locus-tag	class	description
RD09_RS00005	COG0445	tRNA wobble uridine modification
RD09_RS00010	COG0357	Ribosomal RNA small subunit methyltransferase G
RD09_RS00015	COG1192	Involved in chromosome partitioning
RD09_RS00025	COG1475	DNA binding
RD09_RS00030	COG0252	asparaginase activity
RD09_RS00055	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
RD09_RS00065	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
RD09_RS00075	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
RD09_RS00080	COG0081	regulation of translation
RD09_RS00085	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
RD09_RS00090	COG0222	ribosome binding
RD09_RS00095	COG0085	RNA polymerase activity
RD09_RS00100	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
RD09_RS00140	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD09_RS00165	COG1024	Enoyl-CoA hydratase
RD09_RS00185	COG0752	glycyl-tRNA synthetase alpha subunit
RD09_RS00190	COG0751	glycine-tRNA ligase activity
RD09_RS00195	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
RD09_RS00200	COG0204	Acyl-transferase
RD09_RS00215	COG0242	peptide deformylase activity
RD09_RS00250	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
RD09_RS00255	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
RD09_RS00260	COG2813	Specifically methylates the guanine in position
RD09_RS00260	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
RD09_RS00270	COG2223	nitrite transmembrane transporter activity
RD09_RS00280	COG1794	racemase activity, acting on amino acids and derivatives
RD09_RS00285	COG1126	abc transporter atp-binding protein
RD09_RS00290	COG0765	amino acid transport
RD09_RS00295	COG0765	amino acid transport
RD09_RS00300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RD09_RS00360	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
RD09_RS00390	COG0326	Molecular chaperone. Has ATPase activity
RD09_RS00395	COG0625	glutathione transferase activity
RD09_RS00410	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
RD09_RS00415	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
RD09_RS00445	COG0438	transferase activity, transferring glycosyl groups
RD09_RS00450	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
RD09_RS00455	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
RD09_RS00485	COG0859	PFAM glycosyl transferase family 9
RD09_RS00500	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
RD09_RS00510	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
RD09_RS00515	COG1127	ABC transporter
RD09_RS00540	COG1686	Belongs to the peptidase S11 family
RD09_RS00550	COG2921	Belongs to the UPF0250 family
RD09_RS00555	COG0321	lipoyl(octanoyl) transferase activity
RD09_RS00560	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
RD09_RS00595	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
RD09_RS00605	COG0018	arginyl-trna synthetase
RD09_RS00625	COG0395	ABC-type sugar transport system, permease component
RD09_RS00630	COG1175	transmembrane transport
RD09_RS00635	COG1653	transport
RD09_RS00640	COG3842	ATPase activity
RD09_RS00645	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
RD09_RS00715	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
RD09_RS00720	COG2816	NAD+ diphosphatase activity
RD09_RS00725	COG1309	transcriptional regulator
RD09_RS00730	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD09_RS00745	COG1024	Enoyl-CoA hydratase
RD09_RS00760	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RD09_RS00775	COG3181	Tripartite tricarboxylate transporter family receptor
RD09_RS00800	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RD09_RS00815	COG0220	tRNA (guanine-N7-)-methyltransferase activity
RD09_RS00830	COG1652	LysM domain
RD09_RS00840	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RD09_RS00845	COG1956	GAF domain-containing protein
RD09_RS00850	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RD09_RS00870	COG2186	Transcriptional regulator
RD09_RS00875	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
RD09_RS00900	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RD09_RS00920	COG0438	transferase activity, transferring glycosyl groups
RD09_RS00930	COG0402	S-adenosylhomocysteine deaminase activity
RD09_RS00970	COG0629	single-stranded DNA binding
RD09_RS00975	COG2814	Major facilitator Superfamily
RD09_RS00990	COG0232	Belongs to the dGTPase family. Type 2 subfamily
RD09_RS00995	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
RD09_RS01000	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
RD09_RS01010	COG1965	Belongs to the frataxin family
RD09_RS01020	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
RD09_RS01025	COG1333	cytochrome c biogenesis protein
RD09_RS01035	COG0218	Necessary for normal cell division and for the maintenance of normal septation
RD09_RS01050	COG4232	protein-disulfide reductase activity
RD09_RS01055	COG1324	tolerance protein
RD09_RS01060	COG0537	adenosine 5'-monophosphoramidase activity
RD09_RS01065	COG0203	ribosomal protein L17
RD09_RS01070	COG0202	RNA polymerase activity
RD09_RS01075	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
RD09_RS01080	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
RD09_RS01085	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
RD09_RS01090	COG0257	Belongs to the bacterial ribosomal protein bL36 family
RD09_RS01095	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
RD09_RS01100	COG0201	protein transport
RD09_RS01105	COG0200	Binds to the 23S rRNA
RD09_RS01110	COG1841	ribosomal large subunit assembly
RD09_RS01115	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
RD09_RS01120	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
RD09_RS01125	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
RD09_RS01130	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
RD09_RS01135	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
RD09_RS01140	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
RD09_RS01145	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
RD09_RS01150	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
RD09_RS01170	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
RD09_RS01175	COG0255	Belongs to the universal ribosomal protein uL29 family
RD09_RS01180	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
RD09_RS01185	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
RD09_RS01190	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
RD09_RS01195	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
RD09_RS01200	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
RD09_RS01205	COG0089	rRNA binding
RD09_RS01210	COG0088	Forms part of the polypeptide exit tunnel
RD09_RS01215	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
RD09_RS01220	COG0051	transcription antitermination factor activity, RNA binding
RD09_RS01225	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
RD09_RS01230	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
RD09_RS01235	COG0049	tRNA binding
RD09_RS01240	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
RD09_RS01250	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
RD09_RS01260	COG0628	permease
RD09_RS01270	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
RD09_RS01285	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
RD09_RS01290	COG0351	phosphomethylpyrimidine kinase
RD09_RS01295	COG2022	thiamine diphosphate biosynthetic process
RD09_RS01300	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RD09_RS01305	COG4206	TonB-dependent receptor
RD09_RS01325	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
RD09_RS01335	COG3781	membrane
RD09_RS01340	COG1522	sequence-specific DNA binding
RD09_RS01345	COG0028	Belongs to the TPP enzyme family
RD09_RS01355	COG1012	belongs to the aldehyde dehydrogenase family
RD09_RS01360	COG1028	Short-chain dehydrogenase reductase Sdr
RD09_RS01365	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RD09_RS01370	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
RD09_RS01395	COG2922	Belongs to the Smg family
RD09_RS01400	COG1629	transport
RD09_RS01410	COG2358	TRAP transporter, solute receptor (TAXI family
RD09_RS01420	COG3181	Tripartite tricarboxylate transporter family receptor
RD09_RS01425	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
RD09_RS01440	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
RD09_RS01445	COG0183	Belongs to the thiolase family
RD09_RS01455	COG1960	acyl-CoA dehydrogenase activity
RD09_RS01475	COG1960	acyl-CoA dehydrogenase activity
RD09_RS01495	COG1304	FMN binding
RD09_RS01510	COG0154	amidase activity
RD09_RS01515	COG1414	Transcriptional regulator
RD09_RS01530	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
RD09_RS01535	COG0230	Belongs to the bacterial ribosomal protein bL34 family
RD09_RS01540	COG0594	ribonuclease P activity
RD09_RS01545	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
RD09_RS01550	COG0706	membrane insertase activity
RD09_RS01560	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
RD09_RS01585	COG0582	viral genome integration into host DNA
RD09_RS01620	COG3723	Recombinational DNA repair protein, rece pathway
RD09_RS01665	COG0251	oxidation-reduction process
RD09_RS01675	COG0330	HflC and HflK could
RD09_RS01680	COG3422	double-strand break repair
RD09_RS01695	COG0583	DNA-binding transcription factor activity
RD09_RS01725	COG3181	Tripartite tricarboxylate transporter family receptor
RD09_RS01730	COG0318	PFAM AMP-dependent synthetase and ligase
RD09_RS01735	COG1414	Transcriptional regulator
RD09_RS01740	COG1024	Enoyl-CoA hydratase
RD09_RS01745	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RD09_RS01765	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
RD09_RS01785	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RD09_RS01790	COG1942	4-Oxalocrotonate Tautomerase
RD09_RS01795	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
RD09_RS01815	COG0546	phosphoglycolate phosphatase activity
RD09_RS01825	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
RD09_RS01835	COG0242	peptide deformylase activity
RD09_RS01845	COG1522	sequence-specific DNA binding
RD09_RS01850	COG0758	DNA mediated transformation
RD09_RS01865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RD09_RS01870	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RD09_RS01875	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
RD09_RS01890	COG0583	DNA-binding transcription factor activity
RD09_RS01915	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
RD09_RS01925	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
RD09_RS01925	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
RD09_RS01935	COG5000	phosphorelay sensor kinase activity
RD09_RS01940	COG2204	response regulator
RD09_RS01965	COG2068	MobA-Related Protein
RD09_RS01975	COG3473	Maleate cis-trans isomerase
RD09_RS01980	COG0596	Alpha beta hydrolase
RD09_RS01985	COG2309	aminopeptidase activity
RD09_RS01990	COG1335	isochorismatase
RD09_RS02015	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
RD09_RS02040	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
RD09_RS02045	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RD09_RS02060	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
RD09_RS02065	COG2226	methyltransferase
RD09_RS02080	COG3181	Tripartite tricarboxylate transporter family receptor
RD09_RS02085	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
RD09_RS02090	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
RD09_RS02095	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
RD09_RS02100	COG1054	Belongs to the UPF0176 family
RD09_RS02105	COG0588	phosphoglycerate mutase activity
RD09_RS02110	COG4942	peptidase
RD09_RS02115	COG0793	Belongs to the peptidase S41A family
RD09_RS02120	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
RD09_RS02145	COG3181	Tripartite tricarboxylate transporter family receptor
RD09_RS02160	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RD09_RS02170	COG0411	ABC transporter
RD09_RS02175	COG0559	Belongs to the binding-protein-dependent transport system permease family
RD09_RS02180	COG0683	leucine binding
RD09_RS02200	COG0508	dehydrogenase complex catalyzes the overall conversion of
RD09_RS02205	COG1024	Enoyl-CoA hydratase
RD09_RS02210	COG0022	dehydrogenase e1 component
RD09_RS02215	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
RD09_RS02235	COG1960	acyl-CoA dehydrogenase activity
RD09_RS02240	COG1024	Enoyl-CoA hydratase
RD09_RS02245	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
RD09_RS02265	COG1960	acyl-CoA dehydrogenase activity
RD09_RS02270	COG3181	Tripartite tricarboxylate transporter family receptor
RD09_RS02275	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD09_RS02285	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RD09_RS02305	COG3181	Tripartite tricarboxylate transporter family receptor
RD09_RS02315	COG0277	FAD linked oxidase domain protein
RD09_RS02320	COG1960	acyl-CoA dehydrogenase activity
RD09_RS02325	COG1960	acyl-CoA dehydrogenase activity
RD09_RS02335	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RD09_RS02355	COG0604	alcohol dehydrogenase
RD09_RS02370	COG1024	Enoyl-CoA hydratase
RD09_RS02390	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
RD09_RS02395	COG1522	sequence-specific DNA binding
RD09_RS02400	COG0183	Belongs to the thiolase family
