locus-tag	class	description
CG025_RS00005	COG0445	tRNA wobble uridine modification
CG025_RS00010	COG0357	Ribosomal RNA small subunit methyltransferase G
CG025_RS00015	COG1192	Involved in chromosome partitioning
CG025_RS00025	COG1475	DNA binding
CG025_RS00050	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CG025_RS00060	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CG025_RS00070	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CG025_RS00075	COG0081	regulation of translation
CG025_RS00080	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CG025_RS00085	COG0222	ribosome binding
CG025_RS00090	COG0085	RNA polymerase activity
CG025_RS00095	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CG025_RS00135	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CG025_RS00160	COG1024	Enoyl-CoA hydratase
CG025_RS00180	COG0752	glycyl-tRNA synthetase alpha subunit
CG025_RS00185	COG0751	glycine-tRNA ligase activity
CG025_RS00190	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CG025_RS00195	COG0204	Acyl-transferase
CG025_RS00210	COG0242	peptide deformylase activity
CG025_RS00250	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CG025_RS00255	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CG025_RS00255	COG2813	Specifically methylates the guanine in position
CG025_RS00270	COG2223	nitrite transmembrane transporter activity
CG025_RS00280	COG1794	racemase activity, acting on amino acids and derivatives
CG025_RS00285	COG1126	abc transporter atp-binding protein
CG025_RS00290	COG0765	amino acid transport
CG025_RS00295	COG0765	amino acid transport
CG025_RS00300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG025_RS00365	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CG025_RS00395	COG0326	Molecular chaperone. Has ATPase activity
CG025_RS00400	COG0625	glutathione transferase activity
CG025_RS00415	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CG025_RS00420	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CG025_RS00450	COG0438	transferase activity, transferring glycosyl groups
CG025_RS00455	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CG025_RS00460	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CG025_RS00490	COG0859	PFAM glycosyl transferase family 9
CG025_RS00505	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CG025_RS00515	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CG025_RS00520	COG1127	ABC transporter
CG025_RS00540	COG1686	Belongs to the peptidase S11 family
CG025_RS00550	COG2921	Belongs to the UPF0250 family
CG025_RS00555	COG0321	lipoyl(octanoyl) transferase activity
CG025_RS00560	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CG025_RS00595	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CG025_RS00605	COG0018	arginyl-trna synthetase
CG025_RS00625	COG0395	ABC-type sugar transport system, permease component
CG025_RS00630	COG1175	transmembrane transport
CG025_RS00635	COG1653	transport
CG025_RS00640	COG3842	ATPase activity
CG025_RS00645	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CG025_RS00655	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CG025_RS00675	COG1609	Transcriptional regulator
CG025_RS00685	COG0154	amidase activity
CG025_RS00690	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CG025_RS00700	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CG025_RS00710	COG0583	DNA-binding transcription factor activity
CG025_RS00730	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CG025_RS00745	COG1802	Transcriptional regulator
CG025_RS00760	COG1024	Enoyl-CoA hydratase
CG025_RS00770	COG3181	Tripartite tricarboxylate transporter family receptor
CG025_RS00785	COG1984	allophanate hydrolase subunit 2
CG025_RS00790	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CG025_RS00800	COG0583	DNA-binding transcription factor activity
CG025_RS00805	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CG025_RS00815	COG5002	protein histidine kinase activity
CG025_RS00825	COG5002	protein histidine kinase activity
CG025_RS00830	COG0745	RESPONSE REGULATOR receiver
CG025_RS00835	COG2226	methyltransferase
CG025_RS00850	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CG025_RS00870	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CG025_RS00880	COG0513	Belongs to the DEAD box helicase family
CG025_RS00885	COG1280	lysine exporter protein (LysE YggA)
CG025_RS00890	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CG025_RS00930	COG1054	Belongs to the UPF0176 family
CG025_RS00935	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CG025_RS00935	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CG025_RS00945	COG0489	protein tyrosine kinase activity
CG025_RS00960	COG0717	Belongs to the dCTP deaminase family
CG025_RS00990	COG2081	HI0933 family
CG025_RS01000	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CG025_RS01010	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CG025_RS01015	COG0509	glycine decarboxylation via glycine cleavage system
CG025_RS01020	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CG025_RS01020	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CG025_RS01060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CG025_RS01075	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CG025_RS01085	COG1414	Transcriptional regulator
CG025_RS01090	COG1028	Short-chain dehydrogenase reductase Sdr
CG025_RS01095	COG2031	fatty acid transporter
CG025_RS01100	COG1250	3-hydroxyacyl-CoA dehydrogenase
CG025_RS01110	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CG025_RS01115	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CG025_RS01125	COG4257	antibiotic catabolic process
CG025_RS01145	COG1012	belongs to the aldehyde dehydrogenase family
CG025_RS01150	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CG025_RS01155	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CG025_RS01180	COG1028	Short-chain dehydrogenase reductase Sdr
CG025_RS01190	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CG025_RS01200	COG2188	Transcriptional regulator
CG025_RS01205	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CG025_RS01230	COG0617	tRNA 3'-terminal CCA addition
CG025_RS01245	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CG025_RS01250	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CG025_RS01255	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CG025_RS01260	COG0586	Pfam SNARE associated Golgi protein
CG025_RS01265	COG0860	N-Acetylmuramoyl-L-alanine amidase
CG025_RS01270	COG0802	atpase or kinase
CG025_RS01275	COG0114	fumarate hydratase activity
CG025_RS01285	COG3181	Tripartite tricarboxylate transporter family receptor
CG025_RS01295	COG0405	Gamma-glutamyltransferase
CG025_RS01300	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CG025_RS01335	COG1294	oxidase, subunit
CG025_RS01345	COG4988	ABC transporter
CG025_RS01350	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CG025_RS01400	COG2969	positive regulation of protein catabolic process
CG025_RS01405	COG0625	glutathione transferase activity
CG025_RS01410	COG2857	Cytochrome c1
CG025_RS01415	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CG025_RS01420	COG0723	plastoquinol--plastocyanin reductase activity
CG025_RS01425	COG1970	mechanosensitive ion channel activity
CG025_RS01430	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CG025_RS01445	COG2808	Putative FMN-binding domain
CG025_RS01450	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CG025_RS01455	COG0747	negative chemotaxis
CG025_RS01460	COG0657	acetylesterase activity
CG025_RS01470	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CG025_RS01475	COG2207	Transcriptional regulator
CG025_RS01480	COG0129	dihydroxy-acid dehydratase activity
CG025_RS01485	COG2814	Major facilitator Superfamily
CG025_RS01490	COG0583	DNA-binding transcription factor activity
CG025_RS01500	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
CG025_RS01570	COG1024	Enoyl-CoA hydratase
CG025_RS01575	COG1960	acyl-CoA dehydrogenase activity
CG025_RS01600	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CG025_RS01605	COG0352	thiamine-phosphate diphosphorylase activity
CG025_RS01620	COG1678	Uncharacterized ACR, COG1678
CG025_RS01625	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CG025_RS01630	COG0540	Belongs to the ATCase OTCase family
CG025_RS01645	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CG025_RS01655	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CG025_RS01690	COG1234	tRNA 3'-trailer cleavage
CG025_RS01710	COG3064	Membrane
CG025_RS01740	COG1683	Conserved Protein
CG025_RS01745	COG1120	ATPase activity
CG025_RS01750	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CG025_RS01755	COG4558	Periplasmic binding protein
CG025_RS01760	COG3720	iron ion transport
CG025_RS01770	COG3712	iron ion homeostasis
CG025_RS01775	COG1595	DNA-templated transcription, initiation
CG025_RS01810	COG1802	Transcriptional regulator
CG025_RS01820	COG3069	C4-dicarboxylate transmembrane transporter activity
CG025_RS01830	COG1012	belongs to the aldehyde dehydrogenase family
CG025_RS01865	COG2860	membrane
CG025_RS01870	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CG025_RS01875	COG0708	Exodeoxyribonuclease III
CG025_RS01880	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CG025_RS01885	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CG025_RS01890	COG0154	amidase activity
CG025_RS01895	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CG025_RS01900	COG1077	Cell shape determining protein MreB Mrl
CG025_RS01905	COG1792	Involved in formation and maintenance of cell shape
CG025_RS01915	COG0768	penicillin binding
CG025_RS01920	COG0772	Belongs to the SEDS family
CG025_RS01925	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CG025_RS01930	COG0471	metal ion transport
CG025_RS01935	COG1309	transcriptional regulator
CG025_RS01945	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CG025_RS01960	COG2823	Periplasmic or secreted lipoprotein
CG025_RS01965	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CG025_RS01980	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CG025_RS02000	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CG025_RS02010	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CG025_RS02030	COG0492	ferredoxin-NADP+ reductase activity
CG025_RS02040	COG3181	Tripartite tricarboxylate transporter family receptor
CG025_RS02045	COG1250	3-hydroxyacyl-CoA dehydrogenase
CG025_RS02045	COG1024	Enoyl-CoA hydratase
CG025_RS02050	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CG025_RS02055	COG0028	Belongs to the TPP enzyme family
CG025_RS02080	COG3181	Tripartite tricarboxylate transporter family receptor
CG025_RS02095	COG0697	spore germination
CG025_RS02125	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CG025_RS02130	COG0463	Glycosyl transferase, family 2
CG025_RS02145	COG0786	glutamate:sodium symporter activity
CG025_RS02155	COG2031	fatty acid transporter
CG025_RS02170	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CG025_RS02185	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CG025_RS02200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CG025_RS02210	COG1285	pathogenesis
CG025_RS02215	COG1253	flavin adenine dinucleotide binding
CG025_RS02220	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CG025_RS02225	COG1024	Enoyl-CoA hydratase
CG025_RS02230	COG3181	Tripartite tricarboxylate transporter family receptor
CG025_RS02235	COG0583	DNA-binding transcription factor activity
CG025_RS02240	COG1960	acyl-CoA dehydrogenase activity
CG025_RS02250	COG0183	Belongs to the thiolase family
CG025_RS02265	COG0583	DNA-binding transcription factor activity
CG025_RS02270	COG1278	Cold shock
CG025_RS02280	COG1802	Transcriptional regulator
CG025_RS02285	COG1012	belongs to the aldehyde dehydrogenase family
CG025_RS02290	COG2031	fatty acid transporter
CG025_RS02295	COG1017	nitric oxide dioxygenase activity
CG025_RS02295	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CG025_RS02300	COG0251	oxidation-reduction process
CG025_RS02320	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CG025_RS02330	COG0583	DNA-binding transcription factor activity
CG025_RS02335	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CG025_RS02350	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CG025_RS02355	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CG025_RS02360	COG0546	phosphoglycolate phosphatase activity
CG025_RS02370	COG1530	ribonuclease E activity
CG025_RS02390	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CG025_RS02395	COG0159	tryptophan synthase activity
CG025_RS02400	COG0133	tryptophan synthase activity
CG025_RS02410	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CG025_RS02415	COG3228	Belongs to the MtfA family
CG025_RS02425	COG0251	oxidation-reduction process
CG025_RS02430	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CG025_RS02435	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CG025_RS02450	COG2878	Part of a membrane complex involved in electron transport
