locus-tag	class	description
WU27_RS00005	COG0445	tRNA wobble uridine modification
WU27_RS00010	COG0357	Ribosomal RNA small subunit methyltransferase G
WU27_RS00015	COG1192	Involved in chromosome partitioning
WU27_RS00025	COG1475	DNA binding
WU27_RS00030	COG0252	asparaginase activity
WU27_RS00055	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
WU27_RS00065	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
WU27_RS00075	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
WU27_RS00080	COG0081	regulation of translation
WU27_RS00085	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
WU27_RS00090	COG0222	ribosome binding
WU27_RS00095	COG0085	RNA polymerase activity
WU27_RS00100	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
WU27_RS00140	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU27_RS00165	COG1024	Enoyl-CoA hydratase
WU27_RS00185	COG0752	glycyl-tRNA synthetase alpha subunit
WU27_RS00190	COG0751	glycine-tRNA ligase activity
WU27_RS00195	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
WU27_RS00200	COG0204	Acyl-transferase
WU27_RS00215	COG0242	peptide deformylase activity
WU27_RS00250	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
WU27_RS00255	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
WU27_RS00260	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
WU27_RS00260	COG2813	Specifically methylates the guanine in position
WU27_RS00275	COG2223	nitrite transmembrane transporter activity
WU27_RS00285	COG1794	racemase activity, acting on amino acids and derivatives
WU27_RS00290	COG1126	abc transporter atp-binding protein
WU27_RS00295	COG0765	amino acid transport
WU27_RS00300	COG0765	amino acid transport
WU27_RS00305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WU27_RS00370	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
WU27_RS00385	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WU27_RS00390	COG1956	GAF domain-containing protein
WU27_RS00395	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WU27_RS00415	COG2186	Transcriptional regulator
WU27_RS00420	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
WU27_RS00445	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WU27_RS00465	COG0438	transferase activity, transferring glycosyl groups
WU27_RS00475	COG0402	S-adenosylhomocysteine deaminase activity
WU27_RS00515	COG0629	single-stranded DNA binding
WU27_RS00520	COG2814	Major facilitator Superfamily
WU27_RS00535	COG0232	Belongs to the dGTPase family. Type 2 subfamily
WU27_RS00540	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
WU27_RS00545	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
WU27_RS00555	COG1965	Belongs to the frataxin family
WU27_RS00570	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
WU27_RS00575	COG1333	cytochrome c biogenesis protein
WU27_RS00585	COG0218	Necessary for normal cell division and for the maintenance of normal septation
WU27_RS00600	COG4232	protein-disulfide reductase activity
WU27_RS00605	COG1324	tolerance protein
WU27_RS00610	COG0537	adenosine 5'-monophosphoramidase activity
WU27_RS00615	COG0203	ribosomal protein L17
WU27_RS00620	COG0202	RNA polymerase activity
WU27_RS00625	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
WU27_RS00630	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
WU27_RS00635	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
WU27_RS00640	COG0257	Belongs to the bacterial ribosomal protein bL36 family
WU27_RS00645	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
WU27_RS00650	COG0201	protein transport
WU27_RS00655	COG0200	Binds to the 23S rRNA
WU27_RS00660	COG1841	ribosomal large subunit assembly
WU27_RS00665	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
WU27_RS00670	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
WU27_RS00675	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
WU27_RS00680	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
WU27_RS00685	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
WU27_RS00690	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
WU27_RS00695	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
WU27_RS00700	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
WU27_RS00720	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
WU27_RS00725	COG0255	Belongs to the universal ribosomal protein uL29 family
WU27_RS00730	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
WU27_RS00735	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
WU27_RS00740	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
WU27_RS00745	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
WU27_RS00750	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
WU27_RS00755	COG0089	rRNA binding
WU27_RS00760	COG0088	Forms part of the polypeptide exit tunnel
WU27_RS00765	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
WU27_RS00770	COG0051	transcription antitermination factor activity, RNA binding
WU27_RS00775	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
WU27_RS00780	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
WU27_RS00785	COG0049	tRNA binding
WU27_RS00790	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
WU27_RS00800	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
WU27_RS00810	COG0628	permease
WU27_RS00820	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
WU27_RS00830	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
WU27_RS00835	COG0351	phosphomethylpyrimidine kinase
WU27_RS00840	COG2022	thiamine diphosphate biosynthetic process
WU27_RS00845	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
WU27_RS00850	COG4206	TonB-dependent receptor
WU27_RS00870	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
WU27_RS00880	COG3781	membrane
WU27_RS00885	COG1522	sequence-specific DNA binding
WU27_RS00890	COG0028	Belongs to the TPP enzyme family
WU27_RS00900	COG1012	belongs to the aldehyde dehydrogenase family
WU27_RS00905	COG1028	Short-chain dehydrogenase reductase Sdr
WU27_RS00910	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WU27_RS00915	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
WU27_RS00940	COG2922	Belongs to the Smg family
WU27_RS00945	COG1629	transport
WU27_RS00955	COG2358	TRAP transporter, solute receptor (TAXI family
WU27_RS00965	COG3181	Tripartite tricarboxylate transporter family receptor
WU27_RS00970	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
WU27_RS00985	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
WU27_RS01000	COG1960	acyl-CoA dehydrogenase activity
WU27_RS01020	COG1960	acyl-CoA dehydrogenase activity
WU27_RS01040	COG1304	FMN binding
WU27_RS01055	COG0154	amidase activity
WU27_RS01060	COG1414	Transcriptional regulator
WU27_RS01075	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
WU27_RS01080	COG0230	Belongs to the bacterial ribosomal protein bL34 family
WU27_RS01085	COG0594	ribonuclease P activity
WU27_RS01090	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
WU27_RS01095	COG0706	membrane insertase activity
WU27_RS01105	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
WU27_RS01130	COG0582	viral genome integration into host DNA
WU27_RS01165	COG3723	Recombinational DNA repair protein, rece pathway
WU27_RS01210	COG0251	oxidation-reduction process
WU27_RS01220	COG0330	HflC and HflK could
WU27_RS01225	COG3422	double-strand break repair
WU27_RS01240	COG0583	DNA-binding transcription factor activity
WU27_RS01270	COG3181	Tripartite tricarboxylate transporter family receptor
WU27_RS01275	COG0318	PFAM AMP-dependent synthetase and ligase
WU27_RS01280	COG1414	Transcriptional regulator
WU27_RS01285	COG1024	Enoyl-CoA hydratase
WU27_RS01290	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WU27_RS01310	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
WU27_RS01330	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WU27_RS01335	COG1942	4-Oxalocrotonate Tautomerase
WU27_RS01340	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
WU27_RS01360	COG0546	phosphoglycolate phosphatase activity
WU27_RS01370	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
WU27_RS01385	COG0242	peptide deformylase activity
WU27_RS01395	COG1522	sequence-specific DNA binding
WU27_RS01400	COG0758	DNA mediated transformation
WU27_RS01415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WU27_RS01420	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WU27_RS01425	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
WU27_RS01440	COG0583	DNA-binding transcription factor activity
WU27_RS01465	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
WU27_RS01475	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
WU27_RS01475	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
WU27_RS01485	COG5000	phosphorelay sensor kinase activity
WU27_RS01490	COG2204	response regulator
WU27_RS01515	COG2068	MobA-Related Protein
WU27_RS01525	COG3473	Maleate cis-trans isomerase
WU27_RS01530	COG0596	Alpha beta hydrolase
WU27_RS01535	COG2309	aminopeptidase activity
WU27_RS01540	COG1335	isochorismatase
WU27_RS01565	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
WU27_RS01590	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
WU27_RS01595	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WU27_RS01610	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
WU27_RS01615	COG2226	methyltransferase
WU27_RS01630	COG3181	Tripartite tricarboxylate transporter family receptor
WU27_RS01635	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
WU27_RS01640	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
WU27_RS01645	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
WU27_RS01650	COG1054	Belongs to the UPF0176 family
WU27_RS01655	COG0588	phosphoglycerate mutase activity
WU27_RS01660	COG4942	peptidase
WU27_RS01665	COG0793	Belongs to the peptidase S41A family
WU27_RS01670	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
WU27_RS01695	COG3181	Tripartite tricarboxylate transporter family receptor
WU27_RS01710	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WU27_RS01720	COG0411	ABC transporter
WU27_RS01725	COG0559	Belongs to the binding-protein-dependent transport system permease family
WU27_RS01730	COG0683	leucine binding
WU27_RS01750	COG0508	dehydrogenase complex catalyzes the overall conversion of
WU27_RS01755	COG1024	Enoyl-CoA hydratase
WU27_RS01760	COG0022	dehydrogenase e1 component
WU27_RS01765	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
WU27_RS01785	COG1960	acyl-CoA dehydrogenase activity
WU27_RS01790	COG1024	Enoyl-CoA hydratase
WU27_RS01795	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
WU27_RS01815	COG1960	acyl-CoA dehydrogenase activity
WU27_RS01820	COG3181	Tripartite tricarboxylate transporter family receptor
WU27_RS01825	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU27_RS01835	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WU27_RS01845	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
WU27_RS01860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WU27_RS01870	COG1285	pathogenesis
WU27_RS01875	COG1253	flavin adenine dinucleotide binding
WU27_RS01880	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU27_RS01885	COG1024	Enoyl-CoA hydratase
WU27_RS01890	COG3181	Tripartite tricarboxylate transporter family receptor
WU27_RS01895	COG0583	DNA-binding transcription factor activity
WU27_RS01900	COG1960	acyl-CoA dehydrogenase activity
WU27_RS01910	COG0183	Belongs to the thiolase family
WU27_RS01925	COG0583	DNA-binding transcription factor activity
WU27_RS01930	COG1278	Cold shock
WU27_RS01940	COG1802	Transcriptional regulator
WU27_RS01945	COG1012	belongs to the aldehyde dehydrogenase family
WU27_RS01950	COG2031	fatty acid transporter
WU27_RS01955	COG1017	nitric oxide dioxygenase activity
WU27_RS01955	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WU27_RS01960	COG0251	oxidation-reduction process
WU27_RS01980	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU27_RS01990	COG0583	DNA-binding transcription factor activity
WU27_RS01995	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU27_RS02005	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
WU27_RS02010	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
WU27_RS02015	COG0546	phosphoglycolate phosphatase activity
WU27_RS02025	COG1530	ribonuclease E activity
WU27_RS02040	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
WU27_RS02045	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
WU27_RS02050	COG0159	tryptophan synthase activity
WU27_RS02055	COG0133	tryptophan synthase activity
WU27_RS02065	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
WU27_RS02070	COG3228	Belongs to the MtfA family
WU27_RS02080	COG0251	oxidation-reduction process
WU27_RS02085	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
WU27_RS02090	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
WU27_RS02105	COG2878	Part of a membrane complex involved in electron transport
WU27_RS02110	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
WU27_RS02145	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
WU27_RS02165	COG1268	BioY protein
WU27_RS02170	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
WU27_RS02175	COG1122	ATPase activity
WU27_RS02180	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
WU27_RS02195	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
WU27_RS02200	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