RD09_RS02410	COG1960	acyl-CoA dehydrogenase activity
RD09_RS02455	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
RD09_RS02460	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
RD09_RS02465	COG2890	protein-(glutamine-N5) methyltransferase activity
RD09_RS02470	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
RD09_RS02480	COG3181	Tripartite tricarboxylate transporter family receptor
RD09_RS02520	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
RD09_RS02525	COG1660	Displays ATPase and GTPase activities
RD09_RS02535	COG2010	Cytochrome c
RD09_RS02535	COG1529	Aldehyde oxidase and xanthine dehydrogenase
RD09_RS02540	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
RD09_RS02550	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
RD09_RS02555	COG1137	ATPase activity
RD09_RS02570	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
RD09_RS02580	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
RD09_RS02615	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
RD09_RS02620	COG3568	Endonuclease Exonuclease Phosphatase
RD09_RS02625	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RD09_RS02655	COG0154	amidase activity
RD09_RS02665	COG1414	Transcriptional regulator
RD09_RS02680	COG1250	3-hydroxyacyl-CoA dehydrogenase
RD09_RS02680	COG1024	Enoyl-CoA hydratase
RD09_RS02690	COG2132	Multicopper oxidase
RD09_RS02720	COG1250	3-hydroxyacyl-CoA dehydrogenase
RD09_RS02745	COG1024	Enoyl-CoA hydratase
RD09_RS02750	COG1024	Enoyl-CoA hydratase
RD09_RS02755	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
RD09_RS02775	COG0601	transmembrane transport
RD09_RS02780	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RD09_RS02785	COG4608	Belongs to the ABC transporter superfamily
RD09_RS02795	COG2195	Cleaves the N-terminal amino acid of tripeptides
RD09_RS02805	COG0210	DNA helicase
RD09_RS02810	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
RD09_RS02815	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
RD09_RS02825	COG0355	proton-transporting ATP synthase activity, rotational mechanism
RD09_RS02830	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
RD09_RS02835	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
RD09_RS02840	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
RD09_RS02845	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
RD09_RS02850	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
RD09_RS02860	COG0356	it plays a direct role in the translocation of protons across the membrane
RD09_RS02885	COG1024	Enoyl-CoA hydratase
RD09_RS02890	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RD09_RS02895	COG3634	alkyl hydroperoxide reductase activity
RD09_RS02905	COG0037	tRNA processing
RD09_RS02915	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RD09_RS02920	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
RD09_RS02925	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RD09_RS02930	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
RD09_RS02935	COG2967	ApaG domain
RD09_RS02940	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
RD09_RS02945	COG0546	phosphoglycolate phosphatase activity
RD09_RS02955	COG0512	Glutamine amidotransferase of anthranilate synthase
RD09_RS02960	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
RD09_RS02965	COG0134	indole-3-glycerol-phosphate synthase activity
RD09_RS02990	COG1960	acyl-CoA dehydrogenase activity
RD09_RS02995	COG0583	DNA-binding transcription factor activity
RD09_RS03010	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RD09_RS03015	COG0259	pyridoxamine-phosphate oxidase activity
RD09_RS03025	COG2814	Major facilitator Superfamily
RD09_RS03030	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
RD09_RS03035	COG2188	Transcriptional regulator
RD09_RS03040	COG0318	PFAM AMP-dependent synthetase and ligase
RD09_RS03060	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
RD09_RS03070	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
RD09_RS03085	COG1215	transferase activity, transferring glycosyl groups
RD09_RS03095	COG0601	transmembrane transport
RD09_RS03105	COG0488	(ABC) transporter
RD09_RS03125	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
RD09_RS03130	COG2894	cell division
RD09_RS03135	COG0850	regulation of cytokinetic process
RD09_RS03140	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
RD09_RS03145	COG1271	oxidase subunit
RD09_RS03180	COG2979	Protein of unknown function (DUF533)
RD09_RS03200	COG1388	LysM domain
RD09_RS03200	COG0741	lytic transglycosylase activity
RD09_RS03205	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RD09_RS03210	COG2226	methyltransferase
RD09_RS03215	COG0328	RNA-DNA hybrid ribonuclease activity
RD09_RS03260	COG2030	dehydratase
RD09_RS03265	COG0183	Belongs to the thiolase family
RD09_RS03310	COG1960	acyl-CoA dehydrogenase activity
RD09_RS03325	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD09_RS03330	COG1028	Short-chain dehydrogenase reductase Sdr
RD09_RS03345	COG2718	Belongs to the UPF0229 family
RD09_RS03350	COG2719	SpoVR family
RD09_RS03375	COG2188	Transcriptional regulator
RD09_RS03390	COG0633	Ferredoxin
RD09_RS03400	COG0829	nickel cation binding
RD09_RS03405	COG0831	urea catabolic process
RD09_RS03415	COG0832	Belongs to the urease beta subunit family
RD09_RS03420	COG0804	urea catabolic process
RD09_RS03430	COG0830	nickel cation binding
RD09_RS03435	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
RD09_RS03455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RD09_RS03460	COG0601	transmembrane transport
RD09_RS03465	COG0747	negative chemotaxis
RD09_RS03475	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
RD09_RS03480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RD09_RS03490	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
RD09_RS03500	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
RD09_RS03505	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
RD09_RS03510	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
RD09_RS03525	COG0438	transferase activity, transferring glycosyl groups
RD09_RS03540	COG0438	transferase activity, transferring glycosyl groups
RD09_RS03545	COG0438	transferase activity, transferring glycosyl groups
RD09_RS03550	COG0166	Belongs to the GPI family
RD09_RS03565	COG0277	FAD linked oxidase domain protein
RD09_RS03570	COG0745	RESPONSE REGULATOR receiver
RD09_RS03575	COG0642	Histidine kinase
RD09_RS03580	COG1368	sulfuric ester hydrolase activity
RD09_RS03590	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
RD09_RS03615	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
RD09_RS03625	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
RD09_RS03630	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
RD09_RS03640	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
RD09_RS03645	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
RD09_RS03650	COG0193	aminoacyl-tRNA hydrolase activity
RD09_RS03660	COG0012	GTP binding
RD09_RS03665	COG0582	viral genome integration into host DNA
RD09_RS03685	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
RD09_RS03735	COG0745	RESPONSE REGULATOR receiver
RD09_RS03750	COG1309	transcriptional regulator
RD09_RS03775	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RD09_RS03785	COG0405	Gamma-glutamyltransferase
RD09_RS03800	COG1280	lysine exporter protein (LysE YggA)
RD09_RS03860	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
RD09_RS03865	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RD09_RS03875	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
RD09_RS03880	COG0513	Belongs to the DEAD box helicase family
RD09_RS03890	COG0617	tRNA 3'-terminal CCA addition
RD09_RS03905	COG0477	Major facilitator Superfamily
RD09_RS03915	COG0583	DNA-binding transcription factor activity
RD09_RS03930	COG1950	PFAM Membrane protein of
RD09_RS03935	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
RD09_RS03950	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
RD09_RS03960	COG1560	Kdo2-lipid A biosynthetic process
RD09_RS03965	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
RD09_RS03975	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
RD09_RS03985	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
RD09_RS03995	COG0803	Belongs to the bacterial solute-binding protein 9 family
RD09_RS04015	COG0735	belongs to the Fur family
RD09_RS04020	COG0523	cobalamin synthesis protein
RD09_RS04030	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
RD09_RS04035	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
RD09_RS04045	COG2096	Adenosyltransferase
RD09_RS04060	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
RD09_RS04065	COG2084	Dehydrogenase
RD09_RS04120	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
RD09_RS04125	COG0129	dihydroxy-acid dehydratase activity
RD09_RS04130	COG4654	Cytochrome c, class I
RD09_RS04135	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
RD09_RS04185	COG1473	amidohydrolase
RD09_RS04190	COG0418	dihydroorotase activity
RD09_RS04195	COG0488	(ABC) transporter
RD09_RS04205	COG2001	Belongs to the MraZ family
RD09_RS04210	COG0275	rRNA processing
RD09_RS04215	COG3116	cell division
RD09_RS04225	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
RD09_RS04230	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
RD09_RS04235	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
RD09_RS04245	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
RD09_RS04250	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
RD09_RS04255	COG1181	Belongs to the D-alanine--D-alanine ligase family
RD09_RS04260	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
RD09_RS04270	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
RD09_RS04275	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
RD09_RS04285	COG0739	heme binding
RD09_RS04290	COG0653	protein targeting
RD09_RS04310	COG1028	Short-chain dehydrogenase reductase Sdr
RD09_RS04315	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RD09_RS04320	COG1522	sequence-specific DNA binding
RD09_RS04340	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
RD09_RS04350	COG0557	exoribonuclease II activity
RD09_RS04355	COG3150	esterase
RD09_RS04360	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
RD09_RS04365	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RD09_RS04370	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
RD09_RS04375	COG0511	ligase activity, forming carbon-carbon bonds
RD09_RS04380	COG0439	Biotin carboxylase
RD09_RS04385	COG2264	protein methyltransferase activity
RD09_RS04395	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RD09_RS04420	COG1696	Membrane protein involved in D-alanine export
RD09_RS04425	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RD09_RS04460	COG1522	sequence-specific DNA binding
RD09_RS04475	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
RD09_RS04480	COG0045	succinate-CoA ligase (ADP-forming) activity
RD09_RS04480	COG1042	CoA-binding domain protein
RD09_RS04480	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RD09_RS04490	COG1802	Transcriptional regulator
RD09_RS04495	COG3069	C4-dicarboxylate transmembrane transporter activity
RD09_RS04500	COG0513	Belongs to the DEAD box helicase family
RD09_RS04505	COG0346	lactoylglutathione lyase activity
RD09_RS04510	COG1335	isochorismatase
RD09_RS04515	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RD09_RS04520	COG1116	anion transmembrane transporter activity
RD09_RS04535	COG3028	Belongs to the UPF0307 family
RD09_RS04540	COG0312	modulator of DNA gyrase
RD09_RS04545	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
RD09_RS04550	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
RD09_RS04555	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
RD09_RS04560	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
RD09_RS04570	COG0316	Belongs to the HesB IscA family
RD09_RS04575	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
RD09_RS04590	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
RD09_RS04600	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
RD09_RS04605	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
RD09_RS04620	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
RD09_RS04620	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
RD09_RS04650	COG0583	DNA-binding transcription factor activity
RD09_RS04655	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD09_RS04690	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
RD09_RS04700	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
RD09_RS04705	COG1845	cytochrome c oxidase, subunit III
RD09_RS04710	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
RD09_RS04715	COG0640	Transcriptional regulator
RD09_RS04735	COG3220	belongs to the UPF0276 family
RD09_RS04780	COG1666	GTP binding
RD09_RS04815	COG0312	modulator of DNA gyrase
RD09_RS04820	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
RD09_RS04825	COG3210	domain, Protein
RD09_RS04825	COG3064	Membrane
RD09_RS04825	COG3210	domain, Protein
RD09_RS04825	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
RD09_RS04825	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
RD09_RS04825	COG3064	Membrane
RD09_RS04830	COG0277	FAD linked oxidase domain protein
RD09_RS04835	COG0277	FAD linked oxidase domain protein
RD09_RS04840	COG0277	FAD linked oxidase domain protein
