locus-tag	class	description
XA13_RS00005	COG0445	tRNA wobble uridine modification
XA13_RS00010	COG0357	Ribosomal RNA small subunit methyltransferase G
XA13_RS00015	COG1192	Involved in chromosome partitioning
XA13_RS00025	COG1475	DNA binding
XA13_RS00030	COG0252	asparaginase activity
XA13_RS00055	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
XA13_RS00065	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
XA13_RS00075	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
XA13_RS00080	COG0081	regulation of translation
XA13_RS00085	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
XA13_RS00090	COG0222	ribosome binding
XA13_RS00095	COG0085	RNA polymerase activity
XA13_RS00100	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
XA13_RS00140	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XA13_RS00165	COG1024	Enoyl-CoA hydratase
XA13_RS00185	COG0752	glycyl-tRNA synthetase alpha subunit
XA13_RS00190	COG0751	glycine-tRNA ligase activity
XA13_RS00195	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
XA13_RS00200	COG0204	Acyl-transferase
XA13_RS00215	COG0242	peptide deformylase activity
XA13_RS00250	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
XA13_RS00255	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XA13_RS00260	COG2813	Specifically methylates the guanine in position
XA13_RS00260	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XA13_RS00275	COG2223	nitrite transmembrane transporter activity
XA13_RS00285	COG1794	racemase activity, acting on amino acids and derivatives
XA13_RS00290	COG1126	abc transporter atp-binding protein
XA13_RS00295	COG0765	amino acid transport
XA13_RS00300	COG0765	amino acid transport
XA13_RS00305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XA13_RS00370	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XA13_RS00400	COG0326	Molecular chaperone. Has ATPase activity
XA13_RS00405	COG0625	glutathione transferase activity
XA13_RS00420	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XA13_RS00425	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
XA13_RS00455	COG0438	transferase activity, transferring glycosyl groups
XA13_RS00460	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
XA13_RS00465	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
XA13_RS00495	COG0859	PFAM glycosyl transferase family 9
XA13_RS00510	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
XA13_RS00520	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XA13_RS00525	COG1127	ABC transporter
XA13_RS00545	COG1686	Belongs to the peptidase S11 family
XA13_RS00555	COG2921	Belongs to the UPF0250 family
XA13_RS00560	COG0321	lipoyl(octanoyl) transferase activity
XA13_RS00565	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
XA13_RS00600	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XA13_RS00610	COG0018	arginyl-trna synthetase
XA13_RS00630	COG0395	ABC-type sugar transport system, permease component
XA13_RS00635	COG1175	transmembrane transport
XA13_RS00640	COG1653	transport
XA13_RS00645	COG3842	ATPase activity
XA13_RS00650	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
XA13_RS00660	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
XA13_RS00680	COG1609	Transcriptional regulator
XA13_RS00690	COG0154	amidase activity
XA13_RS00695	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
XA13_RS00705	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
XA13_RS00715	COG0583	DNA-binding transcription factor activity
XA13_RS00730	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
XA13_RS00735	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
XA13_RS00750	COG1802	Transcriptional regulator
XA13_RS00765	COG1024	Enoyl-CoA hydratase
XA13_RS00775	COG3181	Tripartite tricarboxylate transporter family receptor
XA13_RS00790	COG1984	allophanate hydrolase subunit 2
XA13_RS00795	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
XA13_RS00805	COG0583	DNA-binding transcription factor activity
XA13_RS00810	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XA13_RS00820	COG5002	protein histidine kinase activity
XA13_RS00830	COG5002	protein histidine kinase activity
XA13_RS00835	COG0745	RESPONSE REGULATOR receiver
XA13_RS00840	COG2226	methyltransferase
XA13_RS00855	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XA13_RS00875	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
XA13_RS00885	COG0513	Belongs to the DEAD box helicase family
XA13_RS00890	COG1280	lysine exporter protein (LysE YggA)
XA13_RS00895	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
XA13_RS00930	COG1054	Belongs to the UPF0176 family
XA13_RS00935	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XA13_RS00935	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XA13_RS00945	COG0489	protein tyrosine kinase activity
XA13_RS00960	COG0717	Belongs to the dCTP deaminase family
XA13_RS00990	COG2081	HI0933 family
XA13_RS01005	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XA13_RS01015	COG0404	The glycine cleavage system catalyzes the degradation of glycine
XA13_RS01020	COG0509	glycine decarboxylation via glycine cleavage system
XA13_RS01025	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XA13_RS01025	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XA13_RS01065	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XA13_RS01080	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
XA13_RS01090	COG1414	Transcriptional regulator
XA13_RS01095	COG1028	Short-chain dehydrogenase reductase Sdr
XA13_RS01100	COG2031	fatty acid transporter
XA13_RS01105	COG1250	3-hydroxyacyl-CoA dehydrogenase
XA13_RS01115	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
XA13_RS01120	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
XA13_RS01130	COG4257	antibiotic catabolic process
XA13_RS01155	COG1012	belongs to the aldehyde dehydrogenase family
XA13_RS01160	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
XA13_RS01165	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XA13_RS01190	COG1028	Short-chain dehydrogenase reductase Sdr
XA13_RS01200	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XA13_RS01215	COG2188	Transcriptional regulator
XA13_RS01220	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
XA13_RS01245	COG0617	tRNA 3'-terminal CCA addition
XA13_RS01260	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
XA13_RS01265	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
XA13_RS01270	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
XA13_RS01275	COG0586	Pfam SNARE associated Golgi protein
XA13_RS01280	COG0860	N-Acetylmuramoyl-L-alanine amidase
XA13_RS01285	COG0802	atpase or kinase
XA13_RS01290	COG0114	fumarate hydratase activity
XA13_RS01300	COG3181	Tripartite tricarboxylate transporter family receptor
XA13_RS01310	COG0405	Gamma-glutamyltransferase
XA13_RS01315	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XA13_RS01325	COG1960	acyl-CoA dehydrogenase activity
XA13_RS01350	COG1294	oxidase, subunit
XA13_RS01360	COG4988	ABC transporter
XA13_RS01365	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
XA13_RS01370	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
XA13_RS01385	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
XA13_RS01415	COG2969	positive regulation of protein catabolic process
XA13_RS01420	COG0625	glutathione transferase activity
XA13_RS01425	COG2857	Cytochrome c1
XA13_RS01430	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
XA13_RS01435	COG0723	plastoquinol--plastocyanin reductase activity
XA13_RS01440	COG1970	mechanosensitive ion channel activity
XA13_RS01445	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
XA13_RS01460	COG2808	Putative FMN-binding domain
XA13_RS01465	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XA13_RS01470	COG0747	negative chemotaxis
XA13_RS01475	COG0657	acetylesterase activity
XA13_RS01485	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
XA13_RS01490	COG2207	Transcriptional regulator
XA13_RS01495	COG0129	dihydroxy-acid dehydratase activity
XA13_RS01500	COG2814	Major facilitator Superfamily
XA13_RS01505	COG0583	DNA-binding transcription factor activity
XA13_RS01515	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
XA13_RS01585	COG1024	Enoyl-CoA hydratase
XA13_RS01590	COG1960	acyl-CoA dehydrogenase activity
XA13_RS01615	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XA13_RS01620	COG0352	thiamine-phosphate diphosphorylase activity
XA13_RS01635	COG1678	Uncharacterized ACR, COG1678
XA13_RS01640	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
XA13_RS01645	COG0540	Belongs to the ATCase OTCase family
XA13_RS01660	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
XA13_RS01670	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XA13_RS01705	COG1234	tRNA 3'-trailer cleavage
XA13_RS01725	COG3064	Membrane
XA13_RS01755	COG1683	Conserved Protein
XA13_RS01760	COG1120	ATPase activity
XA13_RS01765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XA13_RS01770	COG4558	Periplasmic binding protein
XA13_RS01775	COG3720	iron ion transport
XA13_RS01785	COG3712	iron ion homeostasis
XA13_RS01790	COG1595	DNA-templated transcription, initiation
XA13_RS01825	COG1802	Transcriptional regulator
XA13_RS01835	COG3069	C4-dicarboxylate transmembrane transporter activity
XA13_RS01845	COG1012	belongs to the aldehyde dehydrogenase family
XA13_RS01880	COG2860	membrane
XA13_RS01885	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
XA13_RS01890	COG0708	Exodeoxyribonuclease III
XA13_RS01895	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
XA13_RS01900	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
XA13_RS01905	COG0154	amidase activity
XA13_RS01910	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
XA13_RS01915	COG1077	Cell shape determining protein MreB Mrl
XA13_RS01920	COG1792	Involved in formation and maintenance of cell shape
XA13_RS01930	COG0768	penicillin binding
XA13_RS01935	COG0772	Belongs to the SEDS family
XA13_RS01940	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
XA13_RS01945	COG0471	metal ion transport
XA13_RS01950	COG1309	transcriptional regulator
XA13_RS01960	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
XA13_RS01975	COG2823	Periplasmic or secreted lipoprotein
XA13_RS01980	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
XA13_RS01995	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
XA13_RS02015	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XA13_RS02025	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XA13_RS02045	COG0492	ferredoxin-NADP+ reductase activity
XA13_RS02055	COG3181	Tripartite tricarboxylate transporter family receptor
XA13_RS02060	COG1250	3-hydroxyacyl-CoA dehydrogenase
XA13_RS02060	COG1024	Enoyl-CoA hydratase
XA13_RS02065	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XA13_RS02070	COG0028	Belongs to the TPP enzyme family
XA13_RS02095	COG3181	Tripartite tricarboxylate transporter family receptor
XA13_RS02105	COG0697	spore germination
XA13_RS02135	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
XA13_RS02140	COG0463	Glycosyl transferase, family 2
XA13_RS02160	COG0786	glutamate:sodium symporter activity
XA13_RS02170	COG2031	fatty acid transporter
XA13_RS02185	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XA13_RS02190	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XA13_RS02200	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
XA13_RS02215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XA13_RS02225	COG1285	pathogenesis
XA13_RS02230	COG1253	flavin adenine dinucleotide binding
XA13_RS02235	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XA13_RS02240	COG1024	Enoyl-CoA hydratase
XA13_RS02245	COG3181	Tripartite tricarboxylate transporter family receptor
XA13_RS02250	COG0583	DNA-binding transcription factor activity
XA13_RS02255	COG1960	acyl-CoA dehydrogenase activity
XA13_RS02265	COG0183	Belongs to the thiolase family
XA13_RS02285	COG0583	DNA-binding transcription factor activity
XA13_RS02290	COG1278	Cold shock
XA13_RS02300	COG1802	Transcriptional regulator
XA13_RS02305	COG1012	belongs to the aldehyde dehydrogenase family
XA13_RS02310	COG2031	fatty acid transporter
XA13_RS02315	COG1017	nitric oxide dioxygenase activity
XA13_RS02315	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
XA13_RS02320	COG0251	oxidation-reduction process
XA13_RS02340	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XA13_RS02350	COG0583	DNA-binding transcription factor activity
XA13_RS02355	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XA13_RS02365	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
XA13_RS02370	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
XA13_RS02375	COG0546	phosphoglycolate phosphatase activity
XA13_RS02385	COG1530	ribonuclease E activity
XA13_RS02400	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
XA13_RS02405	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
XA13_RS02410	COG0159	tryptophan synthase activity
XA13_RS02415	COG0133	tryptophan synthase activity
XA13_RS02425	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XA13_RS02430	COG3228	Belongs to the MtfA family
XA13_RS02440	COG0251	oxidation-reduction process
XA13_RS02445	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
XA13_RS02450	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
