locus-tag	class	description
CXD87_RS00005	COG0445	tRNA wobble uridine modification
CXD87_RS00010	COG0357	Ribosomal RNA small subunit methyltransferase G
CXD87_RS00015	COG1192	Involved in chromosome partitioning
CXD87_RS00025	COG1475	DNA binding
CXD87_RS00050	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CXD87_RS00060	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CXD87_RS00070	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CXD87_RS00075	COG0081	regulation of translation
CXD87_RS00080	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CXD87_RS00085	COG0222	ribosome binding
CXD87_RS00090	COG0085	RNA polymerase activity
CXD87_RS00095	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CXD87_RS00135	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CXD87_RS00160	COG1024	Enoyl-CoA hydratase
CXD87_RS00180	COG0752	glycyl-tRNA synthetase alpha subunit
CXD87_RS00185	COG0751	glycine-tRNA ligase activity
CXD87_RS00190	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CXD87_RS00195	COG0204	Acyl-transferase
CXD87_RS00210	COG0242	peptide deformylase activity
CXD87_RS00250	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CXD87_RS00255	COG2813	Specifically methylates the guanine in position
CXD87_RS00255	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CXD87_RS00270	COG2223	nitrite transmembrane transporter activity
CXD87_RS00280	COG1794	racemase activity, acting on amino acids and derivatives
CXD87_RS00285	COG1126	abc transporter atp-binding protein
CXD87_RS00290	COG0765	amino acid transport
CXD87_RS00295	COG0765	amino acid transport
CXD87_RS00300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXD87_RS00365	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CXD87_RS00395	COG0326	Molecular chaperone. Has ATPase activity
CXD87_RS00400	COG0625	glutathione transferase activity
CXD87_RS00415	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CXD87_RS00420	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CXD87_RS00450	COG0438	transferase activity, transferring glycosyl groups
CXD87_RS00455	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CXD87_RS00460	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CXD87_RS00490	COG0859	PFAM glycosyl transferase family 9
CXD87_RS00505	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CXD87_RS00515	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CXD87_RS00520	COG1127	ABC transporter
CXD87_RS00540	COG1686	Belongs to the peptidase S11 family
CXD87_RS00550	COG2921	Belongs to the UPF0250 family
CXD87_RS00555	COG0321	lipoyl(octanoyl) transferase activity
CXD87_RS00560	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CXD87_RS00595	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CXD87_RS00605	COG0018	arginyl-trna synthetase
CXD87_RS00625	COG0395	ABC-type sugar transport system, permease component
CXD87_RS00630	COG1175	transmembrane transport
CXD87_RS00635	COG1653	transport
CXD87_RS00640	COG3842	ATPase activity
CXD87_RS00645	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CXD87_RS00655	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CXD87_RS00675	COG1609	Transcriptional regulator
CXD87_RS00685	COG0154	amidase activity
CXD87_RS00690	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CXD87_RS00700	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CXD87_RS00710	COG0583	DNA-binding transcription factor activity
CXD87_RS00730	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CXD87_RS00745	COG1802	Transcriptional regulator
CXD87_RS00760	COG1024	Enoyl-CoA hydratase
CXD87_RS00770	COG3181	Tripartite tricarboxylate transporter family receptor
CXD87_RS00785	COG1984	allophanate hydrolase subunit 2
CXD87_RS00790	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CXD87_RS00800	COG0583	DNA-binding transcription factor activity
CXD87_RS00805	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CXD87_RS00815	COG5002	protein histidine kinase activity
CXD87_RS00825	COG5002	protein histidine kinase activity
CXD87_RS00830	COG0745	RESPONSE REGULATOR receiver
CXD87_RS00835	COG2226	methyltransferase
CXD87_RS00850	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CXD87_RS00870	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CXD87_RS00880	COG0513	Belongs to the DEAD box helicase family
CXD87_RS00885	COG1280	lysine exporter protein (LysE YggA)
CXD87_RS00890	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CXD87_RS00930	COG1054	Belongs to the UPF0176 family
CXD87_RS00935	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CXD87_RS00935	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CXD87_RS00945	COG0489	protein tyrosine kinase activity
CXD87_RS00960	COG0717	Belongs to the dCTP deaminase family
CXD87_RS00990	COG2081	HI0933 family
CXD87_RS01000	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CXD87_RS01010	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CXD87_RS01015	COG0509	glycine decarboxylation via glycine cleavage system
CXD87_RS01020	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CXD87_RS01020	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CXD87_RS01060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CXD87_RS01075	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CXD87_RS01085	COG1414	Transcriptional regulator
CXD87_RS01090	COG1028	Short-chain dehydrogenase reductase Sdr
CXD87_RS01095	COG2031	fatty acid transporter
CXD87_RS01100	COG1250	3-hydroxyacyl-CoA dehydrogenase
CXD87_RS01110	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CXD87_RS01115	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CXD87_RS01125	COG4257	antibiotic catabolic process
CXD87_RS01150	COG1012	belongs to the aldehyde dehydrogenase family
CXD87_RS01155	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CXD87_RS01160	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CXD87_RS01185	COG1028	Short-chain dehydrogenase reductase Sdr
CXD87_RS01195	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CXD87_RS01205	COG2188	Transcriptional regulator
CXD87_RS01210	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CXD87_RS01235	COG0617	tRNA 3'-terminal CCA addition
CXD87_RS01250	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CXD87_RS01255	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CXD87_RS01260	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CXD87_RS01265	COG0586	Pfam SNARE associated Golgi protein
CXD87_RS01270	COG0860	N-Acetylmuramoyl-L-alanine amidase
CXD87_RS01275	COG0802	atpase or kinase
CXD87_RS01280	COG0114	fumarate hydratase activity
CXD87_RS01290	COG3181	Tripartite tricarboxylate transporter family receptor
CXD87_RS01300	COG0405	Gamma-glutamyltransferase
CXD87_RS01305	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CXD87_RS01340	COG1294	oxidase, subunit
CXD87_RS01350	COG4988	ABC transporter
CXD87_RS01355	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CXD87_RS01405	COG2969	positive regulation of protein catabolic process
CXD87_RS01410	COG0625	glutathione transferase activity
CXD87_RS01415	COG2857	Cytochrome c1
CXD87_RS01420	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CXD87_RS01425	COG0723	plastoquinol--plastocyanin reductase activity
CXD87_RS01430	COG1970	mechanosensitive ion channel activity
CXD87_RS01435	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CXD87_RS01450	COG2808	Putative FMN-binding domain
CXD87_RS01455	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CXD87_RS01460	COG0747	negative chemotaxis
CXD87_RS01465	COG0657	acetylesterase activity
CXD87_RS01475	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CXD87_RS01480	COG2207	Transcriptional regulator
CXD87_RS01485	COG0129	dihydroxy-acid dehydratase activity
CXD87_RS01490	COG2814	Major facilitator Superfamily
CXD87_RS01495	COG0583	DNA-binding transcription factor activity
CXD87_RS01505	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
CXD87_RS01575	COG1024	Enoyl-CoA hydratase
CXD87_RS01580	COG1960	acyl-CoA dehydrogenase activity
CXD87_RS01605	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CXD87_RS01610	COG0352	thiamine-phosphate diphosphorylase activity
CXD87_RS01625	COG1678	Uncharacterized ACR, COG1678
CXD87_RS01630	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CXD87_RS01635	COG0540	Belongs to the ATCase OTCase family
CXD87_RS01650	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CXD87_RS01660	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CXD87_RS01695	COG1234	tRNA 3'-trailer cleavage
CXD87_RS01715	COG3064	Membrane
CXD87_RS01745	COG1683	Conserved Protein
CXD87_RS01750	COG1120	ATPase activity
CXD87_RS01755	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CXD87_RS01760	COG4558	Periplasmic binding protein
CXD87_RS01765	COG3720	iron ion transport
CXD87_RS01775	COG3712	iron ion homeostasis
CXD87_RS01780	COG1595	DNA-templated transcription, initiation
CXD87_RS01815	COG1802	Transcriptional regulator
CXD87_RS01825	COG3069	C4-dicarboxylate transmembrane transporter activity
CXD87_RS01835	COG1012	belongs to the aldehyde dehydrogenase family
CXD87_RS01870	COG2860	membrane
CXD87_RS01875	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CXD87_RS01880	COG0708	Exodeoxyribonuclease III
CXD87_RS01885	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CXD87_RS01890	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CXD87_RS01895	COG0154	amidase activity
CXD87_RS01900	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CXD87_RS01905	COG1077	Cell shape determining protein MreB Mrl
CXD87_RS01910	COG1792	Involved in formation and maintenance of cell shape
CXD87_RS01920	COG0768	penicillin binding
CXD87_RS01925	COG0772	Belongs to the SEDS family
CXD87_RS01930	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CXD87_RS01935	COG0471	metal ion transport
CXD87_RS01940	COG1309	transcriptional regulator
CXD87_RS01950	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CXD87_RS01965	COG2823	Periplasmic or secreted lipoprotein
CXD87_RS01970	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CXD87_RS01985	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CXD87_RS02005	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CXD87_RS02015	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CXD87_RS02035	COG0492	ferredoxin-NADP+ reductase activity
CXD87_RS02045	COG3181	Tripartite tricarboxylate transporter family receptor
CXD87_RS02050	COG1250	3-hydroxyacyl-CoA dehydrogenase
CXD87_RS02050	COG1024	Enoyl-CoA hydratase
CXD87_RS02055	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CXD87_RS02060	COG0028	Belongs to the TPP enzyme family
CXD87_RS02085	COG3181	Tripartite tricarboxylate transporter family receptor
CXD87_RS02100	COG0697	spore germination
CXD87_RS02130	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CXD87_RS02135	COG0463	Glycosyl transferase, family 2
CXD87_RS02150	COG0786	glutamate:sodium symporter activity
CXD87_RS02160	COG2031	fatty acid transporter
CXD87_RS02175	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CXD87_RS02205	COG3181	Tripartite tricarboxylate transporter family receptor
CXD87_RS02215	COG0277	FAD linked oxidase domain protein
CXD87_RS02220	COG1960	acyl-CoA dehydrogenase activity
CXD87_RS02225	COG1960	acyl-CoA dehydrogenase activity
CXD87_RS02235	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CXD87_RS02250	COG2072	flavoprotein involved in K transport
CXD87_RS02255	COG0604	alcohol dehydrogenase
CXD87_RS02270	COG1024	Enoyl-CoA hydratase
CXD87_RS02290	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CXD87_RS02295	COG1522	sequence-specific DNA binding
CXD87_RS02300	COG0183	Belongs to the thiolase family
CXD87_RS02310	COG1960	acyl-CoA dehydrogenase activity
CXD87_RS02355	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CXD87_RS02360	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CXD87_RS02365	COG2890	protein-(glutamine-N5) methyltransferase activity
CXD87_RS02370	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CXD87_RS02380	COG3181	Tripartite tricarboxylate transporter family receptor
CXD87_RS02415	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CXD87_RS02420	COG1660	Displays ATPase and GTPase activities
CXD87_RS02430	COG2010	Cytochrome c
CXD87_RS02430	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CXD87_RS02435	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CXD87_RS02450	COG1137	ATPase activity
CXD87_RS02465	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CXD87_RS02475	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CXD87_RS02510	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CXD87_RS02515	COG3568	Endonuclease Exonuclease Phosphatase
CXD87_RS02520	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CXD87_RS02550	COG0154	amidase activity
CXD87_RS02560	COG1414	Transcriptional regulator
CXD87_RS02570	COG1250	3-hydroxyacyl-CoA dehydrogenase
CXD87_RS02570	COG1024	Enoyl-CoA hydratase
CXD87_RS02580	COG2132	Multicopper oxidase