WU27_RS02210	COG1196	nuclear chromosome segregation
WU27_RS02215	COG0477	Major facilitator Superfamily
WU27_RS02220	COG1573	uracil-dna glycosylase
WU27_RS02225	COG1214	PFAM Peptidase M22, glycoprotease
WU27_RS02250	COG0450	alkyl hydroperoxide reductase
WU27_RS02255	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WU27_RS02265	COG2223	nitrite transmembrane transporter activity
WU27_RS02275	COG2186	Transcriptional regulator
WU27_RS02295	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
WU27_RS02305	COG0583	DNA-binding transcription factor activity
WU27_RS02315	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
WU27_RS02320	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
WU27_RS02325	COG0137	argininosuccinate synthase activity
WU27_RS02330	COG3158	transport of potassium into the cell
WU27_RS02335	COG0642	Histidine kinase
WU27_RS02365	COG0776	regulation of translation
WU27_RS02370	COG3128	pkhd-type hydroxylase
WU27_RS02380	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
WU27_RS02385	COG0557	exoribonuclease II activity
WU27_RS02410	COG0679	Auxin Efflux Carrier
WU27_RS02415	COG2391	methyltransferase activity
WU27_RS02420	COG0069	glutamate synthase activity
WU27_RS02430	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WU27_RS02440	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
WU27_RS02445	COG1262	PFAM Formylglycine-generating sulfatase enzyme
WU27_RS02480	COG3706	GGDEF domain
WU27_RS02500	COG1053	succinate dehydrogenase
WU27_RS02505	COG0583	DNA-binding transcription factor activity
WU27_RS02515	COG1053	succinate dehydrogenase
WU27_RS02535	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
WU27_RS02540	COG0459	protein refolding
WU27_RS02545	COG3468	outer membrane autotransporter barrel domain protein
WU27_RS02560	COG1252	NADH dehydrogenase
WU27_RS02565	COG0284	orotidine-5'-phosphate decarboxylase activity
WU27_RS02570	COG1546	Belongs to the CinA family
WU27_RS02570	COG1058	Belongs to the CinA family
WU27_RS02575	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
WU27_RS02585	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
WU27_RS02590	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
WU27_RS02625	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
WU27_RS02630	COG3639	organic phosphonate transmembrane transporter activity
WU27_RS02635	COG3639	organic phosphonate transmembrane transporter activity
WU27_RS02655	COG0742	ribosomal rna small subunit methyltransferase
WU27_RS02660	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
WU27_RS02665	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
WU27_RS02670	COG3135	benzoate transporter
WU27_RS02685	COG0640	Transcriptional regulator
WU27_RS02715	COG4172	Belongs to the ABC transporter superfamily
WU27_RS02720	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WU27_RS02725	COG0601	transmembrane transport
WU27_RS02735	COG0280	phosphate acetyltransferase
WU27_RS02735	COG0281	malic enzyme
WU27_RS02795	COG0583	DNA-binding transcription factor activity
WU27_RS02805	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
WU27_RS02810	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
WU27_RS02815	COG0167	dihydroorotate dehydrogenase activity
WU27_RS02835	COG1414	Transcriptional regulator
WU27_RS02840	COG1058	Belongs to the CinA family
WU27_RS02840	COG1546	Belongs to the CinA family
WU27_RS02860	COG0513	Belongs to the DEAD box helicase family
WU27_RS02890	COG0429	hydrolase of the alpha beta-hydrolase fold
WU27_RS02895	COG4783	chaperone-mediated protein folding
WU27_RS02910	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WU27_RS02935	COG0006	proline dipeptidase activity
WU27_RS02945	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WU27_RS02965	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
WU27_RS02970	COG0632	four-way junction helicase activity
WU27_RS02985	COG2255	four-way junction helicase activity
WU27_RS02990	COG0514	ATP-dependent DNA helicase (RecQ)
WU27_RS03005	COG0288	reversible hydration of carbon dioxide
WU27_RS03010	COG0154	amidase activity
WU27_RS03020	COG4211	Belongs to the binding-protein-dependent transport system permease family
WU27_RS03050	COG1464	Belongs to the NlpA lipoprotein family
WU27_RS03195	COG1196	nuclear chromosome segregation
WU27_RS03265	COG2135	peptidase activity
WU27_RS03280	COG0494	nUDIX hydrolase
WU27_RS03285	COG0442	prolyl-tRNA aminoacylation
WU27_RS03290	COG0824	Thioesterase
WU27_RS03295	COG0811	peptide transport
WU27_RS03300	COG0848	biopolymer transport protein
WU27_RS03310	COG0823	Involved in the tonB-independent uptake of proteins
WU27_RS03325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WU27_RS03330	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
WU27_RS03365	COG0700	Nucleoside recognition
WU27_RS03370	COG0469	pyruvate kinase activity
WU27_RS03375	COG1929	Belongs to the glycerate kinase type-1 family
WU27_RS03380	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
WU27_RS03385	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
WU27_RS03390	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
WU27_RS03400	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
WU27_RS03410	COG2154	pterin-4-alpha-carbinolamine dehydratase
WU27_RS03435	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
WU27_RS03440	COG0154	amidase activity
WU27_RS03450	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WU27_RS03455	COG0601	transmembrane transport
WU27_RS03460	COG0747	negative chemotaxis
WU27_RS03480	COG0019	diaminopimelate decarboxylase activity
WU27_RS03495	COG2353	YceI-like domain
WU27_RS03500	COG4774	siderophore transport
WU27_RS03505	COG3712	iron ion homeostasis
WU27_RS03545	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
WU27_RS03550	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
WU27_RS03555	COG0211	Belongs to the bacterial ribosomal protein bL27 family
WU27_RS03560	COG0261	This protein binds to 23S rRNA in the presence of protein L20
WU27_RS03570	COG0142	geranyltranstransferase activity
WU27_RS03580	COG0583	DNA-binding transcription factor activity
WU27_RS03590	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
WU27_RS03595	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WU27_RS03610	COG2994	toxin metabolic process
WU27_RS03620	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
WU27_RS03625	COG2274	protein secretion by the type I secretion system
WU27_RS03630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WU27_RS03635	COG1538	Outer membrane efflux protein
WU27_RS03650	COG0765	amino acid transport
WU27_RS03655	COG0765	amino acid transport
WU27_RS03660	COG1126	abc transporter atp-binding protein
WU27_RS03680	COG1028	Short-chain dehydrogenase reductase Sdr
WU27_RS03690	COG1802	Transcriptional regulator
WU27_RS03700	COG1802	Transcriptional regulator
WU27_RS03710	COG0318	PFAM AMP-dependent synthetase and ligase
WU27_RS03720	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WU27_RS03740	COG0028	Belongs to the TPP enzyme family
WU27_RS03760	COG0308	aminopeptidase N
WU27_RS03765	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
WU27_RS03780	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
WU27_RS03785	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
WU27_RS03790	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
WU27_RS03795	COG0560	Phosphoserine phosphatase
WU27_RS03800	COG0583	DNA-binding transcription factor activity
WU27_RS03805	COG3181	Tripartite tricarboxylate transporter family receptor
WU27_RS03810	COG0028	Belongs to the TPP enzyme family
WU27_RS03825	COG4774	siderophore transport
WU27_RS03830	COG4774	siderophore transport
WU27_RS03840	COG1007	ATP synthesis coupled electron transport
WU27_RS03855	COG0713	ATP synthesis coupled electron transport
WU27_RS03865	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WU27_RS03870	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
WU27_RS03875	COG1034	ATP synthesis coupled electron transport
WU27_RS03885	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
WU27_RS03890	COG0649	NAD binding
WU27_RS03895	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WU27_RS03900	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WU27_RS03905	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WU27_RS03910	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WU27_RS03940	COG0671	phosphoesterase, PA-phosphatase related
WU27_RS03950	COG1597	lipid kinase activity
WU27_RS03955	COG0583	DNA-binding transcription factor activity
WU27_RS03960	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
WU27_RS03970	COG1733	regulation of RNA biosynthetic process
WU27_RS03975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WU27_RS03980	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WU27_RS03995	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
WU27_RS04015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WU27_RS04035	COG3608	succinylglutamate desuccinylase aspartoacylase
WU27_RS04040	COG0626	cystathionine gamma-synthase activity
WU27_RS04045	COG0583	DNA-binding transcription factor activity
WU27_RS04080	COG3799	methylaspartate ammonia-lyase activity
WU27_RS04090	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
WU27_RS04100	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
WU27_RS04105	COG0149	triose-phosphate isomerase activity
WU27_RS04125	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
WU27_RS04140	COG1185	polyribonucleotide nucleotidyltransferase activity
WU27_RS04145	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
WU27_RS04160	COG1183	phosphatidylcholine synthase activity
WU27_RS04165	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
WU27_RS04170	COG0440	acetolactate synthase activity
WU27_RS04175	COG0028	Belongs to the TPP enzyme family
WU27_RS04190	COG5265	(ABC) transporter
WU27_RS04195	COG0500	methyltransferase
WU27_RS04215	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
WU27_RS04235	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
WU27_RS04245	COG0511	ligase activity, forming carbon-carbon bonds
WU27_RS04270	COG2188	Transcriptional regulator
WU27_RS04275	COG0439	Biotin carboxylase
WU27_RS04280	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
WU27_RS04325	COG5265	(ABC) transporter
WU27_RS04335	COG0667	Aldo Keto reductase
WU27_RS04350	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
WU27_RS04390	COG0583	DNA-binding transcription factor activity
WU27_RS04415	COG2814	Major facilitator Superfamily
WU27_RS04425	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
WU27_RS04440	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
WU27_RS04450	COG0287	Prephenate dehydrogenase
WU27_RS04455	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
WU27_RS04460	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
WU27_RS04480	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
WU27_RS04485	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
WU27_RS04490	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WU27_RS04495	COG1555	photosystem II stabilization
WU27_RS04495	COG1596	polysaccharide export
WU27_RS04510	COG2951	lytic endotransglycosylase activity
WU27_RS04515	COG0123	including yeast histone deacetylase and acetoin utilization protein
WU27_RS04530	COG1960	acyl-CoA dehydrogenase activity
WU27_RS04535	COG0450	alkyl hydroperoxide reductase
WU27_RS04550	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
WU27_RS04555	COG4208	sulfate ABC transporter
WU27_RS04560	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
WU27_RS04590	COG0335	large ribosomal subunit rRNA binding
WU27_RS04605	COG0667	Aldo Keto reductase
WU27_RS04615	COG2814	Major facilitator Superfamily
WU27_RS04620	COG3161	chorismate lyase activity
WU27_RS04625	COG1187	pseudouridine synthase activity
WU27_RS04635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WU27_RS04655	COG1999	signal sequence binding
WU27_RS04660	COG0339	signal peptide processing
WU27_RS04665	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
WU27_RS04670	COG4566	intracellular signal transduction
WU27_RS04680	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
WU27_RS04685	COG0508	dehydrogenase complex catalyzes the overall conversion of
WU27_RS04690	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WU27_RS04695	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
WU27_RS04705	COG1385	rRNA (uridine-N3-)-methyltransferase activity
WU27_RS04710	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
WU27_RS04715	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
WU27_RS04720	COG0126	phosphoglycerate kinase activity
WU27_RS04725	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
WU27_RS04730	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
WU27_RS04745	COG0625	glutathione transferase activity
WU27_RS04780	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
WU27_RS04790	COG0521	Mo-molybdopterin cofactor biosynthetic process
WU27_RS04800	COG0739	heme binding
WU27_RS04810	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
WU27_RS04845	COG0745	RESPONSE REGULATOR receiver
WU27_RS04860	COG0840	transmembrane signaling receptor activity
WU27_RS04870	COG2201	protein-glutamate methylesterase activity
WU27_RS04875	COG0745	RESPONSE REGULATOR receiver
WU27_RS04880	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
