locus-tag	class	description
CX034_RS00005	COG0445	tRNA wobble uridine modification
CX034_RS00010	COG0357	Ribosomal RNA small subunit methyltransferase G
CX034_RS00015	COG1192	Involved in chromosome partitioning
CX034_RS00025	COG1475	DNA binding
CX034_RS00050	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CX034_RS00060	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CX034_RS00070	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CX034_RS00075	COG0081	regulation of translation
CX034_RS00080	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CX034_RS00085	COG0222	ribosome binding
CX034_RS00090	COG0085	RNA polymerase activity
CX034_RS00095	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CX034_RS00135	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX034_RS00160	COG1024	Enoyl-CoA hydratase
CX034_RS00180	COG0752	glycyl-tRNA synthetase alpha subunit
CX034_RS00185	COG0751	glycine-tRNA ligase activity
CX034_RS00190	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CX034_RS00195	COG0204	Acyl-transferase
CX034_RS00210	COG0242	peptide deformylase activity
CX034_RS00250	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CX034_RS00255	COG2813	Specifically methylates the guanine in position
CX034_RS00255	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CX034_RS00270	COG2223	nitrite transmembrane transporter activity
CX034_RS00280	COG1794	racemase activity, acting on amino acids and derivatives
CX034_RS00285	COG1126	abc transporter atp-binding protein
CX034_RS00290	COG0765	amino acid transport
CX034_RS00295	COG0765	amino acid transport
CX034_RS00300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CX034_RS00365	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CX034_RS00395	COG0326	Molecular chaperone. Has ATPase activity
CX034_RS00400	COG0625	glutathione transferase activity
CX034_RS00415	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CX034_RS00420	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CX034_RS00450	COG0438	transferase activity, transferring glycosyl groups
CX034_RS00455	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CX034_RS00460	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CX034_RS00490	COG0859	PFAM glycosyl transferase family 9
CX034_RS00505	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CX034_RS00515	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CX034_RS00520	COG1127	ABC transporter
CX034_RS00540	COG1686	Belongs to the peptidase S11 family
CX034_RS00550	COG2921	Belongs to the UPF0250 family
CX034_RS00555	COG0321	lipoyl(octanoyl) transferase activity
CX034_RS00560	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CX034_RS00595	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CX034_RS00605	COG0018	arginyl-trna synthetase
CX034_RS00625	COG0395	ABC-type sugar transport system, permease component
CX034_RS00630	COG1175	transmembrane transport
CX034_RS00635	COG1653	transport
CX034_RS00640	COG3842	ATPase activity
CX034_RS00645	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CX034_RS00655	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CX034_RS00675	COG1609	Transcriptional regulator
CX034_RS00685	COG0154	amidase activity
CX034_RS00690	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CX034_RS00700	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CX034_RS00710	COG0583	DNA-binding transcription factor activity
CX034_RS00730	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CX034_RS00745	COG1802	Transcriptional regulator
CX034_RS00760	COG1024	Enoyl-CoA hydratase
CX034_RS00770	COG3181	Tripartite tricarboxylate transporter family receptor
CX034_RS00785	COG1984	allophanate hydrolase subunit 2
CX034_RS00790	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CX034_RS00800	COG0583	DNA-binding transcription factor activity
CX034_RS00805	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CX034_RS00815	COG5002	protein histidine kinase activity
CX034_RS00825	COG5002	protein histidine kinase activity
CX034_RS00830	COG0745	RESPONSE REGULATOR receiver
CX034_RS00835	COG2226	methyltransferase
CX034_RS00850	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CX034_RS00870	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CX034_RS00880	COG0513	Belongs to the DEAD box helicase family
CX034_RS00885	COG1280	lysine exporter protein (LysE YggA)
CX034_RS00890	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CX034_RS00930	COG1054	Belongs to the UPF0176 family
CX034_RS00935	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CX034_RS00935	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CX034_RS00945	COG0489	protein tyrosine kinase activity
CX034_RS00960	COG0717	Belongs to the dCTP deaminase family
CX034_RS00990	COG2081	HI0933 family
CX034_RS01000	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CX034_RS01010	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CX034_RS01015	COG0509	glycine decarboxylation via glycine cleavage system
CX034_RS01020	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CX034_RS01020	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CX034_RS01060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CX034_RS01075	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CX034_RS01085	COG1414	Transcriptional regulator
CX034_RS01090	COG1028	Short-chain dehydrogenase reductase Sdr
CX034_RS01095	COG2031	fatty acid transporter
CX034_RS01100	COG1250	3-hydroxyacyl-CoA dehydrogenase
CX034_RS01110	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CX034_RS01115	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CX034_RS01125	COG4257	antibiotic catabolic process
CX034_RS01150	COG1012	belongs to the aldehyde dehydrogenase family
CX034_RS01155	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CX034_RS01160	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CX034_RS01185	COG1028	Short-chain dehydrogenase reductase Sdr
CX034_RS01195	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CX034_RS01205	COG2188	Transcriptional regulator
CX034_RS01210	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CX034_RS01235	COG0617	tRNA 3'-terminal CCA addition
CX034_RS01250	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CX034_RS01255	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CX034_RS01260	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CX034_RS01265	COG0586	Pfam SNARE associated Golgi protein
CX034_RS01270	COG0860	N-Acetylmuramoyl-L-alanine amidase
CX034_RS01275	COG0802	atpase or kinase
CX034_RS01280	COG0114	fumarate hydratase activity
CX034_RS01290	COG3181	Tripartite tricarboxylate transporter family receptor
CX034_RS01300	COG0405	Gamma-glutamyltransferase
CX034_RS01305	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX034_RS01340	COG1294	oxidase, subunit
CX034_RS01350	COG4988	ABC transporter
CX034_RS01355	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CX034_RS01405	COG2969	positive regulation of protein catabolic process
CX034_RS01410	COG0625	glutathione transferase activity
CX034_RS01415	COG2857	Cytochrome c1
CX034_RS01420	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CX034_RS01425	COG0723	plastoquinol--plastocyanin reductase activity
CX034_RS01430	COG1970	mechanosensitive ion channel activity
CX034_RS01435	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CX034_RS01450	COG2808	Putative FMN-binding domain
CX034_RS01455	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CX034_RS01460	COG0747	negative chemotaxis
CX034_RS01465	COG0657	acetylesterase activity
CX034_RS01475	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CX034_RS01480	COG2207	Transcriptional regulator
CX034_RS01485	COG0129	dihydroxy-acid dehydratase activity
CX034_RS01490	COG2814	Major facilitator Superfamily
CX034_RS01495	COG0583	DNA-binding transcription factor activity
CX034_RS01505	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
CX034_RS01575	COG1024	Enoyl-CoA hydratase
CX034_RS01580	COG1960	acyl-CoA dehydrogenase activity
CX034_RS01605	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CX034_RS01610	COG0352	thiamine-phosphate diphosphorylase activity
CX034_RS01625	COG1678	Uncharacterized ACR, COG1678
CX034_RS01630	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CX034_RS01635	COG0540	Belongs to the ATCase OTCase family
CX034_RS01650	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CX034_RS01660	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CX034_RS01695	COG1234	tRNA 3'-trailer cleavage
CX034_RS01715	COG3064	Membrane
CX034_RS01745	COG1683	Conserved Protein
CX034_RS01750	COG1120	ATPase activity
CX034_RS01755	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CX034_RS01760	COG4558	Periplasmic binding protein
CX034_RS01765	COG3720	iron ion transport
CX034_RS01775	COG3712	iron ion homeostasis
CX034_RS01780	COG1595	DNA-templated transcription, initiation
CX034_RS01815	COG1802	Transcriptional regulator
CX034_RS01825	COG3069	C4-dicarboxylate transmembrane transporter activity
CX034_RS01835	COG1012	belongs to the aldehyde dehydrogenase family
CX034_RS01870	COG2860	membrane
CX034_RS01875	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CX034_RS01880	COG0708	Exodeoxyribonuclease III
CX034_RS01885	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CX034_RS01890	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CX034_RS01895	COG0154	amidase activity
CX034_RS01900	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CX034_RS01905	COG1077	Cell shape determining protein MreB Mrl
CX034_RS01910	COG1792	Involved in formation and maintenance of cell shape
CX034_RS01920	COG0768	penicillin binding
CX034_RS01925	COG0772	Belongs to the SEDS family
CX034_RS01930	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CX034_RS01935	COG0471	metal ion transport
CX034_RS01940	COG1309	transcriptional regulator
CX034_RS01950	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CX034_RS01965	COG2823	Periplasmic or secreted lipoprotein
CX034_RS01970	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CX034_RS01985	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CX034_RS02005	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX034_RS02015	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX034_RS02035	COG0492	ferredoxin-NADP+ reductase activity
CX034_RS02045	COG3181	Tripartite tricarboxylate transporter family receptor
CX034_RS02050	COG1250	3-hydroxyacyl-CoA dehydrogenase
CX034_RS02050	COG1024	Enoyl-CoA hydratase
CX034_RS02055	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX034_RS02060	COG0028	Belongs to the TPP enzyme family
CX034_RS02085	COG3181	Tripartite tricarboxylate transporter family receptor
CX034_RS02100	COG0697	spore germination
CX034_RS02130	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CX034_RS02135	COG0463	Glycosyl transferase, family 2
CX034_RS02150	COG0786	glutamate:sodium symporter activity
CX034_RS02160	COG2031	fatty acid transporter
CX034_RS02175	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CX034_RS02205	COG3181	Tripartite tricarboxylate transporter family receptor
CX034_RS02215	COG0277	FAD linked oxidase domain protein
CX034_RS02220	COG1960	acyl-CoA dehydrogenase activity
CX034_RS02225	COG1960	acyl-CoA dehydrogenase activity
CX034_RS02235	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CX034_RS02250	COG2072	flavoprotein involved in K transport
CX034_RS02255	COG0604	alcohol dehydrogenase
CX034_RS02270	COG1024	Enoyl-CoA hydratase
CX034_RS02290	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CX034_RS02295	COG1522	sequence-specific DNA binding
CX034_RS02300	COG0183	Belongs to the thiolase family
CX034_RS02310	COG1960	acyl-CoA dehydrogenase activity
CX034_RS02350	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CX034_RS02355	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CX034_RS02360	COG2890	protein-(glutamine-N5) methyltransferase activity
CX034_RS02365	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CX034_RS02375	COG3181	Tripartite tricarboxylate transporter family receptor
CX034_RS02410	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CX034_RS02415	COG1660	Displays ATPase and GTPase activities
CX034_RS02425	COG2010	Cytochrome c
CX034_RS02425	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CX034_RS02430	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CX034_RS02445	COG1137	ATPase activity
CX034_RS02460	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CX034_RS02470	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CX034_RS02505	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CX034_RS02510	COG3568	Endonuclease Exonuclease Phosphatase
CX034_RS02515	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CX034_RS02545	COG0154	amidase activity
CX034_RS02555	COG1414	Transcriptional regulator
CX034_RS02565	COG1250	3-hydroxyacyl-CoA dehydrogenase
CX034_RS02565	COG1024	Enoyl-CoA hydratase
CX034_RS02575	COG2132	Multicopper oxidase
CX034_RS02630	COG1024	Enoyl-CoA hydratase