CG025_RS02455	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CG025_RS02490	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CG025_RS02510	COG1268	BioY protein
CG025_RS02515	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CG025_RS02520	COG1122	ATPase activity
CG025_RS02525	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CG025_RS02540	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CG025_RS02545	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CG025_RS02555	COG1196	nuclear chromosome segregation
CG025_RS02560	COG0477	Major facilitator Superfamily
CG025_RS02565	COG1573	uracil-dna glycosylase
CG025_RS02570	COG1214	PFAM Peptidase M22, glycoprotease
CG025_RS02590	COG0450	alkyl hydroperoxide reductase
CG025_RS02595	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CG025_RS02605	COG2223	nitrite transmembrane transporter activity
CG025_RS02615	COG2186	Transcriptional regulator
CG025_RS02635	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CG025_RS02645	COG0583	DNA-binding transcription factor activity
CG025_RS02655	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CG025_RS02660	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CG025_RS02665	COG0137	argininosuccinate synthase activity
CG025_RS02670	COG3158	transport of potassium into the cell
CG025_RS02675	COG0642	Histidine kinase
CG025_RS02705	COG0776	regulation of translation
CG025_RS02710	COG3128	pkhd-type hydroxylase
CG025_RS02720	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CG025_RS02725	COG0557	exoribonuclease II activity
CG025_RS02750	COG0679	Auxin Efflux Carrier
CG025_RS02755	COG2391	methyltransferase activity
CG025_RS02760	COG0069	glutamate synthase activity
CG025_RS02770	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CG025_RS02780	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
CG025_RS02820	COG3706	GGDEF domain
CG025_RS02845	COG1053	succinate dehydrogenase
CG025_RS02850	COG0583	DNA-binding transcription factor activity
CG025_RS02865	COG1053	succinate dehydrogenase
CG025_RS02885	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CG025_RS02890	COG0459	protein refolding
CG025_RS02895	COG3468	outer membrane autotransporter barrel domain protein
CG025_RS02910	COG1252	NADH dehydrogenase
CG025_RS02915	COG0284	orotidine-5'-phosphate decarboxylase activity
CG025_RS02920	COG1058	Belongs to the CinA family
CG025_RS02920	COG1546	Belongs to the CinA family
CG025_RS02925	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CG025_RS02935	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CG025_RS02940	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CG025_RS02980	COG3639	organic phosphonate transmembrane transporter activity
CG025_RS02985	COG3639	organic phosphonate transmembrane transporter activity
CG025_RS03005	COG0742	ribosomal rna small subunit methyltransferase
CG025_RS03010	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CG025_RS03015	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CG025_RS03020	COG3135	benzoate transporter
CG025_RS03035	COG0640	Transcriptional regulator
CG025_RS03065	COG4172	Belongs to the ABC transporter superfamily
CG025_RS03070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CG025_RS03075	COG0601	transmembrane transport
CG025_RS03085	COG0280	phosphate acetyltransferase
CG025_RS03085	COG0281	malic enzyme
CG025_RS03145	COG0583	DNA-binding transcription factor activity
CG025_RS03160	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CG025_RS03165	COG0167	dihydroorotate dehydrogenase activity
CG025_RS03185	COG1414	Transcriptional regulator
CG025_RS03190	COG1546	Belongs to the CinA family
CG025_RS03190	COG1058	Belongs to the CinA family
CG025_RS03210	COG0513	Belongs to the DEAD box helicase family
CG025_RS03240	COG0429	hydrolase of the alpha beta-hydrolase fold
CG025_RS03245	COG4783	chaperone-mediated protein folding
CG025_RS03260	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CG025_RS03285	COG0006	proline dipeptidase activity
CG025_RS03295	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CG025_RS03315	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CG025_RS03320	COG0632	four-way junction helicase activity
CG025_RS03335	COG2255	four-way junction helicase activity
CG025_RS03340	COG0514	ATP-dependent DNA helicase (RecQ)
CG025_RS03355	COG0288	reversible hydration of carbon dioxide
CG025_RS03360	COG0154	amidase activity
CG025_RS03370	COG4211	Belongs to the binding-protein-dependent transport system permease family
CG025_RS03400	COG1464	Belongs to the NlpA lipoprotein family
CG025_RS03540	COG1196	nuclear chromosome segregation
CG025_RS03615	COG2135	peptidase activity
CG025_RS03630	COG0494	nUDIX hydrolase
CG025_RS03635	COG0442	prolyl-tRNA aminoacylation
CG025_RS03640	COG0824	Thioesterase
CG025_RS03645	COG0811	peptide transport
CG025_RS03650	COG0848	biopolymer transport protein
CG025_RS03660	COG0823	Involved in the tonB-independent uptake of proteins
CG025_RS03675	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CG025_RS03680	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CG025_RS03715	COG0700	Nucleoside recognition
CG025_RS03720	COG0469	pyruvate kinase activity
CG025_RS03725	COG1929	Belongs to the glycerate kinase type-1 family
CG025_RS03730	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CG025_RS03735	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CG025_RS03740	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CG025_RS03750	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CG025_RS03760	COG2154	pterin-4-alpha-carbinolamine dehydratase
CG025_RS03785	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CG025_RS03790	COG0154	amidase activity
CG025_RS03800	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CG025_RS03805	COG0601	transmembrane transport
CG025_RS03810	COG0747	negative chemotaxis
CG025_RS03830	COG0019	diaminopimelate decarboxylase activity
CG025_RS03845	COG2353	YceI-like domain
CG025_RS03850	COG4774	siderophore transport
CG025_RS03855	COG3712	iron ion homeostasis
CG025_RS03900	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CG025_RS03905	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CG025_RS03910	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CG025_RS03915	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CG025_RS03925	COG0142	geranyltranstransferase activity
CG025_RS03935	COG0583	DNA-binding transcription factor activity
CG025_RS03945	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
CG025_RS03950	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CG025_RS03970	COG2994	toxin metabolic process
CG025_RS03980	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CG025_RS03985	COG2274	protein secretion by the type I secretion system
CG025_RS03990	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CG025_RS03995	COG1538	Outer membrane efflux protein
CG025_RS04015	COG0765	amino acid transport
CG025_RS04020	COG1126	abc transporter atp-binding protein
CG025_RS04040	COG1028	Short-chain dehydrogenase reductase Sdr
CG025_RS04050	COG1802	Transcriptional regulator
CG025_RS04060	COG1802	Transcriptional regulator
CG025_RS04070	COG0318	PFAM AMP-dependent synthetase and ligase
CG025_RS04080	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CG025_RS04100	COG0028	Belongs to the TPP enzyme family
CG025_RS04120	COG0308	aminopeptidase N
CG025_RS04125	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CG025_RS04140	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CG025_RS04145	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CG025_RS04150	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CG025_RS04155	COG0560	Phosphoserine phosphatase
CG025_RS04160	COG0583	DNA-binding transcription factor activity
CG025_RS04165	COG3181	Tripartite tricarboxylate transporter family receptor
CG025_RS04170	COG0028	Belongs to the TPP enzyme family
CG025_RS04185	COG4774	siderophore transport
CG025_RS04190	COG4774	siderophore transport
CG025_RS04200	COG1007	ATP synthesis coupled electron transport
CG025_RS04215	COG0713	ATP synthesis coupled electron transport
CG025_RS04225	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CG025_RS04230	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CG025_RS04235	COG1034	ATP synthesis coupled electron transport
CG025_RS04245	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CG025_RS04250	COG0649	NAD binding
CG025_RS04255	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CG025_RS04260	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CG025_RS04265	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CG025_RS04270	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CG025_RS04300	COG0671	phosphoesterase, PA-phosphatase related
CG025_RS04310	COG1597	lipid kinase activity
CG025_RS04315	COG0583	DNA-binding transcription factor activity
CG025_RS04320	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CG025_RS04335	COG1733	regulation of RNA biosynthetic process
CG025_RS04340	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CG025_RS04345	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CG025_RS04360	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
CG025_RS04380	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CG025_RS04400	COG3608	succinylglutamate desuccinylase aspartoacylase
CG025_RS04405	COG0626	cystathionine gamma-synthase activity
CG025_RS04410	COG0583	DNA-binding transcription factor activity
CG025_RS04445	COG3799	methylaspartate ammonia-lyase activity
CG025_RS04455	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CG025_RS04465	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CG025_RS04470	COG0149	triose-phosphate isomerase activity
CG025_RS04490	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CG025_RS04505	COG1185	polyribonucleotide nucleotidyltransferase activity
CG025_RS04510	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CG025_RS04525	COG1183	phosphatidylcholine synthase activity
CG025_RS04530	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CG025_RS04535	COG0440	acetolactate synthase activity
CG025_RS04540	COG0028	Belongs to the TPP enzyme family
CG025_RS04555	COG5265	(ABC) transporter
CG025_RS04560	COG0500	methyltransferase
CG025_RS04580	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CG025_RS04600	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CG025_RS04610	COG0511	ligase activity, forming carbon-carbon bonds
CG025_RS04635	COG2188	Transcriptional regulator
CG025_RS04640	COG0439	Biotin carboxylase
CG025_RS04690	COG5265	(ABC) transporter
CG025_RS04700	COG0667	Aldo Keto reductase
CG025_RS04715	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CG025_RS04755	COG0583	DNA-binding transcription factor activity
CG025_RS04785	COG2814	Major facilitator Superfamily
CG025_RS04795	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CG025_RS04810	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CG025_RS04820	COG0287	Prephenate dehydrogenase
CG025_RS04825	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CG025_RS04830	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CG025_RS04850	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CG025_RS04855	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CG025_RS04860	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CG025_RS04865	COG1596	polysaccharide export
CG025_RS04865	COG1555	photosystem II stabilization
CG025_RS04880	COG2951	lytic endotransglycosylase activity
CG025_RS04885	COG0123	including yeast histone deacetylase and acetoin utilization protein
CG025_RS04900	COG1960	acyl-CoA dehydrogenase activity
CG025_RS04905	COG0450	alkyl hydroperoxide reductase
CG025_RS04925	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CG025_RS04960	COG0335	large ribosomal subunit rRNA binding
CG025_RS04975	COG0667	Aldo Keto reductase
CG025_RS04990	COG3161	chorismate lyase activity
CG025_RS04995	COG1187	pseudouridine synthase activity
CG025_RS05025	COG1999	signal sequence binding
CG025_RS05030	COG0339	signal peptide processing
CG025_RS05035	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CG025_RS05040	COG4566	intracellular signal transduction
CG025_RS05050	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CG025_RS05055	COG0508	dehydrogenase complex catalyzes the overall conversion of
CG025_RS05060	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CG025_RS05065	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CG025_RS05075	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CG025_RS05080	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CG025_RS05085	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CG025_RS05090	COG0126	phosphoglycerate kinase activity
CG025_RS05095	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CG025_RS05100	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CG025_RS05115	COG0625	glutathione transferase activity
