locus-tag	class	description
XA10_RS00005	COG0445	tRNA wobble uridine modification
XA10_RS00010	COG0357	Ribosomal RNA small subunit methyltransferase G
XA10_RS00015	COG1192	Involved in chromosome partitioning
XA10_RS00025	COG1475	DNA binding
XA10_RS00030	COG0252	asparaginase activity
XA10_RS00055	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
XA10_RS00065	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
XA10_RS00075	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
XA10_RS00080	COG0081	regulation of translation
XA10_RS00085	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
XA10_RS00090	COG0222	ribosome binding
XA10_RS00095	COG0085	RNA polymerase activity
XA10_RS00100	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
XA10_RS00140	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XA10_RS00165	COG1024	Enoyl-CoA hydratase
XA10_RS00185	COG0752	glycyl-tRNA synthetase alpha subunit
XA10_RS00190	COG0751	glycine-tRNA ligase activity
XA10_RS00195	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
XA10_RS00200	COG0204	Acyl-transferase
XA10_RS00215	COG0242	peptide deformylase activity
XA10_RS00250	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
XA10_RS00255	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XA10_RS00260	COG2813	Specifically methylates the guanine in position
XA10_RS00260	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XA10_RS00275	COG2223	nitrite transmembrane transporter activity
XA10_RS00285	COG1794	racemase activity, acting on amino acids and derivatives
XA10_RS00290	COG1126	abc transporter atp-binding protein
XA10_RS00295	COG0765	amino acid transport
XA10_RS00300	COG0765	amino acid transport
XA10_RS00305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XA10_RS00370	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XA10_RS00400	COG0326	Molecular chaperone. Has ATPase activity
XA10_RS00405	COG0625	glutathione transferase activity
XA10_RS00420	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XA10_RS00425	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
XA10_RS00455	COG0438	transferase activity, transferring glycosyl groups
XA10_RS00460	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
XA10_RS00465	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
XA10_RS00495	COG0859	PFAM glycosyl transferase family 9
XA10_RS00510	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
XA10_RS00520	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XA10_RS00525	COG1127	ABC transporter
XA10_RS00545	COG1686	Belongs to the peptidase S11 family
XA10_RS00555	COG2921	Belongs to the UPF0250 family
XA10_RS00560	COG0321	lipoyl(octanoyl) transferase activity
XA10_RS00565	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
XA10_RS00600	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XA10_RS00610	COG0018	arginyl-trna synthetase
XA10_RS00630	COG0395	ABC-type sugar transport system, permease component
XA10_RS00635	COG1175	transmembrane transport
XA10_RS00640	COG1653	transport
XA10_RS00645	COG3842	ATPase activity
XA10_RS00650	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
XA10_RS00725	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
XA10_RS00730	COG2816	NAD+ diphosphatase activity
XA10_RS00735	COG1309	transcriptional regulator
XA10_RS00740	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XA10_RS00755	COG1024	Enoyl-CoA hydratase
XA10_RS00770	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XA10_RS00785	COG3181	Tripartite tricarboxylate transporter family receptor
XA10_RS00815	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
XA10_RS00830	COG0220	tRNA (guanine-N7-)-methyltransferase activity
XA10_RS00845	COG1652	LysM domain
XA10_RS00860	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XA10_RS00865	COG1956	GAF domain-containing protein
XA10_RS00870	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XA10_RS00890	COG2186	Transcriptional regulator
XA10_RS00895	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
XA10_RS00920	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XA10_RS00940	COG0438	transferase activity, transferring glycosyl groups
XA10_RS00950	COG0402	S-adenosylhomocysteine deaminase activity
XA10_RS00990	COG0629	single-stranded DNA binding
XA10_RS00995	COG2814	Major facilitator Superfamily
XA10_RS01010	COG0232	Belongs to the dGTPase family. Type 2 subfamily
XA10_RS01015	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
XA10_RS01020	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
XA10_RS01030	COG1965	Belongs to the frataxin family
XA10_RS01045	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XA10_RS01050	COG1333	cytochrome c biogenesis protein
XA10_RS01060	COG0218	Necessary for normal cell division and for the maintenance of normal septation
XA10_RS01075	COG4232	protein-disulfide reductase activity
XA10_RS01080	COG1324	tolerance protein
XA10_RS01085	COG0537	adenosine 5'-monophosphoramidase activity
XA10_RS01090	COG0203	ribosomal protein L17
XA10_RS01095	COG0202	RNA polymerase activity
XA10_RS01100	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
XA10_RS01105	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
XA10_RS01110	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
XA10_RS01115	COG0257	Belongs to the bacterial ribosomal protein bL36 family
XA10_RS01120	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
XA10_RS01125	COG0201	protein transport
XA10_RS01130	COG0200	Binds to the 23S rRNA
XA10_RS01135	COG1841	ribosomal large subunit assembly
XA10_RS01140	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
XA10_RS01145	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
XA10_RS01150	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
XA10_RS01155	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
XA10_RS01160	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
XA10_RS01165	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
XA10_RS01170	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
XA10_RS01175	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
XA10_RS01195	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
XA10_RS01200	COG0255	Belongs to the universal ribosomal protein uL29 family
XA10_RS01205	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
XA10_RS01210	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
XA10_RS01215	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
XA10_RS01220	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
XA10_RS01225	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
XA10_RS01230	COG0089	rRNA binding
XA10_RS01235	COG0088	Forms part of the polypeptide exit tunnel
XA10_RS01240	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
XA10_RS01245	COG0051	transcription antitermination factor activity, RNA binding
XA10_RS01250	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
XA10_RS01255	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
XA10_RS01260	COG0049	tRNA binding
XA10_RS01265	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
XA10_RS01275	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XA10_RS01285	COG0628	permease
XA10_RS01295	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
XA10_RS01305	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XA10_RS01310	COG0351	phosphomethylpyrimidine kinase
XA10_RS01315	COG2022	thiamine diphosphate biosynthetic process
XA10_RS01320	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
XA10_RS01325	COG4206	TonB-dependent receptor
XA10_RS01345	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
XA10_RS01355	COG3781	membrane
XA10_RS01360	COG1522	sequence-specific DNA binding
XA10_RS01365	COG0028	Belongs to the TPP enzyme family
XA10_RS01375	COG1012	belongs to the aldehyde dehydrogenase family
XA10_RS01380	COG1028	Short-chain dehydrogenase reductase Sdr
XA10_RS01385	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XA10_RS01390	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
XA10_RS01415	COG2922	Belongs to the Smg family
XA10_RS01420	COG1629	transport
XA10_RS01430	COG2358	TRAP transporter, solute receptor (TAXI family
XA10_RS01440	COG3181	Tripartite tricarboxylate transporter family receptor
XA10_RS01445	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
XA10_RS01460	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XA10_RS01475	COG1960	acyl-CoA dehydrogenase activity
XA10_RS01495	COG1960	acyl-CoA dehydrogenase activity
XA10_RS01515	COG1304	FMN binding
XA10_RS01530	COG0154	amidase activity
XA10_RS01535	COG1414	Transcriptional regulator
XA10_RS01550	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
XA10_RS01555	COG0230	Belongs to the bacterial ribosomal protein bL34 family
XA10_RS01560	COG0594	ribonuclease P activity
XA10_RS01565	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
XA10_RS01570	COG0706	membrane insertase activity
XA10_RS01580	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
XA10_RS01605	COG0582	viral genome integration into host DNA
XA10_RS01640	COG3723	Recombinational DNA repair protein, rece pathway
XA10_RS01685	COG0251	oxidation-reduction process
XA10_RS01695	COG0330	HflC and HflK could
XA10_RS01700	COG3422	double-strand break repair
XA10_RS01715	COG0583	DNA-binding transcription factor activity
XA10_RS01745	COG3181	Tripartite tricarboxylate transporter family receptor
XA10_RS01750	COG0318	PFAM AMP-dependent synthetase and ligase
XA10_RS01755	COG1414	Transcriptional regulator
XA10_RS01760	COG1024	Enoyl-CoA hydratase
XA10_RS01765	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XA10_RS01785	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
XA10_RS01805	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XA10_RS01810	COG1942	4-Oxalocrotonate Tautomerase
XA10_RS01815	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XA10_RS01835	COG0546	phosphoglycolate phosphatase activity
XA10_RS01845	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
XA10_RS01860	COG0242	peptide deformylase activity
XA10_RS01870	COG1522	sequence-specific DNA binding
XA10_RS01875	COG0758	DNA mediated transformation
XA10_RS01890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XA10_RS01895	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XA10_RS01900	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
XA10_RS01915	COG0583	DNA-binding transcription factor activity
XA10_RS01940	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
XA10_RS01950	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
XA10_RS01950	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XA10_RS01960	COG5000	phosphorelay sensor kinase activity
XA10_RS01965	COG2204	response regulator
XA10_RS01990	COG2068	MobA-Related Protein
XA10_RS02000	COG3473	Maleate cis-trans isomerase
XA10_RS02005	COG0596	Alpha beta hydrolase
XA10_RS02010	COG2309	aminopeptidase activity
XA10_RS02015	COG1335	isochorismatase
XA10_RS02040	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
XA10_RS02065	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
XA10_RS02070	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XA10_RS02085	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
XA10_RS02090	COG2226	methyltransferase
XA10_RS02105	COG3181	Tripartite tricarboxylate transporter family receptor
XA10_RS02110	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
XA10_RS02115	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
XA10_RS02120	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
XA10_RS02125	COG1054	Belongs to the UPF0176 family
XA10_RS02130	COG0588	phosphoglycerate mutase activity
XA10_RS02135	COG4942	peptidase
XA10_RS02140	COG0793	Belongs to the peptidase S41A family
XA10_RS02145	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
XA10_RS02170	COG3181	Tripartite tricarboxylate transporter family receptor
XA10_RS02185	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XA10_RS02195	COG0411	ABC transporter
XA10_RS02200	COG0559	Belongs to the binding-protein-dependent transport system permease family
XA10_RS02205	COG0683	leucine binding
XA10_RS02225	COG0508	dehydrogenase complex catalyzes the overall conversion of
XA10_RS02230	COG1024	Enoyl-CoA hydratase
XA10_RS02235	COG0022	dehydrogenase e1 component
XA10_RS02240	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
XA10_RS02260	COG1960	acyl-CoA dehydrogenase activity
XA10_RS02265	COG1024	Enoyl-CoA hydratase
XA10_RS02270	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XA10_RS02290	COG1960	acyl-CoA dehydrogenase activity
XA10_RS02295	COG3181	Tripartite tricarboxylate transporter family receptor
XA10_RS02300	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XA10_RS02310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XA10_RS02335	COG3181	Tripartite tricarboxylate transporter family receptor
XA10_RS02345	COG0277	FAD linked oxidase domain protein
XA10_RS02350	COG1960	acyl-CoA dehydrogenase activity
XA10_RS02355	COG1960	acyl-CoA dehydrogenase activity
XA10_RS02365	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XA10_RS02385	COG0604	alcohol dehydrogenase
XA10_RS02400	COG1024	Enoyl-CoA hydratase
XA10_RS02420	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XA10_RS02425	COG1522	sequence-specific DNA binding
XA10_RS02430	COG0183	Belongs to the thiolase family
XA10_RS02440	COG1960	acyl-CoA dehydrogenase activity
