locus-tag	class	description
ABC16_RS00005	COG0445	tRNA wobble uridine modification
ABC16_RS00010	COG0357	Ribosomal RNA small subunit methyltransferase G
ABC16_RS00015	COG1192	Involved in chromosome partitioning
ABC16_RS00025	COG1475	DNA binding
ABC16_RS00030	COG0252	asparaginase activity
ABC16_RS00055	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ABC16_RS00065	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ABC16_RS00075	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ABC16_RS00080	COG0081	regulation of translation
ABC16_RS00085	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ABC16_RS00090	COG0222	ribosome binding
ABC16_RS00095	COG0085	RNA polymerase activity
ABC16_RS00100	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ABC16_RS00140	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC16_RS00165	COG1024	Enoyl-CoA hydratase
ABC16_RS00185	COG0752	glycyl-tRNA synthetase alpha subunit
ABC16_RS00190	COG0751	glycine-tRNA ligase activity
ABC16_RS00195	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ABC16_RS00200	COG0204	Acyl-transferase
ABC16_RS00215	COG0242	peptide deformylase activity
ABC16_RS00250	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ABC16_RS00255	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ABC16_RS00260	COG2813	Specifically methylates the guanine in position
ABC16_RS00260	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ABC16_RS00275	COG2223	nitrite transmembrane transporter activity
ABC16_RS00285	COG1794	racemase activity, acting on amino acids and derivatives
ABC16_RS00290	COG1126	abc transporter atp-binding protein
ABC16_RS00295	COG0765	amino acid transport
ABC16_RS00300	COG0765	amino acid transport
ABC16_RS00305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABC16_RS00370	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ABC16_RS00400	COG0326	Molecular chaperone. Has ATPase activity
ABC16_RS00405	COG0625	glutathione transferase activity
ABC16_RS00420	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ABC16_RS00425	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ABC16_RS00455	COG0438	transferase activity, transferring glycosyl groups
ABC16_RS00460	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ABC16_RS00465	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ABC16_RS00495	COG0859	PFAM glycosyl transferase family 9
ABC16_RS00510	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ABC16_RS00520	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ABC16_RS00525	COG1127	ABC transporter
ABC16_RS00545	COG1686	Belongs to the peptidase S11 family
ABC16_RS00555	COG2921	Belongs to the UPF0250 family
ABC16_RS00560	COG0321	lipoyl(octanoyl) transferase activity
ABC16_RS00565	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ABC16_RS00600	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ABC16_RS00610	COG0018	arginyl-trna synthetase
ABC16_RS00630	COG0395	ABC-type sugar transport system, permease component
ABC16_RS00635	COG1175	transmembrane transport
ABC16_RS00640	COG1653	transport
ABC16_RS00645	COG3842	ATPase activity
ABC16_RS00650	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ABC16_RS00660	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ABC16_RS00680	COG1609	Transcriptional regulator
ABC16_RS00690	COG0154	amidase activity
ABC16_RS00695	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ABC16_RS00705	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ABC16_RS00715	COG0583	DNA-binding transcription factor activity
ABC16_RS00730	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ABC16_RS00735	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ABC16_RS00750	COG1802	Transcriptional regulator
ABC16_RS00765	COG1024	Enoyl-CoA hydratase
ABC16_RS00775	COG3181	Tripartite tricarboxylate transporter family receptor
ABC16_RS00790	COG1984	allophanate hydrolase subunit 2
ABC16_RS00795	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ABC16_RS00805	COG0583	DNA-binding transcription factor activity
ABC16_RS00810	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ABC16_RS00820	COG5002	protein histidine kinase activity
ABC16_RS00830	COG5002	protein histidine kinase activity
ABC16_RS00835	COG0745	RESPONSE REGULATOR receiver
ABC16_RS00840	COG2226	methyltransferase
ABC16_RS00855	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ABC16_RS00875	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
ABC16_RS00885	COG0513	Belongs to the DEAD box helicase family
ABC16_RS00890	COG1280	lysine exporter protein (LysE YggA)
ABC16_RS00895	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ABC16_RS00930	COG1054	Belongs to the UPF0176 family
ABC16_RS00935	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ABC16_RS00935	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ABC16_RS00945	COG0489	protein tyrosine kinase activity
ABC16_RS00960	COG0717	Belongs to the dCTP deaminase family
ABC16_RS00990	COG2081	HI0933 family
ABC16_RS01000	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ABC16_RS01010	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ABC16_RS01015	COG0509	glycine decarboxylation via glycine cleavage system
ABC16_RS01020	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ABC16_RS01020	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ABC16_RS01060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ABC16_RS01075	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ABC16_RS01085	COG1414	Transcriptional regulator
ABC16_RS01090	COG1028	Short-chain dehydrogenase reductase Sdr
ABC16_RS01095	COG2031	fatty acid transporter
ABC16_RS01100	COG1250	3-hydroxyacyl-CoA dehydrogenase
ABC16_RS01110	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ABC16_RS01115	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ABC16_RS01125	COG4257	antibiotic catabolic process
ABC16_RS01150	COG1012	belongs to the aldehyde dehydrogenase family
ABC16_RS01155	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ABC16_RS01160	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ABC16_RS01190	COG1028	Short-chain dehydrogenase reductase Sdr
ABC16_RS01200	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ABC16_RS01215	COG2188	Transcriptional regulator
ABC16_RS01220	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ABC16_RS01245	COG0617	tRNA 3'-terminal CCA addition
ABC16_RS01260	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ABC16_RS01265	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ABC16_RS01270	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ABC16_RS01275	COG0586	Pfam SNARE associated Golgi protein
ABC16_RS01280	COG0860	N-Acetylmuramoyl-L-alanine amidase
ABC16_RS01285	COG0802	atpase or kinase
ABC16_RS01290	COG0114	fumarate hydratase activity
ABC16_RS01300	COG3181	Tripartite tricarboxylate transporter family receptor
ABC16_RS01310	COG0405	Gamma-glutamyltransferase
ABC16_RS01315	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC16_RS01325	COG1960	acyl-CoA dehydrogenase activity
ABC16_RS01345	COG1294	oxidase, subunit
ABC16_RS01355	COG4988	ABC transporter
ABC16_RS01360	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ABC16_RS01365	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ABC16_RS01380	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ABC16_RS01410	COG2969	positive regulation of protein catabolic process
