460	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
WU17_RS13465	COG3483	tryptophan 2,3-dioxygenase activity
WU17_RS13470	COG0254	rRNA binding
WU17_RS13480	COG0534	Mate efflux family protein
WU17_RS13500	COG2304	oxidoreductase activity
WU17_RS13520	COG1028	Short-chain dehydrogenase reductase Sdr
WU17_RS13525	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
WU17_RS13530	COG1562	ergosterol biosynthetic process
WU17_RS13535	COG1562	ergosterol biosynthetic process
WU17_RS13540	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
WU17_RS13540	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
WU17_RS13545	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
WU17_RS13555	COG0842	Transport permease protein
WU17_RS13560	COG1131	(ABC) transporter
WU17_RS13580	COG1477	protein flavinylation
WU17_RS13595	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
WU17_RS13610	COG5564	TIM-barrel signal transduction protein
WU17_RS13615	COG5441	Belongs to the UPF0261 family
WU17_RS13625	COG3468	outer membrane autotransporter barrel domain protein
WU17_RS13630	COG3468	outer membrane autotransporter barrel domain protein
WU17_RS13645	COG0542	response to heat
WU17_RS13650	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
WU17_RS13665	COG0494	nUDIX hydrolase
WU17_RS13670	COG3530	Putative quorum-sensing-regulated virulence factor
WU17_RS13680	COG1595	DNA-templated transcription, initiation
WU17_RS13685	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WU17_RS13720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WU17_RS13725	COG0765	amino acid transport
WU17_RS13730	COG0765	amino acid transport
WU17_RS13760	COG2988	succinylglutamate desuccinylase activity
WU17_RS13785	COG3181	Tripartite tricarboxylate transporter family receptor
WU17_RS13790	COG2084	Dehydrogenase
WU17_RS13805	COG1619	proteins homologs of microcin C7 resistance protein MccF
WU17_RS13820	COG2814	Major facilitator Superfamily
WU17_RS13830	COG0583	DNA-binding transcription factor activity
WU17_RS13870	COG0672	)-iron permease
WU17_RS13885	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
WU17_RS13890	COG1028	Short-chain dehydrogenase reductase Sdr
WU17_RS13895	COG3243	poly(R)-hydroxyalkanoic acid synthase
WU17_RS13905	COG0564	pseudouridine synthase activity
WU17_RS13915	COG1199	ATP-dependent helicase activity
WU17_RS13920	COG2183	response to ionizing radiation
WU17_RS13925	COG0180	Tryptophanyl-tRNA synthetase
WU17_RS13950	COG3181	Tripartite tricarboxylate transporter family receptor
WU17_RS13960	COG0583	DNA-binding transcription factor activity
WU17_RS13965	COG1028	Short-chain dehydrogenase reductase Sdr
WU17_RS13970	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
WU17_RS13975	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WU17_RS13980	COG0508	dehydrogenase complex catalyzes the overall conversion of
WU17_RS13985	COG0567	Dehydrogenase, E1 component
WU17_RS13995	COG1522	sequence-specific DNA binding
WU17_RS14005	COG0281	malic enzyme
WU17_RS14005	COG0280	phosphate acetyltransferase
WU17_RS14010	COG3539	Fimbrial protein
WU17_RS14025	COG0613	PHP domain protein
WU17_RS14035	COG0658	competence protein
WU17_RS14035	COG2333	competence protein COMEC
WU17_RS14065	COG0084	hydrolase, TatD family'
WU17_RS14070	COG1136	(ABC) transporter
WU17_RS14085	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
WU17_RS14095	COG1028	Short-chain dehydrogenase reductase Sdr
WU17_RS14100	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
WU17_RS14115	COG1022	Amp-dependent synthetase and ligase
WU17_RS14150	COG2205	protein histidine kinase activity
WU17_RS14155	COG0745	RESPONSE REGULATOR receiver
WU17_RS14160	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
WU17_RS14170	COG1295	ribonuclease BN
WU17_RS14185	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
WU17_RS14215	COG1534	Rna-binding protein
WU17_RS14220	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
WU17_RS14225	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
WU17_RS14235	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
WU17_RS14245	COG0248	Ppx GppA phosphatase
WU17_RS14270	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
WU17_RS14285	COG2732	(Barnase) inhibitor
WU17_RS14295	COG0280	phosphate acetyltransferase
WU17_RS14295	COG0281	malic enzyme
WU17_RS14305	COG0436	Aminotransferase
WU17_RS14310	COG0741	lytic transglycosylase activity