CXD87_RS02635	COG1024	Enoyl-CoA hydratase
CXD87_RS02640	COG1024	Enoyl-CoA hydratase
CXD87_RS02645	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CXD87_RS02665	COG0601	transmembrane transport
CXD87_RS02670	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CXD87_RS02675	COG4172	Belongs to the ABC transporter superfamily
CXD87_RS02685	COG2195	Cleaves the N-terminal amino acid of tripeptides
CXD87_RS02695	COG0210	DNA helicase
CXD87_RS02700	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CXD87_RS02705	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CXD87_RS02715	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CXD87_RS02720	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CXD87_RS02725	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CXD87_RS02730	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CXD87_RS02735	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CXD87_RS02740	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CXD87_RS02750	COG0356	it plays a direct role in the translocation of protons across the membrane
CXD87_RS02775	COG1024	Enoyl-CoA hydratase
CXD87_RS02780	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CXD87_RS02785	COG3634	alkyl hydroperoxide reductase activity
CXD87_RS02795	COG0037	tRNA processing
CXD87_RS02805	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CXD87_RS02810	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CXD87_RS02815	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CXD87_RS02820	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CXD87_RS02825	COG2967	ApaG domain
CXD87_RS02830	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CXD87_RS02835	COG0546	phosphoglycolate phosphatase activity
CXD87_RS02845	COG0512	Glutamine amidotransferase of anthranilate synthase
CXD87_RS02850	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CXD87_RS02855	COG0134	indole-3-glycerol-phosphate synthase activity
CXD87_RS02880	COG0583	DNA-binding transcription factor activity
CXD87_RS02895	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CXD87_RS02900	COG0259	pyridoxamine-phosphate oxidase activity
CXD87_RS02910	COG2814	Major facilitator Superfamily
CXD87_RS02915	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CXD87_RS02920	COG2188	Transcriptional regulator
CXD87_RS02925	COG0318	PFAM AMP-dependent synthetase and ligase
CXD87_RS02945	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CXD87_RS02955	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CXD87_RS02970	COG1215	transferase activity, transferring glycosyl groups
CXD87_RS02980	COG0601	transmembrane transport
CXD87_RS03015	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CXD87_RS03020	COG2894	cell division
CXD87_RS03025	COG0850	regulation of cytokinetic process
CXD87_RS03030	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CXD87_RS03035	COG1271	oxidase subunit
CXD87_RS03070	COG2979	Protein of unknown function (DUF533)
CXD87_RS03090	COG0741	lytic transglycosylase activity
CXD87_RS03090	COG1388	LysM domain
CXD87_RS03095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CXD87_RS03100	COG2226	methyltransferase
CXD87_RS03105	COG0328	RNA-DNA hybrid ribonuclease activity
CXD87_RS03155	COG2030	dehydratase
CXD87_RS03205	COG1960	acyl-CoA dehydrogenase activity
CXD87_RS03220	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CXD87_RS03240	COG2718	Belongs to the UPF0229 family
CXD87_RS03245	COG2719	SpoVR family
CXD87_RS03270	COG2188	Transcriptional regulator
CXD87_RS03300	COG0829	nickel cation binding
CXD87_RS03305	COG0831	urea catabolic process
CXD87_RS03315	COG0832	Belongs to the urease beta subunit family
CXD87_RS03320	COG0804	urea catabolic process
CXD87_RS03330	COG0830	nickel cation binding
CXD87_RS03335	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CXD87_RS03355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CXD87_RS03360	COG0601	transmembrane transport
CXD87_RS03365	COG0747	negative chemotaxis
CXD87_RS03375	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CXD87_RS03380	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CXD87_RS03390	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CXD87_RS03400	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
CXD87_RS03405	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CXD87_RS03410	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CXD87_RS03425	COG0438	transferase activity, transferring glycosyl groups
CXD87_RS03440	COG0438	transferase activity, transferring glycosyl groups
CXD87_RS03445	COG0438	transferase activity, transferring glycosyl groups
CXD87_RS03450	COG0166	Belongs to the GPI family
CXD87_RS03465	COG0277	FAD linked oxidase domain protein
CXD87_RS03470	COG0745	RESPONSE REGULATOR receiver
CXD87_RS03475	COG0642	Histidine kinase
CXD87_RS03480	COG1368	sulfuric ester hydrolase activity
CXD87_RS03490	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CXD87_RS03515	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CXD87_RS03525	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CXD87_RS03530	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CXD87_RS03540	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CXD87_RS03545	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CXD87_RS03550	COG0193	aminoacyl-tRNA hydrolase activity
CXD87_RS03560	COG0012	GTP binding
CXD87_RS03565	COG0582	viral genome integration into host DNA
CXD87_RS03590	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CXD87_RS03655	COG0745	RESPONSE REGULATOR receiver
CXD87_RS03670	COG1309	transcriptional regulator
CXD87_RS03700	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CXD87_RS03710	COG0405	Gamma-glutamyltransferase
CXD87_RS03785	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CXD87_RS03790	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CXD87_RS03800	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CXD87_RS03805	COG0513	Belongs to the DEAD box helicase family
CXD87_RS03815	COG0617	tRNA 3'-terminal CCA addition
CXD87_RS03830	COG0477	Major facilitator Superfamily
CXD87_RS03840	COG0583	DNA-binding transcription factor activity
CXD87_RS03855	COG1950	PFAM Membrane protein of
CXD87_RS03860	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CXD87_RS03875	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CXD87_RS03885	COG1560	Kdo2-lipid A biosynthetic process
CXD87_RS03890	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CXD87_RS03900	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CXD87_RS03910	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CXD87_RS03920	COG0803	Belongs to the bacterial solute-binding protein 9 family
CXD87_RS03935	COG0735	belongs to the Fur family
CXD87_RS03940	COG0523	cobalamin synthesis protein
CXD87_RS03950	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CXD87_RS03955	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CXD87_RS03970	COG2096	Adenosyltransferase
CXD87_RS03990	COG2084	Dehydrogenase
CXD87_RS04040	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CXD87_RS04045	COG0129	dihydroxy-acid dehydratase activity
CXD87_RS04050	COG4654	Cytochrome c, class I
CXD87_RS04055	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CXD87_RS04105	COG1473	amidohydrolase
CXD87_RS04110	COG0418	dihydroorotase activity
CXD87_RS04115	COG0488	(ABC) transporter
CXD87_RS04125	COG2001	Belongs to the MraZ family
CXD87_RS04130	COG0275	rRNA processing
CXD87_RS04135	COG3116	cell division
CXD87_RS04145	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CXD87_RS04150	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CXD87_RS04155	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CXD87_RS04165	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CXD87_RS04170	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CXD87_RS04175	COG1181	Belongs to the D-alanine--D-alanine ligase family
CXD87_RS04180	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CXD87_RS04190	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CXD87_RS04195	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CXD87_RS04205	COG0739	heme binding
CXD87_RS04210	COG0653	protein targeting
CXD87_RS04230	COG1028	Short-chain dehydrogenase reductase Sdr
CXD87_RS04235	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CXD87_RS04240	COG1522	sequence-specific DNA binding
CXD87_RS04260	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CXD87_RS04270	COG0557	exoribonuclease II activity
CXD87_RS04275	COG3150	esterase
CXD87_RS04280	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CXD87_RS04285	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CXD87_RS04290	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CXD87_RS04295	COG0511	ligase activity, forming carbon-carbon bonds
CXD87_RS04300	COG0439	Biotin carboxylase
CXD87_RS04315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CXD87_RS04340	COG1696	Membrane protein involved in D-alanine export
CXD87_RS04345	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CXD87_RS04380	COG1522	sequence-specific DNA binding
CXD87_RS04395	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CXD87_RS04400	COG0045	succinate-CoA ligase (ADP-forming) activity
CXD87_RS04400	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CXD87_RS04400	COG1042	CoA-binding domain protein
CXD87_RS04415	COG1802	Transcriptional regulator
CXD87_RS04420	COG3069	C4-dicarboxylate transmembrane transporter activity
CXD87_RS04425	COG0513	Belongs to the DEAD box helicase family
CXD87_RS04430	COG0346	lactoylglutathione lyase activity
CXD87_RS04435	COG1335	isochorismatase
CXD87_RS04440	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CXD87_RS04445	COG1116	anion transmembrane transporter activity
CXD87_RS04460	COG3028	Belongs to the UPF0307 family
CXD87_RS04465	COG0312	modulator of DNA gyrase
CXD87_RS04470	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CXD87_RS04475	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CXD87_RS04480	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CXD87_RS04485	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CXD87_RS04495	COG0316	Belongs to the HesB IscA family
CXD87_RS04500	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CXD87_RS04515	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CXD87_RS04525	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CXD87_RS04530	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CXD87_RS04545	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CXD87_RS04545	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CXD87_RS04580	COG0583	DNA-binding transcription factor activity
CXD87_RS04585	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CXD87_RS04620	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CXD87_RS04630	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CXD87_RS04635	COG1845	cytochrome c oxidase, subunit III
CXD87_RS04640	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CXD87_RS04645	COG0640	Transcriptional regulator
CXD87_RS04665	COG3220	belongs to the UPF0276 family
CXD87_RS04710	COG1666	GTP binding
CXD87_RS04745	COG0312	modulator of DNA gyrase
CXD87_RS04750	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CXD87_RS04755	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CXD87_RS04755	COG3064	Membrane
CXD87_RS04755	COG3210	domain, Protein
CXD87_RS04755	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CXD87_RS04755	COG3210	domain, Protein
CXD87_RS04755	COG3064	Membrane
CXD87_RS04760	COG0277	FAD linked oxidase domain protein
CXD87_RS04765	COG0277	FAD linked oxidase domain protein
CXD87_RS04770	COG0277	FAD linked oxidase domain protein
CXD87_RS04775	COG0247	lactate metabolic process
CXD87_RS04780	COG2819	hydrolase of the alpha beta superfamily
CXD87_RS04820	COG0583	DNA-binding transcription factor activity
CXD87_RS04825	COG0482	sulfurtransferase activity
CXD87_RS04830	COG0730	response to heat
CXD87_RS04835	COG0625	glutathione transferase activity
CXD87_RS04840	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CXD87_RS04845	COG3909	cytochrome
CXD87_RS04885	COG0154	amidase activity
CXD87_RS04890	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CXD87_RS04895	COG1024	Enoyl-CoA hydratase
CXD87_RS04910	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CXD87_RS04925	COG1028	Short-chain dehydrogenase reductase Sdr
CXD87_RS04930	COG1414	Transcriptional regulator
CXD87_RS04940	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CXD87_RS04945	COG0251	oxidation-reduction process
CXD87_RS04950	COG0559	Belongs to the binding-protein-dependent transport system permease family
CXD87_RS04985	COG0583	DNA-binding transcription factor activity
CXD87_RS04995	COG0590	tRNA wobble adenosine to inosine editing
CXD87_RS05000	COG2807	transmembrane transport
CXD87_RS05020	COG0154	amidase activity
CXD87_RS05025	COG0307	riboflavin synthase, alpha
CXD87_RS05030	COG3181	Tripartite tricarboxylate transporter family receptor