ABC16_RS01415	COG0625	glutathione transferase activity
ABC16_RS01420	COG2857	Cytochrome c1
ABC16_RS01425	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ABC16_RS01430	COG0723	plastoquinol--plastocyanin reductase activity
ABC16_RS01435	COG1970	mechanosensitive ion channel activity
ABC16_RS01440	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ABC16_RS01455	COG2808	Putative FMN-binding domain
ABC16_RS01460	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ABC16_RS01465	COG0747	negative chemotaxis
ABC16_RS01470	COG0657	acetylesterase activity
ABC16_RS01480	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ABC16_RS01485	COG2207	Transcriptional regulator
ABC16_RS01490	COG0129	dihydroxy-acid dehydratase activity
ABC16_RS01495	COG2814	Major facilitator Superfamily
ABC16_RS01500	COG0583	DNA-binding transcription factor activity
ABC16_RS01510	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
ABC16_RS01580	COG1024	Enoyl-CoA hydratase
ABC16_RS01585	COG1960	acyl-CoA dehydrogenase activity
ABC16_RS01610	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ABC16_RS01615	COG0352	thiamine-phosphate diphosphorylase activity
ABC16_RS01630	COG1678	Uncharacterized ACR, COG1678
ABC16_RS01635	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ABC16_RS01640	COG0540	Belongs to the ATCase OTCase family
ABC16_RS01655	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ABC16_RS01665	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ABC16_RS01700	COG1234	tRNA 3'-trailer cleavage
ABC16_RS01720	COG3064	Membrane
ABC16_RS01750	COG1683	Conserved Protein
ABC16_RS01755	COG1120	ATPase activity
ABC16_RS01760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ABC16_RS01765	COG4558	Periplasmic binding protein
ABC16_RS01770	COG3720	iron ion transport
ABC16_RS01780	COG3712	iron ion homeostasis
ABC16_RS01785	COG1595	DNA-templated transcription, initiation
ABC16_RS01820	COG1802	Transcriptional regulator
ABC16_RS01830	COG3069	C4-dicarboxylate transmembrane transporter activity
ABC16_RS01840	COG1012	belongs to the aldehyde dehydrogenase family
ABC16_RS01875	COG2860	membrane
ABC16_RS01880	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ABC16_RS01885	COG0708	Exodeoxyribonuclease III
ABC16_RS01890	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ABC16_RS01895	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ABC16_RS01900	COG0154	amidase activity
ABC16_RS01905	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ABC16_RS01910	COG1077	Cell shape determining protein MreB Mrl
ABC16_RS01915	COG1792	Involved in formation and maintenance of cell shape
ABC16_RS01925	COG0768	penicillin binding
ABC16_RS01930	COG0772	Belongs to the SEDS family
ABC16_RS01935	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ABC16_RS01940	COG0471	metal ion transport
ABC16_RS01945	COG1309	transcriptional regulator
ABC16_RS01955	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ABC16_RS01970	COG2823	Periplasmic or secreted lipoprotein
ABC16_RS01975	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ABC16_RS01990	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ABC16_RS02010	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC16_RS02020	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC16_RS02040	COG0492	ferredoxin-NADP+ reductase activity
ABC16_RS02050	COG3181	Tripartite tricarboxylate transporter family receptor
ABC16_RS02055	COG1024	Enoyl-CoA hydratase
ABC16_RS02055	COG1250	3-hydroxyacyl-CoA dehydrogenase
ABC16_RS02060	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC16_RS02065	COG0028	Belongs to the TPP enzyme family
ABC16_RS02090	COG3181	Tripartite tricarboxylate transporter family receptor
ABC16_RS02100	COG0697	spore germination
ABC16_RS02130	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ABC16_RS02135	COG0463	Glycosyl transferase, family 2
ABC16_RS02155	COG0786	glutamate:sodium symporter activity
ABC16_RS02165	COG2031	fatty acid transporter
ABC16_RS02180	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ABC16_RS02185	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ABC16_RS02210	COG3181	Tripartite tricarboxylate transporter family receptor
ABC16_RS02220	COG0277	FAD linked oxidase domain protein
ABC16_RS02225	COG1960	acyl-CoA dehydrogenase activity
ABC16_RS02230	COG1960	acyl-CoA dehydrogenase activity
ABC16_RS02240	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ABC16_RS02255	COG2072	flavoprotein involved in K transport
ABC16_RS02260	COG0604	alcohol dehydrogenase
ABC16_RS02275	COG1024	Enoyl-CoA hydratase
ABC16_RS02295	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ABC16_RS02300	COG1522	sequence-specific DNA binding
ABC16_RS02305	COG0183	Belongs to the thiolase family
ABC16_RS02315	COG1960	acyl-CoA dehydrogenase activity
ABC16_RS02360	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ABC16_RS02365	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ABC16_RS02370	COG2890	protein-(glutamine-N5) methyltransferase activity
ABC16_RS02375	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ABC16_RS02385	COG3181	Tripartite tricarboxylate transporter family receptor
ABC16_RS02420	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ABC16_RS02425	COG1660	Displays ATPase and GTPase activities
ABC16_RS02435	COG2010	Cytochrome c
ABC16_RS02435	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ABC16_RS02440	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
ABC16_RS02450	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ABC16_RS02455	COG1137	ATPase activity
ABC16_RS02470	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ABC16_RS02480	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ABC16_RS02515	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ABC16_RS02520	COG3568	Endonuclease Exonuclease Phosphatase
ABC16_RS02525	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ABC16_RS02555	COG0154	amidase activity
ABC16_RS02565	COG1414	Transcriptional regulator
ABC16_RS02575	COG1024	Enoyl-CoA hydratase
ABC16_RS02575	COG1250	3-hydroxyacyl-CoA dehydrogenase
ABC16_RS02585	COG2132	Multicopper oxidase
ABC16_RS02615	COG1250	3-hydroxyacyl-CoA dehydrogenase
ABC16_RS02640	COG1024	Enoyl-CoA hydratase
ABC16_RS02645	COG1024	Enoyl-CoA hydratase
ABC16_RS02650	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ABC16_RS02670	COG0601	transmembrane transport
ABC16_RS02675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABC16_RS02680	COG4172	Belongs to the ABC transporter superfamily
ABC16_RS02690	COG2195	Cleaves the N-terminal amino acid of tripeptides
ABC16_RS02700	COG0210	DNA helicase
ABC16_RS02705	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ABC16_RS02710	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ABC16_RS02720	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ABC16_RS02725	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ABC16_RS02730	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ABC16_RS02735	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ABC16_RS02740	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ABC16_RS02745	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ABC16_RS02755	COG0356	it plays a direct role in the translocation of protons across the membrane