WU17_RS14315	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
WU17_RS14340	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
WU17_RS14340	COG1648	precorrin-2 dehydrogenase activity
WU17_RS14345	COG3468	outer membrane autotransporter barrel domain protein
WU17_RS14355	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
WU17_RS14360	COG2027	D-alanyl-D-alanine carboxypeptidase
WU17_RS14365	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
WU17_RS14370	COG0343	queuine tRNA-ribosyltransferase activity
WU17_RS14375	COG1862	Preprotein translocase
WU17_RS14380	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WU17_RS14385	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WU17_RS14400	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
WU17_RS14405	COG1702	phosphate starvation-inducible protein PhoH
WU17_RS14410	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
WU17_RS14415	COG4535	Mg2 and Co2 transporter CorC
WU17_RS14425	COG0667	Aldo Keto reductase
WU17_RS14450	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
WU17_RS14455	COG0745	RESPONSE REGULATOR receiver
WU17_RS14460	COG2201	protein-glutamate methylesterase activity
WU17_RS14470	COG0840	transmembrane signaling receptor activity
WU17_RS14485	COG0745	RESPONSE REGULATOR receiver
WU17_RS14520	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
WU17_RS14530	COG0739	heme binding
WU17_RS14540	COG0521	Mo-molybdopterin cofactor biosynthetic process
WU17_RS14550	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
WU17_RS14585	COG0625	glutathione transferase activity
WU17_RS14600	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
WU17_RS14605	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
WU17_RS14610	COG0126	phosphoglycerate kinase activity
WU17_RS14615	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
WU17_RS14620	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
WU17_RS14625	COG1385	rRNA (uridine-N3-)-methyltransferase activity
WU17_RS14635	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
WU17_RS14640	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WU17_RS14645	COG0508	dehydrogenase complex catalyzes the overall conversion of
WU17_RS14650	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
WU17_RS14660	COG4566	intracellular signal transduction
WU17_RS14665	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
WU17_RS14670	COG0339	signal peptide processing
WU17_RS14675	COG1999	signal sequence binding
WU17_RS14695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WU17_RS14705	COG1187	pseudouridine synthase activity
WU17_RS14710	COG3161	chorismate lyase activity
WU17_RS14715	COG2814	Major facilitator Superfamily
WU17_RS14725	COG0667	Aldo Keto reductase
WU17_RS14740	COG0335	large ribosomal subunit rRNA binding
WU17_RS14770	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
WU17_RS14775	COG4208	sulfate ABC transporter
WU17_RS14780	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
WU17_RS14795	COG0450	alkyl hydroperoxide reductase
WU17_RS14800	COG1960	acyl-CoA dehydrogenase activity
WU17_RS14815	COG0123	including yeast histone deacetylase and acetoin utilization protein
WU17_RS14820	COG2951	lytic endotransglycosylase activity
WU17_RS14835	COG1555	photosystem II stabilization
WU17_RS14835	COG1596	polysaccharide export
WU17_RS14840	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WU17_RS14845	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
WU17_RS14850	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
WU17_RS14870	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
WU17_RS14875	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
WU17_RS14880	COG0287	Prephenate dehydrogenase
WU17_RS14890	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
WU17_RS14905	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
WU17_RS14915	COG2814	Major facilitator Superfamily
WU17_RS14940	COG0583	DNA-binding transcription factor activity
WU17_RS14980	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
WU17_RS14995	COG0667	Aldo Keto reductase
WU17_RS15005	COG5265	(ABC) transporter
WU17_RS15050	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
WU17_RS15055	COG0439	Biotin carboxylase
WU17_RS15060	COG2188	Transcriptional regulator
WU17_RS15085	COG0511	ligase activity, forming carbon-carbon bonds
WU17_RS15095	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
WU17_RS15115	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