XA10_RS02485	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
XA10_RS02490	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
XA10_RS02495	COG2890	protein-(glutamine-N5) methyltransferase activity
XA10_RS02500	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XA10_RS02510	COG3181	Tripartite tricarboxylate transporter family receptor
XA10_RS02545	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
XA10_RS02550	COG1660	Displays ATPase and GTPase activities
XA10_RS02560	COG2010	Cytochrome c
XA10_RS02560	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XA10_RS02565	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
XA10_RS02575	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
XA10_RS02580	COG1137	ATPase activity
XA10_RS02595	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
XA10_RS02605	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
XA10_RS02640	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
XA10_RS02645	COG3568	Endonuclease Exonuclease Phosphatase
XA10_RS02650	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XA10_RS02680	COG0154	amidase activity
XA10_RS02690	COG1414	Transcriptional regulator
XA10_RS02700	COG1250	3-hydroxyacyl-CoA dehydrogenase
XA10_RS02700	COG1024	Enoyl-CoA hydratase
XA10_RS02710	COG2132	Multicopper oxidase
XA10_RS02740	COG1250	3-hydroxyacyl-CoA dehydrogenase
XA10_RS02765	COG1024	Enoyl-CoA hydratase
XA10_RS02770	COG1024	Enoyl-CoA hydratase
XA10_RS02775	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XA10_RS02795	COG0601	transmembrane transport
XA10_RS02800	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XA10_RS02805	COG4172	Belongs to the ABC transporter superfamily
XA10_RS02815	COG2195	Cleaves the N-terminal amino acid of tripeptides
XA10_RS02825	COG0210	DNA helicase
XA10_RS02830	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
XA10_RS02835	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
XA10_RS02845	COG0355	proton-transporting ATP synthase activity, rotational mechanism
XA10_RS02850	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
XA10_RS02855	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
XA10_RS02860	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
XA10_RS02865	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
XA10_RS02870	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
XA10_RS02880	COG0356	it plays a direct role in the translocation of protons across the membrane
XA10_RS02905	COG1024	Enoyl-CoA hydratase
XA10_RS02910	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XA10_RS02915	COG3634	alkyl hydroperoxide reductase activity
XA10_RS02925	COG0037	tRNA processing
XA10_RS02935	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XA10_RS02940	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XA10_RS02945	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XA10_RS02950	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
XA10_RS02955	COG2967	ApaG domain
XA10_RS02960	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
XA10_RS02965	COG0546	phosphoglycolate phosphatase activity
XA10_RS02975	COG0512	Glutamine amidotransferase of anthranilate synthase
XA10_RS02980	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
XA10_RS02985	COG0134	indole-3-glycerol-phosphate synthase activity
XA10_RS03005	COG1960	acyl-CoA dehydrogenase activity
XA10_RS03010	COG0583	DNA-binding transcription factor activity
XA10_RS03025	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
XA10_RS03030	COG0259	pyridoxamine-phosphate oxidase activity
XA10_RS03040	COG2814	Major facilitator Superfamily
XA10_RS03045	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
XA10_RS03050	COG2188	Transcriptional regulator
XA10_RS03055	COG0318	PFAM AMP-dependent synthetase and ligase
XA10_RS03075	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XA10_RS03085	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
XA10_RS03100	COG1215	transferase activity, transferring glycosyl groups
XA10_RS03110	COG0601	transmembrane transport
XA10_RS03125	COG0488	(ABC) transporter
XA10_RS03145	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
XA10_RS03150	COG2894	cell division
XA10_RS03155	COG0850	regulation of cytokinetic process
XA10_RS03160	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XA10_RS03165	COG1271	oxidase subunit
XA10_RS03200	COG2979	Protein of unknown function (DUF533)
XA10_RS03220	COG0741	lytic transglycosylase activity
XA10_RS03220	COG1388	LysM domain
XA10_RS03225	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XA10_RS03230	COG2226	methyltransferase
XA10_RS03235	COG0328	RNA-DNA hybrid ribonuclease activity
XA10_RS03285	COG2030	dehydratase
XA10_RS03290	COG0183	Belongs to the thiolase family
XA10_RS03335	COG1960	acyl-CoA dehydrogenase activity
XA10_RS03350	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XA10_RS03355	COG1028	Short-chain dehydrogenase reductase Sdr
XA10_RS03370	COG2718	Belongs to the UPF0229 family
XA10_RS03375	COG2719	SpoVR family
XA10_RS03400	COG2188	Transcriptional regulator
XA10_RS03415	COG0633	Ferredoxin
XA10_RS03425	COG0829	nickel cation binding
XA10_RS03430	COG0831	urea catabolic process
XA10_RS03440	COG0832	Belongs to the urease beta subunit family
XA10_RS03445	COG0804	urea catabolic process
XA10_RS03455	COG0830	nickel cation binding
XA10_RS03460	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
XA10_RS03480	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XA10_RS03485	COG0601	transmembrane transport
XA10_RS03490	COG0747	negative chemotaxis
XA10_RS03500	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
XA10_RS03505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XA10_RS03515	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
XA10_RS03525	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
XA10_RS03530	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XA10_RS03535	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
XA10_RS03550	COG0438	transferase activity, transferring glycosyl groups
XA10_RS03565	COG0438	transferase activity, transferring glycosyl groups
XA10_RS03570	COG0438	transferase activity, transferring glycosyl groups
XA10_RS03575	COG0166	Belongs to the GPI family
XA10_RS03590	COG0277	FAD linked oxidase domain protein
XA10_RS03595	COG0745	RESPONSE REGULATOR receiver
XA10_RS03600	COG0642	Histidine kinase
XA10_RS03605	COG1368	sulfuric ester hydrolase activity
XA10_RS03615	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
XA10_RS03640	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
XA10_RS03650	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
XA10_RS03655	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
XA10_RS03665	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
XA10_RS03670	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
XA10_RS03675	COG0193	aminoacyl-tRNA hydrolase activity
XA10_RS03685	COG0012	GTP binding
XA10_RS03690	COG0582	viral genome integration into host DNA
XA10_RS03715	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
XA10_RS03775	COG0745	RESPONSE REGULATOR receiver
XA10_RS03790	COG1309	transcriptional regulator
XA10_RS03820	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XA10_RS03830	COG0405	Gamma-glutamyltransferase
XA10_RS03845	COG1280	lysine exporter protein (LysE YggA)
XA10_RS03905	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
XA10_RS03910	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XA10_RS03920	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
XA10_RS03925	COG0513	Belongs to the DEAD box helicase family
XA10_RS03935	COG0617	tRNA 3'-terminal CCA addition
XA10_RS03950	COG0477	Major facilitator Superfamily
XA10_RS03960	COG0583	DNA-binding transcription factor activity
XA10_RS03975	COG1950	PFAM Membrane protein of
XA10_RS03980	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
XA10_RS03995	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
XA10_RS04005	COG1560	Kdo2-lipid A biosynthetic process
XA10_RS04010	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
XA10_RS04020	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XA10_RS04030	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
XA10_RS04040	COG0803	Belongs to the bacterial solute-binding protein 9 family
XA10_RS04060	COG0735	belongs to the Fur family
XA10_RS04065	COG0523	cobalamin synthesis protein
XA10_RS04075	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
XA10_RS04080	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
XA10_RS04090	COG2096	Adenosyltransferase
XA10_RS04105	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
XA10_RS04110	COG2084	Dehydrogenase
XA10_RS04165	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
XA10_RS04170	COG0129	dihydroxy-acid dehydratase activity
XA10_RS04175	COG4654	Cytochrome c, class I
XA10_RS04180	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
XA10_RS04230	COG1473	amidohydrolase
XA10_RS04235	COG0418	dihydroorotase activity
XA10_RS04240	COG0488	(ABC) transporter
XA10_RS04250	COG2001	Belongs to the MraZ family
XA10_RS04255	COG0275	rRNA processing
XA10_RS04260	COG3116	cell division
XA10_RS04270	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
XA10_RS04275	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XA10_RS04280	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
XA10_RS04290	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
XA10_RS04295	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XA10_RS04300	COG1181	Belongs to the D-alanine--D-alanine ligase family
XA10_RS04305	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
XA10_RS04315	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
XA10_RS04320	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
XA10_RS04330	COG0739	heme binding
XA10_RS04335	COG0653	protein targeting
XA10_RS04355	COG1028	Short-chain dehydrogenase reductase Sdr
XA10_RS04360	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XA10_RS04365	COG1522	sequence-specific DNA binding
XA10_RS04385	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
XA10_RS04395	COG0557	exoribonuclease II activity
XA10_RS04400	COG3150	esterase
XA10_RS04405	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XA10_RS04410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XA10_RS04415	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
XA10_RS04420	COG0511	ligase activity, forming carbon-carbon bonds
XA10_RS04425	COG0439	Biotin carboxylase
XA10_RS04430	COG2264	protein methyltransferase activity
XA10_RS04440	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XA10_RS04465	COG1696	Membrane protein involved in D-alanine export
XA10_RS04470	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XA10_RS04505	COG1522	sequence-specific DNA binding
XA10_RS04520	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XA10_RS04525	COG0045	succinate-CoA ligase (ADP-forming) activity
XA10_RS04525	COG1042	CoA-binding domain protein
XA10_RS04525	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XA10_RS04540	COG1802	Transcriptional regulator
XA10_RS04545	COG3069	C4-dicarboxylate transmembrane transporter activity
XA10_RS04550	COG0513	Belongs to the DEAD box helicase family
XA10_RS04555	COG0346	lactoylglutathione lyase activity
XA10_RS04560	COG1335	isochorismatase
XA10_RS04565	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XA10_RS04570	COG1116	anion transmembrane transporter activity
XA10_RS04585	COG3028	Belongs to the UPF0307 family
XA10_RS04590	COG0312	modulator of DNA gyrase
XA10_RS04595	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
XA10_RS04600	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
XA10_RS04605	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
XA10_RS04610	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
XA10_RS04620	COG0316	Belongs to the HesB IscA family
XA10_RS04625	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
XA10_RS04640	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
XA10_RS04650	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
XA10_RS04655	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
XA10_RS04670	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XA10_RS04670	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XA10_RS04700	COG0583	DNA-binding transcription factor activity
XA10_RS04705	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XA10_RS04740	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
XA10_RS04750	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XA10_RS04755	COG1845	cytochrome c oxidase, subunit III
XA10_RS04760	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
XA10_RS04765	COG0640	Transcriptional regulator
XA10_RS04785	COG3220	belongs to the UPF0276 family
XA10_RS04830	COG1666	GTP binding
XA10_RS04865	COG0312	modulator of DNA gyrase
XA10_RS04870	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
XA10_RS04875	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
XA10_RS04875	COG3064	Membrane
XA10_RS04875	COG3210	domain, Protein
XA10_RS04875	COG3064	Membrane
XA10_RS04875	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
XA10_RS04875	COG3210	domain, Protein
XA10_RS04880	COG0277	FAD linked oxidase domain protein
XA10_RS04885	COG0277	FAD linked oxidase domain protein
XA10_RS04890	COG0277	FAD linked oxidase domain protein
XA10_RS04895	COG0247	lactate metabolic process