CXD87_RS05035	COG1522	sequence-specific DNA binding
CXD87_RS05045	COG0318	PFAM AMP-dependent synthetase and ligase
CXD87_RS05055	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CXD87_RS05075	COG1063	alcohol dehydrogenase
CXD87_RS05100	COG1418	mRNA catabolic process
CXD87_RS05105	COG1448	Aminotransferase
CXD87_RS05110	COG0583	DNA-binding transcription factor activity
CXD87_RS05120	COG0477	Major facilitator Superfamily
CXD87_RS05125	COG1028	Short-chain dehydrogenase reductase Sdr
CXD87_RS05140	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CXD87_RS05145	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CXD87_RS05150	COG0583	DNA-binding transcription factor activity
CXD87_RS05210	COG1028	Short-chain dehydrogenase reductase Sdr
CXD87_RS05215	COG1309	transcriptional regulator
CXD87_RS05225	COG2982	Protein involved in outer membrane biogenesis
CXD87_RS05230	COG2818	Glycosylase
CXD87_RS05250	COG1653	transport
CXD87_RS05265	COG3842	ATPase activity
CXD87_RS05270	COG0395	ABC-type sugar transport system, permease component
CXD87_RS05275	COG1175	transmembrane transport
CXD87_RS05295	COG3181	Tripartite tricarboxylate transporter family receptor
CXD87_RS05300	COG2186	Transcriptional regulator
CXD87_RS05330	COG1454	alcohol dehydrogenase
CXD87_RS05350	COG2011	ABC-type metal ion transport system permease component
CXD87_RS05355	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CXD87_RS05360	COG1501	Belongs to the glycosyl hydrolase 31 family
CXD87_RS05385	COG0318	PFAM AMP-dependent synthetase and ligase
CXD87_RS05390	COG1473	amidohydrolase
CXD87_RS05400	COG2855	membrane
CXD87_RS05410	COG2239	Acts as a magnesium transporter
CXD87_RS05430	COG3181	Tripartite tricarboxylate transporter family receptor
CXD87_RS05440	COG1722	exodeoxyribonuclease VII activity
CXD87_RS05445	COG0142	geranyltranstransferase activity
CXD87_RS05450	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CXD87_RS05455	COG1469	GTP cyclohydrolase I activity
CXD87_RS05460	COG0360	Binds together with S18 to 16S ribosomal RNA
CXD87_RS05465	COG2965	DNA replication, synthesis of RNA primer
CXD87_RS05470	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CXD87_RS05475	COG0359	binds to the 23S rRNA
CXD87_RS05485	COG0305	Participates in initiation and elongation during chromosome replication
CXD87_RS05495	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CXD87_RS05500	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CXD87_RS05505	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CXD87_RS05510	COG3737	Protein of unknown function (DUF498/DUF598)
CXD87_RS05515	COG0436	Aminotransferase
CXD87_RS05540	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CXD87_RS05575	COG0268	Binds directly to 16S ribosomal RNA
CXD87_RS05585	COG0728	peptidoglycan biosynthetic process
CXD87_RS05595	COG0563	adenylate kinase activity
CXD87_RS05600	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CXD87_RS05605	COG2835	tetraacyldisaccharide 4'-kinase activity
CXD87_RS05610	COG1663	tetraacyldisaccharide 4'-kinase activity
CXD87_RS05615	COG0848	biopolymer transport protein
CXD87_RS05620	COG0811	peptide transport
CXD87_RS05630	COG1570	exodeoxyribonuclease VII activity
CXD87_RS05635	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CXD87_RS05640	COG0038	chloride channel
CXD87_RS05645	COG0183	Belongs to the thiolase family
CXD87_RS05655	COG1278	Cold shock
CXD87_RS05660	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CXD87_RS05670	COG4953	penicillin-binding protein 1C
CXD87_RS05675	COG0542	response to heat
CXD87_RS05680	COG2995	paraquat-inducible protein a
CXD87_RS05685	COG3008	intermembrane lipid transfer
CXD87_RS05685	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CXD87_RS05695	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CXD87_RS05695	COG0506	proline dehydrogenase activity
CXD87_RS05695	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CXD87_RS05730	COG2271	Major facilitator Superfamily
CXD87_RS05735	COG1309	transcriptional regulator
CXD87_RS05770	COG0477	Major facilitator Superfamily
CXD87_RS05780	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CXD87_RS05785	COG1845	cytochrome c oxidase, subunit III
CXD87_RS05790	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CXD87_RS05800	COG1028	Short-chain dehydrogenase reductase Sdr
CXD87_RS05820	COG0789	Transcriptional regulator
CXD87_RS05845	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CXD87_RS05850	COG0697	spore germination
CXD87_RS05860	COG0678	peroxiredoxin activity
CXD87_RS05870	COG0412	Dienelactone hydrolase
CXD87_RS05880	COG0315	cyclic pyranopterin monophosphate synthase activity
CXD87_RS05895	COG0521	Mo-molybdopterin cofactor biosynthetic process
CXD87_RS05900	COG0303	'Molybdopterin
CXD87_RS05905	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CXD87_RS05925	COG0165	Argininosuccinate lyase
CXD87_RS05930	COG0668	transmembrane transport
CXD87_RS05975	COG0747	negative chemotaxis
CXD87_RS05980	COG0601	transmembrane transport
CXD87_RS05995	COG1162	GTPase activity
CXD87_RS06000	COG0501	Belongs to the peptidase M48B family
CXD87_RS06005	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CXD87_RS06015	COG3327	negative regulation of DNA-templated transcription, initiation
CXD87_RS06020	COG3396	Phenylacetate-CoA oxygenase
CXD87_RS06025	COG3460	Phenylacetate-CoA oxygenase
CXD87_RS06030	COG3396	Phenylacetate-CoA oxygenase
CXD87_RS06035	COG2151	metal-sulfur cluster biosynthetic enzyme
CXD87_RS06055	COG1012	belongs to the aldehyde dehydrogenase family
CXD87_RS06060	COG1024	Enoyl-CoA hydratase
CXD87_RS06065	COG2050	protein possibly involved in aromatic compounds catabolism
CXD87_RS06075	COG3539	Fimbrial protein
CXD87_RS06095	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CXD87_RS06100	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CXD87_RS06100	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CXD87_RS06105	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CXD87_RS06110	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CXD87_RS06110	COG0047	phosphoribosylformylglycinamidine synthase activity
CXD87_RS06115	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CXD87_RS06115	COG3210	domain, Protein
CXD87_RS06115	COG3064	Membrane
CXD87_RS06145	COG0235	Class ii aldolase
CXD87_RS06150	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CXD87_RS06155	COG0720	synthase
CXD87_RS06160	COG0602	queuosine metabolic process
CXD87_RS06185	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CXD87_RS06220	COG3181	Tripartite tricarboxylate transporter family receptor
CXD87_RS06245	COG3842	ATPase activity
CXD87_RS06255	COG0395	ABC-type sugar transport system, permease component
CXD87_RS06285	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CXD87_RS06290	COG0420	3'-5' exonuclease activity
CXD87_RS06335	COG0519	Catalyzes the synthesis of GMP from XMP
CXD87_RS06335	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CXD87_RS06350	COG3550	peptidyl-serine autophosphorylation
CXD87_RS06360	COG0477	Major facilitator Superfamily
CXD87_RS06375	COG1228	amidohydrolase
CXD87_RS06385	COG1116	anion transmembrane transporter activity
CXD87_RS06390	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CXD87_RS06425	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CXD87_RS06445	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CXD87_RS06475	COG2814	Major facilitator Superfamily
CXD87_RS06490	COG1280	lysine exporter protein (LysE YggA)
CXD87_RS06505	COG0747	negative chemotaxis
CXD87_RS06510	COG0601	transmembrane transport
CXD87_RS06515	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CXD87_RS06520	COG4172	Belongs to the ABC transporter superfamily
CXD87_RS06525	COG1609	Transcriptional regulator
CXD87_RS06555	COG0586	Pfam SNARE associated Golgi protein
CXD87_RS06570	COG0500	methyltransferase
CXD87_RS06585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CXD87_RS06595	COG0756	dUTP diphosphatase activity
CXD87_RS06605	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CXD87_RS06610	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CXD87_RS06615	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CXD87_RS06620	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CXD87_RS06620	COG0072	phenylalanine-tRNA ligase activity
CXD87_RS06625	COG0776	regulation of translation
CXD87_RS06690	COG0540	Belongs to the ATCase OTCase family
CXD87_RS06695	COG2974	May be involved in recombination
CXD87_RS06705	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CXD87_RS06710	COG0583	DNA-binding transcription factor activity
CXD87_RS06730	COG1028	Short-chain dehydrogenase reductase Sdr
CXD87_RS06745	COG3842	ATPase activity
CXD87_RS06750	COG1250	3-hydroxyacyl-CoA dehydrogenase
CXD87_RS06750	COG1024	Enoyl-CoA hydratase
CXD87_RS06770	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CXD87_RS06775	COG2137	regulation of response to DNA damage stimulus
CXD87_RS06785	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CXD87_RS06795	COG0045	succinate-CoA ligase (ADP-forming) activity
CXD87_RS06800	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CXD87_RS06805	COG0861	Integral membrane protein TerC family
CXD87_RS06810	COG0861	Integral membrane protein TerC family
CXD87_RS06815	COG0181	hydroxymethylbilane synthase activity
CXD87_RS06875	COG4964	Belongs to the GSP D family
CXD87_RS06900	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CXD87_RS06910	COG0583	DNA-binding transcription factor activity
CXD87_RS06920	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CXD87_RS06925	COG4311	Sarcosine oxidase, delta subunit
CXD87_RS06930	COG0446	pyridine nucleotide-disulphide oxidoreductase
CXD87_RS06930	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CXD87_RS06965	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CXD87_RS06970	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CXD87_RS06975	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CXD87_RS06980	COG0735	belongs to the Fur family
CXD87_RS06985	COG0497	DNA recombination
CXD87_RS06990	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CXD87_RS06995	COG1420	regulation of RNA biosynthetic process
CXD87_RS07000	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CXD87_RS07010	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CXD87_RS07020	COG0443	Heat shock 70 kDa protein
CXD87_RS07030	COG0612	Peptidase, M16
CXD87_RS07050	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CXD87_RS07095	COG0745	RESPONSE REGULATOR receiver
CXD87_RS07105	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CXD87_RS07110	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CXD87_RS07115	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CXD87_RS07130	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CXD87_RS07150	COG1193	negative regulation of DNA recombination
CXD87_RS07155	COG0492	ferredoxin-NADP+ reductase activity
CXD87_RS07160	COG1674	ftsk spoiiie
CXD87_RS07165	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CXD87_RS07170	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CXD87_RS07175	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CXD87_RS07200	COG3706	GGDEF domain
CXD87_RS07220	COG2814	Major facilitator Superfamily
CXD87_RS07250	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CXD87_RS07265	COG1028	Short-chain dehydrogenase reductase Sdr
CXD87_RS07275	COG3022	response to hydroperoxide
CXD87_RS07315	COG2197	response regulator
CXD87_RS07320	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CXD87_RS07325	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CXD87_RS07330	COG0189	ligase activity
CXD87_RS07340	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXD87_RS07345	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CXD87_RS07360	COG2423	ornithine cyclodeaminase activity
CXD87_RS07370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXD87_RS07375	COG0765	amino acid transport
CXD87_RS07380	COG0765	amino acid transport
CXD87_RS07385	COG1126	abc transporter atp-binding protein
CXD87_RS07440	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CXD87_RS07450	COG2944	sequence-specific DNA binding
CXD87_RS07460	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CXD87_RS07465	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CXD87_RS07470	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CXD87_RS07475	COG0009	L-threonylcarbamoyladenylate synthase
CXD87_RS07480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXD87_RS07485	COG1414	Transcriptional regulator
CXD87_RS07500	COG0765	amino acid transport
CXD87_RS07505	COG1126	abc transporter atp-binding protein
CXD87_RS07510	COG0028	Belongs to the TPP enzyme family
CXD87_RS07525	COG0028	Belongs to the TPP enzyme family
CXD87_RS07530	COG0583	DNA-binding transcription factor activity
CXD87_RS07535	COG4974	Belongs to the 'phage' integrase family