WU17_RS15135	COG0500	methyltransferase
WU17_RS15140	COG5265	(ABC) transporter
WU17_RS15155	COG0028	Belongs to the TPP enzyme family
WU17_RS15160	COG0440	acetolactate synthase activity
WU17_RS15165	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
WU17_RS15170	COG1183	phosphatidylcholine synthase activity
WU17_RS15185	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
WU17_RS15190	COG1185	polyribonucleotide nucleotidyltransferase activity
WU17_RS15205	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
WU17_RS15225	COG0149	triose-phosphate isomerase activity
WU17_RS15230	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
WU17_RS15240	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
WU17_RS15250	COG3799	methylaspartate ammonia-lyase activity
WU17_RS15285	COG0583	DNA-binding transcription factor activity
WU17_RS15290	COG0626	cystathionine gamma-synthase activity
WU17_RS15295	COG3608	succinylglutamate desuccinylase aspartoacylase
WU17_RS15315	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WU17_RS15335	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
WU17_RS15350	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WU17_RS15355	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WU17_RS15360	COG1733	regulation of RNA biosynthetic process
WU17_RS15370	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
WU17_RS15375	COG0583	DNA-binding transcription factor activity
WU17_RS15380	COG1597	lipid kinase activity
WU17_RS15390	COG0671	phosphoesterase, PA-phosphatase related
WU17_RS15420	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WU17_RS15425	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WU17_RS15430	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WU17_RS15435	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WU17_RS15440	COG0649	NAD binding
WU17_RS15445	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
WU17_RS15455	COG1034	ATP synthesis coupled electron transport
WU17_RS15460	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
WU17_RS15465	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WU17_RS15475	COG0713	ATP synthesis coupled electron transport
WU17_RS15490	COG1007	ATP synthesis coupled electron transport
WU17_RS15500	COG4774	siderophore transport
WU17_RS15505	COG4774	siderophore transport
WU17_RS15520	COG0028	Belongs to the TPP enzyme family
WU17_RS15525	COG3181	Tripartite tricarboxylate transporter family receptor
WU17_RS15530	COG0583	DNA-binding transcription factor activity
WU17_RS15535	COG0560	Phosphoserine phosphatase
WU17_RS15540	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
WU17_RS15545	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
WU17_RS15550	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
WU17_RS15560	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
WU17_RS15565	COG0308	aminopeptidase N
WU17_RS15585	COG0028	Belongs to the TPP enzyme family
WU17_RS15605	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WU17_RS15615	COG0318	PFAM AMP-dependent synthetase and ligase
WU17_RS15625	COG1802	Transcriptional regulator
WU17_RS15635	COG1802	Transcriptional regulator
WU17_RS15645	COG1028	Short-chain dehydrogenase reductase Sdr
WU17_RS15665	COG1126	abc transporter atp-binding protein
WU17_RS15670	COG0765	amino acid transport
WU17_RS15675	COG0765	amino acid transport
WU17_RS15690	COG1538	Outer membrane efflux protein
WU17_RS15695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WU17_RS15700	COG2274	protein secretion by the type I secretion system
WU17_RS15705	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
WU17_RS15715	COG2994	toxin metabolic process
WU17_RS15730	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WU17_RS15735	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
WU17_RS15745	COG0583	DNA-binding transcription factor activity
WU17_RS15755	COG0142	geranyltranstransferase activity
WU17_RS15765	COG0261	This protein binds to 23S rRNA in the presence of protein L20
WU17_RS15770	COG0211	Belongs to the bacterial ribosomal protein bL27 family
WU17_RS15775	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
WU17_RS15780	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
WU17_RS15825	COG3712	iron ion homeostasis
WU17_RS15830	COG4774	siderophore transport
WU17_RS15835	COG2353	YceI-like domain
WU17_RS15850	COG0019	diaminopimelate decarboxylase activity
WU17_RS15870	COG0747	negative chemotaxis