XA10_RS04900	COG2819	hydrolase of the alpha beta superfamily
XA10_RS04925	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
XA10_RS04945	COG0583	DNA-binding transcription factor activity
XA10_RS04950	COG0482	sulfurtransferase activity
XA10_RS04955	COG0730	response to heat
XA10_RS04960	COG0625	glutathione transferase activity
XA10_RS04965	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
XA10_RS04970	COG3909	cytochrome
XA10_RS05010	COG0154	amidase activity
XA10_RS05015	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XA10_RS05020	COG1024	Enoyl-CoA hydratase
XA10_RS05035	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XA10_RS05050	COG1028	Short-chain dehydrogenase reductase Sdr
XA10_RS05055	COG1414	Transcriptional regulator
XA10_RS05065	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
XA10_RS05070	COG0251	oxidation-reduction process
XA10_RS05075	COG0559	Belongs to the binding-protein-dependent transport system permease family
XA10_RS05095	COG1902	pentaerythritol trinitrate reductase activity
XA10_RS05110	COG0583	DNA-binding transcription factor activity
XA10_RS05120	COG0590	tRNA wobble adenosine to inosine editing
XA10_RS05125	COG2807	transmembrane transport
XA10_RS05145	COG0154	amidase activity
XA10_RS05150	COG0307	riboflavin synthase, alpha
XA10_RS05155	COG3181	Tripartite tricarboxylate transporter family receptor
XA10_RS05160	COG1522	sequence-specific DNA binding
XA10_RS05170	COG0318	PFAM AMP-dependent synthetase and ligase
XA10_RS05180	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XA10_RS05200	COG1063	alcohol dehydrogenase
XA10_RS05225	COG1418	mRNA catabolic process
XA10_RS05230	COG1448	Aminotransferase
XA10_RS05235	COG0583	DNA-binding transcription factor activity
XA10_RS05245	COG0477	Major facilitator Superfamily
XA10_RS05250	COG1028	Short-chain dehydrogenase reductase Sdr
XA10_RS05265	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
XA10_RS05270	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
XA10_RS05275	COG0583	DNA-binding transcription factor activity
XA10_RS05335	COG1028	Short-chain dehydrogenase reductase Sdr
XA10_RS05340	COG1309	transcriptional regulator
XA10_RS05350	COG2982	Protein involved in outer membrane biogenesis
XA10_RS05355	COG2818	Glycosylase
XA10_RS05375	COG1653	transport
XA10_RS05385	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XA10_RS05390	COG3842	ATPase activity
XA10_RS05395	COG0395	ABC-type sugar transport system, permease component
XA10_RS05400	COG1175	transmembrane transport
XA10_RS05415	COG3181	Tripartite tricarboxylate transporter family receptor
XA10_RS05420	COG2186	Transcriptional regulator
XA10_RS05450	COG1454	alcohol dehydrogenase
XA10_RS05470	COG2011	ABC-type metal ion transport system permease component
XA10_RS05475	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
XA10_RS05480	COG1501	Belongs to the glycosyl hydrolase 31 family
XA10_RS05505	COG0318	PFAM AMP-dependent synthetase and ligase
XA10_RS05510	COG1473	amidohydrolase
XA10_RS05520	COG2855	membrane
XA10_RS05530	COG2239	Acts as a magnesium transporter
XA10_RS05550	COG3181	Tripartite tricarboxylate transporter family receptor
XA10_RS05560	COG1722	exodeoxyribonuclease VII activity
XA10_RS05565	COG0142	geranyltranstransferase activity
XA10_RS05570	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
XA10_RS05575	COG1469	GTP cyclohydrolase I activity
XA10_RS05580	COG0360	Binds together with S18 to 16S ribosomal RNA
XA10_RS05585	COG2965	DNA replication, synthesis of RNA primer
XA10_RS05590	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
XA10_RS05595	COG0359	binds to the 23S rRNA
XA10_RS05605	COG0305	Participates in initiation and elongation during chromosome replication
XA10_RS05615	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
XA10_RS05620	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
XA10_RS05625	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
XA10_RS05630	COG3737	Protein of unknown function (DUF498/DUF598)
XA10_RS05635	COG0436	Aminotransferase
XA10_RS05660	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
XA10_RS05690	COG0268	Binds directly to 16S ribosomal RNA
XA10_RS05700	COG0728	peptidoglycan biosynthetic process
XA10_RS05710	COG0563	adenylate kinase activity
XA10_RS05715	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
XA10_RS05720	COG2835	tetraacyldisaccharide 4'-kinase activity
XA10_RS05725	COG1663	tetraacyldisaccharide 4'-kinase activity
XA10_RS05730	COG0848	biopolymer transport protein
XA10_RS05735	COG0811	peptide transport
XA10_RS05745	COG1570	exodeoxyribonuclease VII activity
XA10_RS05750	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XA10_RS05755	COG0038	chloride channel
XA10_RS05760	COG0183	Belongs to the thiolase family
XA10_RS05770	COG1278	Cold shock
XA10_RS05775	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
XA10_RS05785	COG4953	penicillin-binding protein 1C
XA10_RS05790	COG0542	response to heat
XA10_RS05795	COG2995	paraquat-inducible protein a
XA10_RS05800	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XA10_RS05800	COG3008	intermembrane lipid transfer
XA10_RS05810	COG0506	proline dehydrogenase activity
XA10_RS05810	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
XA10_RS05810	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
XA10_RS05845	COG2271	Major facilitator Superfamily
XA10_RS05850	COG1309	transcriptional regulator
XA10_RS05860	COG3468	outer membrane autotransporter barrel domain protein
XA10_RS05890	COG0477	Major facilitator Superfamily
XA10_RS05900	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XA10_RS05905	COG1845	cytochrome c oxidase, subunit III
XA10_RS05910	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
XA10_RS05920	COG1028	Short-chain dehydrogenase reductase Sdr
XA10_RS05940	COG0789	Transcriptional regulator
XA10_RS05965	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
XA10_RS05970	COG0697	spore germination
XA10_RS05980	COG0678	peroxiredoxin activity
XA10_RS05990	COG0412	Dienelactone hydrolase
XA10_RS06000	COG0315	cyclic pyranopterin monophosphate synthase activity
XA10_RS06015	COG0521	Mo-molybdopterin cofactor biosynthetic process
XA10_RS06020	COG0303	'Molybdopterin
XA10_RS06025	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
XA10_RS06045	COG0165	Argininosuccinate lyase
XA10_RS06050	COG0668	transmembrane transport
XA10_RS06095	COG0747	negative chemotaxis
XA10_RS06100	COG0601	transmembrane transport
XA10_RS06105	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XA10_RS06110	COG1162	GTPase activity
XA10_RS06115	COG0501	Belongs to the peptidase M48B family
XA10_RS06120	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
XA10_RS06130	COG3327	negative regulation of DNA-templated transcription, initiation
XA10_RS06135	COG3396	Phenylacetate-CoA oxygenase
XA10_RS06140	COG3460	Phenylacetate-CoA oxygenase
XA10_RS06145	COG3396	Phenylacetate-CoA oxygenase
XA10_RS06150	COG2151	metal-sulfur cluster biosynthetic enzyme
XA10_RS06155	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
XA10_RS06165	COG1012	belongs to the aldehyde dehydrogenase family
XA10_RS06170	COG1024	Enoyl-CoA hydratase
XA10_RS06175	COG2050	protein possibly involved in aromatic compounds catabolism
XA10_RS06185	COG3539	Fimbrial protein
XA10_RS06205	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XA10_RS06210	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
XA10_RS06210	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
XA10_RS06215	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
XA10_RS06220	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
XA10_RS06220	COG0047	phosphoribosylformylglycinamidine synthase activity
XA10_RS06225	COG3210	domain, Protein
XA10_RS06225	COG3064	Membrane
XA10_RS06225	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
XA10_RS06250	COG0235	Class ii aldolase
XA10_RS06255	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
XA10_RS06260	COG0720	synthase
XA10_RS06265	COG0602	queuosine metabolic process
XA10_RS06290	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XA10_RS06325	COG3181	Tripartite tricarboxylate transporter family receptor
XA10_RS06355	COG3842	ATPase activity
XA10_RS06365	COG0395	ABC-type sugar transport system, permease component
XA10_RS06395	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XA10_RS06400	COG0420	3'-5' exonuclease activity
XA10_RS06445	COG0519	Catalyzes the synthesis of GMP from XMP
XA10_RS06445	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XA10_RS06460	COG3550	peptidyl-serine autophosphorylation
XA10_RS06470	COG0477	Major facilitator Superfamily
XA10_RS06485	COG1228	amidohydrolase
XA10_RS06495	COG1116	anion transmembrane transporter activity
XA10_RS06500	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XA10_RS06540	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
XA10_RS06560	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
XA10_RS06590	COG2814	Major facilitator Superfamily
XA10_RS06605	COG1280	lysine exporter protein (LysE YggA)
XA10_RS06620	COG0747	negative chemotaxis
XA10_RS06625	COG0601	transmembrane transport
XA10_RS06630	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XA10_RS06635	COG4172	Belongs to the ABC transporter superfamily
XA10_RS06640	COG1609	Transcriptional regulator
XA10_RS06670	COG0586	Pfam SNARE associated Golgi protein
XA10_RS06685	COG0500	methyltransferase
XA10_RS06700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XA10_RS06710	COG0756	dUTP diphosphatase activity
XA10_RS06725	COG0291	Belongs to the bacterial ribosomal protein bL35 family
XA10_RS06730	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
XA10_RS06735	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
XA10_RS06740	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XA10_RS06740	COG0072	phenylalanine-tRNA ligase activity
XA10_RS06745	COG0776	regulation of translation
XA10_RS06815	COG0540	Belongs to the ATCase OTCase family
XA10_RS06820	COG2974	May be involved in recombination
XA10_RS06830	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XA10_RS06835	COG0583	DNA-binding transcription factor activity
XA10_RS06855	COG1028	Short-chain dehydrogenase reductase Sdr
XA10_RS06870	COG3842	ATPase activity
XA10_RS06875	COG1024	Enoyl-CoA hydratase
XA10_RS06875	COG1250	3-hydroxyacyl-CoA dehydrogenase
XA10_RS06895	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
XA10_RS06900	COG2137	regulation of response to DNA damage stimulus
XA10_RS06910	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
XA10_RS06920	COG0045	succinate-CoA ligase (ADP-forming) activity
XA10_RS06925	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
XA10_RS06930	COG0861	Integral membrane protein TerC family
XA10_RS06935	COG0861	Integral membrane protein TerC family
XA10_RS06940	COG0181	hydroxymethylbilane synthase activity
XA10_RS07000	COG4964	Belongs to the GSP D family
XA10_RS07030	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
XA10_RS07040	COG0583	DNA-binding transcription factor activity
XA10_RS07050	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XA10_RS07055	COG4311	Sarcosine oxidase, delta subunit
XA10_RS07060	COG0404	The glycine cleavage system catalyzes the degradation of glycine
XA10_RS07060	COG0446	pyridine nucleotide-disulphide oxidoreductase
XA10_RS07095	COG0812	UDP-N-acetylmuramate dehydrogenase activity
XA10_RS07100	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
XA10_RS07105	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XA10_RS07110	COG0735	belongs to the Fur family
XA10_RS07115	COG0497	DNA recombination
XA10_RS07120	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
XA10_RS07125	COG1420	regulation of RNA biosynthetic process
XA10_RS07130	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
XA10_RS07140	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
XA10_RS07150	COG0443	Heat shock 70 kDa protein
XA10_RS07160	COG0612	Peptidase, M16
XA10_RS07180	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
XA10_RS07225	COG0745	RESPONSE REGULATOR receiver
XA10_RS07235	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
XA10_RS07240	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
XA10_RS07245	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
XA10_RS07260	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
XA10_RS07280	COG1193	negative regulation of DNA recombination
XA10_RS07285	COG0492	ferredoxin-NADP+ reductase activity
XA10_RS07290	COG1674	ftsk spoiiie
XA10_RS07295	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
XA10_RS07300	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
XA10_RS07305	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
XA10_RS07330	COG3706	GGDEF domain
XA10_RS07350	COG2814	Major facilitator Superfamily
XA10_RS07380	COG3486	L-lysine 6-monooxygenase (NADPH) activity
XA10_RS07395	COG1028	Short-chain dehydrogenase reductase Sdr
XA10_RS07405	COG3022	response to hydroperoxide
XA10_RS07415	COG1289	transmembrane transporter activity
XA10_RS07435	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XA10_RS07445	COG2197	response regulator
XA10_RS07450	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
XA10_RS07455	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
XA10_RS07460	COG0189	ligase activity