CG025_RS05145	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CG025_RS05155	COG0521	Mo-molybdopterin cofactor biosynthetic process
CG025_RS05165	COG0739	heme binding
CG025_RS05175	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CG025_RS05215	COG0745	RESPONSE REGULATOR receiver
CG025_RS05230	COG0840	transmembrane signaling receptor activity
CG025_RS05240	COG2201	protein-glutamate methylesterase activity
CG025_RS05245	COG0745	RESPONSE REGULATOR receiver
CG025_RS05250	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CG025_RS05275	COG0667	Aldo Keto reductase
CG025_RS05285	COG4535	Mg2 and Co2 transporter CorC
CG025_RS05290	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CG025_RS05295	COG1702	phosphate starvation-inducible protein PhoH
CG025_RS05300	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CG025_RS05315	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CG025_RS05320	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CG025_RS05325	COG1862	Preprotein translocase
CG025_RS05330	COG0343	queuine tRNA-ribosyltransferase activity
CG025_RS05335	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CG025_RS05340	COG2027	D-alanyl-D-alanine carboxypeptidase
CG025_RS05345	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CG025_RS05355	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CG025_RS05360	COG3468	outer membrane autotransporter barrel domain protein
CG025_RS05365	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CG025_RS05365	COG1648	precorrin-2 dehydrogenase activity
CG025_RS05390	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CG025_RS05395	COG0741	lytic transglycosylase activity
CG025_RS05405	COG0436	Aminotransferase
CG025_RS05415	COG0281	malic enzyme
CG025_RS05415	COG0280	phosphate acetyltransferase
CG025_RS05425	COG2732	(Barnase) inhibitor
CG025_RS05440	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CG025_RS05465	COG0248	Ppx GppA phosphatase
CG025_RS05475	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CG025_RS05485	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CG025_RS05490	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CG025_RS05495	COG1534	Rna-binding protein
CG025_RS05525	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CG025_RS05540	COG1295	ribonuclease BN
CG025_RS05550	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CG025_RS05555	COG0745	RESPONSE REGULATOR receiver
CG025_RS05560	COG2205	protein histidine kinase activity
CG025_RS05595	COG1022	Amp-dependent synthetase and ligase
CG025_RS05610	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CG025_RS05615	COG1028	Short-chain dehydrogenase reductase Sdr
CG025_RS05625	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CG025_RS05640	COG1136	(ABC) transporter
CG025_RS05645	COG0084	hydrolase, TatD family'
CG025_RS05670	COG2333	competence protein COMEC
CG025_RS05670	COG0658	competence protein
CG025_RS05680	COG0613	PHP domain protein
CG025_RS05700	COG3539	Fimbrial protein
CG025_RS05705	COG0281	malic enzyme
CG025_RS05705	COG0280	phosphate acetyltransferase
CG025_RS05715	COG1522	sequence-specific DNA binding
CG025_RS05725	COG0567	Dehydrogenase, E1 component
CG025_RS05730	COG0508	dehydrogenase complex catalyzes the overall conversion of
CG025_RS05735	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CG025_RS05740	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CG025_RS05745	COG1028	Short-chain dehydrogenase reductase Sdr
CG025_RS05750	COG0583	DNA-binding transcription factor activity
CG025_RS05760	COG3181	Tripartite tricarboxylate transporter family receptor
CG025_RS05785	COG0180	Tryptophanyl-tRNA synthetase
CG025_RS05790	COG2183	response to ionizing radiation
CG025_RS05795	COG1199	ATP-dependent helicase activity
CG025_RS05805	COG0564	pseudouridine synthase activity
CG025_RS05815	COG3243	poly(R)-hydroxyalkanoic acid synthase
CG025_RS05820	COG1028	Short-chain dehydrogenase reductase Sdr
CG025_RS05825	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
CG025_RS05840	COG0672	)-iron permease
CG025_RS05880	COG0583	DNA-binding transcription factor activity
CG025_RS05890	COG2814	Major facilitator Superfamily
CG025_RS05905	COG1619	proteins homologs of microcin C7 resistance protein MccF
CG025_RS05920	COG2084	Dehydrogenase
CG025_RS05925	COG3181	Tripartite tricarboxylate transporter family receptor
CG025_RS05950	COG2988	succinylglutamate desuccinylase activity
CG025_RS05985	COG0765	amino acid transport
CG025_RS05990	COG0765	amino acid transport
CG025_RS05995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG025_RS06030	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CG025_RS06035	COG1595	DNA-templated transcription, initiation
CG025_RS06045	COG3530	Putative quorum-sensing-regulated virulence factor
CG025_RS06050	COG0494	nUDIX hydrolase
CG025_RS06065	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CG025_RS06070	COG0542	response to heat
CG025_RS06090	COG3468	outer membrane autotransporter barrel domain protein
CG025_RS06100	COG5441	Belongs to the UPF0261 family
CG025_RS06105	COG5564	TIM-barrel signal transduction protein
CG025_RS06120	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CG025_RS06135	COG1477	protein flavinylation
CG025_RS06155	COG1131	(ABC) transporter
CG025_RS06160	COG0842	Transport permease protein
CG025_RS06170	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CG025_RS06175	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CG025_RS06175	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CG025_RS06180	COG1562	ergosterol biosynthetic process
CG025_RS06185	COG1562	ergosterol biosynthetic process
CG025_RS06190	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CG025_RS06195	COG1028	Short-chain dehydrogenase reductase Sdr
CG025_RS06215	COG2304	oxidoreductase activity
CG025_RS06235	COG0534	Mate efflux family protein
CG025_RS06245	COG0254	rRNA binding
CG025_RS06250	COG3483	tryptophan 2,3-dioxygenase activity
CG025_RS06255	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CG025_RS06260	COG2003	Belongs to the UPF0758 family
CG025_RS06265	COG1047	Peptidyl-prolyl cis-trans
CG025_RS06270	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CG025_RS06275	COG0625	glutathione transferase activity
CG025_RS06295	COG0523	cobalamin synthesis protein
CG025_RS06305	COG0583	DNA-binding transcription factor activity
CG025_RS06315	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CG025_RS06320	COG1187	pseudouridine synthase activity
CG025_RS06325	COG0779	Required for maturation of 30S ribosomal subunits
CG025_RS06330	COG2251	uridine kinase activity
CG025_RS06330	COG0195	Participates in both transcription termination and antitermination
CG025_RS06335	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CG025_RS06340	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CG025_RS06345	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CG025_RS06365	COG1611	Belongs to the LOG family
CG025_RS06380	COG0412	Dienelactone hydrolase
CG025_RS06385	COG1283	sodium-dependent phosphate transmembrane transporter activity
CG025_RS06390	COG1760	l-serine dehydratase
CG025_RS06395	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CG025_RS06400	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CG025_RS06410	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CG025_RS06435	COG2311	Membrane
CG025_RS06460	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CG025_RS06480	COG0559	Belongs to the binding-protein-dependent transport system permease family
CG025_RS06500	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CG025_RS06510	COG1653	transport
CG025_RS06515	COG1175	transmembrane transport
CG025_RS06520	COG0395	ABC-type sugar transport system, permease component
CG025_RS06525	COG3842	ATPase activity
CG025_RS06550	COG2363	Small membrane protein
CG025_RS06565	COG1464	Belongs to the NlpA lipoprotein family
CG025_RS06575	COG0688	phosphatidylethanolamine metabolic process
CG025_RS06590	COG0095	Lipoate-protein ligase
CG025_RS06605	COG0625	glutathione transferase activity
CG025_RS06610	COG0386	Belongs to the glutathione peroxidase family
CG025_RS06630	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CG025_RS06660	COG2259	Doxx family
CG025_RS06675	COG0667	Aldo Keto reductase
CG025_RS06705	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CG025_RS06725	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CG025_RS06735	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CG025_RS06785	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CG025_RS06790	COG3568	Endonuclease Exonuclease Phosphatase
CG025_RS06800	COG1695	Transcriptional regulator
CG025_RS06820	COG0583	DNA-binding transcription factor activity
CG025_RS06835	COG1802	Transcriptional regulator
CG025_RS06845	COG3181	Tripartite tricarboxylate transporter family receptor
CG025_RS06855	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CG025_RS06870	COG0066	3-isopropylmalate dehydratase activity
CG025_RS06880	COG3181	Tripartite tricarboxylate transporter family receptor
CG025_RS06885	COG4948	Mandelate Racemase Muconate Lactonizing
CG025_RS06900	COG1126	abc transporter atp-binding protein
CG025_RS06905	COG0765	amino acid transport
CG025_RS06910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG025_RS06950	COG1815	bacterial-type flagellum-dependent cell motility
CG025_RS06955	COG1558	bacterial-type flagellum-dependent cell motility
CG025_RS06965	COG1749	Flagellar hook protein flgE
CG025_RS06980	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CG025_RS06985	COG1706	bacterial-type flagellum-dependent cell motility
CG025_RS06995	COG1256	bacterial-type flagellum assembly
CG025_RS07005	COG0840	transmembrane signaling receptor activity
CG025_RS07010	COG0840	transmembrane signaling receptor activity
CG025_RS07015	COG0840	transmembrane signaling receptor activity
CG025_RS07035	COG1338	Plays a role in the flagellum-specific transport system
CG025_RS07055	COG1580	Controls the rotational direction of flagella during chemotaxis
CG025_RS07080	COG1157	protein secretion by the type III secretion system
CG025_RS07090	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CG025_RS07100	COG1677	Flagellar hook-basal body complex protein FliE
CG025_RS07110	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CG025_RS07145	COG0285	dihydrofolate synthase activity
CG025_RS07175	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CG025_RS07180	COG0024	Methionine aminopeptidase
CG025_RS07185	COG0052	Belongs to the universal ribosomal protein uS2 family
CG025_RS07190	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CG025_RS07195	COG0528	UMP kinase activity
CG025_RS07200	COG0233	cytoplasmic translational termination
CG025_RS07205	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CG025_RS07215	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CG025_RS07220	COG0750	zinc metalloprotease
CG025_RS07225	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CG025_RS07230	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CG025_RS07235	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CG025_RS07240	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CG025_RS07250	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CG025_RS07255	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CG025_RS07260	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CG025_RS07265	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CG025_RS07275	COG0519	Catalyzes the synthesis of GMP from XMP
CG025_RS07275	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CG025_RS07290	COG0330	HflC and HflK could
CG025_RS07295	COG3706	GGDEF domain
CG025_RS07300	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CG025_RS07310	COG2867	negative regulation of translational initiation
CG025_RS07320	COG1960	acyl-CoA dehydrogenase activity
CG025_RS07325	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CG025_RS07360	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CG025_RS07365	COG0505	Belongs to the CarA family
CG025_RS07370	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CG025_RS07380	COG0406	alpha-ribazole phosphatase activity
CG025_RS07390	COG3842	ATPase activity
CG025_RS07410	COG5001	Diguanylate cyclase
CG025_RS07415	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CG025_RS07425	COG1763	Mo-molybdopterin cofactor biosynthetic process
CG025_RS07430	COG0303	'Molybdopterin
CG025_RS07435	COG0746	molybdenum cofactor guanylyltransferase activity
CG025_RS07440	COG0489	protein tyrosine kinase activity
CG025_RS07470	COG0243	molybdopterin cofactor binding
CG025_RS07470	COG3383	formate dehydrogenase (NAD+) activity
CG025_RS07505	COG1122	ATPase activity
CG025_RS07515	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CG025_RS07520	COG0066	3-isopropylmalate dehydratase activity
CG025_RS07525	COG0473	3-isopropylmalate dehydrogenase activity
CG025_RS07530	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CG025_RS07540	COG0101	tRNA pseudouridine synthase activity