WU17_RS15875	COG0601	transmembrane transport
WU17_RS15880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WU17_RS15890	COG0154	amidase activity
WU17_RS15895	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
WU17_RS15920	COG2154	pterin-4-alpha-carbinolamine dehydratase
WU17_RS15930	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
WU17_RS15940	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
WU17_RS15945	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
WU17_RS15950	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
WU17_RS15955	COG1929	Belongs to the glycerate kinase type-1 family
WU17_RS15960	COG0469	pyruvate kinase activity
WU17_RS15965	COG0700	Nucleoside recognition
WU17_RS16000	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
WU17_RS16005	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WU17_RS16020	COG0823	Involved in the tonB-independent uptake of proteins
WU17_RS16030	COG0848	biopolymer transport protein
WU17_RS16035	COG0811	peptide transport
WU17_RS16040	COG0824	Thioesterase
WU17_RS16045	COG0442	prolyl-tRNA aminoacylation
WU17_RS16050	COG0494	nUDIX hydrolase
WU17_RS16065	COG2135	peptidase activity
WU17_RS16135	COG1196	nuclear chromosome segregation
WU17_RS16280	COG1464	Belongs to the NlpA lipoprotein family
WU17_RS16310	COG4211	Belongs to the binding-protein-dependent transport system permease family
WU17_RS16320	COG0154	amidase activity
WU17_RS16325	COG0288	reversible hydration of carbon dioxide
WU17_RS16340	COG0514	ATP-dependent DNA helicase (RecQ)
WU17_RS16345	COG2255	four-way junction helicase activity
WU17_RS16360	COG0632	four-way junction helicase activity
WU17_RS16365	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
WU17_RS16385	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WU17_RS16395	COG0006	proline dipeptidase activity
WU17_RS16420	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WU17_RS16435	COG4783	chaperone-mediated protein folding
WU17_RS16440	COG0429	hydrolase of the alpha beta-hydrolase fold
WU17_RS16470	COG0513	Belongs to the DEAD box helicase family
WU17_RS16490	COG1058	Belongs to the CinA family
WU17_RS16490	COG1546	Belongs to the CinA family
WU17_RS16495	COG1414	Transcriptional regulator
WU17_RS16515	COG0167	dihydroorotate dehydrogenase activity
WU17_RS16520	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
WU17_RS16525	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
WU17_RS16535	COG0583	DNA-binding transcription factor activity
WU17_RS16595	COG0281	malic enzyme
WU17_RS16595	COG0280	phosphate acetyltransferase
WU17_RS16615	COG0601	transmembrane transport
WU17_RS16620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WU17_RS16625	COG4172	Belongs to the ABC transporter superfamily
WU17_RS16655	COG0640	Transcriptional regulator
WU17_RS16670	COG3135	benzoate transporter
WU17_RS16675	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
WU17_RS16680	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
WU17_RS16685	COG0742	ribosomal rna small subunit methyltransferase
WU17_RS16700	COG3639	organic phosphonate transmembrane transporter activity
WU17_RS16705	COG3639	organic phosphonate transmembrane transporter activity
WU17_RS16710	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
WU17_RS16745	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
WU17_RS16750	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
WU17_RS16760	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
WU17_RS16765	COG1058	Belongs to the CinA family
WU17_RS16765	COG1546	Belongs to the CinA family
WU17_RS16770	COG0284	orotidine-5'-phosphate decarboxylase activity
WU17_RS16775	COG1252	NADH dehydrogenase
WU17_RS16790	COG3468	outer membrane autotransporter barrel domain protein
WU17_RS16795	COG0459	protein refolding
WU17_RS16800	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
WU17_RS16820	COG1053	succinate dehydrogenase
WU17_RS16830	COG0583	DNA-binding transcription factor activity
WU17_RS16835	COG1053	succinate dehydrogenase
WU17_RS16855	COG3706	GGDEF domain
WU17_RS16890	COG1262	PFAM Formylglycine-generating sulfatase enzyme
WU17_RS16895	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
WU17_RS16905	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WU17_RS16915	COG0069	glutamate synthase activity
WU17_RS16920	COG2391	methyltransferase activity
WU17_RS16925	COG0679	Auxin Efflux Carrier
WU17_RS16950	COG0557	exoribonuclease II activity