CX034_RS02635	COG1024	Enoyl-CoA hydratase
CX034_RS02640	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CX034_RS02660	COG0601	transmembrane transport
CX034_RS02665	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CX034_RS02670	COG4172	Belongs to the ABC transporter superfamily
CX034_RS02680	COG2195	Cleaves the N-terminal amino acid of tripeptides
CX034_RS02690	COG0210	DNA helicase
CX034_RS02695	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CX034_RS02700	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CX034_RS02710	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CX034_RS02715	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CX034_RS02720	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CX034_RS02725	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CX034_RS02730	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CX034_RS02735	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CX034_RS02745	COG0356	it plays a direct role in the translocation of protons across the membrane
CX034_RS02770	COG1024	Enoyl-CoA hydratase
CX034_RS02775	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CX034_RS02780	COG3634	alkyl hydroperoxide reductase activity
CX034_RS02790	COG0037	tRNA processing
CX034_RS02800	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CX034_RS02805	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CX034_RS02810	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CX034_RS02815	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CX034_RS02820	COG2967	ApaG domain
CX034_RS02825	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CX034_RS02830	COG0546	phosphoglycolate phosphatase activity
CX034_RS02840	COG0512	Glutamine amidotransferase of anthranilate synthase
CX034_RS02845	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CX034_RS02850	COG0134	indole-3-glycerol-phosphate synthase activity
CX034_RS02875	COG0583	DNA-binding transcription factor activity
CX034_RS02890	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CX034_RS02895	COG0259	pyridoxamine-phosphate oxidase activity
CX034_RS02905	COG2814	Major facilitator Superfamily
CX034_RS02910	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CX034_RS02915	COG2188	Transcriptional regulator
CX034_RS02920	COG0318	PFAM AMP-dependent synthetase and ligase
CX034_RS02940	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CX034_RS02950	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CX034_RS02965	COG1215	transferase activity, transferring glycosyl groups
CX034_RS02975	COG0601	transmembrane transport
CX034_RS03010	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CX034_RS03015	COG2894	cell division
CX034_RS03020	COG0850	regulation of cytokinetic process
CX034_RS03025	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CX034_RS03030	COG1271	oxidase subunit
CX034_RS03065	COG2979	Protein of unknown function (DUF533)
CX034_RS03085	COG0741	lytic transglycosylase activity
CX034_RS03085	COG1388	LysM domain
CX034_RS03090	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CX034_RS03095	COG2226	methyltransferase
CX034_RS03100	COG0328	RNA-DNA hybrid ribonuclease activity
CX034_RS03150	COG2030	dehydratase
CX034_RS03200	COG1960	acyl-CoA dehydrogenase activity
CX034_RS03215	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX034_RS03235	COG2718	Belongs to the UPF0229 family
CX034_RS03240	COG2719	SpoVR family
CX034_RS03265	COG2188	Transcriptional regulator
CX034_RS03295	COG0829	nickel cation binding
CX034_RS03300	COG0831	urea catabolic process
CX034_RS03310	COG0832	Belongs to the urease beta subunit family
CX034_RS03315	COG0804	urea catabolic process
CX034_RS03325	COG0830	nickel cation binding
CX034_RS03330	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CX034_RS03350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CX034_RS03355	COG0601	transmembrane transport
CX034_RS03360	COG0747	negative chemotaxis
CX034_RS03370	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CX034_RS03375	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CX034_RS03385	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CX034_RS03395	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
CX034_RS03400	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CX034_RS03405	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CX034_RS03420	COG0438	transferase activity, transferring glycosyl groups
CX034_RS03435	COG0438	transferase activity, transferring glycosyl groups
CX034_RS03440	COG0438	transferase activity, transferring glycosyl groups
CX034_RS03445	COG0166	Belongs to the GPI family
CX034_RS03460	COG0277	FAD linked oxidase domain protein
CX034_RS03465	COG0745	RESPONSE REGULATOR receiver
CX034_RS03470	COG0642	Histidine kinase
CX034_RS03475	COG1368	sulfuric ester hydrolase activity
CX034_RS03485	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CX034_RS03510	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CX034_RS03520	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CX034_RS03525	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CX034_RS03535	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CX034_RS03540	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CX034_RS03545	COG0193	aminoacyl-tRNA hydrolase activity
CX034_RS03555	COG0012	GTP binding
CX034_RS03560	COG0582	viral genome integration into host DNA
CX034_RS03585	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CX034_RS03650	COG0745	RESPONSE REGULATOR receiver
CX034_RS03665	COG1309	transcriptional regulator
CX034_RS03695	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CX034_RS03705	COG0405	Gamma-glutamyltransferase
CX034_RS03780	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CX034_RS03785	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CX034_RS03795	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CX034_RS03800	COG0513	Belongs to the DEAD box helicase family
CX034_RS03810	COG0617	tRNA 3'-terminal CCA addition
CX034_RS03825	COG0477	Major facilitator Superfamily
CX034_RS03835	COG0583	DNA-binding transcription factor activity
CX034_RS03850	COG1950	PFAM Membrane protein of
CX034_RS03855	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CX034_RS03870	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CX034_RS03880	COG1560	Kdo2-lipid A biosynthetic process
CX034_RS03885	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CX034_RS03895	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CX034_RS03905	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CX034_RS03915	COG0803	Belongs to the bacterial solute-binding protein 9 family
CX034_RS03930	COG0735	belongs to the Fur family
CX034_RS03935	COG0523	cobalamin synthesis protein
CX034_RS03945	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CX034_RS03950	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CX034_RS03965	COG2096	Adenosyltransferase
CX034_RS03985	COG2084	Dehydrogenase
CX034_RS04035	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CX034_RS04040	COG0129	dihydroxy-acid dehydratase activity
CX034_RS04045	COG4654	Cytochrome c, class I
CX034_RS04050	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CX034_RS04100	COG1473	amidohydrolase
CX034_RS04105	COG0418	dihydroorotase activity
CX034_RS04110	COG0488	(ABC) transporter
CX034_RS04120	COG2001	Belongs to the MraZ family
CX034_RS04125	COG0275	rRNA processing
CX034_RS04130	COG3116	cell division
CX034_RS04140	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CX034_RS04145	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CX034_RS04150	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CX034_RS04160	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CX034_RS04165	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CX034_RS04170	COG1181	Belongs to the D-alanine--D-alanine ligase family
CX034_RS04175	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CX034_RS04185	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CX034_RS04190	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CX034_RS04200	COG0739	heme binding
CX034_RS04205	COG0653	protein targeting
CX034_RS04225	COG1028	Short-chain dehydrogenase reductase Sdr
CX034_RS04230	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CX034_RS04235	COG1522	sequence-specific DNA binding
CX034_RS04255	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CX034_RS04265	COG0557	exoribonuclease II activity
CX034_RS04270	COG3150	esterase
CX034_RS04275	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CX034_RS04280	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CX034_RS04285	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CX034_RS04290	COG0511	ligase activity, forming carbon-carbon bonds
CX034_RS04295	COG0439	Biotin carboxylase
CX034_RS04310	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CX034_RS04335	COG1696	Membrane protein involved in D-alanine export
CX034_RS04340	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CX034_RS04375	COG1522	sequence-specific DNA binding
CX034_RS04390	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CX034_RS04395	COG0045	succinate-CoA ligase (ADP-forming) activity
CX034_RS04395	COG1042	CoA-binding domain protein
CX034_RS04395	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CX034_RS04410	COG1802	Transcriptional regulator
CX034_RS04415	COG3069	C4-dicarboxylate transmembrane transporter activity
CX034_RS04420	COG0513	Belongs to the DEAD box helicase family
CX034_RS04425	COG0346	lactoylglutathione lyase activity
CX034_RS04430	COG1335	isochorismatase
CX034_RS04435	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CX034_RS04440	COG1116	anion transmembrane transporter activity
CX034_RS04455	COG3028	Belongs to the UPF0307 family
CX034_RS04460	COG0312	modulator of DNA gyrase
CX034_RS04465	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CX034_RS04470	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CX034_RS04475	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CX034_RS04480	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CX034_RS04490	COG0316	Belongs to the HesB IscA family
CX034_RS04495	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CX034_RS04510	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CX034_RS04520	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CX034_RS04525	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CX034_RS04540	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CX034_RS04540	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CX034_RS04575	COG0583	DNA-binding transcription factor activity
CX034_RS04580	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX034_RS04615	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CX034_RS04625	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CX034_RS04630	COG1845	cytochrome c oxidase, subunit III
CX034_RS04635	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CX034_RS04640	COG0640	Transcriptional regulator
CX034_RS04660	COG3220	belongs to the UPF0276 family
CX034_RS04705	COG1666	GTP binding
CX034_RS04740	COG0312	modulator of DNA gyrase
CX034_RS04745	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CX034_RS04750	COG3210	domain, Protein
CX034_RS04750	COG3064	Membrane
CX034_RS04750	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CX034_RS04750	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CX034_RS04750	COG3210	domain, Protein
CX034_RS04750	COG3064	Membrane
CX034_RS04755	COG0277	FAD linked oxidase domain protein
CX034_RS04760	COG0277	FAD linked oxidase domain protein
CX034_RS04765	COG0277	FAD linked oxidase domain protein
CX034_RS04770	COG0247	lactate metabolic process
CX034_RS04775	COG2819	hydrolase of the alpha beta superfamily
CX034_RS04815	COG0583	DNA-binding transcription factor activity
CX034_RS04820	COG0482	sulfurtransferase activity
CX034_RS04825	COG0730	response to heat
CX034_RS04830	COG0625	glutathione transferase activity
CX034_RS04835	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CX034_RS04840	COG3909	cytochrome
CX034_RS04880	COG0154	amidase activity
CX034_RS04885	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX034_RS04890	COG1024	Enoyl-CoA hydratase
CX034_RS04905	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CX034_RS04920	COG1028	Short-chain dehydrogenase reductase Sdr
CX034_RS04925	COG1414	Transcriptional regulator
CX034_RS04935	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CX034_RS04940	COG0251	oxidation-reduction process
CX034_RS04945	COG0559	Belongs to the binding-protein-dependent transport system permease family
CX034_RS04980	COG0583	DNA-binding transcription factor activity
CX034_RS04990	COG0590	tRNA wobble adenosine to inosine editing
CX034_RS04995	COG2807	transmembrane transport
CX034_RS05015	COG0154	amidase activity
CX034_RS05020	COG0307	riboflavin synthase, alpha
CX034_RS05025	COG3181	Tripartite tricarboxylate transporter family receptor
CX034_RS05030	COG1522	sequence-specific DNA binding