CG025_RS07545	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CG025_RS07560	COG0135	phosphoribosylanthranilate isomerase activity
CG025_RS07575	COG3022	response to hydroperoxide
CG025_RS07590	COG3023	N-Acetylmuramoyl-L-alanine amidase
CG025_RS07600	COG0424	maF-like protein
CG025_RS07605	COG1399	metal-binding, possibly nucleic acid-binding protein
CG025_RS07610	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CG025_RS07615	COG0416	fatty acid biosynthetic process
CG025_RS07620	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CG025_RS07635	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CG025_RS07640	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CG025_RS07665	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CG025_RS07670	COG0481	GTPase activity
CG025_RS07675	COG0681	Belongs to the peptidase S26 family
CG025_RS07680	COG0571	ribonuclease III activity
CG025_RS07685	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CG025_RS07690	COG1381	Involved in DNA repair and RecF pathway recombination
CG025_RS07700	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CG025_RS07715	COG3181	Tripartite tricarboxylate transporter family receptor
CG025_RS07720	COG0670	Belongs to the BI1 family
CG025_RS07735	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CG025_RS07745	COG0583	DNA-binding transcription factor activity
CG025_RS07760	COG0583	DNA-binding transcription factor activity
CG025_RS07775	COG0791	NLP P60 protein
CG025_RS07785	COG3193	protein, possibly involved in utilization of glycolate and propanediol
CG025_RS07795	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CG025_RS07800	COG0697	spore germination
CG025_RS07805	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CG025_RS07820	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CG025_RS07850	COG1446	asparaginase
CG025_RS07855	COG4172	Belongs to the ABC transporter superfamily
CG025_RS07860	COG0747	negative chemotaxis
CG025_RS07870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CG025_RS07895	COG0504	CTP synthase activity
CG025_RS07900	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CG025_RS07910	COG0148	phosphopyruvate hydratase activity
CG025_RS07915	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CG025_RS07945	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CG025_RS07955	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CG025_RS07980	COG1981	membrane
CG025_RS08010	COG0039	L-malate dehydrogenase activity
CG025_RS08015	COG2188	Transcriptional regulator
CG025_RS08020	COG2009	succinate dehydrogenase
CG025_RS08025	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CG025_RS08030	COG1053	succinate dehydrogenase
CG025_RS08035	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CG025_RS08040	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CG025_RS08045	COG0372	Belongs to the citrate synthase family
CG025_RS08060	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CG025_RS08060	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CG025_RS08070	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CG025_RS08075	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CG025_RS08090	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CG025_RS08095	COG3842	ATPase activity
CG025_RS08100	COG1176	ABC-type spermidine putrescine transport system, permease component I
CG025_RS08105	COG1177	transmembrane transport
CG025_RS08130	COG1960	acyl-CoA dehydrogenase activity
CG025_RS08135	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CG025_RS08140	COG0704	Plays a role in the regulation of phosphate uptake
CG025_RS08150	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CG025_RS08155	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CG025_RS08155	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CG025_RS08160	COG1643	Atp-dependent helicase
CG025_RS08175	COG0438	transferase activity, transferring glycosyl groups
CG025_RS08180	COG0726	polysaccharide deacetylase
CG025_RS08185	COG0463	Glycosyl transferase, family 2
CG025_RS08190	COG0438	transferase activity, transferring glycosyl groups
CG025_RS08195	COG2194	sulfuric ester hydrolase activity
CG025_RS08220	COG0859	PFAM glycosyl transferase family 9
CG025_RS08225	COG1132	(ABC) transporter
CG025_RS08240	COG0077	Prephenate dehydratase
CG025_RS08245	COG1530	ribonuclease E activity
CG025_RS08285	COG3468	outer membrane autotransporter barrel domain protein
CG025_RS08290	COG0424	maF-like protein
CG025_RS08295	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CG025_RS08300	COG0799	negative regulation of ribosome biogenesis
CG025_RS08305	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CG025_RS08310	COG0408	coproporphyrinogen oxidase activity
CG025_RS08315	COG0151	Belongs to the GarS family
CG025_RS08320	COG0217	transcriptional regulatory protein
CG025_RS08325	COG0433	COG0433 Predicted ATPase
CG025_RS08330	COG1115	amino acid carrier protein
CG025_RS08335	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CG025_RS08345	COG1012	belongs to the aldehyde dehydrogenase family
CG025_RS08370	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CG025_RS08385	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CG025_RS08395	COG0747	negative chemotaxis
CG025_RS08405	COG0473	3-isopropylmalate dehydrogenase activity
CG025_RS08410	COG2814	Major facilitator Superfamily
CG025_RS08415	COG1566	PFAM secretion protein HlyD family protein
CG025_RS08425	COG1846	Transcriptional regulator
CG025_RS08435	COG0697	spore germination
CG025_RS08445	COG0501	Belongs to the peptidase M48B family
CG025_RS08465	COG0583	DNA-binding transcription factor activity
CG025_RS08470	COG3842	ATPase activity
CG025_RS08475	COG1178	ABC-type Fe3 transport system permease component
CG025_RS08480	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CG025_RS08485	COG1840	ABC-type Fe3 transport system, periplasmic component
CG025_RS08510	COG2233	PERMEase
CG025_RS08515	COG0840	transmembrane signaling receptor activity
CG025_RS08520	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CG025_RS08550	COG4789	Type iii secretion
CG025_RS08615	COG4669	(LipO)protein
CG025_RS08650	COG4790	Type iii secretion
CG025_RS08655	COG4794	Type iii secretion
CG025_RS08660	COG4791	protein targeting
CG025_RS08665	COG4792	protein secretion
CG025_RS08680	COG1595	DNA-templated transcription, initiation
CG025_RS08705	COG2208	phosphoserine phosphatase activity
CG025_RS08705	COG2770	Histidine kinase
CG025_RS08715	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CG025_RS08720	COG2172	sigma factor antagonist activity
CG025_RS08725	COG1366	Belongs to the anti-sigma-factor antagonist family
CG025_RS08730	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CG025_RS08770	COG2358	TRAP transporter, solute receptor (TAXI family
CG025_RS08775	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CG025_RS08805	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CG025_RS08815	COG2252	PERMEase
CG025_RS08820	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CG025_RS08830	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CG025_RS08835	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CG025_RS08865	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CG025_RS08870	COG0789	Transcriptional regulator
CG025_RS08880	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CG025_RS08880	COG0678	peroxiredoxin activity
CG025_RS08890	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CG025_RS08895	COG0584	glycerophosphoryl diester phosphodiesterase
CG025_RS08900	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CG025_RS08910	COG4181	ATPase activity
CG025_RS08925	COG2823	Periplasmic or secreted lipoprotein
CG025_RS08935	COG3237	CsbD-like
CG025_RS08940	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CG025_RS08940	COG1181	Belongs to the D-alanine--D-alanine ligase family
CG025_RS08945	COG0189	ligase activity
CG025_RS08945	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CG025_RS08965	COG2833	Protein of unknown function (DUF455)
CG025_RS08970	COG2951	lytic endotransglycosylase activity
CG025_RS08990	COG1522	sequence-specific DNA binding
CG025_RS09000	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CG025_RS09005	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CG025_RS09010	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CG025_RS09015	COG0196	riboflavin kinase activity
CG025_RS09020	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CG025_RS09040	COG0210	DNA helicase
CG025_RS09045	COG4771	TonB-dependent receptor
CG025_RS09050	COG0488	(ABC) transporter
CG025_RS09055	COG2890	protein-(glutamine-N5) methyltransferase activity
CG025_RS09060	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CG025_RS09065	COG2171	N-acyltransferase activity
CG025_RS09100	COG1278	Cold shock
CG025_RS09110	COG1278	Cold shock
CG025_RS09120	COG0544	peptidyl-prolyl cis-trans isomerase activity
CG025_RS09125	COG0740	serine-type endopeptidase activity
CG025_RS09130	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CG025_RS09135	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CG025_RS09140	COG0583	DNA-binding transcription factor activity
CG025_RS09145	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CG025_RS09160	COG1024	Enoyl-CoA hydratase
CG025_RS09170	COG0183	Belongs to the thiolase family
CG025_RS09175	COG1028	Short-chain dehydrogenase reductase Sdr
CG025_RS09195	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CG025_RS09225	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CG025_RS09235	COG0556	nucleotide-excision repair
CG025_RS09240	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CG025_RS09250	COG1104	cysteine desulfurase activity
CG025_RS09255	COG0822	iron-sulfur transferase activity
CG025_RS09260	COG0316	Belongs to the HesB IscA family
CG025_RS09265	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CG025_RS09270	COG0443	Heat shock 70 kDa protein
CG025_RS09275	COG0633	Ferredoxin
CG025_RS09295	COG1024	Enoyl-CoA hydratase
CG025_RS09320	COG3395	kinase activity
CG025_RS09340	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CG025_RS09350	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CG025_RS09380	COG0747	negative chemotaxis
CG025_RS09385	COG0601	transmembrane transport
CG025_RS09400	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CG025_RS09405	COG4172	Belongs to the ABC transporter superfamily
CG025_RS09410	COG0154	amidase activity
CG025_RS09455	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CG025_RS09460	COG0425	Belongs to the sulfur carrier protein TusA family
CG025_RS09470	COG0228	four-way junction DNA binding
CG025_RS09475	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CG025_RS09480	COG0336	Belongs to the RNA methyltransferase TrmD family
CG025_RS09485	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CG025_RS09510	COG0642	Histidine kinase
CG025_RS09525	COG0525	valine-tRNA ligase activity
CG025_RS09530	COG0105	UTP biosynthetic process
CG025_RS09535	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CG025_RS09545	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CG025_RS09550	COG0124	histidyl-tRNA synthetase
CG025_RS09555	COG2976	Protein conserved in bacteria
CG025_RS09560	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CG025_RS09565	COG1160	GTP binding
CG025_RS09570	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CG025_RS09575	COG1923	regulation of RNA biosynthetic process
CG025_RS09580	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CG025_RS09585	COG0330	HflC and HflK could
CG025_RS09590	COG0330	HflC and HflK could
CG025_RS09595	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CG025_RS09600	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CG025_RS09605	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CG025_RS09610	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CG025_RS09620	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CG025_RS09655	COG0628	permease
CG025_RS09660	COG0842	Transport permease protein
CG025_RS09665	COG1131	(ABC) transporter
CG025_RS09735	COG0156	8-amino-7-oxononanoate synthase activity
CG025_RS09745	COG4106	trans-aconitate 2-methyltransferase activity
CG025_RS09745	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CG025_RS09750	COG1380	Effector of murein hydrolase LrgA
CG025_RS09775	COG3284	Transcriptional regulator
CG025_RS09780	COG1012	belongs to the aldehyde dehydrogenase family
CG025_RS09795	COG2733	membrane
CG025_RS09800	COG0583	DNA-binding transcription factor activity
CG025_RS09805	COG0384	phenazine biosynthesis protein PhzF
CG025_RS09810	COG5507	3-demethylubiquinone-9 3-methyltransferase
CG025_RS09815	COG2169	Transcriptional regulator
CG025_RS09845	COG0659	secondary active sulfate transmembrane transporter activity
CG025_RS09870	COG1132	(ABC) transporter
CG025_RS09920	COG2207	Transcriptional regulator
CG025_RS10060	COG2346	COG2346, Truncated hemoglobins
CG025_RS10090	COG0583	DNA-binding transcription factor activity