WU27_RS04905	COG0667	Aldo Keto reductase
WU27_RS04915	COG4535	Mg2 and Co2 transporter CorC
WU27_RS04920	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
WU27_RS04925	COG1702	phosphate starvation-inducible protein PhoH
WU27_RS04930	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
WU27_RS04945	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WU27_RS04950	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WU27_RS04955	COG1862	Preprotein translocase
WU27_RS04960	COG0343	queuine tRNA-ribosyltransferase activity
WU27_RS04965	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
WU27_RS04970	COG2027	D-alanyl-D-alanine carboxypeptidase
WU27_RS04975	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
WU27_RS04985	COG3468	outer membrane autotransporter barrel domain protein
WU27_RS04990	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
WU27_RS04990	COG1648	precorrin-2 dehydrogenase activity
WU27_RS05015	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
WU27_RS05020	COG0741	lytic transglycosylase activity
WU27_RS05025	COG0436	Aminotransferase
WU27_RS05035	COG0280	phosphate acetyltransferase
WU27_RS05035	COG0281	malic enzyme
WU27_RS05045	COG2732	(Barnase) inhibitor
WU27_RS05060	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
WU27_RS05085	COG0248	Ppx GppA phosphatase
WU27_RS05095	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
WU27_RS05105	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
WU27_RS05110	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
WU27_RS05115	COG1534	Rna-binding protein
WU27_RS05145	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
WU27_RS05160	COG1295	ribonuclease BN
WU27_RS05170	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
WU27_RS05175	COG0745	RESPONSE REGULATOR receiver
WU27_RS05180	COG2205	protein histidine kinase activity
WU27_RS05215	COG1022	Amp-dependent synthetase and ligase
WU27_RS05230	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
WU27_RS05235	COG1028	Short-chain dehydrogenase reductase Sdr
WU27_RS05245	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
WU27_RS05260	COG1136	(ABC) transporter
WU27_RS05265	COG0084	hydrolase, TatD family'
WU27_RS05295	COG0658	competence protein
WU27_RS05295	COG2333	competence protein COMEC
WU27_RS05305	COG0613	PHP domain protein
WU27_RS05320	COG3539	Fimbrial protein
WU27_RS05325	COG0280	phosphate acetyltransferase
WU27_RS05325	COG0281	malic enzyme
WU27_RS05335	COG1522	sequence-specific DNA binding
WU27_RS05345	COG0567	Dehydrogenase, E1 component
WU27_RS05350	COG0508	dehydrogenase complex catalyzes the overall conversion of
WU27_RS05355	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WU27_RS05360	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
WU27_RS05365	COG1028	Short-chain dehydrogenase reductase Sdr
WU27_RS05370	COG0583	DNA-binding transcription factor activity
WU27_RS05380	COG3181	Tripartite tricarboxylate transporter family receptor
WU27_RS05405	COG0180	Tryptophanyl-tRNA synthetase
WU27_RS05410	COG2183	response to ionizing radiation
WU27_RS05415	COG1199	ATP-dependent helicase activity
WU27_RS05425	COG0564	pseudouridine synthase activity
WU27_RS05435	COG3243	poly(R)-hydroxyalkanoic acid synthase
WU27_RS05440	COG1028	Short-chain dehydrogenase reductase Sdr
WU27_RS05445	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
WU27_RS05460	COG0672	)-iron permease
WU27_RS05500	COG0583	DNA-binding transcription factor activity
WU27_RS05510	COG2814	Major facilitator Superfamily
WU27_RS05525	COG1619	proteins homologs of microcin C7 resistance protein MccF
WU27_RS05540	COG2084	Dehydrogenase
WU27_RS05545	COG3181	Tripartite tricarboxylate transporter family receptor
WU27_RS05570	COG2988	succinylglutamate desuccinylase activity
WU27_RS05600	COG0765	amino acid transport
WU27_RS05605	COG0765	amino acid transport
WU27_RS05610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WU27_RS05645	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WU27_RS05650	COG1595	DNA-templated transcription, initiation
WU27_RS05660	COG3530	Putative quorum-sensing-regulated virulence factor
WU27_RS05665	COG0494	nUDIX hydrolase
WU27_RS05680	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
WU27_RS05685	COG0542	response to heat
WU27_RS05700	COG3468	outer membrane autotransporter barrel domain protein
WU27_RS05705	COG3468	outer membrane autotransporter barrel domain protein
WU27_RS05715	COG5441	Belongs to the UPF0261 family
WU27_RS05720	COG5564	TIM-barrel signal transduction protein
WU27_RS05735	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
WU27_RS05750	COG1477	protein flavinylation
WU27_RS05770	COG1131	(ABC) transporter
WU27_RS05775	COG0842	Transport permease protein
WU27_RS05785	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
WU27_RS05790	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
WU27_RS05790	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
WU27_RS05795	COG1562	ergosterol biosynthetic process
WU27_RS05800	COG1562	ergosterol biosynthetic process
WU27_RS05805	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
WU27_RS05810	COG1028	Short-chain dehydrogenase reductase Sdr
WU27_RS05830	COG2304	oxidoreductase activity
WU27_RS05850	COG0534	Mate efflux family protein
WU27_RS05860	COG0254	rRNA binding
WU27_RS05865	COG3483	tryptophan 2,3-dioxygenase activity
WU27_RS05870	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
WU27_RS05875	COG2003	Belongs to the UPF0758 family
WU27_RS05880	COG1047	Peptidyl-prolyl cis-trans
WU27_RS05885	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
WU27_RS05890	COG0625	glutathione transferase activity
WU27_RS05910	COG0523	cobalamin synthesis protein
WU27_RS05920	COG0583	DNA-binding transcription factor activity
WU27_RS05930	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
WU27_RS05935	COG1187	pseudouridine synthase activity
WU27_RS05940	COG0779	Required for maturation of 30S ribosomal subunits
WU27_RS05945	COG2251	uridine kinase activity
WU27_RS05945	COG0195	Participates in both transcription termination and antitermination
WU27_RS05950	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
WU27_RS05955	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
WU27_RS05960	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
WU27_RS05980	COG1611	Belongs to the LOG family
WU27_RS05995	COG0412	Dienelactone hydrolase
WU27_RS06000	COG1283	sodium-dependent phosphate transmembrane transporter activity
WU27_RS06005	COG1760	l-serine dehydratase
WU27_RS06010	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
WU27_RS06015	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
WU27_RS06025	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
WU27_RS06050	COG2311	Membrane
WU27_RS06060	COG0697	spore germination
WU27_RS06075	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
WU27_RS06090	COG0559	Belongs to the binding-protein-dependent transport system permease family
WU27_RS06105	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
WU27_RS06115	COG1653	transport
WU27_RS06120	COG1175	transmembrane transport
WU27_RS06125	COG0395	ABC-type sugar transport system, permease component
WU27_RS06130	COG3842	ATPase activity
WU27_RS06155	COG2363	Small membrane protein
WU27_RS06170	COG1464	Belongs to the NlpA lipoprotein family
WU27_RS06180	COG0688	phosphatidylethanolamine metabolic process
WU27_RS06205	COG0625	glutathione transferase activity
WU27_RS06210	COG0386	Belongs to the glutathione peroxidase family
WU27_RS06230	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU27_RS06260	COG2259	Doxx family
WU27_RS06275	COG0667	Aldo Keto reductase
WU27_RS06305	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
WU27_RS06325	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
WU27_RS06335	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
WU27_RS06375	COG0392	lysyltransferase activity
WU27_RS06390	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WU27_RS06395	COG3568	Endonuclease Exonuclease Phosphatase
WU27_RS06405	COG1695	Transcriptional regulator
WU27_RS06425	COG0583	DNA-binding transcription factor activity
WU27_RS06440	COG1802	Transcriptional regulator
WU27_RS06450	COG3181	Tripartite tricarboxylate transporter family receptor
WU27_RS06460	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU27_RS06475	COG0066	3-isopropylmalate dehydratase activity
WU27_RS06485	COG3181	Tripartite tricarboxylate transporter family receptor
WU27_RS06490	COG4948	Mandelate Racemase Muconate Lactonizing
WU27_RS06505	COG1126	abc transporter atp-binding protein
WU27_RS06510	COG0765	amino acid transport
WU27_RS06515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WU27_RS06535	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
WU27_RS06560	COG1815	bacterial-type flagellum-dependent cell motility
WU27_RS06565	COG1558	bacterial-type flagellum-dependent cell motility
WU27_RS06575	COG1749	Flagellar hook protein flgE
WU27_RS06590	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
WU27_RS06595	COG1706	bacterial-type flagellum-dependent cell motility
WU27_RS06605	COG1256	bacterial-type flagellum assembly
WU27_RS06615	COG0840	transmembrane signaling receptor activity
WU27_RS06620	COG0840	transmembrane signaling receptor activity
WU27_RS06625	COG0840	transmembrane signaling receptor activity
WU27_RS06645	COG1338	Plays a role in the flagellum-specific transport system
WU27_RS06665	COG1580	Controls the rotational direction of flagella during chemotaxis
WU27_RS06690	COG1157	protein secretion by the type III secretion system
WU27_RS06700	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
WU27_RS06710	COG1677	Flagellar hook-basal body complex protein FliE
WU27_RS06720	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
WU27_RS06755	COG0285	dihydrofolate synthase activity
WU27_RS06785	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
WU27_RS06790	COG0024	Methionine aminopeptidase
WU27_RS06795	COG0052	Belongs to the universal ribosomal protein uS2 family
WU27_RS06800	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
WU27_RS06805	COG0528	UMP kinase activity
WU27_RS06810	COG0233	cytoplasmic translational termination
WU27_RS06815	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
WU27_RS06825	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
WU27_RS06830	COG0750	zinc metalloprotease
WU27_RS06835	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
WU27_RS06840	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
WU27_RS06845	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
WU27_RS06850	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
WU27_RS06860	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
WU27_RS06865	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
WU27_RS06870	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
WU27_RS06875	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
WU27_RS06885	COG0519	Catalyzes the synthesis of GMP from XMP
WU27_RS06885	COG0518	GMP synthase (glutamine-hydrolyzing) activity
WU27_RS06900	COG0330	HflC and HflK could
WU27_RS06905	COG3706	GGDEF domain
WU27_RS06910	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
WU27_RS06920	COG2867	negative regulation of translational initiation
WU27_RS06930	COG1960	acyl-CoA dehydrogenase activity
WU27_RS06935	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
WU27_RS06965	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
WU27_RS06970	COG0505	Belongs to the CarA family
WU27_RS06975	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
WU27_RS06985	COG0406	alpha-ribazole phosphatase activity
WU27_RS06995	COG3842	ATPase activity
WU27_RS07015	COG5001	Diguanylate cyclase
WU27_RS07020	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
WU27_RS07030	COG1763	Mo-molybdopterin cofactor biosynthetic process
WU27_RS07035	COG0303	'Molybdopterin
WU27_RS07040	COG0746	molybdenum cofactor guanylyltransferase activity
WU27_RS07045	COG0489	protein tyrosine kinase activity
WU27_RS07075	COG0243	molybdopterin cofactor binding
WU27_RS07075	COG3383	formate dehydrogenase (NAD+) activity
WU27_RS07080	COG0437	4 iron, 4 sulfur cluster binding
WU27_RS07110	COG1122	ATPase activity
WU27_RS07120	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
WU27_RS07125	COG0066	3-isopropylmalate dehydratase activity
WU27_RS07130	COG0473	3-isopropylmalate dehydrogenase activity
WU27_RS07135	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
WU27_RS07145	COG0101	tRNA pseudouridine synthase activity
WU27_RS07150	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
WU27_RS07165	COG0135	phosphoribosylanthranilate isomerase activity
WU27_RS07180	COG3022	response to hydroperoxide
WU27_RS07190	COG1289	transmembrane transporter activity
WU27_RS07195	COG3023	N-Acetylmuramoyl-L-alanine amidase
WU27_RS07205	COG0424	maF-like protein
WU27_RS07210	COG1399	metal-binding, possibly nucleic acid-binding protein
WU27_RS07215	COG0333	Belongs to the bacterial ribosomal protein bL32 family
WU27_RS07220	COG0416	fatty acid biosynthetic process
WU27_RS07225	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
WU27_RS07240	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
WU27_RS07245	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
WU27_RS07270	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WU27_RS07275	COG0481	GTPase activity
