locus-tag	class	description
AC879_RS00005	COG0445	tRNA wobble uridine modification
AC879_RS00010	COG0357	Ribosomal RNA small subunit methyltransferase G
AC879_RS00015	COG1192	Involved in chromosome partitioning
AC879_RS00025	COG1475	DNA binding
AC879_RS00030	COG0252	asparaginase activity
AC879_RS00055	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AC879_RS00065	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AC879_RS00075	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AC879_RS00080	COG0081	regulation of translation
AC879_RS00085	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AC879_RS00090	COG0222	ribosome binding
AC879_RS00095	COG0085	RNA polymerase activity
AC879_RS00100	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AC879_RS00140	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AC879_RS00165	COG1024	Enoyl-CoA hydratase
AC879_RS00185	COG0752	glycyl-tRNA synthetase alpha subunit
AC879_RS00190	COG0751	glycine-tRNA ligase activity
AC879_RS00195	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AC879_RS00200	COG0204	Acyl-transferase
AC879_RS00215	COG0242	peptide deformylase activity
AC879_RS00250	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AC879_RS00255	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AC879_RS00260	COG2813	Specifically methylates the guanine in position
AC879_RS00260	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AC879_RS00275	COG2223	nitrite transmembrane transporter activity
AC879_RS00285	COG1794	racemase activity, acting on amino acids and derivatives
AC879_RS00290	COG1126	abc transporter atp-binding protein
AC879_RS00295	COG0765	amino acid transport
AC879_RS00300	COG0765	amino acid transport
AC879_RS00305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AC879_RS00370	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AC879_RS00400	COG0326	Molecular chaperone. Has ATPase activity
AC879_RS00405	COG0625	glutathione transferase activity
AC879_RS00420	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AC879_RS00425	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AC879_RS00455	COG0438	transferase activity, transferring glycosyl groups
AC879_RS00460	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AC879_RS00465	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AC879_RS00495	COG0859	PFAM glycosyl transferase family 9
AC879_RS00510	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AC879_RS00520	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AC879_RS00525	COG1127	ABC transporter
AC879_RS00545	COG1686	Belongs to the peptidase S11 family
AC879_RS00555	COG2921	Belongs to the UPF0250 family
AC879_RS00560	COG0321	lipoyl(octanoyl) transferase activity
AC879_RS00565	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AC879_RS00600	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AC879_RS00610	COG0018	arginyl-trna synthetase
AC879_RS00630	COG0395	ABC-type sugar transport system, permease component
AC879_RS00635	COG1175	transmembrane transport
AC879_RS00640	COG1653	transport
AC879_RS00645	COG3842	ATPase activity
AC879_RS00650	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AC879_RS00660	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AC879_RS00680	COG1609	Transcriptional regulator
AC879_RS00690	COG0154	amidase activity
AC879_RS00695	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AC879_RS00705	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AC879_RS00715	COG0583	DNA-binding transcription factor activity
AC879_RS00730	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AC879_RS00735	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AC879_RS00750	COG1802	Transcriptional regulator
AC879_RS00765	COG1024	Enoyl-CoA hydratase
AC879_RS00775	COG3181	Tripartite tricarboxylate transporter family receptor
AC879_RS00790	COG1984	allophanate hydrolase subunit 2
AC879_RS00795	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AC879_RS00805	COG0583	DNA-binding transcription factor activity
AC879_RS00810	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AC879_RS00820	COG5002	protein histidine kinase activity
AC879_RS00830	COG5002	protein histidine kinase activity
AC879_RS00835	COG0745	RESPONSE REGULATOR receiver
AC879_RS00840	COG2226	methyltransferase
AC879_RS00855	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AC879_RS00875	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AC879_RS00885	COG0513	Belongs to the DEAD box helicase family
AC879_RS00890	COG1280	lysine exporter protein (LysE YggA)
AC879_RS00895	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AC879_RS00930	COG1054	Belongs to the UPF0176 family
AC879_RS00935	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AC879_RS00935	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AC879_RS00945	COG0489	protein tyrosine kinase activity
AC879_RS00960	COG0717	Belongs to the dCTP deaminase family
AC879_RS00990	COG2081	HI0933 family
AC879_RS01000	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AC879_RS01010	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AC879_RS01015	COG0509	glycine decarboxylation via glycine cleavage system
AC879_RS01020	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AC879_RS01020	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AC879_RS01060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AC879_RS01075	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AC879_RS01085	COG1414	Transcriptional regulator
AC879_RS01090	COG1028	Short-chain dehydrogenase reductase Sdr
AC879_RS01095	COG2031	fatty acid transporter
AC879_RS01100	COG1250	3-hydroxyacyl-CoA dehydrogenase
AC879_RS01110	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AC879_RS01115	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AC879_RS01125	COG4257	antibiotic catabolic process
AC879_RS01150	COG1012	belongs to the aldehyde dehydrogenase family
AC879_RS01155	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AC879_RS01160	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AC879_RS01185	COG1028	Short-chain dehydrogenase reductase Sdr
AC879_RS01195	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AC879_RS01210	COG2188	Transcriptional regulator
AC879_RS01215	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AC879_RS01240	COG0617	tRNA 3'-terminal CCA addition
AC879_RS01255	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AC879_RS01260	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AC879_RS01265	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AC879_RS01270	COG0586	Pfam SNARE associated Golgi protein
AC879_RS01275	COG0860	N-Acetylmuramoyl-L-alanine amidase
AC879_RS01280	COG0802	atpase or kinase
AC879_RS01285	COG0114	fumarate hydratase activity
AC879_RS01295	COG3181	Tripartite tricarboxylate transporter family receptor
AC879_RS01305	COG0405	Gamma-glutamyltransferase
AC879_RS01310	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AC879_RS01320	COG1960	acyl-CoA dehydrogenase activity
AC879_RS01345	COG1294	oxidase, subunit
AC879_RS01355	COG4988	ABC transporter
AC879_RS01360	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AC879_RS01365	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AC879_RS01380	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AC879_RS01410	COG2969	positive regulation of protein catabolic process
AC879_RS01415	COG0625	glutathione transferase activity
AC879_RS01420	COG2857	Cytochrome c1
AC879_RS01425	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AC879_RS01430	COG0723	plastoquinol--plastocyanin reductase activity
AC879_RS01435	COG1970	mechanosensitive ion channel activity
AC879_RS01440	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AC879_RS01455	COG2808	Putative FMN-binding domain
AC879_RS01460	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AC879_RS01465	COG0747	negative chemotaxis
AC879_RS01470	COG0657	acetylesterase activity
AC879_RS01480	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AC879_RS01485	COG2207	Transcriptional regulator
AC879_RS01490	COG0129	dihydroxy-acid dehydratase activity
AC879_RS01495	COG2814	Major facilitator Superfamily
AC879_RS01500	COG0583	DNA-binding transcription factor activity
AC879_RS01510	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
AC879_RS01580	COG1024	Enoyl-CoA hydratase
AC879_RS01585	COG1960	acyl-CoA dehydrogenase activity
AC879_RS01610	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AC879_RS01615	COG0352	thiamine-phosphate diphosphorylase activity
AC879_RS01630	COG1678	Uncharacterized ACR, COG1678
AC879_RS01635	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AC879_RS01640	COG0540	Belongs to the ATCase OTCase family
AC879_RS01655	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AC879_RS01665	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AC879_RS01700	COG1234	tRNA 3'-trailer cleavage
AC879_RS01720	COG3064	Membrane
AC879_RS01750	COG1683	Conserved Protein
AC879_RS01755	COG1120	ATPase activity
AC879_RS01760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AC879_RS01765	COG4558	Periplasmic binding protein
AC879_RS01770	COG3720	iron ion transport
AC879_RS01780	COG3712	iron ion homeostasis
AC879_RS01785	COG1595	DNA-templated transcription, initiation
AC879_RS01820	COG1802	Transcriptional regulator
AC879_RS01830	COG3069	C4-dicarboxylate transmembrane transporter activity
AC879_RS01840	COG1012	belongs to the aldehyde dehydrogenase family
AC879_RS01875	COG2860	membrane
AC879_RS01880	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AC879_RS01885	COG0708	Exodeoxyribonuclease III
AC879_RS01890	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AC879_RS01895	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AC879_RS01900	COG0154	amidase activity
AC879_RS01905	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AC879_RS01910	COG1077	Cell shape determining protein MreB Mrl
AC879_RS01915	COG1792	Involved in formation and maintenance of cell shape
AC879_RS01925	COG0768	penicillin binding
AC879_RS01930	COG0772	Belongs to the SEDS family
AC879_RS01935	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AC879_RS01940	COG0471	metal ion transport
AC879_RS01945	COG1309	transcriptional regulator
AC879_RS01955	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AC879_RS01970	COG2823	Periplasmic or secreted lipoprotein
AC879_RS01975	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AC879_RS01990	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AC879_RS02010	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AC879_RS02020	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AC879_RS02040	COG0492	ferredoxin-NADP+ reductase activity
AC879_RS02050	COG3181	Tripartite tricarboxylate transporter family receptor
AC879_RS02055	COG1250	3-hydroxyacyl-CoA dehydrogenase
AC879_RS02055	COG1024	Enoyl-CoA hydratase
AC879_RS02060	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AC879_RS02065	COG0028	Belongs to the TPP enzyme family
AC879_RS02090	COG3181	Tripartite tricarboxylate transporter family receptor
AC879_RS02100	COG0697	spore germination
AC879_RS02130	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AC879_RS02135	COG0463	Glycosyl transferase, family 2
AC879_RS02155	COG0786	glutamate:sodium symporter activity
AC879_RS02165	COG2031	fatty acid transporter
AC879_RS02180	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AC879_RS02185	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AC879_RS02195	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AC879_RS02210	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AC879_RS02220	COG1285	pathogenesis
AC879_RS02225	COG1253	flavin adenine dinucleotide binding
AC879_RS02230	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AC879_RS02235	COG1024	Enoyl-CoA hydratase
AC879_RS02240	COG3181	Tripartite tricarboxylate transporter family receptor
AC879_RS02245	COG0583	DNA-binding transcription factor activity
AC879_RS02250	COG1960	acyl-CoA dehydrogenase activity
AC879_RS02260	COG0183	Belongs to the thiolase family
AC879_RS02280	COG0583	DNA-binding transcription factor activity
AC879_RS02285	COG1278	Cold shock
AC879_RS02295	COG1802	Transcriptional regulator
AC879_RS02300	COG1012	belongs to the aldehyde dehydrogenase family
AC879_RS02305	COG2031	fatty acid transporter
AC879_RS02310	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AC879_RS02310	COG1017	nitric oxide dioxygenase activity
AC879_RS02315	COG0251	oxidation-reduction process
AC879_RS02335	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AC879_RS02345	COG0583	DNA-binding transcription factor activity
AC879_RS02350	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AC879_RS02360	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AC879_RS02365	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AC879_RS02370	COG0546	phosphoglycolate phosphatase activity
AC879_RS02380	COG1530	ribonuclease E activity
AC879_RS02395	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AC879_RS02400	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AC879_RS02405	COG0159	tryptophan synthase activity
AC879_RS02410	COG0133	tryptophan synthase activity
AC879_RS02420	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AC879_RS02425	COG3228	Belongs to the MtfA family
AC879_RS02435	COG0251	oxidation-reduction process
AC879_RS02440	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AC879_RS02445	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AC879_RS02460	COG2878	Part of a membrane complex involved in electron transport