XA10_RS07470	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
XA10_RS07475	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XA10_RS07485	COG1764	response to oxidative stress
XA10_RS07490	COG2423	ornithine cyclodeaminase activity
XA10_RS07500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XA10_RS07505	COG0765	amino acid transport
XA10_RS07510	COG0765	amino acid transport
XA10_RS07515	COG1126	abc transporter atp-binding protein
XA10_RS07570	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
XA10_RS07580	COG2944	sequence-specific DNA binding
XA10_RS07590	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
XA10_RS07595	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
XA10_RS07600	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
XA10_RS07605	COG0009	L-threonylcarbamoyladenylate synthase
XA10_RS07610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XA10_RS07615	COG1414	Transcriptional regulator
XA10_RS07630	COG0765	amino acid transport
XA10_RS07635	COG1126	abc transporter atp-binding protein
XA10_RS07640	COG0028	Belongs to the TPP enzyme family
XA10_RS07655	COG0028	Belongs to the TPP enzyme family
XA10_RS07660	COG0583	DNA-binding transcription factor activity
XA10_RS07665	COG4974	Belongs to the 'phage' integrase family
XA10_RS07670	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
XA10_RS07675	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
XA10_RS07690	COG1686	Belongs to the peptidase S11 family
XA10_RS07700	COG2814	Major facilitator Superfamily
XA10_RS07710	COG1074	ATP-dependent DNA helicase activity
XA10_RS07725	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
XA10_RS07730	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
XA10_RS07735	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
XA10_RS07755	COG2321	neutral zinc metallopeptidase
XA10_RS07760	COG0009	L-threonylcarbamoyladenylate synthase
XA10_RS07805	COG3360	Dodecin
XA10_RS07810	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
XA10_RS07815	COG2850	peptidyl-arginine hydroxylation
XA10_RS07820	COG3539	Fimbrial protein
XA10_RS07825	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
XA10_RS07830	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XA10_RS07850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XA10_RS07855	COG0765	amino acid transport
XA10_RS07860	COG1126	abc transporter atp-binding protein
XA10_RS07865	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XA10_RS07870	COG1758	RNA polymerase activity
XA10_RS07875	COG0194	GDP metabolic process
XA10_RS07880	COG3258	Cytochrome c
XA10_RS07885	COG2863	cytochrome
XA10_RS07890	COG1028	Short-chain dehydrogenase reductase Sdr
XA10_RS07895	COG0791	NLP P60 protein
XA10_RS07900	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
XA10_RS07920	COG1561	YicC-like family, N-terminal region
XA10_RS07925	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
XA10_RS07940	COG0840	transmembrane signaling receptor activity
XA10_RS07945	COG2199	diguanylate cyclase activity
XA10_RS07945	COG2200	EAL domain
XA10_RS07950	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
XA10_RS07960	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XA10_RS07965	COG0174	glutamine synthetase
XA10_RS07975	COG2204	response regulator
XA10_RS07980	COG0583	DNA-binding transcription factor activity
XA10_RS07985	COG1741	Belongs to the pirin family
XA10_RS07990	COG1741	Belongs to the pirin family
XA10_RS08000	COG3842	ATPase activity
XA10_RS08005	COG1178	ABC-type Fe3 transport system permease component
XA10_RS08010	COG1840	ABC-type Fe3 transport system, periplasmic component
XA10_RS08020	COG0583	DNA-binding transcription factor activity
XA10_RS08030	COG0656	L-ascorbic acid biosynthetic process
XA10_RS08045	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
XA10_RS08050	COG0583	DNA-binding transcription factor activity
XA10_RS08065	COG0783	Belongs to the Dps family
XA10_RS08085	COG0463	Glycosyl transferase, family 2
XA10_RS08105	COG0438	transferase activity, transferring glycosyl groups
XA10_RS08120	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
XA10_RS08145	COG0300	oxidoreductase activity
XA10_RS08190	COG0861	Integral membrane protein TerC family
XA10_RS08195	COG1028	Short-chain dehydrogenase reductase Sdr
XA10_RS08215	COG0714	Associated with various cellular activities
XA10_RS08250	COG3119	arylsulfatase activity
XA10_RS08275	COG2197	response regulator
XA10_RS08285	COG2944	sequence-specific DNA binding
XA10_RS08290	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
XA10_RS08295	COG0625	glutathione transferase activity
XA10_RS08325	COG0179	Fumarylacetoacetate (FAA) hydrolase
XA10_RS08330	COG1028	Short-chain dehydrogenase reductase Sdr
XA10_RS08375	COG0431	NADPH-dependent FMN reductase
XA10_RS08405	COG1028	Short-chain dehydrogenase reductase Sdr
XA10_RS08410	COG0583	DNA-binding transcription factor activity
XA10_RS08425	COG3181	Tripartite tricarboxylate transporter family receptor
XA10_RS08430	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XA10_RS08430	COG2111	Na H antiporter
XA10_RS08435	COG1006	Multisubunit Na H antiporter MnhC subunit
XA10_RS08440	COG0651	ATP synthesis coupled electron transport
XA10_RS08445	COG1863	multisubunit Na H antiporter MnhE subunit
XA10_RS08450	COG2212	antiporter activity
XA10_RS08475	COG0590	tRNA wobble adenosine to inosine editing
XA10_RS08480	COG1619	proteins homologs of microcin C7 resistance protein MccF
XA10_RS08485	COG1024	Enoyl-CoA hydratase
XA10_RS08500	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
XA10_RS08505	COG0488	(ABC) transporter
XA10_RS08545	COG1017	nitric oxide dioxygenase activity
XA10_RS08545	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
XA10_RS08550	COG1959	2 iron, 2 sulfur cluster binding
XA10_RS08555	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XA10_RS08575	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
XA10_RS08580	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
XA10_RS08585	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
XA10_RS08590	COG0084	hydrolase, TatD family'
XA10_RS08605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XA10_RS08615	COG1126	abc transporter atp-binding protein
XA10_RS08620	COG0010	Belongs to the arginase family
XA10_RS08625	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
XA10_RS08630	COG1012	belongs to the aldehyde dehydrogenase family
XA10_RS08640	COG0028	Belongs to the TPP enzyme family
XA10_RS08650	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
XA10_RS08650	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
XA10_RS08660	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XA10_RS08675	COG3189	MarR family transcriptional regulator
XA10_RS08680	COG2010	Cytochrome c
XA10_RS08705	COG4336	lyase activity
XA10_RS08715	COG2205	protein histidine kinase activity
XA10_RS08715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XA10_RS08720	COG2197	response regulator
XA10_RS08725	COG3064	Membrane
XA10_RS08725	COG3210	domain, Protein
XA10_RS08725	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
XA10_RS08735	COG3121	Chaperone
XA10_RS08740	COG3188	usher protein
XA10_RS08745	COG3539	Fimbrial protein
XA10_RS08750	COG2831	hemolysin activation secretion protein
XA10_RS08765	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XA10_RS08790	COG0583	DNA-binding transcription factor activity
XA10_RS08815	COG0668	transmembrane transport
XA10_RS08835	COG0483	inositol monophosphate 1-phosphatase activity
XA10_RS08840	COG1253	flavin adenine dinucleotide binding
XA10_RS08845	COG1968	undecaprenyl-diphosphatase activity
XA10_RS08850	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XA10_RS08865	COG0215	cysteine-tRNA ligase activity
XA10_RS08875	COG0825	malonyl-CoA metabolic process
XA10_RS08885	COG0037	tRNA processing
XA10_RS08890	COG0527	aspartate kinase activity
XA10_RS08915	COG1250	3-hydroxyacyl-CoA dehydrogenase
XA10_RS08920	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
XA10_RS08920	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
XA10_RS08935	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XA10_RS08940	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
XA10_RS08945	COG1028	Short-chain dehydrogenase reductase Sdr
XA10_RS08955	COG0583	DNA-binding transcription factor activity
XA10_RS08985	COG3842	ATPase activity
XA10_RS08995	COG0446	pyridine nucleotide-disulphide oxidoreductase
XA10_RS08995	COG1902	pentaerythritol trinitrate reductase activity
XA10_RS09000	COG1414	Transcriptional regulator
XA10_RS09005	COG1832	CoA-binding protein
XA10_RS09015	COG0251	oxidation-reduction process
XA10_RS09040	COG1902	pentaerythritol trinitrate reductase activity
XA10_RS09050	COG1215	transferase activity, transferring glycosyl groups
XA10_RS09055	COG1649	PFAM Uncharacterised BCR, COG1649
XA10_RS09055	COG0726	polysaccharide deacetylase
XA10_RS09075	COG1846	Transcriptional regulator
XA10_RS09080	COG2197	response regulator
XA10_RS09095	COG0166	Belongs to the GPI family
XA10_RS09100	COG1045	serine acetyltransferase
XA10_RS09110	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
XA10_RS09115	COG0483	inositol monophosphate 1-phosphatase activity
XA10_RS09120	COG1012	belongs to the aldehyde dehydrogenase family
XA10_RS09125	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
XA10_RS09140	COG0210	DNA helicase
XA10_RS09145	COG0598	Magnesium transport protein CorA
XA10_RS09155	COG0747	negative chemotaxis
XA10_RS09160	COG0601	transmembrane transport
XA10_RS09165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XA10_RS09170	COG4172	Belongs to the ABC transporter superfamily
XA10_RS09175	COG1846	Transcriptional regulator
XA10_RS09225	COG4964	Belongs to the GSP D family
XA10_RS09265	COG2204	response regulator
XA10_RS09280	COG1595	DNA-templated transcription, initiation
XA10_RS09290	COG3474	cytochrome
XA10_RS09295	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
XA10_RS09310	COG3384	dioxygenase
XA10_RS09315	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
XA10_RS09340	COG2885	chlorophyll binding
XA10_RS09375	COG0697	spore germination
XA10_RS09380	COG0730	response to heat
XA10_RS09400	COG0583	DNA-binding transcription factor activity
XA10_RS09405	COG0427	acetyl-CoA hydrolase
XA10_RS09460	COG1250	3-hydroxyacyl-CoA dehydrogenase
XA10_RS09465	COG0154	amidase activity
XA10_RS09475	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
XA10_RS09490	COG0495	leucyl-tRNA aminoacylation
XA10_RS09495	COG2814	Major facilitator Superfamily
XA10_RS09525	COG0267	Belongs to the bacterial ribosomal protein bL33 family
XA10_RS09530	COG0227	Belongs to the bacterial ribosomal protein bL28 family
XA10_RS09535	COG2814	Major facilitator Superfamily
XA10_RS09540	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XA10_RS09555	COG4176	ABC-type proline glycine betaine transport system permease component
XA10_RS09565	COG1942	4-Oxalocrotonate Tautomerase
XA10_RS09570	COG0183	Belongs to the thiolase family
XA10_RS09580	COG1802	Transcriptional regulator
XA10_RS09590	COG1024	Enoyl-CoA hydratase
XA10_RS09595	COG0318	PFAM AMP-dependent synthetase and ligase
XA10_RS09600	COG0318	PFAM AMP-dependent synthetase and ligase
XA10_RS09610	COG2032	superoxide dismutase activity
XA10_RS09625	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
XA10_RS09650	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XA10_RS09655	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XA10_RS09665	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
XA10_RS09670	COG0736	holo-[acyl-carrier-protein] synthase activity
XA10_RS09675	COG1472	Belongs to the glycosyl hydrolase 3 family
XA10_RS09680	COG0322	excinuclease ABC activity
XA10_RS09685	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XA10_RS09700	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
XA10_RS09700	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
XA10_RS09705	COG2224	Isocitrate lyase
XA10_RS09725	COG0559	Belongs to the binding-protein-dependent transport system permease family
XA10_RS09735	COG4638	Rieske (2fe-2S)
XA10_RS09745	COG1024	Enoyl-CoA hydratase
XA10_RS09755	COG0633	Ferredoxin
XA10_RS09760	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XA10_RS09775	COG0183	Belongs to the thiolase family
XA10_RS09820	COG2346	COG2346, Truncated hemoglobins
XA10_RS09950	COG2207	Transcriptional regulator
XA10_RS09995	COG1132	(ABC) transporter
XA10_RS10020	COG0659	secondary active sulfate transmembrane transporter activity
XA10_RS10050	COG2169	Transcriptional regulator
XA10_RS10055	COG5507	3-demethylubiquinone-9 3-methyltransferase
XA10_RS10060	COG0384	phenazine biosynthesis protein PhzF
XA10_RS10065	COG0583	DNA-binding transcription factor activity
XA10_RS10070	COG2733	membrane
XA10_RS10085	COG1012	belongs to the aldehyde dehydrogenase family
XA10_RS10090	COG3284	Transcriptional regulator
XA10_RS10110	COG1380	Effector of murein hydrolase LrgA
XA10_RS10115	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
XA10_RS10115	COG4106	trans-aconitate 2-methyltransferase activity
XA10_RS10125	COG0156	8-amino-7-oxononanoate synthase activity
XA10_RS10195	COG1131	(ABC) transporter
XA10_RS10200	COG0842	Transport permease protein
XA10_RS10205	COG0628	permease
XA10_RS10240	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XA10_RS10250	COG0828	Belongs to the bacterial ribosomal protein bS21 family