CX034_RS05040	COG0318	PFAM AMP-dependent synthetase and ligase
CX034_RS05050	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CX034_RS05070	COG1063	alcohol dehydrogenase
CX034_RS05095	COG1418	mRNA catabolic process
CX034_RS05100	COG1448	Aminotransferase
CX034_RS05105	COG0583	DNA-binding transcription factor activity
CX034_RS05115	COG0477	Major facilitator Superfamily
CX034_RS05120	COG1028	Short-chain dehydrogenase reductase Sdr
CX034_RS05135	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CX034_RS05140	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CX034_RS05145	COG0583	DNA-binding transcription factor activity
CX034_RS05205	COG1028	Short-chain dehydrogenase reductase Sdr
CX034_RS05210	COG1309	transcriptional regulator
CX034_RS05220	COG2982	Protein involved in outer membrane biogenesis
CX034_RS05225	COG2818	Glycosylase
CX034_RS05245	COG1653	transport
CX034_RS05260	COG3842	ATPase activity
CX034_RS05265	COG0395	ABC-type sugar transport system, permease component
CX034_RS05270	COG1175	transmembrane transport
CX034_RS05290	COG3181	Tripartite tricarboxylate transporter family receptor
CX034_RS05295	COG2186	Transcriptional regulator
CX034_RS05325	COG1454	alcohol dehydrogenase
CX034_RS05345	COG2011	ABC-type metal ion transport system permease component
CX034_RS05350	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CX034_RS05355	COG1501	Belongs to the glycosyl hydrolase 31 family
CX034_RS05380	COG0318	PFAM AMP-dependent synthetase and ligase
CX034_RS05385	COG1473	amidohydrolase
CX034_RS05395	COG2855	membrane
CX034_RS05405	COG2239	Acts as a magnesium transporter
CX034_RS05425	COG3181	Tripartite tricarboxylate transporter family receptor
CX034_RS05435	COG1722	exodeoxyribonuclease VII activity
CX034_RS05440	COG0142	geranyltranstransferase activity
CX034_RS05445	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CX034_RS05450	COG1469	GTP cyclohydrolase I activity
CX034_RS05455	COG0360	Binds together with S18 to 16S ribosomal RNA
CX034_RS05460	COG2965	DNA replication, synthesis of RNA primer
CX034_RS05465	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CX034_RS05470	COG0359	binds to the 23S rRNA
CX034_RS05480	COG0305	Participates in initiation and elongation during chromosome replication
CX034_RS05490	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CX034_RS05495	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CX034_RS05500	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CX034_RS05505	COG3737	Protein of unknown function (DUF498/DUF598)
CX034_RS05510	COG0436	Aminotransferase
CX034_RS05535	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CX034_RS05570	COG0268	Binds directly to 16S ribosomal RNA
CX034_RS05580	COG0728	peptidoglycan biosynthetic process
CX034_RS05590	COG0563	adenylate kinase activity
CX034_RS05595	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CX034_RS05600	COG2835	tetraacyldisaccharide 4'-kinase activity
CX034_RS05605	COG1663	tetraacyldisaccharide 4'-kinase activity
CX034_RS05610	COG0848	biopolymer transport protein
CX034_RS05615	COG0811	peptide transport
CX034_RS05625	COG1570	exodeoxyribonuclease VII activity
CX034_RS05630	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CX034_RS05635	COG0038	chloride channel
CX034_RS05640	COG0183	Belongs to the thiolase family
CX034_RS05650	COG1278	Cold shock
CX034_RS05655	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CX034_RS05665	COG4953	penicillin-binding protein 1C
CX034_RS05670	COG0542	response to heat
CX034_RS05675	COG2995	paraquat-inducible protein a
CX034_RS05680	COG3008	intermembrane lipid transfer
CX034_RS05680	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CX034_RS05690	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CX034_RS05690	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CX034_RS05690	COG0506	proline dehydrogenase activity
CX034_RS05725	COG2271	Major facilitator Superfamily
CX034_RS05730	COG1309	transcriptional regulator
CX034_RS05765	COG0477	Major facilitator Superfamily
CX034_RS05775	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CX034_RS05780	COG1845	cytochrome c oxidase, subunit III
CX034_RS05785	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CX034_RS05795	COG1028	Short-chain dehydrogenase reductase Sdr
CX034_RS05815	COG0789	Transcriptional regulator
CX034_RS05840	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CX034_RS05845	COG0697	spore germination
CX034_RS05855	COG0678	peroxiredoxin activity
CX034_RS05865	COG0412	Dienelactone hydrolase
CX034_RS05875	COG0315	cyclic pyranopterin monophosphate synthase activity
CX034_RS05890	COG0521	Mo-molybdopterin cofactor biosynthetic process
CX034_RS05895	COG0303	'Molybdopterin
CX034_RS05900	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CX034_RS05920	COG0165	Argininosuccinate lyase
CX034_RS05925	COG0668	transmembrane transport
CX034_RS05970	COG0747	negative chemotaxis
CX034_RS05975	COG0601	transmembrane transport
CX034_RS05990	COG1162	GTPase activity
CX034_RS05995	COG0501	Belongs to the peptidase M48B family
CX034_RS06000	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CX034_RS06010	COG3327	negative regulation of DNA-templated transcription, initiation
CX034_RS06015	COG3396	Phenylacetate-CoA oxygenase
CX034_RS06020	COG3460	Phenylacetate-CoA oxygenase
CX034_RS06025	COG3396	Phenylacetate-CoA oxygenase
CX034_RS06030	COG2151	metal-sulfur cluster biosynthetic enzyme
CX034_RS06050	COG1012	belongs to the aldehyde dehydrogenase family
CX034_RS06055	COG1024	Enoyl-CoA hydratase
CX034_RS06060	COG2050	protein possibly involved in aromatic compounds catabolism
CX034_RS06070	COG3539	Fimbrial protein
CX034_RS06090	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CX034_RS06095	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CX034_RS06095	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CX034_RS06100	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CX034_RS06105	COG0047	phosphoribosylformylglycinamidine synthase activity
CX034_RS06105	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CX034_RS06110	COG3210	domain, Protein
CX034_RS06110	COG3064	Membrane
CX034_RS06110	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CX034_RS06140	COG0235	Class ii aldolase
CX034_RS06145	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CX034_RS06150	COG0720	synthase
CX034_RS06155	COG0602	queuosine metabolic process
CX034_RS06180	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CX034_RS06215	COG3181	Tripartite tricarboxylate transporter family receptor
CX034_RS06240	COG3842	ATPase activity
CX034_RS06250	COG0395	ABC-type sugar transport system, permease component
CX034_RS06280	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CX034_RS06285	COG0420	3'-5' exonuclease activity
CX034_RS06330	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CX034_RS06330	COG0519	Catalyzes the synthesis of GMP from XMP
CX034_RS06345	COG3550	peptidyl-serine autophosphorylation
CX034_RS06355	COG0477	Major facilitator Superfamily
CX034_RS06370	COG1228	amidohydrolase
CX034_RS06380	COG1116	anion transmembrane transporter activity
CX034_RS06385	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CX034_RS06430	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CX034_RS06450	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CX034_RS06480	COG2814	Major facilitator Superfamily
CX034_RS06495	COG1280	lysine exporter protein (LysE YggA)
CX034_RS06515	COG0747	negative chemotaxis
CX034_RS06520	COG0601	transmembrane transport
CX034_RS06525	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CX034_RS06530	COG4172	Belongs to the ABC transporter superfamily
CX034_RS06535	COG1609	Transcriptional regulator
CX034_RS06565	COG0586	Pfam SNARE associated Golgi protein
CX034_RS06580	COG0500	methyltransferase
CX034_RS06595	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CX034_RS06605	COG0756	dUTP diphosphatase activity
CX034_RS06615	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CX034_RS06620	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CX034_RS06625	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CX034_RS06630	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CX034_RS06630	COG0072	phenylalanine-tRNA ligase activity
CX034_RS06635	COG0776	regulation of translation
CX034_RS06700	COG0540	Belongs to the ATCase OTCase family
CX034_RS06705	COG2974	May be involved in recombination
CX034_RS06715	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX034_RS06720	COG0583	DNA-binding transcription factor activity
CX034_RS06740	COG1028	Short-chain dehydrogenase reductase Sdr
CX034_RS06755	COG3842	ATPase activity
CX034_RS06760	COG1250	3-hydroxyacyl-CoA dehydrogenase
CX034_RS06760	COG1024	Enoyl-CoA hydratase
CX034_RS06780	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CX034_RS06785	COG2137	regulation of response to DNA damage stimulus
CX034_RS06795	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CX034_RS06805	COG0045	succinate-CoA ligase (ADP-forming) activity
CX034_RS06810	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CX034_RS06815	COG0861	Integral membrane protein TerC family
CX034_RS06820	COG0861	Integral membrane protein TerC family
CX034_RS06825	COG0181	hydroxymethylbilane synthase activity
CX034_RS06885	COG4964	Belongs to the GSP D family
CX034_RS06910	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CX034_RS06920	COG0583	DNA-binding transcription factor activity
CX034_RS06930	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CX034_RS06935	COG4311	Sarcosine oxidase, delta subunit
CX034_RS06940	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CX034_RS06940	COG0446	pyridine nucleotide-disulphide oxidoreductase
CX034_RS06975	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CX034_RS06980	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CX034_RS06985	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CX034_RS06990	COG0735	belongs to the Fur family
CX034_RS06995	COG0497	DNA recombination
CX034_RS07000	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CX034_RS07005	COG1420	regulation of RNA biosynthetic process
CX034_RS07010	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CX034_RS07020	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CX034_RS07030	COG0443	Heat shock 70 kDa protein
CX034_RS07040	COG0612	Peptidase, M16
CX034_RS07060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CX034_RS07105	COG0745	RESPONSE REGULATOR receiver
CX034_RS07115	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CX034_RS07120	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CX034_RS07125	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CX034_RS07140	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CX034_RS07160	COG1193	negative regulation of DNA recombination
CX034_RS07165	COG0492	ferredoxin-NADP+ reductase activity
CX034_RS07170	COG1674	ftsk spoiiie
CX034_RS07175	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CX034_RS07180	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CX034_RS07185	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CX034_RS07210	COG3706	GGDEF domain
CX034_RS07230	COG2814	Major facilitator Superfamily
CX034_RS07260	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CX034_RS07275	COG1028	Short-chain dehydrogenase reductase Sdr
CX034_RS07285	COG3022	response to hydroperoxide
CX034_RS07325	COG2197	response regulator
CX034_RS07330	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CX034_RS07335	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CX034_RS07340	COG0189	ligase activity
CX034_RS07350	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CX034_RS07355	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CX034_RS07370	COG2423	ornithine cyclodeaminase activity
CX034_RS07380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CX034_RS07385	COG0765	amino acid transport
CX034_RS07390	COG0765	amino acid transport
CX034_RS07395	COG1126	abc transporter atp-binding protein
CX034_RS07450	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CX034_RS07460	COG2944	sequence-specific DNA binding
CX034_RS07470	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CX034_RS07475	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CX034_RS07480	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CX034_RS07485	COG0009	L-threonylcarbamoyladenylate synthase
CX034_RS07490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CX034_RS07495	COG1414	Transcriptional regulator
CX034_RS07510	COG0765	amino acid transport
CX034_RS07515	COG1126	abc transporter atp-binding protein
CX034_RS07520	COG0028	Belongs to the TPP enzyme family
CX034_RS07535	COG0028	Belongs to the TPP enzyme family
CX034_RS07540	COG0583	DNA-binding transcription factor activity
CX034_RS07545	COG4974	Belongs to the 'phage' integrase family
CX034_RS07550	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CX034_RS07555	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CX034_RS07570	COG1686	Belongs to the peptidase S11 family