WU17_RS16955	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
WU17_RS16965	COG3128	pkhd-type hydroxylase
WU17_RS16970	COG0776	regulation of translation
WU17_RS17000	COG0642	Histidine kinase
WU17_RS17005	COG3158	transport of potassium into the cell
WU17_RS17010	COG0137	argininosuccinate synthase activity
WU17_RS17015	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
WU17_RS17020	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
WU17_RS17030	COG0583	DNA-binding transcription factor activity
WU17_RS17040	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
WU17_RS17060	COG2186	Transcriptional regulator
WU17_RS17070	COG2223	nitrite transmembrane transporter activity
WU17_RS17080	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WU17_RS17085	COG0450	alkyl hydroperoxide reductase
WU17_RS17105	COG1214	PFAM Peptidase M22, glycoprotease
WU17_RS17110	COG1573	uracil-dna glycosylase
WU17_RS17115	COG0477	Major facilitator Superfamily
WU17_RS17120	COG1196	nuclear chromosome segregation
WU17_RS17130	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
WU17_RS17135	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
WU17_RS17150	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
WU17_RS17155	COG1122	ATPase activity
WU17_RS17160	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
WU17_RS17165	COG1268	BioY protein
WU17_RS17185	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
WU17_RS17220	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
WU17_RS17225	COG2878	Part of a membrane complex involved in electron transport
WU17_RS17240	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
WU17_RS17245	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
WU17_RS17250	COG0251	oxidation-reduction process
WU17_RS17260	COG3228	Belongs to the MtfA family
WU17_RS17265	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
WU17_RS17275	COG0133	tryptophan synthase activity
WU17_RS17280	COG0159	tryptophan synthase activity
WU17_RS17285	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
WU17_RS17290	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
WU17_RS17305	COG1530	ribonuclease E activity
WU17_RS17315	COG0546	phosphoglycolate phosphatase activity
WU17_RS17320	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
WU17_RS17325	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
WU17_RS17335	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU17_RS17340	COG0583	DNA-binding transcription factor activity
WU17_RS17350	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU17_RS17370	COG0251	oxidation-reduction process
WU17_RS17375	COG1017	nitric oxide dioxygenase activity
WU17_RS17375	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WU17_RS17380	COG2031	fatty acid transporter
WU17_RS17385	COG1012	belongs to the aldehyde dehydrogenase family
WU17_RS17390	COG1802	Transcriptional regulator
WU17_RS17400	COG1278	Cold shock
WU17_RS17405	COG0583	DNA-binding transcription factor activity
WU17_RS17420	COG0183	Belongs to the thiolase family
WU17_RS17430	COG1960	acyl-CoA dehydrogenase activity
WU17_RS17435	COG0583	DNA-binding transcription factor activity
WU17_RS17440	COG3181	Tripartite tricarboxylate transporter family receptor
WU17_RS17445	COG1024	Enoyl-CoA hydratase
WU17_RS17450	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU17_RS17455	COG1253	flavin adenine dinucleotide binding
WU17_RS17460	COG1285	pathogenesis
WU17_RS17470	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WU17_RS17485	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
WU17_RS17495	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WU17_RS17505	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU17_RS17510	COG3181	Tripartite tricarboxylate transporter family receptor
WU17_RS17515	COG1960	acyl-CoA dehydrogenase activity
WU17_RS17535	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
WU17_RS17540	COG1024	Enoyl-CoA hydratase
WU17_RS17545	COG1960	acyl-CoA dehydrogenase activity
WU17_RS17565	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
WU17_RS17570	COG0022	dehydrogenase e1 component
WU17_RS17575	COG1024	Enoyl-CoA hydratase
WU17_RS17580	COG0508	dehydrogenase complex catalyzes the overall conversion of
WU17_RS17600	COG0683	leucine binding
WU17_RS17605	COG0559	Belongs to the binding-protein-dependent transport system permease family
WU17_RS17610	COG0411	ABC transporter