RD09_RS04845	COG0247	lactate metabolic process
RD09_RS04850	COG2819	hydrolase of the alpha beta superfamily
RD09_RS04885	COG0583	DNA-binding transcription factor activity
RD09_RS04890	COG0482	sulfurtransferase activity
RD09_RS04895	COG0730	response to heat
RD09_RS04900	COG0625	glutathione transferase activity
RD09_RS04905	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
RD09_RS04910	COG3909	cytochrome
RD09_RS04950	COG0154	amidase activity
RD09_RS04955	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD09_RS04960	COG1024	Enoyl-CoA hydratase
RD09_RS04975	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RD09_RS04990	COG1028	Short-chain dehydrogenase reductase Sdr
RD09_RS04995	COG1414	Transcriptional regulator
RD09_RS05005	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RD09_RS05010	COG0251	oxidation-reduction process
RD09_RS05015	COG0559	Belongs to the binding-protein-dependent transport system permease family
RD09_RS05035	COG1902	pentaerythritol trinitrate reductase activity
RD09_RS05050	COG0583	DNA-binding transcription factor activity
RD09_RS05060	COG0590	tRNA wobble adenosine to inosine editing
RD09_RS05065	COG2807	transmembrane transport
RD09_RS05085	COG0154	amidase activity
RD09_RS05090	COG0307	riboflavin synthase, alpha
RD09_RS05095	COG3181	Tripartite tricarboxylate transporter family receptor
RD09_RS05100	COG1522	sequence-specific DNA binding
RD09_RS05110	COG0318	PFAM AMP-dependent synthetase and ligase
RD09_RS05120	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RD09_RS05140	COG1063	alcohol dehydrogenase
RD09_RS05165	COG1418	mRNA catabolic process
RD09_RS05170	COG1448	Aminotransferase
RD09_RS05175	COG0583	DNA-binding transcription factor activity
RD09_RS05185	COG0477	Major facilitator Superfamily
RD09_RS05190	COG1028	Short-chain dehydrogenase reductase Sdr
RD09_RS05205	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
RD09_RS05210	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
RD09_RS05215	COG0583	DNA-binding transcription factor activity
RD09_RS05255	COG1028	Short-chain dehydrogenase reductase Sdr
RD09_RS05260	COG1309	transcriptional regulator
RD09_RS05270	COG2982	Protein involved in outer membrane biogenesis
RD09_RS05275	COG2818	Glycosylase
RD09_RS05295	COG1653	transport
RD09_RS05305	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RD09_RS05310	COG3842	ATPase activity
RD09_RS05315	COG0395	ABC-type sugar transport system, permease component
RD09_RS05320	COG1175	transmembrane transport
RD09_RS05340	COG3181	Tripartite tricarboxylate transporter family receptor
RD09_RS05345	COG2186	Transcriptional regulator
RD09_RS05370	COG1454	alcohol dehydrogenase
RD09_RS05390	COG2011	ABC-type metal ion transport system permease component
RD09_RS05395	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
RD09_RS05400	COG1501	Belongs to the glycosyl hydrolase 31 family
RD09_RS05420	COG0318	PFAM AMP-dependent synthetase and ligase
RD09_RS05425	COG1473	amidohydrolase
RD09_RS05435	COG2855	membrane
RD09_RS05445	COG2239	Acts as a magnesium transporter
RD09_RS05465	COG3181	Tripartite tricarboxylate transporter family receptor
RD09_RS05475	COG1722	exodeoxyribonuclease VII activity
RD09_RS05480	COG0142	geranyltranstransferase activity
RD09_RS05485	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
RD09_RS05490	COG1469	GTP cyclohydrolase I activity
RD09_RS05495	COG0360	Binds together with S18 to 16S ribosomal RNA
RD09_RS05500	COG2965	DNA replication, synthesis of RNA primer
RD09_RS05505	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
RD09_RS05510	COG0359	binds to the 23S rRNA
RD09_RS05520	COG0305	Participates in initiation and elongation during chromosome replication
RD09_RS05530	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
RD09_RS05535	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
RD09_RS05540	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
RD09_RS05545	COG3737	Protein of unknown function (DUF498/DUF598)
RD09_RS05550	COG0436	Aminotransferase
RD09_RS05575	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
RD09_RS05605	COG0268	Binds directly to 16S ribosomal RNA
RD09_RS05615	COG0728	peptidoglycan biosynthetic process
RD09_RS05625	COG0563	adenylate kinase activity
RD09_RS05630	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
RD09_RS05635	COG2835	tetraacyldisaccharide 4'-kinase activity
RD09_RS05640	COG1663	tetraacyldisaccharide 4'-kinase activity
RD09_RS05645	COG0848	biopolymer transport protein
RD09_RS05650	COG0811	peptide transport
RD09_RS05660	COG1570	exodeoxyribonuclease VII activity
RD09_RS05665	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
RD09_RS05670	COG0038	chloride channel
RD09_RS05675	COG0183	Belongs to the thiolase family
RD09_RS05685	COG1278	Cold shock
RD09_RS05690	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
RD09_RS05700	COG4953	penicillin-binding protein 1C
RD09_RS05705	COG0542	response to heat
RD09_RS05710	COG2995	paraquat-inducible protein a
RD09_RS05715	COG3008	intermembrane lipid transfer
RD09_RS05715	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
RD09_RS05725	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
RD09_RS05725	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
RD09_RS05725	COG0506	proline dehydrogenase activity
RD09_RS05760	COG2271	Major facilitator Superfamily
RD09_RS05765	COG1309	transcriptional regulator
RD09_RS05775	COG3468	outer membrane autotransporter barrel domain protein
RD09_RS05805	COG0477	Major facilitator Superfamily
RD09_RS05815	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
RD09_RS05820	COG1845	cytochrome c oxidase, subunit III
RD09_RS05825	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
RD09_RS05835	COG1028	Short-chain dehydrogenase reductase Sdr
RD09_RS05855	COG0789	Transcriptional regulator
RD09_RS05880	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
RD09_RS05885	COG0697	spore germination
RD09_RS05895	COG0678	peroxiredoxin activity
RD09_RS05905	COG0412	Dienelactone hydrolase
RD09_RS05915	COG0315	cyclic pyranopterin monophosphate synthase activity
RD09_RS05930	COG0521	Mo-molybdopterin cofactor biosynthetic process
RD09_RS05935	COG0303	'Molybdopterin
RD09_RS05940	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
RD09_RS05960	COG0165	Argininosuccinate lyase
RD09_RS05965	COG0668	transmembrane transport
RD09_RS06010	COG0747	negative chemotaxis
RD09_RS06015	COG0601	transmembrane transport
RD09_RS06020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RD09_RS06025	COG1162	GTPase activity
RD09_RS06030	COG0501	Belongs to the peptidase M48B family
RD09_RS06035	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
RD09_RS06045	COG3327	negative regulation of DNA-templated transcription, initiation
RD09_RS06050	COG3396	Phenylacetate-CoA oxygenase
RD09_RS06055	COG3460	Phenylacetate-CoA oxygenase
RD09_RS06060	COG3396	Phenylacetate-CoA oxygenase
RD09_RS06065	COG2151	metal-sulfur cluster biosynthetic enzyme
RD09_RS06070	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
RD09_RS06080	COG1012	belongs to the aldehyde dehydrogenase family
RD09_RS06085	COG1024	Enoyl-CoA hydratase
RD09_RS06090	COG2050	protein possibly involved in aromatic compounds catabolism
RD09_RS06100	COG3539	Fimbrial protein
RD09_RS06115	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
RD09_RS06120	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
RD09_RS06120	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
RD09_RS06125	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
RD09_RS06130	COG0047	phosphoribosylformylglycinamidine synthase activity
RD09_RS06130	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
RD09_RS06135	COG3064	Membrane
RD09_RS06135	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
RD09_RS06135	COG3210	domain, Protein
RD09_RS06160	COG0235	Class ii aldolase
RD09_RS06165	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
RD09_RS06170	COG0720	synthase
RD09_RS06175	COG0602	queuosine metabolic process
RD09_RS06200	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RD09_RS06235	COG3181	Tripartite tricarboxylate transporter family receptor
RD09_RS06265	COG3842	ATPase activity
RD09_RS06275	COG0395	ABC-type sugar transport system, permease component
RD09_RS06305	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RD09_RS06310	COG0420	3'-5' exonuclease activity
RD09_RS06335	COG2197	response regulator
RD09_RS06360	COG0519	Catalyzes the synthesis of GMP from XMP
RD09_RS06360	COG0518	GMP synthase (glutamine-hydrolyzing) activity
RD09_RS06370	COG3550	peptidyl-serine autophosphorylation
RD09_RS06380	COG0477	Major facilitator Superfamily
RD09_RS06395	COG1228	amidohydrolase
RD09_RS06405	COG1116	anion transmembrane transporter activity
RD09_RS06410	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RD09_RS06445	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
RD09_RS06460	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
RD09_RS06490	COG2814	Major facilitator Superfamily
RD09_RS06505	COG1280	lysine exporter protein (LysE YggA)
RD09_RS06520	COG0747	negative chemotaxis
RD09_RS06525	COG0601	transmembrane transport
RD09_RS06530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RD09_RS06535	COG4172	Belongs to the ABC transporter superfamily
RD09_RS06540	COG1609	Transcriptional regulator
RD09_RS06565	COG0586	Pfam SNARE associated Golgi protein
RD09_RS06575	COG0500	methyltransferase
RD09_RS06590	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RD09_RS06600	COG0756	dUTP diphosphatase activity
RD09_RS06610	COG0291	Belongs to the bacterial ribosomal protein bL35 family
RD09_RS06615	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
RD09_RS06620	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
RD09_RS06625	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RD09_RS06625	COG0072	phenylalanine-tRNA ligase activity
RD09_RS06630	COG0776	regulation of translation
RD09_RS06700	COG0540	Belongs to the ATCase OTCase family
RD09_RS06705	COG2974	May be involved in recombination
RD09_RS06715	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD09_RS06720	COG0583	DNA-binding transcription factor activity
RD09_RS06740	COG1028	Short-chain dehydrogenase reductase Sdr
RD09_RS06755	COG3842	ATPase activity
RD09_RS06760	COG1250	3-hydroxyacyl-CoA dehydrogenase
RD09_RS06760	COG1024	Enoyl-CoA hydratase
RD09_RS06780	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
RD09_RS06785	COG2137	regulation of response to DNA damage stimulus
RD09_RS06795	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
RD09_RS06805	COG0045	succinate-CoA ligase (ADP-forming) activity
RD09_RS06810	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
RD09_RS06815	COG0861	Integral membrane protein TerC family
RD09_RS06820	COG0861	Integral membrane protein TerC family
RD09_RS06825	COG0181	hydroxymethylbilane synthase activity
RD09_RS06885	COG4964	Belongs to the GSP D family
RD09_RS06915	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
RD09_RS06925	COG0583	DNA-binding transcription factor activity
RD09_RS06935	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RD09_RS06940	COG4311	Sarcosine oxidase, delta subunit
RD09_RS06945	COG0404	The glycine cleavage system catalyzes the degradation of glycine
RD09_RS06945	COG0446	pyridine nucleotide-disulphide oxidoreductase
RD09_RS06980	COG0812	UDP-N-acetylmuramate dehydrogenase activity
RD09_RS06985	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
RD09_RS06990	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
RD09_RS06995	COG0735	belongs to the Fur family
RD09_RS07000	COG0497	DNA recombination
RD09_RS07005	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
RD09_RS07010	COG1420	regulation of RNA biosynthetic process
RD09_RS07015	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
RD09_RS07025	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
RD09_RS07035	COG0443	Heat shock 70 kDa protein
RD09_RS07045	COG0612	Peptidase, M16
RD09_RS07065	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
RD09_RS07110	COG0745	RESPONSE REGULATOR receiver
RD09_RS07115	COG2205	protein histidine kinase activity
RD09_RS07120	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
RD09_RS07125	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
RD09_RS07130	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
RD09_RS07140	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RD09_RS07160	COG1193	negative regulation of DNA recombination
RD09_RS07165	COG0492	ferredoxin-NADP+ reductase activity
RD09_RS07170	COG1674	ftsk spoiiie
RD09_RS07175	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
RD09_RS07180	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
RD09_RS07185	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
RD09_RS07210	COG3706	GGDEF domain
RD09_RS07230	COG2814	Major facilitator Superfamily
RD09_RS07260	COG3486	L-lysine 6-monooxygenase (NADPH) activity
RD09_RS07275	COG1028	Short-chain dehydrogenase reductase Sdr
RD09_RS07285	COG3022	response to hydroperoxide
RD09_RS07295	COG1289	transmembrane transporter activity
RD09_RS07315	COG0635	Involved in the biosynthesis of porphyrin-containing compound
RD09_RS07325	COG2197	response regulator
RD09_RS07330	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
RD09_RS07335	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