WU27_RS07280	COG0681	Belongs to the peptidase S26 family
WU27_RS07285	COG0571	ribonuclease III activity
WU27_RS07290	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
WU27_RS07295	COG1381	Involved in DNA repair and RecF pathway recombination
WU27_RS07305	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
WU27_RS07315	COG3181	Tripartite tricarboxylate transporter family receptor
WU27_RS07320	COG0670	Belongs to the BI1 family
WU27_RS07335	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
WU27_RS07345	COG0583	DNA-binding transcription factor activity
WU27_RS07360	COG0583	DNA-binding transcription factor activity
WU27_RS07375	COG0791	NLP P60 protein
WU27_RS07380	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
WU27_RS07385	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
WU27_RS07390	COG3193	protein, possibly involved in utilization of glycolate and propanediol
WU27_RS07400	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
WU27_RS07405	COG0697	spore germination
WU27_RS07410	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
WU27_RS07425	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
WU27_RS07455	COG1446	asparaginase
WU27_RS07460	COG4172	Belongs to the ABC transporter superfamily
WU27_RS07465	COG0747	negative chemotaxis
WU27_RS07475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WU27_RS07500	COG0504	CTP synthase activity
WU27_RS07505	COG2877	3-deoxy-8-phosphooctulonate synthase activity
WU27_RS07515	COG0148	phosphopyruvate hydratase activity
WU27_RS07520	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
WU27_RS07550	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
WU27_RS07560	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
WU27_RS07585	COG1981	membrane
WU27_RS07615	COG0039	L-malate dehydrogenase activity
WU27_RS07620	COG2188	Transcriptional regulator
WU27_RS07625	COG2009	succinate dehydrogenase
WU27_RS07630	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
WU27_RS07635	COG1053	succinate dehydrogenase
WU27_RS07640	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
WU27_RS07645	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
WU27_RS07650	COG0372	Belongs to the citrate synthase family
WU27_RS07670	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
WU27_RS07670	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
WU27_RS07680	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
WU27_RS07685	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
WU27_RS07700	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
WU27_RS07705	COG3842	ATPase activity
WU27_RS07710	COG1176	ABC-type spermidine putrescine transport system, permease component I
WU27_RS07715	COG1177	transmembrane transport
WU27_RS07740	COG1960	acyl-CoA dehydrogenase activity
WU27_RS07745	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
WU27_RS07750	COG0704	Plays a role in the regulation of phosphate uptake
WU27_RS07760	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
WU27_RS07765	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
WU27_RS07765	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
WU27_RS07770	COG1643	Atp-dependent helicase
WU27_RS07785	COG0438	transferase activity, transferring glycosyl groups
WU27_RS07790	COG0726	polysaccharide deacetylase
WU27_RS07795	COG0463	Glycosyl transferase, family 2
WU27_RS07800	COG0438	transferase activity, transferring glycosyl groups
WU27_RS07805	COG2194	sulfuric ester hydrolase activity
WU27_RS07830	COG0859	PFAM glycosyl transferase family 9
WU27_RS07835	COG1132	(ABC) transporter
WU27_RS07850	COG0077	Prephenate dehydratase
WU27_RS07855	COG1530	ribonuclease E activity
WU27_RS07905	COG1250	3-hydroxyacyl-CoA dehydrogenase
WU27_RS07910	COG0154	amidase activity
WU27_RS07920	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
WU27_RS07935	COG0495	leucyl-tRNA aminoacylation
WU27_RS07940	COG2814	Major facilitator Superfamily
WU27_RS07970	COG0267	Belongs to the bacterial ribosomal protein bL33 family
WU27_RS07975	COG0227	Belongs to the bacterial ribosomal protein bL28 family
WU27_RS07980	COG2814	Major facilitator Superfamily
WU27_RS07985	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
WU27_RS08000	COG4176	ABC-type proline glycine betaine transport system permease component
WU27_RS08010	COG1942	4-Oxalocrotonate Tautomerase
WU27_RS08015	COG0183	Belongs to the thiolase family
WU27_RS08025	COG1802	Transcriptional regulator
WU27_RS08035	COG1024	Enoyl-CoA hydratase
WU27_RS08040	COG0318	PFAM AMP-dependent synthetase and ligase
WU27_RS08045	COG0318	PFAM AMP-dependent synthetase and ligase
WU27_RS08055	COG2032	superoxide dismutase activity
WU27_RS08070	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
WU27_RS08095	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WU27_RS08100	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WU27_RS08110	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
WU27_RS08115	COG0736	holo-[acyl-carrier-protein] synthase activity
WU27_RS08120	COG1472	Belongs to the glycosyl hydrolase 3 family
WU27_RS08125	COG0322	excinuclease ABC activity
WU27_RS08130	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
WU27_RS08145	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
WU27_RS08145	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
WU27_RS08150	COG2224	Isocitrate lyase
WU27_RS08170	COG0559	Belongs to the binding-protein-dependent transport system permease family
WU27_RS08180	COG4638	Rieske (2fe-2S)
WU27_RS08190	COG1024	Enoyl-CoA hydratase
WU27_RS08200	COG0633	Ferredoxin
WU27_RS08205	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU27_RS08220	COG0183	Belongs to the thiolase family
WU27_RS08265	COG2346	COG2346, Truncated hemoglobins
WU27_RS08395	COG2207	Transcriptional regulator
WU27_RS08440	COG1132	(ABC) transporter
WU27_RS08465	COG0659	secondary active sulfate transmembrane transporter activity
WU27_RS08495	COG2169	Transcriptional regulator
WU27_RS08500	COG5507	3-demethylubiquinone-9 3-methyltransferase
WU27_RS08505	COG0384	phenazine biosynthesis protein PhzF
WU27_RS08510	COG0583	DNA-binding transcription factor activity
WU27_RS08515	COG2733	membrane
WU27_RS08530	COG1012	belongs to the aldehyde dehydrogenase family
WU27_RS08535	COG3284	Transcriptional regulator
WU27_RS08550	COG1380	Effector of murein hydrolase LrgA
WU27_RS08555	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
WU27_RS08555	COG4106	trans-aconitate 2-methyltransferase activity
WU27_RS08565	COG0156	8-amino-7-oxononanoate synthase activity
WU27_RS08635	COG1131	(ABC) transporter
WU27_RS08640	COG0842	Transport permease protein
WU27_RS08645	COG0628	permease
WU27_RS08680	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
WU27_RS08690	COG0828	Belongs to the bacterial ribosomal protein bS21 family
WU27_RS08695	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
WU27_RS08700	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
WU27_RS08705	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
WU27_RS08710	COG0330	HflC and HflK could
WU27_RS08715	COG0330	HflC and HflK could
WU27_RS08720	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
WU27_RS08725	COG1923	regulation of RNA biosynthetic process
WU27_RS08730	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
WU27_RS08735	COG1160	GTP binding
WU27_RS08740	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
WU27_RS08745	COG2976	Protein conserved in bacteria
WU27_RS08750	COG0124	histidyl-tRNA synthetase
WU27_RS08755	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
WU27_RS08765	COG0820	rRNA (adenine-C2-)-methyltransferase activity
WU27_RS08770	COG0105	UTP biosynthetic process
WU27_RS08775	COG0525	valine-tRNA ligase activity
WU27_RS08790	COG0642	Histidine kinase
WU27_RS08810	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
WU27_RS08815	COG0336	Belongs to the RNA methyltransferase TrmD family
WU27_RS08820	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
WU27_RS08825	COG0228	four-way junction DNA binding
WU27_RS08835	COG0425	Belongs to the sulfur carrier protein TusA family
WU27_RS08840	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
WU27_RS08885	COG0154	amidase activity
WU27_RS08890	COG4172	Belongs to the ABC transporter superfamily
WU27_RS08895	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WU27_RS08900	COG0601	transmembrane transport
WU27_RS08905	COG0747	negative chemotaxis
WU27_RS08935	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WU27_RS08945	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
WU27_RS08960	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
WU27_RS08965	COG3395	kinase activity
WU27_RS08980	COG1024	Enoyl-CoA hydratase
WU27_RS09000	COG0633	Ferredoxin
WU27_RS09005	COG0443	Heat shock 70 kDa protein
WU27_RS09010	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
WU27_RS09015	COG0316	Belongs to the HesB IscA family
WU27_RS09020	COG0822	iron-sulfur transferase activity
WU27_RS09025	COG1104	cysteine desulfurase activity
WU27_RS09035	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
WU27_RS09040	COG0556	nucleotide-excision repair
WU27_RS09050	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
WU27_RS09055	COG3468	outer membrane autotransporter barrel domain protein
WU27_RS09085	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
WU27_RS09100	COG1960	acyl-CoA dehydrogenase activity
WU27_RS09105	COG1028	Short-chain dehydrogenase reductase Sdr
WU27_RS09110	COG0183	Belongs to the thiolase family
WU27_RS09120	COG1024	Enoyl-CoA hydratase
WU27_RS09135	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU27_RS09140	COG0583	DNA-binding transcription factor activity
WU27_RS09145	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
WU27_RS09150	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
WU27_RS09155	COG0740	serine-type endopeptidase activity
WU27_RS09160	COG0544	peptidyl-prolyl cis-trans isomerase activity
WU27_RS09180	COG1278	Cold shock
WU27_RS09215	COG2171	N-acyltransferase activity
WU27_RS09220	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
WU27_RS09225	COG2890	protein-(glutamine-N5) methyltransferase activity
WU27_RS09230	COG0488	(ABC) transporter
WU27_RS09235	COG4771	TonB-dependent receptor
WU27_RS09240	COG0210	DNA helicase
WU27_RS09260	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
WU27_RS09265	COG0196	riboflavin kinase activity
WU27_RS09270	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
WU27_RS09275	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
WU27_RS09280	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
WU27_RS09290	COG1522	sequence-specific DNA binding
WU27_RS09310	COG2951	lytic endotransglycosylase activity
WU27_RS09315	COG2833	Protein of unknown function (DUF455)
WU27_RS09335	COG0189	ligase activity
WU27_RS09335	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
WU27_RS09340	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
WU27_RS09340	COG1181	Belongs to the D-alanine--D-alanine ligase family
WU27_RS09345	COG3237	CsbD-like
WU27_RS09355	COG2823	Periplasmic or secreted lipoprotein
WU27_RS09370	COG4181	ATPase activity
WU27_RS09380	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
WU27_RS09385	COG0584	glycerophosphoryl diester phosphodiesterase
WU27_RS09390	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
WU27_RS09400	COG0678	peroxiredoxin activity
WU27_RS09400	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
WU27_RS09410	COG0789	Transcriptional regulator
WU27_RS09415	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
WU27_RS09445	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
WU27_RS09450	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
WU27_RS09460	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
WU27_RS09465	COG2252	PERMEase
WU27_RS09475	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
WU27_RS09505	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
WU27_RS09510	COG2358	TRAP transporter, solute receptor (TAXI family
WU27_RS09540	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WU27_RS09545	COG1366	Belongs to the anti-sigma-factor antagonist family
WU27_RS09550	COG2172	sigma factor antagonist activity
WU27_RS09555	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
WU27_RS09565	COG2770	Histidine kinase
WU27_RS09565	COG2208	phosphoserine phosphatase activity
WU27_RS09590	COG1595	DNA-templated transcription, initiation
WU27_RS09605	COG4792	protein secretion
WU27_RS09610	COG4791	protein targeting
WU27_RS09615	COG4794	Type iii secretion
WU27_RS09620	COG4790	Type iii secretion
WU27_RS09655	COG4669	(LipO)protein
WU27_RS09720	COG4789	Type iii secretion
WU27_RS09750	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
WU27_RS09755	COG0840	transmembrane signaling receptor activity
WU27_RS09760	COG2233	PERMEase
WU27_RS09780	COG0492	ferredoxin-NADP+ reductase activity
WU27_RS09785	COG1840	ABC-type Fe3 transport system, periplasmic component
WU27_RS09790	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
WU27_RS09795	COG1178	ABC-type Fe3 transport system permease component
WU27_RS09800	COG3842	ATPase activity
WU27_RS09805	COG0583	DNA-binding transcription factor activity
WU27_RS09825	COG0501	Belongs to the peptidase M48B family
WU27_RS09835	COG0697	spore germination
WU27_RS09845	COG1846	Transcriptional regulator
WU27_RS09855	COG1566	PFAM secretion protein HlyD family protein