WU17_RS17620	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WU17_RS17635	COG3181	Tripartite tricarboxylate transporter family receptor
WU17_RS17660	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
WU17_RS17665	COG0793	Belongs to the peptidase S41A family
WU17_RS17670	COG4942	peptidase
WU17_RS17675	COG0588	phosphoglycerate mutase activity
WU17_RS17680	COG1054	Belongs to the UPF0176 family
WU17_RS17685	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
WU17_RS17690	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
WU17_RS17695	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
WU17_RS17700	COG3181	Tripartite tricarboxylate transporter family receptor
WU17_RS17715	COG2226	methyltransferase
WU17_RS17720	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
WU17_RS17735	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WU17_RS17740	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
WU17_RS17765	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
WU17_RS17790	COG1335	isochorismatase
WU17_RS17795	COG2309	aminopeptidase activity
WU17_RS17800	COG0596	Alpha beta hydrolase
WU17_RS17805	COG3473	Maleate cis-trans isomerase
WU17_RS17815	COG2068	MobA-Related Protein
WU17_RS17840	COG2204	response regulator
WU17_RS17845	COG5000	phosphorelay sensor kinase activity
WU17_RS17855	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
WU17_RS17855	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
WU17_RS17865	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
WU17_RS17890	COG0583	DNA-binding transcription factor activity
WU17_RS17905	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
WU17_RS17910	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WU17_RS17915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WU17_RS17930	COG0758	DNA mediated transformation
WU17_RS17935	COG1522	sequence-specific DNA binding
WU17_RS17945	COG0242	peptide deformylase activity
WU17_RS17960	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
WU17_RS17970	COG0546	phosphoglycolate phosphatase activity
WU17_RS17990	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
WU17_RS17995	COG1942	4-Oxalocrotonate Tautomerase
WU17_RS18000	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WU17_RS18025	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
WU17_RS18045	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WU17_RS18050	COG1024	Enoyl-CoA hydratase
WU17_RS18055	COG1414	Transcriptional regulator
WU17_RS18060	COG0318	PFAM AMP-dependent synthetase and ligase
WU17_RS18065	COG3181	Tripartite tricarboxylate transporter family receptor
WU17_RS18095	COG0583	DNA-binding transcription factor activity
WU17_RS18110	COG3422	double-strand break repair
WU17_RS18115	COG0330	HflC and HflK could
WU17_RS18125	COG0251	oxidation-reduction process
WU17_RS18170	COG3723	Recombinational DNA repair protein, rece pathway
WU17_RS18205	COG0582	viral genome integration into host DNA
WU17_RS18230	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
WU17_RS18240	COG0706	membrane insertase activity
WU17_RS18245	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
WU17_RS18250	COG0594	ribonuclease P activity
WU17_RS18255	COG0230	Belongs to the bacterial ribosomal protein bL34 family
WU17_RS18260	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
WU17_RS18275	COG1414	Transcriptional regulator
WU17_RS18280	COG0154	amidase activity
WU17_RS18295	COG1304	FMN binding
WU17_RS18315	COG1960	acyl-CoA dehydrogenase activity
WU17_RS18335	COG1960	acyl-CoA dehydrogenase activity
WU17_RS18350	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
WU17_RS18365	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
WU17_RS18370	COG3181	Tripartite tricarboxylate transporter family receptor
WU17_RS18380	COG2358	TRAP transporter, solute receptor (TAXI family
WU17_RS18390	COG1629	transport
WU17_RS18395	COG2922	Belongs to the Smg family
WU17_RS18420	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
WU17_RS18425	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WU17_RS18430	COG1028	Short-chain dehydrogenase reductase Sdr
WU17_RS18435	COG1012	belongs to the aldehyde dehydrogenase family
WU17_RS18445	COG0028	Belongs to the TPP enzyme family
WU17_RS18450	COG1522	sequence-specific DNA binding
WU17_RS18455	COG3781	membrane
WU17_RS18465	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
WU17_RS18485	COG4206	TonB-dependent receptor
WU17_RS18490	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