AC879_RS02465	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AC879_RS02500	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AC879_RS02520	COG1268	BioY protein
AC879_RS02525	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AC879_RS02530	COG1122	ATPase activity
AC879_RS02535	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AC879_RS02550	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AC879_RS02555	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AC879_RS02565	COG1196	nuclear chromosome segregation
AC879_RS02570	COG0477	Major facilitator Superfamily
AC879_RS02575	COG1573	uracil-dna glycosylase
AC879_RS02580	COG1214	PFAM Peptidase M22, glycoprotease
AC879_RS02605	COG0450	alkyl hydroperoxide reductase
AC879_RS02610	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AC879_RS02620	COG2223	nitrite transmembrane transporter activity
AC879_RS02630	COG2186	Transcriptional regulator
AC879_RS02650	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AC879_RS02660	COG0583	DNA-binding transcription factor activity
AC879_RS02670	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AC879_RS02675	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AC879_RS02680	COG0137	argininosuccinate synthase activity
AC879_RS02685	COG3158	transport of potassium into the cell
AC879_RS02690	COG0642	Histidine kinase
AC879_RS02720	COG0776	regulation of translation
AC879_RS02725	COG3128	pkhd-type hydroxylase
AC879_RS02735	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AC879_RS02740	COG0557	exoribonuclease II activity
AC879_RS02765	COG0679	Auxin Efflux Carrier
AC879_RS02770	COG2391	methyltransferase activity
AC879_RS02775	COG0069	glutamate synthase activity
AC879_RS02785	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AC879_RS02795	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
AC879_RS02800	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AC879_RS02835	COG3706	GGDEF domain
AC879_RS02855	COG1053	succinate dehydrogenase
AC879_RS02860	COG0583	DNA-binding transcription factor activity
AC879_RS02870	COG1053	succinate dehydrogenase
AC879_RS02890	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AC879_RS02895	COG0459	protein refolding
AC879_RS02900	COG3468	outer membrane autotransporter barrel domain protein
AC879_RS02915	COG1252	NADH dehydrogenase
AC879_RS02920	COG0284	orotidine-5'-phosphate decarboxylase activity
AC879_RS02925	COG1058	Belongs to the CinA family
AC879_RS02925	COG1546	Belongs to the CinA family
AC879_RS02930	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AC879_RS02940	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AC879_RS02945	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AC879_RS02980	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AC879_RS02985	COG3639	organic phosphonate transmembrane transporter activity
AC879_RS02990	COG3639	organic phosphonate transmembrane transporter activity
AC879_RS03010	COG0742	ribosomal rna small subunit methyltransferase
AC879_RS03015	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AC879_RS03020	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AC879_RS03025	COG3135	benzoate transporter
AC879_RS03040	COG0640	Transcriptional regulator
AC879_RS03070	COG4172	Belongs to the ABC transporter superfamily
AC879_RS03075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AC879_RS03080	COG0601	transmembrane transport
AC879_RS03090	COG0280	phosphate acetyltransferase
AC879_RS03090	COG0281	malic enzyme
AC879_RS03150	COG0583	DNA-binding transcription factor activity
AC879_RS03160	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AC879_RS03165	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AC879_RS03170	COG0167	dihydroorotate dehydrogenase activity
AC879_RS03190	COG1414	Transcriptional regulator
AC879_RS03195	COG1546	Belongs to the CinA family
AC879_RS03195	COG1058	Belongs to the CinA family
AC879_RS03215	COG0513	Belongs to the DEAD box helicase family
AC879_RS03245	COG0429	hydrolase of the alpha beta-hydrolase fold
AC879_RS03250	COG4783	chaperone-mediated protein folding
AC879_RS03265	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AC879_RS03290	COG0006	proline dipeptidase activity
AC879_RS03300	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AC879_RS03320	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AC879_RS03325	COG0632	four-way junction helicase activity
AC879_RS03340	COG2255	four-way junction helicase activity
AC879_RS03345	COG0514	ATP-dependent DNA helicase (RecQ)
AC879_RS03360	COG0288	reversible hydration of carbon dioxide
AC879_RS03365	COG0154	amidase activity
AC879_RS03375	COG4211	Belongs to the binding-protein-dependent transport system permease family
AC879_RS03405	COG1464	Belongs to the NlpA lipoprotein family
AC879_RS03550	COG1196	nuclear chromosome segregation
AC879_RS03620	COG2135	peptidase activity
AC879_RS03635	COG0494	nUDIX hydrolase
AC879_RS03640	COG0442	prolyl-tRNA aminoacylation
AC879_RS03645	COG0824	Thioesterase
AC879_RS03650	COG0811	peptide transport
AC879_RS03655	COG0848	biopolymer transport protein
AC879_RS03665	COG0823	Involved in the tonB-independent uptake of proteins
AC879_RS03680	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AC879_RS03685	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AC879_RS03720	COG0700	Nucleoside recognition
AC879_RS03725	COG0469	pyruvate kinase activity
AC879_RS03730	COG1929	Belongs to the glycerate kinase type-1 family
AC879_RS03735	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AC879_RS03740	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AC879_RS03745	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AC879_RS03755	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AC879_RS03765	COG2154	pterin-4-alpha-carbinolamine dehydratase
AC879_RS03790	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AC879_RS03795	COG0154	amidase activity
AC879_RS03805	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AC879_RS03810	COG0601	transmembrane transport
AC879_RS03815	COG0747	negative chemotaxis
AC879_RS03835	COG0019	diaminopimelate decarboxylase activity
AC879_RS03850	COG2353	YceI-like domain
AC879_RS03855	COG4774	siderophore transport
AC879_RS03860	COG3712	iron ion homeostasis
AC879_RS03900	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AC879_RS03905	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AC879_RS03910	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AC879_RS03915	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AC879_RS03925	COG0142	geranyltranstransferase activity
AC879_RS03935	COG0583	DNA-binding transcription factor activity
AC879_RS03945	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
AC879_RS03950	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AC879_RS03965	COG2994	toxin metabolic process
AC879_RS03975	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
AC879_RS03980	COG2274	protein secretion by the type I secretion system
AC879_RS03985	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AC879_RS03990	COG1538	Outer membrane efflux protein
AC879_RS04005	COG0765	amino acid transport
AC879_RS04010	COG0765	amino acid transport
AC879_RS04015	COG1126	abc transporter atp-binding protein
AC879_RS04035	COG1028	Short-chain dehydrogenase reductase Sdr
AC879_RS04045	COG1802	Transcriptional regulator
AC879_RS04055	COG1802	Transcriptional regulator
AC879_RS04065	COG0318	PFAM AMP-dependent synthetase and ligase
AC879_RS04075	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AC879_RS04095	COG0028	Belongs to the TPP enzyme family
AC879_RS04115	COG0308	aminopeptidase N
AC879_RS04120	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AC879_RS04130	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AC879_RS04135	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AC879_RS04140	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AC879_RS04145	COG0560	Phosphoserine phosphatase
AC879_RS04150	COG0583	DNA-binding transcription factor activity
AC879_RS04155	COG3181	Tripartite tricarboxylate transporter family receptor
AC879_RS04160	COG0028	Belongs to the TPP enzyme family
AC879_RS04175	COG4774	siderophore transport
AC879_RS04180	COG4774	siderophore transport
AC879_RS04190	COG1007	ATP synthesis coupled electron transport
AC879_RS04205	COG0713	ATP synthesis coupled electron transport
AC879_RS04215	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AC879_RS04220	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AC879_RS04225	COG1034	ATP synthesis coupled electron transport
AC879_RS04235	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AC879_RS04240	COG0649	NAD binding
AC879_RS04245	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AC879_RS04250	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AC879_RS04255	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AC879_RS04260	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AC879_RS04290	COG0671	phosphoesterase, PA-phosphatase related
AC879_RS04300	COG1597	lipid kinase activity
AC879_RS04305	COG0583	DNA-binding transcription factor activity
AC879_RS04310	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AC879_RS04320	COG1733	regulation of RNA biosynthetic process
AC879_RS04325	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AC879_RS04330	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AC879_RS04345	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
AC879_RS04365	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AC879_RS04385	COG3608	succinylglutamate desuccinylase aspartoacylase
AC879_RS04390	COG0626	cystathionine gamma-synthase activity
AC879_RS04395	COG0583	DNA-binding transcription factor activity
AC879_RS04430	COG3799	methylaspartate ammonia-lyase activity
AC879_RS04440	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AC879_RS04450	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AC879_RS04455	COG0149	triose-phosphate isomerase activity
AC879_RS04475	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AC879_RS04490	COG1185	polyribonucleotide nucleotidyltransferase activity
AC879_RS04495	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AC879_RS04510	COG1183	phosphatidylcholine synthase activity
AC879_RS04515	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AC879_RS04520	COG0440	acetolactate synthase activity
AC879_RS04525	COG0028	Belongs to the TPP enzyme family
AC879_RS04540	COG5265	(ABC) transporter
AC879_RS04545	COG0500	methyltransferase
AC879_RS04565	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
AC879_RS04585	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AC879_RS04595	COG0511	ligase activity, forming carbon-carbon bonds
AC879_RS04620	COG2188	Transcriptional regulator
AC879_RS04625	COG0439	Biotin carboxylase
AC879_RS04630	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AC879_RS04675	COG5265	(ABC) transporter
AC879_RS04685	COG0667	Aldo Keto reductase
AC879_RS04700	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AC879_RS04740	COG0583	DNA-binding transcription factor activity
AC879_RS04765	COG2814	Major facilitator Superfamily
AC879_RS04775	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AC879_RS04790	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AC879_RS04800	COG0287	Prephenate dehydrogenase
AC879_RS04805	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AC879_RS04810	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AC879_RS04830	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AC879_RS04835	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AC879_RS04840	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AC879_RS04845	COG1555	photosystem II stabilization
AC879_RS04845	COG1596	polysaccharide export
AC879_RS04860	COG2951	lytic endotransglycosylase activity
AC879_RS04865	COG0123	including yeast histone deacetylase and acetoin utilization protein
AC879_RS04880	COG1960	acyl-CoA dehydrogenase activity
AC879_RS04885	COG0450	alkyl hydroperoxide reductase
AC879_RS04900	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AC879_RS04905	COG4208	sulfate ABC transporter
AC879_RS04910	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AC879_RS04940	COG0335	large ribosomal subunit rRNA binding
AC879_RS04955	COG0667	Aldo Keto reductase
AC879_RS04965	COG2814	Major facilitator Superfamily
AC879_RS04970	COG3161	chorismate lyase activity
AC879_RS04975	COG1187	pseudouridine synthase activity
AC879_RS04985	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AC879_RS05005	COG1999	signal sequence binding
AC879_RS05010	COG0339	signal peptide processing
AC879_RS05015	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AC879_RS05020	COG4566	intracellular signal transduction
AC879_RS05030	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AC879_RS05035	COG0508	dehydrogenase complex catalyzes the overall conversion of
AC879_RS05040	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AC879_RS05045	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AC879_RS05055	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AC879_RS05060	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AC879_RS05065	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AC879_RS05070	COG0126	phosphoglycerate kinase activity
AC879_RS05075	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AC879_RS05080	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AC879_RS05095	COG0625	glutathione transferase activity