WU27_RS09860	COG2814	Major facilitator Superfamily
WU27_RS09865	COG0473	3-isopropylmalate dehydrogenase activity
WU27_RS09875	COG0747	negative chemotaxis
WU27_RS09885	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WU27_RS09900	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
WU27_RS09925	COG1012	belongs to the aldehyde dehydrogenase family
WU27_RS09935	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
WU27_RS09940	COG1115	amino acid carrier protein
WU27_RS09945	COG0433	COG0433 Predicted ATPase
WU27_RS09950	COG0217	transcriptional regulatory protein
WU27_RS09955	COG0151	Belongs to the GarS family
WU27_RS09960	COG0408	coproporphyrinogen oxidase activity
WU27_RS09965	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
WU27_RS09970	COG0799	negative regulation of ribosome biogenesis
WU27_RS09975	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
WU27_RS09980	COG0424	maF-like protein
WU27_RS09985	COG3468	outer membrane autotransporter barrel domain protein
WU27_RS10030	COG0427	acetyl-CoA hydrolase
WU27_RS10035	COG0583	DNA-binding transcription factor activity
WU27_RS10055	COG0730	response to heat
WU27_RS10060	COG0697	spore germination
WU27_RS10095	COG2885	chlorophyll binding
WU27_RS10130	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
WU27_RS10135	COG3384	dioxygenase
WU27_RS10150	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
WU27_RS10155	COG3474	cytochrome
WU27_RS10165	COG1595	DNA-templated transcription, initiation
WU27_RS10180	COG2204	response regulator
WU27_RS10220	COG4964	Belongs to the GSP D family
WU27_RS10270	COG1846	Transcriptional regulator
WU27_RS10275	COG4172	Belongs to the ABC transporter superfamily
WU27_RS10280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WU27_RS10285	COG0601	transmembrane transport
WU27_RS10290	COG0747	negative chemotaxis
WU27_RS10300	COG0598	Magnesium transport protein CorA
WU27_RS10305	COG0210	DNA helicase
WU27_RS10320	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
WU27_RS10325	COG1012	belongs to the aldehyde dehydrogenase family
WU27_RS10330	COG0483	inositol monophosphate 1-phosphatase activity
WU27_RS10335	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
WU27_RS10345	COG1045	serine acetyltransferase
WU27_RS10350	COG0166	Belongs to the GPI family
WU27_RS10365	COG2197	response regulator
WU27_RS10370	COG1846	Transcriptional regulator
WU27_RS10390	COG1649	PFAM Uncharacterised BCR, COG1649
WU27_RS10390	COG0726	polysaccharide deacetylase
WU27_RS10395	COG1215	transferase activity, transferring glycosyl groups
WU27_RS10405	COG1902	pentaerythritol trinitrate reductase activity
WU27_RS10430	COG0251	oxidation-reduction process
WU27_RS10440	COG1832	CoA-binding protein
WU27_RS10445	COG1414	Transcriptional regulator
WU27_RS10450	COG1902	pentaerythritol trinitrate reductase activity
WU27_RS10450	COG0446	pyridine nucleotide-disulphide oxidoreductase
WU27_RS10460	COG3842	ATPase activity
WU27_RS10490	COG0583	DNA-binding transcription factor activity
WU27_RS10500	COG1028	Short-chain dehydrogenase reductase Sdr
WU27_RS10505	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
WU27_RS10510	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
WU27_RS10525	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
WU27_RS10525	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
WU27_RS10530	COG1250	3-hydroxyacyl-CoA dehydrogenase
WU27_RS10555	COG0527	aspartate kinase activity
WU27_RS10560	COG0037	tRNA processing
WU27_RS10570	COG0825	malonyl-CoA metabolic process
WU27_RS10580	COG0215	cysteine-tRNA ligase activity
WU27_RS10595	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
WU27_RS10600	COG1968	undecaprenyl-diphosphatase activity
WU27_RS10605	COG1253	flavin adenine dinucleotide binding
WU27_RS10610	COG0483	inositol monophosphate 1-phosphatase activity
WU27_RS10630	COG0668	transmembrane transport
WU27_RS10655	COG0583	DNA-binding transcription factor activity
WU27_RS10680	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
WU27_RS10695	COG2831	hemolysin activation secretion protein
WU27_RS10700	COG3539	Fimbrial protein
WU27_RS10705	COG3188	usher protein
WU27_RS10710	COG3121	Chaperone
WU27_RS10720	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
WU27_RS10720	COG3210	domain, Protein
WU27_RS10720	COG3064	Membrane
WU27_RS10725	COG2197	response regulator
WU27_RS10730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WU27_RS10730	COG2205	protein histidine kinase activity
WU27_RS10740	COG4336	lyase activity
WU27_RS10765	COG2010	Cytochrome c
WU27_RS10770	COG3189	MarR family transcriptional regulator
WU27_RS10785	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
WU27_RS10795	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
WU27_RS10795	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
WU27_RS10805	COG0028	Belongs to the TPP enzyme family
WU27_RS10815	COG1012	belongs to the aldehyde dehydrogenase family
WU27_RS10820	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
WU27_RS10825	COG0010	Belongs to the arginase family
WU27_RS10830	COG1126	abc transporter atp-binding protein
WU27_RS10840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WU27_RS10855	COG0084	hydrolase, TatD family'
WU27_RS10860	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
WU27_RS10865	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
WU27_RS10870	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
WU27_RS10885	COG0587	DNA-directed DNA polymerase activity
WU27_RS10895	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WU27_RS10900	COG1959	2 iron, 2 sulfur cluster binding
WU27_RS10905	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WU27_RS10905	COG1017	nitric oxide dioxygenase activity
WU27_RS10940	COG0488	(ABC) transporter
WU27_RS10945	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
WU27_RS10960	COG1024	Enoyl-CoA hydratase
WU27_RS10965	COG1619	proteins homologs of microcin C7 resistance protein MccF
WU27_RS10970	COG0590	tRNA wobble adenosine to inosine editing
WU27_RS10995	COG2212	antiporter activity
WU27_RS11000	COG1863	multisubunit Na H antiporter MnhE subunit
WU27_RS11005	COG0651	ATP synthesis coupled electron transport
WU27_RS11010	COG1006	Multisubunit Na H antiporter MnhC subunit
WU27_RS11015	COG2111	Na H antiporter
WU27_RS11015	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
WU27_RS11020	COG3181	Tripartite tricarboxylate transporter family receptor
WU27_RS11035	COG0583	DNA-binding transcription factor activity
WU27_RS11040	COG1028	Short-chain dehydrogenase reductase Sdr
WU27_RS11070	COG0431	NADPH-dependent FMN reductase
WU27_RS11115	COG1028	Short-chain dehydrogenase reductase Sdr
WU27_RS11120	COG0179	Fumarylacetoacetate (FAA) hydrolase
WU27_RS11150	COG0625	glutathione transferase activity
WU27_RS11155	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
WU27_RS11160	COG2944	sequence-specific DNA binding
WU27_RS11170	COG2197	response regulator
WU27_RS11195	COG3119	arylsulfatase activity
WU27_RS11230	COG0714	Associated with various cellular activities
WU27_RS11250	COG1028	Short-chain dehydrogenase reductase Sdr
WU27_RS11255	COG0861	Integral membrane protein TerC family
WU27_RS11300	COG0300	oxidoreductase activity
WU27_RS11325	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
WU27_RS11340	COG0438	transferase activity, transferring glycosyl groups
WU27_RS11360	COG0463	Glycosyl transferase, family 2
WU27_RS11375	COG0783	Belongs to the Dps family
WU27_RS11390	COG0583	DNA-binding transcription factor activity
WU27_RS11395	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
WU27_RS11410	COG0656	L-ascorbic acid biosynthetic process
WU27_RS11420	COG0583	DNA-binding transcription factor activity
WU27_RS11430	COG1840	ABC-type Fe3 transport system, periplasmic component
WU27_RS11435	COG1178	ABC-type Fe3 transport system permease component
WU27_RS11440	COG3842	ATPase activity
WU27_RS11450	COG1741	Belongs to the pirin family
WU27_RS11455	COG1741	Belongs to the pirin family
WU27_RS11460	COG0583	DNA-binding transcription factor activity
WU27_RS11465	COG2204	response regulator
WU27_RS11475	COG0174	glutamine synthetase
WU27_RS11480	COG0635	Involved in the biosynthesis of porphyrin-containing compound
WU27_RS11490	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
WU27_RS11495	COG2200	EAL domain
WU27_RS11495	COG2199	diguanylate cyclase activity
WU27_RS11500	COG0840	transmembrane signaling receptor activity
WU27_RS11515	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
WU27_RS11520	COG1561	YicC-like family, N-terminal region
WU27_RS11540	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
WU27_RS11545	COG0791	NLP P60 protein
WU27_RS11550	COG1028	Short-chain dehydrogenase reductase Sdr
WU27_RS11555	COG2863	cytochrome
WU27_RS11560	COG3258	Cytochrome c
WU27_RS11565	COG0194	GDP metabolic process
WU27_RS11570	COG1758	RNA polymerase activity
WU27_RS11575	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
WU27_RS11580	COG1126	abc transporter atp-binding protein
WU27_RS11585	COG0765	amino acid transport
WU27_RS11590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WU27_RS11610	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WU27_RS11615	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
WU27_RS11620	COG3539	Fimbrial protein
WU27_RS11625	COG2850	peptidyl-arginine hydroxylation
WU27_RS11630	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
WU27_RS11635	COG3360	Dodecin
WU27_RS11680	COG0009	L-threonylcarbamoyladenylate synthase
WU27_RS11685	COG2321	neutral zinc metallopeptidase
WU27_RS11705	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
WU27_RS11710	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
WU27_RS11715	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
WU27_RS11730	COG1074	ATP-dependent DNA helicase activity
WU27_RS11740	COG2814	Major facilitator Superfamily
WU27_RS11750	COG1686	Belongs to the peptidase S11 family
WU27_RS11765	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
WU27_RS11770	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
WU27_RS11775	COG4974	Belongs to the 'phage' integrase family
WU27_RS11780	COG0583	DNA-binding transcription factor activity
WU27_RS11785	COG0028	Belongs to the TPP enzyme family
WU27_RS11800	COG0028	Belongs to the TPP enzyme family
WU27_RS11805	COG1126	abc transporter atp-binding protein
WU27_RS11810	COG0765	amino acid transport
WU27_RS11825	COG1414	Transcriptional regulator
WU27_RS11830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WU27_RS11835	COG0009	L-threonylcarbamoyladenylate synthase
WU27_RS11840	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
WU27_RS11845	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
WU27_RS11850	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
WU27_RS11860	COG2944	sequence-specific DNA binding
WU27_RS11870	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
WU27_RS11925	COG1126	abc transporter atp-binding protein
WU27_RS11930	COG0765	amino acid transport
WU27_RS11935	COG0765	amino acid transport
WU27_RS11940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WU27_RS11950	COG2423	ornithine cyclodeaminase activity
WU27_RS11955	COG1764	response to oxidative stress
WU27_RS11965	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
WU27_RS11970	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
WU27_RS11980	COG0189	ligase activity
WU27_RS11985	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
WU27_RS11990	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
WU27_RS11995	COG2197	response regulator
WU27_RS12005	COG0635	Involved in the biosynthesis of porphyrin-containing compound
WU27_RS12025	COG1289	transmembrane transporter activity
WU27_RS12035	COG3022	response to hydroperoxide
WU27_RS12045	COG1028	Short-chain dehydrogenase reductase Sdr
WU27_RS12060	COG3486	L-lysine 6-monooxygenase (NADPH) activity
WU27_RS12090	COG2814	Major facilitator Superfamily
WU27_RS12110	COG3706	GGDEF domain
WU27_RS12135	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
WU27_RS12140	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
WU27_RS12145	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
WU27_RS12150	COG1674	ftsk spoiiie
WU27_RS12155	COG0492	ferredoxin-NADP+ reductase activity
WU27_RS12160	COG1193	negative regulation of DNA recombination
WU27_RS12180	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
WU27_RS12195	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
WU27_RS12200	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
WU27_RS12205	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
WU27_RS12215	COG0745	RESPONSE REGULATOR receiver
WU27_RS12260	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
WU27_RS12280	COG0612	Peptidase, M16
WU27_RS12290	COG0443	Heat shock 70 kDa protein
WU27_RS12300	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
WU27_RS12310	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
WU27_RS12315	COG1420	regulation of RNA biosynthetic process
WU27_RS12320	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
WU27_RS12325	COG0497	DNA recombination
WU27_RS12330	COG0735	belongs to the Fur family
WU27_RS12335	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
WU27_RS12340	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
WU27_RS12345	COG0812	UDP-N-acetylmuramate dehydrogenase activity