XA10_RS10255	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
XA10_RS10260	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
XA10_RS10265	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
XA10_RS10270	COG0330	HflC and HflK could
XA10_RS10275	COG0330	HflC and HflK could
XA10_RS10280	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
XA10_RS10285	COG1923	regulation of RNA biosynthetic process
XA10_RS10290	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XA10_RS10295	COG1160	GTP binding
XA10_RS10300	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XA10_RS10305	COG2976	Protein conserved in bacteria
XA10_RS10310	COG0124	histidyl-tRNA synthetase
XA10_RS10315	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
XA10_RS10325	COG0820	rRNA (adenine-C2-)-methyltransferase activity
XA10_RS10330	COG0105	UTP biosynthetic process
XA10_RS10335	COG0525	valine-tRNA ligase activity
XA10_RS10350	COG0642	Histidine kinase
XA10_RS10370	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XA10_RS10375	COG0336	Belongs to the RNA methyltransferase TrmD family
XA10_RS10380	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
XA10_RS10385	COG0228	four-way junction DNA binding
XA10_RS10395	COG0425	Belongs to the sulfur carrier protein TusA family
XA10_RS10400	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
XA10_RS10445	COG0154	amidase activity
XA10_RS10450	COG4172	Belongs to the ABC transporter superfamily
XA10_RS10455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XA10_RS10460	COG0601	transmembrane transport
XA10_RS10465	COG0747	negative chemotaxis
XA10_RS10495	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XA10_RS10505	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
XA10_RS10520	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
XA10_RS10525	COG3395	kinase activity
XA10_RS10540	COG1024	Enoyl-CoA hydratase
XA10_RS10560	COG0633	Ferredoxin
XA10_RS10565	COG0443	Heat shock 70 kDa protein
XA10_RS10570	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
XA10_RS10575	COG0316	Belongs to the HesB IscA family
XA10_RS10580	COG0822	iron-sulfur transferase activity
XA10_RS10585	COG1104	cysteine desulfurase activity
XA10_RS10595	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
XA10_RS10600	COG0556	nucleotide-excision repair
XA10_RS10610	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XA10_RS10615	COG3468	outer membrane autotransporter barrel domain protein
XA10_RS10645	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
XA10_RS10660	COG1960	acyl-CoA dehydrogenase activity
XA10_RS10665	COG1028	Short-chain dehydrogenase reductase Sdr
XA10_RS10670	COG0183	Belongs to the thiolase family
XA10_RS10680	COG1024	Enoyl-CoA hydratase
XA10_RS10695	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XA10_RS10700	COG0583	DNA-binding transcription factor activity
XA10_RS10705	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
XA10_RS10710	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
XA10_RS10715	COG0740	serine-type endopeptidase activity
XA10_RS10720	COG0544	peptidyl-prolyl cis-trans isomerase activity
XA10_RS10740	COG1278	Cold shock
XA10_RS10775	COG2171	N-acyltransferase activity
XA10_RS10780	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XA10_RS10785	COG2890	protein-(glutamine-N5) methyltransferase activity
XA10_RS10790	COG0488	(ABC) transporter
XA10_RS10795	COG4771	TonB-dependent receptor
XA10_RS10800	COG0210	DNA helicase
XA10_RS10820	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
XA10_RS10825	COG0196	riboflavin kinase activity
XA10_RS10830	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
XA10_RS10835	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
XA10_RS10840	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
XA10_RS10850	COG1522	sequence-specific DNA binding
XA10_RS10870	COG2951	lytic endotransglycosylase activity
XA10_RS10875	COG2833	Protein of unknown function (DUF455)
XA10_RS10895	COG0189	ligase activity
XA10_RS10895	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
XA10_RS10900	COG1181	Belongs to the D-alanine--D-alanine ligase family
XA10_RS10900	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
XA10_RS10905	COG3237	CsbD-like
XA10_RS10915	COG2823	Periplasmic or secreted lipoprotein
XA10_RS10930	COG4181	ATPase activity
XA10_RS10940	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XA10_RS10945	COG0584	glycerophosphoryl diester phosphodiesterase
XA10_RS10950	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
XA10_RS10960	COG0678	peroxiredoxin activity
XA10_RS10960	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
XA10_RS10970	COG0789	Transcriptional regulator
XA10_RS10975	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
XA10_RS11005	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
XA10_RS11010	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
XA10_RS11020	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
XA10_RS11025	COG2252	PERMEase
XA10_RS11035	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XA10_RS11065	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
XA10_RS11070	COG2358	TRAP transporter, solute receptor (TAXI family
XA10_RS11100	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XA10_RS11105	COG1366	Belongs to the anti-sigma-factor antagonist family
XA10_RS11110	COG2172	sigma factor antagonist activity
XA10_RS11115	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
XA10_RS11125	COG2770	Histidine kinase
XA10_RS11125	COG2208	phosphoserine phosphatase activity
XA10_RS11150	COG1595	DNA-templated transcription, initiation
XA10_RS11165	COG4792	protein secretion
XA10_RS11170	COG4791	protein targeting
XA10_RS11175	COG4794	Type iii secretion
XA10_RS11180	COG4790	Type iii secretion
XA10_RS11215	COG4669	(LipO)protein
XA10_RS11280	COG4789	Type iii secretion
XA10_RS11310	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XA10_RS11315	COG0840	transmembrane signaling receptor activity
XA10_RS11320	COG2233	PERMEase
XA10_RS11345	COG0492	ferredoxin-NADP+ reductase activity
XA10_RS11350	COG1840	ABC-type Fe3 transport system, periplasmic component
XA10_RS11355	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XA10_RS11360	COG1178	ABC-type Fe3 transport system permease component
XA10_RS11365	COG3842	ATPase activity
XA10_RS11370	COG0583	DNA-binding transcription factor activity
XA10_RS11390	COG0501	Belongs to the peptidase M48B family
XA10_RS11400	COG0697	spore germination
XA10_RS11410	COG1846	Transcriptional regulator
XA10_RS11420	COG1566	PFAM secretion protein HlyD family protein
XA10_RS11425	COG2814	Major facilitator Superfamily
XA10_RS11430	COG0473	3-isopropylmalate dehydrogenase activity
XA10_RS11440	COG0747	negative chemotaxis
XA10_RS11450	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XA10_RS11465	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
XA10_RS11490	COG1012	belongs to the aldehyde dehydrogenase family
XA10_RS11500	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
XA10_RS11505	COG1115	amino acid carrier protein
XA10_RS11510	COG0433	COG0433 Predicted ATPase
XA10_RS11515	COG0217	transcriptional regulatory protein
XA10_RS11520	COG0151	Belongs to the GarS family
XA10_RS11525	COG0408	coproporphyrinogen oxidase activity
XA10_RS11530	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
XA10_RS11535	COG0799	negative regulation of ribosome biogenesis
XA10_RS11540	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
XA10_RS11545	COG0424	maF-like protein
XA10_RS11550	COG3468	outer membrane autotransporter barrel domain protein
XA10_RS11590	COG1530	ribonuclease E activity
XA10_RS11595	COG0077	Prephenate dehydratase
XA10_RS11610	COG1132	(ABC) transporter
XA10_RS11615	COG0859	PFAM glycosyl transferase family 9
XA10_RS11640	COG2194	sulfuric ester hydrolase activity
XA10_RS11645	COG0438	transferase activity, transferring glycosyl groups
XA10_RS11650	COG0463	Glycosyl transferase, family 2
XA10_RS11655	COG0726	polysaccharide deacetylase
XA10_RS11660	COG0438	transferase activity, transferring glycosyl groups
XA10_RS11675	COG1643	Atp-dependent helicase
XA10_RS11680	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
XA10_RS11680	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
XA10_RS11685	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
XA10_RS11695	COG0704	Plays a role in the regulation of phosphate uptake
XA10_RS11700	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
XA10_RS11705	COG1960	acyl-CoA dehydrogenase activity
XA10_RS11730	COG1177	transmembrane transport
XA10_RS11735	COG1176	ABC-type spermidine putrescine transport system, permease component I
XA10_RS11740	COG3842	ATPase activity
XA10_RS11745	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
XA10_RS11760	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
XA10_RS11765	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XA10_RS11775	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
XA10_RS11775	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
XA10_RS11795	COG0372	Belongs to the citrate synthase family
XA10_RS11800	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
XA10_RS11805	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
XA10_RS11810	COG1053	succinate dehydrogenase
XA10_RS11815	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
XA10_RS11820	COG2009	succinate dehydrogenase
XA10_RS11825	COG2188	Transcriptional regulator
XA10_RS11830	COG0039	L-malate dehydrogenase activity
XA10_RS11860	COG1981	membrane
XA10_RS11885	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
XA10_RS11895	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
XA10_RS11925	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
XA10_RS11930	COG0148	phosphopyruvate hydratase activity
XA10_RS11940	COG2877	3-deoxy-8-phosphooctulonate synthase activity
XA10_RS11945	COG0504	CTP synthase activity
XA10_RS11970	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XA10_RS11980	COG0747	negative chemotaxis
XA10_RS11985	COG4172	Belongs to the ABC transporter superfamily
XA10_RS11990	COG1446	asparaginase
XA10_RS12020	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
XA10_RS12035	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
XA10_RS12040	COG0697	spore germination
XA10_RS12045	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
XA10_RS12055	COG3193	protein, possibly involved in utilization of glycolate and propanediol
XA10_RS12060	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
XA10_RS12065	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
XA10_RS12070	COG0791	NLP P60 protein
XA10_RS12085	COG0583	DNA-binding transcription factor activity
XA10_RS12100	COG0583	DNA-binding transcription factor activity
XA10_RS12110	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XA10_RS12125	COG0670	Belongs to the BI1 family
XA10_RS12130	COG3181	Tripartite tricarboxylate transporter family receptor
XA10_RS12140	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
XA10_RS12150	COG1381	Involved in DNA repair and RecF pathway recombination
XA10_RS12155	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
XA10_RS12160	COG0571	ribonuclease III activity
XA10_RS12165	COG0681	Belongs to the peptidase S26 family
XA10_RS12170	COG0481	GTPase activity
XA10_RS12175	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XA10_RS12200	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XA10_RS12205	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XA10_RS12220	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XA10_RS12225	COG0416	fatty acid biosynthetic process
XA10_RS12230	COG0333	Belongs to the bacterial ribosomal protein bL32 family
XA10_RS12235	COG1399	metal-binding, possibly nucleic acid-binding protein
XA10_RS12240	COG0424	maF-like protein
XA10_RS12250	COG3023	N-Acetylmuramoyl-L-alanine amidase
XA10_RS12255	COG1289	transmembrane transporter activity
XA10_RS12265	COG3022	response to hydroperoxide
XA10_RS12280	COG0135	phosphoribosylanthranilate isomerase activity
XA10_RS12295	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
XA10_RS12300	COG0101	tRNA pseudouridine synthase activity
XA10_RS12310	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
XA10_RS12315	COG0473	3-isopropylmalate dehydrogenase activity
XA10_RS12320	COG0066	3-isopropylmalate dehydratase activity
XA10_RS12325	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
XA10_RS12335	COG1122	ATPase activity
XA10_RS12365	COG0437	4 iron, 4 sulfur cluster binding
XA10_RS12370	COG3383	formate dehydrogenase (NAD+) activity
XA10_RS12370	COG0243	molybdopterin cofactor binding
XA10_RS12400	COG0489	protein tyrosine kinase activity
XA10_RS12405	COG0746	molybdenum cofactor guanylyltransferase activity
XA10_RS12410	COG0303	'Molybdopterin
XA10_RS12415	COG1763	Mo-molybdopterin cofactor biosynthetic process
XA10_RS12425	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
XA10_RS12430	COG5001	Diguanylate cyclase
XA10_RS12450	COG3842	ATPase activity
XA10_RS12460	COG0406	alpha-ribazole phosphatase activity
XA10_RS12470	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
XA10_RS12475	COG0505	Belongs to the CarA family
XA10_RS12480	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
XA10_RS12510	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