ABC16_RS02780	COG1024	Enoyl-CoA hydratase
ABC16_RS02785	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ABC16_RS02790	COG3634	alkyl hydroperoxide reductase activity
ABC16_RS02800	COG0037	tRNA processing
ABC16_RS02810	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ABC16_RS02815	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ABC16_RS02820	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ABC16_RS02825	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ABC16_RS02830	COG2967	ApaG domain
ABC16_RS02835	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ABC16_RS02840	COG0546	phosphoglycolate phosphatase activity
ABC16_RS02850	COG0512	Glutamine amidotransferase of anthranilate synthase
ABC16_RS02855	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ABC16_RS02860	COG0134	indole-3-glycerol-phosphate synthase activity
ABC16_RS02880	COG1960	acyl-CoA dehydrogenase activity
ABC16_RS02885	COG0583	DNA-binding transcription factor activity
ABC16_RS02900	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ABC16_RS02905	COG0259	pyridoxamine-phosphate oxidase activity
ABC16_RS02915	COG2814	Major facilitator Superfamily
ABC16_RS02920	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ABC16_RS02925	COG2188	Transcriptional regulator
ABC16_RS02930	COG0318	PFAM AMP-dependent synthetase and ligase
ABC16_RS02950	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ABC16_RS02960	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ABC16_RS02975	COG1215	transferase activity, transferring glycosyl groups
ABC16_RS02985	COG0601	transmembrane transport
ABC16_RS03000	COG0488	(ABC) transporter
ABC16_RS03020	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
ABC16_RS03025	COG2894	cell division
ABC16_RS03030	COG0850	regulation of cytokinetic process
ABC16_RS03035	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ABC16_RS03040	COG1271	oxidase subunit
ABC16_RS03075	COG2979	Protein of unknown function (DUF533)
ABC16_RS03095	COG1388	LysM domain
ABC16_RS03095	COG0741	lytic transglycosylase activity
ABC16_RS03100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ABC16_RS03105	COG2226	methyltransferase
ABC16_RS03110	COG0328	RNA-DNA hybrid ribonuclease activity
ABC16_RS03160	COG2030	dehydratase
ABC16_RS03165	COG0183	Belongs to the thiolase family
ABC16_RS03210	COG1960	acyl-CoA dehydrogenase activity
ABC16_RS03225	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC16_RS03230	COG1028	Short-chain dehydrogenase reductase Sdr
ABC16_RS03245	COG2718	Belongs to the UPF0229 family
ABC16_RS03250	COG2719	SpoVR family
ABC16_RS03275	COG2188	Transcriptional regulator
ABC16_RS03290	COG0633	Ferredoxin
ABC16_RS03300	COG0829	nickel cation binding
ABC16_RS03305	COG0831	urea catabolic process
ABC16_RS03315	COG0832	Belongs to the urease beta subunit family
ABC16_RS03320	COG0804	urea catabolic process
ABC16_RS03330	COG0830	nickel cation binding
ABC16_RS03335	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ABC16_RS03355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABC16_RS03360	COG0601	transmembrane transport
ABC16_RS03365	COG0747	negative chemotaxis
ABC16_RS03375	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ABC16_RS03380	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ABC16_RS03390	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ABC16_RS03400	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
ABC16_RS03405	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ABC16_RS03410	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ABC16_RS03425	COG0438	transferase activity, transferring glycosyl groups
ABC16_RS03440	COG0438	transferase activity, transferring glycosyl groups
ABC16_RS03445	COG0438	transferase activity, transferring glycosyl groups
ABC16_RS03450	COG0166	Belongs to the GPI family
ABC16_RS03465	COG0277	FAD linked oxidase domain protein
ABC16_RS03470	COG0745	RESPONSE REGULATOR receiver
ABC16_RS03475	COG0642	Histidine kinase
ABC16_RS03480	COG1368	sulfuric ester hydrolase activity
ABC16_RS03490	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
ABC16_RS03515	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ABC16_RS03525	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
ABC16_RS03530	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ABC16_RS03540	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ABC16_RS03545	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ABC16_RS03550	COG0193	aminoacyl-tRNA hydrolase activity
ABC16_RS03560	COG0012	GTP binding
ABC16_RS03565	COG0582	viral genome integration into host DNA
ABC16_RS03590	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ABC16_RS03655	COG0745	RESPONSE REGULATOR receiver
ABC16_RS03670	COG1309	transcriptional regulator
ABC16_RS03700	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABC16_RS03710	COG0405	Gamma-glutamyltransferase
ABC16_RS03725	COG1280	lysine exporter protein (LysE YggA)
ABC16_RS03785	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
ABC16_RS03790	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ABC16_RS03800	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ABC16_RS03805	COG0513	Belongs to the DEAD box helicase family
ABC16_RS03815	COG0617	tRNA 3'-terminal CCA addition
ABC16_RS03830	COG0477	Major facilitator Superfamily
ABC16_RS03840	COG0583	DNA-binding transcription factor activity
ABC16_RS03855	COG1950	PFAM Membrane protein of
ABC16_RS03860	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ABC16_RS03875	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ABC16_RS03885	COG1560	Kdo2-lipid A biosynthetic process
ABC16_RS03890	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ABC16_RS03900	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ABC16_RS03910	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
ABC16_RS03920	COG0803	Belongs to the bacterial solute-binding protein 9 family
ABC16_RS03940	COG0735	belongs to the Fur family
ABC16_RS03945	COG0523	cobalamin synthesis protein
ABC16_RS03955	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ABC16_RS03960	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ABC16_RS03970	COG2096	Adenosyltransferase
ABC16_RS03985	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ABC16_RS03990	COG2084	Dehydrogenase
ABC16_RS04040	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ABC16_RS04045	COG0129	dihydroxy-acid dehydratase activity
ABC16_RS04050	COG4654	Cytochrome c, class I
ABC16_RS04055	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ABC16_RS04105	COG1473	amidohydrolase
ABC16_RS04110	COG0418	dihydroorotase activity
ABC16_RS04115	COG0488	(ABC) transporter
ABC16_RS04125	COG2001	Belongs to the MraZ family
ABC16_RS04130	COG0275	rRNA processing
ABC16_RS04135	COG3116	cell division
ABC16_RS04145	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ABC16_RS04150	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ABC16_RS04155	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ABC16_RS04165	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ABC16_RS04170	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ABC16_RS04175	COG1181	Belongs to the D-alanine--D-alanine ligase family