WU27_RS12380	COG0446	pyridine nucleotide-disulphide oxidoreductase
WU27_RS12380	COG0404	The glycine cleavage system catalyzes the degradation of glycine
WU27_RS12385	COG4311	Sarcosine oxidase, delta subunit
WU27_RS12390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WU27_RS12400	COG0583	DNA-binding transcription factor activity
WU27_RS12410	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
WU27_RS12440	COG4964	Belongs to the GSP D family
WU27_RS12500	COG0181	hydroxymethylbilane synthase activity
WU27_RS12505	COG0861	Integral membrane protein TerC family
WU27_RS12510	COG0861	Integral membrane protein TerC family
WU27_RS12515	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
WU27_RS12520	COG0045	succinate-CoA ligase (ADP-forming) activity
WU27_RS12530	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
WU27_RS12540	COG2137	regulation of response to DNA damage stimulus
WU27_RS12545	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
WU27_RS12565	COG1024	Enoyl-CoA hydratase
WU27_RS12565	COG1250	3-hydroxyacyl-CoA dehydrogenase
WU27_RS12570	COG3842	ATPase activity
WU27_RS12585	COG1028	Short-chain dehydrogenase reductase Sdr
WU27_RS12605	COG0583	DNA-binding transcription factor activity
WU27_RS12610	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU27_RS12620	COG2974	May be involved in recombination
WU27_RS12625	COG0540	Belongs to the ATCase OTCase family
WU27_RS12700	COG0776	regulation of translation
WU27_RS12705	COG0072	phenylalanine-tRNA ligase activity
WU27_RS12705	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WU27_RS12710	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
WU27_RS12715	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
WU27_RS12720	COG0291	Belongs to the bacterial ribosomal protein bL35 family
WU27_RS12735	COG0756	dUTP diphosphatase activity
WU27_RS12745	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WU27_RS12760	COG0500	methyltransferase
WU27_RS12775	COG0586	Pfam SNARE associated Golgi protein
WU27_RS12805	COG1609	Transcriptional regulator
WU27_RS12810	COG4172	Belongs to the ABC transporter superfamily
WU27_RS12815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WU27_RS12820	COG0601	transmembrane transport
WU27_RS12825	COG0747	negative chemotaxis
WU27_RS12840	COG1280	lysine exporter protein (LysE YggA)
WU27_RS12855	COG2814	Major facilitator Superfamily
WU27_RS12885	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
WU27_RS12905	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
WU27_RS12945	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WU27_RS12950	COG1116	anion transmembrane transporter activity
WU27_RS12960	COG1228	amidohydrolase
WU27_RS12975	COG0477	Major facilitator Superfamily
WU27_RS12985	COG3550	peptidyl-serine autophosphorylation
WU27_RS13000	COG0518	GMP synthase (glutamine-hydrolyzing) activity
WU27_RS13000	COG0519	Catalyzes the synthesis of GMP from XMP
WU27_RS13045	COG0420	3'-5' exonuclease activity
WU27_RS13050	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WU27_RS13080	COG0395	ABC-type sugar transport system, permease component
WU27_RS13090	COG3842	ATPase activity
WU27_RS13120	COG3181	Tripartite tricarboxylate transporter family receptor
WU27_RS13155	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WU27_RS13180	COG0602	queuosine metabolic process
WU27_RS13185	COG0720	synthase
WU27_RS13190	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
WU27_RS13195	COG0235	Class ii aldolase
WU27_RS13220	COG3210	domain, Protein
WU27_RS13220	COG3064	Membrane
WU27_RS13220	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
WU27_RS13225	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
WU27_RS13225	COG0047	phosphoribosylformylglycinamidine synthase activity
WU27_RS13230	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
WU27_RS13235	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
WU27_RS13235	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
WU27_RS13240	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
WU27_RS13260	COG3539	Fimbrial protein
WU27_RS13270	COG2050	protein possibly involved in aromatic compounds catabolism
WU27_RS13275	COG1024	Enoyl-CoA hydratase
WU27_RS13280	COG1012	belongs to the aldehyde dehydrogenase family
WU27_RS13290	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WU27_RS13295	COG2151	metal-sulfur cluster biosynthetic enzyme
WU27_RS13300	COG3396	Phenylacetate-CoA oxygenase
WU27_RS13305	COG3460	Phenylacetate-CoA oxygenase
WU27_RS13310	COG3396	Phenylacetate-CoA oxygenase
WU27_RS13315	COG3327	negative regulation of DNA-templated transcription, initiation
WU27_RS13325	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
WU27_RS13330	COG0501	Belongs to the peptidase M48B family
WU27_RS13335	COG1162	GTPase activity
WU27_RS13340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WU27_RS13345	COG0601	transmembrane transport
WU27_RS13350	COG0747	negative chemotaxis
WU27_RS13395	COG0668	transmembrane transport
WU27_RS13400	COG0165	Argininosuccinate lyase
WU27_RS13420	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
WU27_RS13425	COG0303	'Molybdopterin
WU27_RS13430	COG0521	Mo-molybdopterin cofactor biosynthetic process
WU27_RS13445	COG0315	cyclic pyranopterin monophosphate synthase activity
WU27_RS13455	COG0412	Dienelactone hydrolase
WU27_RS13465	COG0678	peroxiredoxin activity
WU27_RS13475	COG0697	spore germination
WU27_RS13480	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
WU27_RS13505	COG0789	Transcriptional regulator
WU27_RS13525	COG1028	Short-chain dehydrogenase reductase Sdr
WU27_RS13535	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
WU27_RS13540	COG1845	cytochrome c oxidase, subunit III
WU27_RS13545	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
WU27_RS13555	COG0477	Major facilitator Superfamily
WU27_RS13585	COG3468	outer membrane autotransporter barrel domain protein
WU27_RS13595	COG1309	transcriptional regulator
WU27_RS13600	COG2271	Major facilitator Superfamily
WU27_RS13635	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
WU27_RS13635	COG0506	proline dehydrogenase activity
WU27_RS13635	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
WU27_RS13645	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
WU27_RS13645	COG3008	intermembrane lipid transfer
WU27_RS13650	COG2995	paraquat-inducible protein a
WU27_RS13655	COG0542	response to heat
WU27_RS13660	COG4953	penicillin-binding protein 1C
WU27_RS13670	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
WU27_RS13675	COG1278	Cold shock
WU27_RS13685	COG0183	Belongs to the thiolase family
WU27_RS13690	COG0038	chloride channel
WU27_RS13695	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
WU27_RS13700	COG1570	exodeoxyribonuclease VII activity
WU27_RS13710	COG0811	peptide transport
WU27_RS13715	COG0848	biopolymer transport protein
WU27_RS13720	COG1663	tetraacyldisaccharide 4'-kinase activity
WU27_RS13725	COG2835	tetraacyldisaccharide 4'-kinase activity
WU27_RS13730	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
WU27_RS13735	COG0563	adenylate kinase activity
WU27_RS13745	COG0728	peptidoglycan biosynthetic process
WU27_RS13755	COG0268	Binds directly to 16S ribosomal RNA
WU27_RS13785	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
WU27_RS13810	COG0436	Aminotransferase
WU27_RS13815	COG3737	Protein of unknown function (DUF498/DUF598)
WU27_RS13820	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
WU27_RS13825	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
WU27_RS13830	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
WU27_RS13840	COG0305	Participates in initiation and elongation during chromosome replication
WU27_RS13850	COG0359	binds to the 23S rRNA
WU27_RS13855	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
WU27_RS13860	COG2965	DNA replication, synthesis of RNA primer
WU27_RS13865	COG0360	Binds together with S18 to 16S ribosomal RNA
WU27_RS13870	COG1469	GTP cyclohydrolase I activity
WU27_RS13875	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
WU27_RS13880	COG0142	geranyltranstransferase activity
WU27_RS13885	COG1722	exodeoxyribonuclease VII activity
WU27_RS13895	COG3181	Tripartite tricarboxylate transporter family receptor
WU27_RS13915	COG2239	Acts as a magnesium transporter
WU27_RS13925	COG2855	membrane
WU27_RS13935	COG1473	amidohydrolase
WU27_RS13940	COG0318	PFAM AMP-dependent synthetase and ligase
WU27_RS13965	COG1501	Belongs to the glycosyl hydrolase 31 family
WU27_RS13970	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
WU27_RS13975	COG2011	ABC-type metal ion transport system permease component
WU27_RS13995	COG1454	alcohol dehydrogenase
WU27_RS14025	COG2186	Transcriptional regulator
WU27_RS14030	COG3181	Tripartite tricarboxylate transporter family receptor
WU27_RS14055	COG1175	transmembrane transport
WU27_RS14060	COG0395	ABC-type sugar transport system, permease component
WU27_RS14065	COG3842	ATPase activity
WU27_RS14070	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WU27_RS14080	COG1653	transport
WU27_RS14100	COG2818	Glycosylase
WU27_RS14105	COG2982	Protein involved in outer membrane biogenesis
WU27_RS14115	COG1309	transcriptional regulator
WU27_RS14120	COG1028	Short-chain dehydrogenase reductase Sdr
WU27_RS14180	COG0583	DNA-binding transcription factor activity
WU27_RS14185	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
WU27_RS14190	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WU27_RS14205	COG1028	Short-chain dehydrogenase reductase Sdr
WU27_RS14210	COG0477	Major facilitator Superfamily
WU27_RS14220	COG0583	DNA-binding transcription factor activity
WU27_RS14225	COG1448	Aminotransferase
WU27_RS14230	COG1418	mRNA catabolic process
WU27_RS14255	COG1063	alcohol dehydrogenase
WU27_RS14275	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WU27_RS14285	COG0318	PFAM AMP-dependent synthetase and ligase
WU27_RS14295	COG1522	sequence-specific DNA binding
WU27_RS14300	COG3181	Tripartite tricarboxylate transporter family receptor
WU27_RS14305	COG0307	riboflavin synthase, alpha
WU27_RS14310	COG0154	amidase activity
WU27_RS14330	COG2807	transmembrane transport
WU27_RS14335	COG0590	tRNA wobble adenosine to inosine editing
WU27_RS14345	COG0583	DNA-binding transcription factor activity
WU27_RS14360	COG1902	pentaerythritol trinitrate reductase activity
WU27_RS14380	COG0559	Belongs to the binding-protein-dependent transport system permease family
WU27_RS14385	COG0251	oxidation-reduction process
WU27_RS14390	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
WU27_RS14400	COG1414	Transcriptional regulator
WU27_RS14405	COG1028	Short-chain dehydrogenase reductase Sdr
WU27_RS14420	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WU27_RS14435	COG1024	Enoyl-CoA hydratase
WU27_RS14440	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU27_RS14445	COG0154	amidase activity
WU27_RS14485	COG3909	cytochrome
WU27_RS14490	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
WU27_RS14495	COG0625	glutathione transferase activity
WU27_RS14500	COG0730	response to heat
WU27_RS14505	COG0482	sulfurtransferase activity
WU27_RS14510	COG0583	DNA-binding transcription factor activity
WU27_RS14530	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
WU27_RS14555	COG2819	hydrolase of the alpha beta superfamily
WU27_RS14560	COG0247	lactate metabolic process
WU27_RS14565	COG0277	FAD linked oxidase domain protein
WU27_RS14570	COG0277	FAD linked oxidase domain protein
WU27_RS14575	COG0277	FAD linked oxidase domain protein
WU27_RS14580	COG3210	domain, Protein
WU27_RS14580	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
WU27_RS14580	COG3210	domain, Protein
WU27_RS14580	COG3064	Membrane
WU27_RS14580	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
WU27_RS14580	COG3064	Membrane
WU27_RS14585	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
WU27_RS14590	COG0312	modulator of DNA gyrase
WU27_RS14625	COG1666	GTP binding
WU27_RS14670	COG3220	belongs to the UPF0276 family
WU27_RS14690	COG0640	Transcriptional regulator
WU27_RS14695	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
WU27_RS14700	COG1845	cytochrome c oxidase, subunit III
WU27_RS14705	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
WU27_RS14715	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
WU27_RS14750	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU27_RS14755	COG0583	DNA-binding transcription factor activity
WU27_RS14785	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
WU27_RS14785	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
WU27_RS14800	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
WU27_RS14805	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
WU27_RS14815	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
WU27_RS14830	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
WU27_RS14835	COG0316	Belongs to the HesB IscA family
WU27_RS14845	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
WU27_RS14850	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
WU27_RS14855	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
WU27_RS14860	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
WU27_RS14865	COG0312	modulator of DNA gyrase
WU27_RS14870	COG3028	Belongs to the UPF0307 family
WU27_RS14885	COG1116	anion transmembrane transporter activity
WU27_RS14890	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WU27_RS14895	COG1335	isochorismatase