XA13_RS02465	COG2878	Part of a membrane complex involved in electron transport
XA13_RS02470	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
XA13_RS02505	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XA13_RS02525	COG1268	BioY protein
XA13_RS02530	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
XA13_RS02535	COG1122	ATPase activity
XA13_RS02540	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
XA13_RS02555	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XA13_RS02560	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
XA13_RS02570	COG1196	nuclear chromosome segregation
XA13_RS02575	COG0477	Major facilitator Superfamily
XA13_RS02580	COG1573	uracil-dna glycosylase
XA13_RS02585	COG1214	PFAM Peptidase M22, glycoprotease
XA13_RS02610	COG0450	alkyl hydroperoxide reductase
XA13_RS02615	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XA13_RS02625	COG2223	nitrite transmembrane transporter activity
XA13_RS02635	COG2186	Transcriptional regulator
XA13_RS02655	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XA13_RS02665	COG0583	DNA-binding transcription factor activity
XA13_RS02675	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
XA13_RS02680	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
XA13_RS02685	COG0137	argininosuccinate synthase activity
XA13_RS02690	COG3158	transport of potassium into the cell
XA13_RS02695	COG0642	Histidine kinase
XA13_RS02725	COG0776	regulation of translation
XA13_RS02730	COG3128	pkhd-type hydroxylase
XA13_RS02740	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XA13_RS02745	COG0557	exoribonuclease II activity
XA13_RS02770	COG0679	Auxin Efflux Carrier
XA13_RS02775	COG2391	methyltransferase activity
XA13_RS02780	COG0069	glutamate synthase activity
XA13_RS02790	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XA13_RS02800	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
XA13_RS02805	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XA13_RS02840	COG3706	GGDEF domain
XA13_RS02860	COG1053	succinate dehydrogenase
XA13_RS02865	COG0583	DNA-binding transcription factor activity
XA13_RS02875	COG1053	succinate dehydrogenase
XA13_RS02895	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
XA13_RS02900	COG0459	protein refolding
XA13_RS02905	COG3468	outer membrane autotransporter barrel domain protein
XA13_RS02920	COG1252	NADH dehydrogenase
XA13_RS02925	COG0284	orotidine-5'-phosphate decarboxylase activity
XA13_RS02930	COG1058	Belongs to the CinA family
XA13_RS02930	COG1546	Belongs to the CinA family
XA13_RS02935	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
XA13_RS02945	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XA13_RS02950	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
XA13_RS02985	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
XA13_RS02990	COG3639	organic phosphonate transmembrane transporter activity
XA13_RS02995	COG3639	organic phosphonate transmembrane transporter activity
XA13_RS03015	COG0742	ribosomal rna small subunit methyltransferase
XA13_RS03020	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
XA13_RS03025	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
XA13_RS03030	COG3135	benzoate transporter
XA13_RS03045	COG0640	Transcriptional regulator
XA13_RS03075	COG4172	Belongs to the ABC transporter superfamily
XA13_RS03080	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XA13_RS03085	COG0601	transmembrane transport
XA13_RS03095	COG0281	malic enzyme
XA13_RS03095	COG0280	phosphate acetyltransferase
XA13_RS03155	COG0583	DNA-binding transcription factor activity
XA13_RS03165	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
XA13_RS03170	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
XA13_RS03175	COG0167	dihydroorotate dehydrogenase activity
XA13_RS03195	COG1414	Transcriptional regulator
XA13_RS03200	COG1546	Belongs to the CinA family
XA13_RS03200	COG1058	Belongs to the CinA family
XA13_RS03220	COG0513	Belongs to the DEAD box helicase family
XA13_RS03250	COG0429	hydrolase of the alpha beta-hydrolase fold
XA13_RS03255	COG4783	chaperone-mediated protein folding
XA13_RS03270	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
XA13_RS03295	COG0006	proline dipeptidase activity
XA13_RS03305	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XA13_RS03325	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
XA13_RS03330	COG0632	four-way junction helicase activity
XA13_RS03345	COG2255	four-way junction helicase activity
XA13_RS03350	COG0514	ATP-dependent DNA helicase (RecQ)
XA13_RS03365	COG0288	reversible hydration of carbon dioxide
XA13_RS03370	COG0154	amidase activity
XA13_RS03380	COG4211	Belongs to the binding-protein-dependent transport system permease family
XA13_RS03410	COG1464	Belongs to the NlpA lipoprotein family
XA13_RS03555	COG1196	nuclear chromosome segregation
XA13_RS03625	COG2135	peptidase activity
XA13_RS03640	COG0494	nUDIX hydrolase
XA13_RS03645	COG0442	prolyl-tRNA aminoacylation
XA13_RS03650	COG0824	Thioesterase
XA13_RS03655	COG0811	peptide transport
XA13_RS03660	COG0848	biopolymer transport protein
XA13_RS03670	COG0823	Involved in the tonB-independent uptake of proteins
XA13_RS03685	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XA13_RS03690	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
XA13_RS03725	COG0700	Nucleoside recognition
XA13_RS03730	COG0469	pyruvate kinase activity
XA13_RS03735	COG1929	Belongs to the glycerate kinase type-1 family
XA13_RS03740	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
XA13_RS03745	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XA13_RS03750	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
XA13_RS03760	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
XA13_RS03770	COG2154	pterin-4-alpha-carbinolamine dehydratase
XA13_RS03795	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
XA13_RS03800	COG0154	amidase activity
XA13_RS03810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XA13_RS03815	COG0601	transmembrane transport
XA13_RS03820	COG0747	negative chemotaxis
XA13_RS03840	COG0019	diaminopimelate decarboxylase activity
XA13_RS03855	COG2353	YceI-like domain
XA13_RS03860	COG4774	siderophore transport
XA13_RS03865	COG3712	iron ion homeostasis
XA13_RS03905	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
XA13_RS03910	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
XA13_RS03915	COG0211	Belongs to the bacterial ribosomal protein bL27 family
XA13_RS03920	COG0261	This protein binds to 23S rRNA in the presence of protein L20
XA13_RS03930	COG0142	geranyltranstransferase activity
XA13_RS03940	COG0583	DNA-binding transcription factor activity
XA13_RS03950	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
XA13_RS03955	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XA13_RS03970	COG2994	toxin metabolic process
XA13_RS03980	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
XA13_RS03985	COG2274	protein secretion by the type I secretion system
XA13_RS03990	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XA13_RS03995	COG1538	Outer membrane efflux protein
XA13_RS04010	COG0765	amino acid transport
XA13_RS04015	COG0765	amino acid transport
XA13_RS04020	COG1126	abc transporter atp-binding protein
XA13_RS04040	COG1028	Short-chain dehydrogenase reductase Sdr
XA13_RS04050	COG1802	Transcriptional regulator
XA13_RS04060	COG1802	Transcriptional regulator
XA13_RS04070	COG0318	PFAM AMP-dependent synthetase and ligase
XA13_RS04080	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XA13_RS04100	COG0028	Belongs to the TPP enzyme family
XA13_RS04120	COG0308	aminopeptidase N
XA13_RS04125	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
XA13_RS04135	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
XA13_RS04140	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
XA13_RS04145	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
XA13_RS04150	COG0560	Phosphoserine phosphatase
XA13_RS04155	COG0583	DNA-binding transcription factor activity
XA13_RS04160	COG3181	Tripartite tricarboxylate transporter family receptor
XA13_RS04165	COG0028	Belongs to the TPP enzyme family
XA13_RS04180	COG4774	siderophore transport
XA13_RS04185	COG4774	siderophore transport
XA13_RS04195	COG1007	ATP synthesis coupled electron transport
XA13_RS04210	COG0713	ATP synthesis coupled electron transport
XA13_RS04220	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XA13_RS04225	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
XA13_RS04230	COG1034	ATP synthesis coupled electron transport
XA13_RS04240	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
XA13_RS04245	COG0649	NAD binding
XA13_RS04250	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XA13_RS04255	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XA13_RS04260	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XA13_RS04265	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
XA13_RS04295	COG0671	phosphoesterase, PA-phosphatase related
XA13_RS04305	COG1597	lipid kinase activity
XA13_RS04310	COG0583	DNA-binding transcription factor activity
XA13_RS04315	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
XA13_RS04325	COG1733	regulation of RNA biosynthetic process
XA13_RS04330	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XA13_RS04335	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XA13_RS04350	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
XA13_RS04370	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XA13_RS04390	COG3608	succinylglutamate desuccinylase aspartoacylase
XA13_RS04395	COG0626	cystathionine gamma-synthase activity
XA13_RS04400	COG0583	DNA-binding transcription factor activity
XA13_RS04435	COG3799	methylaspartate ammonia-lyase activity
XA13_RS04445	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
XA13_RS04455	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
XA13_RS04460	COG0149	triose-phosphate isomerase activity
XA13_RS04480	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
XA13_RS04495	COG1185	polyribonucleotide nucleotidyltransferase activity
XA13_RS04500	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
XA13_RS04515	COG1183	phosphatidylcholine synthase activity
XA13_RS04520	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
XA13_RS04525	COG0440	acetolactate synthase activity
XA13_RS04530	COG0028	Belongs to the TPP enzyme family
XA13_RS04545	COG5265	(ABC) transporter
XA13_RS04550	COG0500	methyltransferase
XA13_RS04570	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
XA13_RS04590	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
XA13_RS04600	COG0511	ligase activity, forming carbon-carbon bonds
XA13_RS04625	COG2188	Transcriptional regulator
XA13_RS04630	COG0439	Biotin carboxylase
XA13_RS04635	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XA13_RS04680	COG5265	(ABC) transporter
XA13_RS04690	COG0667	Aldo Keto reductase
XA13_RS04705	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
XA13_RS04745	COG0583	DNA-binding transcription factor activity
XA13_RS04770	COG2814	Major facilitator Superfamily
XA13_RS04780	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XA13_RS04795	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
XA13_RS04805	COG0287	Prephenate dehydrogenase
XA13_RS04810	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
XA13_RS04815	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
XA13_RS04835	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
XA13_RS04840	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
XA13_RS04845	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XA13_RS04850	COG1555	photosystem II stabilization
XA13_RS04850	COG1596	polysaccharide export
XA13_RS04865	COG2951	lytic endotransglycosylase activity
XA13_RS04870	COG0123	including yeast histone deacetylase and acetoin utilization protein
XA13_RS04885	COG1960	acyl-CoA dehydrogenase activity
XA13_RS04890	COG0450	alkyl hydroperoxide reductase
XA13_RS04905	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
XA13_RS04910	COG4208	sulfate ABC transporter
XA13_RS04915	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
XA13_RS04945	COG0335	large ribosomal subunit rRNA binding
XA13_RS04960	COG0667	Aldo Keto reductase
XA13_RS04970	COG2814	Major facilitator Superfamily
XA13_RS04975	COG3161	chorismate lyase activity
XA13_RS04980	COG1187	pseudouridine synthase activity
XA13_RS04990	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XA13_RS05010	COG1999	signal sequence binding
XA13_RS05015	COG0339	signal peptide processing
XA13_RS05020	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
XA13_RS05025	COG4566	intracellular signal transduction
XA13_RS05035	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
XA13_RS05040	COG0508	dehydrogenase complex catalyzes the overall conversion of
XA13_RS05045	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XA13_RS05050	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
XA13_RS05060	COG1385	rRNA (uridine-N3-)-methyltransferase activity
XA13_RS05065	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
XA13_RS05070	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
XA13_RS05075	COG0126	phosphoglycerate kinase activity
XA13_RS05080	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
XA13_RS05085	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