ABC16_RS04180	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ABC16_RS04190	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ABC16_RS04195	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ABC16_RS04205	COG0739	heme binding
ABC16_RS04210	COG0653	protein targeting
ABC16_RS04230	COG1028	Short-chain dehydrogenase reductase Sdr
ABC16_RS04235	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABC16_RS04240	COG1522	sequence-specific DNA binding
ABC16_RS04260	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ABC16_RS04270	COG0557	exoribonuclease II activity
ABC16_RS04275	COG3150	esterase
ABC16_RS04280	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ABC16_RS04285	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ABC16_RS04290	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ABC16_RS04295	COG0511	ligase activity, forming carbon-carbon bonds
ABC16_RS04300	COG0439	Biotin carboxylase
ABC16_RS04305	COG2264	protein methyltransferase activity
ABC16_RS04315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ABC16_RS04340	COG1696	Membrane protein involved in D-alanine export
ABC16_RS04345	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ABC16_RS04380	COG1522	sequence-specific DNA binding
ABC16_RS04395	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ABC16_RS04400	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ABC16_RS04400	COG1042	CoA-binding domain protein
ABC16_RS04400	COG0045	succinate-CoA ligase (ADP-forming) activity
ABC16_RS04415	COG1802	Transcriptional regulator
ABC16_RS04420	COG3069	C4-dicarboxylate transmembrane transporter activity
ABC16_RS04425	COG0513	Belongs to the DEAD box helicase family
ABC16_RS04430	COG0346	lactoylglutathione lyase activity
ABC16_RS04435	COG1335	isochorismatase
ABC16_RS04440	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABC16_RS04445	COG1116	anion transmembrane transporter activity
ABC16_RS04460	COG3028	Belongs to the UPF0307 family
ABC16_RS04465	COG0312	modulator of DNA gyrase
ABC16_RS04470	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ABC16_RS04475	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ABC16_RS04480	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ABC16_RS04485	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ABC16_RS04495	COG0316	Belongs to the HesB IscA family
ABC16_RS04500	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
ABC16_RS04515	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ABC16_RS04525	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ABC16_RS04530	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ABC16_RS04545	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ABC16_RS04545	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ABC16_RS04575	COG0583	DNA-binding transcription factor activity
ABC16_RS04580	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC16_RS04615	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
ABC16_RS04625	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ABC16_RS04630	COG1845	cytochrome c oxidase, subunit III
ABC16_RS04635	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ABC16_RS04640	COG0640	Transcriptional regulator
ABC16_RS04660	COG3220	belongs to the UPF0276 family
ABC16_RS04705	COG1666	GTP binding
ABC16_RS04740	COG0312	modulator of DNA gyrase
ABC16_RS04745	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ABC16_RS04750	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
ABC16_RS04750	COG3210	domain, Protein
ABC16_RS04750	COG3210	domain, Protein
ABC16_RS04750	COG3064	Membrane
ABC16_RS04750	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
ABC16_RS04750	COG3064	Membrane
ABC16_RS04755	COG0277	FAD linked oxidase domain protein
ABC16_RS04760	COG0277	FAD linked oxidase domain protein
ABC16_RS04765	COG0277	FAD linked oxidase domain protein
ABC16_RS04770	COG0247	lactate metabolic process
ABC16_RS04775	COG2819	hydrolase of the alpha beta superfamily
ABC16_RS04800	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ABC16_RS04820	COG0583	DNA-binding transcription factor activity
ABC16_RS04825	COG0482	sulfurtransferase activity
ABC16_RS04830	COG0730	response to heat
ABC16_RS04835	COG0625	glutathione transferase activity
ABC16_RS04840	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ABC16_RS04845	COG3909	cytochrome
ABC16_RS04885	COG0154	amidase activity
ABC16_RS04890	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC16_RS04895	COG1024	Enoyl-CoA hydratase
ABC16_RS04910	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABC16_RS04925	COG1028	Short-chain dehydrogenase reductase Sdr
ABC16_RS04930	COG1414	Transcriptional regulator
ABC16_RS04940	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ABC16_RS04945	COG0251	oxidation-reduction process
ABC16_RS04950	COG0559	Belongs to the binding-protein-dependent transport system permease family
ABC16_RS04970	COG1902	pentaerythritol trinitrate reductase activity
ABC16_RS04985	COG0583	DNA-binding transcription factor activity
ABC16_RS04995	COG0590	tRNA wobble adenosine to inosine editing
ABC16_RS05000	COG2807	transmembrane transport
ABC16_RS05020	COG0154	amidase activity
ABC16_RS05025	COG0307	riboflavin synthase, alpha
ABC16_RS05030	COG3181	Tripartite tricarboxylate transporter family receptor
ABC16_RS05035	COG1522	sequence-specific DNA binding
ABC16_RS05045	COG0318	PFAM AMP-dependent synthetase and ligase
ABC16_RS05055	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABC16_RS05075	COG1063	alcohol dehydrogenase
ABC16_RS05100	COG1418	mRNA catabolic process
ABC16_RS05105	COG1448	Aminotransferase
ABC16_RS05110	COG0583	DNA-binding transcription factor activity
ABC16_RS05120	COG0477	Major facilitator Superfamily
ABC16_RS05125	COG1028	Short-chain dehydrogenase reductase Sdr
ABC16_RS05140	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ABC16_RS05145	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ABC16_RS05150	COG0583	DNA-binding transcription factor activity
ABC16_RS05210	COG1028	Short-chain dehydrogenase reductase Sdr
ABC16_RS05215	COG1309	transcriptional regulator
ABC16_RS05225	COG2982	Protein involved in outer membrane biogenesis
ABC16_RS05230	COG2818	Glycosylase
ABC16_RS05250	COG1653	transport
ABC16_RS05260	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ABC16_RS05265	COG3842	ATPase activity
ABC16_RS05270	COG0395	ABC-type sugar transport system, permease component
ABC16_RS05275	COG1175	transmembrane transport
ABC16_RS05295	COG3181	Tripartite tricarboxylate transporter family receptor
ABC16_RS05300	COG2186	Transcriptional regulator
ABC16_RS05330	COG1454	alcohol dehydrogenase
ABC16_RS05350	COG2011	ABC-type metal ion transport system permease component
ABC16_RS05355	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ABC16_RS05360	COG1501	Belongs to the glycosyl hydrolase 31 family
ABC16_RS05385	COG0318	PFAM AMP-dependent synthetase and ligase
ABC16_RS05390	COG1473	amidohydrolase
ABC16_RS05400	COG2855	membrane
ABC16_RS05410	COG2239	Acts as a magnesium transporter
ABC16_RS05430	COG3181	Tripartite tricarboxylate transporter family receptor
ABC16_RS05440	COG1722	exodeoxyribonuclease VII activity