CG025_RS10105	COG0183	Belongs to the thiolase family
CG025_RS10120	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CG025_RS10125	COG0633	Ferredoxin
CG025_RS10135	COG1024	Enoyl-CoA hydratase
CG025_RS10145	COG4638	Rieske (2fe-2S)
CG025_RS10155	COG0559	Belongs to the binding-protein-dependent transport system permease family
CG025_RS10175	COG2224	Isocitrate lyase
CG025_RS10180	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CG025_RS10180	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CG025_RS10190	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CG025_RS10195	COG0322	excinuclease ABC activity
CG025_RS10200	COG1472	Belongs to the glycosyl hydrolase 3 family
CG025_RS10205	COG0736	holo-[acyl-carrier-protein] synthase activity
CG025_RS10210	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CG025_RS10220	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CG025_RS10225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CG025_RS10250	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CG025_RS10265	COG2032	superoxide dismutase activity
CG025_RS10280	COG1024	Enoyl-CoA hydratase
CG025_RS10290	COG1802	Transcriptional regulator
CG025_RS10300	COG0183	Belongs to the thiolase family
CG025_RS10305	COG1942	4-Oxalocrotonate Tautomerase
CG025_RS10315	COG4176	ABC-type proline glycine betaine transport system permease component
CG025_RS10335	COG2814	Major facilitator Superfamily
CG025_RS10340	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CG025_RS10345	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CG025_RS10380	COG2814	Major facilitator Superfamily
CG025_RS10385	COG0495	leucyl-tRNA aminoacylation
CG025_RS10400	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CG025_RS10410	COG0154	amidase activity
CG025_RS10415	COG1250	3-hydroxyacyl-CoA dehydrogenase
CG025_RS10470	COG0427	acetyl-CoA hydrolase
CG025_RS10475	COG0583	DNA-binding transcription factor activity
CG025_RS10495	COG0730	response to heat
CG025_RS10500	COG0697	spore germination
CG025_RS10535	COG2885	chlorophyll binding
CG025_RS10565	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CG025_RS10570	COG3384	dioxygenase
CG025_RS10585	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CG025_RS10590	COG3474	cytochrome
CG025_RS10600	COG1595	DNA-templated transcription, initiation
CG025_RS10615	COG2204	response regulator
CG025_RS10655	COG4964	Belongs to the GSP D family
CG025_RS10710	COG1846	Transcriptional regulator
CG025_RS10715	COG4172	Belongs to the ABC transporter superfamily
CG025_RS10720	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CG025_RS10725	COG0601	transmembrane transport
CG025_RS10730	COG0747	negative chemotaxis
CG025_RS10740	COG0598	Magnesium transport protein CorA
CG025_RS10745	COG0210	DNA helicase
CG025_RS10760	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CG025_RS10765	COG1012	belongs to the aldehyde dehydrogenase family
CG025_RS10770	COG0483	inositol monophosphate 1-phosphatase activity
CG025_RS10775	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CG025_RS10785	COG1045	serine acetyltransferase
CG025_RS10790	COG0166	Belongs to the GPI family
CG025_RS10805	COG2197	response regulator
CG025_RS10810	COG1846	Transcriptional regulator
CG025_RS10830	COG0726	polysaccharide deacetylase
CG025_RS10830	COG1649	PFAM Uncharacterised BCR, COG1649
CG025_RS10835	COG1215	transferase activity, transferring glycosyl groups
CG025_RS10845	COG1902	pentaerythritol trinitrate reductase activity
CG025_RS10870	COG0251	oxidation-reduction process
CG025_RS10880	COG1832	CoA-binding protein
CG025_RS10885	COG1414	Transcriptional regulator
CG025_RS10890	COG1902	pentaerythritol trinitrate reductase activity
CG025_RS10890	COG0446	pyridine nucleotide-disulphide oxidoreductase
CG025_RS10900	COG3842	ATPase activity
CG025_RS10925	COG0583	DNA-binding transcription factor activity
CG025_RS10935	COG1028	Short-chain dehydrogenase reductase Sdr
CG025_RS10940	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
CG025_RS10945	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CG025_RS10960	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CG025_RS10960	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CG025_RS10965	COG1250	3-hydroxyacyl-CoA dehydrogenase
CG025_RS10990	COG0527	aspartate kinase activity
CG025_RS10995	COG0037	tRNA processing
CG025_RS11005	COG0825	malonyl-CoA metabolic process
CG025_RS11015	COG0215	cysteine-tRNA ligase activity
CG025_RS11030	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CG025_RS11035	COG1968	undecaprenyl-diphosphatase activity
CG025_RS11040	COG1253	flavin adenine dinucleotide binding
CG025_RS11045	COG0483	inositol monophosphate 1-phosphatase activity
CG025_RS11065	COG0668	transmembrane transport
CG025_RS11115	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CG025_RS11130	COG2831	hemolysin activation secretion protein
CG025_RS11135	COG3539	Fimbrial protein
CG025_RS11140	COG3188	usher protein
CG025_RS11145	COG3121	Chaperone
CG025_RS11155	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CG025_RS11155	COG3210	domain, Protein
CG025_RS11155	COG3064	Membrane
CG025_RS11160	COG2197	response regulator
CG025_RS11165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG025_RS11165	COG2205	protein histidine kinase activity
CG025_RS11175	COG4336	lyase activity
CG025_RS11225	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CG025_RS11235	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CG025_RS11235	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CG025_RS11245	COG0028	Belongs to the TPP enzyme family
CG025_RS11260	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CG025_RS11270	COG1126	abc transporter atp-binding protein
CG025_RS11280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG025_RS11295	COG0084	hydrolase, TatD family'
CG025_RS11300	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CG025_RS11305	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CG025_RS11310	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CG025_RS11330	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CG025_RS11335	COG1959	2 iron, 2 sulfur cluster binding
CG025_RS11340	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CG025_RS11340	COG1017	nitric oxide dioxygenase activity
CG025_RS11375	COG0488	(ABC) transporter
CG025_RS11380	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CG025_RS11395	COG1024	Enoyl-CoA hydratase
CG025_RS11400	COG1619	proteins homologs of microcin C7 resistance protein MccF
CG025_RS11405	COG0590	tRNA wobble adenosine to inosine editing
CG025_RS11430	COG2212	antiporter activity
CG025_RS11435	COG1863	multisubunit Na H antiporter MnhE subunit
CG025_RS11440	COG0651	ATP synthesis coupled electron transport
CG025_RS11445	COG1006	Multisubunit Na H antiporter MnhC subunit
CG025_RS11450	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CG025_RS11450	COG2111	Na H antiporter
CG025_RS11470	COG0583	DNA-binding transcription factor activity
CG025_RS11475	COG1028	Short-chain dehydrogenase reductase Sdr
CG025_RS11505	COG0431	NADPH-dependent FMN reductase
CG025_RS11550	COG1028	Short-chain dehydrogenase reductase Sdr
CG025_RS11555	COG0179	Fumarylacetoacetate (FAA) hydrolase
CG025_RS11585	COG0625	glutathione transferase activity
CG025_RS11595	COG2944	sequence-specific DNA binding
CG025_RS11605	COG2197	response regulator
CG025_RS11630	COG3119	arylsulfatase activity
CG025_RS11665	COG0714	Associated with various cellular activities
CG025_RS11685	COG1028	Short-chain dehydrogenase reductase Sdr
CG025_RS11690	COG0861	Integral membrane protein TerC family
CG025_RS11735	COG0300	oxidoreductase activity
CG025_RS11760	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CG025_RS11775	COG0438	transferase activity, transferring glycosyl groups
CG025_RS11795	COG0463	Glycosyl transferase, family 2
CG025_RS11815	COG0783	Belongs to the Dps family
CG025_RS11830	COG0583	DNA-binding transcription factor activity
CG025_RS11835	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CG025_RS11850	COG0656	L-ascorbic acid biosynthetic process
CG025_RS11860	COG0583	DNA-binding transcription factor activity
CG025_RS11870	COG1840	ABC-type Fe3 transport system, periplasmic component
CG025_RS11875	COG1178	ABC-type Fe3 transport system permease component
CG025_RS11880	COG3842	ATPase activity
CG025_RS11890	COG1741	Belongs to the pirin family
CG025_RS11895	COG1741	Belongs to the pirin family
CG025_RS11900	COG0583	DNA-binding transcription factor activity
CG025_RS11905	COG2204	response regulator
CG025_RS11915	COG0174	glutamine synthetase
CG025_RS11920	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CG025_RS11930	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CG025_RS11935	COG2200	EAL domain
CG025_RS11935	COG2199	diguanylate cyclase activity
CG025_RS11955	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CG025_RS11960	COG1561	YicC-like family, N-terminal region
CG025_RS11980	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CG025_RS11985	COG0791	NLP P60 protein
CG025_RS11990	COG1028	Short-chain dehydrogenase reductase Sdr
CG025_RS11995	COG2863	cytochrome
CG025_RS12000	COG3258	Cytochrome c
CG025_RS12005	COG0194	GDP metabolic process
CG025_RS12010	COG1758	RNA polymerase activity
CG025_RS12015	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CG025_RS12020	COG1126	abc transporter atp-binding protein
CG025_RS12025	COG0765	amino acid transport
CG025_RS12030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG025_RS12045	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CG025_RS12050	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CG025_RS12055	COG3539	Fimbrial protein
CG025_RS12060	COG2850	peptidyl-arginine hydroxylation
CG025_RS12065	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CG025_RS12070	COG3360	Dodecin
CG025_RS12115	COG0009	L-threonylcarbamoyladenylate synthase
CG025_RS12120	COG2321	neutral zinc metallopeptidase
CG025_RS12140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CG025_RS12145	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CG025_RS12150	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CG025_RS12160	COG1074	ATP-dependent DNA helicase activity
CG025_RS12170	COG2814	Major facilitator Superfamily
CG025_RS12180	COG1686	Belongs to the peptidase S11 family
CG025_RS12195	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CG025_RS12200	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CG025_RS12205	COG4974	Belongs to the 'phage' integrase family
CG025_RS12210	COG0583	DNA-binding transcription factor activity
CG025_RS12215	COG0028	Belongs to the TPP enzyme family
CG025_RS12230	COG0028	Belongs to the TPP enzyme family
CG025_RS12235	COG1126	abc transporter atp-binding protein
CG025_RS12240	COG0765	amino acid transport
CG025_RS12255	COG1414	Transcriptional regulator
CG025_RS12260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG025_RS12265	COG0009	L-threonylcarbamoyladenylate synthase
CG025_RS12270	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CG025_RS12275	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CG025_RS12280	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CG025_RS12290	COG2944	sequence-specific DNA binding
CG025_RS12300	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CG025_RS12355	COG1126	abc transporter atp-binding protein
CG025_RS12360	COG0765	amino acid transport
CG025_RS12365	COG0765	amino acid transport
CG025_RS12370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG025_RS12380	COG2423	ornithine cyclodeaminase activity
CG025_RS12395	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CG025_RS12400	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CG025_RS12410	COG0189	ligase activity
CG025_RS12415	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CG025_RS12420	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CG025_RS12425	COG2197	response regulator
CG025_RS12465	COG3022	response to hydroperoxide
CG025_RS12475	COG1028	Short-chain dehydrogenase reductase Sdr
CG025_RS12490	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CG025_RS12520	COG2814	Major facilitator Superfamily
CG025_RS12540	COG3706	GGDEF domain
CG025_RS12565	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CG025_RS12570	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CG025_RS12575	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CG025_RS12580	COG1674	ftsk spoiiie
CG025_RS12585	COG0492	ferredoxin-NADP+ reductase activity
CG025_RS12590	COG1193	negative regulation of DNA recombination
CG025_RS12605	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CG025_RS12620	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CG025_RS12625	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CG025_RS12630	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CG025_RS12640	COG0745	RESPONSE REGULATOR receiver
CG025_RS12685	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CG025_RS12705	COG0612	Peptidase, M16