XA13_RS05100	COG0625	glutathione transferase activity
XA13_RS05135	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
XA13_RS05145	COG0521	Mo-molybdopterin cofactor biosynthetic process
XA13_RS05155	COG0739	heme binding
XA13_RS05165	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
XA13_RS05200	COG0745	RESPONSE REGULATOR receiver
XA13_RS05215	COG0840	transmembrane signaling receptor activity
XA13_RS05225	COG2201	protein-glutamate methylesterase activity
XA13_RS05230	COG0745	RESPONSE REGULATOR receiver
XA13_RS05235	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
XA13_RS05260	COG0667	Aldo Keto reductase
XA13_RS05270	COG4535	Mg2 and Co2 transporter CorC
XA13_RS05275	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
XA13_RS05280	COG1702	phosphate starvation-inducible protein PhoH
XA13_RS05285	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XA13_RS05300	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XA13_RS05305	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XA13_RS05310	COG1862	Preprotein translocase
XA13_RS05315	COG0343	queuine tRNA-ribosyltransferase activity
XA13_RS05320	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
XA13_RS05325	COG2027	D-alanyl-D-alanine carboxypeptidase
XA13_RS05330	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
XA13_RS05340	COG3468	outer membrane autotransporter barrel domain protein
XA13_RS05345	COG1648	precorrin-2 dehydrogenase activity
XA13_RS05345	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XA13_RS05370	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
XA13_RS05375	COG0741	lytic transglycosylase activity
XA13_RS05380	COG0436	Aminotransferase
XA13_RS05390	COG0281	malic enzyme
XA13_RS05390	COG0280	phosphate acetyltransferase
XA13_RS05400	COG2732	(Barnase) inhibitor
XA13_RS05415	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
XA13_RS05440	COG0248	Ppx GppA phosphatase
XA13_RS05450	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XA13_RS05460	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
XA13_RS05465	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
XA13_RS05470	COG1534	Rna-binding protein
XA13_RS05500	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XA13_RS05515	COG1295	ribonuclease BN
XA13_RS05525	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
XA13_RS05530	COG0745	RESPONSE REGULATOR receiver
XA13_RS05535	COG2205	protein histidine kinase activity
XA13_RS05570	COG1022	Amp-dependent synthetase and ligase
XA13_RS05585	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
XA13_RS05590	COG1028	Short-chain dehydrogenase reductase Sdr
XA13_RS05600	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
XA13_RS05615	COG1136	(ABC) transporter
XA13_RS05620	COG0084	hydrolase, TatD family'
XA13_RS05650	COG2333	competence protein COMEC
XA13_RS05650	COG0658	competence protein
XA13_RS05660	COG0613	PHP domain protein
XA13_RS05680	COG3539	Fimbrial protein
XA13_RS05685	COG0281	malic enzyme
XA13_RS05685	COG0280	phosphate acetyltransferase
XA13_RS05695	COG1522	sequence-specific DNA binding
XA13_RS05705	COG0567	Dehydrogenase, E1 component
XA13_RS05710	COG0508	dehydrogenase complex catalyzes the overall conversion of
XA13_RS05715	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XA13_RS05720	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
XA13_RS05725	COG1028	Short-chain dehydrogenase reductase Sdr
XA13_RS05730	COG0583	DNA-binding transcription factor activity
XA13_RS05740	COG3181	Tripartite tricarboxylate transporter family receptor
XA13_RS05765	COG0180	Tryptophanyl-tRNA synthetase
XA13_RS05770	COG2183	response to ionizing radiation
XA13_RS05775	COG1199	ATP-dependent helicase activity
XA13_RS05785	COG0564	pseudouridine synthase activity
XA13_RS05795	COG3243	poly(R)-hydroxyalkanoic acid synthase
XA13_RS05800	COG1028	Short-chain dehydrogenase reductase Sdr
XA13_RS05805	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
XA13_RS05820	COG0672	)-iron permease
XA13_RS05860	COG0583	DNA-binding transcription factor activity
XA13_RS05870	COG2814	Major facilitator Superfamily
XA13_RS05885	COG1619	proteins homologs of microcin C7 resistance protein MccF
XA13_RS05900	COG2084	Dehydrogenase
XA13_RS05905	COG3181	Tripartite tricarboxylate transporter family receptor
XA13_RS05930	COG2988	succinylglutamate desuccinylase activity
XA13_RS05960	COG0765	amino acid transport
XA13_RS05965	COG0765	amino acid transport
XA13_RS05970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XA13_RS06005	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XA13_RS06010	COG1595	DNA-templated transcription, initiation
XA13_RS06020	COG3530	Putative quorum-sensing-regulated virulence factor
XA13_RS06025	COG0494	nUDIX hydrolase
XA13_RS06040	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XA13_RS06045	COG0542	response to heat
XA13_RS06060	COG3468	outer membrane autotransporter barrel domain protein
XA13_RS06065	COG3468	outer membrane autotransporter barrel domain protein
XA13_RS06075	COG5441	Belongs to the UPF0261 family
XA13_RS06080	COG5564	TIM-barrel signal transduction protein
XA13_RS06095	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
XA13_RS06110	COG1477	protein flavinylation
XA13_RS06130	COG1131	(ABC) transporter
XA13_RS06135	COG0842	Transport permease protein
XA13_RS06145	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
XA13_RS06150	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
XA13_RS06150	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
XA13_RS06155	COG1562	ergosterol biosynthetic process
XA13_RS06160	COG1562	ergosterol biosynthetic process
XA13_RS06165	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
XA13_RS06170	COG1028	Short-chain dehydrogenase reductase Sdr
XA13_RS06190	COG2304	oxidoreductase activity
XA13_RS06210	COG0534	Mate efflux family protein
XA13_RS06220	COG0254	rRNA binding
XA13_RS06225	COG3483	tryptophan 2,3-dioxygenase activity
XA13_RS06230	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
XA13_RS06235	COG2003	Belongs to the UPF0758 family
XA13_RS06240	COG1047	Peptidyl-prolyl cis-trans
XA13_RS06245	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
XA13_RS06250	COG0625	glutathione transferase activity
XA13_RS06270	COG0523	cobalamin synthesis protein
XA13_RS06280	COG0583	DNA-binding transcription factor activity
XA13_RS06290	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
XA13_RS06295	COG1187	pseudouridine synthase activity
XA13_RS06300	COG0779	Required for maturation of 30S ribosomal subunits
XA13_RS06305	COG2251	uridine kinase activity
XA13_RS06305	COG0195	Participates in both transcription termination and antitermination
XA13_RS06310	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
XA13_RS06315	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
XA13_RS06320	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
XA13_RS06340	COG1611	Belongs to the LOG family
XA13_RS06355	COG0412	Dienelactone hydrolase
XA13_RS06360	COG1283	sodium-dependent phosphate transmembrane transporter activity
XA13_RS06365	COG1760	l-serine dehydratase
XA13_RS06370	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XA13_RS06375	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
XA13_RS06385	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
XA13_RS06410	COG2311	Membrane
XA13_RS06420	COG0697	spore germination
XA13_RS06435	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
XA13_RS06450	COG0559	Belongs to the binding-protein-dependent transport system permease family
XA13_RS06465	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XA13_RS06475	COG1653	transport
XA13_RS06480	COG1175	transmembrane transport
XA13_RS06485	COG0395	ABC-type sugar transport system, permease component
XA13_RS06490	COG3842	ATPase activity
XA13_RS06515	COG2363	Small membrane protein
XA13_RS06530	COG1464	Belongs to the NlpA lipoprotein family
XA13_RS06540	COG0688	phosphatidylethanolamine metabolic process
XA13_RS06565	COG0625	glutathione transferase activity
XA13_RS06570	COG0386	Belongs to the glutathione peroxidase family
XA13_RS06590	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XA13_RS06620	COG2259	Doxx family
XA13_RS06635	COG0667	Aldo Keto reductase
XA13_RS06665	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
XA13_RS06685	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XA13_RS06695	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XA13_RS06735	COG0392	lysyltransferase activity
XA13_RS06750	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XA13_RS06755	COG3568	Endonuclease Exonuclease Phosphatase
XA13_RS06765	COG1695	Transcriptional regulator
XA13_RS06785	COG0583	DNA-binding transcription factor activity
XA13_RS06800	COG1802	Transcriptional regulator
XA13_RS06810	COG3181	Tripartite tricarboxylate transporter family receptor
XA13_RS06820	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XA13_RS06835	COG0066	3-isopropylmalate dehydratase activity
XA13_RS06845	COG3181	Tripartite tricarboxylate transporter family receptor
XA13_RS06850	COG4948	Mandelate Racemase Muconate Lactonizing
XA13_RS06865	COG1126	abc transporter atp-binding protein
XA13_RS06870	COG0765	amino acid transport
XA13_RS06875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XA13_RS06895	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
XA13_RS06920	COG1815	bacterial-type flagellum-dependent cell motility
XA13_RS06925	COG1558	bacterial-type flagellum-dependent cell motility
XA13_RS06935	COG1749	Flagellar hook protein flgE
XA13_RS06950	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
XA13_RS06955	COG1706	bacterial-type flagellum-dependent cell motility
XA13_RS06965	COG1256	bacterial-type flagellum assembly
XA13_RS06975	COG0840	transmembrane signaling receptor activity
XA13_RS06980	COG0840	transmembrane signaling receptor activity
XA13_RS06985	COG0840	transmembrane signaling receptor activity
XA13_RS07005	COG1338	Plays a role in the flagellum-specific transport system
XA13_RS07025	COG1580	Controls the rotational direction of flagella during chemotaxis
XA13_RS07050	COG1157	protein secretion by the type III secretion system
XA13_RS07060	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
XA13_RS07070	COG1677	Flagellar hook-basal body complex protein FliE
XA13_RS07080	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
XA13_RS07115	COG0285	dihydrofolate synthase activity
XA13_RS07145	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
XA13_RS07150	COG0024	Methionine aminopeptidase
XA13_RS07155	COG0052	Belongs to the universal ribosomal protein uS2 family
XA13_RS07160	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
XA13_RS07165	COG0528	UMP kinase activity
XA13_RS07170	COG0233	cytoplasmic translational termination
XA13_RS07175	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
XA13_RS07185	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
XA13_RS07190	COG0750	zinc metalloprotease
XA13_RS07195	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XA13_RS07200	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
XA13_RS07205	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XA13_RS07210	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XA13_RS07220	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XA13_RS07225	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
XA13_RS07230	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XA13_RS07235	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
XA13_RS07245	COG0519	Catalyzes the synthesis of GMP from XMP
XA13_RS07245	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XA13_RS07260	COG0330	HflC and HflK could
XA13_RS07265	COG3706	GGDEF domain
XA13_RS07270	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
XA13_RS07280	COG2867	negative regulation of translational initiation
XA13_RS07290	COG1960	acyl-CoA dehydrogenase activity
XA13_RS07295	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
XA13_RS07325	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
XA13_RS07330	COG0505	Belongs to the CarA family
XA13_RS07335	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
XA13_RS07345	COG0406	alpha-ribazole phosphatase activity
XA13_RS07355	COG3842	ATPase activity
XA13_RS07375	COG5001	Diguanylate cyclase
XA13_RS07380	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
XA13_RS07390	COG1763	Mo-molybdopterin cofactor biosynthetic process
XA13_RS07395	COG0303	'Molybdopterin
XA13_RS07400	COG0746	molybdenum cofactor guanylyltransferase activity
XA13_RS07405	COG0489	protein tyrosine kinase activity
XA13_RS07435	COG0243	molybdopterin cofactor binding
XA13_RS07435	COG3383	formate dehydrogenase (NAD+) activity
XA13_RS07440	COG0437	4 iron, 4 sulfur cluster binding
XA13_RS07470	COG1122	ATPase activity
XA13_RS07480	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
XA13_RS07485	COG0066	3-isopropylmalate dehydratase activity
XA13_RS07490	COG0473	3-isopropylmalate dehydrogenase activity
XA13_RS07495	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
XA13_RS07505	COG0101	tRNA pseudouridine synthase activity
XA13_RS07510	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
XA13_RS07525	COG0135	phosphoribosylanthranilate isomerase activity
XA13_RS07540	COG3022	response to hydroperoxide
XA13_RS07550	COG1289	transmembrane transporter activity