ABC16_RS05445	COG0142	geranyltranstransferase activity
ABC16_RS05450	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ABC16_RS05455	COG1469	GTP cyclohydrolase I activity
ABC16_RS05460	COG0360	Binds together with S18 to 16S ribosomal RNA
ABC16_RS05465	COG2965	DNA replication, synthesis of RNA primer
ABC16_RS05470	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ABC16_RS05475	COG0359	binds to the 23S rRNA
ABC16_RS05485	COG0305	Participates in initiation and elongation during chromosome replication
ABC16_RS05495	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ABC16_RS05500	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ABC16_RS05505	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ABC16_RS05510	COG3737	Protein of unknown function (DUF498/DUF598)
ABC16_RS05515	COG0436	Aminotransferase
ABC16_RS05540	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ABC16_RS05570	COG0268	Binds directly to 16S ribosomal RNA
ABC16_RS05580	COG0728	peptidoglycan biosynthetic process
ABC16_RS05590	COG0563	adenylate kinase activity
ABC16_RS05595	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ABC16_RS05600	COG2835	tetraacyldisaccharide 4'-kinase activity
ABC16_RS05605	COG1663	tetraacyldisaccharide 4'-kinase activity
ABC16_RS05610	COG0848	biopolymer transport protein
ABC16_RS05615	COG0811	peptide transport
ABC16_RS05625	COG1570	exodeoxyribonuclease VII activity
ABC16_RS05630	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ABC16_RS05635	COG0038	chloride channel
ABC16_RS05640	COG0183	Belongs to the thiolase family
ABC16_RS05650	COG1278	Cold shock
ABC16_RS05655	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ABC16_RS05665	COG4953	penicillin-binding protein 1C
ABC16_RS05670	COG0542	response to heat
ABC16_RS05675	COG2995	paraquat-inducible protein a
ABC16_RS05680	COG3008	intermembrane lipid transfer
ABC16_RS05680	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ABC16_RS05690	COG0506	proline dehydrogenase activity
ABC16_RS05690	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ABC16_RS05690	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ABC16_RS05725	COG2271	Major facilitator Superfamily
ABC16_RS05730	COG1309	transcriptional regulator
ABC16_RS05740	COG3468	outer membrane autotransporter barrel domain protein
ABC16_RS05770	COG0477	Major facilitator Superfamily
ABC16_RS05780	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ABC16_RS05785	COG1845	cytochrome c oxidase, subunit III
ABC16_RS05790	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ABC16_RS05800	COG1028	Short-chain dehydrogenase reductase Sdr
ABC16_RS05820	COG0789	Transcriptional regulator
ABC16_RS05845	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ABC16_RS05850	COG0697	spore germination
ABC16_RS05860	COG0678	peroxiredoxin activity
ABC16_RS05870	COG0412	Dienelactone hydrolase
ABC16_RS05880	COG0315	cyclic pyranopterin monophosphate synthase activity
ABC16_RS05895	COG0521	Mo-molybdopterin cofactor biosynthetic process
ABC16_RS05900	COG0303	'Molybdopterin
ABC16_RS05905	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ABC16_RS05925	COG0165	Argininosuccinate lyase
ABC16_RS05930	COG0668	transmembrane transport
ABC16_RS05975	COG0747	negative chemotaxis
ABC16_RS05980	COG0601	transmembrane transport
ABC16_RS05985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABC16_RS05990	COG1162	GTPase activity
ABC16_RS05995	COG0501	Belongs to the peptidase M48B family
ABC16_RS06000	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ABC16_RS06010	COG3327	negative regulation of DNA-templated transcription, initiation
ABC16_RS06015	COG3396	Phenylacetate-CoA oxygenase
ABC16_RS06020	COG3460	Phenylacetate-CoA oxygenase
ABC16_RS06025	COG3396	Phenylacetate-CoA oxygenase
ABC16_RS06030	COG2151	metal-sulfur cluster biosynthetic enzyme
ABC16_RS06035	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ABC16_RS06045	COG1012	belongs to the aldehyde dehydrogenase family
ABC16_RS06050	COG1024	Enoyl-CoA hydratase
ABC16_RS06055	COG2050	protein possibly involved in aromatic compounds catabolism
ABC16_RS06065	COG3539	Fimbrial protein
ABC16_RS06085	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ABC16_RS06090	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ABC16_RS06090	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ABC16_RS06095	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ABC16_RS06100	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ABC16_RS06100	COG0047	phosphoribosylformylglycinamidine synthase activity
ABC16_RS06105	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
ABC16_RS06105	COG3210	domain, Protein
ABC16_RS06105	COG3064	Membrane
ABC16_RS06130	COG0235	Class ii aldolase
ABC16_RS06135	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ABC16_RS06140	COG0720	synthase
ABC16_RS06145	COG0602	queuosine metabolic process
ABC16_RS06170	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ABC16_RS06205	COG3181	Tripartite tricarboxylate transporter family receptor
ABC16_RS06235	COG3842	ATPase activity
ABC16_RS06245	COG0395	ABC-type sugar transport system, permease component
ABC16_RS06275	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABC16_RS06280	COG0420	3'-5' exonuclease activity
ABC16_RS06325	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ABC16_RS06325	COG0519	Catalyzes the synthesis of GMP from XMP
ABC16_RS06340	COG3550	peptidyl-serine autophosphorylation
ABC16_RS06350	COG0477	Major facilitator Superfamily
ABC16_RS06365	COG1228	amidohydrolase
ABC16_RS06375	COG1116	anion transmembrane transporter activity
ABC16_RS06380	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABC16_RS06420	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ABC16_RS06440	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ABC16_RS06470	COG2814	Major facilitator Superfamily
ABC16_RS06485	COG1280	lysine exporter protein (LysE YggA)
ABC16_RS06500	COG0747	negative chemotaxis
ABC16_RS06505	COG0601	transmembrane transport
ABC16_RS06510	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABC16_RS06515	COG4172	Belongs to the ABC transporter superfamily
ABC16_RS06520	COG1609	Transcriptional regulator
ABC16_RS06550	COG0586	Pfam SNARE associated Golgi protein
ABC16_RS06565	COG0500	methyltransferase
ABC16_RS06580	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ABC16_RS06590	COG0756	dUTP diphosphatase activity
ABC16_RS06605	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ABC16_RS06610	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ABC16_RS06615	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ABC16_RS06620	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ABC16_RS06620	COG0072	phenylalanine-tRNA ligase activity
ABC16_RS06625	COG0776	regulation of translation
ABC16_RS06695	COG0540	Belongs to the ATCase OTCase family
ABC16_RS06700	COG2974	May be involved in recombination
ABC16_RS06710	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC16_RS06715	COG0583	DNA-binding transcription factor activity
ABC16_RS06735	COG1028	Short-chain dehydrogenase reductase Sdr
ABC16_RS06750	COG3842	ATPase activity
ABC16_RS06755	COG1024	Enoyl-CoA hydratase
ABC16_RS06755	COG1250	3-hydroxyacyl-CoA dehydrogenase