RD09_RS07340	COG0189	ligase activity
RD09_RS07350	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
RD09_RS07355	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
RD09_RS07365	COG2423	ornithine cyclodeaminase activity
RD09_RS07375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RD09_RS07380	COG0765	amino acid transport
RD09_RS07385	COG0765	amino acid transport
RD09_RS07390	COG1126	abc transporter atp-binding protein
RD09_RS07445	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
RD09_RS07455	COG2944	sequence-specific DNA binding
RD09_RS07460	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
RD09_RS07465	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
RD09_RS07470	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
RD09_RS07475	COG0009	L-threonylcarbamoyladenylate synthase
RD09_RS07480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RD09_RS07485	COG1414	Transcriptional regulator
RD09_RS07500	COG0765	amino acid transport
RD09_RS07505	COG1126	abc transporter atp-binding protein
RD09_RS07510	COG0028	Belongs to the TPP enzyme family
RD09_RS07525	COG0028	Belongs to the TPP enzyme family
RD09_RS07530	COG0583	DNA-binding transcription factor activity
RD09_RS07535	COG4974	Belongs to the 'phage' integrase family
RD09_RS07540	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
RD09_RS07545	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
RD09_RS07560	COG1686	Belongs to the peptidase S11 family
RD09_RS07570	COG2814	Major facilitator Superfamily
RD09_RS07580	COG1074	ATP-dependent DNA helicase activity
RD09_RS07590	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
RD09_RS07595	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
RD09_RS07600	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
RD09_RS07620	COG2321	neutral zinc metallopeptidase
RD09_RS07625	COG0009	L-threonylcarbamoyladenylate synthase
RD09_RS07665	COG3360	Dodecin
RD09_RS07670	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
RD09_RS07675	COG2850	peptidyl-arginine hydroxylation
RD09_RS07680	COG3539	Fimbrial protein
RD09_RS07685	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
RD09_RS07690	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RD09_RS07695	COG1994	Peptidase M50
RD09_RS07705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RD09_RS07710	COG0765	amino acid transport
RD09_RS07715	COG1126	abc transporter atp-binding protein
RD09_RS07720	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
RD09_RS07725	COG1758	RNA polymerase activity
RD09_RS07730	COG0194	GDP metabolic process
RD09_RS07735	COG3258	Cytochrome c
RD09_RS07740	COG2863	cytochrome
RD09_RS07745	COG1028	Short-chain dehydrogenase reductase Sdr
RD09_RS07750	COG0791	NLP P60 protein
RD09_RS07755	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
RD09_RS07775	COG1561	YicC-like family, N-terminal region
RD09_RS07780	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
RD09_RS07795	COG2200	EAL domain
RD09_RS07795	COG2199	diguanylate cyclase activity
RD09_RS07800	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
RD09_RS07810	COG0635	Involved in the biosynthesis of porphyrin-containing compound
RD09_RS07815	COG0174	glutamine synthetase
RD09_RS07825	COG2204	response regulator
RD09_RS07830	COG0583	DNA-binding transcription factor activity
RD09_RS07835	COG1741	Belongs to the pirin family
RD09_RS07840	COG1741	Belongs to the pirin family
RD09_RS07850	COG3842	ATPase activity
RD09_RS07855	COG1178	ABC-type Fe3 transport system permease component
RD09_RS07860	COG1840	ABC-type Fe3 transport system, periplasmic component
RD09_RS07870	COG0583	DNA-binding transcription factor activity
RD09_RS07880	COG0656	L-ascorbic acid biosynthetic process
RD09_RS07895	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
RD09_RS07900	COG0583	DNA-binding transcription factor activity
RD09_RS07915	COG0783	Belongs to the Dps family
RD09_RS07950	COG0438	transferase activity, transferring glycosyl groups
RD09_RS07965	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
RD09_RS07990	COG0300	oxidoreductase activity
RD09_RS08035	COG0861	Integral membrane protein TerC family
RD09_RS08040	COG1028	Short-chain dehydrogenase reductase Sdr
RD09_RS08060	COG0714	Associated with various cellular activities
RD09_RS08090	COG3119	arylsulfatase activity
RD09_RS08115	COG2197	response regulator
RD09_RS08125	COG2944	sequence-specific DNA binding
RD09_RS08130	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
RD09_RS08135	COG0625	glutathione transferase activity
RD09_RS08165	COG0179	Fumarylacetoacetate (FAA) hydrolase
RD09_RS08170	COG1028	Short-chain dehydrogenase reductase Sdr
RD09_RS08215	COG0431	NADPH-dependent FMN reductase
RD09_RS08245	COG1028	Short-chain dehydrogenase reductase Sdr
RD09_RS08250	COG0583	DNA-binding transcription factor activity
RD09_RS08265	COG3181	Tripartite tricarboxylate transporter family receptor
RD09_RS08270	COG2111	Na H antiporter
RD09_RS08270	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
RD09_RS08275	COG1006	Multisubunit Na H antiporter MnhC subunit
RD09_RS08280	COG0651	ATP synthesis coupled electron transport
RD09_RS08285	COG1863	multisubunit Na H antiporter MnhE subunit
RD09_RS08290	COG2212	antiporter activity
RD09_RS08315	COG0590	tRNA wobble adenosine to inosine editing
RD09_RS08320	COG1619	proteins homologs of microcin C7 resistance protein MccF
RD09_RS08325	COG1024	Enoyl-CoA hydratase
RD09_RS08340	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
RD09_RS08345	COG0488	(ABC) transporter
RD09_RS08385	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
RD09_RS08385	COG1017	nitric oxide dioxygenase activity
RD09_RS08390	COG1959	2 iron, 2 sulfur cluster binding
RD09_RS08395	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RD09_RS08415	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
RD09_RS08420	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
RD09_RS08425	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
RD09_RS08430	COG0084	hydrolase, TatD family'
RD09_RS08445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RD09_RS08455	COG1126	abc transporter atp-binding protein
RD09_RS08460	COG0010	Belongs to the arginase family
RD09_RS08465	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
RD09_RS08470	COG1012	belongs to the aldehyde dehydrogenase family
RD09_RS08480	COG0028	Belongs to the TPP enzyme family
RD09_RS08490	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
RD09_RS08490	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
RD09_RS08500	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
RD09_RS08515	COG3189	MarR family transcriptional regulator
RD09_RS08540	COG4336	lyase activity
RD09_RS08550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RD09_RS08550	COG2205	protein histidine kinase activity
RD09_RS08555	COG2197	response regulator
RD09_RS08560	COG3064	Membrane
RD09_RS08560	COG3210	domain, Protein
RD09_RS08560	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
RD09_RS08570	COG3121	Chaperone
RD09_RS08575	COG3188	usher protein
RD09_RS08580	COG3539	Fimbrial protein
RD09_RS08585	COG2831	hemolysin activation secretion protein
RD09_RS08600	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
RD09_RS08625	COG0583	DNA-binding transcription factor activity
RD09_RS08650	COG0668	transmembrane transport
RD09_RS08670	COG0483	inositol monophosphate 1-phosphatase activity
RD09_RS08675	COG1253	flavin adenine dinucleotide binding
RD09_RS08680	COG1968	undecaprenyl-diphosphatase activity
RD09_RS08685	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
RD09_RS08700	COG0215	cysteine-tRNA ligase activity
RD09_RS08710	COG0825	malonyl-CoA metabolic process
RD09_RS08720	COG0037	tRNA processing
RD09_RS08725	COG0527	aspartate kinase activity
RD09_RS08750	COG1250	3-hydroxyacyl-CoA dehydrogenase
RD09_RS08755	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
RD09_RS08755	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
RD09_RS08770	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
RD09_RS08775	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
RD09_RS08780	COG1028	Short-chain dehydrogenase reductase Sdr
RD09_RS08790	COG0583	DNA-binding transcription factor activity
RD09_RS08820	COG3842	ATPase activity
RD09_RS08830	COG1902	pentaerythritol trinitrate reductase activity
RD09_RS08830	COG0446	pyridine nucleotide-disulphide oxidoreductase
RD09_RS08835	COG1414	Transcriptional regulator
RD09_RS08840	COG1832	CoA-binding protein
RD09_RS08850	COG0251	oxidation-reduction process
RD09_RS08875	COG1902	pentaerythritol trinitrate reductase activity
RD09_RS08885	COG1215	transferase activity, transferring glycosyl groups
RD09_RS08890	COG0726	polysaccharide deacetylase
RD09_RS08890	COG1649	PFAM Uncharacterised BCR, COG1649
RD09_RS08910	COG1846	Transcriptional regulator
RD09_RS08930	COG0166	Belongs to the GPI family
RD09_RS08935	COG1045	serine acetyltransferase
RD09_RS08945	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
RD09_RS08950	COG0483	inositol monophosphate 1-phosphatase activity
RD09_RS08955	COG1012	belongs to the aldehyde dehydrogenase family
RD09_RS08960	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
RD09_RS08975	COG0210	DNA helicase
RD09_RS08980	COG0598	Magnesium transport protein CorA
RD09_RS08990	COG0747	negative chemotaxis
RD09_RS08995	COG0601	transmembrane transport
RD09_RS09000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RD09_RS09005	COG4172	Belongs to the ABC transporter superfamily
RD09_RS09010	COG1846	Transcriptional regulator
RD09_RS09060	COG4964	Belongs to the GSP D family
RD09_RS09100	COG2204	response regulator
RD09_RS09115	COG1595	DNA-templated transcription, initiation
RD09_RS09125	COG3474	cytochrome
RD09_RS09130	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
RD09_RS09145	COG3384	dioxygenase
RD09_RS09150	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
RD09_RS09175	COG2885	chlorophyll binding
RD09_RS09210	COG0697	spore germination
RD09_RS09215	COG0730	response to heat
RD09_RS09230	COG0583	DNA-binding transcription factor activity
RD09_RS09235	COG0427	acetyl-CoA hydrolase
RD09_RS09280	COG3468	outer membrane autotransporter barrel domain protein
RD09_RS09285	COG0424	maF-like protein
RD09_RS09290	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
RD09_RS09295	COG0799	negative regulation of ribosome biogenesis
RD09_RS09300	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
RD09_RS09305	COG0408	coproporphyrinogen oxidase activity
RD09_RS09310	COG0151	Belongs to the GarS family
RD09_RS09315	COG0217	transcriptional regulatory protein
RD09_RS09320	COG0433	COG0433 Predicted ATPase
RD09_RS09325	COG1115	amino acid carrier protein
RD09_RS09330	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
RD09_RS09340	COG1012	belongs to the aldehyde dehydrogenase family
RD09_RS09365	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
RD09_RS09380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RD09_RS09390	COG0747	negative chemotaxis
RD09_RS09400	COG0473	3-isopropylmalate dehydrogenase activity
RD09_RS09405	COG2814	Major facilitator Superfamily
RD09_RS09410	COG1566	PFAM secretion protein HlyD family protein
RD09_RS09420	COG1846	Transcriptional regulator
RD09_RS09430	COG0697	spore germination
RD09_RS09440	COG0501	Belongs to the peptidase M48B family
RD09_RS09460	COG0583	DNA-binding transcription factor activity
RD09_RS09465	COG3842	ATPase activity
RD09_RS09470	COG1178	ABC-type Fe3 transport system permease component
RD09_RS09475	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RD09_RS09480	COG1840	ABC-type Fe3 transport system, periplasmic component
RD09_RS09485	COG0492	ferredoxin-NADP+ reductase activity
RD09_RS09505	COG2233	PERMEase
RD09_RS09510	COG0840	transmembrane signaling receptor activity
RD09_RS09515	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
RD09_RS09545	COG4789	Type iii secretion
RD09_RS09610	COG4669	(LipO)protein
RD09_RS09645	COG4790	Type iii secretion
RD09_RS09650	COG4794	Type iii secretion
RD09_RS09655	COG4791	protein targeting
RD09_RS09660	COG4792	protein secretion
RD09_RS09675	COG1595	DNA-templated transcription, initiation
RD09_RS09695	COG2208	phosphoserine phosphatase activity
RD09_RS09695	COG2770	Histidine kinase
RD09_RS09705	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
RD09_RS09710	COG2172	sigma factor antagonist activity
RD09_RS09715	COG1366	Belongs to the anti-sigma-factor antagonist family
RD09_RS09720	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RD09_RS09750	COG2358	TRAP transporter, solute receptor (TAXI family
RD09_RS09755	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
RD09_RS09785	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RD09_RS09795	COG2252	PERMEase
RD09_RS09800	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
RD09_RS09810	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
RD09_RS09815	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
RD09_RS09845	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
RD09_RS09850	COG0789	Transcriptional regulator
RD09_RS09860	COG0678	peroxiredoxin activity
RD09_RS09860	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
RD09_RS09870	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
RD09_RS09875	COG0584	glycerophosphoryl diester phosphodiesterase