WU27_RS14900	COG0346	lactoylglutathione lyase activity
WU27_RS14905	COG0513	Belongs to the DEAD box helicase family
WU27_RS14910	COG3069	C4-dicarboxylate transmembrane transporter activity
WU27_RS14915	COG1802	Transcriptional regulator
WU27_RS14930	COG0045	succinate-CoA ligase (ADP-forming) activity
WU27_RS14930	COG1042	CoA-binding domain protein
WU27_RS14930	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WU27_RS14935	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
WU27_RS14950	COG1522	sequence-specific DNA binding
WU27_RS14985	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
WU27_RS14990	COG1696	Membrane protein involved in D-alanine export
WU27_RS15015	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WU27_RS15025	COG2264	protein methyltransferase activity
WU27_RS15030	COG0439	Biotin carboxylase
WU27_RS15035	COG0511	ligase activity, forming carbon-carbon bonds
WU27_RS15040	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
WU27_RS15045	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
WU27_RS15050	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
WU27_RS15055	COG3150	esterase
WU27_RS15060	COG0557	exoribonuclease II activity
WU27_RS15070	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
WU27_RS15090	COG1522	sequence-specific DNA binding
WU27_RS15095	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WU27_RS15100	COG1028	Short-chain dehydrogenase reductase Sdr
WU27_RS15120	COG0653	protein targeting
WU27_RS15125	COG0739	heme binding
WU27_RS15135	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
WU27_RS15140	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
WU27_RS15150	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
WU27_RS15155	COG1181	Belongs to the D-alanine--D-alanine ligase family
WU27_RS15160	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
WU27_RS15165	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
WU27_RS15175	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
WU27_RS15180	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
WU27_RS15185	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
WU27_RS15195	COG3116	cell division
WU27_RS15200	COG0275	rRNA processing
WU27_RS15205	COG2001	Belongs to the MraZ family
WU27_RS15215	COG0488	(ABC) transporter
WU27_RS15220	COG0418	dihydroorotase activity
WU27_RS15225	COG1473	amidohydrolase
WU27_RS15275	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
WU27_RS15280	COG4654	Cytochrome c, class I
WU27_RS15285	COG0129	dihydroxy-acid dehydratase activity
WU27_RS15290	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
WU27_RS15340	COG2084	Dehydrogenase
WU27_RS15345	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
WU27_RS15360	COG2096	Adenosyltransferase
WU27_RS15370	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
WU27_RS15375	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
WU27_RS15385	COG0523	cobalamin synthesis protein
WU27_RS15390	COG0735	belongs to the Fur family
WU27_RS15410	COG0803	Belongs to the bacterial solute-binding protein 9 family
WU27_RS15420	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
WU27_RS15430	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
WU27_RS15440	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
WU27_RS15445	COG1560	Kdo2-lipid A biosynthetic process
WU27_RS15455	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
WU27_RS15470	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
WU27_RS15475	COG1950	PFAM Membrane protein of
WU27_RS15490	COG0583	DNA-binding transcription factor activity
WU27_RS15500	COG0477	Major facilitator Superfamily
WU27_RS15515	COG0617	tRNA 3'-terminal CCA addition
WU27_RS15525	COG0513	Belongs to the DEAD box helicase family
WU27_RS15530	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
WU27_RS15545	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WU27_RS15550	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
WU27_RS15610	COG1280	lysine exporter protein (LysE YggA)
WU27_RS15625	COG0405	Gamma-glutamyltransferase
WU27_RS15635	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WU27_RS15665	COG1309	transcriptional regulator
WU27_RS15675	COG3181	Tripartite tricarboxylate transporter family receptor
WU27_RS15685	COG0745	RESPONSE REGULATOR receiver
WU27_RS15750	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
WU27_RS15775	COG0582	viral genome integration into host DNA
WU27_RS15780	COG0012	GTP binding
WU27_RS15790	COG0193	aminoacyl-tRNA hydrolase activity
WU27_RS15795	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
WU27_RS15800	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
WU27_RS15810	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
WU27_RS15815	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
WU27_RS15825	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
WU27_RS15850	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
WU27_RS15860	COG1368	sulfuric ester hydrolase activity
WU27_RS15865	COG0642	Histidine kinase
WU27_RS15870	COG0745	RESPONSE REGULATOR receiver
WU27_RS15875	COG0277	FAD linked oxidase domain protein
WU27_RS15890	COG0166	Belongs to the GPI family
WU27_RS15895	COG0438	transferase activity, transferring glycosyl groups
WU27_RS15900	COG0438	transferase activity, transferring glycosyl groups
WU27_RS15915	COG0438	transferase activity, transferring glycosyl groups
WU27_RS15930	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
WU27_RS15935	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
WU27_RS15940	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
WU27_RS15950	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
WU27_RS15960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WU27_RS15965	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
WU27_RS15975	COG0747	negative chemotaxis
WU27_RS15980	COG0601	transmembrane transport
WU27_RS15985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WU27_RS16005	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
WU27_RS16010	COG0830	nickel cation binding
WU27_RS16020	COG0804	urea catabolic process
WU27_RS16025	COG0832	Belongs to the urease beta subunit family
WU27_RS16035	COG0831	urea catabolic process
WU27_RS16040	COG0829	nickel cation binding
WU27_RS16050	COG0633	Ferredoxin
WU27_RS16065	COG2188	Transcriptional regulator
WU27_RS16090	COG2719	SpoVR family
WU27_RS16095	COG2718	Belongs to the UPF0229 family
WU27_RS16110	COG1028	Short-chain dehydrogenase reductase Sdr
WU27_RS16115	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU27_RS16130	COG1960	acyl-CoA dehydrogenase activity
WU27_RS16175	COG0183	Belongs to the thiolase family
WU27_RS16180	COG2030	dehydratase
WU27_RS16235	COG0328	RNA-DNA hybrid ribonuclease activity
WU27_RS16240	COG2226	methyltransferase
WU27_RS16245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WU27_RS16250	COG1388	LysM domain
WU27_RS16250	COG0741	lytic transglycosylase activity
WU27_RS16270	COG2979	Protein of unknown function (DUF533)
WU27_RS16305	COG1271	oxidase subunit
WU27_RS16310	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
WU27_RS16315	COG0850	regulation of cytokinetic process
WU27_RS16320	COG2894	cell division
WU27_RS16325	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
WU27_RS16345	COG0488	(ABC) transporter
WU27_RS16360	COG0601	transmembrane transport
WU27_RS16370	COG1215	transferase activity, transferring glycosyl groups
WU27_RS16385	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
WU27_RS16395	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
WU27_RS16415	COG0318	PFAM AMP-dependent synthetase and ligase
WU27_RS16420	COG2188	Transcriptional regulator
WU27_RS16425	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
WU27_RS16430	COG2814	Major facilitator Superfamily
WU27_RS16440	COG0259	pyridoxamine-phosphate oxidase activity
WU27_RS16445	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
WU27_RS16460	COG0583	DNA-binding transcription factor activity
WU27_RS16465	COG1960	acyl-CoA dehydrogenase activity
WU27_RS16485	COG0134	indole-3-glycerol-phosphate synthase activity
WU27_RS16490	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
WU27_RS16495	COG0512	Glutamine amidotransferase of anthranilate synthase
WU27_RS16505	COG0546	phosphoglycolate phosphatase activity
WU27_RS16510	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
WU27_RS16515	COG2967	ApaG domain
WU27_RS16520	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
WU27_RS16525	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WU27_RS16530	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
WU27_RS16535	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
WU27_RS16545	COG0037	tRNA processing
WU27_RS16555	COG3634	alkyl hydroperoxide reductase activity
WU27_RS16560	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WU27_RS16565	COG1024	Enoyl-CoA hydratase
WU27_RS16590	COG0356	it plays a direct role in the translocation of protons across the membrane
WU27_RS16600	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
WU27_RS16605	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
WU27_RS16610	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
WU27_RS16615	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
WU27_RS16620	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
WU27_RS16625	COG0355	proton-transporting ATP synthase activity, rotational mechanism
WU27_RS16635	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
WU27_RS16640	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
WU27_RS16645	COG0210	DNA helicase
WU27_RS16655	COG2195	Cleaves the N-terminal amino acid of tripeptides
WU27_RS16665	COG4172	Belongs to the ABC transporter superfamily
WU27_RS16670	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WU27_RS16675	COG0601	transmembrane transport
WU27_RS16695	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
WU27_RS16700	COG1024	Enoyl-CoA hydratase
WU27_RS16705	COG1024	Enoyl-CoA hydratase
WU27_RS16730	COG1250	3-hydroxyacyl-CoA dehydrogenase
WU27_RS16760	COG2132	Multicopper oxidase
WU27_RS16770	COG1024	Enoyl-CoA hydratase
WU27_RS16770	COG1250	3-hydroxyacyl-CoA dehydrogenase
WU27_RS16780	COG1414	Transcriptional regulator
WU27_RS16790	COG0154	amidase activity
WU27_RS16820	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WU27_RS16825	COG3568	Endonuclease Exonuclease Phosphatase
WU27_RS16830	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
WU27_RS16870	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
WU27_RS16880	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
WU27_RS16895	COG1137	ATPase activity
WU27_RS16900	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
WU27_RS16910	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
WU27_RS16915	COG2010	Cytochrome c
WU27_RS16915	COG1529	Aldehyde oxidase and xanthine dehydrogenase
WU27_RS16925	COG1660	Displays ATPase and GTPase activities
WU27_RS16930	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
WU27_RS16965	COG3181	Tripartite tricarboxylate transporter family receptor
WU27_RS16975	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
WU27_RS16980	COG2890	protein-(glutamine-N5) methyltransferase activity
WU27_RS16985	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
WU27_RS16990	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
WU27_RS17040	COG1960	acyl-CoA dehydrogenase activity
WU27_RS17050	COG0183	Belongs to the thiolase family
WU27_RS17055	COG1522	sequence-specific DNA binding
WU27_RS17060	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
WU27_RS17080	COG1024	Enoyl-CoA hydratase
WU27_RS17095	COG0604	alcohol dehydrogenase
WU27_RS17100	COG2072	flavoprotein involved in K transport
WU27_RS17115	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
WU27_RS17125	COG1960	acyl-CoA dehydrogenase activity
WU27_RS17130	COG1960	acyl-CoA dehydrogenase activity
WU27_RS17135	COG0277	FAD linked oxidase domain protein
WU27_RS17145	COG3181	Tripartite tricarboxylate transporter family receptor
WU27_RS17170	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WU27_RS17175	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
WU27_RS17190	COG2031	fatty acid transporter
WU27_RS17200	COG0786	glutamate:sodium symporter activity
WU27_RS17220	COG0463	Glycosyl transferase, family 2
WU27_RS17225	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
WU27_RS17255	COG0697	spore germination
WU27_RS17265	COG3181	Tripartite tricarboxylate transporter family receptor
WU27_RS17290	COG0028	Belongs to the TPP enzyme family
WU27_RS17295	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU27_RS17300	COG1024	Enoyl-CoA hydratase
WU27_RS17300	COG1250	3-hydroxyacyl-CoA dehydrogenase
WU27_RS17305	COG3181	Tripartite tricarboxylate transporter family receptor
WU27_RS17315	COG0492	ferredoxin-NADP+ reductase activity
WU27_RS17335	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU27_RS17345	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU27_RS17365	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
WU27_RS17380	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
WU27_RS17385	COG2823	Periplasmic or secreted lipoprotein
WU27_RS17400	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
WU27_RS17410	COG1309	transcriptional regulator
WU27_RS17415	COG0471	metal ion transport