CX034_RS07580	COG2814	Major facilitator Superfamily
CX034_RS07590	COG1074	ATP-dependent DNA helicase activity
CX034_RS07600	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CX034_RS07605	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CX034_RS07610	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CX034_RS07630	COG2321	neutral zinc metallopeptidase
CX034_RS07635	COG0009	L-threonylcarbamoyladenylate synthase
CX034_RS07680	COG3360	Dodecin
CX034_RS07685	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CX034_RS07690	COG2850	peptidyl-arginine hydroxylation
CX034_RS07695	COG3539	Fimbrial protein
CX034_RS07700	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CX034_RS07705	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CX034_RS07720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CX034_RS07725	COG0765	amino acid transport
CX034_RS07730	COG1126	abc transporter atp-binding protein
CX034_RS07735	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CX034_RS07740	COG1758	RNA polymerase activity
CX034_RS07745	COG0194	GDP metabolic process
CX034_RS07750	COG3258	Cytochrome c
CX034_RS07755	COG2863	cytochrome
CX034_RS07760	COG1028	Short-chain dehydrogenase reductase Sdr
CX034_RS07765	COG0791	NLP P60 protein
CX034_RS07770	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CX034_RS07790	COG1561	YicC-like family, N-terminal region
CX034_RS07795	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CX034_RS07815	COG2199	diguanylate cyclase activity
CX034_RS07815	COG2200	EAL domain
CX034_RS07820	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CX034_RS07830	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CX034_RS07835	COG0174	glutamine synthetase
CX034_RS07845	COG2204	response regulator
CX034_RS07850	COG0583	DNA-binding transcription factor activity
CX034_RS07855	COG1741	Belongs to the pirin family
CX034_RS07860	COG1741	Belongs to the pirin family
CX034_RS07870	COG3842	ATPase activity
CX034_RS07875	COG1178	ABC-type Fe3 transport system permease component
CX034_RS07880	COG1840	ABC-type Fe3 transport system, periplasmic component
CX034_RS07890	COG0583	DNA-binding transcription factor activity
CX034_RS07900	COG0656	L-ascorbic acid biosynthetic process
CX034_RS07915	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CX034_RS07920	COG0583	DNA-binding transcription factor activity
CX034_RS07935	COG0783	Belongs to the Dps family
CX034_RS07955	COG0463	Glycosyl transferase, family 2
CX034_RS07975	COG0438	transferase activity, transferring glycosyl groups
CX034_RS07990	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CX034_RS08015	COG0300	oxidoreductase activity
CX034_RS08060	COG0861	Integral membrane protein TerC family
CX034_RS08065	COG1028	Short-chain dehydrogenase reductase Sdr
CX034_RS08085	COG0714	Associated with various cellular activities
CX034_RS08120	COG3119	arylsulfatase activity
CX034_RS08145	COG2197	response regulator
CX034_RS08155	COG2944	sequence-specific DNA binding
CX034_RS08165	COG0625	glutathione transferase activity
CX034_RS08195	COG0179	Fumarylacetoacetate (FAA) hydrolase
CX034_RS08200	COG1028	Short-chain dehydrogenase reductase Sdr
CX034_RS08245	COG0431	NADPH-dependent FMN reductase
CX034_RS08275	COG1028	Short-chain dehydrogenase reductase Sdr
CX034_RS08280	COG0583	DNA-binding transcription factor activity
CX034_RS08300	COG2111	Na H antiporter
CX034_RS08300	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CX034_RS08305	COG1006	Multisubunit Na H antiporter MnhC subunit
CX034_RS08310	COG0651	ATP synthesis coupled electron transport
CX034_RS08315	COG1863	multisubunit Na H antiporter MnhE subunit
CX034_RS08320	COG2212	antiporter activity
CX034_RS08345	COG0590	tRNA wobble adenosine to inosine editing
CX034_RS08350	COG1619	proteins homologs of microcin C7 resistance protein MccF
CX034_RS08355	COG1024	Enoyl-CoA hydratase
CX034_RS08370	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CX034_RS08375	COG0488	(ABC) transporter
CX034_RS08410	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CX034_RS08410	COG1017	nitric oxide dioxygenase activity
CX034_RS08415	COG1959	2 iron, 2 sulfur cluster binding
CX034_RS08420	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CX034_RS08440	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CX034_RS08445	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CX034_RS08450	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CX034_RS08455	COG0084	hydrolase, TatD family'
CX034_RS08470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CX034_RS08480	COG1126	abc transporter atp-binding protein
CX034_RS08490	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CX034_RS08505	COG0028	Belongs to the TPP enzyme family
CX034_RS08515	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CX034_RS08515	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CX034_RS08525	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CX034_RS08575	COG4336	lyase activity
CX034_RS08585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CX034_RS08585	COG2205	protein histidine kinase activity
CX034_RS08590	COG2197	response regulator
CX034_RS08610	COG3121	Chaperone
CX034_RS08615	COG3188	usher protein
CX034_RS08620	COG3539	Fimbrial protein
CX034_RS08625	COG2831	hemolysin activation secretion protein
CX034_RS08640	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CX034_RS08690	COG0668	transmembrane transport
CX034_RS08710	COG0483	inositol monophosphate 1-phosphatase activity
CX034_RS08715	COG1253	flavin adenine dinucleotide binding
CX034_RS08720	COG1968	undecaprenyl-diphosphatase activity
CX034_RS08725	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CX034_RS08740	COG0215	cysteine-tRNA ligase activity
CX034_RS08750	COG0825	malonyl-CoA metabolic process
CX034_RS08760	COG0037	tRNA processing
CX034_RS08765	COG0527	aspartate kinase activity
CX034_RS08790	COG1250	3-hydroxyacyl-CoA dehydrogenase
CX034_RS08795	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CX034_RS08795	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CX034_RS08810	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CX034_RS08815	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
CX034_RS08820	COG1028	Short-chain dehydrogenase reductase Sdr
CX034_RS08830	COG0583	DNA-binding transcription factor activity
CX034_RS08855	COG3842	ATPase activity
CX034_RS08865	COG0446	pyridine nucleotide-disulphide oxidoreductase
CX034_RS08865	COG1902	pentaerythritol trinitrate reductase activity
CX034_RS08870	COG1414	Transcriptional regulator
CX034_RS08875	COG1832	CoA-binding protein
CX034_RS08885	COG0251	oxidation-reduction process
CX034_RS08910	COG1902	pentaerythritol trinitrate reductase activity
CX034_RS08920	COG1215	transferase activity, transferring glycosyl groups
CX034_RS08925	COG1649	PFAM Uncharacterised BCR, COG1649
CX034_RS08925	COG0726	polysaccharide deacetylase
CX034_RS08945	COG1846	Transcriptional regulator
CX034_RS08950	COG2197	response regulator
CX034_RS08965	COG0166	Belongs to the GPI family
CX034_RS08970	COG1045	serine acetyltransferase
CX034_RS08980	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CX034_RS08985	COG0483	inositol monophosphate 1-phosphatase activity
CX034_RS08990	COG1012	belongs to the aldehyde dehydrogenase family
CX034_RS08995	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CX034_RS09010	COG0210	DNA helicase
CX034_RS09015	COG0598	Magnesium transport protein CorA
CX034_RS09025	COG0747	negative chemotaxis
CX034_RS09030	COG0601	transmembrane transport
CX034_RS09035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CX034_RS09040	COG4172	Belongs to the ABC transporter superfamily
CX034_RS09045	COG1846	Transcriptional regulator
CX034_RS09100	COG4964	Belongs to the GSP D family
CX034_RS09140	COG2204	response regulator
CX034_RS09155	COG1595	DNA-templated transcription, initiation
CX034_RS09165	COG3474	cytochrome
CX034_RS09170	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CX034_RS09185	COG3384	dioxygenase
CX034_RS09190	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CX034_RS09220	COG2885	chlorophyll binding
CX034_RS09255	COG0697	spore germination
CX034_RS09260	COG0730	response to heat
CX034_RS09280	COG0583	DNA-binding transcription factor activity
CX034_RS09285	COG0427	acetyl-CoA hydrolase
CX034_RS09340	COG1250	3-hydroxyacyl-CoA dehydrogenase
CX034_RS09345	COG0154	amidase activity
CX034_RS09355	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CX034_RS09370	COG0495	leucyl-tRNA aminoacylation
CX034_RS09375	COG2814	Major facilitator Superfamily
CX034_RS09410	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CX034_RS09415	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CX034_RS09420	COG2814	Major facilitator Superfamily
CX034_RS09440	COG4176	ABC-type proline glycine betaine transport system permease component
CX034_RS09450	COG1942	4-Oxalocrotonate Tautomerase
CX034_RS09455	COG0183	Belongs to the thiolase family
CX034_RS09465	COG1802	Transcriptional regulator
CX034_RS09475	COG1024	Enoyl-CoA hydratase
CX034_RS09490	COG2032	superoxide dismutase activity
CX034_RS09505	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CX034_RS09530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CX034_RS09535	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CX034_RS09545	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CX034_RS09550	COG0736	holo-[acyl-carrier-protein] synthase activity
CX034_RS09555	COG1472	Belongs to the glycosyl hydrolase 3 family
CX034_RS09560	COG0322	excinuclease ABC activity
CX034_RS09565	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CX034_RS09575	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CX034_RS09575	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CX034_RS09580	COG2224	Isocitrate lyase
CX034_RS09605	COG0559	Belongs to the binding-protein-dependent transport system permease family
CX034_RS09615	COG4638	Rieske (2fe-2S)
CX034_RS09625	COG1024	Enoyl-CoA hydratase
CX034_RS09635	COG0633	Ferredoxin
CX034_RS09640	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX034_RS09655	COG0183	Belongs to the thiolase family
CX034_RS09670	COG0583	DNA-binding transcription factor activity
CX034_RS09710	COG2346	COG2346, Truncated hemoglobins
CX034_RS09840	COG2207	Transcriptional regulator
CX034_RS09890	COG1132	(ABC) transporter
CX034_RS09915	COG0659	secondary active sulfate transmembrane transporter activity
CX034_RS09945	COG2169	Transcriptional regulator
CX034_RS09950	COG5507	3-demethylubiquinone-9 3-methyltransferase
CX034_RS09955	COG0384	phenazine biosynthesis protein PhzF
CX034_RS09960	COG0583	DNA-binding transcription factor activity
CX034_RS09965	COG2733	membrane
CX034_RS09980	COG1012	belongs to the aldehyde dehydrogenase family
CX034_RS09985	COG3284	Transcriptional regulator
CX034_RS10010	COG1380	Effector of murein hydrolase LrgA
CX034_RS10015	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CX034_RS10015	COG4106	trans-aconitate 2-methyltransferase activity
CX034_RS10025	COG0156	8-amino-7-oxononanoate synthase activity
CX034_RS10095	COG1131	(ABC) transporter
CX034_RS10100	COG0842	Transport permease protein
CX034_RS10105	COG0628	permease
CX034_RS10140	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CX034_RS10150	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CX034_RS10155	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CX034_RS10160	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CX034_RS10165	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CX034_RS10170	COG0330	HflC and HflK could
CX034_RS10175	COG0330	HflC and HflK could
CX034_RS10180	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CX034_RS10185	COG1923	regulation of RNA biosynthetic process
CX034_RS10190	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CX034_RS10195	COG1160	GTP binding
CX034_RS10200	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CX034_RS10205	COG2976	Protein conserved in bacteria
CX034_RS10210	COG0124	histidyl-tRNA synthetase
CX034_RS10215	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CX034_RS10225	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CX034_RS10230	COG0105	UTP biosynthetic process
CX034_RS10235	COG0525	valine-tRNA ligase activity
CX034_RS10250	COG0642	Histidine kinase
CX034_RS10275	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CX034_RS10280	COG0336	Belongs to the RNA methyltransferase TrmD family
CX034_RS10285	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CX034_RS10290	COG0228	four-way junction DNA binding
CX034_RS10300	COG0425	Belongs to the sulfur carrier protein TusA family
CX034_RS10305	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CX034_RS10350	COG0154	amidase activity
CX034_RS10355	COG4172	Belongs to the ABC transporter superfamily
CX034_RS10360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CX034_RS10365	COG0601	transmembrane transport