RD09_RS09880	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
RD09_RS09890	COG4181	ATPase activity
RD09_RS09905	COG2823	Periplasmic or secreted lipoprotein
RD09_RS09915	COG3237	CsbD-like
RD09_RS09920	COG1181	Belongs to the D-alanine--D-alanine ligase family
RD09_RS09920	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
RD09_RS09925	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
RD09_RS09925	COG0189	ligase activity
RD09_RS09945	COG2833	Protein of unknown function (DUF455)
RD09_RS09950	COG2951	lytic endotransglycosylase activity
RD09_RS09965	COG1522	sequence-specific DNA binding
RD09_RS09975	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
RD09_RS09980	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
RD09_RS09985	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
RD09_RS09990	COG0196	riboflavin kinase activity
RD09_RS09995	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
RD09_RS09995	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
RD09_RS10015	COG0210	DNA helicase
RD09_RS10020	COG4771	TonB-dependent receptor
RD09_RS10025	COG0488	(ABC) transporter
RD09_RS10030	COG2890	protein-(glutamine-N5) methyltransferase activity
RD09_RS10035	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RD09_RS10040	COG2171	N-acyltransferase activity
RD09_RS10075	COG1278	Cold shock
RD09_RS10085	COG1278	Cold shock
RD09_RS10095	COG0544	peptidyl-prolyl cis-trans isomerase activity
RD09_RS10100	COG0740	serine-type endopeptidase activity
RD09_RS10105	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
RD09_RS10110	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
RD09_RS10115	COG0583	DNA-binding transcription factor activity
RD09_RS10120	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD09_RS10135	COG1024	Enoyl-CoA hydratase
RD09_RS10145	COG0183	Belongs to the thiolase family
RD09_RS10150	COG1028	Short-chain dehydrogenase reductase Sdr
RD09_RS10155	COG1960	acyl-CoA dehydrogenase activity
RD09_RS10170	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
RD09_RS10195	COG3468	outer membrane autotransporter barrel domain protein
RD09_RS10200	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
RD09_RS10210	COG0556	nucleotide-excision repair
RD09_RS10215	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
RD09_RS10225	COG1104	cysteine desulfurase activity
RD09_RS10230	COG0822	iron-sulfur transferase activity
RD09_RS10235	COG0316	Belongs to the HesB IscA family
RD09_RS10240	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
RD09_RS10245	COG0443	Heat shock 70 kDa protein
RD09_RS10250	COG0633	Ferredoxin
RD09_RS10270	COG1024	Enoyl-CoA hydratase
RD09_RS10285	COG3395	kinase activity
RD09_RS10290	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
RD09_RS10305	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
RD09_RS10315	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RD09_RS10340	COG0747	negative chemotaxis
RD09_RS10345	COG0601	transmembrane transport
RD09_RS10350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RD09_RS10355	COG4172	Belongs to the ABC transporter superfamily
RD09_RS10360	COG0154	amidase activity
RD09_RS10405	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
RD09_RS10410	COG0425	Belongs to the sulfur carrier protein TusA family
RD09_RS10420	COG0228	four-way junction DNA binding
RD09_RS10425	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
RD09_RS10430	COG0336	Belongs to the RNA methyltransferase TrmD family
RD09_RS10435	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
RD09_RS10455	COG0642	Histidine kinase
RD09_RS10470	COG0525	valine-tRNA ligase activity
RD09_RS10475	COG0105	UTP biosynthetic process
RD09_RS10480	COG0820	rRNA (adenine-C2-)-methyltransferase activity
RD09_RS10490	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
RD09_RS10495	COG0124	histidyl-tRNA synthetase
RD09_RS10500	COG2976	Protein conserved in bacteria
RD09_RS10505	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
RD09_RS10510	COG1160	GTP binding
RD09_RS10515	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
RD09_RS10520	COG1923	regulation of RNA biosynthetic process
RD09_RS10525	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
RD09_RS10530	COG0330	HflC and HflK could
RD09_RS10535	COG0330	HflC and HflK could
RD09_RS10540	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
RD09_RS10545	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
RD09_RS10550	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
RD09_RS10555	COG0828	Belongs to the bacterial ribosomal protein bS21 family
RD09_RS10565	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
RD09_RS10595	COG0628	permease
RD09_RS10600	COG0842	Transport permease protein
RD09_RS10605	COG1131	(ABC) transporter
RD09_RS10675	COG0156	8-amino-7-oxononanoate synthase activity
RD09_RS10685	COG4106	trans-aconitate 2-methyltransferase activity
RD09_RS10685	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
RD09_RS10690	COG1380	Effector of murein hydrolase LrgA
RD09_RS10695	COG1346	cytolysis
RD09_RS10710	COG3284	Transcriptional regulator
RD09_RS10715	COG1012	belongs to the aldehyde dehydrogenase family
RD09_RS10730	COG2733	membrane
RD09_RS10735	COG0583	DNA-binding transcription factor activity
RD09_RS10740	COG0384	phenazine biosynthesis protein PhzF
RD09_RS10745	COG5507	3-demethylubiquinone-9 3-methyltransferase
RD09_RS10750	COG2169	Transcriptional regulator
RD09_RS10780	COG0659	secondary active sulfate transmembrane transporter activity
RD09_RS10805	COG1132	(ABC) transporter
RD09_RS10850	COG2207	Transcriptional regulator
RD09_RS10980	COG2346	COG2346, Truncated hemoglobins
RD09_RS11005	COG0583	DNA-binding transcription factor activity
RD09_RS11010	COG4692	amylo-alpha-1,6-glucosidase activity
RD09_RS11020	COG0183	Belongs to the thiolase family
RD09_RS11035	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD09_RS11040	COG0633	Ferredoxin
RD09_RS11050	COG1024	Enoyl-CoA hydratase
RD09_RS11060	COG4638	Rieske (2fe-2S)
RD09_RS11070	COG0559	Belongs to the binding-protein-dependent transport system permease family
RD09_RS11090	COG2224	Isocitrate lyase
RD09_RS11095	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
RD09_RS11095	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
RD09_RS11110	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
RD09_RS11115	COG0322	excinuclease ABC activity
RD09_RS11120	COG1472	Belongs to the glycosyl hydrolase 3 family
RD09_RS11125	COG0736	holo-[acyl-carrier-protein] synthase activity
RD09_RS11130	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
RD09_RS11140	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RD09_RS11145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RD09_RS11170	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
RD09_RS11185	COG2032	superoxide dismutase activity
RD09_RS11200	COG1024	Enoyl-CoA hydratase
RD09_RS11210	COG1802	Transcriptional regulator
RD09_RS11220	COG0183	Belongs to the thiolase family
RD09_RS11225	COG1942	4-Oxalocrotonate Tautomerase
RD09_RS11235	COG4176	ABC-type proline glycine betaine transport system permease component
RD09_RS11250	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
RD09_RS11255	COG2814	Major facilitator Superfamily
RD09_RS11260	COG0227	Belongs to the bacterial ribosomal protein bL28 family
RD09_RS11265	COG0267	Belongs to the bacterial ribosomal protein bL33 family
RD09_RS11295	COG2814	Major facilitator Superfamily
RD09_RS11300	COG0495	leucyl-tRNA aminoacylation
RD09_RS11315	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
RD09_RS11325	COG0154	amidase activity
RD09_RS11330	COG1250	3-hydroxyacyl-CoA dehydrogenase
RD09_RS11380	COG1530	ribonuclease E activity
RD09_RS11385	COG0077	Prephenate dehydratase
RD09_RS11400	COG1132	(ABC) transporter
RD09_RS11405	COG0859	PFAM glycosyl transferase family 9
RD09_RS11430	COG2194	sulfuric ester hydrolase activity
RD09_RS11435	COG0438	transferase activity, transferring glycosyl groups
RD09_RS11440	COG0463	Glycosyl transferase, family 2
RD09_RS11445	COG0726	polysaccharide deacetylase
RD09_RS11450	COG0438	transferase activity, transferring glycosyl groups
RD09_RS11465	COG1643	Atp-dependent helicase
RD09_RS11470	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
RD09_RS11470	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
RD09_RS11475	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
RD09_RS11485	COG0704	Plays a role in the regulation of phosphate uptake
RD09_RS11490	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
RD09_RS11495	COG1960	acyl-CoA dehydrogenase activity
RD09_RS11520	COG1177	transmembrane transport
RD09_RS11525	COG1176	ABC-type spermidine putrescine transport system, permease component I
RD09_RS11530	COG3842	ATPase activity
RD09_RS11535	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
RD09_RS11550	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
RD09_RS11555	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
RD09_RS11565	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
RD09_RS11565	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
RD09_RS11585	COG0372	Belongs to the citrate synthase family
RD09_RS11590	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
RD09_RS11595	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
RD09_RS11600	COG1053	succinate dehydrogenase
RD09_RS11605	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
RD09_RS11610	COG2009	succinate dehydrogenase
RD09_RS11615	COG2188	Transcriptional regulator
RD09_RS11620	COG0039	L-malate dehydrogenase activity
RD09_RS11650	COG1981	membrane
RD09_RS11675	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RD09_RS11685	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
RD09_RS11715	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
RD09_RS11720	COG0148	phosphopyruvate hydratase activity
RD09_RS11730	COG2877	3-deoxy-8-phosphooctulonate synthase activity
RD09_RS11735	COG0504	CTP synthase activity
RD09_RS11760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RD09_RS11770	COG0747	negative chemotaxis
RD09_RS11775	COG4172	Belongs to the ABC transporter superfamily
RD09_RS11780	COG1446	asparaginase
RD09_RS11810	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
RD09_RS11825	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
RD09_RS11830	COG0697	spore germination
RD09_RS11835	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RD09_RS11845	COG3193	protein, possibly involved in utilization of glycolate and propanediol
RD09_RS11850	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RD09_RS11855	COG0791	NLP P60 protein
RD09_RS11870	COG0583	DNA-binding transcription factor activity
RD09_RS11885	COG0583	DNA-binding transcription factor activity
RD09_RS11895	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
RD09_RS11910	COG0670	Belongs to the BI1 family
RD09_RS11915	COG3181	Tripartite tricarboxylate transporter family receptor
RD09_RS11930	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
RD09_RS11940	COG1381	Involved in DNA repair and RecF pathway recombination
RD09_RS11945	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
RD09_RS11950	COG0571	ribonuclease III activity
RD09_RS11955	COG0681	Belongs to the peptidase S26 family
RD09_RS11960	COG0481	GTPase activity
RD09_RS11965	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RD09_RS11990	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
RD09_RS11995	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RD09_RS12010	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
RD09_RS12015	COG0416	fatty acid biosynthetic process
RD09_RS12020	COG0333	Belongs to the bacterial ribosomal protein bL32 family
RD09_RS12025	COG1399	metal-binding, possibly nucleic acid-binding protein
RD09_RS12030	COG0424	maF-like protein
RD09_RS12040	COG3023	N-Acetylmuramoyl-L-alanine amidase
RD09_RS12045	COG1289	transmembrane transporter activity
RD09_RS12055	COG3022	response to hydroperoxide
RD09_RS12070	COG0135	phosphoribosylanthranilate isomerase activity
RD09_RS12085	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
RD09_RS12090	COG0101	tRNA pseudouridine synthase activity
RD09_RS12100	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
RD09_RS12105	COG0473	3-isopropylmalate dehydrogenase activity
RD09_RS12110	COG0066	3-isopropylmalate dehydratase activity
RD09_RS12115	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
RD09_RS12125	COG1122	ATPase activity
RD09_RS12155	COG0437	4 iron, 4 sulfur cluster binding
RD09_RS12160	COG0243	molybdopterin cofactor binding
RD09_RS12160	COG3383	formate dehydrogenase (NAD+) activity
RD09_RS12190	COG0489	protein tyrosine kinase activity
RD09_RS12195	COG0746	molybdenum cofactor guanylyltransferase activity
RD09_RS12200	COG0303	'Molybdopterin
RD09_RS12205	COG1763	Mo-molybdopterin cofactor biosynthetic process
RD09_RS12215	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
RD09_RS12220	COG5001	Diguanylate cyclase
RD09_RS12240	COG3842	ATPase activity
RD09_RS12250	COG0406	alpha-ribazole phosphatase activity
RD09_RS12260	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
RD09_RS12265	COG0505	Belongs to the CarA family
RD09_RS12270	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
RD09_RS12300	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
RD09_RS12305	COG1960	acyl-CoA dehydrogenase activity