XA13_RS07570	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XA13_RS07580	COG2197	response regulator
XA13_RS07585	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
XA13_RS07590	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
XA13_RS07595	COG0189	ligase activity
XA13_RS07605	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
XA13_RS07610	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XA13_RS07620	COG1764	response to oxidative stress
XA13_RS07625	COG2423	ornithine cyclodeaminase activity
XA13_RS07635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XA13_RS07640	COG0765	amino acid transport
XA13_RS07645	COG0765	amino acid transport
XA13_RS07650	COG1126	abc transporter atp-binding protein
XA13_RS07705	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
XA13_RS07715	COG2944	sequence-specific DNA binding
XA13_RS07725	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
XA13_RS07730	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
XA13_RS07735	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
XA13_RS07740	COG0009	L-threonylcarbamoyladenylate synthase
XA13_RS07745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XA13_RS07750	COG1414	Transcriptional regulator
XA13_RS07765	COG0765	amino acid transport
XA13_RS07770	COG1126	abc transporter atp-binding protein
XA13_RS07775	COG0028	Belongs to the TPP enzyme family
XA13_RS07790	COG0028	Belongs to the TPP enzyme family
XA13_RS07795	COG0583	DNA-binding transcription factor activity
XA13_RS07800	COG4974	Belongs to the 'phage' integrase family
XA13_RS07805	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
XA13_RS07810	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
XA13_RS07825	COG1686	Belongs to the peptidase S11 family
XA13_RS07835	COG2814	Major facilitator Superfamily
XA13_RS07845	COG1074	ATP-dependent DNA helicase activity
XA13_RS07860	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
XA13_RS07865	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
XA13_RS07870	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
XA13_RS07890	COG2321	neutral zinc metallopeptidase
XA13_RS07895	COG0009	L-threonylcarbamoyladenylate synthase
XA13_RS07940	COG3360	Dodecin
XA13_RS07945	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
XA13_RS07950	COG2850	peptidyl-arginine hydroxylation
XA13_RS07955	COG3539	Fimbrial protein
XA13_RS07960	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
XA13_RS07965	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XA13_RS07985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XA13_RS07990	COG0765	amino acid transport
XA13_RS07995	COG1126	abc transporter atp-binding protein
XA13_RS08000	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XA13_RS08005	COG1758	RNA polymerase activity
XA13_RS08010	COG0194	GDP metabolic process
XA13_RS08015	COG3258	Cytochrome c
XA13_RS08020	COG2863	cytochrome
XA13_RS08025	COG1028	Short-chain dehydrogenase reductase Sdr
XA13_RS08030	COG0791	NLP P60 protein
XA13_RS08035	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
XA13_RS08055	COG1561	YicC-like family, N-terminal region
XA13_RS08060	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
XA13_RS08075	COG0840	transmembrane signaling receptor activity
XA13_RS08080	COG2199	diguanylate cyclase activity
XA13_RS08080	COG2200	EAL domain
XA13_RS08085	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
XA13_RS08095	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XA13_RS08100	COG0174	glutamine synthetase
XA13_RS08110	COG2204	response regulator
XA13_RS08115	COG0583	DNA-binding transcription factor activity
XA13_RS08120	COG1741	Belongs to the pirin family
XA13_RS08125	COG1741	Belongs to the pirin family
XA13_RS08135	COG3842	ATPase activity
XA13_RS08140	COG1178	ABC-type Fe3 transport system permease component
XA13_RS08145	COG1840	ABC-type Fe3 transport system, periplasmic component
XA13_RS08155	COG0583	DNA-binding transcription factor activity
XA13_RS08165	COG0656	L-ascorbic acid biosynthetic process
XA13_RS08180	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
XA13_RS08185	COG0583	DNA-binding transcription factor activity
XA13_RS08200	COG0783	Belongs to the Dps family
XA13_RS08220	COG0463	Glycosyl transferase, family 2
XA13_RS08240	COG0438	transferase activity, transferring glycosyl groups
XA13_RS08255	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
XA13_RS08280	COG0300	oxidoreductase activity
XA13_RS08325	COG0861	Integral membrane protein TerC family
XA13_RS08330	COG1028	Short-chain dehydrogenase reductase Sdr
XA13_RS08350	COG0714	Associated with various cellular activities
XA13_RS08385	COG3119	arylsulfatase activity
XA13_RS08410	COG2197	response regulator
XA13_RS08420	COG2944	sequence-specific DNA binding
XA13_RS08425	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
XA13_RS08430	COG0625	glutathione transferase activity
XA13_RS08460	COG0179	Fumarylacetoacetate (FAA) hydrolase
XA13_RS08465	COG1028	Short-chain dehydrogenase reductase Sdr
XA13_RS08510	COG0431	NADPH-dependent FMN reductase
XA13_RS08540	COG1028	Short-chain dehydrogenase reductase Sdr
XA13_RS08545	COG0583	DNA-binding transcription factor activity
XA13_RS08560	COG3181	Tripartite tricarboxylate transporter family receptor
XA13_RS08565	COG2111	Na H antiporter
XA13_RS08565	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XA13_RS08570	COG1006	Multisubunit Na H antiporter MnhC subunit
XA13_RS08575	COG0651	ATP synthesis coupled electron transport
XA13_RS08580	COG1863	multisubunit Na H antiporter MnhE subunit
XA13_RS08585	COG2212	antiporter activity
XA13_RS08610	COG0590	tRNA wobble adenosine to inosine editing
XA13_RS08615	COG1619	proteins homologs of microcin C7 resistance protein MccF
XA13_RS08620	COG1024	Enoyl-CoA hydratase
XA13_RS08635	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
XA13_RS08640	COG0488	(ABC) transporter
XA13_RS08675	COG1017	nitric oxide dioxygenase activity
XA13_RS08675	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
XA13_RS08680	COG1959	2 iron, 2 sulfur cluster binding
XA13_RS08685	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XA13_RS08705	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
XA13_RS08710	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
XA13_RS08715	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
XA13_RS08720	COG0084	hydrolase, TatD family'
XA13_RS08735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XA13_RS08745	COG1126	abc transporter atp-binding protein
XA13_RS08750	COG0010	Belongs to the arginase family
XA13_RS08755	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
XA13_RS08760	COG1012	belongs to the aldehyde dehydrogenase family
XA13_RS08770	COG0028	Belongs to the TPP enzyme family
XA13_RS08780	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
XA13_RS08780	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
XA13_RS08790	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XA13_RS08805	COG3189	MarR family transcriptional regulator
XA13_RS08810	COG2010	Cytochrome c
XA13_RS08835	COG4336	lyase activity
XA13_RS08845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XA13_RS08845	COG2205	protein histidine kinase activity
XA13_RS08850	COG2197	response regulator
XA13_RS08855	COG3210	domain, Protein
XA13_RS08855	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
XA13_RS08855	COG3064	Membrane
XA13_RS08865	COG3121	Chaperone
XA13_RS08870	COG3188	usher protein
XA13_RS08875	COG3539	Fimbrial protein
XA13_RS08880	COG2831	hemolysin activation secretion protein
XA13_RS08895	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XA13_RS08920	COG0583	DNA-binding transcription factor activity
XA13_RS08945	COG0668	transmembrane transport
XA13_RS08965	COG0483	inositol monophosphate 1-phosphatase activity
XA13_RS08970	COG1253	flavin adenine dinucleotide binding
XA13_RS08975	COG1968	undecaprenyl-diphosphatase activity
XA13_RS08980	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XA13_RS08995	COG0215	cysteine-tRNA ligase activity
XA13_RS09005	COG0825	malonyl-CoA metabolic process
XA13_RS09015	COG0037	tRNA processing
XA13_RS09020	COG0527	aspartate kinase activity
XA13_RS09045	COG1250	3-hydroxyacyl-CoA dehydrogenase
XA13_RS09050	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
XA13_RS09050	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
XA13_RS09065	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XA13_RS09070	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
XA13_RS09075	COG1028	Short-chain dehydrogenase reductase Sdr
XA13_RS09085	COG0583	DNA-binding transcription factor activity
XA13_RS09115	COG3842	ATPase activity
XA13_RS09125	COG0446	pyridine nucleotide-disulphide oxidoreductase
XA13_RS09125	COG1902	pentaerythritol trinitrate reductase activity
XA13_RS09130	COG1414	Transcriptional regulator
XA13_RS09135	COG1832	CoA-binding protein
XA13_RS09145	COG0251	oxidation-reduction process
XA13_RS09170	COG1902	pentaerythritol trinitrate reductase activity
XA13_RS09180	COG1215	transferase activity, transferring glycosyl groups
XA13_RS09185	COG0726	polysaccharide deacetylase
XA13_RS09185	COG1649	PFAM Uncharacterised BCR, COG1649
XA13_RS09205	COG1846	Transcriptional regulator
XA13_RS09210	COG2197	response regulator
XA13_RS09225	COG0166	Belongs to the GPI family
XA13_RS09230	COG1045	serine acetyltransferase
XA13_RS09240	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
XA13_RS09245	COG0483	inositol monophosphate 1-phosphatase activity
XA13_RS09250	COG1012	belongs to the aldehyde dehydrogenase family
XA13_RS09255	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
XA13_RS09270	COG0210	DNA helicase
XA13_RS09275	COG0598	Magnesium transport protein CorA
XA13_RS09285	COG0747	negative chemotaxis
XA13_RS09290	COG0601	transmembrane transport
XA13_RS09295	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XA13_RS09300	COG4172	Belongs to the ABC transporter superfamily
XA13_RS09305	COG1846	Transcriptional regulator
XA13_RS09355	COG4964	Belongs to the GSP D family
XA13_RS09395	COG2204	response regulator
XA13_RS09410	COG1595	DNA-templated transcription, initiation
XA13_RS09420	COG3474	cytochrome
XA13_RS09425	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
XA13_RS09440	COG3384	dioxygenase
XA13_RS09445	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
XA13_RS09470	COG2885	chlorophyll binding
XA13_RS09505	COG0697	spore germination
XA13_RS09510	COG0730	response to heat
XA13_RS09530	COG0583	DNA-binding transcription factor activity
XA13_RS09535	COG0427	acetyl-CoA hydrolase
XA13_RS09580	COG3468	outer membrane autotransporter barrel domain protein
XA13_RS09585	COG0424	maF-like protein
XA13_RS09590	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
XA13_RS09595	COG0799	negative regulation of ribosome biogenesis
XA13_RS09600	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
XA13_RS09605	COG0408	coproporphyrinogen oxidase activity
XA13_RS09610	COG0151	Belongs to the GarS family
XA13_RS09615	COG0217	transcriptional regulatory protein
XA13_RS09620	COG0433	COG0433 Predicted ATPase
XA13_RS09625	COG1115	amino acid carrier protein
XA13_RS09630	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
XA13_RS09640	COG1012	belongs to the aldehyde dehydrogenase family
XA13_RS09665	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
XA13_RS09680	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XA13_RS09690	COG0747	negative chemotaxis
XA13_RS09700	COG0473	3-isopropylmalate dehydrogenase activity
XA13_RS09705	COG2814	Major facilitator Superfamily
XA13_RS09710	COG1566	PFAM secretion protein HlyD family protein
XA13_RS09720	COG1846	Transcriptional regulator
XA13_RS09730	COG0697	spore germination
XA13_RS09740	COG0501	Belongs to the peptidase M48B family
XA13_RS09760	COG0583	DNA-binding transcription factor activity
XA13_RS09765	COG3842	ATPase activity
XA13_RS09770	COG1178	ABC-type Fe3 transport system permease component
XA13_RS09775	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XA13_RS09780	COG1840	ABC-type Fe3 transport system, periplasmic component
XA13_RS09785	COG0492	ferredoxin-NADP+ reductase activity
XA13_RS09805	COG2233	PERMEase
XA13_RS09810	COG0840	transmembrane signaling receptor activity
XA13_RS09815	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XA13_RS09845	COG4789	Type iii secretion
XA13_RS09910	COG4669	(LipO)protein
XA13_RS09945	COG4790	Type iii secretion
XA13_RS09950	COG4794	Type iii secretion
XA13_RS09955	COG4791	protein targeting
XA13_RS09960	COG4792	protein secretion
XA13_RS09975	COG1595	DNA-templated transcription, initiation
XA13_RS09995	COG2208	phosphoserine phosphatase activity
XA13_RS09995	COG2770	Histidine kinase
XA13_RS10005	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
XA13_RS10010	COG2172	sigma factor antagonist activity
XA13_RS10015	COG1366	Belongs to the anti-sigma-factor antagonist family
XA13_RS10020	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XA13_RS10050	COG2358	TRAP transporter, solute receptor (TAXI family
XA13_RS10055	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
XA13_RS10085	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XA13_RS10095	COG2252	PERMEase
XA13_RS10100	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
XA13_RS10110	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