WU27_RS17420	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
WU27_RS17425	COG0772	Belongs to the SEDS family
WU27_RS17430	COG0768	penicillin binding
WU27_RS17440	COG1792	Involved in formation and maintenance of cell shape
WU27_RS17445	COG1077	Cell shape determining protein MreB Mrl
WU27_RS17450	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
WU27_RS17455	COG0154	amidase activity
WU27_RS17460	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
WU27_RS17465	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
WU27_RS17470	COG0708	Exodeoxyribonuclease III
WU27_RS17475	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
WU27_RS17480	COG2860	membrane
WU27_RS17515	COG1012	belongs to the aldehyde dehydrogenase family
WU27_RS17525	COG3069	C4-dicarboxylate transmembrane transporter activity
WU27_RS17535	COG1802	Transcriptional regulator
WU27_RS17570	COG1595	DNA-templated transcription, initiation
WU27_RS17575	COG3712	iron ion homeostasis
WU27_RS17585	COG3720	iron ion transport
WU27_RS17590	COG4558	Periplasmic binding protein
WU27_RS17595	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WU27_RS17600	COG1120	ATPase activity
WU27_RS17605	COG1683	Conserved Protein
WU27_RS17635	COG3064	Membrane
WU27_RS17655	COG1234	tRNA 3'-trailer cleavage
WU27_RS17690	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
WU27_RS17700	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
WU27_RS17715	COG0540	Belongs to the ATCase OTCase family
WU27_RS17720	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
WU27_RS17725	COG1678	Uncharacterized ACR, COG1678
WU27_RS17740	COG0352	thiamine-phosphate diphosphorylase activity
WU27_RS17745	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
WU27_RS17770	COG1960	acyl-CoA dehydrogenase activity
WU27_RS17775	COG1024	Enoyl-CoA hydratase
WU27_RS17845	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
WU27_RS17855	COG0583	DNA-binding transcription factor activity
WU27_RS17860	COG2814	Major facilitator Superfamily
WU27_RS17865	COG0129	dihydroxy-acid dehydratase activity
WU27_RS17870	COG2207	Transcriptional regulator
WU27_RS17875	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
WU27_RS17885	COG0657	acetylesterase activity
WU27_RS17890	COG0747	negative chemotaxis
WU27_RS17895	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
WU27_RS17900	COG2808	Putative FMN-binding domain
WU27_RS17915	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
WU27_RS17920	COG1970	mechanosensitive ion channel activity
WU27_RS17925	COG0723	plastoquinol--plastocyanin reductase activity
WU27_RS17930	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
WU27_RS17935	COG2857	Cytochrome c1
WU27_RS17940	COG0625	glutathione transferase activity
WU27_RS17945	COG2969	positive regulation of protein catabolic process
WU27_RS17975	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WU27_RS17990	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
WU27_RS17995	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
WU27_RS18000	COG4988	ABC transporter
WU27_RS18010	COG1294	oxidase, subunit
WU27_RS18035	COG1960	acyl-CoA dehydrogenase activity
WU27_RS18045	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU27_RS18050	COG0405	Gamma-glutamyltransferase
WU27_RS18060	COG3181	Tripartite tricarboxylate transporter family receptor
WU27_RS18070	COG0114	fumarate hydratase activity
WU27_RS18075	COG0802	atpase or kinase
WU27_RS18080	COG0860	N-Acetylmuramoyl-L-alanine amidase
WU27_RS18085	COG0586	Pfam SNARE associated Golgi protein
WU27_RS18090	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
WU27_RS18095	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
WU27_RS18100	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
WU27_RS18115	COG0617	tRNA 3'-terminal CCA addition
WU27_RS18140	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
WU27_RS18145	COG2188	Transcriptional regulator
WU27_RS18155	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WU27_RS18165	COG1028	Short-chain dehydrogenase reductase Sdr
WU27_RS18195	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WU27_RS18200	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
WU27_RS18205	COG1012	belongs to the aldehyde dehydrogenase family
WU27_RS18230	COG4257	antibiotic catabolic process
WU27_RS18240	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
WU27_RS18245	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
WU27_RS18255	COG1250	3-hydroxyacyl-CoA dehydrogenase
WU27_RS18260	COG2031	fatty acid transporter
WU27_RS18265	COG1028	Short-chain dehydrogenase reductase Sdr
WU27_RS18270	COG1414	Transcriptional regulator
WU27_RS18280	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
WU27_RS18295	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
WU27_RS18335	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
WU27_RS18335	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
WU27_RS18340	COG0509	glycine decarboxylation via glycine cleavage system
WU27_RS18345	COG0404	The glycine cleavage system catalyzes the degradation of glycine
WU27_RS18355	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
WU27_RS18365	COG2081	HI0933 family
WU27_RS18395	COG0717	Belongs to the dCTP deaminase family
WU27_RS18410	COG0489	protein tyrosine kinase activity
WU27_RS18420	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WU27_RS18420	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WU27_RS18425	COG1054	Belongs to the UPF0176 family
WU27_RS18460	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
WU27_RS18465	COG1280	lysine exporter protein (LysE YggA)
WU27_RS18470	COG0513	Belongs to the DEAD box helicase family
WU27_RS18480	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
WU27_RS18500	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
WU27_RS18515	COG2226	methyltransferase
WU27_RS18520	COG0745	RESPONSE REGULATOR receiver
WU27_RS18525	COG5002	protein histidine kinase activity
WU27_RS18535	COG5002	protein histidine kinase activity
WU27_RS18545	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
WU27_RS18550	COG0583	DNA-binding transcription factor activity
WU27_RS18560	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
WU27_RS18565	COG1984	allophanate hydrolase subunit 2
WU27_RS18580	COG3181	Tripartite tricarboxylate transporter family receptor
WU27_RS18595	COG1024	Enoyl-CoA hydratase
WU27_RS18610	COG1802	Transcriptional regulator
WU27_RS18625	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
WU27_RS18630	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WU27_RS18645	COG0583	DNA-binding transcription factor activity
WU27_RS18655	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
WU27_RS18665	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
WU27_RS18670	COG0154	amidase activity
WU27_RS18680	COG1609	Transcriptional regulator
WU27_RS18700	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
WU27_RS18710	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
WU27_RS18715	COG3842	ATPase activity
WU27_RS18720	COG1653	transport
WU27_RS18725	COG1175	transmembrane transport
WU27_RS18730	COG0395	ABC-type sugar transport system, permease component
WU27_RS18750	COG0018	arginyl-trna synthetase
WU27_RS18760	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
WU27_RS18795	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
WU27_RS18800	COG0321	lipoyl(octanoyl) transferase activity
WU27_RS18805	COG2921	Belongs to the UPF0250 family
WU27_RS18815	COG1686	Belongs to the peptidase S11 family
WU27_RS18835	COG1127	ABC transporter
WU27_RS18840	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
WU27_RS18850	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
WU27_RS18865	COG0859	PFAM glycosyl transferase family 9
WU27_RS18895	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
WU27_RS18900	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
WU27_RS18905	COG0438	transferase activity, transferring glycosyl groups
WU27_RS18935	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
WU27_RS18940	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
WU27_RS18955	COG0625	glutathione transferase activity
WU27_RS18960	COG0326	Molecular chaperone. Has ATPase activity
WU27_RS18990	COG1652	LysM domain
WU27_RS19005	COG0220	tRNA (guanine-N7-)-methyltransferase activity
WU27_RS19020	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
WU27_RS19050	COG3181	Tripartite tricarboxylate transporter family receptor
WU27_RS19065	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WU27_RS19080	COG1024	Enoyl-CoA hydratase
WU27_RS19095	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU27_RS19100	COG1309	transcriptional regulator
WU27_RS19105	COG2816	NAD+ diphosphatase activity
WU27_RS19110	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WU27_RS19195	COG2814	Major facilitator Superfamily
WU27_RS19200	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
WU27_RS19220	COG1999	signal sequence binding
WU27_RS19225	COG0109	protoheme IX farnesyltransferase activity
WU27_RS19265	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
WU27_RS19285	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
WU27_RS19290	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
WU27_RS19300	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
WU27_RS19305	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
WU27_RS19315	COG0069	glutamate synthase activity
WU27_RS19315	COG0070	glutamate synthase
WU27_RS19315	COG0067	glutamate synthase
WU27_RS19325	COG3047	cAMP biosynthetic process
WU27_RS19335	COG1127	ABC transporter
WU27_RS19340	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
WU27_RS19345	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
WU27_RS19350	COG2853	Lipoprotein
WU27_RS19360	COG1131	(ABC) transporter
WU27_RS19365	COG0842	Transport permease protein
WU27_RS19375	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
WU27_RS19380	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
WU27_RS19385	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
WU27_RS19390	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
WU27_RS19395	COG0131	Imidazoleglycerol-phosphate dehydratase
WU27_RS19400	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
WU27_RS19405	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
WU27_RS19410	COG0107	imidazoleglycerol-phosphate synthase activity
WU27_RS19415	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
WU27_RS19420	COG0140	phosphoribosyl-ATP diphosphatase activity
WU27_RS19425	COG0537	adenosine 5'-monophosphoramidase activity
WU27_RS19430	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
WU27_RS19435	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
WU27_RS19450	COG3181	Tripartite tricarboxylate transporter family receptor
WU27_RS19485	COG3702	type iv secretory pathway
WU27_RS19490	COG3451	type IV secretory pathway VirB4
WU27_RS19505	COG3736	Type IV secretory pathway, component VirB8
WU27_RS19510	COG3504	Conjugal transfer protein
WU27_RS19515	COG2948	multi-organism process
WU27_RS19520	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
WU27_RS19530	COG0697	spore germination
WU27_RS19550	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
WU27_RS19555	COG0747	negative chemotaxis
WU27_RS19560	COG0601	transmembrane transport
WU27_RS19565	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WU27_RS19570	COG0444	Belongs to the ABC transporter superfamily
WU27_RS19580	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
WU27_RS19590	COG0494	nUDIX hydrolase
WU27_RS19630	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
WU27_RS19635	COG0237	dephospho-CoA kinase activity
WU27_RS19640	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
WU27_RS19655	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
WU27_RS19660	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
WU27_RS19670	COG0477	Major facilitator Superfamily
WU27_RS19675	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
WU27_RS19690	COG1126	abc transporter atp-binding protein
WU27_RS19695	COG0765	amino acid transport
WU27_RS19700	COG4597	amino acid ABC transporter
WU27_RS19705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WU27_RS19710	COG2884	Cell division ATP-binding protein ftsE
WU27_RS19715	COG2177	Part of the ABC transporter FtsEX involved in
WU27_RS19720	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
WU27_RS19730	COG1194	a g-specific adenine glycosylase
WU27_RS19740	COG2226	methyltransferase
WU27_RS19750	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU27_RS19755	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU27_RS19770	COG1024	Enoyl-CoA hydratase
WU27_RS19790	COG1024	Enoyl-CoA hydratase
WU27_RS19795	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WU27_RS19800	COG3181	Tripartite tricarboxylate transporter family receptor
WU27_RS19810	COG0753	catalase activity
WU27_RS19815	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WU27_RS19820	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
WU27_RS19830	COG2175	clavaminate synthase activity
WU27_RS19835	COG1473	amidohydrolase
WU27_RS19840	COG4608	Belongs to the ABC transporter superfamily
WU27_RS19845	COG0444	Belongs to the ABC transporter superfamily
WU27_RS19860	COG0747	negative chemotaxis
WU27_RS19865	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
WU27_RS19900	COG0436	Aminotransferase
WU27_RS19905	COG1278	Cold shock