CXD87_RS07540	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CXD87_RS07545	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CXD87_RS07560	COG1686	Belongs to the peptidase S11 family
CXD87_RS07570	COG2814	Major facilitator Superfamily
CXD87_RS07580	COG1074	ATP-dependent DNA helicase activity
CXD87_RS07590	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CXD87_RS07595	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CXD87_RS07600	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CXD87_RS07620	COG2321	neutral zinc metallopeptidase
CXD87_RS07625	COG0009	L-threonylcarbamoyladenylate synthase
CXD87_RS07675	COG3360	Dodecin
CXD87_RS07680	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CXD87_RS07685	COG2850	peptidyl-arginine hydroxylation
CXD87_RS07690	COG3539	Fimbrial protein
CXD87_RS07695	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CXD87_RS07700	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CXD87_RS07715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXD87_RS07720	COG0765	amino acid transport
CXD87_RS07725	COG1126	abc transporter atp-binding protein
CXD87_RS07730	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CXD87_RS07735	COG1758	RNA polymerase activity
CXD87_RS07740	COG0194	GDP metabolic process
CXD87_RS07745	COG3258	Cytochrome c
CXD87_RS07750	COG2863	cytochrome
CXD87_RS07755	COG1028	Short-chain dehydrogenase reductase Sdr
CXD87_RS07760	COG0791	NLP P60 protein
CXD87_RS07765	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CXD87_RS07785	COG1561	YicC-like family, N-terminal region
CXD87_RS07790	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CXD87_RS07810	COG2200	EAL domain
CXD87_RS07810	COG2199	diguanylate cyclase activity
CXD87_RS07815	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CXD87_RS07825	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CXD87_RS07830	COG0174	glutamine synthetase
CXD87_RS07840	COG2204	response regulator
CXD87_RS07845	COG0583	DNA-binding transcription factor activity
CXD87_RS07850	COG1741	Belongs to the pirin family
CXD87_RS07855	COG1741	Belongs to the pirin family
CXD87_RS07865	COG3842	ATPase activity
CXD87_RS07870	COG1178	ABC-type Fe3 transport system permease component
CXD87_RS07875	COG1840	ABC-type Fe3 transport system, periplasmic component
CXD87_RS07885	COG0583	DNA-binding transcription factor activity
CXD87_RS07895	COG0656	L-ascorbic acid biosynthetic process
CXD87_RS07910	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CXD87_RS07915	COG0583	DNA-binding transcription factor activity
CXD87_RS07930	COG0783	Belongs to the Dps family
CXD87_RS07950	COG0463	Glycosyl transferase, family 2
CXD87_RS07970	COG0438	transferase activity, transferring glycosyl groups
CXD87_RS07985	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CXD87_RS08010	COG0300	oxidoreductase activity
CXD87_RS08055	COG0861	Integral membrane protein TerC family
CXD87_RS08060	COG1028	Short-chain dehydrogenase reductase Sdr
CXD87_RS08080	COG0714	Associated with various cellular activities
CXD87_RS08115	COG3119	arylsulfatase activity
CXD87_RS08140	COG2197	response regulator
CXD87_RS08150	COG2944	sequence-specific DNA binding
CXD87_RS08160	COG0625	glutathione transferase activity
CXD87_RS08190	COG0179	Fumarylacetoacetate (FAA) hydrolase
CXD87_RS08195	COG1028	Short-chain dehydrogenase reductase Sdr
CXD87_RS08240	COG0431	NADPH-dependent FMN reductase
CXD87_RS08270	COG1028	Short-chain dehydrogenase reductase Sdr
CXD87_RS08275	COG0583	DNA-binding transcription factor activity
CXD87_RS08295	COG2111	Na H antiporter
CXD87_RS08295	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CXD87_RS08300	COG1006	Multisubunit Na H antiporter MnhC subunit
CXD87_RS08305	COG0651	ATP synthesis coupled electron transport
CXD87_RS08310	COG1863	multisubunit Na H antiporter MnhE subunit
CXD87_RS08315	COG2212	antiporter activity
CXD87_RS08340	COG0590	tRNA wobble adenosine to inosine editing
CXD87_RS08345	COG1619	proteins homologs of microcin C7 resistance protein MccF
CXD87_RS08350	COG1024	Enoyl-CoA hydratase
CXD87_RS08365	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CXD87_RS08370	COG0488	(ABC) transporter
CXD87_RS08405	COG1017	nitric oxide dioxygenase activity
CXD87_RS08405	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CXD87_RS08410	COG1959	2 iron, 2 sulfur cluster binding
CXD87_RS08415	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CXD87_RS08435	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CXD87_RS08440	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CXD87_RS08445	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CXD87_RS08450	COG0084	hydrolase, TatD family'
CXD87_RS08465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXD87_RS08475	COG1126	abc transporter atp-binding protein
CXD87_RS08485	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CXD87_RS08500	COG0028	Belongs to the TPP enzyme family
CXD87_RS08510	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CXD87_RS08510	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CXD87_RS08520	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CXD87_RS08570	COG4336	lyase activity
CXD87_RS08580	COG2205	protein histidine kinase activity
CXD87_RS08580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXD87_RS08585	COG2197	response regulator
CXD87_RS08590	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CXD87_RS08590	COG3210	domain, Protein
CXD87_RS08590	COG3064	Membrane
CXD87_RS08600	COG3121	Chaperone
CXD87_RS08605	COG3188	usher protein
CXD87_RS08610	COG3539	Fimbrial protein
CXD87_RS08615	COG2831	hemolysin activation secretion protein
CXD87_RS08630	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CXD87_RS08680	COG0668	transmembrane transport
CXD87_RS08700	COG0483	inositol monophosphate 1-phosphatase activity
CXD87_RS08705	COG1253	flavin adenine dinucleotide binding
CXD87_RS08710	COG1968	undecaprenyl-diphosphatase activity
CXD87_RS08715	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CXD87_RS08730	COG0215	cysteine-tRNA ligase activity
CXD87_RS08740	COG0825	malonyl-CoA metabolic process
CXD87_RS08750	COG0037	tRNA processing
CXD87_RS08755	COG0527	aspartate kinase activity
CXD87_RS08780	COG1250	3-hydroxyacyl-CoA dehydrogenase
CXD87_RS08785	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CXD87_RS08785	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CXD87_RS08800	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CXD87_RS08805	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
CXD87_RS08810	COG1028	Short-chain dehydrogenase reductase Sdr
CXD87_RS08820	COG0583	DNA-binding transcription factor activity
CXD87_RS08845	COG3842	ATPase activity
CXD87_RS08855	COG0446	pyridine nucleotide-disulphide oxidoreductase
CXD87_RS08855	COG1902	pentaerythritol trinitrate reductase activity
CXD87_RS08860	COG1414	Transcriptional regulator
CXD87_RS08865	COG1832	CoA-binding protein
CXD87_RS08875	COG0251	oxidation-reduction process
CXD87_RS08900	COG1902	pentaerythritol trinitrate reductase activity
CXD87_RS08910	COG1215	transferase activity, transferring glycosyl groups
CXD87_RS08915	COG0726	polysaccharide deacetylase
CXD87_RS08915	COG1649	PFAM Uncharacterised BCR, COG1649
CXD87_RS08935	COG1846	Transcriptional regulator
CXD87_RS08940	COG2197	response regulator
CXD87_RS08955	COG0166	Belongs to the GPI family
CXD87_RS08960	COG1045	serine acetyltransferase
CXD87_RS08970	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CXD87_RS08975	COG0483	inositol monophosphate 1-phosphatase activity
CXD87_RS08980	COG1012	belongs to the aldehyde dehydrogenase family
CXD87_RS08985	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CXD87_RS09000	COG0210	DNA helicase
CXD87_RS09005	COG0598	Magnesium transport protein CorA
CXD87_RS09015	COG0747	negative chemotaxis
CXD87_RS09020	COG0601	transmembrane transport
CXD87_RS09025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CXD87_RS09030	COG4172	Belongs to the ABC transporter superfamily
CXD87_RS09035	COG1846	Transcriptional regulator
CXD87_RS09090	COG4964	Belongs to the GSP D family
CXD87_RS09130	COG2204	response regulator
CXD87_RS09145	COG1595	DNA-templated transcription, initiation
CXD87_RS09155	COG3474	cytochrome
CXD87_RS09160	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CXD87_RS09175	COG3384	dioxygenase
CXD87_RS09180	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CXD87_RS09210	COG2885	chlorophyll binding
CXD87_RS09245	COG0697	spore germination
CXD87_RS09250	COG0730	response to heat
CXD87_RS09270	COG0583	DNA-binding transcription factor activity
CXD87_RS09275	COG0427	acetyl-CoA hydrolase
CXD87_RS09330	COG1250	3-hydroxyacyl-CoA dehydrogenase
CXD87_RS09335	COG0154	amidase activity
CXD87_RS09345	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CXD87_RS09360	COG0495	leucyl-tRNA aminoacylation
CXD87_RS09365	COG2814	Major facilitator Superfamily
CXD87_RS09400	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CXD87_RS09405	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CXD87_RS09410	COG2814	Major facilitator Superfamily
CXD87_RS09430	COG4176	ABC-type proline glycine betaine transport system permease component
CXD87_RS09440	COG1942	4-Oxalocrotonate Tautomerase
CXD87_RS09445	COG0183	Belongs to the thiolase family
CXD87_RS09455	COG1802	Transcriptional regulator
CXD87_RS09465	COG1024	Enoyl-CoA hydratase
CXD87_RS09480	COG2032	superoxide dismutase activity
CXD87_RS09495	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CXD87_RS09520	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CXD87_RS09525	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CXD87_RS09535	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CXD87_RS09540	COG0736	holo-[acyl-carrier-protein] synthase activity
CXD87_RS09545	COG1472	Belongs to the glycosyl hydrolase 3 family
CXD87_RS09550	COG0322	excinuclease ABC activity
CXD87_RS09555	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CXD87_RS09565	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CXD87_RS09565	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CXD87_RS09570	COG2224	Isocitrate lyase
CXD87_RS09595	COG0559	Belongs to the binding-protein-dependent transport system permease family
CXD87_RS09605	COG4638	Rieske (2fe-2S)
CXD87_RS09615	COG1024	Enoyl-CoA hydratase
CXD87_RS09625	COG0633	Ferredoxin
CXD87_RS09630	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CXD87_RS09645	COG0183	Belongs to the thiolase family
CXD87_RS09660	COG0583	DNA-binding transcription factor activity
CXD87_RS09690	COG2346	COG2346, Truncated hemoglobins
CXD87_RS09820	COG2207	Transcriptional regulator
CXD87_RS09870	COG1132	(ABC) transporter
CXD87_RS09895	COG0659	secondary active sulfate transmembrane transporter activity
CXD87_RS09925	COG2169	Transcriptional regulator
CXD87_RS09930	COG5507	3-demethylubiquinone-9 3-methyltransferase
CXD87_RS09935	COG0384	phenazine biosynthesis protein PhzF
CXD87_RS09940	COG0583	DNA-binding transcription factor activity
CXD87_RS09945	COG2733	membrane
CXD87_RS09960	COG1012	belongs to the aldehyde dehydrogenase family
CXD87_RS09965	COG3284	Transcriptional regulator
CXD87_RS09990	COG1380	Effector of murein hydrolase LrgA
CXD87_RS09995	COG4106	trans-aconitate 2-methyltransferase activity
CXD87_RS09995	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CXD87_RS10005	COG0156	8-amino-7-oxononanoate synthase activity
CXD87_RS10075	COG1131	(ABC) transporter
CXD87_RS10080	COG0842	Transport permease protein
CXD87_RS10085	COG0628	permease
CXD87_RS10120	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CXD87_RS10130	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CXD87_RS10135	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CXD87_RS10140	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CXD87_RS10145	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CXD87_RS10150	COG0330	HflC and HflK could
CXD87_RS10155	COG0330	HflC and HflK could
CXD87_RS10160	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CXD87_RS10165	COG1923	regulation of RNA biosynthetic process
CXD87_RS10170	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CXD87_RS10175	COG1160	GTP binding
CXD87_RS10180	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CXD87_RS10185	COG2976	Protein conserved in bacteria
CXD87_RS10190	COG0124	histidyl-tRNA synthetase
CXD87_RS10195	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CXD87_RS10205	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CXD87_RS10210	COG0105	UTP biosynthetic process
CXD87_RS10215	COG0525	valine-tRNA ligase activity
CXD87_RS10230	COG0642	Histidine kinase
CXD87_RS10255	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CXD87_RS10260	COG0336	Belongs to the RNA methyltransferase TrmD family
CXD87_RS10265	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CXD87_RS10270	COG0228	four-way junction DNA binding
CXD87_RS10280	COG0425	Belongs to the sulfur carrier protein TusA family