XA13_RS10115	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
XA13_RS10145	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
XA13_RS10150	COG0789	Transcriptional regulator
XA13_RS10160	COG0678	peroxiredoxin activity
XA13_RS10160	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
XA13_RS10170	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
XA13_RS10175	COG0584	glycerophosphoryl diester phosphodiesterase
XA13_RS10180	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XA13_RS10190	COG4181	ATPase activity
XA13_RS10200	COG2823	Periplasmic or secreted lipoprotein
XA13_RS10210	COG3237	CsbD-like
XA13_RS10215	COG1181	Belongs to the D-alanine--D-alanine ligase family
XA13_RS10215	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
XA13_RS10220	COG0189	ligase activity
XA13_RS10220	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
XA13_RS10240	COG2833	Protein of unknown function (DUF455)
XA13_RS10245	COG2951	lytic endotransglycosylase activity
XA13_RS10265	COG1522	sequence-specific DNA binding
XA13_RS10275	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
XA13_RS10280	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
XA13_RS10285	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
XA13_RS10290	COG0196	riboflavin kinase activity
XA13_RS10295	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
XA13_RS10315	COG0210	DNA helicase
XA13_RS10320	COG4771	TonB-dependent receptor
XA13_RS10325	COG0488	(ABC) transporter
XA13_RS10330	COG2890	protein-(glutamine-N5) methyltransferase activity
XA13_RS10335	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XA13_RS10340	COG2171	N-acyltransferase activity
XA13_RS10375	COG1278	Cold shock
XA13_RS10395	COG0544	peptidyl-prolyl cis-trans isomerase activity
XA13_RS10400	COG0740	serine-type endopeptidase activity
XA13_RS10405	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
XA13_RS10410	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
XA13_RS10415	COG0583	DNA-binding transcription factor activity
XA13_RS10420	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XA13_RS10435	COG1024	Enoyl-CoA hydratase
XA13_RS10445	COG0183	Belongs to the thiolase family
XA13_RS10450	COG1028	Short-chain dehydrogenase reductase Sdr
XA13_RS10455	COG1960	acyl-CoA dehydrogenase activity
XA13_RS10470	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
XA13_RS10500	COG3468	outer membrane autotransporter barrel domain protein
XA13_RS10505	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XA13_RS10515	COG0556	nucleotide-excision repair
XA13_RS10520	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
XA13_RS10530	COG1104	cysteine desulfurase activity
XA13_RS10535	COG0822	iron-sulfur transferase activity
XA13_RS10540	COG0316	Belongs to the HesB IscA family
XA13_RS10545	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
XA13_RS10550	COG0443	Heat shock 70 kDa protein
XA13_RS10555	COG0633	Ferredoxin
XA13_RS10575	COG1024	Enoyl-CoA hydratase
XA13_RS10590	COG3395	kinase activity
XA13_RS10595	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
XA13_RS10610	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
XA13_RS10620	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XA13_RS10645	COG0747	negative chemotaxis
XA13_RS10650	COG0601	transmembrane transport
XA13_RS10655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XA13_RS10660	COG4172	Belongs to the ABC transporter superfamily
XA13_RS10665	COG0154	amidase activity
XA13_RS10710	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
XA13_RS10715	COG0425	Belongs to the sulfur carrier protein TusA family
XA13_RS10725	COG0228	four-way junction DNA binding
XA13_RS10730	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
XA13_RS10735	COG0336	Belongs to the RNA methyltransferase TrmD family
XA13_RS10740	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XA13_RS10760	COG0642	Histidine kinase
XA13_RS10775	COG0525	valine-tRNA ligase activity
XA13_RS10780	COG0105	UTP biosynthetic process
XA13_RS10785	COG0820	rRNA (adenine-C2-)-methyltransferase activity
XA13_RS10795	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
XA13_RS10800	COG0124	histidyl-tRNA synthetase
XA13_RS10805	COG2976	Protein conserved in bacteria
XA13_RS10810	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XA13_RS10815	COG1160	GTP binding
XA13_RS10820	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XA13_RS10825	COG1923	regulation of RNA biosynthetic process
XA13_RS10830	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
XA13_RS10835	COG0330	HflC and HflK could
XA13_RS10840	COG0330	HflC and HflK could
XA13_RS10845	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
XA13_RS10850	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
XA13_RS10855	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
XA13_RS10860	COG0828	Belongs to the bacterial ribosomal protein bS21 family
XA13_RS10870	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XA13_RS10905	COG0628	permease
XA13_RS10910	COG0842	Transport permease protein
XA13_RS10915	COG1131	(ABC) transporter
XA13_RS10985	COG0156	8-amino-7-oxononanoate synthase activity
XA13_RS10995	COG4106	trans-aconitate 2-methyltransferase activity
XA13_RS10995	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
XA13_RS11000	COG1380	Effector of murein hydrolase LrgA
XA13_RS11020	COG3284	Transcriptional regulator
XA13_RS11025	COG1012	belongs to the aldehyde dehydrogenase family
XA13_RS11040	COG2733	membrane
XA13_RS11045	COG0583	DNA-binding transcription factor activity
XA13_RS11050	COG0384	phenazine biosynthesis protein PhzF
XA13_RS11055	COG5507	3-demethylubiquinone-9 3-methyltransferase
XA13_RS11060	COG2169	Transcriptional regulator
XA13_RS11090	COG0659	secondary active sulfate transmembrane transporter activity
XA13_RS11115	COG1132	(ABC) transporter
XA13_RS11160	COG2207	Transcriptional regulator
XA13_RS11295	COG2346	COG2346, Truncated hemoglobins
XA13_RS11340	COG0183	Belongs to the thiolase family
XA13_RS11355	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XA13_RS11360	COG0633	Ferredoxin
XA13_RS11370	COG1024	Enoyl-CoA hydratase
XA13_RS11380	COG4638	Rieske (2fe-2S)
XA13_RS11390	COG0559	Belongs to the binding-protein-dependent transport system permease family
XA13_RS11410	COG2224	Isocitrate lyase
XA13_RS11415	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
XA13_RS11415	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
XA13_RS11430	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XA13_RS11435	COG0322	excinuclease ABC activity
XA13_RS11440	COG1472	Belongs to the glycosyl hydrolase 3 family
XA13_RS11445	COG0736	holo-[acyl-carrier-protein] synthase activity
XA13_RS11450	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
XA13_RS11460	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XA13_RS11465	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XA13_RS11490	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
XA13_RS11505	COG2032	superoxide dismutase activity
XA13_RS11520	COG1024	Enoyl-CoA hydratase
XA13_RS11530	COG1802	Transcriptional regulator
XA13_RS11540	COG0183	Belongs to the thiolase family
XA13_RS11545	COG1942	4-Oxalocrotonate Tautomerase
XA13_RS11555	COG4176	ABC-type proline glycine betaine transport system permease component
XA13_RS11570	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XA13_RS11575	COG2814	Major facilitator Superfamily
XA13_RS11580	COG0227	Belongs to the bacterial ribosomal protein bL28 family
XA13_RS11585	COG0267	Belongs to the bacterial ribosomal protein bL33 family
XA13_RS11615	COG2814	Major facilitator Superfamily
XA13_RS11620	COG0495	leucyl-tRNA aminoacylation
XA13_RS11635	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
XA13_RS11645	COG0154	amidase activity
XA13_RS11650	COG1250	3-hydroxyacyl-CoA dehydrogenase
XA13_RS11700	COG1530	ribonuclease E activity
XA13_RS11705	COG0077	Prephenate dehydratase
XA13_RS11720	COG1132	(ABC) transporter
XA13_RS11725	COG0859	PFAM glycosyl transferase family 9
XA13_RS11760	COG2194	sulfuric ester hydrolase activity
XA13_RS11765	COG0438	transferase activity, transferring glycosyl groups
XA13_RS11770	COG0463	Glycosyl transferase, family 2
XA13_RS11775	COG0726	polysaccharide deacetylase
XA13_RS11780	COG0438	transferase activity, transferring glycosyl groups
XA13_RS11795	COG1643	Atp-dependent helicase
XA13_RS11800	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
XA13_RS11800	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
XA13_RS11805	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
XA13_RS11815	COG0704	Plays a role in the regulation of phosphate uptake
XA13_RS11820	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
XA13_RS11825	COG1960	acyl-CoA dehydrogenase activity
XA13_RS11850	COG1177	transmembrane transport
XA13_RS11855	COG1176	ABC-type spermidine putrescine transport system, permease component I
XA13_RS11860	COG3842	ATPase activity
XA13_RS11865	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
XA13_RS11880	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
XA13_RS11885	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XA13_RS11895	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
XA13_RS11895	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
XA13_RS11915	COG0372	Belongs to the citrate synthase family
XA13_RS11920	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
XA13_RS11925	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
XA13_RS11930	COG1053	succinate dehydrogenase
XA13_RS11935	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
XA13_RS11940	COG2009	succinate dehydrogenase
XA13_RS11945	COG2188	Transcriptional regulator
XA13_RS11950	COG0039	L-malate dehydrogenase activity
XA13_RS11980	COG1981	membrane
XA13_RS12005	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
XA13_RS12015	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
XA13_RS12045	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
XA13_RS12050	COG0148	phosphopyruvate hydratase activity
XA13_RS12060	COG2877	3-deoxy-8-phosphooctulonate synthase activity
XA13_RS12065	COG0504	CTP synthase activity
XA13_RS12090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XA13_RS12100	COG0747	negative chemotaxis
XA13_RS12105	COG4172	Belongs to the ABC transporter superfamily
XA13_RS12110	COG1446	asparaginase
XA13_RS12140	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
XA13_RS12155	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
XA13_RS12160	COG0697	spore germination
XA13_RS12165	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
XA13_RS12175	COG3193	protein, possibly involved in utilization of glycolate and propanediol
XA13_RS12180	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
XA13_RS12185	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
XA13_RS12190	COG0791	NLP P60 protein
XA13_RS12205	COG0583	DNA-binding transcription factor activity
XA13_RS12220	COG0583	DNA-binding transcription factor activity
XA13_RS12230	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XA13_RS12245	COG0670	Belongs to the BI1 family
XA13_RS12250	COG3181	Tripartite tricarboxylate transporter family receptor
XA13_RS12260	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
XA13_RS12270	COG1381	Involved in DNA repair and RecF pathway recombination
XA13_RS12275	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
XA13_RS12280	COG0571	ribonuclease III activity
XA13_RS12285	COG0681	Belongs to the peptidase S26 family
XA13_RS12290	COG0481	GTPase activity
XA13_RS12295	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XA13_RS12320	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XA13_RS12325	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XA13_RS12340	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XA13_RS12345	COG0416	fatty acid biosynthetic process
XA13_RS12350	COG0333	Belongs to the bacterial ribosomal protein bL32 family
XA13_RS12355	COG1399	metal-binding, possibly nucleic acid-binding protein
XA13_RS12360	COG0424	maF-like protein
XA13_RS12370	COG3023	N-Acetylmuramoyl-L-alanine amidase
XA13_RS12375	COG1289	transmembrane transporter activity
XA13_RS12385	COG3022	response to hydroperoxide
XA13_RS12395	COG1028	Short-chain dehydrogenase reductase Sdr
XA13_RS12410	COG3486	L-lysine 6-monooxygenase (NADPH) activity
XA13_RS12440	COG2814	Major facilitator Superfamily
XA13_RS12460	COG3706	GGDEF domain
XA13_RS12485	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
XA13_RS12490	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
XA13_RS12495	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
XA13_RS12500	COG1674	ftsk spoiiie
XA13_RS12505	COG0492	ferredoxin-NADP+ reductase activity
XA13_RS12510	COG1193	negative regulation of DNA recombination
XA13_RS12530	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
XA13_RS12545	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
XA13_RS12550	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
XA13_RS12555	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
XA13_RS12565	COG0745	RESPONSE REGULATOR receiver
XA13_RS12610	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
XA13_RS12630	COG0612	Peptidase, M16
XA13_RS12640	COG0443	Heat shock 70 kDa protein
XA13_RS12650	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
XA13_RS12660	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