AC879_RS05130	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AC879_RS05140	COG0521	Mo-molybdopterin cofactor biosynthetic process
AC879_RS05150	COG0739	heme binding
AC879_RS05160	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AC879_RS05195	COG0745	RESPONSE REGULATOR receiver
AC879_RS05210	COG0840	transmembrane signaling receptor activity
AC879_RS05220	COG2201	protein-glutamate methylesterase activity
AC879_RS05225	COG0745	RESPONSE REGULATOR receiver
AC879_RS05230	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AC879_RS05255	COG0667	Aldo Keto reductase
AC879_RS05265	COG4535	Mg2 and Co2 transporter CorC
AC879_RS05270	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AC879_RS05275	COG1702	phosphate starvation-inducible protein PhoH
AC879_RS05280	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AC879_RS05295	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AC879_RS05300	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AC879_RS05305	COG1862	Preprotein translocase
AC879_RS05310	COG0343	queuine tRNA-ribosyltransferase activity
AC879_RS05315	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AC879_RS05320	COG2027	D-alanyl-D-alanine carboxypeptidase
AC879_RS05325	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AC879_RS05340	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AC879_RS05340	COG1648	precorrin-2 dehydrogenase activity
AC879_RS05365	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AC879_RS05370	COG0741	lytic transglycosylase activity
AC879_RS05375	COG0436	Aminotransferase
AC879_RS05385	COG0280	phosphate acetyltransferase
AC879_RS05385	COG0281	malic enzyme
AC879_RS05395	COG2732	(Barnase) inhibitor
AC879_RS05410	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AC879_RS05435	COG0248	Ppx GppA phosphatase
AC879_RS05445	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AC879_RS05455	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AC879_RS05460	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AC879_RS05465	COG1534	Rna-binding protein
AC879_RS05495	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AC879_RS05510	COG1295	ribonuclease BN
AC879_RS05520	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AC879_RS05525	COG0745	RESPONSE REGULATOR receiver
AC879_RS05530	COG2205	protein histidine kinase activity
AC879_RS05565	COG1022	Amp-dependent synthetase and ligase
AC879_RS05580	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AC879_RS05585	COG1028	Short-chain dehydrogenase reductase Sdr
AC879_RS05595	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AC879_RS05610	COG1136	(ABC) transporter
AC879_RS05615	COG0084	hydrolase, TatD family'
AC879_RS05645	COG0658	competence protein
AC879_RS05645	COG2333	competence protein COMEC
AC879_RS05655	COG0613	PHP domain protein
AC879_RS05670	COG3539	Fimbrial protein
AC879_RS05675	COG0281	malic enzyme
AC879_RS05675	COG0280	phosphate acetyltransferase
AC879_RS05685	COG1522	sequence-specific DNA binding
AC879_RS05695	COG0567	Dehydrogenase, E1 component
AC879_RS05700	COG0508	dehydrogenase complex catalyzes the overall conversion of
AC879_RS05705	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AC879_RS05710	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AC879_RS05715	COG1028	Short-chain dehydrogenase reductase Sdr
AC879_RS05720	COG0583	DNA-binding transcription factor activity
AC879_RS05730	COG3181	Tripartite tricarboxylate transporter family receptor
AC879_RS05755	COG0180	Tryptophanyl-tRNA synthetase
AC879_RS05760	COG2183	response to ionizing radiation
AC879_RS05765	COG1199	ATP-dependent helicase activity
AC879_RS05775	COG0564	pseudouridine synthase activity
AC879_RS05785	COG3243	poly(R)-hydroxyalkanoic acid synthase
AC879_RS05790	COG1028	Short-chain dehydrogenase reductase Sdr
AC879_RS05795	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
AC879_RS05810	COG0672	)-iron permease
AC879_RS05850	COG0583	DNA-binding transcription factor activity
AC879_RS05860	COG2814	Major facilitator Superfamily
AC879_RS05875	COG1619	proteins homologs of microcin C7 resistance protein MccF
AC879_RS05890	COG2084	Dehydrogenase
AC879_RS05895	COG3181	Tripartite tricarboxylate transporter family receptor
AC879_RS05920	COG2988	succinylglutamate desuccinylase activity
AC879_RS05950	COG0765	amino acid transport
AC879_RS05955	COG0765	amino acid transport
AC879_RS05960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AC879_RS05995	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AC879_RS06000	COG1595	DNA-templated transcription, initiation
AC879_RS06010	COG3530	Putative quorum-sensing-regulated virulence factor
AC879_RS06015	COG0494	nUDIX hydrolase
AC879_RS06030	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AC879_RS06035	COG0542	response to heat
AC879_RS06050	COG3468	outer membrane autotransporter barrel domain protein
AC879_RS06055	COG3468	outer membrane autotransporter barrel domain protein
AC879_RS06065	COG5441	Belongs to the UPF0261 family
AC879_RS06070	COG5564	TIM-barrel signal transduction protein
AC879_RS06085	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AC879_RS06100	COG1477	protein flavinylation
AC879_RS06120	COG1131	(ABC) transporter
AC879_RS06125	COG0842	Transport permease protein
AC879_RS06135	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AC879_RS06140	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
AC879_RS06140	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
AC879_RS06145	COG1562	ergosterol biosynthetic process
AC879_RS06150	COG1562	ergosterol biosynthetic process
AC879_RS06155	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AC879_RS06160	COG1028	Short-chain dehydrogenase reductase Sdr
AC879_RS06180	COG2304	oxidoreductase activity
AC879_RS06200	COG0534	Mate efflux family protein
AC879_RS06210	COG0254	rRNA binding
AC879_RS06215	COG3483	tryptophan 2,3-dioxygenase activity
AC879_RS06220	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AC879_RS06225	COG2003	Belongs to the UPF0758 family
AC879_RS06230	COG1047	Peptidyl-prolyl cis-trans
AC879_RS06235	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AC879_RS06240	COG0625	glutathione transferase activity
AC879_RS06260	COG0523	cobalamin synthesis protein
AC879_RS06270	COG0583	DNA-binding transcription factor activity
AC879_RS06280	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AC879_RS06285	COG1187	pseudouridine synthase activity
AC879_RS06290	COG0779	Required for maturation of 30S ribosomal subunits
AC879_RS06295	COG0195	Participates in both transcription termination and antitermination
AC879_RS06295	COG2251	uridine kinase activity
AC879_RS06300	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AC879_RS06305	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AC879_RS06310	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AC879_RS06330	COG1611	Belongs to the LOG family
AC879_RS06345	COG0412	Dienelactone hydrolase
AC879_RS06350	COG1283	sodium-dependent phosphate transmembrane transporter activity
AC879_RS06355	COG1760	l-serine dehydratase
AC879_RS06360	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AC879_RS06365	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AC879_RS06375	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AC879_RS06400	COG2311	Membrane
AC879_RS06410	COG0697	spore germination
AC879_RS06425	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AC879_RS06440	COG0559	Belongs to the binding-protein-dependent transport system permease family
AC879_RS06455	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AC879_RS06465	COG1653	transport
AC879_RS06470	COG1175	transmembrane transport
AC879_RS06475	COG0395	ABC-type sugar transport system, permease component
AC879_RS06480	COG3842	ATPase activity
AC879_RS06505	COG2363	Small membrane protein
AC879_RS06520	COG1464	Belongs to the NlpA lipoprotein family
AC879_RS06530	COG0688	phosphatidylethanolamine metabolic process
AC879_RS06555	COG0625	glutathione transferase activity
AC879_RS06560	COG0386	Belongs to the glutathione peroxidase family
AC879_RS06580	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AC879_RS06610	COG2259	Doxx family
AC879_RS06625	COG0667	Aldo Keto reductase
AC879_RS06655	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AC879_RS06675	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AC879_RS06685	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AC879_RS06725	COG0392	lysyltransferase activity
AC879_RS06740	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AC879_RS06745	COG3568	Endonuclease Exonuclease Phosphatase
AC879_RS06755	COG1695	Transcriptional regulator
AC879_RS06775	COG0583	DNA-binding transcription factor activity
AC879_RS06790	COG1802	Transcriptional regulator
AC879_RS06800	COG3181	Tripartite tricarboxylate transporter family receptor
AC879_RS06810	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AC879_RS06825	COG0066	3-isopropylmalate dehydratase activity
AC879_RS06835	COG3181	Tripartite tricarboxylate transporter family receptor
AC879_RS06840	COG4948	Mandelate Racemase Muconate Lactonizing
AC879_RS06855	COG1126	abc transporter atp-binding protein
AC879_RS06860	COG0765	amino acid transport
AC879_RS06865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AC879_RS06885	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AC879_RS06910	COG1815	bacterial-type flagellum-dependent cell motility
AC879_RS06915	COG1558	bacterial-type flagellum-dependent cell motility
AC879_RS06925	COG1749	Flagellar hook protein flgE
AC879_RS06940	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AC879_RS06945	COG1706	bacterial-type flagellum-dependent cell motility
AC879_RS06955	COG1256	bacterial-type flagellum assembly
AC879_RS06965	COG0840	transmembrane signaling receptor activity
AC879_RS06970	COG0840	transmembrane signaling receptor activity
AC879_RS06975	COG0840	transmembrane signaling receptor activity
AC879_RS06995	COG1338	Plays a role in the flagellum-specific transport system
AC879_RS07015	COG1580	Controls the rotational direction of flagella during chemotaxis
AC879_RS07040	COG1157	protein secretion by the type III secretion system
AC879_RS07050	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AC879_RS07060	COG1677	Flagellar hook-basal body complex protein FliE
AC879_RS07070	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AC879_RS07105	COG0285	dihydrofolate synthase activity
AC879_RS07135	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AC879_RS07140	COG0024	Methionine aminopeptidase
AC879_RS07145	COG0052	Belongs to the universal ribosomal protein uS2 family
AC879_RS07150	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AC879_RS07155	COG0528	UMP kinase activity
AC879_RS07160	COG0233	cytoplasmic translational termination
AC879_RS07165	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AC879_RS07175	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AC879_RS07180	COG0750	zinc metalloprotease
AC879_RS07185	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AC879_RS07190	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
AC879_RS07195	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AC879_RS07200	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AC879_RS07210	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AC879_RS07215	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AC879_RS07220	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AC879_RS07225	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AC879_RS07235	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AC879_RS07235	COG0519	Catalyzes the synthesis of GMP from XMP
AC879_RS07250	COG0330	HflC and HflK could
AC879_RS07255	COG3706	GGDEF domain
AC879_RS07260	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AC879_RS07270	COG2867	negative regulation of translational initiation
AC879_RS07280	COG1960	acyl-CoA dehydrogenase activity
AC879_RS07285	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AC879_RS07315	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AC879_RS07320	COG0505	Belongs to the CarA family
AC879_RS07325	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AC879_RS07335	COG0406	alpha-ribazole phosphatase activity
AC879_RS07345	COG3842	ATPase activity
AC879_RS07365	COG5001	Diguanylate cyclase
AC879_RS07370	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AC879_RS07380	COG1763	Mo-molybdopterin cofactor biosynthetic process
AC879_RS07385	COG0303	'Molybdopterin
AC879_RS07390	COG0746	molybdenum cofactor guanylyltransferase activity
AC879_RS07395	COG0489	protein tyrosine kinase activity
AC879_RS07425	COG3383	formate dehydrogenase (NAD+) activity
AC879_RS07425	COG0243	molybdopterin cofactor binding
AC879_RS07430	COG0437	4 iron, 4 sulfur cluster binding
AC879_RS07460	COG1122	ATPase activity
AC879_RS07470	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AC879_RS07475	COG0066	3-isopropylmalate dehydratase activity
AC879_RS07480	COG0473	3-isopropylmalate dehydrogenase activity
AC879_RS07485	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AC879_RS07495	COG0101	tRNA pseudouridine synthase activity
AC879_RS07500	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AC879_RS07515	COG0135	phosphoribosylanthranilate isomerase activity
AC879_RS07530	COG3022	response to hydroperoxide
AC879_RS07540	COG1289	transmembrane transporter activity
AC879_RS07560	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AC879_RS07570	COG2197	response regulator