CXD87_RS10285	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CXD87_RS10330	COG0154	amidase activity
CXD87_RS10335	COG4172	Belongs to the ABC transporter superfamily
CXD87_RS10340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CXD87_RS10345	COG0601	transmembrane transport
CXD87_RS10350	COG0747	negative chemotaxis
CXD87_RS10380	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CXD87_RS10390	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CXD87_RS10410	COG3395	kinase activity
CXD87_RS10425	COG1024	Enoyl-CoA hydratase
CXD87_RS10445	COG0633	Ferredoxin
CXD87_RS10450	COG0443	Heat shock 70 kDa protein
CXD87_RS10455	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CXD87_RS10460	COG0316	Belongs to the HesB IscA family
CXD87_RS10465	COG0822	iron-sulfur transferase activity
CXD87_RS10470	COG1104	cysteine desulfurase activity
CXD87_RS10480	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CXD87_RS10485	COG0556	nucleotide-excision repair
CXD87_RS10495	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CXD87_RS10525	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CXD87_RS10545	COG1028	Short-chain dehydrogenase reductase Sdr
CXD87_RS10550	COG0183	Belongs to the thiolase family
CXD87_RS10560	COG1024	Enoyl-CoA hydratase
CXD87_RS10575	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CXD87_RS10580	COG0583	DNA-binding transcription factor activity
CXD87_RS10585	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CXD87_RS10590	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CXD87_RS10595	COG0740	serine-type endopeptidase activity
CXD87_RS10600	COG0544	peptidyl-prolyl cis-trans isomerase activity
CXD87_RS10610	COG1278	Cold shock
CXD87_RS10620	COG1278	Cold shock
CXD87_RS10655	COG2171	N-acyltransferase activity
CXD87_RS10660	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CXD87_RS10665	COG2890	protein-(glutamine-N5) methyltransferase activity
CXD87_RS10670	COG0488	(ABC) transporter
CXD87_RS10675	COG4771	TonB-dependent receptor
CXD87_RS10680	COG0210	DNA helicase
CXD87_RS10700	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CXD87_RS10705	COG0196	riboflavin kinase activity
CXD87_RS10710	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CXD87_RS10715	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CXD87_RS10720	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CXD87_RS10730	COG1522	sequence-specific DNA binding
CXD87_RS10750	COG2951	lytic endotransglycosylase activity
CXD87_RS10755	COG2833	Protein of unknown function (DUF455)
CXD87_RS10775	COG0189	ligase activity
CXD87_RS10775	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CXD87_RS10780	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CXD87_RS10780	COG1181	Belongs to the D-alanine--D-alanine ligase family
CXD87_RS10785	COG3237	CsbD-like
CXD87_RS10795	COG2823	Periplasmic or secreted lipoprotein
CXD87_RS10810	COG4181	ATPase activity
CXD87_RS10820	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CXD87_RS10825	COG0584	glycerophosphoryl diester phosphodiesterase
CXD87_RS10830	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CXD87_RS10840	COG0678	peroxiredoxin activity
CXD87_RS10840	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CXD87_RS10850	COG0789	Transcriptional regulator
CXD87_RS10855	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CXD87_RS10885	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CXD87_RS10890	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CXD87_RS10900	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CXD87_RS10905	COG2252	PERMEase
CXD87_RS10915	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CXD87_RS10945	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CXD87_RS10950	COG2358	TRAP transporter, solute receptor (TAXI family
CXD87_RS10985	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CXD87_RS10990	COG1366	Belongs to the anti-sigma-factor antagonist family
CXD87_RS10995	COG2172	sigma factor antagonist activity
CXD87_RS11000	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CXD87_RS11010	COG2208	phosphoserine phosphatase activity
CXD87_RS11010	COG2770	Histidine kinase
CXD87_RS11035	COG1595	DNA-templated transcription, initiation
CXD87_RS11050	COG4792	protein secretion
CXD87_RS11055	COG4791	protein targeting
CXD87_RS11060	COG4794	Type iii secretion
CXD87_RS11065	COG4790	Type iii secretion
CXD87_RS11100	COG4669	(LipO)protein
CXD87_RS11165	COG4789	Type iii secretion
CXD87_RS11195	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CXD87_RS11200	COG0840	transmembrane signaling receptor activity
CXD87_RS11205	COG2233	PERMEase
CXD87_RS11230	COG1840	ABC-type Fe3 transport system, periplasmic component
CXD87_RS11235	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CXD87_RS11240	COG1178	ABC-type Fe3 transport system permease component
CXD87_RS11245	COG3842	ATPase activity
CXD87_RS11250	COG0583	DNA-binding transcription factor activity
CXD87_RS11270	COG0501	Belongs to the peptidase M48B family
CXD87_RS11280	COG0697	spore germination
CXD87_RS11290	COG1846	Transcriptional regulator
CXD87_RS11300	COG1566	PFAM secretion protein HlyD family protein
CXD87_RS11305	COG2814	Major facilitator Superfamily
CXD87_RS11310	COG0473	3-isopropylmalate dehydrogenase activity
CXD87_RS11320	COG0747	negative chemotaxis
CXD87_RS11330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CXD87_RS11345	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CXD87_RS11370	COG1012	belongs to the aldehyde dehydrogenase family
CXD87_RS11380	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CXD87_RS11385	COG1115	amino acid carrier protein
CXD87_RS11390	COG0433	COG0433 Predicted ATPase
CXD87_RS11395	COG0217	transcriptional regulatory protein
CXD87_RS11400	COG0151	Belongs to the GarS family
CXD87_RS11405	COG0408	coproporphyrinogen oxidase activity
CXD87_RS11410	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CXD87_RS11415	COG0799	negative regulation of ribosome biogenesis
CXD87_RS11420	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CXD87_RS11425	COG0424	maF-like protein
CXD87_RS11430	COG3468	outer membrane autotransporter barrel domain protein
CXD87_RS11470	COG1530	ribonuclease E activity
CXD87_RS11475	COG0077	Prephenate dehydratase
CXD87_RS11490	COG1132	(ABC) transporter
CXD87_RS11495	COG0859	PFAM glycosyl transferase family 9
CXD87_RS11520	COG2194	sulfuric ester hydrolase activity
CXD87_RS11525	COG0438	transferase activity, transferring glycosyl groups
CXD87_RS11530	COG0463	Glycosyl transferase, family 2
CXD87_RS11535	COG0726	polysaccharide deacetylase
CXD87_RS11540	COG0438	transferase activity, transferring glycosyl groups
CXD87_RS11555	COG1643	Atp-dependent helicase
CXD87_RS11560	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CXD87_RS11560	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CXD87_RS11565	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CXD87_RS11575	COG0704	Plays a role in the regulation of phosphate uptake
CXD87_RS11580	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CXD87_RS11585	COG1960	acyl-CoA dehydrogenase activity
CXD87_RS11610	COG1177	transmembrane transport
CXD87_RS11615	COG1176	ABC-type spermidine putrescine transport system, permease component I
CXD87_RS11620	COG3842	ATPase activity
CXD87_RS11625	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CXD87_RS11640	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CXD87_RS11645	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CXD87_RS11655	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CXD87_RS11655	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CXD87_RS11670	COG0372	Belongs to the citrate synthase family
CXD87_RS11675	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CXD87_RS11680	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CXD87_RS11685	COG1053	succinate dehydrogenase
CXD87_RS11690	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CXD87_RS11695	COG2009	succinate dehydrogenase
CXD87_RS11700	COG2188	Transcriptional regulator
CXD87_RS11705	COG0039	L-malate dehydrogenase activity
CXD87_RS11735	COG1981	membrane
CXD87_RS11760	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CXD87_RS11770	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CXD87_RS11800	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CXD87_RS11805	COG0148	phosphopyruvate hydratase activity
CXD87_RS11815	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CXD87_RS11820	COG0504	CTP synthase activity
CXD87_RS11845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CXD87_RS11855	COG0747	negative chemotaxis
CXD87_RS11860	COG4172	Belongs to the ABC transporter superfamily
CXD87_RS11865	COG1446	asparaginase
CXD87_RS11895	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CXD87_RS11910	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CXD87_RS11915	COG0697	spore germination
CXD87_RS11920	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CXD87_RS11930	COG3193	protein, possibly involved in utilization of glycolate and propanediol
CXD87_RS11940	COG0791	NLP P60 protein
CXD87_RS11955	COG0583	DNA-binding transcription factor activity
CXD87_RS11970	COG0583	DNA-binding transcription factor activity
CXD87_RS11980	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CXD87_RS11995	COG0670	Belongs to the BI1 family
CXD87_RS12000	COG3181	Tripartite tricarboxylate transporter family receptor
CXD87_RS12015	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CXD87_RS12025	COG1381	Involved in DNA repair and RecF pathway recombination
CXD87_RS12030	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CXD87_RS12035	COG0571	ribonuclease III activity
CXD87_RS12040	COG0681	Belongs to the peptidase S26 family
CXD87_RS12045	COG0481	GTPase activity
CXD87_RS12050	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CXD87_RS12075	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CXD87_RS12080	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CXD87_RS12095	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CXD87_RS12100	COG0416	fatty acid biosynthetic process
CXD87_RS12105	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CXD87_RS12110	COG1399	metal-binding, possibly nucleic acid-binding protein
CXD87_RS12115	COG0424	maF-like protein
CXD87_RS12125	COG3023	N-Acetylmuramoyl-L-alanine amidase
CXD87_RS12140	COG3022	response to hydroperoxide
CXD87_RS12155	COG0135	phosphoribosylanthranilate isomerase activity
CXD87_RS12170	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CXD87_RS12175	COG0101	tRNA pseudouridine synthase activity
CXD87_RS12185	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CXD87_RS12190	COG0473	3-isopropylmalate dehydrogenase activity
CXD87_RS12195	COG0066	3-isopropylmalate dehydratase activity
CXD87_RS12200	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CXD87_RS12210	COG1122	ATPase activity
CXD87_RS12245	COG3383	formate dehydrogenase (NAD+) activity
CXD87_RS12245	COG0243	molybdopterin cofactor binding
CXD87_RS12275	COG0489	protein tyrosine kinase activity
CXD87_RS12280	COG0746	molybdenum cofactor guanylyltransferase activity
CXD87_RS12285	COG0303	'Molybdopterin
CXD87_RS12290	COG1763	Mo-molybdopterin cofactor biosynthetic process
CXD87_RS12300	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CXD87_RS12305	COG5001	Diguanylate cyclase
CXD87_RS12325	COG3842	ATPase activity
CXD87_RS12335	COG0406	alpha-ribazole phosphatase activity
CXD87_RS12345	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CXD87_RS12350	COG0505	Belongs to the CarA family
CXD87_RS12355	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CXD87_RS12390	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CXD87_RS12395	COG1960	acyl-CoA dehydrogenase activity
CXD87_RS12405	COG2867	negative regulation of translational initiation
CXD87_RS12415	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CXD87_RS12420	COG3706	GGDEF domain
CXD87_RS12425	COG0330	HflC and HflK could
CXD87_RS12440	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CXD87_RS12440	COG0519	Catalyzes the synthesis of GMP from XMP
CXD87_RS12450	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CXD87_RS12455	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CXD87_RS12460	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CXD87_RS12465	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CXD87_RS12475	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CXD87_RS12480	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CXD87_RS12485	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CXD87_RS12490	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CXD87_RS12495	COG0750	zinc metalloprotease
CXD87_RS12500	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CXD87_RS12510	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CXD87_RS12515	COG0233	cytoplasmic translational termination
CXD87_RS12520	COG0528	UMP kinase activity