XA13_RS12665	COG1420	regulation of RNA biosynthetic process
XA13_RS12670	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
XA13_RS12675	COG0497	DNA recombination
XA13_RS12680	COG0735	belongs to the Fur family
XA13_RS12685	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XA13_RS12690	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
XA13_RS12695	COG0812	UDP-N-acetylmuramate dehydrogenase activity
XA13_RS12730	COG0446	pyridine nucleotide-disulphide oxidoreductase
XA13_RS12730	COG0404	The glycine cleavage system catalyzes the degradation of glycine
XA13_RS12735	COG4311	Sarcosine oxidase, delta subunit
XA13_RS12740	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XA13_RS12750	COG0583	DNA-binding transcription factor activity
XA13_RS12760	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
XA13_RS12790	COG4964	Belongs to the GSP D family
XA13_RS12850	COG0181	hydroxymethylbilane synthase activity
XA13_RS12855	COG0861	Integral membrane protein TerC family
XA13_RS12860	COG0861	Integral membrane protein TerC family
XA13_RS12865	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
XA13_RS12870	COG0045	succinate-CoA ligase (ADP-forming) activity
XA13_RS12880	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
XA13_RS12890	COG2137	regulation of response to DNA damage stimulus
XA13_RS12895	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
XA13_RS12915	COG1250	3-hydroxyacyl-CoA dehydrogenase
XA13_RS12915	COG1024	Enoyl-CoA hydratase
XA13_RS12920	COG3842	ATPase activity
XA13_RS12935	COG1028	Short-chain dehydrogenase reductase Sdr
XA13_RS12955	COG0583	DNA-binding transcription factor activity
XA13_RS12960	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XA13_RS12970	COG2974	May be involved in recombination
XA13_RS12975	COG0540	Belongs to the ATCase OTCase family
XA13_RS13050	COG0776	regulation of translation
XA13_RS13055	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XA13_RS13055	COG0072	phenylalanine-tRNA ligase activity
XA13_RS13060	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
XA13_RS13065	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
XA13_RS13070	COG0291	Belongs to the bacterial ribosomal protein bL35 family
XA13_RS13085	COG0756	dUTP diphosphatase activity
XA13_RS13095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XA13_RS13110	COG0500	methyltransferase
XA13_RS13125	COG0586	Pfam SNARE associated Golgi protein
XA13_RS13155	COG1609	Transcriptional regulator
XA13_RS13160	COG4172	Belongs to the ABC transporter superfamily
XA13_RS13165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XA13_RS13170	COG0601	transmembrane transport
XA13_RS13175	COG0747	negative chemotaxis
XA13_RS13190	COG1280	lysine exporter protein (LysE YggA)
XA13_RS13205	COG2814	Major facilitator Superfamily
XA13_RS13235	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
XA13_RS13255	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
XA13_RS13295	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XA13_RS13300	COG1116	anion transmembrane transporter activity
XA13_RS13310	COG1228	amidohydrolase
XA13_RS13325	COG0477	Major facilitator Superfamily
XA13_RS13335	COG3550	peptidyl-serine autophosphorylation
XA13_RS13350	COG0519	Catalyzes the synthesis of GMP from XMP
XA13_RS13350	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XA13_RS13395	COG0420	3'-5' exonuclease activity
XA13_RS13400	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XA13_RS13430	COG0395	ABC-type sugar transport system, permease component
XA13_RS13440	COG3842	ATPase activity
XA13_RS13470	COG3181	Tripartite tricarboxylate transporter family receptor
XA13_RS13505	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XA13_RS13530	COG0602	queuosine metabolic process
XA13_RS13535	COG0720	synthase
XA13_RS13540	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
XA13_RS13545	COG0235	Class ii aldolase
XA13_RS13570	COG3210	domain, Protein
XA13_RS13570	COG3064	Membrane
XA13_RS13570	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
XA13_RS13575	COG0047	phosphoribosylformylglycinamidine synthase activity
XA13_RS13575	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
XA13_RS13580	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
XA13_RS13585	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
XA13_RS13585	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
XA13_RS13590	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XA13_RS13610	COG3539	Fimbrial protein
XA13_RS13620	COG2050	protein possibly involved in aromatic compounds catabolism
XA13_RS13625	COG1024	Enoyl-CoA hydratase
XA13_RS13630	COG1012	belongs to the aldehyde dehydrogenase family
XA13_RS13640	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
XA13_RS13645	COG2151	metal-sulfur cluster biosynthetic enzyme
XA13_RS13650	COG3396	Phenylacetate-CoA oxygenase
XA13_RS13655	COG3460	Phenylacetate-CoA oxygenase
XA13_RS13660	COG3396	Phenylacetate-CoA oxygenase
XA13_RS13665	COG3327	negative regulation of DNA-templated transcription, initiation
XA13_RS13675	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
XA13_RS13680	COG0501	Belongs to the peptidase M48B family
XA13_RS13685	COG1162	GTPase activity
XA13_RS13690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XA13_RS13695	COG0601	transmembrane transport
XA13_RS13700	COG0747	negative chemotaxis
XA13_RS13745	COG0668	transmembrane transport
XA13_RS13750	COG0165	Argininosuccinate lyase
XA13_RS13770	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
XA13_RS13775	COG0303	'Molybdopterin
XA13_RS13780	COG0521	Mo-molybdopterin cofactor biosynthetic process
XA13_RS13795	COG0315	cyclic pyranopterin monophosphate synthase activity
XA13_RS13805	COG0412	Dienelactone hydrolase
XA13_RS13815	COG0678	peroxiredoxin activity
XA13_RS13825	COG0697	spore germination
XA13_RS13830	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
XA13_RS13855	COG0789	Transcriptional regulator
XA13_RS13875	COG1028	Short-chain dehydrogenase reductase Sdr
XA13_RS13885	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
XA13_RS13890	COG1845	cytochrome c oxidase, subunit III
XA13_RS13895	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XA13_RS13905	COG0477	Major facilitator Superfamily
XA13_RS13935	COG3468	outer membrane autotransporter barrel domain protein
XA13_RS13945	COG1309	transcriptional regulator
XA13_RS13950	COG2271	Major facilitator Superfamily
XA13_RS13985	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
XA13_RS13985	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
XA13_RS13985	COG0506	proline dehydrogenase activity
XA13_RS13995	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XA13_RS13995	COG3008	intermembrane lipid transfer
XA13_RS14000	COG2995	paraquat-inducible protein a
XA13_RS14005	COG0542	response to heat
XA13_RS14010	COG4953	penicillin-binding protein 1C
XA13_RS14020	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
XA13_RS14025	COG1278	Cold shock
XA13_RS14035	COG0183	Belongs to the thiolase family
XA13_RS14040	COG0038	chloride channel
XA13_RS14045	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XA13_RS14050	COG1570	exodeoxyribonuclease VII activity
XA13_RS14060	COG0811	peptide transport
XA13_RS14065	COG0848	biopolymer transport protein
XA13_RS14070	COG1663	tetraacyldisaccharide 4'-kinase activity
XA13_RS14075	COG2835	tetraacyldisaccharide 4'-kinase activity
XA13_RS14080	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
XA13_RS14085	COG0563	adenylate kinase activity
XA13_RS14095	COG0728	peptidoglycan biosynthetic process
XA13_RS14105	COG0268	Binds directly to 16S ribosomal RNA
XA13_RS14135	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
XA13_RS14160	COG0436	Aminotransferase
XA13_RS14165	COG3737	Protein of unknown function (DUF498/DUF598)
XA13_RS14170	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
XA13_RS14175	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
XA13_RS14180	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
XA13_RS14190	COG0305	Participates in initiation and elongation during chromosome replication
XA13_RS14200	COG0359	binds to the 23S rRNA
XA13_RS14205	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
XA13_RS14210	COG2965	DNA replication, synthesis of RNA primer
XA13_RS14215	COG0360	Binds together with S18 to 16S ribosomal RNA
XA13_RS14220	COG1469	GTP cyclohydrolase I activity
XA13_RS14225	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
XA13_RS14230	COG0142	geranyltranstransferase activity
XA13_RS14235	COG1722	exodeoxyribonuclease VII activity
XA13_RS14245	COG3181	Tripartite tricarboxylate transporter family receptor
XA13_RS14265	COG2239	Acts as a magnesium transporter
XA13_RS14275	COG2855	membrane
XA13_RS14285	COG1473	amidohydrolase
XA13_RS14290	COG0318	PFAM AMP-dependent synthetase and ligase
XA13_RS14315	COG1501	Belongs to the glycosyl hydrolase 31 family
XA13_RS14320	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
XA13_RS14325	COG2011	ABC-type metal ion transport system permease component
XA13_RS14345	COG1454	alcohol dehydrogenase
XA13_RS14375	COG2186	Transcriptional regulator
XA13_RS14380	COG3181	Tripartite tricarboxylate transporter family receptor
XA13_RS14400	COG1175	transmembrane transport
XA13_RS14405	COG0395	ABC-type sugar transport system, permease component
XA13_RS14410	COG3842	ATPase activity
XA13_RS14415	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XA13_RS14425	COG1653	transport
XA13_RS14445	COG2818	Glycosylase
XA13_RS14450	COG2982	Protein involved in outer membrane biogenesis
XA13_RS14460	COG1309	transcriptional regulator
XA13_RS14465	COG1028	Short-chain dehydrogenase reductase Sdr
XA13_RS14525	COG0583	DNA-binding transcription factor activity
XA13_RS14530	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
XA13_RS14535	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
XA13_RS14550	COG1028	Short-chain dehydrogenase reductase Sdr
XA13_RS14555	COG0477	Major facilitator Superfamily
XA13_RS14565	COG0583	DNA-binding transcription factor activity
XA13_RS14570	COG1448	Aminotransferase
XA13_RS14575	COG1418	mRNA catabolic process
XA13_RS14600	COG1063	alcohol dehydrogenase
XA13_RS14620	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XA13_RS14630	COG0318	PFAM AMP-dependent synthetase and ligase
XA13_RS14640	COG1522	sequence-specific DNA binding
XA13_RS14645	COG3181	Tripartite tricarboxylate transporter family receptor
XA13_RS14650	COG0307	riboflavin synthase, alpha
XA13_RS14655	COG0154	amidase activity
XA13_RS14675	COG2807	transmembrane transport
XA13_RS14680	COG0590	tRNA wobble adenosine to inosine editing
XA13_RS14690	COG0583	DNA-binding transcription factor activity
XA13_RS14705	COG1902	pentaerythritol trinitrate reductase activity
XA13_RS14725	COG0559	Belongs to the binding-protein-dependent transport system permease family
XA13_RS14730	COG0251	oxidation-reduction process
XA13_RS14735	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
XA13_RS14745	COG1414	Transcriptional regulator
XA13_RS14750	COG1028	Short-chain dehydrogenase reductase Sdr
XA13_RS14765	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XA13_RS14780	COG1024	Enoyl-CoA hydratase
XA13_RS14785	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XA13_RS14790	COG0154	amidase activity
XA13_RS14830	COG3909	cytochrome
XA13_RS14835	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
XA13_RS14840	COG0625	glutathione transferase activity
XA13_RS14845	COG0730	response to heat
XA13_RS14850	COG0482	sulfurtransferase activity
XA13_RS14855	COG0583	DNA-binding transcription factor activity
XA13_RS14875	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
XA13_RS14900	COG2819	hydrolase of the alpha beta superfamily
XA13_RS14905	COG0247	lactate metabolic process
XA13_RS14910	COG0277	FAD linked oxidase domain protein
XA13_RS14915	COG0277	FAD linked oxidase domain protein
XA13_RS14920	COG0277	FAD linked oxidase domain protein
XA13_RS14925	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
XA13_RS14925	COG3064	Membrane
XA13_RS14925	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
XA13_RS14925	COG3210	domain, Protein
XA13_RS14925	COG3210	domain, Protein
XA13_RS14925	COG3064	Membrane
XA13_RS14930	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
XA13_RS14935	COG0312	modulator of DNA gyrase
XA13_RS14970	COG1666	GTP binding
XA13_RS15015	COG3220	belongs to the UPF0276 family
XA13_RS15035	COG0640	Transcriptional regulator
XA13_RS15040	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
XA13_RS15045	COG1845	cytochrome c oxidase, subunit III
XA13_RS15050	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XA13_RS15060	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
XA13_RS15095	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XA13_RS15100	COG0583	DNA-binding transcription factor activity
XA13_RS15130	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XA13_RS15130	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XA13_RS15145	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
XA13_RS15150	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
XA13_RS15160	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
XA13_RS15175	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
XA13_RS15180	COG0316	Belongs to the HesB IscA family