CG025_RS12715	COG0443	Heat shock 70 kDa protein
CG025_RS12725	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CG025_RS12735	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CG025_RS12740	COG1420	regulation of RNA biosynthetic process
CG025_RS12745	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CG025_RS12750	COG0497	DNA recombination
CG025_RS12755	COG0735	belongs to the Fur family
CG025_RS12760	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CG025_RS12765	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CG025_RS12770	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CG025_RS12805	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CG025_RS12805	COG0446	pyridine nucleotide-disulphide oxidoreductase
CG025_RS12810	COG4311	Sarcosine oxidase, delta subunit
CG025_RS12815	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CG025_RS12825	COG0583	DNA-binding transcription factor activity
CG025_RS12835	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CG025_RS12860	COG4964	Belongs to the GSP D family
CG025_RS12920	COG0181	hydroxymethylbilane synthase activity
CG025_RS12925	COG0861	Integral membrane protein TerC family
CG025_RS12930	COG0861	Integral membrane protein TerC family
CG025_RS12935	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CG025_RS12940	COG0045	succinate-CoA ligase (ADP-forming) activity
CG025_RS12950	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CG025_RS12960	COG2137	regulation of response to DNA damage stimulus
CG025_RS12965	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CG025_RS12985	COG1250	3-hydroxyacyl-CoA dehydrogenase
CG025_RS12985	COG1024	Enoyl-CoA hydratase
CG025_RS12990	COG3842	ATPase activity
CG025_RS13005	COG1028	Short-chain dehydrogenase reductase Sdr
CG025_RS13025	COG0583	DNA-binding transcription factor activity
CG025_RS13030	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CG025_RS13040	COG2974	May be involved in recombination
CG025_RS13045	COG0540	Belongs to the ATCase OTCase family
CG025_RS13110	COG0776	regulation of translation
CG025_RS13115	COG0072	phenylalanine-tRNA ligase activity
CG025_RS13115	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CG025_RS13120	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CG025_RS13125	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CG025_RS13130	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CG025_RS13140	COG0756	dUTP diphosphatase activity
CG025_RS13150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CG025_RS13165	COG0500	methyltransferase
CG025_RS13180	COG0586	Pfam SNARE associated Golgi protein
CG025_RS13210	COG1609	Transcriptional regulator
CG025_RS13215	COG4172	Belongs to the ABC transporter superfamily
CG025_RS13220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CG025_RS13225	COG0601	transmembrane transport
CG025_RS13230	COG0747	negative chemotaxis
CG025_RS13245	COG1280	lysine exporter protein (LysE YggA)
CG025_RS13260	COG2814	Major facilitator Superfamily
CG025_RS13290	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CG025_RS13310	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CG025_RS13345	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CG025_RS13350	COG1116	anion transmembrane transporter activity
CG025_RS13360	COG1228	amidohydrolase
CG025_RS13375	COG0477	Major facilitator Superfamily
CG025_RS13385	COG3550	peptidyl-serine autophosphorylation
CG025_RS13400	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CG025_RS13400	COG0519	Catalyzes the synthesis of GMP from XMP
CG025_RS13445	COG0420	3'-5' exonuclease activity
CG025_RS13450	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CG025_RS13480	COG0395	ABC-type sugar transport system, permease component
CG025_RS13490	COG3842	ATPase activity
CG025_RS13515	COG3181	Tripartite tricarboxylate transporter family receptor
CG025_RS13550	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CG025_RS13575	COG0602	queuosine metabolic process
CG025_RS13580	COG0720	synthase
CG025_RS13585	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CG025_RS13590	COG0235	Class ii aldolase
CG025_RS13620	COG3210	domain, Protein
CG025_RS13620	COG3064	Membrane
CG025_RS13620	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CG025_RS13625	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CG025_RS13625	COG0047	phosphoribosylformylglycinamidine synthase activity
CG025_RS13630	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CG025_RS13635	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CG025_RS13635	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CG025_RS13640	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CG025_RS13660	COG3539	Fimbrial protein
CG025_RS13670	COG2050	protein possibly involved in aromatic compounds catabolism
CG025_RS13675	COG1024	Enoyl-CoA hydratase
CG025_RS13680	COG1012	belongs to the aldehyde dehydrogenase family
CG025_RS13700	COG2151	metal-sulfur cluster biosynthetic enzyme
CG025_RS13705	COG3396	Phenylacetate-CoA oxygenase
CG025_RS13710	COG3460	Phenylacetate-CoA oxygenase
CG025_RS13715	COG3396	Phenylacetate-CoA oxygenase
CG025_RS13720	COG3327	negative regulation of DNA-templated transcription, initiation
CG025_RS13730	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CG025_RS13735	COG0501	Belongs to the peptidase M48B family
CG025_RS13740	COG1162	GTPase activity
CG025_RS13755	COG0601	transmembrane transport
CG025_RS13760	COG0747	negative chemotaxis
CG025_RS13805	COG0668	transmembrane transport
CG025_RS13810	COG0165	Argininosuccinate lyase
CG025_RS13830	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CG025_RS13835	COG0303	'Molybdopterin
CG025_RS13840	COG0521	Mo-molybdopterin cofactor biosynthetic process
CG025_RS13855	COG0315	cyclic pyranopterin monophosphate synthase activity
CG025_RS13865	COG0412	Dienelactone hydrolase
CG025_RS13875	COG0678	peroxiredoxin activity
CG025_RS13885	COG0697	spore germination
CG025_RS13890	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CG025_RS13915	COG0789	Transcriptional regulator
CG025_RS13935	COG1028	Short-chain dehydrogenase reductase Sdr
CG025_RS13945	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CG025_RS13950	COG1845	cytochrome c oxidase, subunit III
CG025_RS13955	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CG025_RS13965	COG0477	Major facilitator Superfamily
CG025_RS14000	COG1309	transcriptional regulator
CG025_RS14005	COG2271	Major facilitator Superfamily
CG025_RS14040	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CG025_RS14040	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CG025_RS14040	COG0506	proline dehydrogenase activity
CG025_RS14050	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CG025_RS14050	COG3008	intermembrane lipid transfer
CG025_RS14055	COG2995	paraquat-inducible protein a
CG025_RS14060	COG0542	response to heat
CG025_RS14065	COG4953	penicillin-binding protein 1C
CG025_RS14075	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CG025_RS14080	COG1278	Cold shock
CG025_RS14090	COG0183	Belongs to the thiolase family
CG025_RS14095	COG0038	chloride channel
CG025_RS14100	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CG025_RS14105	COG1570	exodeoxyribonuclease VII activity
CG025_RS14115	COG0811	peptide transport
CG025_RS14120	COG0848	biopolymer transport protein
CG025_RS14125	COG1663	tetraacyldisaccharide 4'-kinase activity
CG025_RS14130	COG2835	tetraacyldisaccharide 4'-kinase activity
CG025_RS14135	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CG025_RS14140	COG0563	adenylate kinase activity
CG025_RS14150	COG0728	peptidoglycan biosynthetic process
CG025_RS14160	COG0268	Binds directly to 16S ribosomal RNA
CG025_RS14195	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CG025_RS14220	COG0436	Aminotransferase
CG025_RS14225	COG3737	Protein of unknown function (DUF498/DUF598)
CG025_RS14230	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CG025_RS14235	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CG025_RS14240	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CG025_RS14250	COG0305	Participates in initiation and elongation during chromosome replication
CG025_RS14260	COG0359	binds to the 23S rRNA
CG025_RS14265	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CG025_RS14270	COG2965	DNA replication, synthesis of RNA primer
CG025_RS14275	COG0360	Binds together with S18 to 16S ribosomal RNA
CG025_RS14280	COG1469	GTP cyclohydrolase I activity
CG025_RS14285	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CG025_RS14290	COG0142	geranyltranstransferase activity
CG025_RS14295	COG1722	exodeoxyribonuclease VII activity
CG025_RS14305	COG3181	Tripartite tricarboxylate transporter family receptor
CG025_RS14325	COG2239	Acts as a magnesium transporter
CG025_RS14335	COG2855	membrane
CG025_RS14345	COG1473	amidohydrolase
CG025_RS14350	COG0318	PFAM AMP-dependent synthetase and ligase
CG025_RS14375	COG1501	Belongs to the glycosyl hydrolase 31 family
CG025_RS14380	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CG025_RS14385	COG2011	ABC-type metal ion transport system permease component
CG025_RS14405	COG1454	alcohol dehydrogenase
CG025_RS14435	COG2186	Transcriptional regulator
CG025_RS14440	COG3181	Tripartite tricarboxylate transporter family receptor
CG025_RS14460	COG1175	transmembrane transport
CG025_RS14465	COG0395	ABC-type sugar transport system, permease component
CG025_RS14470	COG3842	ATPase activity
CG025_RS14485	COG1653	transport
CG025_RS14505	COG2818	Glycosylase
CG025_RS14510	COG2982	Protein involved in outer membrane biogenesis
CG025_RS14520	COG1309	transcriptional regulator
CG025_RS14525	COG1028	Short-chain dehydrogenase reductase Sdr
CG025_RS14585	COG0583	DNA-binding transcription factor activity
CG025_RS14590	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CG025_RS14595	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CG025_RS14610	COG1028	Short-chain dehydrogenase reductase Sdr
CG025_RS14615	COG0477	Major facilitator Superfamily
CG025_RS14625	COG0583	DNA-binding transcription factor activity
CG025_RS14630	COG1448	Aminotransferase
CG025_RS14635	COG1418	mRNA catabolic process
CG025_RS14660	COG1063	alcohol dehydrogenase
CG025_RS14680	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CG025_RS14690	COG0318	PFAM AMP-dependent synthetase and ligase
CG025_RS14700	COG1522	sequence-specific DNA binding
CG025_RS14705	COG3181	Tripartite tricarboxylate transporter family receptor
CG025_RS14710	COG0307	riboflavin synthase, alpha
CG025_RS14715	COG0154	amidase activity
CG025_RS14735	COG2807	transmembrane transport
CG025_RS14740	COG0590	tRNA wobble adenosine to inosine editing
CG025_RS14750	COG0583	DNA-binding transcription factor activity
CG025_RS14785	COG0559	Belongs to the binding-protein-dependent transport system permease family
CG025_RS14790	COG0251	oxidation-reduction process
CG025_RS14795	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CG025_RS14805	COG1414	Transcriptional regulator
CG025_RS14810	COG1028	Short-chain dehydrogenase reductase Sdr
CG025_RS14825	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CG025_RS14840	COG1024	Enoyl-CoA hydratase
CG025_RS14845	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CG025_RS14850	COG0154	amidase activity
CG025_RS14890	COG3909	cytochrome
CG025_RS14895	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CG025_RS14900	COG0625	glutathione transferase activity
CG025_RS14905	COG0730	response to heat
CG025_RS14910	COG0482	sulfurtransferase activity
CG025_RS14915	COG0583	DNA-binding transcription factor activity
CG025_RS14955	COG2819	hydrolase of the alpha beta superfamily
CG025_RS14960	COG0247	lactate metabolic process
CG025_RS14965	COG0277	FAD linked oxidase domain protein
CG025_RS14970	COG0277	FAD linked oxidase domain protein
CG025_RS14975	COG0277	FAD linked oxidase domain protein
CG025_RS14980	COG3064	Membrane
CG025_RS14980	COG3210	domain, Protein
CG025_RS14980	COG3210	domain, Protein
CG025_RS14980	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CG025_RS14980	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CG025_RS14980	COG3064	Membrane
CG025_RS14985	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CG025_RS14990	COG0312	modulator of DNA gyrase
CG025_RS15025	COG1666	GTP binding
CG025_RS15070	COG3220	belongs to the UPF0276 family
CG025_RS15090	COG0640	Transcriptional regulator
CG025_RS15095	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CG025_RS15100	COG1845	cytochrome c oxidase, subunit III
CG025_RS15105	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CG025_RS15115	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CG025_RS15150	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CG025_RS15155	COG0583	DNA-binding transcription factor activity
CG025_RS15190	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CG025_RS15190	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CG025_RS15205	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CG025_RS15210	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CG025_RS15220	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CG025_RS15235	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CG025_RS15240	COG0316	Belongs to the HesB IscA family