WU17_RS18495	COG2022	thiamine diphosphate biosynthetic process
WU17_RS18500	COG0351	phosphomethylpyrimidine kinase
WU17_RS18505	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
WU17_RS18520	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
WU17_RS18530	COG0628	permease
WU17_RS18540	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
WU17_RS18550	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
WU17_RS18555	COG0049	tRNA binding
WU17_RS18560	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
WU17_RS18565	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
WU17_RS18570	COG0051	transcription antitermination factor activity, RNA binding
WU17_RS18575	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
WU17_RS18580	COG0088	Forms part of the polypeptide exit tunnel
WU17_RS18585	COG0089	rRNA binding
WU17_RS18590	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
WU17_RS18595	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
WU17_RS18600	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
WU17_RS18605	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
WU17_RS18610	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
WU17_RS18615	COG0255	Belongs to the universal ribosomal protein uL29 family
WU17_RS18620	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
WU17_RS18640	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
WU17_RS18645	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
WU17_RS18650	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
WU17_RS18655	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
WU17_RS18660	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
WU17_RS18665	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
WU17_RS18670	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
WU17_RS18675	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
WU17_RS18680	COG1841	ribosomal large subunit assembly
WU17_RS18685	COG0200	Binds to the 23S rRNA
WU17_RS18690	COG0201	protein transport
WU17_RS18695	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
WU17_RS18700	COG0257	Belongs to the bacterial ribosomal protein bL36 family
WU17_RS18705	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
WU17_RS18710	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
WU17_RS18715	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
WU17_RS18720	COG0202	RNA polymerase activity
WU17_RS18725	COG0203	ribosomal protein L17
WU17_RS18730	COG0537	adenosine 5'-monophosphoramidase activity
WU17_RS18735	COG1324	tolerance protein
WU17_RS18740	COG4232	protein-disulfide reductase activity
WU17_RS18755	COG0218	Necessary for normal cell division and for the maintenance of normal septation
WU17_RS18765	COG1333	cytochrome c biogenesis protein
WU17_RS18770	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
WU17_RS18785	COG1965	Belongs to the frataxin family
WU17_RS18795	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
WU17_RS18800	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
WU17_RS18805	COG0232	Belongs to the dGTPase family. Type 2 subfamily
WU17_RS18820	COG2814	Major facilitator Superfamily
WU17_RS18825	COG0629	single-stranded DNA binding
WU17_RS18865	COG0402	S-adenosylhomocysteine deaminase activity
WU17_RS18875	COG0438	transferase activity, transferring glycosyl groups
WU17_RS18895	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WU17_RS18920	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
WU17_RS18925	COG2186	Transcriptional regulator
WU17_RS18945	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WU17_RS18950	COG1956	GAF domain-containing protein
WU17_RS18955	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WU17_RS18970	COG1652	LysM domain
WU17_RS18985	COG0220	tRNA (guanine-N7-)-methyltransferase activity
WU17_RS19000	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
WU17_RS19030	COG3181	Tripartite tricarboxylate transporter family receptor
WU17_RS19045	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WU17_RS19060	COG1024	Enoyl-CoA hydratase
WU17_RS19075	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU17_RS19080	COG1309	transcriptional regulator
WU17_RS19085	COG2816	NAD+ diphosphatase activity
WU17_RS19090	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WU17_RS19175	COG2814	Major facilitator Superfamily
WU17_RS19180	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
WU17_RS19200	COG1999	signal sequence binding