XA13_RS15190	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
XA13_RS15195	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
XA13_RS15200	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
XA13_RS15205	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
XA13_RS15210	COG0312	modulator of DNA gyrase
XA13_RS15215	COG3028	Belongs to the UPF0307 family
XA13_RS15230	COG1116	anion transmembrane transporter activity
XA13_RS15235	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XA13_RS15240	COG1335	isochorismatase
XA13_RS15245	COG0346	lactoylglutathione lyase activity
XA13_RS15250	COG0513	Belongs to the DEAD box helicase family
XA13_RS15255	COG3069	C4-dicarboxylate transmembrane transporter activity
XA13_RS15260	COG1802	Transcriptional regulator
XA13_RS15275	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XA13_RS15275	COG0045	succinate-CoA ligase (ADP-forming) activity
XA13_RS15275	COG1042	CoA-binding domain protein
XA13_RS15280	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XA13_RS15295	COG1522	sequence-specific DNA binding
XA13_RS15330	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XA13_RS15335	COG1696	Membrane protein involved in D-alanine export
XA13_RS15360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XA13_RS15370	COG2264	protein methyltransferase activity
XA13_RS15375	COG0439	Biotin carboxylase
XA13_RS15380	COG0511	ligase activity, forming carbon-carbon bonds
XA13_RS15385	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
XA13_RS15390	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XA13_RS15395	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XA13_RS15400	COG3150	esterase
XA13_RS15405	COG0557	exoribonuclease II activity
XA13_RS15415	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
XA13_RS15435	COG1522	sequence-specific DNA binding
XA13_RS15440	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XA13_RS15445	COG1028	Short-chain dehydrogenase reductase Sdr
XA13_RS15465	COG0653	protein targeting
XA13_RS15470	COG0739	heme binding
XA13_RS15480	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
XA13_RS15485	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
XA13_RS15495	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
XA13_RS15500	COG1181	Belongs to the D-alanine--D-alanine ligase family
XA13_RS15505	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XA13_RS15510	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
XA13_RS15520	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
XA13_RS15525	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XA13_RS15530	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
XA13_RS15540	COG3116	cell division
XA13_RS15545	COG0275	rRNA processing
XA13_RS15550	COG2001	Belongs to the MraZ family
XA13_RS15560	COG0488	(ABC) transporter
XA13_RS15565	COG0418	dihydroorotase activity
XA13_RS15570	COG1473	amidohydrolase
XA13_RS15620	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
XA13_RS15625	COG4654	Cytochrome c, class I
XA13_RS15630	COG0129	dihydroxy-acid dehydratase activity
XA13_RS15635	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
XA13_RS15690	COG2084	Dehydrogenase
XA13_RS15695	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
XA13_RS15710	COG2096	Adenosyltransferase
XA13_RS15720	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
XA13_RS15725	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
XA13_RS15735	COG0523	cobalamin synthesis protein
XA13_RS15740	COG0735	belongs to the Fur family
XA13_RS15760	COG0803	Belongs to the bacterial solute-binding protein 9 family
XA13_RS15770	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
XA13_RS15780	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XA13_RS15790	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
XA13_RS15795	COG1560	Kdo2-lipid A biosynthetic process
XA13_RS15805	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
XA13_RS15820	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
XA13_RS15825	COG1950	PFAM Membrane protein of
XA13_RS15840	COG0583	DNA-binding transcription factor activity
XA13_RS15850	COG0477	Major facilitator Superfamily
XA13_RS15865	COG0617	tRNA 3'-terminal CCA addition
XA13_RS15875	COG0513	Belongs to the DEAD box helicase family
XA13_RS15880	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
XA13_RS15895	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XA13_RS15900	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
XA13_RS15960	COG1280	lysine exporter protein (LysE YggA)
XA13_RS15975	COG0405	Gamma-glutamyltransferase
XA13_RS15985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XA13_RS16015	COG1309	transcriptional regulator
XA13_RS16025	COG3181	Tripartite tricarboxylate transporter family receptor
XA13_RS16035	COG0745	RESPONSE REGULATOR receiver
XA13_RS16100	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
XA13_RS16125	COG0582	viral genome integration into host DNA
XA13_RS16130	COG0012	GTP binding
XA13_RS16140	COG0193	aminoacyl-tRNA hydrolase activity
XA13_RS16145	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
XA13_RS16150	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
XA13_RS16160	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
XA13_RS16165	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
XA13_RS16175	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
XA13_RS16200	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
XA13_RS16210	COG1368	sulfuric ester hydrolase activity
XA13_RS16215	COG0642	Histidine kinase
XA13_RS16220	COG0745	RESPONSE REGULATOR receiver
XA13_RS16225	COG0277	FAD linked oxidase domain protein
XA13_RS16240	COG0166	Belongs to the GPI family
XA13_RS16245	COG0438	transferase activity, transferring glycosyl groups
XA13_RS16250	COG0438	transferase activity, transferring glycosyl groups
XA13_RS16265	COG0438	transferase activity, transferring glycosyl groups
XA13_RS16280	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
XA13_RS16285	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XA13_RS16290	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
XA13_RS16300	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
XA13_RS16310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XA13_RS16315	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
XA13_RS16325	COG0747	negative chemotaxis
XA13_RS16330	COG0601	transmembrane transport
XA13_RS16335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XA13_RS16355	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
XA13_RS16360	COG0830	nickel cation binding
XA13_RS16370	COG0804	urea catabolic process
XA13_RS16375	COG0832	Belongs to the urease beta subunit family
XA13_RS16385	COG0831	urea catabolic process
XA13_RS16390	COG0829	nickel cation binding
XA13_RS16400	COG0633	Ferredoxin
XA13_RS16415	COG2188	Transcriptional regulator
XA13_RS16440	COG2719	SpoVR family
XA13_RS16445	COG2718	Belongs to the UPF0229 family
XA13_RS16460	COG1028	Short-chain dehydrogenase reductase Sdr
XA13_RS16465	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XA13_RS16480	COG1960	acyl-CoA dehydrogenase activity
XA13_RS16525	COG0183	Belongs to the thiolase family
XA13_RS16530	COG2030	dehydratase
XA13_RS16585	COG0328	RNA-DNA hybrid ribonuclease activity
XA13_RS16590	COG2226	methyltransferase
XA13_RS16595	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XA13_RS16600	COG0741	lytic transglycosylase activity
XA13_RS16600	COG1388	LysM domain
XA13_RS16620	COG2979	Protein of unknown function (DUF533)
XA13_RS16655	COG1271	oxidase subunit
XA13_RS16660	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XA13_RS16665	COG0850	regulation of cytokinetic process
XA13_RS16670	COG2894	cell division
XA13_RS16675	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
XA13_RS16695	COG0488	(ABC) transporter
XA13_RS16710	COG0601	transmembrane transport
XA13_RS16720	COG1215	transferase activity, transferring glycosyl groups
XA13_RS16735	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
XA13_RS16745	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XA13_RS16765	COG0318	PFAM AMP-dependent synthetase and ligase
XA13_RS16770	COG2188	Transcriptional regulator
XA13_RS16775	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
XA13_RS16780	COG2814	Major facilitator Superfamily
XA13_RS16790	COG0259	pyridoxamine-phosphate oxidase activity
XA13_RS16795	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
XA13_RS16810	COG0583	DNA-binding transcription factor activity
XA13_RS16815	COG1960	acyl-CoA dehydrogenase activity
XA13_RS16835	COG0134	indole-3-glycerol-phosphate synthase activity
XA13_RS16840	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
XA13_RS16845	COG0512	Glutamine amidotransferase of anthranilate synthase
XA13_RS16855	COG0546	phosphoglycolate phosphatase activity
XA13_RS16860	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
XA13_RS16865	COG2967	ApaG domain
XA13_RS16870	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
XA13_RS16875	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XA13_RS16880	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XA13_RS16885	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XA13_RS16895	COG0037	tRNA processing
XA13_RS16905	COG3634	alkyl hydroperoxide reductase activity
XA13_RS16910	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XA13_RS16915	COG1024	Enoyl-CoA hydratase
XA13_RS16940	COG0356	it plays a direct role in the translocation of protons across the membrane
XA13_RS16950	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
XA13_RS16955	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
XA13_RS16960	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
XA13_RS16965	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
XA13_RS16970	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
XA13_RS16975	COG0355	proton-transporting ATP synthase activity, rotational mechanism
XA13_RS16985	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
XA13_RS16990	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
XA13_RS16995	COG0210	DNA helicase
XA13_RS17005	COG2195	Cleaves the N-terminal amino acid of tripeptides
XA13_RS17015	COG4172	Belongs to the ABC transporter superfamily
XA13_RS17020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XA13_RS17025	COG0601	transmembrane transport
XA13_RS17045	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XA13_RS17050	COG1024	Enoyl-CoA hydratase
XA13_RS17055	COG1024	Enoyl-CoA hydratase
XA13_RS17080	COG1250	3-hydroxyacyl-CoA dehydrogenase
XA13_RS17110	COG2132	Multicopper oxidase
XA13_RS17120	COG1250	3-hydroxyacyl-CoA dehydrogenase
XA13_RS17120	COG1024	Enoyl-CoA hydratase
XA13_RS17130	COG1414	Transcriptional regulator
XA13_RS17140	COG0154	amidase activity
XA13_RS17170	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XA13_RS17175	COG3568	Endonuclease Exonuclease Phosphatase
XA13_RS17180	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
XA13_RS17215	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
XA13_RS17225	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
XA13_RS17240	COG1137	ATPase activity
XA13_RS17245	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
XA13_RS17255	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
XA13_RS17260	COG2010	Cytochrome c
XA13_RS17260	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XA13_RS17270	COG1660	Displays ATPase and GTPase activities
XA13_RS17275	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
XA13_RS17310	COG3181	Tripartite tricarboxylate transporter family receptor
XA13_RS17320	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XA13_RS17325	COG2890	protein-(glutamine-N5) methyltransferase activity
XA13_RS17330	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
XA13_RS17335	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
XA13_RS17385	COG1960	acyl-CoA dehydrogenase activity
XA13_RS17395	COG0183	Belongs to the thiolase family
XA13_RS17400	COG1522	sequence-specific DNA binding
XA13_RS17405	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XA13_RS17425	COG1024	Enoyl-CoA hydratase
XA13_RS17440	COG0604	alcohol dehydrogenase
XA13_RS17460	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XA13_RS17470	COG1960	acyl-CoA dehydrogenase activity
XA13_RS17475	COG1960	acyl-CoA dehydrogenase activity
XA13_RS17480	COG0277	FAD linked oxidase domain protein
XA13_RS17490	COG3181	Tripartite tricarboxylate transporter family receptor
XA13_RS17515	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XA13_RS17525	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XA13_RS17530	COG3181	Tripartite tricarboxylate transporter family receptor
XA13_RS17535	COG1960	acyl-CoA dehydrogenase activity
XA13_RS17555	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XA13_RS17560	COG1024	Enoyl-CoA hydratase
XA13_RS17565	COG1960	acyl-CoA dehydrogenase activity
XA13_RS17585	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
XA13_RS17590	COG0022	dehydrogenase e1 component
XA13_RS17595	COG1024	Enoyl-CoA hydratase
XA13_RS17600	COG0508	dehydrogenase complex catalyzes the overall conversion of
XA13_RS17620	COG0683	leucine binding
XA13_RS17625	COG0559	Belongs to the binding-protein-dependent transport system permease family
XA13_RS17630	COG0411	ABC transporter