AC879_RS07575	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AC879_RS07580	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AC879_RS07585	COG0189	ligase activity
AC879_RS07595	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AC879_RS07600	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AC879_RS07610	COG1764	response to oxidative stress
AC879_RS07615	COG2423	ornithine cyclodeaminase activity
AC879_RS07625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AC879_RS07630	COG0765	amino acid transport
AC879_RS07635	COG0765	amino acid transport
AC879_RS07640	COG1126	abc transporter atp-binding protein
AC879_RS07695	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AC879_RS07705	COG2944	sequence-specific DNA binding
AC879_RS07715	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AC879_RS07720	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AC879_RS07725	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AC879_RS07730	COG0009	L-threonylcarbamoyladenylate synthase
AC879_RS07735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AC879_RS07740	COG1414	Transcriptional regulator
AC879_RS07755	COG0765	amino acid transport
AC879_RS07760	COG1126	abc transporter atp-binding protein
AC879_RS07765	COG0028	Belongs to the TPP enzyme family
AC879_RS07780	COG0028	Belongs to the TPP enzyme family
AC879_RS07785	COG0583	DNA-binding transcription factor activity
AC879_RS07790	COG4974	Belongs to the 'phage' integrase family
AC879_RS07795	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AC879_RS07800	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
AC879_RS07815	COG1686	Belongs to the peptidase S11 family
AC879_RS07825	COG2814	Major facilitator Superfamily
AC879_RS07835	COG1074	ATP-dependent DNA helicase activity
AC879_RS07850	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AC879_RS07855	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AC879_RS07860	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AC879_RS07880	COG2321	neutral zinc metallopeptidase
AC879_RS07885	COG0009	L-threonylcarbamoyladenylate synthase
AC879_RS07930	COG3360	Dodecin
AC879_RS07935	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AC879_RS07940	COG2850	peptidyl-arginine hydroxylation
AC879_RS07945	COG3539	Fimbrial protein
AC879_RS07950	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AC879_RS07955	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AC879_RS07975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AC879_RS07980	COG0765	amino acid transport
AC879_RS07985	COG1126	abc transporter atp-binding protein
AC879_RS07990	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AC879_RS07995	COG1758	RNA polymerase activity
AC879_RS08000	COG0194	GDP metabolic process
AC879_RS08005	COG3258	Cytochrome c
AC879_RS08010	COG2863	cytochrome
AC879_RS08015	COG1028	Short-chain dehydrogenase reductase Sdr
AC879_RS08020	COG0791	NLP P60 protein
AC879_RS08025	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AC879_RS08045	COG1561	YicC-like family, N-terminal region
AC879_RS08050	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AC879_RS08065	COG0840	transmembrane signaling receptor activity
AC879_RS08070	COG2200	EAL domain
AC879_RS08070	COG2199	diguanylate cyclase activity
AC879_RS08075	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AC879_RS08085	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AC879_RS08090	COG0174	glutamine synthetase
AC879_RS08100	COG2204	response regulator
AC879_RS08105	COG0583	DNA-binding transcription factor activity
AC879_RS08110	COG1741	Belongs to the pirin family
AC879_RS08115	COG1741	Belongs to the pirin family
AC879_RS08125	COG3842	ATPase activity
AC879_RS08130	COG1178	ABC-type Fe3 transport system permease component
AC879_RS08135	COG1840	ABC-type Fe3 transport system, periplasmic component
AC879_RS08145	COG0583	DNA-binding transcription factor activity
AC879_RS08155	COG0656	L-ascorbic acid biosynthetic process
AC879_RS08170	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AC879_RS08175	COG0583	DNA-binding transcription factor activity
AC879_RS08190	COG0783	Belongs to the Dps family
AC879_RS08210	COG0463	Glycosyl transferase, family 2
AC879_RS08230	COG0438	transferase activity, transferring glycosyl groups
AC879_RS08245	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AC879_RS08270	COG0300	oxidoreductase activity
AC879_RS08315	COG0861	Integral membrane protein TerC family
AC879_RS08320	COG1028	Short-chain dehydrogenase reductase Sdr
AC879_RS08340	COG0714	Associated with various cellular activities
AC879_RS08375	COG3119	arylsulfatase activity
AC879_RS08400	COG2197	response regulator
AC879_RS08410	COG2944	sequence-specific DNA binding
AC879_RS08415	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
AC879_RS08420	COG0625	glutathione transferase activity
AC879_RS08450	COG0179	Fumarylacetoacetate (FAA) hydrolase
AC879_RS08455	COG1028	Short-chain dehydrogenase reductase Sdr
AC879_RS08500	COG0431	NADPH-dependent FMN reductase
AC879_RS08530	COG1028	Short-chain dehydrogenase reductase Sdr
AC879_RS08535	COG0583	DNA-binding transcription factor activity
AC879_RS08550	COG3181	Tripartite tricarboxylate transporter family receptor
AC879_RS08555	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AC879_RS08555	COG2111	Na H antiporter
AC879_RS08560	COG1006	Multisubunit Na H antiporter MnhC subunit
AC879_RS08565	COG0651	ATP synthesis coupled electron transport
AC879_RS08570	COG1863	multisubunit Na H antiporter MnhE subunit
AC879_RS08575	COG2212	antiporter activity
AC879_RS08600	COG0590	tRNA wobble adenosine to inosine editing
AC879_RS08605	COG1619	proteins homologs of microcin C7 resistance protein MccF
AC879_RS08610	COG1024	Enoyl-CoA hydratase
AC879_RS08625	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AC879_RS08630	COG0488	(ABC) transporter
AC879_RS08665	COG1017	nitric oxide dioxygenase activity
AC879_RS08665	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AC879_RS08670	COG1959	2 iron, 2 sulfur cluster binding
AC879_RS08675	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AC879_RS08695	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AC879_RS08700	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AC879_RS08705	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AC879_RS08710	COG0084	hydrolase, TatD family'
AC879_RS08725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AC879_RS08735	COG1126	abc transporter atp-binding protein
AC879_RS08740	COG0010	Belongs to the arginase family
AC879_RS08745	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AC879_RS08750	COG1012	belongs to the aldehyde dehydrogenase family
AC879_RS08760	COG0028	Belongs to the TPP enzyme family
AC879_RS08770	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AC879_RS08770	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AC879_RS08780	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AC879_RS08795	COG3189	MarR family transcriptional regulator
AC879_RS08800	COG2010	Cytochrome c
AC879_RS08825	COG4336	lyase activity
AC879_RS08835	COG2205	protein histidine kinase activity
AC879_RS08835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AC879_RS08840	COG2197	response regulator
AC879_RS08845	COG3064	Membrane
AC879_RS08845	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
AC879_RS08845	COG3210	domain, Protein
AC879_RS08855	COG3121	Chaperone
AC879_RS08860	COG3188	usher protein
AC879_RS08865	COG3539	Fimbrial protein
AC879_RS08870	COG2831	hemolysin activation secretion protein
AC879_RS08885	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AC879_RS08910	COG0583	DNA-binding transcription factor activity
AC879_RS08935	COG0668	transmembrane transport
AC879_RS08955	COG0483	inositol monophosphate 1-phosphatase activity
AC879_RS08960	COG1253	flavin adenine dinucleotide binding
AC879_RS08965	COG1968	undecaprenyl-diphosphatase activity
AC879_RS08970	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AC879_RS08985	COG0215	cysteine-tRNA ligase activity
AC879_RS08995	COG0825	malonyl-CoA metabolic process
AC879_RS09005	COG0037	tRNA processing
AC879_RS09010	COG0527	aspartate kinase activity
AC879_RS09035	COG1250	3-hydroxyacyl-CoA dehydrogenase
AC879_RS09040	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AC879_RS09040	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AC879_RS09055	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AC879_RS09060	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
AC879_RS09065	COG1028	Short-chain dehydrogenase reductase Sdr
AC879_RS09075	COG0583	DNA-binding transcription factor activity
AC879_RS09105	COG3842	ATPase activity
AC879_RS09115	COG0446	pyridine nucleotide-disulphide oxidoreductase
AC879_RS09115	COG1902	pentaerythritol trinitrate reductase activity
AC879_RS09120	COG1414	Transcriptional regulator
AC879_RS09125	COG1832	CoA-binding protein
AC879_RS09135	COG0251	oxidation-reduction process
AC879_RS09160	COG1902	pentaerythritol trinitrate reductase activity
AC879_RS09170	COG1215	transferase activity, transferring glycosyl groups
AC879_RS09175	COG0726	polysaccharide deacetylase
AC879_RS09175	COG1649	PFAM Uncharacterised BCR, COG1649
AC879_RS09195	COG1846	Transcriptional regulator
AC879_RS09200	COG2197	response regulator
AC879_RS09215	COG0166	Belongs to the GPI family
AC879_RS09220	COG1045	serine acetyltransferase
AC879_RS09230	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AC879_RS09235	COG0483	inositol monophosphate 1-phosphatase activity
AC879_RS09240	COG1012	belongs to the aldehyde dehydrogenase family
AC879_RS09245	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AC879_RS09260	COG0210	DNA helicase
AC879_RS09265	COG0598	Magnesium transport protein CorA
AC879_RS09275	COG0747	negative chemotaxis
AC879_RS09280	COG0601	transmembrane transport
AC879_RS09285	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AC879_RS09290	COG4172	Belongs to the ABC transporter superfamily
AC879_RS09295	COG1846	Transcriptional regulator
AC879_RS09345	COG4964	Belongs to the GSP D family
AC879_RS09385	COG2204	response regulator
AC879_RS09400	COG1595	DNA-templated transcription, initiation
AC879_RS09410	COG3474	cytochrome
AC879_RS09415	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AC879_RS09430	COG3384	dioxygenase
AC879_RS09435	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AC879_RS09460	COG2885	chlorophyll binding
AC879_RS09495	COG0697	spore germination
AC879_RS09500	COG0730	response to heat
AC879_RS09520	COG0583	DNA-binding transcription factor activity
AC879_RS09525	COG0427	acetyl-CoA hydrolase
AC879_RS09580	COG1250	3-hydroxyacyl-CoA dehydrogenase
AC879_RS09585	COG0154	amidase activity
AC879_RS09595	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AC879_RS09610	COG0495	leucyl-tRNA aminoacylation
AC879_RS09615	COG2814	Major facilitator Superfamily
AC879_RS09645	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AC879_RS09650	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AC879_RS09655	COG2814	Major facilitator Superfamily
AC879_RS09660	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AC879_RS09675	COG4176	ABC-type proline glycine betaine transport system permease component
AC879_RS09685	COG1942	4-Oxalocrotonate Tautomerase
AC879_RS09690	COG0183	Belongs to the thiolase family
AC879_RS09700	COG1802	Transcriptional regulator
AC879_RS09710	COG1024	Enoyl-CoA hydratase
AC879_RS09715	COG0318	PFAM AMP-dependent synthetase and ligase
AC879_RS09720	COG0318	PFAM AMP-dependent synthetase and ligase
AC879_RS09730	COG2032	superoxide dismutase activity
AC879_RS09745	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AC879_RS09770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AC879_RS09775	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AC879_RS09785	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AC879_RS09790	COG0736	holo-[acyl-carrier-protein] synthase activity
AC879_RS09795	COG1472	Belongs to the glycosyl hydrolase 3 family
AC879_RS09800	COG0322	excinuclease ABC activity
AC879_RS09805	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AC879_RS09820	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AC879_RS09820	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AC879_RS09825	COG2224	Isocitrate lyase
AC879_RS09845	COG0559	Belongs to the binding-protein-dependent transport system permease family
AC879_RS09855	COG4638	Rieske (2fe-2S)
AC879_RS09865	COG1024	Enoyl-CoA hydratase
AC879_RS09875	COG0633	Ferredoxin
AC879_RS09880	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AC879_RS09895	COG0183	Belongs to the thiolase family
AC879_RS09940	COG2346	COG2346, Truncated hemoglobins
AC879_RS10070	COG2207	Transcriptional regulator
AC879_RS10115	COG1132	(ABC) transporter
AC879_RS10140	COG0659	secondary active sulfate transmembrane transporter activity
AC879_RS10170	COG2169	Transcriptional regulator
AC879_RS10175	COG5507	3-demethylubiquinone-9 3-methyltransferase
AC879_RS10180	COG0384	phenazine biosynthesis protein PhzF
AC879_RS10185	COG0583	DNA-binding transcription factor activity
AC879_RS10190	COG2733	membrane
AC879_RS10205	COG1012	belongs to the aldehyde dehydrogenase family
AC879_RS10210	COG3284	Transcriptional regulator
AC879_RS10230	COG1380	Effector of murein hydrolase LrgA
AC879_RS10235	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AC879_RS10235	COG4106	trans-aconitate 2-methyltransferase activity
AC879_RS10245	COG0156	8-amino-7-oxononanoate synthase activity