CX034_RS10370	COG0747	negative chemotaxis
CX034_RS10400	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CX034_RS10410	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CX034_RS10430	COG3395	kinase activity
CX034_RS10445	COG1024	Enoyl-CoA hydratase
CX034_RS10465	COG0633	Ferredoxin
CX034_RS10470	COG0443	Heat shock 70 kDa protein
CX034_RS10475	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CX034_RS10480	COG0316	Belongs to the HesB IscA family
CX034_RS10485	COG0822	iron-sulfur transferase activity
CX034_RS10490	COG1104	cysteine desulfurase activity
CX034_RS10500	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CX034_RS10505	COG0556	nucleotide-excision repair
CX034_RS10515	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CX034_RS10545	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CX034_RS10565	COG1028	Short-chain dehydrogenase reductase Sdr
CX034_RS10570	COG0183	Belongs to the thiolase family
CX034_RS10580	COG1024	Enoyl-CoA hydratase
CX034_RS10595	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX034_RS10600	COG0583	DNA-binding transcription factor activity
CX034_RS10605	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CX034_RS10610	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CX034_RS10615	COG0740	serine-type endopeptidase activity
CX034_RS10620	COG0544	peptidyl-prolyl cis-trans isomerase activity
CX034_RS10630	COG1278	Cold shock
CX034_RS10640	COG1278	Cold shock
CX034_RS10675	COG2171	N-acyltransferase activity
CX034_RS10680	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CX034_RS10685	COG2890	protein-(glutamine-N5) methyltransferase activity
CX034_RS10690	COG0488	(ABC) transporter
CX034_RS10695	COG4771	TonB-dependent receptor
CX034_RS10700	COG0210	DNA helicase
CX034_RS10720	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CX034_RS10725	COG0196	riboflavin kinase activity
CX034_RS10730	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CX034_RS10735	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CX034_RS10740	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CX034_RS10750	COG1522	sequence-specific DNA binding
CX034_RS10770	COG2951	lytic endotransglycosylase activity
CX034_RS10775	COG2833	Protein of unknown function (DUF455)
CX034_RS10795	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CX034_RS10795	COG0189	ligase activity
CX034_RS10800	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CX034_RS10800	COG1181	Belongs to the D-alanine--D-alanine ligase family
CX034_RS10805	COG3237	CsbD-like
CX034_RS10815	COG2823	Periplasmic or secreted lipoprotein
CX034_RS10840	COG4181	ATPase activity
CX034_RS10850	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CX034_RS10855	COG0584	glycerophosphoryl diester phosphodiesterase
CX034_RS10860	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CX034_RS10870	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CX034_RS10870	COG0678	peroxiredoxin activity
CX034_RS10880	COG0789	Transcriptional regulator
CX034_RS10885	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CX034_RS10915	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CX034_RS10920	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CX034_RS10930	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CX034_RS10935	COG2252	PERMEase
CX034_RS10945	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CX034_RS10975	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CX034_RS10980	COG2358	TRAP transporter, solute receptor (TAXI family
CX034_RS11015	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CX034_RS11020	COG1366	Belongs to the anti-sigma-factor antagonist family
CX034_RS11025	COG2172	sigma factor antagonist activity
CX034_RS11030	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CX034_RS11040	COG2770	Histidine kinase
CX034_RS11040	COG2208	phosphoserine phosphatase activity
CX034_RS11065	COG1595	DNA-templated transcription, initiation
CX034_RS11080	COG4792	protein secretion
CX034_RS11085	COG4791	protein targeting
CX034_RS11090	COG4794	Type iii secretion
CX034_RS11095	COG4790	Type iii secretion
CX034_RS11130	COG4669	(LipO)protein
CX034_RS11195	COG4789	Type iii secretion
CX034_RS11225	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CX034_RS11230	COG0840	transmembrane signaling receptor activity
CX034_RS11235	COG2233	PERMEase
CX034_RS11260	COG1840	ABC-type Fe3 transport system, periplasmic component
CX034_RS11265	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CX034_RS11270	COG1178	ABC-type Fe3 transport system permease component
CX034_RS11275	COG3842	ATPase activity
CX034_RS11280	COG0583	DNA-binding transcription factor activity
CX034_RS11300	COG0501	Belongs to the peptidase M48B family
CX034_RS11310	COG0697	spore germination
CX034_RS11320	COG1846	Transcriptional regulator
CX034_RS11330	COG1566	PFAM secretion protein HlyD family protein
CX034_RS11335	COG2814	Major facilitator Superfamily
CX034_RS11340	COG0473	3-isopropylmalate dehydrogenase activity
CX034_RS11350	COG0747	negative chemotaxis
CX034_RS11360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CX034_RS11375	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CX034_RS11400	COG1012	belongs to the aldehyde dehydrogenase family
CX034_RS11410	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CX034_RS11415	COG1115	amino acid carrier protein
CX034_RS11420	COG0433	COG0433 Predicted ATPase
CX034_RS11425	COG0217	transcriptional regulatory protein
CX034_RS11430	COG0151	Belongs to the GarS family
CX034_RS11435	COG0408	coproporphyrinogen oxidase activity
CX034_RS11440	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CX034_RS11445	COG0799	negative regulation of ribosome biogenesis
CX034_RS11450	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CX034_RS11455	COG0424	maF-like protein
CX034_RS11460	COG3468	outer membrane autotransporter barrel domain protein
CX034_RS11500	COG1530	ribonuclease E activity
CX034_RS11505	COG0077	Prephenate dehydratase
CX034_RS11520	COG1132	(ABC) transporter
CX034_RS11525	COG0859	PFAM glycosyl transferase family 9
CX034_RS11550	COG2194	sulfuric ester hydrolase activity
CX034_RS11555	COG0438	transferase activity, transferring glycosyl groups
CX034_RS11560	COG0463	Glycosyl transferase, family 2
CX034_RS11565	COG0726	polysaccharide deacetylase
CX034_RS11570	COG0438	transferase activity, transferring glycosyl groups
CX034_RS11585	COG1643	Atp-dependent helicase
CX034_RS11590	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CX034_RS11590	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CX034_RS11595	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CX034_RS11605	COG0704	Plays a role in the regulation of phosphate uptake
CX034_RS11610	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CX034_RS11615	COG1960	acyl-CoA dehydrogenase activity
CX034_RS11640	COG1177	transmembrane transport
CX034_RS11645	COG1176	ABC-type spermidine putrescine transport system, permease component I
CX034_RS11650	COG3842	ATPase activity
CX034_RS11655	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CX034_RS11670	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CX034_RS11675	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CX034_RS11685	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CX034_RS11685	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CX034_RS11700	COG0372	Belongs to the citrate synthase family
CX034_RS11705	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CX034_RS11710	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CX034_RS11715	COG1053	succinate dehydrogenase
CX034_RS11720	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CX034_RS11725	COG2009	succinate dehydrogenase
CX034_RS11730	COG2188	Transcriptional regulator
CX034_RS11735	COG0039	L-malate dehydrogenase activity
CX034_RS11765	COG1981	membrane
CX034_RS11790	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CX034_RS11800	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CX034_RS11830	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CX034_RS11835	COG0148	phosphopyruvate hydratase activity
CX034_RS11845	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CX034_RS11850	COG0504	CTP synthase activity
CX034_RS11875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CX034_RS11885	COG0747	negative chemotaxis
CX034_RS11890	COG4172	Belongs to the ABC transporter superfamily
CX034_RS11895	COG1446	asparaginase
CX034_RS11925	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CX034_RS11940	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CX034_RS11945	COG0697	spore germination
CX034_RS11950	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CX034_RS11960	COG3193	protein, possibly involved in utilization of glycolate and propanediol
CX034_RS11970	COG0791	NLP P60 protein
CX034_RS11985	COG0583	DNA-binding transcription factor activity
CX034_RS12000	COG0583	DNA-binding transcription factor activity
CX034_RS12010	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CX034_RS12025	COG0670	Belongs to the BI1 family
CX034_RS12030	COG3181	Tripartite tricarboxylate transporter family receptor
CX034_RS12045	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CX034_RS12055	COG1381	Involved in DNA repair and RecF pathway recombination
CX034_RS12060	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CX034_RS12065	COG0571	ribonuclease III activity
CX034_RS12070	COG0681	Belongs to the peptidase S26 family
CX034_RS12075	COG0481	GTPase activity
CX034_RS12080	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CX034_RS12105	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CX034_RS12110	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CX034_RS12125	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CX034_RS12130	COG0416	fatty acid biosynthetic process
CX034_RS12135	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CX034_RS12140	COG1399	metal-binding, possibly nucleic acid-binding protein
CX034_RS12145	COG0424	maF-like protein
CX034_RS12155	COG3023	N-Acetylmuramoyl-L-alanine amidase
CX034_RS12170	COG3022	response to hydroperoxide
CX034_RS12185	COG0135	phosphoribosylanthranilate isomerase activity
CX034_RS12200	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CX034_RS12205	COG0101	tRNA pseudouridine synthase activity
CX034_RS12215	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CX034_RS12220	COG0473	3-isopropylmalate dehydrogenase activity
CX034_RS12225	COG0066	3-isopropylmalate dehydratase activity
CX034_RS12230	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CX034_RS12240	COG1122	ATPase activity
CX034_RS12275	COG3383	formate dehydrogenase (NAD+) activity
CX034_RS12275	COG0243	molybdopterin cofactor binding
CX034_RS12305	COG0489	protein tyrosine kinase activity
CX034_RS12310	COG0746	molybdenum cofactor guanylyltransferase activity
CX034_RS12315	COG0303	'Molybdopterin
CX034_RS12320	COG1763	Mo-molybdopterin cofactor biosynthetic process
CX034_RS12330	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CX034_RS12335	COG5001	Diguanylate cyclase
CX034_RS12355	COG3842	ATPase activity
CX034_RS12365	COG0406	alpha-ribazole phosphatase activity
CX034_RS12375	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CX034_RS12380	COG0505	Belongs to the CarA family
CX034_RS12385	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CX034_RS12420	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CX034_RS12425	COG1960	acyl-CoA dehydrogenase activity
CX034_RS12435	COG2867	negative regulation of translational initiation
CX034_RS12445	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CX034_RS12450	COG3706	GGDEF domain
CX034_RS12455	COG0330	HflC and HflK could
CX034_RS12470	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CX034_RS12470	COG0519	Catalyzes the synthesis of GMP from XMP
CX034_RS12480	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CX034_RS12485	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CX034_RS12490	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CX034_RS12495	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CX034_RS12505	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CX034_RS12510	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CX034_RS12515	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CX034_RS12520	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CX034_RS12525	COG0750	zinc metalloprotease
CX034_RS12530	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CX034_RS12540	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CX034_RS12545	COG0233	cytoplasmic translational termination
CX034_RS12550	COG0528	UMP kinase activity
CX034_RS12555	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CX034_RS12560	COG0052	Belongs to the universal ribosomal protein uS2 family
CX034_RS12565	COG0024	Methionine aminopeptidase
CX034_RS12570	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CX034_RS12600	COG0285	dihydrofolate synthase activity