ABC16_RS06775	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ABC16_RS06780	COG2137	regulation of response to DNA damage stimulus
ABC16_RS06790	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ABC16_RS06800	COG0045	succinate-CoA ligase (ADP-forming) activity
ABC16_RS06805	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ABC16_RS06810	COG0861	Integral membrane protein TerC family
ABC16_RS06815	COG0861	Integral membrane protein TerC family
ABC16_RS06820	COG0181	hydroxymethylbilane synthase activity
ABC16_RS06880	COG4964	Belongs to the GSP D family
ABC16_RS06910	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ABC16_RS06920	COG0583	DNA-binding transcription factor activity
ABC16_RS06930	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABC16_RS06935	COG4311	Sarcosine oxidase, delta subunit
ABC16_RS06940	COG0446	pyridine nucleotide-disulphide oxidoreductase
ABC16_RS06940	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ABC16_RS06975	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ABC16_RS06980	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ABC16_RS06985	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ABC16_RS06990	COG0735	belongs to the Fur family
ABC16_RS06995	COG0497	DNA recombination
ABC16_RS07000	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ABC16_RS07005	COG1420	regulation of RNA biosynthetic process
ABC16_RS07010	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ABC16_RS07020	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ABC16_RS07030	COG0443	Heat shock 70 kDa protein
ABC16_RS07040	COG0612	Peptidase, M16
ABC16_RS07060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ABC16_RS07105	COG0745	RESPONSE REGULATOR receiver
ABC16_RS07115	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
ABC16_RS07120	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
ABC16_RS07125	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ABC16_RS07140	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ABC16_RS07160	COG1193	negative regulation of DNA recombination
ABC16_RS07165	COG0492	ferredoxin-NADP+ reductase activity
ABC16_RS07170	COG1674	ftsk spoiiie
ABC16_RS07175	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ABC16_RS07180	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ABC16_RS07185	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ABC16_RS07210	COG3706	GGDEF domain
ABC16_RS07230	COG2814	Major facilitator Superfamily
ABC16_RS07260	COG3486	L-lysine 6-monooxygenase (NADPH) activity
ABC16_RS07275	COG1028	Short-chain dehydrogenase reductase Sdr
ABC16_RS07285	COG3022	response to hydroperoxide
ABC16_RS07295	COG1289	transmembrane transporter activity
ABC16_RS07300	COG3023	N-Acetylmuramoyl-L-alanine amidase
ABC16_RS07310	COG0424	maF-like protein
ABC16_RS07315	COG1399	metal-binding, possibly nucleic acid-binding protein
ABC16_RS07320	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ABC16_RS07325	COG0416	fatty acid biosynthetic process
ABC16_RS07330	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ABC16_RS07345	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ABC16_RS07350	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ABC16_RS07375	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ABC16_RS07380	COG0481	GTPase activity
ABC16_RS07385	COG0681	Belongs to the peptidase S26 family
ABC16_RS07390	COG0571	ribonuclease III activity
ABC16_RS07395	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ABC16_RS07400	COG1381	Involved in DNA repair and RecF pathway recombination
ABC16_RS07410	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ABC16_RS07420	COG3181	Tripartite tricarboxylate transporter family receptor
ABC16_RS07425	COG0670	Belongs to the BI1 family
ABC16_RS07440	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ABC16_RS07450	COG0583	DNA-binding transcription factor activity
ABC16_RS07465	COG0583	DNA-binding transcription factor activity
ABC16_RS07480	COG0791	NLP P60 protein
ABC16_RS07485	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ABC16_RS07490	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ABC16_RS07495	COG3193	protein, possibly involved in utilization of glycolate and propanediol
ABC16_RS07505	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ABC16_RS07510	COG0697	spore germination
ABC16_RS07515	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
ABC16_RS07530	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ABC16_RS07560	COG1446	asparaginase
ABC16_RS07565	COG4172	Belongs to the ABC transporter superfamily
ABC16_RS07570	COG0747	negative chemotaxis
ABC16_RS07580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABC16_RS07605	COG0504	CTP synthase activity
ABC16_RS07610	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ABC16_RS07620	COG0148	phosphopyruvate hydratase activity
ABC16_RS07625	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ABC16_RS07655	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ABC16_RS07665	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ABC16_RS07690	COG1981	membrane
ABC16_RS07705	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ABC16_RS07730	COG0039	L-malate dehydrogenase activity
ABC16_RS07735	COG2188	Transcriptional regulator
ABC16_RS07740	COG2009	succinate dehydrogenase
ABC16_RS07745	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ABC16_RS07750	COG1053	succinate dehydrogenase
ABC16_RS07755	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ABC16_RS07760	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
ABC16_RS07765	COG0372	Belongs to the citrate synthase family
ABC16_RS07785	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ABC16_RS07785	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ABC16_RS07795	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ABC16_RS07800	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
ABC16_RS07815	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ABC16_RS07820	COG3842	ATPase activity
ABC16_RS07825	COG1176	ABC-type spermidine putrescine transport system, permease component I
ABC16_RS07830	COG1177	transmembrane transport
ABC16_RS07855	COG1960	acyl-CoA dehydrogenase activity
ABC16_RS07860	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ABC16_RS07865	COG0704	Plays a role in the regulation of phosphate uptake
ABC16_RS07875	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
ABC16_RS07880	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ABC16_RS07880	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ABC16_RS07885	COG1643	Atp-dependent helicase
ABC16_RS07900	COG0438	transferase activity, transferring glycosyl groups
ABC16_RS07905	COG0726	polysaccharide deacetylase
ABC16_RS07910	COG0463	Glycosyl transferase, family 2
ABC16_RS07915	COG0438	transferase activity, transferring glycosyl groups
ABC16_RS07920	COG2194	sulfuric ester hydrolase activity
ABC16_RS07945	COG0859	PFAM glycosyl transferase family 9
ABC16_RS07950	COG1132	(ABC) transporter
ABC16_RS07965	COG0077	Prephenate dehydratase
ABC16_RS07970	COG1530	ribonuclease E activity
ABC16_RS08010	COG3468	outer membrane autotransporter barrel domain protein
ABC16_RS08015	COG0424	maF-like protein
ABC16_RS08020	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ABC16_RS08025	COG0799	negative regulation of ribosome biogenesis