AC879_RS10315	COG1131	(ABC) transporter
AC879_RS10320	COG0842	Transport permease protein
AC879_RS10325	COG0628	permease
AC879_RS10355	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AC879_RS10365	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AC879_RS10370	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AC879_RS10375	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AC879_RS10380	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AC879_RS10385	COG0330	HflC and HflK could
AC879_RS10390	COG0330	HflC and HflK could
AC879_RS10395	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AC879_RS10400	COG1923	regulation of RNA biosynthetic process
AC879_RS10405	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AC879_RS10410	COG1160	GTP binding
AC879_RS10415	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AC879_RS10420	COG2976	Protein conserved in bacteria
AC879_RS10425	COG0124	histidyl-tRNA synthetase
AC879_RS10430	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AC879_RS10440	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AC879_RS10445	COG0105	UTP biosynthetic process
AC879_RS10450	COG0525	valine-tRNA ligase activity
AC879_RS10465	COG0642	Histidine kinase
AC879_RS10485	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AC879_RS10490	COG0336	Belongs to the RNA methyltransferase TrmD family
AC879_RS10495	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AC879_RS10500	COG0228	four-way junction DNA binding
AC879_RS10510	COG0425	Belongs to the sulfur carrier protein TusA family
AC879_RS10515	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AC879_RS10560	COG0154	amidase activity
AC879_RS10565	COG4172	Belongs to the ABC transporter superfamily
AC879_RS10570	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AC879_RS10575	COG0601	transmembrane transport
AC879_RS10580	COG0747	negative chemotaxis
AC879_RS10610	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AC879_RS10620	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AC879_RS10635	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AC879_RS10640	COG3395	kinase activity
AC879_RS10655	COG1024	Enoyl-CoA hydratase
AC879_RS10675	COG0633	Ferredoxin
AC879_RS10680	COG0443	Heat shock 70 kDa protein
AC879_RS10685	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AC879_RS10690	COG0316	Belongs to the HesB IscA family
AC879_RS10695	COG0822	iron-sulfur transferase activity
AC879_RS10700	COG1104	cysteine desulfurase activity
AC879_RS10710	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AC879_RS10715	COG0556	nucleotide-excision repair
AC879_RS10725	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AC879_RS10730	COG3468	outer membrane autotransporter barrel domain protein
AC879_RS10760	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AC879_RS10775	COG1960	acyl-CoA dehydrogenase activity
AC879_RS10780	COG1028	Short-chain dehydrogenase reductase Sdr
AC879_RS10785	COG0183	Belongs to the thiolase family
AC879_RS10795	COG1024	Enoyl-CoA hydratase
AC879_RS10810	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AC879_RS10815	COG0583	DNA-binding transcription factor activity
AC879_RS10820	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AC879_RS10825	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AC879_RS10830	COG0740	serine-type endopeptidase activity
AC879_RS10835	COG0544	peptidyl-prolyl cis-trans isomerase activity
AC879_RS10855	COG1278	Cold shock
AC879_RS10890	COG2171	N-acyltransferase activity
AC879_RS10895	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AC879_RS10900	COG2890	protein-(glutamine-N5) methyltransferase activity
AC879_RS10905	COG0488	(ABC) transporter
AC879_RS10910	COG4771	TonB-dependent receptor
AC879_RS10915	COG0210	DNA helicase
AC879_RS10935	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AC879_RS10940	COG0196	riboflavin kinase activity
AC879_RS10945	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AC879_RS10950	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AC879_RS10955	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AC879_RS10965	COG1522	sequence-specific DNA binding
AC879_RS10985	COG2951	lytic endotransglycosylase activity
AC879_RS10990	COG2833	Protein of unknown function (DUF455)
AC879_RS11010	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AC879_RS11010	COG0189	ligase activity
AC879_RS11015	COG1181	Belongs to the D-alanine--D-alanine ligase family
AC879_RS11015	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AC879_RS11020	COG3237	CsbD-like
AC879_RS11030	COG2823	Periplasmic or secreted lipoprotein
AC879_RS11045	COG4181	ATPase activity
AC879_RS11055	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AC879_RS11060	COG0584	glycerophosphoryl diester phosphodiesterase
AC879_RS11065	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AC879_RS11075	COG0678	peroxiredoxin activity
AC879_RS11075	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AC879_RS11085	COG0789	Transcriptional regulator
AC879_RS11090	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AC879_RS11120	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AC879_RS11125	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AC879_RS11135	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AC879_RS11140	COG2252	PERMEase
AC879_RS11150	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AC879_RS11180	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AC879_RS11185	COG2358	TRAP transporter, solute receptor (TAXI family
AC879_RS11215	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AC879_RS11220	COG1366	Belongs to the anti-sigma-factor antagonist family
AC879_RS11225	COG2172	sigma factor antagonist activity
AC879_RS11230	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AC879_RS11240	COG2770	Histidine kinase
AC879_RS11240	COG2208	phosphoserine phosphatase activity
AC879_RS11265	COG1595	DNA-templated transcription, initiation
AC879_RS11280	COG4792	protein secretion
AC879_RS11285	COG4791	protein targeting
AC879_RS11290	COG4794	Type iii secretion
AC879_RS11295	COG4790	Type iii secretion
AC879_RS11330	COG4669	(LipO)protein
AC879_RS11395	COG4789	Type iii secretion
AC879_RS11425	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AC879_RS11430	COG0840	transmembrane signaling receptor activity
AC879_RS11435	COG2233	PERMEase
AC879_RS11460	COG0492	ferredoxin-NADP+ reductase activity
AC879_RS11465	COG1840	ABC-type Fe3 transport system, periplasmic component
AC879_RS11470	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AC879_RS11475	COG1178	ABC-type Fe3 transport system permease component
AC879_RS11480	COG3842	ATPase activity
AC879_RS11485	COG0583	DNA-binding transcription factor activity
AC879_RS11505	COG0501	Belongs to the peptidase M48B family
AC879_RS11515	COG0697	spore germination
AC879_RS11525	COG1846	Transcriptional regulator
AC879_RS11535	COG1566	PFAM secretion protein HlyD family protein
AC879_RS11540	COG2814	Major facilitator Superfamily
AC879_RS11545	COG0473	3-isopropylmalate dehydrogenase activity
AC879_RS11555	COG0747	negative chemotaxis
AC879_RS11565	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AC879_RS11580	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AC879_RS11605	COG1012	belongs to the aldehyde dehydrogenase family
AC879_RS11615	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AC879_RS11620	COG1115	amino acid carrier protein
AC879_RS11625	COG0433	COG0433 Predicted ATPase
AC879_RS11630	COG0217	transcriptional regulatory protein
AC879_RS11635	COG0151	Belongs to the GarS family
AC879_RS11640	COG0408	coproporphyrinogen oxidase activity
AC879_RS11645	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AC879_RS11650	COG0799	negative regulation of ribosome biogenesis
AC879_RS11655	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AC879_RS11660	COG0424	maF-like protein
AC879_RS11665	COG3468	outer membrane autotransporter barrel domain protein
AC879_RS11705	COG1530	ribonuclease E activity
AC879_RS11710	COG0077	Prephenate dehydratase
AC879_RS11725	COG1132	(ABC) transporter
AC879_RS11730	COG0859	PFAM glycosyl transferase family 9
AC879_RS11755	COG2194	sulfuric ester hydrolase activity
AC879_RS11760	COG0438	transferase activity, transferring glycosyl groups
AC879_RS11765	COG0463	Glycosyl transferase, family 2
AC879_RS11770	COG0726	polysaccharide deacetylase
AC879_RS11775	COG0438	transferase activity, transferring glycosyl groups
AC879_RS11790	COG1643	Atp-dependent helicase
AC879_RS11795	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AC879_RS11795	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AC879_RS11800	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AC879_RS11810	COG0704	Plays a role in the regulation of phosphate uptake
AC879_RS11815	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AC879_RS11820	COG1960	acyl-CoA dehydrogenase activity
AC879_RS11845	COG1177	transmembrane transport
AC879_RS11850	COG1176	ABC-type spermidine putrescine transport system, permease component I
AC879_RS11855	COG3842	ATPase activity
AC879_RS11860	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AC879_RS11875	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AC879_RS11880	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AC879_RS11890	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AC879_RS11890	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AC879_RS11910	COG0372	Belongs to the citrate synthase family
AC879_RS11915	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AC879_RS11920	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AC879_RS11925	COG1053	succinate dehydrogenase
AC879_RS11930	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AC879_RS11935	COG2009	succinate dehydrogenase
AC879_RS11940	COG2188	Transcriptional regulator
AC879_RS11945	COG0039	L-malate dehydrogenase activity
AC879_RS11975	COG1981	membrane
AC879_RS12000	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AC879_RS12010	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AC879_RS12040	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AC879_RS12045	COG0148	phosphopyruvate hydratase activity
AC879_RS12055	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AC879_RS12060	COG0504	CTP synthase activity
AC879_RS12085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AC879_RS12095	COG0747	negative chemotaxis
AC879_RS12100	COG4172	Belongs to the ABC transporter superfamily
AC879_RS12105	COG1446	asparaginase
AC879_RS12135	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AC879_RS12150	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AC879_RS12155	COG0697	spore germination
AC879_RS12160	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AC879_RS12170	COG3193	protein, possibly involved in utilization of glycolate and propanediol
AC879_RS12175	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AC879_RS12180	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AC879_RS12185	COG0791	NLP P60 protein
AC879_RS12200	COG0583	DNA-binding transcription factor activity
AC879_RS12215	COG0583	DNA-binding transcription factor activity
AC879_RS12230	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AC879_RS12245	COG0670	Belongs to the BI1 family
AC879_RS12250	COG3181	Tripartite tricarboxylate transporter family receptor
AC879_RS12260	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AC879_RS12270	COG1381	Involved in DNA repair and RecF pathway recombination
AC879_RS12275	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AC879_RS12280	COG0571	ribonuclease III activity
AC879_RS12285	COG0681	Belongs to the peptidase S26 family
AC879_RS12290	COG0481	GTPase activity
AC879_RS12295	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AC879_RS12320	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AC879_RS12325	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AC879_RS12340	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AC879_RS12345	COG0416	fatty acid biosynthetic process
AC879_RS12350	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AC879_RS12355	COG1399	metal-binding, possibly nucleic acid-binding protein
AC879_RS12360	COG0424	maF-like protein
AC879_RS12370	COG3023	N-Acetylmuramoyl-L-alanine amidase
AC879_RS12375	COG1289	transmembrane transporter activity
AC879_RS12385	COG3022	response to hydroperoxide
AC879_RS12395	COG1028	Short-chain dehydrogenase reductase Sdr
AC879_RS12410	COG3486	L-lysine 6-monooxygenase (NADPH) activity
AC879_RS12440	COG2814	Major facilitator Superfamily
AC879_RS12460	COG3706	GGDEF domain
AC879_RS12485	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AC879_RS12490	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AC879_RS12495	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AC879_RS12500	COG1674	ftsk spoiiie
AC879_RS12505	COG0492	ferredoxin-NADP+ reductase activity
AC879_RS12510	COG1193	negative regulation of DNA recombination
AC879_RS12525	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AC879_RS12540	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AC879_RS12545	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AC879_RS12550	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AC879_RS12560	COG0745	RESPONSE REGULATOR receiver
AC879_RS12605	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AC879_RS12625	COG0612	Peptidase, M16
AC879_RS12635	COG0443	Heat shock 70 kDa protein