XA10_RS12515	COG1960	acyl-CoA dehydrogenase activity
XA10_RS12525	COG2867	negative regulation of translational initiation
XA10_RS12535	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
XA10_RS12540	COG3706	GGDEF domain
XA10_RS12545	COG0330	HflC and HflK could
XA10_RS12560	COG0519	Catalyzes the synthesis of GMP from XMP
XA10_RS12560	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XA10_RS12570	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
XA10_RS12575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XA10_RS12580	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
XA10_RS12585	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XA10_RS12595	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XA10_RS12600	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XA10_RS12605	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
XA10_RS12610	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XA10_RS12615	COG0750	zinc metalloprotease
XA10_RS12620	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
XA10_RS12630	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
XA10_RS12635	COG0233	cytoplasmic translational termination
XA10_RS12640	COG0528	UMP kinase activity
XA10_RS12645	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
XA10_RS12650	COG0052	Belongs to the universal ribosomal protein uS2 family
XA10_RS12655	COG0024	Methionine aminopeptidase
XA10_RS12660	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
XA10_RS12690	COG0285	dihydrofolate synthase activity
XA10_RS12725	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
XA10_RS12735	COG1677	Flagellar hook-basal body complex protein FliE
XA10_RS12745	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
XA10_RS12755	COG1157	protein secretion by the type III secretion system
XA10_RS12780	COG1580	Controls the rotational direction of flagella during chemotaxis
XA10_RS12800	COG1338	Plays a role in the flagellum-specific transport system
XA10_RS12820	COG0840	transmembrane signaling receptor activity
XA10_RS12825	COG0840	transmembrane signaling receptor activity
XA10_RS12830	COG0840	transmembrane signaling receptor activity
XA10_RS12840	COG1256	bacterial-type flagellum assembly
XA10_RS12850	COG1706	bacterial-type flagellum-dependent cell motility
XA10_RS12855	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
XA10_RS12870	COG1749	Flagellar hook protein flgE
XA10_RS12880	COG1558	bacterial-type flagellum-dependent cell motility
XA10_RS12885	COG1815	bacterial-type flagellum-dependent cell motility
XA10_RS12925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XA10_RS12930	COG0765	amino acid transport
XA10_RS12935	COG1126	abc transporter atp-binding protein
XA10_RS12950	COG4948	Mandelate Racemase Muconate Lactonizing
XA10_RS12955	COG3181	Tripartite tricarboxylate transporter family receptor
XA10_RS12965	COG0066	3-isopropylmalate dehydratase activity
XA10_RS12980	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XA10_RS12990	COG3181	Tripartite tricarboxylate transporter family receptor
XA10_RS13000	COG1802	Transcriptional regulator
XA10_RS13015	COG0583	DNA-binding transcription factor activity
XA10_RS13035	COG1695	Transcriptional regulator
XA10_RS13045	COG3568	Endonuclease Exonuclease Phosphatase
XA10_RS13050	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XA10_RS13065	COG0392	lysyltransferase activity
XA10_RS13105	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XA10_RS13115	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XA10_RS13135	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
XA10_RS13165	COG0667	Aldo Keto reductase
XA10_RS13180	COG2259	Doxx family
XA10_RS13210	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XA10_RS13230	COG0386	Belongs to the glutathione peroxidase family
XA10_RS13235	COG0625	glutathione transferase activity
XA10_RS13260	COG0688	phosphatidylethanolamine metabolic process
XA10_RS13270	COG1464	Belongs to the NlpA lipoprotein family
XA10_RS13285	COG2363	Small membrane protein
XA10_RS13310	COG3842	ATPase activity
XA10_RS13315	COG0395	ABC-type sugar transport system, permease component
XA10_RS13320	COG1175	transmembrane transport
XA10_RS13325	COG1653	transport
XA10_RS13335	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XA10_RS13350	COG0559	Belongs to the binding-protein-dependent transport system permease family
XA10_RS13370	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
XA10_RS13385	COG0697	spore germination
XA10_RS13395	COG2311	Membrane
XA10_RS13420	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
XA10_RS13430	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
XA10_RS13435	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XA10_RS13440	COG1760	l-serine dehydratase
XA10_RS13445	COG1283	sodium-dependent phosphate transmembrane transporter activity
XA10_RS13450	COG0412	Dienelactone hydrolase
XA10_RS13465	COG1611	Belongs to the LOG family
XA10_RS13485	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
XA10_RS13490	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
XA10_RS13495	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
XA10_RS13500	COG0195	Participates in both transcription termination and antitermination
XA10_RS13500	COG2251	uridine kinase activity
XA10_RS13505	COG0779	Required for maturation of 30S ribosomal subunits
XA10_RS13510	COG1187	pseudouridine synthase activity
XA10_RS13515	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
XA10_RS13525	COG0583	DNA-binding transcription factor activity
XA10_RS13535	COG0523	cobalamin synthesis protein
XA10_RS13555	COG0625	glutathione transferase activity
XA10_RS13560	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
XA10_RS13565	COG1047	Peptidyl-prolyl cis-trans
XA10_RS13570	COG2003	Belongs to the UPF0758 family
XA10_RS13575	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
XA10_RS13580	COG3483	tryptophan 2,3-dioxygenase activity
XA10_RS13585	COG0254	rRNA binding
XA10_RS13595	COG0534	Mate efflux family protein
XA10_RS13615	COG2304	oxidoreductase activity
XA10_RS13635	COG1028	Short-chain dehydrogenase reductase Sdr
XA10_RS13640	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
XA10_RS13645	COG1562	ergosterol biosynthetic process
XA10_RS13650	COG1562	ergosterol biosynthetic process
XA10_RS13655	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
XA10_RS13655	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
XA10_RS13660	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
XA10_RS13670	COG0842	Transport permease protein
XA10_RS13675	COG1131	(ABC) transporter
XA10_RS13695	COG1477	protein flavinylation
XA10_RS13710	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
XA10_RS13725	COG5564	TIM-barrel signal transduction protein
XA10_RS13730	COG5441	Belongs to the UPF0261 family
XA10_RS13740	COG3468	outer membrane autotransporter barrel domain protein
XA10_RS13745	COG3468	outer membrane autotransporter barrel domain protein
XA10_RS13760	COG0542	response to heat
XA10_RS13765	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XA10_RS13780	COG0494	nUDIX hydrolase
XA10_RS13785	COG3530	Putative quorum-sensing-regulated virulence factor
XA10_RS13795	COG1595	DNA-templated transcription, initiation
XA10_RS13800	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XA10_RS13835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XA10_RS13840	COG0765	amino acid transport
XA10_RS13845	COG0765	amino acid transport
XA10_RS13870	COG2988	succinylglutamate desuccinylase activity
XA10_RS13895	COG3181	Tripartite tricarboxylate transporter family receptor
XA10_RS13900	COG2084	Dehydrogenase
XA10_RS13915	COG1619	proteins homologs of microcin C7 resistance protein MccF
XA10_RS13930	COG2814	Major facilitator Superfamily
XA10_RS13940	COG0583	DNA-binding transcription factor activity
XA10_RS13980	COG0672	)-iron permease
XA10_RS13995	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
XA10_RS14000	COG1028	Short-chain dehydrogenase reductase Sdr
XA10_RS14005	COG3243	poly(R)-hydroxyalkanoic acid synthase
XA10_RS14015	COG0564	pseudouridine synthase activity
XA10_RS14025	COG1199	ATP-dependent helicase activity
XA10_RS14030	COG2183	response to ionizing radiation
XA10_RS14035	COG0180	Tryptophanyl-tRNA synthetase
XA10_RS14060	COG3181	Tripartite tricarboxylate transporter family receptor
XA10_RS14070	COG0583	DNA-binding transcription factor activity
XA10_RS14075	COG1028	Short-chain dehydrogenase reductase Sdr
XA10_RS14080	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
XA10_RS14085	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XA10_RS14090	COG0508	dehydrogenase complex catalyzes the overall conversion of
XA10_RS14095	COG0567	Dehydrogenase, E1 component
XA10_RS14105	COG1522	sequence-specific DNA binding
XA10_RS14115	COG0281	malic enzyme
XA10_RS14115	COG0280	phosphate acetyltransferase
XA10_RS14120	COG3539	Fimbrial protein
XA10_RS14135	COG0613	PHP domain protein
XA10_RS14145	COG2333	competence protein COMEC
XA10_RS14145	COG0658	competence protein
XA10_RS14175	COG0084	hydrolase, TatD family'
XA10_RS14180	COG1136	(ABC) transporter
XA10_RS14195	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
XA10_RS14205	COG1028	Short-chain dehydrogenase reductase Sdr
XA10_RS14210	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
XA10_RS14225	COG1022	Amp-dependent synthetase and ligase
XA10_RS14260	COG2205	protein histidine kinase activity
XA10_RS14265	COG0745	RESPONSE REGULATOR receiver
XA10_RS14270	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
XA10_RS14280	COG1295	ribonuclease BN
XA10_RS14295	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XA10_RS14325	COG1534	Rna-binding protein
XA10_RS14330	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
XA10_RS14335	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
XA10_RS14345	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XA10_RS14355	COG0248	Ppx GppA phosphatase
XA10_RS14380	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
XA10_RS14395	COG2732	(Barnase) inhibitor
XA10_RS14405	COG0281	malic enzyme
XA10_RS14405	COG0280	phosphate acetyltransferase
XA10_RS14415	COG0436	Aminotransferase
XA10_RS14420	COG0741	lytic transglycosylase activity
XA10_RS14425	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
XA10_RS14450	COG1648	precorrin-2 dehydrogenase activity
XA10_RS14450	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XA10_RS14455	COG3468	outer membrane autotransporter barrel domain protein
XA10_RS14465	COG3468	outer membrane autotransporter barrel domain protein
XA10_RS14475	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
XA10_RS14480	COG2027	D-alanyl-D-alanine carboxypeptidase
XA10_RS14485	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
XA10_RS14490	COG0343	queuine tRNA-ribosyltransferase activity
XA10_RS14495	COG1862	Preprotein translocase
XA10_RS14500	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XA10_RS14505	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XA10_RS14520	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XA10_RS14525	COG1702	phosphate starvation-inducible protein PhoH
XA10_RS14530	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
XA10_RS14535	COG4535	Mg2 and Co2 transporter CorC
XA10_RS14545	COG0667	Aldo Keto reductase
XA10_RS14570	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
XA10_RS14575	COG0745	RESPONSE REGULATOR receiver
XA10_RS14580	COG2201	protein-glutamate methylesterase activity
XA10_RS14590	COG0840	transmembrane signaling receptor activity
XA10_RS14605	COG0745	RESPONSE REGULATOR receiver
XA10_RS14640	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
XA10_RS14650	COG0739	heme binding
XA10_RS14660	COG0521	Mo-molybdopterin cofactor biosynthetic process
XA10_RS14670	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
XA10_RS14705	COG0625	glutathione transferase activity
XA10_RS14720	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
XA10_RS14725	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
XA10_RS14730	COG0126	phosphoglycerate kinase activity
XA10_RS14735	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
XA10_RS14740	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
XA10_RS14745	COG1385	rRNA (uridine-N3-)-methyltransferase activity
XA10_RS14760	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
XA10_RS14765	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XA10_RS14770	COG0508	dehydrogenase complex catalyzes the overall conversion of
XA10_RS14775	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
XA10_RS14785	COG4566	intracellular signal transduction
XA10_RS14790	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
XA10_RS14795	COG0339	signal peptide processing
XA10_RS14800	COG1999	signal sequence binding
XA10_RS14820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XA10_RS14830	COG1187	pseudouridine synthase activity
XA10_RS14835	COG3161	chorismate lyase activity
XA10_RS14840	COG2814	Major facilitator Superfamily
XA10_RS14850	COG0667	Aldo Keto reductase
XA10_RS14865	COG0335	large ribosomal subunit rRNA binding
XA10_RS14895	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
XA10_RS14900	COG4208	sulfate ABC transporter
XA10_RS14905	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
XA10_RS14920	COG0450	alkyl hydroperoxide reductase