WU17_RS19205	COG0109	protoheme IX farnesyltransferase activity
WU17_RS19245	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
WU17_RS19265	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
WU17_RS19270	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
WU17_RS19280	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
WU17_RS19285	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
WU17_RS19295	COG0069	glutamate synthase activity
WU17_RS19295	COG0070	glutamate synthase
WU17_RS19295	COG0067	glutamate synthase
WU17_RS19305	COG3047	cAMP biosynthetic process
WU17_RS19315	COG1127	ABC transporter
WU17_RS19320	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
WU17_RS19325	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
WU17_RS19330	COG2853	Lipoprotein
WU17_RS19340	COG1131	(ABC) transporter
WU17_RS19345	COG0842	Transport permease protein
WU17_RS19355	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
WU17_RS19360	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
WU17_RS19365	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
WU17_RS19370	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
WU17_RS19375	COG0131	Imidazoleglycerol-phosphate dehydratase
WU17_RS19380	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
WU17_RS19385	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
WU17_RS19390	COG0107	imidazoleglycerol-phosphate synthase activity
WU17_RS19395	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
WU17_RS19400	COG0140	phosphoribosyl-ATP diphosphatase activity
WU17_RS19405	COG0537	adenosine 5'-monophosphoramidase activity
WU17_RS19410	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
WU17_RS19415	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
WU17_RS19430	COG3181	Tripartite tricarboxylate transporter family receptor
WU17_RS19465	COG3702	type iv secretory pathway
WU17_RS19470	COG3451	type IV secretory pathway VirB4
WU17_RS19485	COG3736	Type IV secretory pathway, component VirB8
WU17_RS19490	COG3504	Conjugal transfer protein
WU17_RS19495	COG2948	multi-organism process
WU17_RS19500	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
WU17_RS19510	COG0697	spore germination
WU17_RS19530	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
WU17_RS19535	COG0747	negative chemotaxis
WU17_RS19540	COG0601	transmembrane transport
WU17_RS19545	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WU17_RS19550	COG0444	Belongs to the ABC transporter superfamily
WU17_RS19560	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
WU17_RS19570	COG0494	nUDIX hydrolase
WU17_RS19610	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
WU17_RS19615	COG0237	dephospho-CoA kinase activity
WU17_RS19620	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
WU17_RS19635	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
WU17_RS19640	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
WU17_RS19650	COG0477	Major facilitator Superfamily
WU17_RS19655	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
WU17_RS19670	COG1126	abc transporter atp-binding protein
WU17_RS19675	COG0765	amino acid transport
WU17_RS19680	COG4597	amino acid ABC transporter
WU17_RS19685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WU17_RS19690	COG2884	Cell division ATP-binding protein ftsE
WU17_RS19695	COG2177	Part of the ABC transporter FtsEX involved in
WU17_RS19700	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
WU17_RS19710	COG1194	a g-specific adenine glycosylase
WU17_RS19720	COG2226	methyltransferase
WU17_RS19730	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU17_RS19735	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU17_RS19750	COG1024	Enoyl-CoA hydratase
WU17_RS19770	COG1024	Enoyl-CoA hydratase
WU17_RS19775	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU17_RS19780	COG3181	Tripartite tricarboxylate transporter family receptor
WU17_RS19790	COG0753	catalase activity
WU17_RS19795	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WU17_RS19800	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
WU17_RS19810	COG2175	clavaminate synthase activity
WU17_RS19815	COG1473	amidohydrolase
WU17_RS19820	COG4608	Belongs to the ABC transporter superfamily
WU17_RS19825	COG0444	Belongs to the ABC transporter superfamily
WU17_RS19840	COG0747	negative chemotaxis
WU17_RS19845	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
WU17_RS19880	COG0436	Aminotransferase
WU17_RS19885	COG1278	Cold shock