ABC16_RS08030	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ABC16_RS08035	COG0408	coproporphyrinogen oxidase activity
ABC16_RS08040	COG0151	Belongs to the GarS family
ABC16_RS08045	COG0217	transcriptional regulatory protein
ABC16_RS08050	COG0433	COG0433 Predicted ATPase
ABC16_RS08055	COG1115	amino acid carrier protein
ABC16_RS08060	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ABC16_RS08070	COG1012	belongs to the aldehyde dehydrogenase family
ABC16_RS08095	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ABC16_RS08110	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABC16_RS08120	COG0747	negative chemotaxis
ABC16_RS08130	COG0473	3-isopropylmalate dehydrogenase activity
ABC16_RS08135	COG2814	Major facilitator Superfamily
ABC16_RS08140	COG1566	PFAM secretion protein HlyD family protein
ABC16_RS08150	COG1846	Transcriptional regulator
ABC16_RS08160	COG0697	spore germination
ABC16_RS08170	COG0501	Belongs to the peptidase M48B family
ABC16_RS08190	COG0583	DNA-binding transcription factor activity
ABC16_RS08195	COG3842	ATPase activity
ABC16_RS08200	COG1178	ABC-type Fe3 transport system permease component
ABC16_RS08205	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ABC16_RS08210	COG1840	ABC-type Fe3 transport system, periplasmic component
ABC16_RS08215	COG0492	ferredoxin-NADP+ reductase activity
ABC16_RS08235	COG2233	PERMEase
ABC16_RS08240	COG0840	transmembrane signaling receptor activity
ABC16_RS08245	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ABC16_RS08275	COG4789	Type iii secretion
ABC16_RS08340	COG4669	(LipO)protein
ABC16_RS08375	COG4790	Type iii secretion
ABC16_RS08380	COG4794	Type iii secretion
ABC16_RS08385	COG4791	protein targeting
ABC16_RS08390	COG4792	protein secretion
ABC16_RS08405	COG1595	DNA-templated transcription, initiation
ABC16_RS08425	COG2208	phosphoserine phosphatase activity
ABC16_RS08425	COG2770	Histidine kinase
ABC16_RS08435	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ABC16_RS08440	COG2172	sigma factor antagonist activity
ABC16_RS08445	COG1366	Belongs to the anti-sigma-factor antagonist family
ABC16_RS08450	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ABC16_RS08480	COG2358	TRAP transporter, solute receptor (TAXI family
ABC16_RS08485	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ABC16_RS08515	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ABC16_RS08525	COG2252	PERMEase
ABC16_RS08530	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ABC16_RS08540	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ABC16_RS08545	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ABC16_RS08575	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ABC16_RS08580	COG0789	Transcriptional regulator
ABC16_RS08590	COG0678	peroxiredoxin activity
ABC16_RS08590	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ABC16_RS08600	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ABC16_RS08605	COG0584	glycerophosphoryl diester phosphodiesterase
ABC16_RS08610	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ABC16_RS08620	COG4181	ATPase activity
ABC16_RS08630	COG2823	Periplasmic or secreted lipoprotein
ABC16_RS08640	COG3237	CsbD-like
ABC16_RS08645	COG1181	Belongs to the D-alanine--D-alanine ligase family
ABC16_RS08645	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ABC16_RS08650	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ABC16_RS08650	COG0189	ligase activity
ABC16_RS08670	COG2833	Protein of unknown function (DUF455)
ABC16_RS08675	COG2951	lytic endotransglycosylase activity
ABC16_RS08695	COG1522	sequence-specific DNA binding
ABC16_RS08705	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ABC16_RS08710	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ABC16_RS08715	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ABC16_RS08720	COG0196	riboflavin kinase activity
ABC16_RS08725	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ABC16_RS08745	COG0210	DNA helicase
ABC16_RS08750	COG4771	TonB-dependent receptor
ABC16_RS08755	COG0488	(ABC) transporter
ABC16_RS08760	COG2890	protein-(glutamine-N5) methyltransferase activity
ABC16_RS08765	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ABC16_RS08770	COG2171	N-acyltransferase activity
ABC16_RS08805	COG1278	Cold shock
ABC16_RS08825	COG0544	peptidyl-prolyl cis-trans isomerase activity
ABC16_RS08830	COG0740	serine-type endopeptidase activity
ABC16_RS08835	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ABC16_RS08840	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ABC16_RS08845	COG0583	DNA-binding transcription factor activity
ABC16_RS08850	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC16_RS08865	COG1024	Enoyl-CoA hydratase
ABC16_RS08875	COG0183	Belongs to the thiolase family
ABC16_RS08880	COG1028	Short-chain dehydrogenase reductase Sdr
ABC16_RS08885	COG1960	acyl-CoA dehydrogenase activity
ABC16_RS08900	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ABC16_RS08930	COG3468	outer membrane autotransporter barrel domain protein
ABC16_RS08935	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ABC16_RS08945	COG0556	nucleotide-excision repair
ABC16_RS08950	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ABC16_RS08960	COG1104	cysteine desulfurase activity
ABC16_RS08965	COG0822	iron-sulfur transferase activity
ABC16_RS08970	COG0316	Belongs to the HesB IscA family
ABC16_RS08975	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ABC16_RS08980	COG0443	Heat shock 70 kDa protein
ABC16_RS08985	COG0633	Ferredoxin
ABC16_RS09005	COG1024	Enoyl-CoA hydratase
ABC16_RS09020	COG3395	kinase activity
ABC16_RS09025	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ABC16_RS09040	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ABC16_RS09050	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABC16_RS09075	COG0747	negative chemotaxis
ABC16_RS09080	COG0601	transmembrane transport
ABC16_RS09085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABC16_RS09090	COG4172	Belongs to the ABC transporter superfamily
ABC16_RS09095	COG0154	amidase activity
ABC16_RS09140	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ABC16_RS09145	COG0425	Belongs to the sulfur carrier protein TusA family
ABC16_RS09155	COG0228	four-way junction DNA binding
ABC16_RS09160	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ABC16_RS09165	COG0336	Belongs to the RNA methyltransferase TrmD family
ABC16_RS09170	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ABC16_RS09190	COG0642	Histidine kinase
ABC16_RS09205	COG0525	valine-tRNA ligase activity
ABC16_RS09210	COG0105	UTP biosynthetic process
ABC16_RS09215	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ABC16_RS09225	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ABC16_RS09230	COG0124	histidyl-tRNA synthetase
ABC16_RS09235	COG2976	Protein conserved in bacteria
ABC16_RS09240	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ABC16_RS09245	COG1160	GTP binding
ABC16_RS09250	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ABC16_RS09255	COG1923	regulation of RNA biosynthetic process
ABC16_RS09260	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ABC16_RS09265	COG0330	HflC and HflK could