XA10_RS14925	COG1960	acyl-CoA dehydrogenase activity
XA10_RS14940	COG0123	including yeast histone deacetylase and acetoin utilization protein
XA10_RS14945	COG2951	lytic endotransglycosylase activity
XA10_RS14960	COG1596	polysaccharide export
XA10_RS14960	COG1555	photosystem II stabilization
XA10_RS14965	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XA10_RS14970	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
XA10_RS14975	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
XA10_RS14995	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
XA10_RS15000	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
XA10_RS15005	COG0287	Prephenate dehydrogenase
XA10_RS15015	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
XA10_RS15030	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XA10_RS15040	COG2814	Major facilitator Superfamily
XA10_RS15065	COG0583	DNA-binding transcription factor activity
XA10_RS15105	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
XA10_RS15120	COG0667	Aldo Keto reductase
XA10_RS15130	COG5265	(ABC) transporter
XA10_RS15175	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XA10_RS15180	COG0439	Biotin carboxylase
XA10_RS15185	COG2188	Transcriptional regulator
XA10_RS15210	COG0511	ligase activity, forming carbon-carbon bonds
XA10_RS15220	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
XA10_RS15240	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
XA10_RS15260	COG0500	methyltransferase
XA10_RS15265	COG5265	(ABC) transporter
XA10_RS15280	COG0028	Belongs to the TPP enzyme family
XA10_RS15285	COG0440	acetolactate synthase activity
XA10_RS15290	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
XA10_RS15295	COG1183	phosphatidylcholine synthase activity
XA10_RS15310	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
XA10_RS15315	COG1185	polyribonucleotide nucleotidyltransferase activity
XA10_RS15330	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
XA10_RS15350	COG0149	triose-phosphate isomerase activity
XA10_RS15355	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
XA10_RS15365	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
XA10_RS15375	COG3799	methylaspartate ammonia-lyase activity
XA10_RS15410	COG0583	DNA-binding transcription factor activity
XA10_RS15415	COG0626	cystathionine gamma-synthase activity
XA10_RS15420	COG3608	succinylglutamate desuccinylase aspartoacylase
XA10_RS15440	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XA10_RS15460	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
XA10_RS15475	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XA10_RS15480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XA10_RS15485	COG1733	regulation of RNA biosynthetic process
XA10_RS15495	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
XA10_RS15500	COG0583	DNA-binding transcription factor activity
XA10_RS15505	COG1597	lipid kinase activity
XA10_RS15515	COG0671	phosphoesterase, PA-phosphatase related
XA10_RS15545	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
XA10_RS15550	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XA10_RS15555	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XA10_RS15560	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XA10_RS15565	COG0649	NAD binding
XA10_RS15570	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
XA10_RS15580	COG1034	ATP synthesis coupled electron transport
XA10_RS15585	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
XA10_RS15590	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XA10_RS15600	COG0713	ATP synthesis coupled electron transport
XA10_RS15615	COG1007	ATP synthesis coupled electron transport
XA10_RS15625	COG4774	siderophore transport
XA10_RS15630	COG4774	siderophore transport
XA10_RS15645	COG0028	Belongs to the TPP enzyme family
XA10_RS15650	COG3181	Tripartite tricarboxylate transporter family receptor
XA10_RS15655	COG0583	DNA-binding transcription factor activity
XA10_RS15660	COG0560	Phosphoserine phosphatase
XA10_RS15665	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
XA10_RS15670	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
XA10_RS15675	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
XA10_RS15685	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
XA10_RS15690	COG0308	aminopeptidase N
XA10_RS15710	COG0028	Belongs to the TPP enzyme family
XA10_RS15730	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XA10_RS15740	COG0318	PFAM AMP-dependent synthetase and ligase
XA10_RS15750	COG1802	Transcriptional regulator
XA10_RS15760	COG1802	Transcriptional regulator
XA10_RS15770	COG1028	Short-chain dehydrogenase reductase Sdr
XA10_RS15790	COG1126	abc transporter atp-binding protein
XA10_RS15795	COG0765	amino acid transport
XA10_RS15800	COG0765	amino acid transport
XA10_RS15815	COG1538	Outer membrane efflux protein
XA10_RS15820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XA10_RS15825	COG2274	protein secretion by the type I secretion system
XA10_RS15830	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
XA10_RS15840	COG2994	toxin metabolic process
XA10_RS15855	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XA10_RS15860	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
XA10_RS15870	COG0583	DNA-binding transcription factor activity
XA10_RS15880	COG0142	geranyltranstransferase activity
XA10_RS15890	COG0261	This protein binds to 23S rRNA in the presence of protein L20
XA10_RS15895	COG0211	Belongs to the bacterial ribosomal protein bL27 family
XA10_RS15900	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
XA10_RS15905	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
XA10_RS15950	COG3712	iron ion homeostasis
XA10_RS15955	COG4774	siderophore transport
XA10_RS15960	COG2353	YceI-like domain
XA10_RS15975	COG0019	diaminopimelate decarboxylase activity
XA10_RS15995	COG0747	negative chemotaxis
XA10_RS16000	COG0601	transmembrane transport
XA10_RS16005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XA10_RS16015	COG0154	amidase activity
XA10_RS16020	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
XA10_RS16045	COG2154	pterin-4-alpha-carbinolamine dehydratase
XA10_RS16055	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
XA10_RS16065	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
XA10_RS16070	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XA10_RS16075	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
XA10_RS16080	COG1929	Belongs to the glycerate kinase type-1 family
XA10_RS16085	COG0469	pyruvate kinase activity
XA10_RS16090	COG0700	Nucleoside recognition
XA10_RS16125	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
XA10_RS16130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XA10_RS16145	COG0823	Involved in the tonB-independent uptake of proteins
XA10_RS16155	COG0848	biopolymer transport protein
XA10_RS16160	COG0811	peptide transport
XA10_RS16165	COG0824	Thioesterase
XA10_RS16170	COG0442	prolyl-tRNA aminoacylation
XA10_RS16175	COG0494	nUDIX hydrolase
XA10_RS16190	COG2135	peptidase activity
XA10_RS16260	COG1196	nuclear chromosome segregation
XA10_RS16405	COG1464	Belongs to the NlpA lipoprotein family
XA10_RS16435	COG4211	Belongs to the binding-protein-dependent transport system permease family
XA10_RS16445	COG0154	amidase activity
XA10_RS16450	COG0288	reversible hydration of carbon dioxide
XA10_RS16465	COG0514	ATP-dependent DNA helicase (RecQ)
XA10_RS16470	COG2255	four-way junction helicase activity
XA10_RS16485	COG0632	four-way junction helicase activity
XA10_RS16490	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
XA10_RS16510	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XA10_RS16520	COG0006	proline dipeptidase activity
XA10_RS16545	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
XA10_RS16560	COG4783	chaperone-mediated protein folding
XA10_RS16565	COG0429	hydrolase of the alpha beta-hydrolase fold
XA10_RS16595	COG0513	Belongs to the DEAD box helicase family
XA10_RS16615	COG1546	Belongs to the CinA family
XA10_RS16615	COG1058	Belongs to the CinA family
XA10_RS16620	COG1414	Transcriptional regulator
XA10_RS16640	COG0167	dihydroorotate dehydrogenase activity
XA10_RS16645	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
XA10_RS16650	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
XA10_RS16660	COG0583	DNA-binding transcription factor activity
XA10_RS16720	COG0280	phosphate acetyltransferase
XA10_RS16720	COG0281	malic enzyme
XA10_RS16730	COG0601	transmembrane transport
XA10_RS16735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XA10_RS16740	COG4172	Belongs to the ABC transporter superfamily
XA10_RS16770	COG0640	Transcriptional regulator
XA10_RS16785	COG3135	benzoate transporter
XA10_RS16790	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
XA10_RS16795	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
XA10_RS16800	COG0742	ribosomal rna small subunit methyltransferase
XA10_RS16815	COG3639	organic phosphonate transmembrane transporter activity
XA10_RS16820	COG3639	organic phosphonate transmembrane transporter activity
XA10_RS16825	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
XA10_RS16860	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
XA10_RS16865	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XA10_RS16875	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
XA10_RS16880	COG1058	Belongs to the CinA family
XA10_RS16880	COG1546	Belongs to the CinA family
XA10_RS16885	COG0284	orotidine-5'-phosphate decarboxylase activity
XA10_RS16890	COG1252	NADH dehydrogenase
XA10_RS16905	COG3468	outer membrane autotransporter barrel domain protein
XA10_RS16910	COG0459	protein refolding
XA10_RS16915	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
XA10_RS16935	COG1053	succinate dehydrogenase
XA10_RS16945	COG0583	DNA-binding transcription factor activity
XA10_RS16950	COG1053	succinate dehydrogenase
XA10_RS16970	COG3706	GGDEF domain
XA10_RS17005	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XA10_RS17010	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
XA10_RS17020	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XA10_RS17030	COG0069	glutamate synthase activity
XA10_RS17035	COG2391	methyltransferase activity
XA10_RS17040	COG0679	Auxin Efflux Carrier
XA10_RS17065	COG0557	exoribonuclease II activity
XA10_RS17070	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XA10_RS17080	COG3128	pkhd-type hydroxylase
XA10_RS17085	COG0776	regulation of translation
XA10_RS17115	COG0642	Histidine kinase
XA10_RS17120	COG3158	transport of potassium into the cell
XA10_RS17125	COG0137	argininosuccinate synthase activity
XA10_RS17130	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
XA10_RS17135	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
XA10_RS17145	COG0583	DNA-binding transcription factor activity
XA10_RS17155	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XA10_RS17175	COG2186	Transcriptional regulator
XA10_RS17185	COG2223	nitrite transmembrane transporter activity
XA10_RS17195	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XA10_RS17200	COG0450	alkyl hydroperoxide reductase
XA10_RS17220	COG1214	PFAM Peptidase M22, glycoprotease
XA10_RS17225	COG1573	uracil-dna glycosylase
XA10_RS17230	COG0477	Major facilitator Superfamily
XA10_RS17235	COG1196	nuclear chromosome segregation
XA10_RS17245	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
XA10_RS17250	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XA10_RS17265	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
XA10_RS17270	COG1122	ATPase activity
XA10_RS17275	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
XA10_RS17280	COG1268	BioY protein
XA10_RS17300	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XA10_RS17335	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
XA10_RS17340	COG2878	Part of a membrane complex involved in electron transport
XA10_RS17355	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
XA10_RS17360	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
XA10_RS17365	COG0251	oxidation-reduction process
XA10_RS17375	COG3228	Belongs to the MtfA family
XA10_RS17380	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XA10_RS17390	COG0133	tryptophan synthase activity
XA10_RS17395	COG0159	tryptophan synthase activity
XA10_RS17400	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
XA10_RS17405	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
XA10_RS17420	COG1530	ribonuclease E activity
XA10_RS17430	COG0546	phosphoglycolate phosphatase activity
XA10_RS17435	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
XA10_RS17440	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
XA10_RS17450	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XA10_RS17455	COG0583	DNA-binding transcription factor activity
XA10_RS17465	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XA10_RS17485	COG0251	oxidation-reduction process
XA10_RS17490	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
XA10_RS17490	COG1017	nitric oxide dioxygenase activity
XA10_RS17495	COG2031	fatty acid transporter
XA10_RS17500	COG1012	belongs to the aldehyde dehydrogenase family
XA10_RS17505	COG1802	Transcriptional regulator
XA10_RS17515	COG1278	Cold shock
XA10_RS17520	COG0583	DNA-binding transcription factor activity
XA10_RS17540	COG0183	Belongs to the thiolase family