CXD87_RS12525	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CXD87_RS12530	COG0052	Belongs to the universal ribosomal protein uS2 family
CXD87_RS12535	COG0024	Methionine aminopeptidase
CXD87_RS12540	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CXD87_RS12570	COG0285	dihydrofolate synthase activity
CXD87_RS12605	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CXD87_RS12615	COG1677	Flagellar hook-basal body complex protein FliE
CXD87_RS12625	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CXD87_RS12635	COG1157	protein secretion by the type III secretion system
CXD87_RS12660	COG1580	Controls the rotational direction of flagella during chemotaxis
CXD87_RS12680	COG1338	Plays a role in the flagellum-specific transport system
CXD87_RS12700	COG0840	transmembrane signaling receptor activity
CXD87_RS12705	COG0840	transmembrane signaling receptor activity
CXD87_RS12710	COG0840	transmembrane signaling receptor activity
CXD87_RS12720	COG1256	bacterial-type flagellum assembly
CXD87_RS12730	COG1706	bacterial-type flagellum-dependent cell motility
CXD87_RS12735	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CXD87_RS12750	COG1749	Flagellar hook protein flgE
CXD87_RS12760	COG1558	bacterial-type flagellum-dependent cell motility
CXD87_RS12765	COG1815	bacterial-type flagellum-dependent cell motility
CXD87_RS12805	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXD87_RS12810	COG0765	amino acid transport
CXD87_RS12815	COG1126	abc transporter atp-binding protein
CXD87_RS12830	COG4948	Mandelate Racemase Muconate Lactonizing
CXD87_RS12835	COG3181	Tripartite tricarboxylate transporter family receptor
CXD87_RS12845	COG0066	3-isopropylmalate dehydratase activity
CXD87_RS12860	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CXD87_RS12870	COG3181	Tripartite tricarboxylate transporter family receptor
CXD87_RS12880	COG1802	Transcriptional regulator
CXD87_RS12895	COG0583	DNA-binding transcription factor activity
CXD87_RS12915	COG1695	Transcriptional regulator
CXD87_RS12925	COG3568	Endonuclease Exonuclease Phosphatase
CXD87_RS12930	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CXD87_RS12980	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CXD87_RS12990	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CXD87_RS13010	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CXD87_RS13040	COG0667	Aldo Keto reductase
CXD87_RS13055	COG2259	Doxx family
CXD87_RS13085	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CXD87_RS13105	COG0386	Belongs to the glutathione peroxidase family
CXD87_RS13110	COG0625	glutathione transferase activity
CXD87_RS13125	COG0095	Lipoate-protein ligase
CXD87_RS13140	COG0688	phosphatidylethanolamine metabolic process
CXD87_RS13150	COG1464	Belongs to the NlpA lipoprotein family
CXD87_RS13165	COG2363	Small membrane protein
CXD87_RS13190	COG3842	ATPase activity
CXD87_RS13195	COG0395	ABC-type sugar transport system, permease component
CXD87_RS13200	COG1175	transmembrane transport
CXD87_RS13205	COG1653	transport
CXD87_RS13215	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CXD87_RS13235	COG0559	Belongs to the binding-protein-dependent transport system permease family
CXD87_RS13255	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CXD87_RS13280	COG2311	Membrane
CXD87_RS13305	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CXD87_RS13315	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CXD87_RS13320	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CXD87_RS13325	COG1760	l-serine dehydratase
CXD87_RS13330	COG1283	sodium-dependent phosphate transmembrane transporter activity
CXD87_RS13335	COG0412	Dienelactone hydrolase
CXD87_RS13350	COG1611	Belongs to the LOG family
CXD87_RS13370	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CXD87_RS13375	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CXD87_RS13380	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CXD87_RS13385	COG2251	uridine kinase activity
CXD87_RS13385	COG0195	Participates in both transcription termination and antitermination
CXD87_RS13390	COG0779	Required for maturation of 30S ribosomal subunits
CXD87_RS13395	COG1187	pseudouridine synthase activity
CXD87_RS13400	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CXD87_RS13410	COG0583	DNA-binding transcription factor activity
CXD87_RS13420	COG0523	cobalamin synthesis protein
CXD87_RS13440	COG0625	glutathione transferase activity
CXD87_RS13445	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CXD87_RS13450	COG1047	Peptidyl-prolyl cis-trans
CXD87_RS13455	COG2003	Belongs to the UPF0758 family
CXD87_RS13460	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CXD87_RS13465	COG3483	tryptophan 2,3-dioxygenase activity
CXD87_RS13470	COG0254	rRNA binding
CXD87_RS13480	COG0534	Mate efflux family protein
CXD87_RS13500	COG2304	oxidoreductase activity
CXD87_RS13520	COG1028	Short-chain dehydrogenase reductase Sdr
CXD87_RS13525	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CXD87_RS13530	COG1562	ergosterol biosynthetic process
CXD87_RS13535	COG1562	ergosterol biosynthetic process
CXD87_RS13540	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CXD87_RS13540	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CXD87_RS13545	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CXD87_RS13555	COG0842	Transport permease protein
CXD87_RS13560	COG1131	(ABC) transporter
CXD87_RS13580	COG1477	protein flavinylation
CXD87_RS13595	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CXD87_RS13610	COG5564	TIM-barrel signal transduction protein
CXD87_RS13615	COG5441	Belongs to the UPF0261 family
CXD87_RS13625	COG3468	outer membrane autotransporter barrel domain protein
CXD87_RS13645	COG0542	response to heat
CXD87_RS13650	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CXD87_RS13665	COG0494	nUDIX hydrolase
CXD87_RS13670	COG3530	Putative quorum-sensing-regulated virulence factor
CXD87_RS13680	COG1595	DNA-templated transcription, initiation
CXD87_RS13685	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CXD87_RS13720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXD87_RS13725	COG0765	amino acid transport
CXD87_RS13730	COG0765	amino acid transport
CXD87_RS13770	COG0672	)-iron permease
CXD87_RS13785	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
CXD87_RS13790	COG1028	Short-chain dehydrogenase reductase Sdr
CXD87_RS13795	COG3243	poly(R)-hydroxyalkanoic acid synthase
CXD87_RS13805	COG0564	pseudouridine synthase activity
CXD87_RS13815	COG1199	ATP-dependent helicase activity
CXD87_RS13820	COG2183	response to ionizing radiation
CXD87_RS13825	COG0180	Tryptophanyl-tRNA synthetase
CXD87_RS13850	COG3181	Tripartite tricarboxylate transporter family receptor
CXD87_RS13860	COG0583	DNA-binding transcription factor activity
CXD87_RS13865	COG1028	Short-chain dehydrogenase reductase Sdr
CXD87_RS13870	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CXD87_RS13875	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CXD87_RS13880	COG0508	dehydrogenase complex catalyzes the overall conversion of
CXD87_RS13885	COG0567	Dehydrogenase, E1 component
CXD87_RS13895	COG1522	sequence-specific DNA binding
CXD87_RS13905	COG0280	phosphate acetyltransferase
CXD87_RS13905	COG0281	malic enzyme
CXD87_RS13910	COG3539	Fimbrial protein
CXD87_RS13930	COG0613	PHP domain protein
CXD87_RS13940	COG0658	competence protein
CXD87_RS13940	COG2333	competence protein COMEC
CXD87_RS13965	COG0084	hydrolase, TatD family'
CXD87_RS13970	COG1136	(ABC) transporter
CXD87_RS13985	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CXD87_RS13995	COG1028	Short-chain dehydrogenase reductase Sdr
CXD87_RS14000	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CXD87_RS14015	COG1022	Amp-dependent synthetase and ligase
CXD87_RS14050	COG2205	protein histidine kinase activity
CXD87_RS14055	COG0745	RESPONSE REGULATOR receiver
CXD87_RS14060	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CXD87_RS14070	COG1295	ribonuclease BN
CXD87_RS14085	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CXD87_RS14115	COG1534	Rna-binding protein
CXD87_RS14120	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CXD87_RS14125	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CXD87_RS14135	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CXD87_RS14145	COG0248	Ppx GppA phosphatase
CXD87_RS14170	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CXD87_RS14185	COG2732	(Barnase) inhibitor
CXD87_RS14195	COG0280	phosphate acetyltransferase
CXD87_RS14195	COG0281	malic enzyme
CXD87_RS14205	COG0436	Aminotransferase
CXD87_RS14215	COG0741	lytic transglycosylase activity
CXD87_RS14220	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CXD87_RS14245	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CXD87_RS14245	COG1648	precorrin-2 dehydrogenase activity
CXD87_RS14250	COG3468	outer membrane autotransporter barrel domain protein
CXD87_RS14260	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CXD87_RS14265	COG2027	D-alanyl-D-alanine carboxypeptidase
CXD87_RS14270	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CXD87_RS14275	COG0343	queuine tRNA-ribosyltransferase activity
CXD87_RS14280	COG1862	Preprotein translocase
CXD87_RS14285	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CXD87_RS14290	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CXD87_RS14305	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CXD87_RS14310	COG1702	phosphate starvation-inducible protein PhoH
CXD87_RS14315	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CXD87_RS14320	COG4535	Mg2 and Co2 transporter CorC
CXD87_RS14330	COG0667	Aldo Keto reductase
CXD87_RS14355	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CXD87_RS14360	COG0745	RESPONSE REGULATOR receiver
CXD87_RS14365	COG2201	protein-glutamate methylesterase activity
CXD87_RS14375	COG0840	transmembrane signaling receptor activity
CXD87_RS14390	COG0745	RESPONSE REGULATOR receiver
CXD87_RS14425	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CXD87_RS14435	COG0739	heme binding
CXD87_RS14445	COG0521	Mo-molybdopterin cofactor biosynthetic process
CXD87_RS14455	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CXD87_RS14485	COG0625	glutathione transferase activity
CXD87_RS14500	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CXD87_RS14505	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CXD87_RS14510	COG0126	phosphoglycerate kinase activity
CXD87_RS14515	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CXD87_RS14520	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CXD87_RS14525	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CXD87_RS14535	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CXD87_RS14540	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CXD87_RS14545	COG0508	dehydrogenase complex catalyzes the overall conversion of
CXD87_RS14550	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CXD87_RS14560	COG4566	intracellular signal transduction
CXD87_RS14565	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CXD87_RS14570	COG0339	signal peptide processing
CXD87_RS14575	COG1999	signal sequence binding
CXD87_RS14605	COG1187	pseudouridine synthase activity
CXD87_RS14610	COG3161	chorismate lyase activity
CXD87_RS14625	COG0667	Aldo Keto reductase
CXD87_RS14640	COG0335	large ribosomal subunit rRNA binding
CXD87_RS14675	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CXD87_RS14695	COG0450	alkyl hydroperoxide reductase
CXD87_RS14700	COG1960	acyl-CoA dehydrogenase activity
CXD87_RS14715	COG0123	including yeast histone deacetylase and acetoin utilization protein
CXD87_RS14720	COG2951	lytic endotransglycosylase activity
CXD87_RS14735	COG1596	polysaccharide export
CXD87_RS14735	COG1555	photosystem II stabilization
CXD87_RS14740	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CXD87_RS14745	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CXD87_RS14750	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CXD87_RS14770	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CXD87_RS14775	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CXD87_RS14780	COG0287	Prephenate dehydrogenase
CXD87_RS14790	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CXD87_RS14805	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CXD87_RS14815	COG2814	Major facilitator Superfamily
CXD87_RS14845	COG0583	DNA-binding transcription factor activity
CXD87_RS14885	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CXD87_RS14900	COG0667	Aldo Keto reductase
CXD87_RS14910	COG5265	(ABC) transporter
CXD87_RS14960	COG0439	Biotin carboxylase
CXD87_RS14965	COG2188	Transcriptional regulator
CXD87_RS14990	COG0511	ligase activity, forming carbon-carbon bonds
CXD87_RS15000	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CXD87_RS15020	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CXD87_RS15040	COG0500	methyltransferase
CXD87_RS15045	COG5265	(ABC) transporter
CXD87_RS15060	COG0028	Belongs to the TPP enzyme family