AC879_RS12645	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AC879_RS12655	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AC879_RS12660	COG1420	regulation of RNA biosynthetic process
AC879_RS12665	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AC879_RS12670	COG0497	DNA recombination
AC879_RS12675	COG0735	belongs to the Fur family
AC879_RS12680	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AC879_RS12685	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AC879_RS12690	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AC879_RS12725	COG0446	pyridine nucleotide-disulphide oxidoreductase
AC879_RS12725	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AC879_RS12730	COG4311	Sarcosine oxidase, delta subunit
AC879_RS12735	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AC879_RS12745	COG0583	DNA-binding transcription factor activity
AC879_RS12755	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AC879_RS12785	COG4964	Belongs to the GSP D family
AC879_RS12845	COG0181	hydroxymethylbilane synthase activity
AC879_RS12850	COG0861	Integral membrane protein TerC family
AC879_RS12855	COG0861	Integral membrane protein TerC family
AC879_RS12860	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AC879_RS12865	COG0045	succinate-CoA ligase (ADP-forming) activity
AC879_RS12875	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AC879_RS12885	COG2137	regulation of response to DNA damage stimulus
AC879_RS12890	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AC879_RS12910	COG1250	3-hydroxyacyl-CoA dehydrogenase
AC879_RS12910	COG1024	Enoyl-CoA hydratase
AC879_RS12915	COG3842	ATPase activity
AC879_RS12930	COG1028	Short-chain dehydrogenase reductase Sdr
AC879_RS12950	COG0583	DNA-binding transcription factor activity
AC879_RS12955	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AC879_RS12965	COG2974	May be involved in recombination
AC879_RS12970	COG0540	Belongs to the ATCase OTCase family
AC879_RS13045	COG0776	regulation of translation
AC879_RS13050	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AC879_RS13050	COG0072	phenylalanine-tRNA ligase activity
AC879_RS13055	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AC879_RS13060	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AC879_RS13065	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AC879_RS13080	COG0756	dUTP diphosphatase activity
AC879_RS13090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AC879_RS13105	COG0500	methyltransferase
AC879_RS13120	COG0586	Pfam SNARE associated Golgi protein
AC879_RS13150	COG1609	Transcriptional regulator
AC879_RS13155	COG4172	Belongs to the ABC transporter superfamily
AC879_RS13160	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AC879_RS13165	COG0601	transmembrane transport
AC879_RS13170	COG0747	negative chemotaxis
AC879_RS13185	COG1280	lysine exporter protein (LysE YggA)
AC879_RS13200	COG2814	Major facilitator Superfamily
AC879_RS13230	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AC879_RS13250	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AC879_RS13290	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AC879_RS13295	COG1116	anion transmembrane transporter activity
AC879_RS13305	COG1228	amidohydrolase
AC879_RS13320	COG0477	Major facilitator Superfamily
AC879_RS13330	COG3550	peptidyl-serine autophosphorylation
AC879_RS13345	COG0519	Catalyzes the synthesis of GMP from XMP
AC879_RS13345	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AC879_RS13390	COG0420	3'-5' exonuclease activity
AC879_RS13395	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AC879_RS13425	COG0395	ABC-type sugar transport system, permease component
AC879_RS13435	COG3842	ATPase activity
AC879_RS13465	COG3181	Tripartite tricarboxylate transporter family receptor
AC879_RS13500	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AC879_RS13525	COG0602	queuosine metabolic process
AC879_RS13530	COG0720	synthase
AC879_RS13535	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AC879_RS13540	COG0235	Class ii aldolase
AC879_RS13565	COG3064	Membrane
AC879_RS13565	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
AC879_RS13565	COG3210	domain, Protein
AC879_RS13570	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AC879_RS13570	COG0047	phosphoribosylformylglycinamidine synthase activity
AC879_RS13575	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AC879_RS13580	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AC879_RS13580	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AC879_RS13585	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AC879_RS13605	COG3539	Fimbrial protein
AC879_RS13615	COG2050	protein possibly involved in aromatic compounds catabolism
AC879_RS13620	COG1024	Enoyl-CoA hydratase
AC879_RS13625	COG1012	belongs to the aldehyde dehydrogenase family
AC879_RS13635	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AC879_RS13640	COG2151	metal-sulfur cluster biosynthetic enzyme
AC879_RS13645	COG3396	Phenylacetate-CoA oxygenase
AC879_RS13650	COG3460	Phenylacetate-CoA oxygenase
AC879_RS13655	COG3396	Phenylacetate-CoA oxygenase
AC879_RS13660	COG3327	negative regulation of DNA-templated transcription, initiation
AC879_RS13670	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AC879_RS13675	COG0501	Belongs to the peptidase M48B family
AC879_RS13680	COG1162	GTPase activity
AC879_RS13685	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AC879_RS13690	COG0601	transmembrane transport
AC879_RS13695	COG0747	negative chemotaxis
AC879_RS13740	COG0668	transmembrane transport
AC879_RS13745	COG0165	Argininosuccinate lyase
AC879_RS13765	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AC879_RS13770	COG0303	'Molybdopterin
AC879_RS13775	COG0521	Mo-molybdopterin cofactor biosynthetic process
AC879_RS13790	COG0315	cyclic pyranopterin monophosphate synthase activity
AC879_RS13800	COG0412	Dienelactone hydrolase
AC879_RS13810	COG0678	peroxiredoxin activity
AC879_RS13820	COG0697	spore germination
AC879_RS13825	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AC879_RS13850	COG0789	Transcriptional regulator
AC879_RS13870	COG1028	Short-chain dehydrogenase reductase Sdr
AC879_RS13880	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AC879_RS13885	COG1845	cytochrome c oxidase, subunit III
AC879_RS13890	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AC879_RS13900	COG0477	Major facilitator Superfamily
AC879_RS13930	COG3468	outer membrane autotransporter barrel domain protein
AC879_RS13940	COG1309	transcriptional regulator
AC879_RS13945	COG2271	Major facilitator Superfamily
AC879_RS13980	COG0506	proline dehydrogenase activity
AC879_RS13980	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AC879_RS13980	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AC879_RS13990	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AC879_RS13990	COG3008	intermembrane lipid transfer
AC879_RS13995	COG2995	paraquat-inducible protein a
AC879_RS14000	COG0542	response to heat
AC879_RS14005	COG4953	penicillin-binding protein 1C
AC879_RS14015	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AC879_RS14020	COG1278	Cold shock
AC879_RS14030	COG0183	Belongs to the thiolase family
AC879_RS14035	COG0038	chloride channel
AC879_RS14040	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AC879_RS14045	COG1570	exodeoxyribonuclease VII activity
AC879_RS14055	COG0811	peptide transport
AC879_RS14060	COG0848	biopolymer transport protein
AC879_RS14065	COG1663	tetraacyldisaccharide 4'-kinase activity
AC879_RS14070	COG2835	tetraacyldisaccharide 4'-kinase activity
AC879_RS14075	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AC879_RS14080	COG0563	adenylate kinase activity
AC879_RS14090	COG0728	peptidoglycan biosynthetic process
AC879_RS14100	COG0268	Binds directly to 16S ribosomal RNA
AC879_RS14130	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AC879_RS14155	COG0436	Aminotransferase
AC879_RS14160	COG3737	Protein of unknown function (DUF498/DUF598)
AC879_RS14165	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AC879_RS14170	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AC879_RS14175	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AC879_RS14185	COG0305	Participates in initiation and elongation during chromosome replication
AC879_RS14195	COG0359	binds to the 23S rRNA
AC879_RS14200	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AC879_RS14205	COG2965	DNA replication, synthesis of RNA primer
AC879_RS14210	COG0360	Binds together with S18 to 16S ribosomal RNA
AC879_RS14215	COG1469	GTP cyclohydrolase I activity
AC879_RS14220	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AC879_RS14225	COG0142	geranyltranstransferase activity
AC879_RS14230	COG1722	exodeoxyribonuclease VII activity
AC879_RS14240	COG3181	Tripartite tricarboxylate transporter family receptor
AC879_RS14260	COG2239	Acts as a magnesium transporter
AC879_RS14270	COG2855	membrane
AC879_RS14280	COG1473	amidohydrolase
AC879_RS14285	COG0318	PFAM AMP-dependent synthetase and ligase
AC879_RS14310	COG1501	Belongs to the glycosyl hydrolase 31 family
AC879_RS14315	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AC879_RS14320	COG2011	ABC-type metal ion transport system permease component
AC879_RS14340	COG1454	alcohol dehydrogenase
AC879_RS14370	COG2186	Transcriptional regulator
AC879_RS14375	COG3181	Tripartite tricarboxylate transporter family receptor
AC879_RS14395	COG1175	transmembrane transport
AC879_RS14400	COG0395	ABC-type sugar transport system, permease component
AC879_RS14405	COG3842	ATPase activity
AC879_RS14410	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AC879_RS14420	COG1653	transport
AC879_RS14440	COG2818	Glycosylase
AC879_RS14445	COG2982	Protein involved in outer membrane biogenesis
AC879_RS14455	COG1309	transcriptional regulator
AC879_RS14460	COG1028	Short-chain dehydrogenase reductase Sdr
AC879_RS14520	COG0583	DNA-binding transcription factor activity
AC879_RS14525	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AC879_RS14530	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AC879_RS14545	COG1028	Short-chain dehydrogenase reductase Sdr
AC879_RS14550	COG0477	Major facilitator Superfamily
AC879_RS14560	COG0583	DNA-binding transcription factor activity
AC879_RS14565	COG1448	Aminotransferase
AC879_RS14570	COG1418	mRNA catabolic process
AC879_RS14595	COG1063	alcohol dehydrogenase
AC879_RS14615	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AC879_RS14625	COG0318	PFAM AMP-dependent synthetase and ligase
AC879_RS14635	COG1522	sequence-specific DNA binding
AC879_RS14640	COG3181	Tripartite tricarboxylate transporter family receptor
AC879_RS14645	COG0307	riboflavin synthase, alpha
AC879_RS14650	COG0154	amidase activity
AC879_RS14670	COG2807	transmembrane transport
AC879_RS14675	COG0590	tRNA wobble adenosine to inosine editing
AC879_RS14685	COG0583	DNA-binding transcription factor activity
AC879_RS14700	COG1902	pentaerythritol trinitrate reductase activity
AC879_RS14720	COG0559	Belongs to the binding-protein-dependent transport system permease family
AC879_RS14725	COG0251	oxidation-reduction process
AC879_RS14730	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AC879_RS14740	COG1414	Transcriptional regulator
AC879_RS14745	COG1028	Short-chain dehydrogenase reductase Sdr
AC879_RS14760	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AC879_RS14775	COG1024	Enoyl-CoA hydratase
AC879_RS14780	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AC879_RS14785	COG0154	amidase activity
AC879_RS14825	COG3909	cytochrome
AC879_RS14830	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AC879_RS14835	COG0625	glutathione transferase activity
AC879_RS14840	COG0730	response to heat
AC879_RS14845	COG0482	sulfurtransferase activity
AC879_RS14850	COG0583	DNA-binding transcription factor activity
AC879_RS14870	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AC879_RS14895	COG2819	hydrolase of the alpha beta superfamily
AC879_RS14900	COG0247	lactate metabolic process
AC879_RS14905	COG0277	FAD linked oxidase domain protein
AC879_RS14910	COG0277	FAD linked oxidase domain protein
AC879_RS14915	COG0277	FAD linked oxidase domain protein
AC879_RS14920	COG3210	domain, Protein
AC879_RS14920	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
AC879_RS14920	COG3064	Membrane
AC879_RS14920	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
AC879_RS14920	COG3210	domain, Protein
AC879_RS14920	COG3064	Membrane
AC879_RS14925	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AC879_RS14930	COG0312	modulator of DNA gyrase
AC879_RS14965	COG1666	GTP binding
AC879_RS15010	COG3220	belongs to the UPF0276 family
AC879_RS15030	COG0640	Transcriptional regulator
AC879_RS15035	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AC879_RS15040	COG1845	cytochrome c oxidase, subunit III
AC879_RS15045	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AC879_RS15055	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
AC879_RS15090	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AC879_RS15095	COG0583	DNA-binding transcription factor activity
AC879_RS15125	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AC879_RS15125	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AC879_RS15140	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AC879_RS15145	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AC879_RS15155	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AC879_RS15170	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AC879_RS15175	COG0316	Belongs to the HesB IscA family