CX034_RS12635	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CX034_RS12645	COG1677	Flagellar hook-basal body complex protein FliE
CX034_RS12655	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CX034_RS12665	COG1157	protein secretion by the type III secretion system
CX034_RS12690	COG1580	Controls the rotational direction of flagella during chemotaxis
CX034_RS12710	COG1338	Plays a role in the flagellum-specific transport system
CX034_RS12730	COG0840	transmembrane signaling receptor activity
CX034_RS12735	COG0840	transmembrane signaling receptor activity
CX034_RS12740	COG0840	transmembrane signaling receptor activity
CX034_RS12750	COG1256	bacterial-type flagellum assembly
CX034_RS12760	COG1706	bacterial-type flagellum-dependent cell motility
CX034_RS12765	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CX034_RS12780	COG1749	Flagellar hook protein flgE
CX034_RS12790	COG1558	bacterial-type flagellum-dependent cell motility
CX034_RS12795	COG1815	bacterial-type flagellum-dependent cell motility
CX034_RS12835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CX034_RS12840	COG0765	amino acid transport
CX034_RS12845	COG1126	abc transporter atp-binding protein
CX034_RS12860	COG4948	Mandelate Racemase Muconate Lactonizing
CX034_RS12865	COG3181	Tripartite tricarboxylate transporter family receptor
CX034_RS12875	COG0066	3-isopropylmalate dehydratase activity
CX034_RS12890	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX034_RS12900	COG3181	Tripartite tricarboxylate transporter family receptor
CX034_RS12910	COG1802	Transcriptional regulator
CX034_RS12925	COG0583	DNA-binding transcription factor activity
CX034_RS12945	COG1695	Transcriptional regulator
CX034_RS12955	COG3568	Endonuclease Exonuclease Phosphatase
CX034_RS12960	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CX034_RS13010	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CX034_RS13020	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CX034_RS13040	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CX034_RS13070	COG0667	Aldo Keto reductase
CX034_RS13085	COG2259	Doxx family
CX034_RS13115	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX034_RS13135	COG0386	Belongs to the glutathione peroxidase family
CX034_RS13140	COG0625	glutathione transferase activity
CX034_RS13155	COG0095	Lipoate-protein ligase
CX034_RS13170	COG0688	phosphatidylethanolamine metabolic process
CX034_RS13180	COG1464	Belongs to the NlpA lipoprotein family
CX034_RS13195	COG2363	Small membrane protein
CX034_RS13220	COG3842	ATPase activity
CX034_RS13225	COG0395	ABC-type sugar transport system, permease component
CX034_RS13230	COG1175	transmembrane transport
CX034_RS13235	COG1653	transport
CX034_RS13245	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CX034_RS13265	COG0559	Belongs to the binding-protein-dependent transport system permease family
CX034_RS13285	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CX034_RS13310	COG2311	Membrane
CX034_RS13335	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CX034_RS13345	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CX034_RS13350	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CX034_RS13355	COG1760	l-serine dehydratase
CX034_RS13360	COG1283	sodium-dependent phosphate transmembrane transporter activity
CX034_RS13365	COG0412	Dienelactone hydrolase
CX034_RS13380	COG1611	Belongs to the LOG family
CX034_RS13400	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CX034_RS13405	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CX034_RS13410	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CX034_RS13415	COG2251	uridine kinase activity
CX034_RS13415	COG0195	Participates in both transcription termination and antitermination
CX034_RS13420	COG0779	Required for maturation of 30S ribosomal subunits
CX034_RS13425	COG1187	pseudouridine synthase activity
CX034_RS13430	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CX034_RS13440	COG0583	DNA-binding transcription factor activity
CX034_RS13450	COG0523	cobalamin synthesis protein
CX034_RS13470	COG0625	glutathione transferase activity
CX034_RS13475	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CX034_RS13480	COG1047	Peptidyl-prolyl cis-trans
CX034_RS13485	COG2003	Belongs to the UPF0758 family
CX034_RS13490	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CX034_RS13495	COG3483	tryptophan 2,3-dioxygenase activity
CX034_RS13500	COG0254	rRNA binding
CX034_RS13510	COG0534	Mate efflux family protein
CX034_RS13530	COG2304	oxidoreductase activity
CX034_RS13550	COG1028	Short-chain dehydrogenase reductase Sdr
CX034_RS13555	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CX034_RS13560	COG1562	ergosterol biosynthetic process
CX034_RS13565	COG1562	ergosterol biosynthetic process
CX034_RS13570	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CX034_RS13570	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CX034_RS13575	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CX034_RS13585	COG0842	Transport permease protein
CX034_RS13590	COG1131	(ABC) transporter
CX034_RS13610	COG1477	protein flavinylation
CX034_RS13625	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CX034_RS13640	COG5564	TIM-barrel signal transduction protein
CX034_RS13645	COG5441	Belongs to the UPF0261 family
CX034_RS13655	COG3468	outer membrane autotransporter barrel domain protein
CX034_RS13675	COG0542	response to heat
CX034_RS13680	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CX034_RS13695	COG0494	nUDIX hydrolase
CX034_RS13700	COG3530	Putative quorum-sensing-regulated virulence factor
CX034_RS13710	COG1595	DNA-templated transcription, initiation
CX034_RS13715	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CX034_RS13750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CX034_RS13755	COG0765	amino acid transport
CX034_RS13760	COG0765	amino acid transport
CX034_RS13795	COG2988	succinylglutamate desuccinylase activity
CX034_RS13820	COG3181	Tripartite tricarboxylate transporter family receptor
CX034_RS13825	COG2084	Dehydrogenase
CX034_RS13840	COG1619	proteins homologs of microcin C7 resistance protein MccF
CX034_RS13855	COG2814	Major facilitator Superfamily
CX034_RS13865	COG0583	DNA-binding transcription factor activity
CX034_RS13905	COG0672	)-iron permease
CX034_RS13920	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
CX034_RS13925	COG1028	Short-chain dehydrogenase reductase Sdr
CX034_RS13930	COG3243	poly(R)-hydroxyalkanoic acid synthase
CX034_RS13940	COG0564	pseudouridine synthase activity
CX034_RS13950	COG1199	ATP-dependent helicase activity
CX034_RS13955	COG2183	response to ionizing radiation
CX034_RS13960	COG0180	Tryptophanyl-tRNA synthetase
CX034_RS13985	COG3181	Tripartite tricarboxylate transporter family receptor
CX034_RS13995	COG0583	DNA-binding transcription factor activity
CX034_RS14000	COG1028	Short-chain dehydrogenase reductase Sdr
CX034_RS14005	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CX034_RS14010	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CX034_RS14015	COG0508	dehydrogenase complex catalyzes the overall conversion of
CX034_RS14020	COG0567	Dehydrogenase, E1 component
CX034_RS14030	COG1522	sequence-specific DNA binding
CX034_RS14040	COG0280	phosphate acetyltransferase
CX034_RS14040	COG0281	malic enzyme
CX034_RS14045	COG3539	Fimbrial protein
CX034_RS14065	COG0613	PHP domain protein
CX034_RS14075	COG2333	competence protein COMEC
CX034_RS14075	COG0658	competence protein
CX034_RS14100	COG0084	hydrolase, TatD family'
CX034_RS14105	COG1136	(ABC) transporter
CX034_RS14120	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CX034_RS14130	COG1028	Short-chain dehydrogenase reductase Sdr
CX034_RS14135	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CX034_RS14150	COG1022	Amp-dependent synthetase and ligase
CX034_RS14185	COG2205	protein histidine kinase activity
CX034_RS14190	COG0745	RESPONSE REGULATOR receiver
CX034_RS14195	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CX034_RS14205	COG1295	ribonuclease BN
CX034_RS14220	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CX034_RS14250	COG1534	Rna-binding protein
CX034_RS14255	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CX034_RS14260	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CX034_RS14270	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CX034_RS14280	COG0248	Ppx GppA phosphatase
CX034_RS14305	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CX034_RS14320	COG2732	(Barnase) inhibitor
CX034_RS14330	COG0281	malic enzyme
CX034_RS14330	COG0280	phosphate acetyltransferase
CX034_RS14340	COG0436	Aminotransferase
CX034_RS14350	COG0741	lytic transglycosylase activity
CX034_RS14355	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CX034_RS14380	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CX034_RS14380	COG1648	precorrin-2 dehydrogenase activity
CX034_RS14385	COG3468	outer membrane autotransporter barrel domain protein
CX034_RS14395	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CX034_RS14400	COG2027	D-alanyl-D-alanine carboxypeptidase
CX034_RS14405	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CX034_RS14410	COG0343	queuine tRNA-ribosyltransferase activity
CX034_RS14415	COG1862	Preprotein translocase
CX034_RS14420	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CX034_RS14425	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CX034_RS14440	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CX034_RS14445	COG1702	phosphate starvation-inducible protein PhoH
CX034_RS14450	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CX034_RS14455	COG4535	Mg2 and Co2 transporter CorC
CX034_RS14465	COG0667	Aldo Keto reductase
CX034_RS14490	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CX034_RS14495	COG0745	RESPONSE REGULATOR receiver
CX034_RS14500	COG2201	protein-glutamate methylesterase activity
CX034_RS14510	COG0840	transmembrane signaling receptor activity
CX034_RS14525	COG0745	RESPONSE REGULATOR receiver
CX034_RS14560	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CX034_RS14570	COG0739	heme binding
CX034_RS14580	COG0521	Mo-molybdopterin cofactor biosynthetic process
CX034_RS14590	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CX034_RS14620	COG0625	glutathione transferase activity
CX034_RS14635	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CX034_RS14640	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CX034_RS14645	COG0126	phosphoglycerate kinase activity
CX034_RS14650	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CX034_RS14655	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CX034_RS14660	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CX034_RS14670	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CX034_RS14675	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CX034_RS14680	COG0508	dehydrogenase complex catalyzes the overall conversion of
CX034_RS14685	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CX034_RS14695	COG4566	intracellular signal transduction
CX034_RS14700	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CX034_RS14705	COG0339	signal peptide processing
CX034_RS14710	COG1999	signal sequence binding
CX034_RS14740	COG1187	pseudouridine synthase activity
CX034_RS14745	COG3161	chorismate lyase activity
CX034_RS14760	COG0667	Aldo Keto reductase
CX034_RS14775	COG0335	large ribosomal subunit rRNA binding
CX034_RS14810	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CX034_RS14830	COG0450	alkyl hydroperoxide reductase
CX034_RS14835	COG1960	acyl-CoA dehydrogenase activity
CX034_RS14850	COG0123	including yeast histone deacetylase and acetoin utilization protein
CX034_RS14855	COG2951	lytic endotransglycosylase activity
CX034_RS14870	COG1596	polysaccharide export
CX034_RS14870	COG1555	photosystem II stabilization
CX034_RS14875	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CX034_RS14880	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CX034_RS14885	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CX034_RS14905	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CX034_RS14910	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CX034_RS14915	COG0287	Prephenate dehydrogenase
CX034_RS14925	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CX034_RS14940	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CX034_RS14950	COG2814	Major facilitator Superfamily
CX034_RS14980	COG0583	DNA-binding transcription factor activity
CX034_RS15020	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CX034_RS15035	COG0667	Aldo Keto reductase
CX034_RS15045	COG5265	(ABC) transporter
CX034_RS15095	COG0439	Biotin carboxylase
CX034_RS15100	COG2188	Transcriptional regulator
CX034_RS15125	COG0511	ligase activity, forming carbon-carbon bonds
CX034_RS15135	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CX034_RS15155	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CX034_RS15175	COG0500	methyltransferase
CX034_RS15180	COG5265	(ABC) transporter