CXD87_RS15065	COG0440	acetolactate synthase activity
CXD87_RS15070	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CXD87_RS15075	COG1183	phosphatidylcholine synthase activity
CXD87_RS15090	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CXD87_RS15095	COG1185	polyribonucleotide nucleotidyltransferase activity
CXD87_RS15110	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CXD87_RS15130	COG0149	triose-phosphate isomerase activity
CXD87_RS15135	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CXD87_RS15145	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CXD87_RS15155	COG3799	methylaspartate ammonia-lyase activity
CXD87_RS15190	COG0583	DNA-binding transcription factor activity
CXD87_RS15195	COG0626	cystathionine gamma-synthase activity
CXD87_RS15200	COG3608	succinylglutamate desuccinylase aspartoacylase
CXD87_RS15220	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CXD87_RS15240	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
CXD87_RS15255	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CXD87_RS15260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CXD87_RS15265	COG1733	regulation of RNA biosynthetic process
CXD87_RS15280	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CXD87_RS15285	COG0583	DNA-binding transcription factor activity
CXD87_RS15290	COG1597	lipid kinase activity
CXD87_RS15300	COG0671	phosphoesterase, PA-phosphatase related
CXD87_RS15330	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CXD87_RS15335	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CXD87_RS15340	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CXD87_RS15345	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CXD87_RS15350	COG0649	NAD binding
CXD87_RS15355	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CXD87_RS15365	COG1034	ATP synthesis coupled electron transport
CXD87_RS15370	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CXD87_RS15375	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CXD87_RS15385	COG0713	ATP synthesis coupled electron transport
CXD87_RS15400	COG1007	ATP synthesis coupled electron transport
CXD87_RS15410	COG4774	siderophore transport
CXD87_RS15415	COG4774	siderophore transport
CXD87_RS15430	COG0028	Belongs to the TPP enzyme family
CXD87_RS15435	COG3181	Tripartite tricarboxylate transporter family receptor
CXD87_RS15440	COG0583	DNA-binding transcription factor activity
CXD87_RS15445	COG0560	Phosphoserine phosphatase
CXD87_RS15450	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CXD87_RS15455	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CXD87_RS15460	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CXD87_RS15475	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CXD87_RS15480	COG0308	aminopeptidase N
CXD87_RS15500	COG0028	Belongs to the TPP enzyme family
CXD87_RS15520	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CXD87_RS15530	COG0318	PFAM AMP-dependent synthetase and ligase
CXD87_RS15540	COG1802	Transcriptional regulator
CXD87_RS15550	COG1802	Transcriptional regulator
CXD87_RS15560	COG1028	Short-chain dehydrogenase reductase Sdr
CXD87_RS15580	COG1126	abc transporter atp-binding protein
CXD87_RS15585	COG0765	amino acid transport
CXD87_RS15605	COG1538	Outer membrane efflux protein
CXD87_RS15610	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CXD87_RS15615	COG2274	protein secretion by the type I secretion system
CXD87_RS15620	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CXD87_RS15630	COG2994	toxin metabolic process
CXD87_RS15650	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CXD87_RS15655	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
CXD87_RS15665	COG0583	DNA-binding transcription factor activity
CXD87_RS15675	COG0142	geranyltranstransferase activity
CXD87_RS15685	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CXD87_RS15690	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CXD87_RS15695	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CXD87_RS15700	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CXD87_RS15750	COG3712	iron ion homeostasis
CXD87_RS15755	COG4774	siderophore transport
CXD87_RS15760	COG2353	YceI-like domain
CXD87_RS15775	COG0019	diaminopimelate decarboxylase activity
CXD87_RS15795	COG0747	negative chemotaxis
CXD87_RS15800	COG0601	transmembrane transport
CXD87_RS15805	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CXD87_RS15815	COG0154	amidase activity
CXD87_RS15820	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CXD87_RS15845	COG2154	pterin-4-alpha-carbinolamine dehydratase
CXD87_RS15855	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CXD87_RS15865	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CXD87_RS15870	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CXD87_RS15875	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CXD87_RS15880	COG1929	Belongs to the glycerate kinase type-1 family
CXD87_RS15885	COG0469	pyruvate kinase activity
CXD87_RS15890	COG0700	Nucleoside recognition
CXD87_RS15925	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CXD87_RS15930	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CXD87_RS15945	COG0823	Involved in the tonB-independent uptake of proteins
CXD87_RS15955	COG0848	biopolymer transport protein
CXD87_RS15960	COG0811	peptide transport
CXD87_RS15965	COG0824	Thioesterase
CXD87_RS15970	COG0442	prolyl-tRNA aminoacylation
CXD87_RS15975	COG0494	nUDIX hydrolase
CXD87_RS15990	COG2135	peptidase activity
CXD87_RS16065	COG1196	nuclear chromosome segregation
CXD87_RS16205	COG1464	Belongs to the NlpA lipoprotein family
CXD87_RS16235	COG4211	Belongs to the binding-protein-dependent transport system permease family
CXD87_RS16245	COG0154	amidase activity
CXD87_RS16250	COG0288	reversible hydration of carbon dioxide
CXD87_RS16265	COG0514	ATP-dependent DNA helicase (RecQ)
CXD87_RS16270	COG2255	four-way junction helicase activity
CXD87_RS16285	COG0632	four-way junction helicase activity
CXD87_RS16290	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CXD87_RS16310	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CXD87_RS16320	COG0006	proline dipeptidase activity
CXD87_RS16345	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CXD87_RS16360	COG4783	chaperone-mediated protein folding
CXD87_RS16365	COG0429	hydrolase of the alpha beta-hydrolase fold
CXD87_RS16395	COG0513	Belongs to the DEAD box helicase family
CXD87_RS16415	COG1546	Belongs to the CinA family
CXD87_RS16415	COG1058	Belongs to the CinA family
CXD87_RS16420	COG1414	Transcriptional regulator
CXD87_RS16440	COG0167	dihydroorotate dehydrogenase activity
CXD87_RS16445	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CXD87_RS16460	COG0583	DNA-binding transcription factor activity
CXD87_RS16520	COG0281	malic enzyme
CXD87_RS16520	COG0280	phosphate acetyltransferase
CXD87_RS16530	COG0601	transmembrane transport
CXD87_RS16535	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CXD87_RS16540	COG4172	Belongs to the ABC transporter superfamily
CXD87_RS16570	COG0640	Transcriptional regulator
CXD87_RS16585	COG3135	benzoate transporter
CXD87_RS16590	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CXD87_RS16595	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CXD87_RS16600	COG0742	ribosomal rna small subunit methyltransferase
CXD87_RS16615	COG3639	organic phosphonate transmembrane transporter activity
CXD87_RS16620	COG3639	organic phosphonate transmembrane transporter activity
CXD87_RS16660	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CXD87_RS16665	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CXD87_RS16675	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CXD87_RS16680	COG1058	Belongs to the CinA family
CXD87_RS16680	COG1546	Belongs to the CinA family
CXD87_RS16685	COG0284	orotidine-5'-phosphate decarboxylase activity
CXD87_RS16690	COG1252	NADH dehydrogenase
CXD87_RS16705	COG3468	outer membrane autotransporter barrel domain protein
CXD87_RS16710	COG0459	protein refolding
CXD87_RS16715	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CXD87_RS16735	COG1053	succinate dehydrogenase
CXD87_RS16750	COG0583	DNA-binding transcription factor activity
CXD87_RS16755	COG1053	succinate dehydrogenase
CXD87_RS16780	COG3706	GGDEF domain
CXD87_RS16820	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
CXD87_RS16830	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CXD87_RS16840	COG0069	glutamate synthase activity
CXD87_RS16845	COG2391	methyltransferase activity
CXD87_RS16850	COG0679	Auxin Efflux Carrier
CXD87_RS16875	COG0557	exoribonuclease II activity
CXD87_RS16880	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CXD87_RS16890	COG3128	pkhd-type hydroxylase
CXD87_RS16895	COG0776	regulation of translation
CXD87_RS16925	COG0642	Histidine kinase
CXD87_RS16930	COG3158	transport of potassium into the cell
CXD87_RS16935	COG0137	argininosuccinate synthase activity
CXD87_RS16940	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CXD87_RS16945	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CXD87_RS16955	COG0583	DNA-binding transcription factor activity
CXD87_RS16965	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CXD87_RS16985	COG2186	Transcriptional regulator
CXD87_RS16995	COG2223	nitrite transmembrane transporter activity
CXD87_RS17005	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CXD87_RS17010	COG0450	alkyl hydroperoxide reductase
CXD87_RS17030	COG1214	PFAM Peptidase M22, glycoprotease
CXD87_RS17035	COG1573	uracil-dna glycosylase
CXD87_RS17040	COG0477	Major facilitator Superfamily
CXD87_RS17045	COG1196	nuclear chromosome segregation
CXD87_RS17055	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CXD87_RS17060	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CXD87_RS17075	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CXD87_RS17080	COG1122	ATPase activity
CXD87_RS17085	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CXD87_RS17090	COG1268	BioY protein
CXD87_RS17110	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CXD87_RS17145	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CXD87_RS17150	COG2878	Part of a membrane complex involved in electron transport
CXD87_RS17165	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CXD87_RS17170	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CXD87_RS17175	COG0251	oxidation-reduction process
CXD87_RS17185	COG3228	Belongs to the MtfA family
CXD87_RS17190	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CXD87_RS17200	COG0133	tryptophan synthase activity
CXD87_RS17205	COG0159	tryptophan synthase activity
CXD87_RS17210	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CXD87_RS17230	COG1530	ribonuclease E activity
CXD87_RS17240	COG0546	phosphoglycolate phosphatase activity
CXD87_RS17245	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CXD87_RS17250	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CXD87_RS17265	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CXD87_RS17270	COG0583	DNA-binding transcription factor activity
CXD87_RS17280	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CXD87_RS17300	COG0251	oxidation-reduction process
CXD87_RS17305	COG1017	nitric oxide dioxygenase activity
CXD87_RS17305	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CXD87_RS17310	COG2031	fatty acid transporter
CXD87_RS17315	COG1012	belongs to the aldehyde dehydrogenase family
CXD87_RS17320	COG1802	Transcriptional regulator
CXD87_RS17330	COG1278	Cold shock
CXD87_RS17335	COG0583	DNA-binding transcription factor activity
CXD87_RS17360	COG0183	Belongs to the thiolase family
CXD87_RS17370	COG1960	acyl-CoA dehydrogenase activity
CXD87_RS17375	COG0583	DNA-binding transcription factor activity
CXD87_RS17380	COG3181	Tripartite tricarboxylate transporter family receptor
CXD87_RS17385	COG1024	Enoyl-CoA hydratase
CXD87_RS17390	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CXD87_RS17395	COG1253	flavin adenine dinucleotide binding
CXD87_RS17400	COG1285	pathogenesis
CXD87_RS17410	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CXD87_RS17425	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CXD87_RS17440	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CXD87_RS17450	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CXD87_RS17455	COG3181	Tripartite tricarboxylate transporter family receptor
CXD87_RS17460	COG1960	acyl-CoA dehydrogenase activity
CXD87_RS17480	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CXD87_RS17485	COG1024	Enoyl-CoA hydratase
CXD87_RS17490	COG1960	acyl-CoA dehydrogenase activity
CXD87_RS17510	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CXD87_RS17515	COG0022	dehydrogenase e1 component
CXD87_RS17520	COG1024	Enoyl-CoA hydratase
CXD87_RS17525	COG0508	dehydrogenase complex catalyzes the overall conversion of
CXD87_RS17545	COG0683	leucine binding
CXD87_RS17550	COG0559	Belongs to the binding-protein-dependent transport system permease family
CXD87_RS17555	COG0411	ABC transporter