XA13_RS17640	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XA13_RS17655	COG3181	Tripartite tricarboxylate transporter family receptor
XA13_RS17685	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
XA13_RS17690	COG0793	Belongs to the peptidase S41A family
XA13_RS17695	COG4942	peptidase
XA13_RS17700	COG0588	phosphoglycerate mutase activity
XA13_RS17705	COG1054	Belongs to the UPF0176 family
XA13_RS17710	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
XA13_RS17715	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
XA13_RS17720	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
XA13_RS17725	COG3181	Tripartite tricarboxylate transporter family receptor
XA13_RS17740	COG2226	methyltransferase
XA13_RS17745	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
XA13_RS17760	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XA13_RS17765	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
XA13_RS17790	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
XA13_RS17815	COG1335	isochorismatase
XA13_RS17820	COG2309	aminopeptidase activity
XA13_RS17825	COG0596	Alpha beta hydrolase
XA13_RS17830	COG3473	Maleate cis-trans isomerase
XA13_RS17840	COG2068	MobA-Related Protein
XA13_RS17865	COG2204	response regulator
XA13_RS17870	COG5000	phosphorelay sensor kinase activity
XA13_RS17880	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
XA13_RS17880	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XA13_RS17890	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
XA13_RS17920	COG0583	DNA-binding transcription factor activity
XA13_RS17935	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
XA13_RS17940	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XA13_RS17945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XA13_RS17960	COG0758	DNA mediated transformation
XA13_RS17965	COG1522	sequence-specific DNA binding
XA13_RS17975	COG0242	peptide deformylase activity
XA13_RS17990	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
XA13_RS18000	COG0546	phosphoglycolate phosphatase activity
XA13_RS18020	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XA13_RS18025	COG1942	4-Oxalocrotonate Tautomerase
XA13_RS18030	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XA13_RS18055	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
XA13_RS18075	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XA13_RS18080	COG1024	Enoyl-CoA hydratase
XA13_RS18085	COG1414	Transcriptional regulator
XA13_RS18090	COG0318	PFAM AMP-dependent synthetase and ligase
XA13_RS18095	COG3181	Tripartite tricarboxylate transporter family receptor
XA13_RS18125	COG0583	DNA-binding transcription factor activity
XA13_RS18140	COG3422	double-strand break repair
XA13_RS18145	COG0330	HflC and HflK could
XA13_RS18155	COG0251	oxidation-reduction process
XA13_RS18200	COG3723	Recombinational DNA repair protein, rece pathway
XA13_RS18235	COG0582	viral genome integration into host DNA
XA13_RS18260	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
XA13_RS18270	COG0706	membrane insertase activity
XA13_RS18275	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
XA13_RS18280	COG0594	ribonuclease P activity
XA13_RS18285	COG0230	Belongs to the bacterial ribosomal protein bL34 family
XA13_RS18290	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
XA13_RS18305	COG1414	Transcriptional regulator
XA13_RS18310	COG0154	amidase activity
XA13_RS18325	COG1304	FMN binding
XA13_RS18345	COG1960	acyl-CoA dehydrogenase activity
XA13_RS18365	COG1960	acyl-CoA dehydrogenase activity
XA13_RS18380	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XA13_RS18395	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
XA13_RS18400	COG3181	Tripartite tricarboxylate transporter family receptor
XA13_RS18410	COG2358	TRAP transporter, solute receptor (TAXI family
XA13_RS18420	COG1629	transport
XA13_RS18425	COG2922	Belongs to the Smg family
XA13_RS18450	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
XA13_RS18455	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XA13_RS18460	COG1028	Short-chain dehydrogenase reductase Sdr
XA13_RS18465	COG1012	belongs to the aldehyde dehydrogenase family
XA13_RS18475	COG0028	Belongs to the TPP enzyme family
XA13_RS18480	COG1522	sequence-specific DNA binding
XA13_RS18485	COG3781	membrane
XA13_RS18495	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
XA13_RS18515	COG4206	TonB-dependent receptor
XA13_RS18520	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
XA13_RS18525	COG2022	thiamine diphosphate biosynthetic process
XA13_RS18530	COG0351	phosphomethylpyrimidine kinase
XA13_RS18535	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XA13_RS18550	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
XA13_RS18560	COG0628	permease
XA13_RS18570	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XA13_RS18580	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
XA13_RS18585	COG0049	tRNA binding
XA13_RS18590	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
XA13_RS18595	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
XA13_RS18600	COG0051	transcription antitermination factor activity, RNA binding
XA13_RS18605	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
XA13_RS18610	COG0088	Forms part of the polypeptide exit tunnel
XA13_RS18615	COG0089	rRNA binding
XA13_RS18620	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
XA13_RS18625	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
XA13_RS18630	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
XA13_RS18635	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
XA13_RS18640	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
XA13_RS18645	COG0255	Belongs to the universal ribosomal protein uL29 family
XA13_RS18650	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
XA13_RS18670	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
XA13_RS18675	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
XA13_RS18680	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
XA13_RS18685	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
XA13_RS18690	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
XA13_RS18695	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
XA13_RS18700	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
XA13_RS18705	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
XA13_RS18710	COG1841	ribosomal large subunit assembly
XA13_RS18715	COG0200	Binds to the 23S rRNA
XA13_RS18720	COG0201	protein transport
XA13_RS18725	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
XA13_RS18730	COG0257	Belongs to the bacterial ribosomal protein bL36 family
XA13_RS18735	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
XA13_RS18740	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
XA13_RS18745	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
XA13_RS18750	COG0202	RNA polymerase activity
XA13_RS18755	COG0203	ribosomal protein L17
XA13_RS18760	COG0537	adenosine 5'-monophosphoramidase activity
XA13_RS18765	COG1324	tolerance protein
XA13_RS18770	COG4232	protein-disulfide reductase activity
XA13_RS18785	COG0218	Necessary for normal cell division and for the maintenance of normal septation
XA13_RS18795	COG1333	cytochrome c biogenesis protein
XA13_RS18800	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XA13_RS18815	COG1965	Belongs to the frataxin family
XA13_RS18825	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
XA13_RS18830	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
XA13_RS18835	COG0232	Belongs to the dGTPase family. Type 2 subfamily
XA13_RS18850	COG2814	Major facilitator Superfamily
XA13_RS18855	COG0629	single-stranded DNA binding
XA13_RS18895	COG0402	S-adenosylhomocysteine deaminase activity
XA13_RS18905	COG0438	transferase activity, transferring glycosyl groups
XA13_RS18925	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XA13_RS18950	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
XA13_RS18955	COG2186	Transcriptional regulator
XA13_RS18975	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XA13_RS18980	COG1956	GAF domain-containing protein
XA13_RS18985	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XA13_RS19000	COG1652	LysM domain
XA13_RS19015	COG0220	tRNA (guanine-N7-)-methyltransferase activity
XA13_RS19030	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
XA13_RS19060	COG3181	Tripartite tricarboxylate transporter family receptor
XA13_RS19075	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XA13_RS19090	COG1024	Enoyl-CoA hydratase
XA13_RS19105	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XA13_RS19110	COG1309	transcriptional regulator
XA13_RS19115	COG2816	NAD+ diphosphatase activity
XA13_RS19120	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
XA13_RS19205	COG2814	Major facilitator Superfamily
XA13_RS19210	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
XA13_RS19230	COG1999	signal sequence binding
XA13_RS19235	COG0109	protoheme IX farnesyltransferase activity
XA13_RS19275	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XA13_RS19295	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
XA13_RS19300	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XA13_RS19310	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
XA13_RS19315	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
XA13_RS19325	COG0070	glutamate synthase
XA13_RS19325	COG0069	glutamate synthase activity
XA13_RS19325	COG0067	glutamate synthase
XA13_RS19335	COG3047	cAMP biosynthetic process
XA13_RS19345	COG1127	ABC transporter
XA13_RS19350	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XA13_RS19355	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XA13_RS19360	COG2853	Lipoprotein
XA13_RS19370	COG1131	(ABC) transporter
XA13_RS19375	COG0842	Transport permease protein
XA13_RS19385	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
XA13_RS19390	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
XA13_RS19395	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
XA13_RS19400	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XA13_RS19405	COG0131	Imidazoleglycerol-phosphate dehydratase
XA13_RS19410	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
XA13_RS19415	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
XA13_RS19420	COG0107	imidazoleglycerol-phosphate synthase activity
XA13_RS19425	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
XA13_RS19430	COG0140	phosphoribosyl-ATP diphosphatase activity
XA13_RS19435	COG0537	adenosine 5'-monophosphoramidase activity
XA13_RS19440	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XA13_RS19445	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XA13_RS19460	COG3181	Tripartite tricarboxylate transporter family receptor
XA13_RS19495	COG3702	type iv secretory pathway
XA13_RS19500	COG3451	type IV secretory pathway VirB4
XA13_RS19515	COG3736	Type IV secretory pathway, component VirB8
XA13_RS19520	COG3504	Conjugal transfer protein
XA13_RS19525	COG2948	multi-organism process
XA13_RS19530	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
XA13_RS19540	COG0697	spore germination
XA13_RS19560	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
XA13_RS19565	COG0747	negative chemotaxis
XA13_RS19570	COG0601	transmembrane transport
XA13_RS19575	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XA13_RS19580	COG0444	Belongs to the ABC transporter superfamily
XA13_RS19590	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
XA13_RS19600	COG0494	nUDIX hydrolase
XA13_RS19640	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
XA13_RS19645	COG0237	dephospho-CoA kinase activity
XA13_RS19650	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
XA13_RS19665	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
XA13_RS19670	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
XA13_RS19680	COG0477	Major facilitator Superfamily
XA13_RS19685	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
XA13_RS19700	COG1126	abc transporter atp-binding protein
XA13_RS19705	COG0765	amino acid transport
XA13_RS19710	COG4597	amino acid ABC transporter
XA13_RS19715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XA13_RS19720	COG2884	Cell division ATP-binding protein ftsE
XA13_RS19725	COG2177	Part of the ABC transporter FtsEX involved in
XA13_RS19730	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
XA13_RS19740	COG1194	a g-specific adenine glycosylase
XA13_RS19750	COG2226	methyltransferase
XA13_RS19760	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XA13_RS19765	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XA13_RS19780	COG1024	Enoyl-CoA hydratase
XA13_RS19800	COG1024	Enoyl-CoA hydratase
XA13_RS19805	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XA13_RS19810	COG3181	Tripartite tricarboxylate transporter family receptor
XA13_RS19820	COG0753	catalase activity
XA13_RS19825	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XA13_RS19830	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
XA13_RS19840	COG2175	clavaminate synthase activity
XA13_RS19845	COG1473	amidohydrolase
XA13_RS19850	COG4608	Belongs to the ABC transporter superfamily
XA13_RS19855	COG0444	Belongs to the ABC transporter superfamily
XA13_RS19870	COG0747	negative chemotaxis
XA13_RS19875	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
XA13_RS19910	COG0436	Aminotransferase
XA13_RS19915	COG1278	Cold shock