CG025_RS15250	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CG025_RS15255	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CG025_RS15260	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CG025_RS15265	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CG025_RS15270	COG0312	modulator of DNA gyrase
CG025_RS15275	COG3028	Belongs to the UPF0307 family
CG025_RS15290	COG1116	anion transmembrane transporter activity
CG025_RS15295	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CG025_RS15300	COG1335	isochorismatase
CG025_RS15305	COG0346	lactoylglutathione lyase activity
CG025_RS15310	COG0513	Belongs to the DEAD box helicase family
CG025_RS15315	COG3069	C4-dicarboxylate transmembrane transporter activity
CG025_RS15320	COG1802	Transcriptional regulator
CG025_RS15335	COG1042	CoA-binding domain protein
CG025_RS15335	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CG025_RS15335	COG0045	succinate-CoA ligase (ADP-forming) activity
CG025_RS15340	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CG025_RS15355	COG1522	sequence-specific DNA binding
CG025_RS15390	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CG025_RS15395	COG1696	Membrane protein involved in D-alanine export
CG025_RS15420	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CG025_RS15435	COG0439	Biotin carboxylase
CG025_RS15440	COG0511	ligase activity, forming carbon-carbon bonds
CG025_RS15445	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CG025_RS15450	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CG025_RS15455	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CG025_RS15460	COG3150	esterase
CG025_RS15465	COG0557	exoribonuclease II activity
CG025_RS15475	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CG025_RS15495	COG1522	sequence-specific DNA binding
CG025_RS15500	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CG025_RS15505	COG1028	Short-chain dehydrogenase reductase Sdr
CG025_RS15525	COG0653	protein targeting
CG025_RS15530	COG0739	heme binding
CG025_RS15540	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CG025_RS15545	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CG025_RS15555	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CG025_RS15560	COG1181	Belongs to the D-alanine--D-alanine ligase family
CG025_RS15565	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CG025_RS15570	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CG025_RS15580	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CG025_RS15585	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CG025_RS15590	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CG025_RS15600	COG3116	cell division
CG025_RS15605	COG0275	rRNA processing
CG025_RS15610	COG2001	Belongs to the MraZ family
CG025_RS15620	COG0488	(ABC) transporter
CG025_RS15625	COG0418	dihydroorotase activity
CG025_RS15630	COG1473	amidohydrolase
CG025_RS15680	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CG025_RS15685	COG4654	Cytochrome c, class I
CG025_RS15690	COG0129	dihydroxy-acid dehydratase activity
CG025_RS15695	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CG025_RS15755	COG2084	Dehydrogenase
CG025_RS15775	COG2096	Adenosyltransferase
CG025_RS15790	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CG025_RS15795	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CG025_RS15805	COG0523	cobalamin synthesis protein
CG025_RS15810	COG0735	belongs to the Fur family
CG025_RS15825	COG0803	Belongs to the bacterial solute-binding protein 9 family
CG025_RS15835	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CG025_RS15845	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CG025_RS15855	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CG025_RS15860	COG1560	Kdo2-lipid A biosynthetic process
CG025_RS15870	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CG025_RS15885	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CG025_RS15890	COG1950	PFAM Membrane protein of
CG025_RS15905	COG0583	DNA-binding transcription factor activity
CG025_RS15915	COG0477	Major facilitator Superfamily
CG025_RS15930	COG0617	tRNA 3'-terminal CCA addition
CG025_RS15940	COG0513	Belongs to the DEAD box helicase family
CG025_RS15945	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CG025_RS15955	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CG025_RS15960	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CG025_RS16035	COG0405	Gamma-glutamyltransferase
CG025_RS16045	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CG025_RS16075	COG1309	transcriptional regulator
CG025_RS16090	COG0745	RESPONSE REGULATOR receiver
CG025_RS16140	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CG025_RS16165	COG0582	viral genome integration into host DNA
CG025_RS16170	COG0012	GTP binding
CG025_RS16180	COG0193	aminoacyl-tRNA hydrolase activity
CG025_RS16185	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CG025_RS16190	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CG025_RS16200	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CG025_RS16205	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CG025_RS16215	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CG025_RS16240	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CG025_RS16250	COG1368	sulfuric ester hydrolase activity
CG025_RS16255	COG0642	Histidine kinase
CG025_RS16260	COG0745	RESPONSE REGULATOR receiver
CG025_RS16265	COG0277	FAD linked oxidase domain protein
CG025_RS16280	COG0166	Belongs to the GPI family
CG025_RS16285	COG0438	transferase activity, transferring glycosyl groups
CG025_RS16290	COG0438	transferase activity, transferring glycosyl groups
CG025_RS16305	COG0438	transferase activity, transferring glycosyl groups
CG025_RS16320	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CG025_RS16325	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CG025_RS16330	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
CG025_RS16340	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CG025_RS16350	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CG025_RS16355	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CG025_RS16365	COG0747	negative chemotaxis
CG025_RS16370	COG0601	transmembrane transport
CG025_RS16375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CG025_RS16395	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CG025_RS16400	COG0830	nickel cation binding
CG025_RS16410	COG0804	urea catabolic process
CG025_RS16415	COG0832	Belongs to the urease beta subunit family
CG025_RS16425	COG0831	urea catabolic process
CG025_RS16430	COG0829	nickel cation binding
CG025_RS16460	COG2188	Transcriptional regulator
CG025_RS16485	COG2719	SpoVR family
CG025_RS16490	COG2718	Belongs to the UPF0229 family
CG025_RS16510	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CG025_RS16525	COG1960	acyl-CoA dehydrogenase activity
CG025_RS16575	COG2030	dehydratase
CG025_RS16625	COG0328	RNA-DNA hybrid ribonuclease activity
CG025_RS16630	COG2226	methyltransferase
CG025_RS16635	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CG025_RS16640	COG1388	LysM domain
CG025_RS16640	COG0741	lytic transglycosylase activity
CG025_RS16660	COG2979	Protein of unknown function (DUF533)
CG025_RS16695	COG1271	oxidase subunit
CG025_RS16700	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CG025_RS16705	COG0850	regulation of cytokinetic process
CG025_RS16710	COG2894	cell division
CG025_RS16715	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CG025_RS16750	COG0601	transmembrane transport
CG025_RS16760	COG1215	transferase activity, transferring glycosyl groups
CG025_RS16775	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CG025_RS16785	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CG025_RS16805	COG0318	PFAM AMP-dependent synthetase and ligase
CG025_RS16810	COG2188	Transcriptional regulator
CG025_RS16815	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CG025_RS16820	COG2814	Major facilitator Superfamily
CG025_RS16830	COG0259	pyridoxamine-phosphate oxidase activity
CG025_RS16835	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CG025_RS16850	COG0583	DNA-binding transcription factor activity
CG025_RS16875	COG0134	indole-3-glycerol-phosphate synthase activity
CG025_RS16880	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CG025_RS16885	COG0512	Glutamine amidotransferase of anthranilate synthase
CG025_RS16895	COG0546	phosphoglycolate phosphatase activity
CG025_RS16900	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CG025_RS16905	COG2967	ApaG domain
CG025_RS16910	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CG025_RS16915	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CG025_RS16920	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CG025_RS16925	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CG025_RS16935	COG0037	tRNA processing
CG025_RS16945	COG3634	alkyl hydroperoxide reductase activity
CG025_RS16950	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CG025_RS16955	COG1024	Enoyl-CoA hydratase
CG025_RS16980	COG0356	it plays a direct role in the translocation of protons across the membrane
CG025_RS16990	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CG025_RS16995	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CG025_RS17000	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CG025_RS17005	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CG025_RS17010	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CG025_RS17015	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CG025_RS17025	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CG025_RS17030	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CG025_RS17035	COG0210	DNA helicase
CG025_RS17045	COG2195	Cleaves the N-terminal amino acid of tripeptides
CG025_RS17055	COG4172	Belongs to the ABC transporter superfamily
CG025_RS17060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CG025_RS17065	COG0601	transmembrane transport
CG025_RS17085	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CG025_RS17090	COG1024	Enoyl-CoA hydratase
CG025_RS17095	COG1024	Enoyl-CoA hydratase
CG025_RS17150	COG2132	Multicopper oxidase
CG025_RS17160	COG1250	3-hydroxyacyl-CoA dehydrogenase
CG025_RS17160	COG1024	Enoyl-CoA hydratase
CG025_RS17170	COG1414	Transcriptional regulator
CG025_RS17180	COG0154	amidase activity
CG025_RS17210	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CG025_RS17215	COG3568	Endonuclease Exonuclease Phosphatase
CG025_RS17220	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CG025_RS17260	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CG025_RS17270	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CG025_RS17285	COG1137	ATPase activity
CG025_RS17300	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CG025_RS17305	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CG025_RS17305	COG2010	Cytochrome c
CG025_RS17315	COG1660	Displays ATPase and GTPase activities
CG025_RS17320	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CG025_RS17355	COG3181	Tripartite tricarboxylate transporter family receptor
CG025_RS17365	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CG025_RS17370	COG2890	protein-(glutamine-N5) methyltransferase activity
CG025_RS17375	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CG025_RS17380	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CG025_RS17430	COG1960	acyl-CoA dehydrogenase activity
CG025_RS17440	COG0183	Belongs to the thiolase family
CG025_RS17445	COG1522	sequence-specific DNA binding
CG025_RS17450	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CG025_RS17470	COG1024	Enoyl-CoA hydratase
CG025_RS17485	COG0604	alcohol dehydrogenase
CG025_RS17505	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CG025_RS17515	COG1960	acyl-CoA dehydrogenase activity
CG025_RS17520	COG1960	acyl-CoA dehydrogenase activity
CG025_RS17525	COG0277	FAD linked oxidase domain protein
CG025_RS17535	COG3181	Tripartite tricarboxylate transporter family receptor
CG025_RS17560	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CG025_RS17570	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CG025_RS17575	COG3181	Tripartite tricarboxylate transporter family receptor
CG025_RS17580	COG1960	acyl-CoA dehydrogenase activity
CG025_RS17600	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CG025_RS17605	COG1024	Enoyl-CoA hydratase
CG025_RS17610	COG1960	acyl-CoA dehydrogenase activity
CG025_RS17630	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CG025_RS17635	COG0022	dehydrogenase e1 component
CG025_RS17640	COG1024	Enoyl-CoA hydratase
CG025_RS17645	COG0508	dehydrogenase complex catalyzes the overall conversion of
CG025_RS17665	COG0683	leucine binding
CG025_RS17670	COG0559	Belongs to the binding-protein-dependent transport system permease family