CXD87_RS17565	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CXD87_RS17580	COG3181	Tripartite tricarboxylate transporter family receptor
CXD87_RS17605	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CXD87_RS17610	COG0793	Belongs to the peptidase S41A family
CXD87_RS17615	COG4942	peptidase
CXD87_RS17620	COG0588	phosphoglycerate mutase activity
CXD87_RS17625	COG1054	Belongs to the UPF0176 family
CXD87_RS17630	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CXD87_RS17635	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CXD87_RS17640	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CXD87_RS17645	COG3181	Tripartite tricarboxylate transporter family receptor
CXD87_RS17660	COG2226	methyltransferase
CXD87_RS17665	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CXD87_RS17680	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CXD87_RS17685	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CXD87_RS17710	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CXD87_RS17735	COG1335	isochorismatase
CXD87_RS17740	COG2309	aminopeptidase activity
CXD87_RS17750	COG3473	Maleate cis-trans isomerase
CXD87_RS17760	COG2068	MobA-Related Protein
CXD87_RS17785	COG2204	response regulator
CXD87_RS17790	COG5000	phosphorelay sensor kinase activity
CXD87_RS17800	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CXD87_RS17800	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CXD87_RS17810	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
CXD87_RS17845	COG0583	DNA-binding transcription factor activity
CXD87_RS17865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CXD87_RS17870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXD87_RS17885	COG0758	DNA mediated transformation
CXD87_RS17890	COG1522	sequence-specific DNA binding
CXD87_RS17900	COG0242	peptide deformylase activity
CXD87_RS17915	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CXD87_RS17925	COG0546	phosphoglycolate phosphatase activity
CXD87_RS17945	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CXD87_RS17950	COG1942	4-Oxalocrotonate Tautomerase
CXD87_RS17955	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CXD87_RS17980	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CXD87_RS18000	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CXD87_RS18005	COG1024	Enoyl-CoA hydratase
CXD87_RS18010	COG1414	Transcriptional regulator
CXD87_RS18015	COG0318	PFAM AMP-dependent synthetase and ligase
CXD87_RS18020	COG3181	Tripartite tricarboxylate transporter family receptor
CXD87_RS18065	COG3422	double-strand break repair
CXD87_RS18070	COG0330	HflC and HflK could
CXD87_RS18080	COG0251	oxidation-reduction process
CXD87_RS18130	COG3723	Recombinational DNA repair protein, rece pathway
CXD87_RS18165	COG0582	viral genome integration into host DNA
CXD87_RS18200	COG0706	membrane insertase activity
CXD87_RS18205	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CXD87_RS18210	COG0594	ribonuclease P activity
CXD87_RS18215	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CXD87_RS18220	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CXD87_RS18235	COG1414	Transcriptional regulator
CXD87_RS18240	COG0154	amidase activity
CXD87_RS18255	COG1304	FMN binding
CXD87_RS18305	COG0183	Belongs to the thiolase family
CXD87_RS18310	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CXD87_RS18325	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CXD87_RS18330	COG3181	Tripartite tricarboxylate transporter family receptor
CXD87_RS18340	COG2358	TRAP transporter, solute receptor (TAXI family
CXD87_RS18350	COG1629	transport
CXD87_RS18355	COG2922	Belongs to the Smg family
CXD87_RS18380	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CXD87_RS18385	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CXD87_RS18390	COG1028	Short-chain dehydrogenase reductase Sdr
CXD87_RS18395	COG1012	belongs to the aldehyde dehydrogenase family
CXD87_RS18405	COG0028	Belongs to the TPP enzyme family
CXD87_RS18410	COG1522	sequence-specific DNA binding
CXD87_RS18415	COG3781	membrane
CXD87_RS18425	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CXD87_RS18445	COG4206	TonB-dependent receptor
CXD87_RS18450	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CXD87_RS18455	COG2022	thiamine diphosphate biosynthetic process
CXD87_RS18460	COG0351	phosphomethylpyrimidine kinase
CXD87_RS18465	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CXD87_RS18480	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CXD87_RS18490	COG0628	permease
CXD87_RS18500	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CXD87_RS18515	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CXD87_RS18520	COG0049	tRNA binding
CXD87_RS18525	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CXD87_RS18530	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CXD87_RS18535	COG0051	transcription antitermination factor activity, RNA binding
CXD87_RS18540	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CXD87_RS18545	COG0088	Forms part of the polypeptide exit tunnel
CXD87_RS18550	COG0089	rRNA binding
CXD87_RS18555	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CXD87_RS18560	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CXD87_RS18565	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CXD87_RS18570	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CXD87_RS18575	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CXD87_RS18580	COG0255	Belongs to the universal ribosomal protein uL29 family
CXD87_RS18585	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CXD87_RS18605	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CXD87_RS18610	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CXD87_RS18615	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CXD87_RS18620	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CXD87_RS18625	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CXD87_RS18630	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CXD87_RS18635	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CXD87_RS18640	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CXD87_RS18645	COG1841	ribosomal large subunit assembly
CXD87_RS18650	COG0200	Binds to the 23S rRNA
CXD87_RS18655	COG0201	protein transport
CXD87_RS18660	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CXD87_RS18665	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CXD87_RS18670	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CXD87_RS18675	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CXD87_RS18680	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CXD87_RS18685	COG0202	RNA polymerase activity
CXD87_RS18690	COG0203	ribosomal protein L17
CXD87_RS18695	COG0537	adenosine 5'-monophosphoramidase activity
CXD87_RS18700	COG1324	tolerance protein
CXD87_RS18705	COG4232	protein-disulfide reductase activity
CXD87_RS18720	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CXD87_RS18730	COG1333	cytochrome c biogenesis protein
CXD87_RS18735	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CXD87_RS18750	COG1965	Belongs to the frataxin family
CXD87_RS18760	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CXD87_RS18765	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CXD87_RS18770	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CXD87_RS18785	COG2814	Major facilitator Superfamily
CXD87_RS18790	COG0629	single-stranded DNA binding
CXD87_RS18830	COG0402	S-adenosylhomocysteine deaminase activity
CXD87_RS18840	COG0438	transferase activity, transferring glycosyl groups
CXD87_RS18860	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CXD87_RS18885	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CXD87_RS18910	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CXD87_RS18915	COG1956	GAF domain-containing protein
CXD87_RS18920	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CXD87_RS18935	COG1652	LysM domain
CXD87_RS18950	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CXD87_RS18965	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CXD87_RS18995	COG3181	Tripartite tricarboxylate transporter family receptor
CXD87_RS19010	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CXD87_RS19025	COG1024	Enoyl-CoA hydratase
CXD87_RS19040	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CXD87_RS19045	COG1309	transcriptional regulator
CXD87_RS19050	COG2816	NAD+ diphosphatase activity
CXD87_RS19055	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CXD87_RS19140	COG2814	Major facilitator Superfamily
CXD87_RS19145	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CXD87_RS19165	COG1999	signal sequence binding
CXD87_RS19170	COG0109	protoheme IX farnesyltransferase activity
CXD87_RS19210	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CXD87_RS19230	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CXD87_RS19235	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CXD87_RS19245	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CXD87_RS19250	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CXD87_RS19260	COG0067	glutamate synthase
CXD87_RS19260	COG0069	glutamate synthase activity
CXD87_RS19260	COG0070	glutamate synthase
CXD87_RS19270	COG3047	cAMP biosynthetic process
CXD87_RS19280	COG1127	ABC transporter
CXD87_RS19285	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CXD87_RS19290	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CXD87_RS19295	COG2853	Lipoprotein
CXD87_RS19310	COG0842	Transport permease protein
CXD87_RS19320	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CXD87_RS19325	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CXD87_RS19330	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CXD87_RS19335	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CXD87_RS19340	COG0131	Imidazoleglycerol-phosphate dehydratase
CXD87_RS19345	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CXD87_RS19350	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CXD87_RS19355	COG0107	imidazoleglycerol-phosphate synthase activity
CXD87_RS19360	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CXD87_RS19365	COG0140	phosphoribosyl-ATP diphosphatase activity
CXD87_RS19370	COG0537	adenosine 5'-monophosphoramidase activity
CXD87_RS19375	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CXD87_RS19380	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CXD87_RS19395	COG3181	Tripartite tricarboxylate transporter family receptor
CXD87_RS19430	COG3702	type iv secretory pathway
CXD87_RS19435	COG3451	type IV secretory pathway VirB4
CXD87_RS19450	COG3736	Type IV secretory pathway, component VirB8
CXD87_RS19455	COG3504	Conjugal transfer protein
CXD87_RS19460	COG2948	multi-organism process
CXD87_RS19465	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
CXD87_RS19475	COG0697	spore germination
CXD87_RS19495	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CXD87_RS19500	COG0747	negative chemotaxis
CXD87_RS19505	COG0601	transmembrane transport
CXD87_RS19510	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CXD87_RS19525	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CXD87_RS19535	COG0494	nUDIX hydrolase
CXD87_RS19575	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
CXD87_RS19580	COG0237	dephospho-CoA kinase activity
CXD87_RS19585	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CXD87_RS19600	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CXD87_RS19605	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CXD87_RS19615	COG0477	Major facilitator Superfamily
CXD87_RS19620	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CXD87_RS19635	COG1126	abc transporter atp-binding protein
CXD87_RS19640	COG0765	amino acid transport
CXD87_RS19645	COG4597	amino acid ABC transporter
CXD87_RS19650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXD87_RS19655	COG2884	Cell division ATP-binding protein ftsE
CXD87_RS19660	COG2177	Part of the ABC transporter FtsEX involved in
CXD87_RS19665	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CXD87_RS19675	COG1194	a g-specific adenine glycosylase
CXD87_RS19685	COG2226	methyltransferase
CXD87_RS19695	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CXD87_RS19700	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CXD87_RS19715	COG1024	Enoyl-CoA hydratase
CXD87_RS19735	COG1024	Enoyl-CoA hydratase
CXD87_RS19740	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CXD87_RS19755	COG0753	catalase activity
CXD87_RS19760	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CXD87_RS19765	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CXD87_RS19775	COG2175	clavaminate synthase activity
CXD87_RS19780	COG1473	amidohydrolase
CXD87_RS19785	COG4608	Belongs to the ABC transporter superfamily
CXD87_RS19790	COG0444	Belongs to the ABC transporter superfamily
CXD87_RS19805	COG0747	negative chemotaxis
CXD87_RS19810	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CXD87_RS19845	COG0436	Aminotransferase
CXD87_RS19850	COG1278	Cold shock