AC879_RS15185	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AC879_RS15190	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AC879_RS15195	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AC879_RS15200	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AC879_RS15205	COG0312	modulator of DNA gyrase
AC879_RS15210	COG3028	Belongs to the UPF0307 family
AC879_RS15225	COG1116	anion transmembrane transporter activity
AC879_RS15230	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AC879_RS15235	COG1335	isochorismatase
AC879_RS15240	COG0346	lactoylglutathione lyase activity
AC879_RS15245	COG0513	Belongs to the DEAD box helicase family
AC879_RS15250	COG3069	C4-dicarboxylate transmembrane transporter activity
AC879_RS15255	COG1802	Transcriptional regulator
AC879_RS15270	COG1042	CoA-binding domain protein
AC879_RS15270	COG0045	succinate-CoA ligase (ADP-forming) activity
AC879_RS15270	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AC879_RS15275	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AC879_RS15290	COG1522	sequence-specific DNA binding
AC879_RS15325	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AC879_RS15330	COG1696	Membrane protein involved in D-alanine export
AC879_RS15355	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AC879_RS15365	COG2264	protein methyltransferase activity
AC879_RS15370	COG0439	Biotin carboxylase
AC879_RS15375	COG0511	ligase activity, forming carbon-carbon bonds
AC879_RS15380	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AC879_RS15385	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AC879_RS15390	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AC879_RS15395	COG3150	esterase
AC879_RS15400	COG0557	exoribonuclease II activity
AC879_RS15410	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AC879_RS15430	COG1522	sequence-specific DNA binding
AC879_RS15435	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AC879_RS15440	COG1028	Short-chain dehydrogenase reductase Sdr
AC879_RS15460	COG0653	protein targeting
AC879_RS15465	COG0739	heme binding
AC879_RS15475	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AC879_RS15480	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AC879_RS15490	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AC879_RS15495	COG1181	Belongs to the D-alanine--D-alanine ligase family
AC879_RS15500	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AC879_RS15505	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AC879_RS15515	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AC879_RS15520	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AC879_RS15525	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AC879_RS15535	COG3116	cell division
AC879_RS15540	COG0275	rRNA processing
AC879_RS15545	COG2001	Belongs to the MraZ family
AC879_RS15555	COG0488	(ABC) transporter
AC879_RS15560	COG0418	dihydroorotase activity
AC879_RS15565	COG1473	amidohydrolase
AC879_RS15615	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AC879_RS15620	COG4654	Cytochrome c, class I
AC879_RS15625	COG0129	dihydroxy-acid dehydratase activity
AC879_RS15630	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AC879_RS15680	COG2084	Dehydrogenase
AC879_RS15685	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AC879_RS15695	COG2096	Adenosyltransferase
AC879_RS15705	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AC879_RS15710	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AC879_RS15720	COG0523	cobalamin synthesis protein
AC879_RS15725	COG0735	belongs to the Fur family
AC879_RS15745	COG0803	Belongs to the bacterial solute-binding protein 9 family
AC879_RS15755	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
AC879_RS15765	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AC879_RS15775	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AC879_RS15780	COG1560	Kdo2-lipid A biosynthetic process
AC879_RS15790	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AC879_RS15805	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AC879_RS15810	COG1950	PFAM Membrane protein of
AC879_RS15825	COG0583	DNA-binding transcription factor activity
AC879_RS15835	COG0477	Major facilitator Superfamily
AC879_RS15850	COG0617	tRNA 3'-terminal CCA addition
AC879_RS15860	COG0513	Belongs to the DEAD box helicase family
AC879_RS15865	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AC879_RS15880	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AC879_RS15885	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AC879_RS15945	COG1280	lysine exporter protein (LysE YggA)
AC879_RS15960	COG0405	Gamma-glutamyltransferase
AC879_RS15970	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AC879_RS16000	COG1309	transcriptional regulator
AC879_RS16010	COG3181	Tripartite tricarboxylate transporter family receptor
AC879_RS16020	COG0745	RESPONSE REGULATOR receiver
AC879_RS16085	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AC879_RS16110	COG0582	viral genome integration into host DNA
AC879_RS16115	COG0012	GTP binding
AC879_RS16125	COG0193	aminoacyl-tRNA hydrolase activity
AC879_RS16130	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AC879_RS16135	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AC879_RS16145	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AC879_RS16150	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AC879_RS16160	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AC879_RS16185	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AC879_RS16195	COG1368	sulfuric ester hydrolase activity
AC879_RS16200	COG0642	Histidine kinase
AC879_RS16205	COG0745	RESPONSE REGULATOR receiver
AC879_RS16210	COG0277	FAD linked oxidase domain protein
AC879_RS16225	COG0166	Belongs to the GPI family
AC879_RS16230	COG0438	transferase activity, transferring glycosyl groups
AC879_RS16235	COG0438	transferase activity, transferring glycosyl groups
AC879_RS16250	COG0438	transferase activity, transferring glycosyl groups
AC879_RS16265	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AC879_RS16270	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AC879_RS16275	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
AC879_RS16285	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AC879_RS16295	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AC879_RS16300	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AC879_RS16310	COG0747	negative chemotaxis
AC879_RS16315	COG0601	transmembrane transport
AC879_RS16320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AC879_RS16340	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AC879_RS16345	COG0830	nickel cation binding
AC879_RS16355	COG0804	urea catabolic process
AC879_RS16360	COG0832	Belongs to the urease beta subunit family
AC879_RS16370	COG0831	urea catabolic process
AC879_RS16375	COG0829	nickel cation binding
AC879_RS16385	COG0633	Ferredoxin
AC879_RS16400	COG2188	Transcriptional regulator
AC879_RS16425	COG2719	SpoVR family
AC879_RS16430	COG2718	Belongs to the UPF0229 family
AC879_RS16445	COG1028	Short-chain dehydrogenase reductase Sdr
AC879_RS16450	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AC879_RS16465	COG1960	acyl-CoA dehydrogenase activity
AC879_RS16510	COG0183	Belongs to the thiolase family
AC879_RS16515	COG2030	dehydratase
AC879_RS16570	COG0328	RNA-DNA hybrid ribonuclease activity
AC879_RS16575	COG2226	methyltransferase
AC879_RS16580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AC879_RS16585	COG1388	LysM domain
AC879_RS16585	COG0741	lytic transglycosylase activity
AC879_RS16605	COG2979	Protein of unknown function (DUF533)
AC879_RS16640	COG1271	oxidase subunit
AC879_RS16645	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AC879_RS16650	COG0850	regulation of cytokinetic process
AC879_RS16655	COG2894	cell division
AC879_RS16660	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AC879_RS16680	COG0488	(ABC) transporter
AC879_RS16695	COG0601	transmembrane transport
AC879_RS16705	COG1215	transferase activity, transferring glycosyl groups
AC879_RS16720	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AC879_RS16730	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AC879_RS16750	COG0318	PFAM AMP-dependent synthetase and ligase
AC879_RS16755	COG2188	Transcriptional regulator
AC879_RS16760	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AC879_RS16765	COG2814	Major facilitator Superfamily
AC879_RS16775	COG0259	pyridoxamine-phosphate oxidase activity
AC879_RS16780	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AC879_RS16795	COG0583	DNA-binding transcription factor activity
AC879_RS16800	COG1960	acyl-CoA dehydrogenase activity
AC879_RS16820	COG0134	indole-3-glycerol-phosphate synthase activity
AC879_RS16825	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AC879_RS16830	COG0512	Glutamine amidotransferase of anthranilate synthase
AC879_RS16840	COG0546	phosphoglycolate phosphatase activity
AC879_RS16845	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AC879_RS16850	COG2967	ApaG domain
AC879_RS16855	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AC879_RS16860	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AC879_RS16865	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AC879_RS16870	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AC879_RS16880	COG0037	tRNA processing
AC879_RS16890	COG3634	alkyl hydroperoxide reductase activity
AC879_RS16895	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AC879_RS16900	COG1024	Enoyl-CoA hydratase
AC879_RS16925	COG0356	it plays a direct role in the translocation of protons across the membrane
AC879_RS16935	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AC879_RS16940	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AC879_RS16945	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AC879_RS16950	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AC879_RS16955	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AC879_RS16960	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AC879_RS16970	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AC879_RS16975	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AC879_RS16980	COG0210	DNA helicase
AC879_RS16990	COG2195	Cleaves the N-terminal amino acid of tripeptides
AC879_RS17000	COG4172	Belongs to the ABC transporter superfamily
AC879_RS17005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AC879_RS17010	COG0601	transmembrane transport
AC879_RS17030	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AC879_RS17035	COG1024	Enoyl-CoA hydratase
AC879_RS17040	COG1024	Enoyl-CoA hydratase
AC879_RS17065	COG1250	3-hydroxyacyl-CoA dehydrogenase
AC879_RS17095	COG2132	Multicopper oxidase
AC879_RS17105	COG1024	Enoyl-CoA hydratase
AC879_RS17105	COG1250	3-hydroxyacyl-CoA dehydrogenase
AC879_RS17115	COG1414	Transcriptional regulator
AC879_RS17125	COG0154	amidase activity
AC879_RS17155	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AC879_RS17160	COG3568	Endonuclease Exonuclease Phosphatase
AC879_RS17165	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AC879_RS17200	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AC879_RS17210	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AC879_RS17225	COG1137	ATPase activity
AC879_RS17230	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AC879_RS17240	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AC879_RS17245	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AC879_RS17245	COG2010	Cytochrome c
AC879_RS17255	COG1660	Displays ATPase and GTPase activities
AC879_RS17260	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AC879_RS17295	COG3181	Tripartite tricarboxylate transporter family receptor
AC879_RS17305	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AC879_RS17310	COG2890	protein-(glutamine-N5) methyltransferase activity
AC879_RS17315	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AC879_RS17320	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AC879_RS17370	COG1960	acyl-CoA dehydrogenase activity
AC879_RS17380	COG0183	Belongs to the thiolase family
AC879_RS17385	COG1522	sequence-specific DNA binding
AC879_RS17390	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AC879_RS17410	COG1024	Enoyl-CoA hydratase
AC879_RS17425	COG0604	alcohol dehydrogenase
AC879_RS17445	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AC879_RS17455	COG1960	acyl-CoA dehydrogenase activity
AC879_RS17460	COG1960	acyl-CoA dehydrogenase activity
AC879_RS17465	COG0277	FAD linked oxidase domain protein
AC879_RS17475	COG3181	Tripartite tricarboxylate transporter family receptor
AC879_RS17500	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AC879_RS17510	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AC879_RS17515	COG3181	Tripartite tricarboxylate transporter family receptor
AC879_RS17520	COG1960	acyl-CoA dehydrogenase activity
AC879_RS17540	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AC879_RS17545	COG1024	Enoyl-CoA hydratase
AC879_RS17550	COG1960	acyl-CoA dehydrogenase activity
AC879_RS17570	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AC879_RS17575	COG0022	dehydrogenase e1 component
AC879_RS17580	COG1024	Enoyl-CoA hydratase
AC879_RS17585	COG0508	dehydrogenase complex catalyzes the overall conversion of
AC879_RS17605	COG0683	leucine binding
AC879_RS17610	COG0559	Belongs to the binding-protein-dependent transport system permease family
AC879_RS17615	COG0411	ABC transporter