CG025_RS17675	COG0411	ABC transporter
CG025_RS17685	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CG025_RS17700	COG3181	Tripartite tricarboxylate transporter family receptor
CG025_RS17730	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CG025_RS17735	COG0793	Belongs to the peptidase S41A family
CG025_RS17740	COG4942	peptidase
CG025_RS17745	COG0588	phosphoglycerate mutase activity
CG025_RS17750	COG1054	Belongs to the UPF0176 family
CG025_RS17755	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CG025_RS17760	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CG025_RS17765	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CG025_RS17770	COG3181	Tripartite tricarboxylate transporter family receptor
CG025_RS17785	COG2226	methyltransferase
CG025_RS17790	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CG025_RS17805	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CG025_RS17810	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CG025_RS17835	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CG025_RS17860	COG1335	isochorismatase
CG025_RS17865	COG2309	aminopeptidase activity
CG025_RS17875	COG3473	Maleate cis-trans isomerase
CG025_RS17885	COG2068	MobA-Related Protein
CG025_RS17910	COG2204	response regulator
CG025_RS17915	COG5000	phosphorelay sensor kinase activity
CG025_RS17925	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CG025_RS17925	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CG025_RS17935	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
CG025_RS17970	COG0583	DNA-binding transcription factor activity
CG025_RS17990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CG025_RS17995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG025_RS18010	COG0758	DNA mediated transformation
CG025_RS18015	COG1522	sequence-specific DNA binding
CG025_RS18025	COG0242	peptide deformylase activity
CG025_RS18040	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CG025_RS18050	COG0546	phosphoglycolate phosphatase activity
CG025_RS18070	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CG025_RS18075	COG1942	4-Oxalocrotonate Tautomerase
CG025_RS18080	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CG025_RS18105	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CG025_RS18125	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CG025_RS18130	COG1024	Enoyl-CoA hydratase
CG025_RS18135	COG1414	Transcriptional regulator
CG025_RS18140	COG0318	PFAM AMP-dependent synthetase and ligase
CG025_RS18145	COG3181	Tripartite tricarboxylate transporter family receptor
CG025_RS18190	COG3422	double-strand break repair
CG025_RS18195	COG0330	HflC and HflK could
CG025_RS18205	COG0251	oxidation-reduction process
CG025_RS18255	COG3723	Recombinational DNA repair protein, rece pathway
CG025_RS18290	COG0582	viral genome integration into host DNA
CG025_RS18325	COG0706	membrane insertase activity
CG025_RS18330	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CG025_RS18335	COG0594	ribonuclease P activity
CG025_RS18340	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CG025_RS18345	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CG025_RS18360	COG1414	Transcriptional regulator
CG025_RS18365	COG0154	amidase activity
CG025_RS18380	COG1304	FMN binding
CG025_RS18430	COG0183	Belongs to the thiolase family
CG025_RS18435	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CG025_RS18450	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CG025_RS18455	COG3181	Tripartite tricarboxylate transporter family receptor
CG025_RS18465	COG2358	TRAP transporter, solute receptor (TAXI family
CG025_RS18475	COG1629	transport
CG025_RS18480	COG2922	Belongs to the Smg family
CG025_RS18505	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CG025_RS18510	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CG025_RS18515	COG1028	Short-chain dehydrogenase reductase Sdr
CG025_RS18520	COG1012	belongs to the aldehyde dehydrogenase family
CG025_RS18530	COG0028	Belongs to the TPP enzyme family
CG025_RS18535	COG1522	sequence-specific DNA binding
CG025_RS18540	COG3781	membrane
CG025_RS18550	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CG025_RS18570	COG4206	TonB-dependent receptor
CG025_RS18575	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CG025_RS18580	COG2022	thiamine diphosphate biosynthetic process
CG025_RS18585	COG0351	phosphomethylpyrimidine kinase
CG025_RS18590	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CG025_RS18605	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CG025_RS18615	COG0628	permease
CG025_RS18625	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CG025_RS18640	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CG025_RS18645	COG0049	tRNA binding
CG025_RS18650	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CG025_RS18655	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CG025_RS18660	COG0051	transcription antitermination factor activity, RNA binding
CG025_RS18665	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CG025_RS18670	COG0088	Forms part of the polypeptide exit tunnel
CG025_RS18675	COG0089	rRNA binding
CG025_RS18680	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CG025_RS18685	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CG025_RS18690	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CG025_RS18695	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CG025_RS18700	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CG025_RS18705	COG0255	Belongs to the universal ribosomal protein uL29 family
CG025_RS18710	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CG025_RS18730	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CG025_RS18735	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CG025_RS18740	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CG025_RS18745	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CG025_RS18750	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CG025_RS18755	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CG025_RS18760	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CG025_RS18765	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CG025_RS18770	COG1841	ribosomal large subunit assembly
CG025_RS18775	COG0200	Binds to the 23S rRNA
CG025_RS18780	COG0201	protein transport
CG025_RS18785	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CG025_RS18790	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CG025_RS18795	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CG025_RS18800	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CG025_RS18805	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CG025_RS18810	COG0202	RNA polymerase activity
CG025_RS18815	COG0203	ribosomal protein L17
CG025_RS18820	COG0537	adenosine 5'-monophosphoramidase activity
CG025_RS18825	COG1324	tolerance protein
CG025_RS18830	COG4232	protein-disulfide reductase activity
CG025_RS18845	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CG025_RS18855	COG1333	cytochrome c biogenesis protein
CG025_RS18860	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CG025_RS18875	COG1965	Belongs to the frataxin family
CG025_RS18885	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CG025_RS18890	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CG025_RS18895	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CG025_RS18910	COG2814	Major facilitator Superfamily
CG025_RS18915	COG0629	single-stranded DNA binding
CG025_RS18955	COG0402	S-adenosylhomocysteine deaminase activity
CG025_RS18965	COG0438	transferase activity, transferring glycosyl groups
CG025_RS18985	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CG025_RS19010	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CG025_RS19035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CG025_RS19040	COG1956	GAF domain-containing protein
CG025_RS19045	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CG025_RS19060	COG1652	LysM domain
CG025_RS19075	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CG025_RS19090	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CG025_RS19120	COG3181	Tripartite tricarboxylate transporter family receptor
CG025_RS19135	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CG025_RS19150	COG1024	Enoyl-CoA hydratase
CG025_RS19165	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CG025_RS19170	COG1309	transcriptional regulator
CG025_RS19175	COG2816	NAD+ diphosphatase activity
CG025_RS19180	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CG025_RS19265	COG2814	Major facilitator Superfamily
CG025_RS19270	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CG025_RS19290	COG1999	signal sequence binding
CG025_RS19295	COG0109	protoheme IX farnesyltransferase activity
CG025_RS19335	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CG025_RS19355	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CG025_RS19360	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CG025_RS19370	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CG025_RS19375	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CG025_RS19385	COG0067	glutamate synthase
CG025_RS19385	COG0069	glutamate synthase activity
CG025_RS19385	COG0070	glutamate synthase
CG025_RS19395	COG3047	cAMP biosynthetic process
CG025_RS19405	COG1127	ABC transporter
CG025_RS19410	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CG025_RS19415	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CG025_RS19420	COG2853	Lipoprotein
CG025_RS19435	COG0842	Transport permease protein
CG025_RS19445	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CG025_RS19450	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CG025_RS19455	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CG025_RS19460	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CG025_RS19465	COG0131	Imidazoleglycerol-phosphate dehydratase
CG025_RS19470	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CG025_RS19475	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CG025_RS19480	COG0107	imidazoleglycerol-phosphate synthase activity
CG025_RS19485	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CG025_RS19490	COG0140	phosphoribosyl-ATP diphosphatase activity
CG025_RS19495	COG0537	adenosine 5'-monophosphoramidase activity
CG025_RS19500	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CG025_RS19505	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CG025_RS19520	COG3181	Tripartite tricarboxylate transporter family receptor
CG025_RS19555	COG3702	type iv secretory pathway
CG025_RS19560	COG3451	type IV secretory pathway VirB4
CG025_RS19575	COG3736	Type IV secretory pathway, component VirB8
CG025_RS19580	COG3504	Conjugal transfer protein
CG025_RS19585	COG2948	multi-organism process
CG025_RS19590	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
CG025_RS19600	COG0697	spore germination
CG025_RS19620	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CG025_RS19625	COG0747	negative chemotaxis
CG025_RS19630	COG0601	transmembrane transport
CG025_RS19635	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CG025_RS19650	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CG025_RS19660	COG0494	nUDIX hydrolase
CG025_RS19705	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
CG025_RS19710	COG0237	dephospho-CoA kinase activity
CG025_RS19715	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CG025_RS19730	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CG025_RS19735	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CG025_RS19745	COG0477	Major facilitator Superfamily
CG025_RS19750	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CG025_RS19765	COG1126	abc transporter atp-binding protein
CG025_RS19770	COG0765	amino acid transport
CG025_RS19775	COG4597	amino acid ABC transporter
CG025_RS19780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG025_RS19785	COG2884	Cell division ATP-binding protein ftsE
CG025_RS19790	COG2177	Part of the ABC transporter FtsEX involved in
CG025_RS19795	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CG025_RS19805	COG1194	a g-specific adenine glycosylase
CG025_RS19815	COG2226	methyltransferase
CG025_RS19825	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CG025_RS19830	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CG025_RS19845	COG1024	Enoyl-CoA hydratase
CG025_RS19865	COG1024	Enoyl-CoA hydratase
CG025_RS19870	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CG025_RS19885	COG0753	catalase activity
CG025_RS19890	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CG025_RS19895	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CG025_RS19905	COG2175	clavaminate synthase activity
CG025_RS19910	COG1473	amidohydrolase
CG025_RS19915	COG4608	Belongs to the ABC transporter superfamily
CG025_RS19920	COG0444	Belongs to the ABC transporter superfamily
CG025_RS19935	COG0747	negative chemotaxis
CG025_RS19940	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CG025_RS19975	COG0436	Aminotransferase
CG025_RS19980	COG1278	Cold shock