RD09_RS12315	COG2867	negative regulation of translational initiation
RD09_RS12325	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
RD09_RS12330	COG3706	GGDEF domain
RD09_RS12335	COG0330	HflC and HflK could
RD09_RS12350	COG0518	GMP synthase (glutamine-hydrolyzing) activity
RD09_RS12350	COG0519	Catalyzes the synthesis of GMP from XMP
RD09_RS12360	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
RD09_RS12365	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RD09_RS12370	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
RD09_RS12375	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
RD09_RS12385	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
RD09_RS12390	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
RD09_RS12395	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
RD09_RS12400	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
RD09_RS12405	COG0750	zinc metalloprotease
RD09_RS12410	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
RD09_RS12420	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
RD09_RS12425	COG0233	cytoplasmic translational termination
RD09_RS12430	COG0528	UMP kinase activity
RD09_RS12435	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
RD09_RS12440	COG0052	Belongs to the universal ribosomal protein uS2 family
RD09_RS12445	COG0024	Methionine aminopeptidase
RD09_RS12450	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
RD09_RS12480	COG0285	dihydrofolate synthase activity
RD09_RS12515	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
RD09_RS12525	COG1677	Flagellar hook-basal body complex protein FliE
RD09_RS12535	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
RD09_RS12540	COG1317	bacterial-type flagellum organization
RD09_RS12545	COG1157	protein secretion by the type III secretion system
RD09_RS12570	COG1580	Controls the rotational direction of flagella during chemotaxis
RD09_RS12590	COG1338	Plays a role in the flagellum-specific transport system
RD09_RS12610	COG0840	transmembrane signaling receptor activity
RD09_RS12615	COG0840	transmembrane signaling receptor activity
RD09_RS12620	COG0840	transmembrane signaling receptor activity
RD09_RS12630	COG1256	bacterial-type flagellum assembly
RD09_RS12640	COG1706	bacterial-type flagellum-dependent cell motility
RD09_RS12645	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
RD09_RS12660	COG1749	Flagellar hook protein flgE
RD09_RS12670	COG1558	bacterial-type flagellum-dependent cell motility
RD09_RS12675	COG1815	bacterial-type flagellum-dependent cell motility
RD09_RS12715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RD09_RS12720	COG0765	amino acid transport
RD09_RS12725	COG1126	abc transporter atp-binding protein
RD09_RS12740	COG4948	Mandelate Racemase Muconate Lactonizing
RD09_RS12745	COG3181	Tripartite tricarboxylate transporter family receptor
RD09_RS12755	COG0066	3-isopropylmalate dehydratase activity
RD09_RS12770	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD09_RS12780	COG3181	Tripartite tricarboxylate transporter family receptor
RD09_RS12790	COG1802	Transcriptional regulator
RD09_RS12805	COG0583	DNA-binding transcription factor activity
RD09_RS12825	COG1695	Transcriptional regulator
RD09_RS12830	COG3568	Endonuclease Exonuclease Phosphatase
RD09_RS12835	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RD09_RS12850	COG0392	lysyltransferase activity
RD09_RS12890	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
RD09_RS12900	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
RD09_RS12910	COG1640	4-alpha-glucanotransferase
RD09_RS12925	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
RD09_RS12955	COG0667	Aldo Keto reductase
RD09_RS12970	COG2259	Doxx family
RD09_RS13000	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD09_RS13020	COG0386	Belongs to the glutathione peroxidase family
RD09_RS13025	COG0625	glutathione transferase activity
RD09_RS13040	COG0095	Lipoate-protein ligase
RD09_RS13055	COG0688	phosphatidylethanolamine metabolic process
RD09_RS13065	COG1464	Belongs to the NlpA lipoprotein family
RD09_RS13080	COG2363	Small membrane protein
RD09_RS13105	COG3842	ATPase activity
RD09_RS13110	COG0395	ABC-type sugar transport system, permease component
RD09_RS13115	COG1175	transmembrane transport
RD09_RS13120	COG1653	transport
RD09_RS13130	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
RD09_RS13145	COG0559	Belongs to the binding-protein-dependent transport system permease family
RD09_RS13165	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
RD09_RS13180	COG0697	spore germination
RD09_RS13190	COG2311	Membrane
RD09_RS13215	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
RD09_RS13225	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
RD09_RS13230	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
RD09_RS13235	COG1760	l-serine dehydratase
RD09_RS13240	COG1283	sodium-dependent phosphate transmembrane transporter activity
RD09_RS13245	COG0412	Dienelactone hydrolase
RD09_RS13260	COG1611	Belongs to the LOG family
RD09_RS13280	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
RD09_RS13285	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
RD09_RS13290	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
RD09_RS13295	COG0195	Participates in both transcription termination and antitermination
RD09_RS13295	COG2251	uridine kinase activity
RD09_RS13300	COG0779	Required for maturation of 30S ribosomal subunits
RD09_RS13305	COG1187	pseudouridine synthase activity
RD09_RS13310	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
RD09_RS13320	COG0583	DNA-binding transcription factor activity
RD09_RS13330	COG0523	cobalamin synthesis protein
RD09_RS13350	COG0625	glutathione transferase activity
RD09_RS13355	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
RD09_RS13360	COG1047	Peptidyl-prolyl cis-trans
RD09_RS13365	COG2003	Belongs to the UPF0758 family
RD09_RS13370	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
RD09_RS13375	COG3483	tryptophan 2,3-dioxygenase activity
RD09_RS13380	COG0254	rRNA binding
RD09_RS13390	COG0534	Mate efflux family protein
RD09_RS13410	COG2304	oxidoreductase activity
RD09_RS13430	COG1028	Short-chain dehydrogenase reductase Sdr
RD09_RS13435	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
RD09_RS13440	COG1562	ergosterol biosynthetic process
RD09_RS13445	COG1562	ergosterol biosynthetic process
RD09_RS13450	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
RD09_RS13450	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
RD09_RS13455	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
RD09_RS13465	COG0842	Transport permease protein
RD09_RS13470	COG1131	(ABC) transporter
RD09_RS13490	COG1477	protein flavinylation
RD09_RS13505	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
RD09_RS13520	COG5564	TIM-barrel signal transduction protein
RD09_RS13525	COG5441	Belongs to the UPF0261 family
RD09_RS13535	COG3468	outer membrane autotransporter barrel domain protein
RD09_RS13540	COG3468	outer membrane autotransporter barrel domain protein
RD09_RS13550	COG0542	response to heat
RD09_RS13555	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RD09_RS13570	COG0494	nUDIX hydrolase
RD09_RS13575	COG3530	Putative quorum-sensing-regulated virulence factor
RD09_RS13585	COG1595	DNA-templated transcription, initiation
RD09_RS13590	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RD09_RS13625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RD09_RS13630	COG0765	amino acid transport
RD09_RS13635	COG0765	amino acid transport
RD09_RS13660	COG2988	succinylglutamate desuccinylase activity
RD09_RS13685	COG3181	Tripartite tricarboxylate transporter family receptor
RD09_RS13690	COG2084	Dehydrogenase
RD09_RS13705	COG1619	proteins homologs of microcin C7 resistance protein MccF
RD09_RS13720	COG2814	Major facilitator Superfamily
RD09_RS13730	COG0583	DNA-binding transcription factor activity
RD09_RS13770	COG0672	)-iron permease
RD09_RS13785	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
RD09_RS13790	COG1028	Short-chain dehydrogenase reductase Sdr
RD09_RS13795	COG3243	poly(R)-hydroxyalkanoic acid synthase
RD09_RS13805	COG0564	pseudouridine synthase activity
RD09_RS13815	COG1199	ATP-dependent helicase activity
RD09_RS13820	COG2183	response to ionizing radiation
RD09_RS13825	COG0180	Tryptophanyl-tRNA synthetase
RD09_RS13845	COG3181	Tripartite tricarboxylate transporter family receptor
RD09_RS13855	COG0583	DNA-binding transcription factor activity
RD09_RS13860	COG1028	Short-chain dehydrogenase reductase Sdr
RD09_RS13865	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
RD09_RS13870	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RD09_RS13875	COG0508	dehydrogenase complex catalyzes the overall conversion of
RD09_RS13880	COG0567	Dehydrogenase, E1 component
RD09_RS13885	COG1297	OPT oligopeptide transporter protein
RD09_RS13890	COG1297	OPT oligopeptide transporter protein
RD09_RS13895	COG1522	sequence-specific DNA binding
RD09_RS13905	COG0280	phosphate acetyltransferase
RD09_RS13905	COG0281	malic enzyme
RD09_RS13910	COG3539	Fimbrial protein
RD09_RS13925	COG0613	PHP domain protein
RD09_RS13960	COG0084	hydrolase, TatD family'
RD09_RS13965	COG1136	(ABC) transporter
RD09_RS13980	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
RD09_RS13985	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
RD09_RS13990	COG1028	Short-chain dehydrogenase reductase Sdr
RD09_RS13995	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
RD09_RS14010	COG1022	Amp-dependent synthetase and ligase
RD09_RS14045	COG2205	protein histidine kinase activity
RD09_RS14050	COG0745	RESPONSE REGULATOR receiver
RD09_RS14055	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
RD09_RS14065	COG1295	ribonuclease BN
RD09_RS14080	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
RD09_RS14105	COG1534	Rna-binding protein
RD09_RS14110	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
RD09_RS14115	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
RD09_RS14125	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
RD09_RS14135	COG0248	Ppx GppA phosphatase
RD09_RS14160	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
RD09_RS14175	COG2732	(Barnase) inhibitor
RD09_RS14185	COG0281	malic enzyme
RD09_RS14185	COG0280	phosphate acetyltransferase
RD09_RS14195	COG0436	Aminotransferase
RD09_RS14200	COG0741	lytic transglycosylase activity
RD09_RS14205	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
RD09_RS14230	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
RD09_RS14230	COG1648	precorrin-2 dehydrogenase activity
RD09_RS14235	COG3468	outer membrane autotransporter barrel domain protein
RD09_RS14245	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
RD09_RS14250	COG2027	D-alanyl-D-alanine carboxypeptidase
RD09_RS14255	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
RD09_RS14260	COG0343	queuine tRNA-ribosyltransferase activity
RD09_RS14265	COG1862	Preprotein translocase
RD09_RS14270	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RD09_RS14275	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RD09_RS14290	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
RD09_RS14295	COG1702	phosphate starvation-inducible protein PhoH
RD09_RS14300	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
RD09_RS14305	COG4535	Mg2 and Co2 transporter CorC
RD09_RS14315	COG0667	Aldo Keto reductase
RD09_RS14340	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
RD09_RS14345	COG0745	RESPONSE REGULATOR receiver
RD09_RS14350	COG2201	protein-glutamate methylesterase activity
RD09_RS14360	COG0840	transmembrane signaling receptor activity
RD09_RS14375	COG0745	RESPONSE REGULATOR receiver
RD09_RS14410	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
RD09_RS14420	COG0739	heme binding
RD09_RS14430	COG0521	Mo-molybdopterin cofactor biosynthetic process
RD09_RS14440	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
RD09_RS14470	COG0625	glutathione transferase activity
RD09_RS14485	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
RD09_RS14490	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
RD09_RS14495	COG0126	phosphoglycerate kinase activity
RD09_RS14500	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
RD09_RS14505	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
RD09_RS14510	COG1385	rRNA (uridine-N3-)-methyltransferase activity
RD09_RS14525	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
RD09_RS14530	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RD09_RS14535	COG0508	dehydrogenase complex catalyzes the overall conversion of
RD09_RS14540	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
RD09_RS14550	COG4566	intracellular signal transduction
RD09_RS14555	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
RD09_RS14560	COG0339	signal peptide processing
RD09_RS14565	COG1999	signal sequence binding
RD09_RS14585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RD09_RS14595	COG1187	pseudouridine synthase activity
RD09_RS14600	COG3161	chorismate lyase activity
RD09_RS14605	COG2814	Major facilitator Superfamily
RD09_RS14615	COG0667	Aldo Keto reductase
RD09_RS14630	COG0335	large ribosomal subunit rRNA binding
RD09_RS14660	COG0175	sulfate reduction
RD09_RS14665	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
RD09_RS14670	COG4208	sulfate ABC transporter