AC879_RS17625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AC879_RS17640	COG3181	Tripartite tricarboxylate transporter family receptor
AC879_RS17665	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AC879_RS17670	COG0793	Belongs to the peptidase S41A family
AC879_RS17675	COG4942	peptidase
AC879_RS17680	COG0588	phosphoglycerate mutase activity
AC879_RS17685	COG1054	Belongs to the UPF0176 family
AC879_RS17690	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AC879_RS17695	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AC879_RS17700	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AC879_RS17705	COG3181	Tripartite tricarboxylate transporter family receptor
AC879_RS17720	COG2226	methyltransferase
AC879_RS17725	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AC879_RS17740	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AC879_RS17745	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AC879_RS17770	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AC879_RS17795	COG1335	isochorismatase
AC879_RS17800	COG2309	aminopeptidase activity
AC879_RS17805	COG0596	Alpha beta hydrolase
AC879_RS17810	COG3473	Maleate cis-trans isomerase
AC879_RS17820	COG2068	MobA-Related Protein
AC879_RS17845	COG2204	response regulator
AC879_RS17850	COG5000	phosphorelay sensor kinase activity
AC879_RS17860	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AC879_RS17860	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AC879_RS17870	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
AC879_RS17900	COG0583	DNA-binding transcription factor activity
AC879_RS17915	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AC879_RS17920	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AC879_RS17925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AC879_RS17940	COG0758	DNA mediated transformation
AC879_RS17945	COG1522	sequence-specific DNA binding
AC879_RS17955	COG0242	peptide deformylase activity
AC879_RS17970	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AC879_RS17980	COG0546	phosphoglycolate phosphatase activity
AC879_RS18000	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AC879_RS18005	COG1942	4-Oxalocrotonate Tautomerase
AC879_RS18010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AC879_RS18035	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AC879_RS18055	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AC879_RS18060	COG1024	Enoyl-CoA hydratase
AC879_RS18065	COG1414	Transcriptional regulator
AC879_RS18070	COG0318	PFAM AMP-dependent synthetase and ligase
AC879_RS18075	COG3181	Tripartite tricarboxylate transporter family receptor
AC879_RS18105	COG0583	DNA-binding transcription factor activity
AC879_RS18120	COG3422	double-strand break repair
AC879_RS18125	COG0330	HflC and HflK could
AC879_RS18135	COG0251	oxidation-reduction process
AC879_RS18180	COG3723	Recombinational DNA repair protein, rece pathway
AC879_RS18215	COG0582	viral genome integration into host DNA
AC879_RS18240	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AC879_RS18250	COG0706	membrane insertase activity
AC879_RS18255	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AC879_RS18260	COG0594	ribonuclease P activity
AC879_RS18265	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AC879_RS18270	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AC879_RS18285	COG1414	Transcriptional regulator
AC879_RS18290	COG0154	amidase activity
AC879_RS18305	COG1304	FMN binding
AC879_RS18325	COG1960	acyl-CoA dehydrogenase activity
AC879_RS18345	COG1960	acyl-CoA dehydrogenase activity
AC879_RS18360	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AC879_RS18375	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AC879_RS18380	COG3181	Tripartite tricarboxylate transporter family receptor
AC879_RS18390	COG2358	TRAP transporter, solute receptor (TAXI family
AC879_RS18400	COG1629	transport
AC879_RS18405	COG2922	Belongs to the Smg family
AC879_RS18430	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AC879_RS18435	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AC879_RS18440	COG1028	Short-chain dehydrogenase reductase Sdr
AC879_RS18445	COG1012	belongs to the aldehyde dehydrogenase family
AC879_RS18455	COG0028	Belongs to the TPP enzyme family
AC879_RS18460	COG1522	sequence-specific DNA binding
AC879_RS18465	COG3781	membrane
AC879_RS18475	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AC879_RS18500	COG4206	TonB-dependent receptor
AC879_RS18505	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AC879_RS18510	COG2022	thiamine diphosphate biosynthetic process
AC879_RS18515	COG0351	phosphomethylpyrimidine kinase
AC879_RS18520	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AC879_RS18535	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AC879_RS18545	COG0628	permease
AC879_RS18555	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AC879_RS18565	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AC879_RS18570	COG0049	tRNA binding
AC879_RS18575	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AC879_RS18580	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AC879_RS18585	COG0051	transcription antitermination factor activity, RNA binding
AC879_RS18590	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AC879_RS18595	COG0088	Forms part of the polypeptide exit tunnel
AC879_RS18600	COG0089	rRNA binding
AC879_RS18605	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AC879_RS18610	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AC879_RS18615	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AC879_RS18620	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AC879_RS18625	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AC879_RS18630	COG0255	Belongs to the universal ribosomal protein uL29 family
AC879_RS18635	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AC879_RS18655	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AC879_RS18660	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AC879_RS18665	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AC879_RS18670	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AC879_RS18675	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AC879_RS18680	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AC879_RS18685	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AC879_RS18690	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AC879_RS18695	COG1841	ribosomal large subunit assembly
AC879_RS18700	COG0200	Binds to the 23S rRNA
AC879_RS18705	COG0201	protein transport
AC879_RS18710	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AC879_RS18715	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AC879_RS18720	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AC879_RS18725	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AC879_RS18730	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AC879_RS18735	COG0202	RNA polymerase activity
AC879_RS18740	COG0203	ribosomal protein L17
AC879_RS18745	COG0537	adenosine 5'-monophosphoramidase activity
AC879_RS18750	COG1324	tolerance protein
AC879_RS18755	COG4232	protein-disulfide reductase activity
AC879_RS18770	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AC879_RS18780	COG1333	cytochrome c biogenesis protein
AC879_RS18785	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AC879_RS18800	COG1965	Belongs to the frataxin family
AC879_RS18810	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AC879_RS18815	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AC879_RS18820	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AC879_RS18835	COG2814	Major facilitator Superfamily
AC879_RS18840	COG0629	single-stranded DNA binding
AC879_RS18880	COG0402	S-adenosylhomocysteine deaminase activity
AC879_RS18890	COG0438	transferase activity, transferring glycosyl groups
AC879_RS18910	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AC879_RS18935	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AC879_RS18940	COG2186	Transcriptional regulator
AC879_RS18960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AC879_RS18965	COG1956	GAF domain-containing protein
AC879_RS18970	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AC879_RS18985	COG1652	LysM domain
AC879_RS19000	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AC879_RS19015	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AC879_RS19045	COG3181	Tripartite tricarboxylate transporter family receptor
AC879_RS19060	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AC879_RS19075	COG1024	Enoyl-CoA hydratase
AC879_RS19090	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AC879_RS19095	COG1309	transcriptional regulator
AC879_RS19100	COG2816	NAD+ diphosphatase activity
AC879_RS19105	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AC879_RS19190	COG2814	Major facilitator Superfamily
AC879_RS19195	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AC879_RS19215	COG1999	signal sequence binding
AC879_RS19220	COG0109	protoheme IX farnesyltransferase activity
AC879_RS19260	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AC879_RS19280	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AC879_RS19285	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AC879_RS19295	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AC879_RS19300	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AC879_RS19310	COG0069	glutamate synthase activity
AC879_RS19310	COG0070	glutamate synthase
AC879_RS19310	COG0067	glutamate synthase
AC879_RS19320	COG3047	cAMP biosynthetic process
AC879_RS19330	COG1127	ABC transporter
AC879_RS19335	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AC879_RS19340	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AC879_RS19345	COG2853	Lipoprotein
AC879_RS19355	COG1131	(ABC) transporter
AC879_RS19360	COG0842	Transport permease protein
AC879_RS19370	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AC879_RS19375	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AC879_RS19380	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AC879_RS19385	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AC879_RS19390	COG0131	Imidazoleglycerol-phosphate dehydratase
AC879_RS19395	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AC879_RS19400	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AC879_RS19405	COG0107	imidazoleglycerol-phosphate synthase activity
AC879_RS19410	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AC879_RS19415	COG0140	phosphoribosyl-ATP diphosphatase activity
AC879_RS19420	COG0537	adenosine 5'-monophosphoramidase activity
AC879_RS19425	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AC879_RS19430	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AC879_RS19445	COG3181	Tripartite tricarboxylate transporter family receptor
AC879_RS19480	COG3702	type iv secretory pathway
AC879_RS19485	COG3451	type IV secretory pathway VirB4
AC879_RS19500	COG3736	Type IV secretory pathway, component VirB8
AC879_RS19505	COG3504	Conjugal transfer protein
AC879_RS19510	COG2948	multi-organism process
AC879_RS19515	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
AC879_RS19525	COG0697	spore germination
AC879_RS19545	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AC879_RS19550	COG0747	negative chemotaxis
AC879_RS19555	COG0601	transmembrane transport
AC879_RS19560	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AC879_RS19565	COG0444	Belongs to the ABC transporter superfamily
AC879_RS19575	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AC879_RS19585	COG0494	nUDIX hydrolase
AC879_RS19620	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
AC879_RS19625	COG0237	dephospho-CoA kinase activity
AC879_RS19630	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AC879_RS19645	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AC879_RS19650	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AC879_RS19660	COG0477	Major facilitator Superfamily
AC879_RS19665	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AC879_RS19680	COG1126	abc transporter atp-binding protein
AC879_RS19685	COG0765	amino acid transport
AC879_RS19690	COG4597	amino acid ABC transporter
AC879_RS19695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AC879_RS19700	COG2884	Cell division ATP-binding protein ftsE
AC879_RS19705	COG2177	Part of the ABC transporter FtsEX involved in
AC879_RS19710	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AC879_RS19720	COG1194	a g-specific adenine glycosylase
AC879_RS19730	COG2226	methyltransferase
AC879_RS19740	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AC879_RS19745	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AC879_RS19760	COG1024	Enoyl-CoA hydratase
AC879_RS19780	COG1024	Enoyl-CoA hydratase
AC879_RS19785	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AC879_RS19790	COG3181	Tripartite tricarboxylate transporter family receptor
AC879_RS19800	COG0753	catalase activity
AC879_RS19805	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AC879_RS19810	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AC879_RS19820	COG2175	clavaminate synthase activity
AC879_RS19825	COG1473	amidohydrolase
AC879_RS19830	COG4608	Belongs to the ABC transporter superfamily
AC879_RS19835	COG0444	Belongs to the ABC transporter superfamily
AC879_RS19850	COG0747	negative chemotaxis
AC879_RS19855	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AC879_RS19890	COG0436	Aminotransferase
AC879_RS19895	COG1278	Cold shock