XA10_RS17550	COG1960	acyl-CoA dehydrogenase activity
XA10_RS17555	COG0583	DNA-binding transcription factor activity
XA10_RS17560	COG3181	Tripartite tricarboxylate transporter family receptor
XA10_RS17565	COG1024	Enoyl-CoA hydratase
XA10_RS17570	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XA10_RS17575	COG1253	flavin adenine dinucleotide binding
XA10_RS17580	COG1285	pathogenesis
XA10_RS17590	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XA10_RS17605	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
XA10_RS17615	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XA10_RS17620	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XA10_RS17635	COG2031	fatty acid transporter
XA10_RS17645	COG0786	glutamate:sodium symporter activity
XA10_RS17665	COG0463	Glycosyl transferase, family 2
XA10_RS17670	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
XA10_RS17700	COG0697	spore germination
XA10_RS17710	COG3181	Tripartite tricarboxylate transporter family receptor
XA10_RS17735	COG0028	Belongs to the TPP enzyme family
XA10_RS17740	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XA10_RS17745	COG1024	Enoyl-CoA hydratase
XA10_RS17745	COG1250	3-hydroxyacyl-CoA dehydrogenase
XA10_RS17750	COG3181	Tripartite tricarboxylate transporter family receptor
XA10_RS17760	COG0492	ferredoxin-NADP+ reductase activity
XA10_RS17780	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XA10_RS17790	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XA10_RS17810	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
XA10_RS17825	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
XA10_RS17830	COG2823	Periplasmic or secreted lipoprotein
XA10_RS17845	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
XA10_RS17855	COG1309	transcriptional regulator
XA10_RS17860	COG0471	metal ion transport
XA10_RS17865	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
XA10_RS17870	COG0772	Belongs to the SEDS family
XA10_RS17875	COG0768	penicillin binding
XA10_RS17885	COG1792	Involved in formation and maintenance of cell shape
XA10_RS17890	COG1077	Cell shape determining protein MreB Mrl
XA10_RS17895	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
XA10_RS17900	COG0154	amidase activity
XA10_RS17905	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
XA10_RS17910	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
XA10_RS17915	COG0708	Exodeoxyribonuclease III
XA10_RS17920	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
XA10_RS17925	COG2860	membrane
XA10_RS17960	COG1012	belongs to the aldehyde dehydrogenase family
XA10_RS17970	COG3069	C4-dicarboxylate transmembrane transporter activity
XA10_RS17980	COG1802	Transcriptional regulator
XA10_RS18015	COG1595	DNA-templated transcription, initiation
XA10_RS18020	COG3712	iron ion homeostasis
XA10_RS18030	COG3720	iron ion transport
XA10_RS18035	COG4558	Periplasmic binding protein
XA10_RS18040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XA10_RS18045	COG1120	ATPase activity
XA10_RS18050	COG1683	Conserved Protein
XA10_RS18080	COG3064	Membrane
XA10_RS18100	COG1234	tRNA 3'-trailer cleavage
XA10_RS18135	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XA10_RS18145	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
XA10_RS18160	COG0540	Belongs to the ATCase OTCase family
XA10_RS18165	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
XA10_RS18170	COG1678	Uncharacterized ACR, COG1678
XA10_RS18185	COG0352	thiamine-phosphate diphosphorylase activity
XA10_RS18190	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XA10_RS18215	COG1960	acyl-CoA dehydrogenase activity
XA10_RS18220	COG1024	Enoyl-CoA hydratase
XA10_RS18290	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
XA10_RS18300	COG0583	DNA-binding transcription factor activity
XA10_RS18305	COG2814	Major facilitator Superfamily
XA10_RS18310	COG0129	dihydroxy-acid dehydratase activity
XA10_RS18315	COG2207	Transcriptional regulator
XA10_RS18320	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
XA10_RS18330	COG0657	acetylesterase activity
XA10_RS18335	COG0747	negative chemotaxis
XA10_RS18340	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XA10_RS18345	COG2808	Putative FMN-binding domain
XA10_RS18360	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
XA10_RS18365	COG1970	mechanosensitive ion channel activity
XA10_RS18370	COG0723	plastoquinol--plastocyanin reductase activity
XA10_RS18375	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
XA10_RS18380	COG2857	Cytochrome c1
XA10_RS18385	COG0625	glutathione transferase activity
XA10_RS18390	COG2969	positive regulation of protein catabolic process
XA10_RS18420	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
XA10_RS18435	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
XA10_RS18440	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
XA10_RS18445	COG4988	ABC transporter
XA10_RS18455	COG1294	oxidase, subunit
XA10_RS18480	COG1960	acyl-CoA dehydrogenase activity
XA10_RS18490	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XA10_RS18495	COG0405	Gamma-glutamyltransferase
XA10_RS18505	COG3181	Tripartite tricarboxylate transporter family receptor
XA10_RS18515	COG0114	fumarate hydratase activity
XA10_RS18520	COG0802	atpase or kinase
XA10_RS18525	COG0860	N-Acetylmuramoyl-L-alanine amidase
XA10_RS18530	COG0586	Pfam SNARE associated Golgi protein
XA10_RS18535	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
XA10_RS18540	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
XA10_RS18545	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
XA10_RS18560	COG0617	tRNA 3'-terminal CCA addition
XA10_RS18585	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
XA10_RS18590	COG2188	Transcriptional regulator
XA10_RS18600	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XA10_RS18610	COG1028	Short-chain dehydrogenase reductase Sdr
XA10_RS18635	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XA10_RS18640	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
XA10_RS18645	COG1012	belongs to the aldehyde dehydrogenase family
XA10_RS18665	COG4257	antibiotic catabolic process
XA10_RS18675	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
XA10_RS18680	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
XA10_RS18690	COG1250	3-hydroxyacyl-CoA dehydrogenase
XA10_RS18695	COG2031	fatty acid transporter
XA10_RS18700	COG1028	Short-chain dehydrogenase reductase Sdr
XA10_RS18705	COG1414	Transcriptional regulator
XA10_RS18715	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
XA10_RS18730	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XA10_RS18770	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XA10_RS18770	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XA10_RS18775	COG0509	glycine decarboxylation via glycine cleavage system
XA10_RS18780	COG0404	The glycine cleavage system catalyzes the degradation of glycine
XA10_RS18790	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XA10_RS18800	COG2081	HI0933 family
XA10_RS18830	COG0717	Belongs to the dCTP deaminase family
XA10_RS18845	COG0489	protein tyrosine kinase activity
XA10_RS18855	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XA10_RS18855	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XA10_RS18860	COG1054	Belongs to the UPF0176 family
XA10_RS18895	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
XA10_RS18900	COG1280	lysine exporter protein (LysE YggA)
XA10_RS18905	COG0513	Belongs to the DEAD box helicase family
XA10_RS18915	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
XA10_RS18935	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XA10_RS18950	COG2226	methyltransferase
XA10_RS18955	COG0745	RESPONSE REGULATOR receiver
XA10_RS18960	COG5002	protein histidine kinase activity
XA10_RS18970	COG5002	protein histidine kinase activity
XA10_RS18980	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XA10_RS18985	COG0583	DNA-binding transcription factor activity
XA10_RS18995	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
XA10_RS19000	COG1984	allophanate hydrolase subunit 2
XA10_RS19015	COG3181	Tripartite tricarboxylate transporter family receptor
XA10_RS19030	COG1024	Enoyl-CoA hydratase
XA10_RS19045	COG1802	Transcriptional regulator
XA10_RS19060	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
XA10_RS19065	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
XA10_RS19080	COG0583	DNA-binding transcription factor activity
XA10_RS19090	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
XA10_RS19100	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
XA10_RS19105	COG0154	amidase activity
XA10_RS19115	COG1609	Transcriptional regulator
XA10_RS19135	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
XA10_RS19155	COG2814	Major facilitator Superfamily
XA10_RS19160	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
XA10_RS19180	COG1999	signal sequence binding
XA10_RS19185	COG0109	protoheme IX farnesyltransferase activity
XA10_RS19225	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XA10_RS19245	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
XA10_RS19250	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XA10_RS19260	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
XA10_RS19265	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
XA10_RS19275	COG0070	glutamate synthase
XA10_RS19275	COG0067	glutamate synthase
XA10_RS19275	COG0069	glutamate synthase activity
XA10_RS19285	COG3047	cAMP biosynthetic process
XA10_RS19295	COG1127	ABC transporter
XA10_RS19300	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XA10_RS19305	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XA10_RS19310	COG2853	Lipoprotein
XA10_RS19320	COG1131	(ABC) transporter
XA10_RS19325	COG0842	Transport permease protein
XA10_RS19335	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
XA10_RS19340	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
XA10_RS19345	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
XA10_RS19350	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XA10_RS19355	COG0131	Imidazoleglycerol-phosphate dehydratase
XA10_RS19360	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
XA10_RS19365	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
XA10_RS19370	COG0107	imidazoleglycerol-phosphate synthase activity
XA10_RS19375	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
XA10_RS19380	COG0140	phosphoribosyl-ATP diphosphatase activity
XA10_RS19385	COG0537	adenosine 5'-monophosphoramidase activity
XA10_RS19390	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XA10_RS19395	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XA10_RS19410	COG3181	Tripartite tricarboxylate transporter family receptor
XA10_RS19445	COG3702	type iv secretory pathway
XA10_RS19450	COG3451	type IV secretory pathway VirB4
XA10_RS19465	COG3736	Type IV secretory pathway, component VirB8
XA10_RS19470	COG3504	Conjugal transfer protein
XA10_RS19475	COG2948	multi-organism process
XA10_RS19480	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
XA10_RS19490	COG0697	spore germination
XA10_RS19510	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
XA10_RS19515	COG0747	negative chemotaxis
XA10_RS19520	COG0601	transmembrane transport
XA10_RS19525	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XA10_RS19530	COG0444	Belongs to the ABC transporter superfamily
XA10_RS19540	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
XA10_RS19550	COG0494	nUDIX hydrolase
XA10_RS19590	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
XA10_RS19595	COG0237	dephospho-CoA kinase activity
XA10_RS19600	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
XA10_RS19615	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
XA10_RS19620	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
XA10_RS19630	COG0477	Major facilitator Superfamily
XA10_RS19635	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
XA10_RS19650	COG1126	abc transporter atp-binding protein
XA10_RS19655	COG0765	amino acid transport
XA10_RS19660	COG4597	amino acid ABC transporter
XA10_RS19665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XA10_RS19670	COG2884	Cell division ATP-binding protein ftsE
XA10_RS19675	COG2177	Part of the ABC transporter FtsEX involved in
XA10_RS19680	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
XA10_RS19690	COG1194	a g-specific adenine glycosylase
XA10_RS19700	COG2226	methyltransferase
XA10_RS19710	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XA10_RS19715	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XA10_RS19730	COG1024	Enoyl-CoA hydratase
XA10_RS19750	COG1024	Enoyl-CoA hydratase
XA10_RS19755	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XA10_RS19760	COG3181	Tripartite tricarboxylate transporter family receptor
XA10_RS19770	COG0753	catalase activity
XA10_RS19775	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XA10_RS19780	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
XA10_RS19790	COG2175	clavaminate synthase activity
XA10_RS19795	COG1473	amidohydrolase
XA10_RS19800	COG4608	Belongs to the ABC transporter superfamily
XA10_RS19805	COG0444	Belongs to the ABC transporter superfamily
XA10_RS19820	COG0747	negative chemotaxis
XA10_RS19825	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
XA10_RS19860	COG0436	Aminotransferase
XA10_RS19865	COG1278	Cold shock