RD09_RS14675	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
RD09_RS14690	COG0450	alkyl hydroperoxide reductase
RD09_RS14695	COG1960	acyl-CoA dehydrogenase activity
RD09_RS14710	COG0123	including yeast histone deacetylase and acetoin utilization protein
RD09_RS14715	COG2951	lytic endotransglycosylase activity
RD09_RS14730	COG1555	photosystem II stabilization
RD09_RS14730	COG1596	polysaccharide export
RD09_RS14735	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RD09_RS14740	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
RD09_RS14745	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
RD09_RS14765	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
RD09_RS14770	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
RD09_RS14775	COG0287	Prephenate dehydrogenase
RD09_RS14785	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
RD09_RS14800	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
RD09_RS14810	COG2814	Major facilitator Superfamily
RD09_RS14835	COG0583	DNA-binding transcription factor activity
RD09_RS14870	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
RD09_RS14885	COG0667	Aldo Keto reductase
RD09_RS14895	COG5265	(ABC) transporter
RD09_RS14940	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
RD09_RS14945	COG0439	Biotin carboxylase
RD09_RS14950	COG2188	Transcriptional regulator
RD09_RS14975	COG0511	ligase activity, forming carbon-carbon bonds
RD09_RS14985	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
RD09_RS15005	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
RD09_RS15020	COG0500	methyltransferase
RD09_RS15025	COG5265	(ABC) transporter
RD09_RS15040	COG0028	Belongs to the TPP enzyme family
RD09_RS15045	COG0440	acetolactate synthase activity
RD09_RS15050	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
RD09_RS15055	COG1183	phosphatidylcholine synthase activity
RD09_RS15065	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
RD09_RS15070	COG1185	polyribonucleotide nucleotidyltransferase activity
RD09_RS15085	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
RD09_RS15105	COG0149	triose-phosphate isomerase activity
RD09_RS15110	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
RD09_RS15120	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
RD09_RS15130	COG3799	methylaspartate ammonia-lyase activity
RD09_RS15170	COG0583	DNA-binding transcription factor activity
RD09_RS15175	COG0626	cystathionine gamma-synthase activity
RD09_RS15180	COG3608	succinylglutamate desuccinylase aspartoacylase
RD09_RS15200	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RD09_RS15220	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
RD09_RS15235	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RD09_RS15240	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RD09_RS15245	COG1733	regulation of RNA biosynthetic process
RD09_RS15255	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
RD09_RS15260	COG0583	DNA-binding transcription factor activity
RD09_RS15265	COG1597	lipid kinase activity
RD09_RS15275	COG0671	phosphoesterase, PA-phosphatase related
RD09_RS15300	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
RD09_RS15305	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RD09_RS15310	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RD09_RS15315	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RD09_RS15320	COG0649	NAD binding
RD09_RS15325	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
RD09_RS15335	COG1034	ATP synthesis coupled electron transport
RD09_RS15340	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
RD09_RS15345	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RD09_RS15355	COG0713	ATP synthesis coupled electron transport
RD09_RS15370	COG1007	ATP synthesis coupled electron transport
RD09_RS15380	COG4774	siderophore transport
RD09_RS15385	COG4774	siderophore transport
RD09_RS15400	COG0028	Belongs to the TPP enzyme family
RD09_RS15405	COG3181	Tripartite tricarboxylate transporter family receptor
RD09_RS15410	COG0583	DNA-binding transcription factor activity
RD09_RS15415	COG0560	Phosphoserine phosphatase
RD09_RS15420	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
RD09_RS15425	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
RD09_RS15430	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
RD09_RS15440	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
RD09_RS15445	COG0308	aminopeptidase N
RD09_RS15465	COG0028	Belongs to the TPP enzyme family
RD09_RS15485	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RD09_RS15495	COG0318	PFAM AMP-dependent synthetase and ligase
RD09_RS15505	COG1802	Transcriptional regulator
RD09_RS15515	COG1802	Transcriptional regulator
RD09_RS15525	COG1028	Short-chain dehydrogenase reductase Sdr
RD09_RS15545	COG1126	abc transporter atp-binding protein
RD09_RS15550	COG0765	amino acid transport
RD09_RS15570	COG1538	Outer membrane efflux protein
RD09_RS15575	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RD09_RS15580	COG2274	protein secretion by the type I secretion system
RD09_RS15585	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
RD09_RS15595	COG2994	toxin metabolic process
RD09_RS15610	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RD09_RS15615	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
RD09_RS15625	COG0583	DNA-binding transcription factor activity
RD09_RS15635	COG0142	geranyltranstransferase activity
RD09_RS15645	COG0261	This protein binds to 23S rRNA in the presence of protein L20
RD09_RS15650	COG0211	Belongs to the bacterial ribosomal protein bL27 family
RD09_RS15655	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
RD09_RS15660	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
RD09_RS15700	COG3712	iron ion homeostasis
RD09_RS15705	COG4774	siderophore transport
RD09_RS15710	COG2353	YceI-like domain
RD09_RS15730	COG0019	diaminopimelate decarboxylase activity
RD09_RS15750	COG0747	negative chemotaxis
RD09_RS15755	COG0601	transmembrane transport
RD09_RS15760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RD09_RS15770	COG0154	amidase activity
RD09_RS15775	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
RD09_RS15800	COG2154	pterin-4-alpha-carbinolamine dehydratase
RD09_RS15810	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
RD09_RS15820	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
RD09_RS15825	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
RD09_RS15830	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
RD09_RS15835	COG1929	Belongs to the glycerate kinase type-1 family
RD09_RS15840	COG0469	pyruvate kinase activity
RD09_RS15845	COG0700	Nucleoside recognition
RD09_RS15875	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
RD09_RS15880	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RD09_RS15895	COG0823	Involved in the tonB-independent uptake of proteins
RD09_RS15905	COG0848	biopolymer transport protein
RD09_RS15910	COG0811	peptide transport
RD09_RS15915	COG0824	Thioesterase
RD09_RS15920	COG0442	prolyl-tRNA aminoacylation
RD09_RS15925	COG0494	nUDIX hydrolase
RD09_RS15940	COG2135	peptidase activity
RD09_RS16005	COG1196	nuclear chromosome segregation
RD09_RS16145	COG1464	Belongs to the NlpA lipoprotein family
RD09_RS16175	COG4211	Belongs to the binding-protein-dependent transport system permease family
RD09_RS16185	COG0154	amidase activity
RD09_RS16190	COG0288	reversible hydration of carbon dioxide
RD09_RS16205	COG0514	ATP-dependent DNA helicase (RecQ)
RD09_RS16210	COG2255	four-way junction helicase activity
RD09_RS16225	COG0632	four-way junction helicase activity
RD09_RS16230	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
RD09_RS16250	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RD09_RS16260	COG0006	proline dipeptidase activity
RD09_RS16285	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
RD09_RS16300	COG4783	chaperone-mediated protein folding
RD09_RS16305	COG0429	hydrolase of the alpha beta-hydrolase fold
RD09_RS16335	COG0513	Belongs to the DEAD box helicase family
RD09_RS16355	COG1058	Belongs to the CinA family
RD09_RS16355	COG1546	Belongs to the CinA family
RD09_RS16360	COG1414	Transcriptional regulator
RD09_RS16380	COG0167	dihydroorotate dehydrogenase activity
RD09_RS16385	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
RD09_RS16395	COG0583	DNA-binding transcription factor activity
RD09_RS16455	COG0281	malic enzyme
RD09_RS16455	COG0280	phosphate acetyltransferase
RD09_RS16465	COG0601	transmembrane transport
RD09_RS16470	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RD09_RS16475	COG4172	Belongs to the ABC transporter superfamily
RD09_RS16505	COG0640	Transcriptional regulator
RD09_RS16520	COG3135	benzoate transporter
RD09_RS16525	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
RD09_RS16530	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
RD09_RS16535	COG0742	ribosomal rna small subunit methyltransferase
RD09_RS16555	COG3639	organic phosphonate transmembrane transporter activity
RD09_RS16560	COG3639	organic phosphonate transmembrane transporter activity
RD09_RS16565	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
RD09_RS16600	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
RD09_RS16605	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
RD09_RS16615	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
RD09_RS16620	COG1546	Belongs to the CinA family
RD09_RS16620	COG1058	Belongs to the CinA family
RD09_RS16625	COG0284	orotidine-5'-phosphate decarboxylase activity
RD09_RS16630	COG1252	NADH dehydrogenase
RD09_RS16645	COG3468	outer membrane autotransporter barrel domain protein
RD09_RS16650	COG0459	protein refolding
RD09_RS16655	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
RD09_RS16675	COG1053	succinate dehydrogenase
RD09_RS16685	COG0583	DNA-binding transcription factor activity
RD09_RS16690	COG1053	succinate dehydrogenase
RD09_RS16710	COG3706	GGDEF domain
RD09_RS16745	COG1262	PFAM Formylglycine-generating sulfatase enzyme
RD09_RS16750	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
RD09_RS16760	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RD09_RS16770	COG0069	glutamate synthase activity
RD09_RS16775	COG2391	methyltransferase activity
RD09_RS16780	COG0679	Auxin Efflux Carrier
RD09_RS16805	COG0557	exoribonuclease II activity
RD09_RS16810	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RD09_RS16820	COG3128	pkhd-type hydroxylase
RD09_RS16825	COG0776	regulation of translation
RD09_RS16855	COG0642	Histidine kinase
RD09_RS16860	COG3158	transport of potassium into the cell
RD09_RS16865	COG0137	argininosuccinate synthase activity
RD09_RS16870	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
RD09_RS16875	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
RD09_RS16885	COG0583	DNA-binding transcription factor activity
RD09_RS16895	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
RD09_RS16915	COG2186	Transcriptional regulator
RD09_RS16925	COG2223	nitrite transmembrane transporter activity
RD09_RS16935	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RD09_RS16940	COG0450	alkyl hydroperoxide reductase
RD09_RS16960	COG1214	PFAM Peptidase M22, glycoprotease
RD09_RS16965	COG1573	uracil-dna glycosylase
RD09_RS16970	COG0477	Major facilitator Superfamily
RD09_RS16975	COG1196	nuclear chromosome segregation
RD09_RS16985	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
RD09_RS16990	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
RD09_RS17005	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
RD09_RS17010	COG1122	ATPase activity
RD09_RS17015	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
RD09_RS17020	COG1268	BioY protein
RD09_RS17040	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
RD09_RS17075	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
RD09_RS17080	COG2878	Part of a membrane complex involved in electron transport
RD09_RS17095	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
RD09_RS17100	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
RD09_RS17105	COG0251	oxidation-reduction process
RD09_RS17115	COG3228	Belongs to the MtfA family
RD09_RS17120	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
RD09_RS17130	COG0133	tryptophan synthase activity
RD09_RS17135	COG0159	tryptophan synthase activity
RD09_RS17140	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
RD09_RS17145	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
RD09_RS17160	COG1530	ribonuclease E activity
RD09_RS17170	COG0546	phosphoglycolate phosphatase activity
RD09_RS17175	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
RD09_RS17180	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
RD09_RS17190	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD09_RS17195	COG0583	DNA-binding transcription factor activity
RD09_RS17205	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD09_RS17230	COG0251	oxidation-reduction process
RD09_RS17235	COG1017	nitric oxide dioxygenase activity
RD09_RS17235	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
RD09_RS17240	COG2031	fatty acid transporter
RD09_RS17245	COG1012	belongs to the aldehyde dehydrogenase family
RD09_RS17250	COG1802	Transcriptional regulator
RD09_RS17260	COG1278	Cold shock
RD09_RS17265	COG0583	DNA-binding transcription factor activity