CX034_RS15195	COG0028	Belongs to the TPP enzyme family
CX034_RS15200	COG0440	acetolactate synthase activity
CX034_RS15205	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CX034_RS15210	COG1183	phosphatidylcholine synthase activity
CX034_RS15225	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CX034_RS15230	COG1185	polyribonucleotide nucleotidyltransferase activity
CX034_RS15245	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CX034_RS15265	COG0149	triose-phosphate isomerase activity
CX034_RS15270	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CX034_RS15280	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CX034_RS15290	COG3799	methylaspartate ammonia-lyase activity
CX034_RS15325	COG0583	DNA-binding transcription factor activity
CX034_RS15330	COG0626	cystathionine gamma-synthase activity
CX034_RS15335	COG3608	succinylglutamate desuccinylase aspartoacylase
CX034_RS15355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CX034_RS15375	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
CX034_RS15390	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CX034_RS15395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CX034_RS15400	COG1733	regulation of RNA biosynthetic process
CX034_RS15410	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CX034_RS15415	COG0583	DNA-binding transcription factor activity
CX034_RS15420	COG1597	lipid kinase activity
CX034_RS15430	COG0671	phosphoesterase, PA-phosphatase related
CX034_RS15460	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CX034_RS15465	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CX034_RS15470	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CX034_RS15475	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CX034_RS15480	COG0649	NAD binding
CX034_RS15485	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CX034_RS15495	COG1034	ATP synthesis coupled electron transport
CX034_RS15500	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CX034_RS15505	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CX034_RS15515	COG0713	ATP synthesis coupled electron transport
CX034_RS15530	COG1007	ATP synthesis coupled electron transport
CX034_RS15540	COG4774	siderophore transport
CX034_RS15545	COG4774	siderophore transport
CX034_RS15560	COG0028	Belongs to the TPP enzyme family
CX034_RS15565	COG3181	Tripartite tricarboxylate transporter family receptor
CX034_RS15570	COG0583	DNA-binding transcription factor activity
CX034_RS15575	COG0560	Phosphoserine phosphatase
CX034_RS15580	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CX034_RS15585	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CX034_RS15590	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CX034_RS15605	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CX034_RS15610	COG0308	aminopeptidase N
CX034_RS15630	COG0028	Belongs to the TPP enzyme family
CX034_RS15650	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CX034_RS15660	COG0318	PFAM AMP-dependent synthetase and ligase
CX034_RS15670	COG1802	Transcriptional regulator
CX034_RS15680	COG1802	Transcriptional regulator
CX034_RS15690	COG1028	Short-chain dehydrogenase reductase Sdr
CX034_RS15710	COG1126	abc transporter atp-binding protein
CX034_RS15715	COG0765	amino acid transport
CX034_RS15735	COG1538	Outer membrane efflux protein
CX034_RS15740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CX034_RS15745	COG2274	protein secretion by the type I secretion system
CX034_RS15750	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CX034_RS15760	COG2994	toxin metabolic process
CX034_RS15780	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CX034_RS15785	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
CX034_RS15795	COG0583	DNA-binding transcription factor activity
CX034_RS15805	COG0142	geranyltranstransferase activity
CX034_RS15815	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CX034_RS15820	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CX034_RS15825	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CX034_RS15830	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CX034_RS15875	COG3712	iron ion homeostasis
CX034_RS15880	COG4774	siderophore transport
CX034_RS15885	COG2353	YceI-like domain
CX034_RS15900	COG0019	diaminopimelate decarboxylase activity
CX034_RS15920	COG0747	negative chemotaxis
CX034_RS15925	COG0601	transmembrane transport
CX034_RS15930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CX034_RS15940	COG0154	amidase activity
CX034_RS15945	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CX034_RS15970	COG2154	pterin-4-alpha-carbinolamine dehydratase
CX034_RS15980	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CX034_RS15990	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CX034_RS15995	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CX034_RS16000	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CX034_RS16005	COG1929	Belongs to the glycerate kinase type-1 family
CX034_RS16010	COG0469	pyruvate kinase activity
CX034_RS16015	COG0700	Nucleoside recognition
CX034_RS16050	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CX034_RS16055	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CX034_RS16070	COG0823	Involved in the tonB-independent uptake of proteins
CX034_RS16080	COG0848	biopolymer transport protein
CX034_RS16085	COG0811	peptide transport
CX034_RS16090	COG0824	Thioesterase
CX034_RS16095	COG0442	prolyl-tRNA aminoacylation
CX034_RS16100	COG0494	nUDIX hydrolase
CX034_RS16115	COG2135	peptidase activity
CX034_RS16190	COG1196	nuclear chromosome segregation
CX034_RS16330	COG1464	Belongs to the NlpA lipoprotein family
CX034_RS16360	COG4211	Belongs to the binding-protein-dependent transport system permease family
CX034_RS16370	COG0154	amidase activity
CX034_RS16375	COG0288	reversible hydration of carbon dioxide
CX034_RS16390	COG0514	ATP-dependent DNA helicase (RecQ)
CX034_RS16395	COG2255	four-way junction helicase activity
CX034_RS16410	COG0632	four-way junction helicase activity
CX034_RS16415	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CX034_RS16435	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CX034_RS16445	COG0006	proline dipeptidase activity
CX034_RS16470	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CX034_RS16485	COG4783	chaperone-mediated protein folding
CX034_RS16490	COG0429	hydrolase of the alpha beta-hydrolase fold
CX034_RS16520	COG0513	Belongs to the DEAD box helicase family
CX034_RS16540	COG1546	Belongs to the CinA family
CX034_RS16540	COG1058	Belongs to the CinA family
CX034_RS16545	COG1414	Transcriptional regulator
CX034_RS16565	COG0167	dihydroorotate dehydrogenase activity
CX034_RS16570	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CX034_RS16585	COG0583	DNA-binding transcription factor activity
CX034_RS16645	COG0281	malic enzyme
CX034_RS16645	COG0280	phosphate acetyltransferase
CX034_RS16655	COG0601	transmembrane transport
CX034_RS16660	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CX034_RS16665	COG4172	Belongs to the ABC transporter superfamily
CX034_RS16695	COG0640	Transcriptional regulator
CX034_RS16710	COG3135	benzoate transporter
CX034_RS16715	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CX034_RS16720	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CX034_RS16725	COG0742	ribosomal rna small subunit methyltransferase
CX034_RS16740	COG3639	organic phosphonate transmembrane transporter activity
CX034_RS16745	COG3639	organic phosphonate transmembrane transporter activity
CX034_RS16785	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CX034_RS16790	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CX034_RS16800	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CX034_RS16805	COG1058	Belongs to the CinA family
CX034_RS16805	COG1546	Belongs to the CinA family
CX034_RS16810	COG0284	orotidine-5'-phosphate decarboxylase activity
CX034_RS16815	COG1252	NADH dehydrogenase
CX034_RS16830	COG3468	outer membrane autotransporter barrel domain protein
CX034_RS16835	COG0459	protein refolding
CX034_RS16840	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CX034_RS16860	COG1053	succinate dehydrogenase
CX034_RS16875	COG0583	DNA-binding transcription factor activity
CX034_RS16880	COG1053	succinate dehydrogenase
CX034_RS16900	COG3706	GGDEF domain
CX034_RS16940	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
CX034_RS16950	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CX034_RS16960	COG0069	glutamate synthase activity
CX034_RS16965	COG2391	methyltransferase activity
CX034_RS16970	COG0679	Auxin Efflux Carrier
CX034_RS16995	COG0557	exoribonuclease II activity
CX034_RS17000	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CX034_RS17010	COG3128	pkhd-type hydroxylase
CX034_RS17015	COG0776	regulation of translation
CX034_RS17045	COG0642	Histidine kinase
CX034_RS17050	COG3158	transport of potassium into the cell
CX034_RS17055	COG0137	argininosuccinate synthase activity
CX034_RS17060	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CX034_RS17065	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CX034_RS17075	COG0583	DNA-binding transcription factor activity
CX034_RS17085	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CX034_RS17105	COG2186	Transcriptional regulator
CX034_RS17115	COG2223	nitrite transmembrane transporter activity
CX034_RS17125	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CX034_RS17130	COG0450	alkyl hydroperoxide reductase
CX034_RS17150	COG1214	PFAM Peptidase M22, glycoprotease
CX034_RS17155	COG1573	uracil-dna glycosylase
CX034_RS17160	COG0477	Major facilitator Superfamily
CX034_RS17165	COG1196	nuclear chromosome segregation
CX034_RS17175	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CX034_RS17180	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CX034_RS17195	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CX034_RS17200	COG1122	ATPase activity
CX034_RS17205	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CX034_RS17210	COG1268	BioY protein
CX034_RS17230	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CX034_RS17265	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CX034_RS17270	COG2878	Part of a membrane complex involved in electron transport
CX034_RS17285	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CX034_RS17290	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CX034_RS17295	COG0251	oxidation-reduction process
CX034_RS17305	COG3228	Belongs to the MtfA family
CX034_RS17310	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CX034_RS17320	COG0133	tryptophan synthase activity
CX034_RS17325	COG0159	tryptophan synthase activity
CX034_RS17330	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CX034_RS17350	COG1530	ribonuclease E activity
CX034_RS17360	COG0546	phosphoglycolate phosphatase activity
CX034_RS17365	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CX034_RS17370	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CX034_RS17385	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX034_RS17390	COG0583	DNA-binding transcription factor activity
CX034_RS17400	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX034_RS17420	COG0251	oxidation-reduction process
CX034_RS17425	COG1017	nitric oxide dioxygenase activity
CX034_RS17425	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CX034_RS17430	COG2031	fatty acid transporter
CX034_RS17435	COG1012	belongs to the aldehyde dehydrogenase family
CX034_RS17440	COG1802	Transcriptional regulator
CX034_RS17450	COG1278	Cold shock
CX034_RS17455	COG0583	DNA-binding transcription factor activity
CX034_RS17480	COG0183	Belongs to the thiolase family
CX034_RS17490	COG1960	acyl-CoA dehydrogenase activity
CX034_RS17495	COG0583	DNA-binding transcription factor activity
CX034_RS17500	COG3181	Tripartite tricarboxylate transporter family receptor
CX034_RS17505	COG1024	Enoyl-CoA hydratase
CX034_RS17510	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX034_RS17515	COG1253	flavin adenine dinucleotide binding
CX034_RS17520	COG1285	pathogenesis
CX034_RS17530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CX034_RS17545	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CX034_RS17555	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CX034_RS17565	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX034_RS17570	COG3181	Tripartite tricarboxylate transporter family receptor
CX034_RS17575	COG1960	acyl-CoA dehydrogenase activity
CX034_RS17595	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CX034_RS17600	COG1024	Enoyl-CoA hydratase
CX034_RS17605	COG1960	acyl-CoA dehydrogenase activity
CX034_RS17625	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CX034_RS17630	COG0022	dehydrogenase e1 component
CX034_RS17635	COG1024	Enoyl-CoA hydratase
CX034_RS17640	COG0508	dehydrogenase complex catalyzes the overall conversion of
CX034_RS17660	COG0683	leucine binding
CX034_RS17665	COG0559	Belongs to the binding-protein-dependent transport system permease family
CX034_RS17670	COG0411	ABC transporter
CX034_RS17680	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CX034_RS17695	COG3181	Tripartite tricarboxylate transporter family receptor
CX034_RS17725	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CX034_RS17730	COG0793	Belongs to the peptidase S41A family
CX034_RS17735	COG4942	peptidase
CX034_RS17740	COG0588	phosphoglycerate mutase activity
CX034_RS17745	COG1054	Belongs to the UPF0176 family
CX034_RS17750	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CX034_RS17755	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CX034_RS17760	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CX034_RS17765	COG3181	Tripartite tricarboxylate transporter family receptor
CX034_RS17780	COG2226	methyltransferase
CX034_RS17785	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CX034_RS17800	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CX034_RS17805	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CX034_RS17830	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CX034_RS17855	COG1335	isochorismatase
CX034_RS17860	COG2309	aminopeptidase activity
CX034_RS17870	COG3473	Maleate cis-trans isomerase
CX034_RS17880	COG2068	MobA-Related Protein
CX034_RS17910	COG2204	response regulator
CX034_RS17915	COG5000	phosphorelay sensor kinase activity
CX034_RS17925	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CX034_RS17925	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CX034_RS17935	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
CX034_RS17970	COG0583	DNA-binding transcription factor activity
CX034_RS17990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CX034_RS17995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CX034_RS18010	COG0758	DNA mediated transformation
CX034_RS18015	COG1522	sequence-specific DNA binding
CX034_RS18025	COG0242	peptide deformylase activity
CX034_RS18040	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CX034_RS18050	COG0546	phosphoglycolate phosphatase activity
CX034_RS18070	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CX034_RS18075	COG1942	4-Oxalocrotonate Tautomerase
CX034_RS18080	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CX034_RS18105	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CX034_RS18125	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CX034_RS18130	COG1024	Enoyl-CoA hydratase
CX034_RS18135	COG1414	Transcriptional regulator
CX034_RS18140	COG0318	PFAM AMP-dependent synthetase and ligase
CX034_RS18145	COG3181	Tripartite tricarboxylate transporter family receptor
CX034_RS18190	COG3422	double-strand break repair
CX034_RS18195	COG0330	HflC and HflK could
CX034_RS18205	COG0251	oxidation-reduction process
CX034_RS18255	COG3723	Recombinational DNA repair protein, rece pathway
CX034_RS18290	COG0582	viral genome integration into host DNA
CX034_RS18325	COG0706	membrane insertase activity
CX034_RS18330	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CX034_RS18335	COG0594	ribonuclease P activity
CX034_RS18340	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CX034_RS18345	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CX034_RS18360	COG1414	Transcriptional regulator
CX034_RS18365	COG0154	amidase activity
CX034_RS18380	COG1304	FMN binding
CX034_RS18430	COG0183	Belongs to the thiolase family
CX034_RS18435	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CX034_RS18450	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CX034_RS18455	COG3181	Tripartite tricarboxylate transporter family receptor
CX034_RS18465	COG2358	TRAP transporter, solute receptor (TAXI family
CX034_RS18475	COG1629	transport
CX034_RS18480	COG2922	Belongs to the Smg family
CX034_RS18505	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CX034_RS18510	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CX034_RS18515	COG1028	Short-chain dehydrogenase reductase Sdr
CX034_RS18520	COG1012	belongs to the aldehyde dehydrogenase family
CX034_RS18530	COG0028	Belongs to the TPP enzyme family
CX034_RS18535	COG1522	sequence-specific DNA binding
CX034_RS18540	COG3781	membrane
CX034_RS18550	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CX034_RS18570	COG4206	TonB-dependent receptor
CX034_RS18575	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CX034_RS18580	COG2022	thiamine diphosphate biosynthetic process
CX034_RS18585	COG0351	phosphomethylpyrimidine kinase
CX034_RS18590	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CX034_RS18605	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CX034_RS18615	COG0628	permease
CX034_RS18625	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CX034_RS18640	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CX034_RS18645	COG0049	tRNA binding
CX034_RS18650	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CX034_RS18655	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CX034_RS18660	COG0051	transcription antitermination factor activity, RNA binding
CX034_RS18665	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CX034_RS18670	COG0088	Forms part of the polypeptide exit tunnel
CX034_RS18675	COG0089	rRNA binding
CX034_RS18680	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CX034_RS18685	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CX034_RS18690	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CX034_RS18695	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CX034_RS18700	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CX034_RS18705	COG0255	Belongs to the universal ribosomal protein uL29 family
CX034_RS18710	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CX034_RS18730	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CX034_RS18735	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CX034_RS18740	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CX034_RS18745	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CX034_RS18750	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CX034_RS18755	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CX034_RS18760	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CX034_RS18765	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CX034_RS18770	COG1841	ribosomal large subunit assembly
CX034_RS18775	COG0200	Binds to the 23S rRNA
CX034_RS18780	COG0201	protein transport
CX034_RS18785	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CX034_RS18790	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CX034_RS18795	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CX034_RS18800	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CX034_RS18805	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CX034_RS18810	COG0202	RNA polymerase activity
CX034_RS18815	COG0203	ribosomal protein L17
CX034_RS18820	COG0537	adenosine 5'-monophosphoramidase activity
CX034_RS18825	COG1324	tolerance protein
CX034_RS18830	COG4232	protein-disulfide reductase activity
CX034_RS18845	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CX034_RS18855	COG1333	cytochrome c biogenesis protein
CX034_RS18860	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CX034_RS18875	COG1965	Belongs to the frataxin family
CX034_RS18885	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CX034_RS18890	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CX034_RS18895	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CX034_RS18910	COG2814	Major facilitator Superfamily
CX034_RS18915	COG0629	single-stranded DNA binding
CX034_RS18955	COG0402	S-adenosylhomocysteine deaminase activity
CX034_RS18965	COG0438	transferase activity, transferring glycosyl groups
CX034_RS18985	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CX034_RS19010	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CX034_RS19035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CX034_RS19040	COG1956	GAF domain-containing protein
CX034_RS19045	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CX034_RS19060	COG1652	LysM domain
CX034_RS19075	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CX034_RS19090	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CX034_RS19120	COG3181	Tripartite tricarboxylate transporter family receptor
CX034_RS19135	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CX034_RS19150	COG1024	Enoyl-CoA hydratase
CX034_RS19165	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX034_RS19170	COG1309	transcriptional regulator
CX034_RS19175	COG2816	NAD+ diphosphatase activity
CX034_RS19180	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CX034_RS19265	COG2814	Major facilitator Superfamily
CX034_RS19270	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CX034_RS19290	COG1999	signal sequence binding
CX034_RS19295	COG0109	protoheme IX farnesyltransferase activity
CX034_RS19335	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CX034_RS19355	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CX034_RS19360	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CX034_RS19370	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CX034_RS19375	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CX034_RS19385	COG0070	glutamate synthase
CX034_RS19385	COG0069	glutamate synthase activity
CX034_RS19385	COG0067	glutamate synthase
CX034_RS19395	COG3047	cAMP biosynthetic process
CX034_RS19405	COG1127	ABC transporter
CX034_RS19410	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CX034_RS19415	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CX034_RS19420	COG2853	Lipoprotein
CX034_RS19435	COG0842	Transport permease protein
CX034_RS19445	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CX034_RS19450	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CX034_RS19455	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CX034_RS19460	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CX034_RS19465	COG0131	Imidazoleglycerol-phosphate dehydratase
CX034_RS19470	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CX034_RS19475	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CX034_RS19480	COG0107	imidazoleglycerol-phosphate synthase activity
CX034_RS19485	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CX034_RS19490	COG0140	phosphoribosyl-ATP diphosphatase activity
CX034_RS19495	COG0537	adenosine 5'-monophosphoramidase activity
CX034_RS19500	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CX034_RS19505	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CX034_RS19520	COG3181	Tripartite tricarboxylate transporter family receptor
CX034_RS19555	COG3702	type iv secretory pathway
CX034_RS19560	COG3451	type IV secretory pathway VirB4
CX034_RS19575	COG3736	Type IV secretory pathway, component VirB8
CX034_RS19580	COG3504	Conjugal transfer protein
CX034_RS19585	COG2948	multi-organism process
CX034_RS19590	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
CX034_RS19600	COG0697	spore germination
CX034_RS19620	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CX034_RS19625	COG0747	negative chemotaxis
CX034_RS19630	COG0601	transmembrane transport
CX034_RS19635	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CX034_RS19650	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CX034_RS19660	COG0494	nUDIX hydrolase
CX034_RS19705	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
CX034_RS19710	COG0237	dephospho-CoA kinase activity
CX034_RS19715	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CX034_RS19730	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CX034_RS19735	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CX034_RS19745	COG0477	Major facilitator Superfamily
CX034_RS19750	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CX034_RS19765	COG1126	abc transporter atp-binding protein
CX034_RS19770	COG0765	amino acid transport
CX034_RS19775	COG4597	amino acid ABC transporter
CX034_RS19780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CX034_RS19785	COG2884	Cell division ATP-binding protein ftsE
CX034_RS19790	COG2177	Part of the ABC transporter FtsEX involved in
CX034_RS19795	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CX034_RS19805	COG1194	a g-specific adenine glycosylase
CX034_RS19815	COG2226	methyltransferase
CX034_RS19825	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX034_RS19830	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX034_RS19845	COG1024	Enoyl-CoA hydratase
CX034_RS19865	COG1024	Enoyl-CoA hydratase
CX034_RS19870	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX034_RS19885	COG0753	catalase activity
CX034_RS19890	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CX034_RS19895	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CX034_RS19905	COG2175	clavaminate synthase activity
CX034_RS19910	COG1473	amidohydrolase
CX034_RS19915	COG4608	Belongs to the ABC transporter superfamily
CX034_RS19920	COG0444	Belongs to the ABC transporter superfamily
CX034_RS19935	COG0747	negative chemotaxis
CX034_RS19940	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CX034_RS19975	COG0436	Aminotransferase
CX034_RS19980	COG1278	Cold shock