RD09_RS17285	COG0183	Belongs to the thiolase family
RD09_RS17295	COG1960	acyl-CoA dehydrogenase activity
RD09_RS17300	COG0583	DNA-binding transcription factor activity
RD09_RS17305	COG3181	Tripartite tricarboxylate transporter family receptor
RD09_RS17310	COG1024	Enoyl-CoA hydratase
RD09_RS17315	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD09_RS17320	COG1253	flavin adenine dinucleotide binding
RD09_RS17325	COG1285	pathogenesis
RD09_RS17335	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RD09_RS17350	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
RD09_RS17360	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RD09_RS17365	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
RD09_RS17380	COG2031	fatty acid transporter
RD09_RS17390	COG0786	glutamate:sodium symporter activity
RD09_RS17405	COG0463	Glycosyl transferase, family 2
RD09_RS17410	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
RD09_RS17435	COG0697	spore germination
RD09_RS17445	COG3181	Tripartite tricarboxylate transporter family receptor
RD09_RS17470	COG0028	Belongs to the TPP enzyme family
RD09_RS17475	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD09_RS17480	COG1024	Enoyl-CoA hydratase
RD09_RS17480	COG1250	3-hydroxyacyl-CoA dehydrogenase
RD09_RS17485	COG3181	Tripartite tricarboxylate transporter family receptor
RD09_RS17495	COG0492	ferredoxin-NADP+ reductase activity
RD09_RS17520	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD09_RS17530	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD09_RS17550	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
RD09_RS17565	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
RD09_RS17570	COG2823	Periplasmic or secreted lipoprotein
RD09_RS17585	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
RD09_RS17595	COG1309	transcriptional regulator
RD09_RS17600	COG0471	metal ion transport
RD09_RS17605	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
RD09_RS17610	COG0772	Belongs to the SEDS family
RD09_RS17615	COG0768	penicillin binding
RD09_RS17625	COG1792	Involved in formation and maintenance of cell shape
RD09_RS17630	COG1077	Cell shape determining protein MreB Mrl
RD09_RS17635	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
RD09_RS17640	COG0154	amidase activity
RD09_RS17645	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
RD09_RS17650	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
RD09_RS17655	COG0708	Exodeoxyribonuclease III
RD09_RS17660	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
RD09_RS17665	COG2860	membrane
RD09_RS17700	COG1012	belongs to the aldehyde dehydrogenase family
RD09_RS17710	COG3069	C4-dicarboxylate transmembrane transporter activity
RD09_RS17720	COG1802	Transcriptional regulator
RD09_RS17755	COG1595	DNA-templated transcription, initiation
RD09_RS17760	COG3712	iron ion homeostasis
RD09_RS17770	COG3720	iron ion transport
RD09_RS17775	COG4558	Periplasmic binding protein
RD09_RS17780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RD09_RS17785	COG1120	ATPase activity
RD09_RS17790	COG1683	Conserved Protein
RD09_RS17840	COG1234	tRNA 3'-trailer cleavage
RD09_RS17875	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
RD09_RS17885	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
RD09_RS17900	COG0540	Belongs to the ATCase OTCase family
RD09_RS17905	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
RD09_RS17910	COG1678	Uncharacterized ACR, COG1678
RD09_RS17925	COG0352	thiamine-phosphate diphosphorylase activity
RD09_RS17930	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
RD09_RS17955	COG1960	acyl-CoA dehydrogenase activity
RD09_RS17960	COG1024	Enoyl-CoA hydratase
RD09_RS18030	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
RD09_RS18040	COG0583	DNA-binding transcription factor activity
RD09_RS18045	COG2814	Major facilitator Superfamily
RD09_RS18050	COG0129	dihydroxy-acid dehydratase activity
RD09_RS18055	COG2207	Transcriptional regulator
RD09_RS18060	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RD09_RS18070	COG0657	acetylesterase activity
RD09_RS18075	COG0747	negative chemotaxis
RD09_RS18080	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RD09_RS18085	COG2808	Putative FMN-binding domain
RD09_RS18100	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
RD09_RS18105	COG1970	mechanosensitive ion channel activity
RD09_RS18110	COG0723	plastoquinol--plastocyanin reductase activity
RD09_RS18115	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
RD09_RS18120	COG2857	Cytochrome c1
RD09_RS18125	COG0625	glutathione transferase activity
RD09_RS18130	COG2969	positive regulation of protein catabolic process
RD09_RS18155	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
RD09_RS18170	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
RD09_RS18175	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
RD09_RS18180	COG4988	ABC transporter
RD09_RS18190	COG1294	oxidase, subunit
RD09_RS18215	COG1960	acyl-CoA dehydrogenase activity
RD09_RS18225	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD09_RS18230	COG0405	Gamma-glutamyltransferase
RD09_RS18240	COG3181	Tripartite tricarboxylate transporter family receptor
RD09_RS18250	COG0114	fumarate hydratase activity
RD09_RS18255	COG0802	atpase or kinase
RD09_RS18260	COG0860	N-Acetylmuramoyl-L-alanine amidase
RD09_RS18265	COG0586	Pfam SNARE associated Golgi protein
RD09_RS18270	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
RD09_RS18275	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
RD09_RS18280	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
RD09_RS18295	COG0617	tRNA 3'-terminal CCA addition
RD09_RS18320	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
RD09_RS18325	COG2188	Transcriptional regulator
RD09_RS18335	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RD09_RS18345	COG1028	Short-chain dehydrogenase reductase Sdr
RD09_RS18370	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RD09_RS18375	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
RD09_RS18380	COG1012	belongs to the aldehyde dehydrogenase family
RD09_RS18400	COG4257	antibiotic catabolic process
RD09_RS18410	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
RD09_RS18415	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
RD09_RS18425	COG1250	3-hydroxyacyl-CoA dehydrogenase
RD09_RS18430	COG2031	fatty acid transporter
RD09_RS18435	COG1028	Short-chain dehydrogenase reductase Sdr
RD09_RS18440	COG1414	Transcriptional regulator
RD09_RS18450	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
RD09_RS18465	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
RD09_RS18505	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
RD09_RS18505	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
RD09_RS18510	COG0509	glycine decarboxylation via glycine cleavage system
RD09_RS18515	COG0404	The glycine cleavage system catalyzes the degradation of glycine
RD09_RS18525	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
RD09_RS18535	COG2081	HI0933 family
RD09_RS18565	COG0717	Belongs to the dCTP deaminase family
RD09_RS18580	COG0489	protein tyrosine kinase activity
RD09_RS18590	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RD09_RS18590	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RD09_RS18595	COG1054	Belongs to the UPF0176 family
RD09_RS18630	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
RD09_RS18635	COG1280	lysine exporter protein (LysE YggA)
RD09_RS18640	COG0513	Belongs to the DEAD box helicase family
RD09_RS18650	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
RD09_RS18670	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
RD09_RS18685	COG2226	methyltransferase
RD09_RS18690	COG0745	RESPONSE REGULATOR receiver
RD09_RS18695	COG5002	protein histidine kinase activity
RD09_RS18705	COG5002	protein histidine kinase activity
RD09_RS18715	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RD09_RS18720	COG0583	DNA-binding transcription factor activity
RD09_RS18730	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
RD09_RS18735	COG1984	allophanate hydrolase subunit 2
RD09_RS18750	COG3181	Tripartite tricarboxylate transporter family receptor
RD09_RS18765	COG1024	Enoyl-CoA hydratase
RD09_RS18780	COG1802	Transcriptional regulator
RD09_RS18795	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
RD09_RS18800	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
RD09_RS18815	COG0583	DNA-binding transcription factor activity
RD09_RS18825	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
RD09_RS18835	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RD09_RS18840	COG0154	amidase activity
RD09_RS18850	COG1609	Transcriptional regulator
RD09_RS18870	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
RD09_RS18890	COG2814	Major facilitator Superfamily
RD09_RS18895	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
RD09_RS18915	COG1999	signal sequence binding
RD09_RS18920	COG0109	protoheme IX farnesyltransferase activity
RD09_RS18960	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
RD09_RS18980	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
RD09_RS18985	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
RD09_RS18995	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
RD09_RS19000	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
RD09_RS19010	COG0069	glutamate synthase activity
RD09_RS19010	COG0070	glutamate synthase
RD09_RS19010	COG0067	glutamate synthase
RD09_RS19020	COG3047	cAMP biosynthetic process
RD09_RS19030	COG1127	ABC transporter
RD09_RS19035	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
RD09_RS19040	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
RD09_RS19045	COG2853	Lipoprotein
RD09_RS19055	COG1131	(ABC) transporter
RD09_RS19060	COG0842	Transport permease protein
RD09_RS19070	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
RD09_RS19075	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
RD09_RS19080	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
RD09_RS19085	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
RD09_RS19090	COG0131	Imidazoleglycerol-phosphate dehydratase
RD09_RS19095	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
RD09_RS19100	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
RD09_RS19105	COG0107	imidazoleglycerol-phosphate synthase activity
RD09_RS19110	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
RD09_RS19115	COG0140	phosphoribosyl-ATP diphosphatase activity
RD09_RS19120	COG0537	adenosine 5'-monophosphoramidase activity
RD09_RS19125	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
RD09_RS19130	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
RD09_RS19145	COG3181	Tripartite tricarboxylate transporter family receptor
RD09_RS19180	COG3702	type iv secretory pathway
RD09_RS19185	COG3451	type IV secretory pathway VirB4
RD09_RS19200	COG3736	Type IV secretory pathway, component VirB8
RD09_RS19205	COG3504	Conjugal transfer protein
RD09_RS19210	COG2948	multi-organism process
RD09_RS19215	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
RD09_RS19225	COG0697	spore germination
RD09_RS19245	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
RD09_RS19250	COG0747	negative chemotaxis
RD09_RS19255	COG0601	transmembrane transport
RD09_RS19260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RD09_RS19265	COG0444	Belongs to the ABC transporter superfamily
RD09_RS19275	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
RD09_RS19285	COG0494	nUDIX hydrolase
RD09_RS19325	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
RD09_RS19330	COG0237	dephospho-CoA kinase activity
RD09_RS19335	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
RD09_RS19350	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
RD09_RS19355	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
RD09_RS19365	COG0477	Major facilitator Superfamily
RD09_RS19370	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
RD09_RS19385	COG1126	abc transporter atp-binding protein
RD09_RS19390	COG0765	amino acid transport
RD09_RS19395	COG4597	amino acid ABC transporter
RD09_RS19400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RD09_RS19405	COG2884	Cell division ATP-binding protein ftsE
RD09_RS19410	COG2177	Part of the ABC transporter FtsEX involved in
RD09_RS19415	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
RD09_RS19425	COG1194	a g-specific adenine glycosylase
RD09_RS19435	COG2226	methyltransferase
RD09_RS19445	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD09_RS19450	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD09_RS19465	COG1024	Enoyl-CoA hydratase
RD09_RS19485	COG1024	Enoyl-CoA hydratase
RD09_RS19490	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RD09_RS19495	COG3181	Tripartite tricarboxylate transporter family receptor
RD09_RS19505	COG0753	catalase activity
RD09_RS19510	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RD09_RS19515	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
RD09_RS19525	COG2175	clavaminate synthase activity
RD09_RS19530	COG1473	amidohydrolase
RD09_RS19535	COG4608	Belongs to the ABC transporter superfamily
RD09_RS19540	COG0444	Belongs to the ABC transporter superfamily
RD09_RS19555	COG0747	negative chemotaxis
RD09_RS19560	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
RD09_RS19595	COG0436	Aminotransferase
RD09_RS19600	COG1278	Cold shock