ABC16_RS09270	COG0330	HflC and HflK could
ABC16_RS09275	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ABC16_RS09280	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ABC16_RS09285	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ABC16_RS09290	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ABC16_RS09300	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ABC16_RS09330	COG0628	permease
ABC16_RS09335	COG0842	Transport permease protein
ABC16_RS09340	COG1131	(ABC) transporter
ABC16_RS09410	COG0156	8-amino-7-oxononanoate synthase activity
ABC16_RS09420	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ABC16_RS09420	COG4106	trans-aconitate 2-methyltransferase activity
ABC16_RS09425	COG1380	Effector of murein hydrolase LrgA
ABC16_RS09445	COG3284	Transcriptional regulator
ABC16_RS09450	COG1012	belongs to the aldehyde dehydrogenase family
ABC16_RS09465	COG2733	membrane
ABC16_RS09470	COG0583	DNA-binding transcription factor activity
ABC16_RS09475	COG0384	phenazine biosynthesis protein PhzF
ABC16_RS09480	COG5507	3-demethylubiquinone-9 3-methyltransferase
ABC16_RS09485	COG2169	Transcriptional regulator
ABC16_RS09515	COG0659	secondary active sulfate transmembrane transporter activity
ABC16_RS09540	COG1132	(ABC) transporter
ABC16_RS09585	COG2207	Transcriptional regulator
ABC16_RS09720	COG2346	COG2346, Truncated hemoglobins
ABC16_RS09765	COG0183	Belongs to the thiolase family
ABC16_RS09780	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC16_RS09785	COG0633	Ferredoxin
ABC16_RS09795	COG1024	Enoyl-CoA hydratase
ABC16_RS09805	COG4638	Rieske (2fe-2S)
ABC16_RS09815	COG0559	Belongs to the binding-protein-dependent transport system permease family
ABC16_RS09835	COG2224	Isocitrate lyase
ABC16_RS09840	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ABC16_RS09840	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ABC16_RS09855	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ABC16_RS09860	COG0322	excinuclease ABC activity
ABC16_RS09865	COG1472	Belongs to the glycosyl hydrolase 3 family
ABC16_RS09870	COG0736	holo-[acyl-carrier-protein] synthase activity
ABC16_RS09875	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ABC16_RS09885	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ABC16_RS09890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ABC16_RS09915	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
ABC16_RS09930	COG2032	superoxide dismutase activity
ABC16_RS09945	COG1024	Enoyl-CoA hydratase
ABC16_RS09955	COG1802	Transcriptional regulator
ABC16_RS09965	COG0183	Belongs to the thiolase family
ABC16_RS09970	COG1942	4-Oxalocrotonate Tautomerase
ABC16_RS09980	COG4176	ABC-type proline glycine betaine transport system permease component
ABC16_RS09995	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ABC16_RS10000	COG2814	Major facilitator Superfamily
ABC16_RS10005	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ABC16_RS10010	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ABC16_RS10040	COG2814	Major facilitator Superfamily
ABC16_RS10045	COG0495	leucyl-tRNA aminoacylation
ABC16_RS10060	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ABC16_RS10070	COG0154	amidase activity
ABC16_RS10075	COG1250	3-hydroxyacyl-CoA dehydrogenase
ABC16_RS10130	COG0427	acetyl-CoA hydrolase
ABC16_RS10135	COG0583	DNA-binding transcription factor activity
ABC16_RS10155	COG0730	response to heat
ABC16_RS10160	COG0697	spore germination
ABC16_RS10195	COG2885	chlorophyll binding
ABC16_RS10220	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ABC16_RS10225	COG3384	dioxygenase
ABC16_RS10240	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ABC16_RS10245	COG3474	cytochrome
ABC16_RS10255	COG1595	DNA-templated transcription, initiation
ABC16_RS10270	COG2204	response regulator
ABC16_RS10310	COG4964	Belongs to the GSP D family
ABC16_RS10360	COG1846	Transcriptional regulator
ABC16_RS10365	COG4172	Belongs to the ABC transporter superfamily
ABC16_RS10370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABC16_RS10375	COG0601	transmembrane transport
ABC16_RS10380	COG0747	negative chemotaxis
ABC16_RS10390	COG0598	Magnesium transport protein CorA
ABC16_RS10395	COG0210	DNA helicase
ABC16_RS10410	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ABC16_RS10415	COG1012	belongs to the aldehyde dehydrogenase family
ABC16_RS10420	COG0483	inositol monophosphate 1-phosphatase activity
ABC16_RS10425	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ABC16_RS10435	COG1045	serine acetyltransferase
ABC16_RS10440	COG0166	Belongs to the GPI family
ABC16_RS10455	COG2197	response regulator
ABC16_RS10460	COG1846	Transcriptional regulator
ABC16_RS10480	COG0726	polysaccharide deacetylase
ABC16_RS10480	COG1649	PFAM Uncharacterised BCR, COG1649
ABC16_RS10485	COG1215	transferase activity, transferring glycosyl groups
ABC16_RS10495	COG1902	pentaerythritol trinitrate reductase activity
ABC16_RS10520	COG0251	oxidation-reduction process
ABC16_RS10530	COG1832	CoA-binding protein
ABC16_RS10535	COG1414	Transcriptional regulator
ABC16_RS10540	COG0446	pyridine nucleotide-disulphide oxidoreductase
ABC16_RS10540	COG1902	pentaerythritol trinitrate reductase activity
ABC16_RS10550	COG3842	ATPase activity
ABC16_RS10580	COG0583	DNA-binding transcription factor activity
ABC16_RS10590	COG1028	Short-chain dehydrogenase reductase Sdr
ABC16_RS10595	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
ABC16_RS10600	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ABC16_RS10615	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ABC16_RS10615	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ABC16_RS10620	COG1250	3-hydroxyacyl-CoA dehydrogenase
ABC16_RS10645	COG0527	aspartate kinase activity
ABC16_RS10650	COG0037	tRNA processing
ABC16_RS10660	COG0825	malonyl-CoA metabolic process
ABC16_RS10670	COG0215	cysteine-tRNA ligase activity
ABC16_RS10685	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ABC16_RS10690	COG1968	undecaprenyl-diphosphatase activity
ABC16_RS10695	COG1253	flavin adenine dinucleotide binding
ABC16_RS10700	COG0483	inositol monophosphate 1-phosphatase activity
ABC16_RS10720	COG0668	transmembrane transport
ABC16_RS10745	COG0583	DNA-binding transcription factor activity
ABC16_RS10770	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ABC16_RS10785	COG2831	hemolysin activation secretion protein
ABC16_RS10790	COG3539	Fimbrial protein
ABC16_RS10795	COG3188	usher protein
ABC16_RS10800	COG3121	Chaperone
ABC16_RS10810	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
ABC16_RS10810	COG3210	domain, Protein
ABC16_RS10810	COG3064	Membrane
ABC16_RS10815	COG2197	response regulator
ABC16_RS10820	COG2205	protein histidine kinase activity
ABC16_RS10820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABC16_RS10830	COG4336	lyase activity
ABC16_RS10855	COG2010	Cytochrome c
ABC16_RS10860	COG3189	MarR family transcriptional regulator
ABC16_RS10875	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ABC16_RS10885	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ABC16_RS10885	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ABC16_RS10895	COG0028	Belongs to the TPP enzyme family
ABC16_RS10905	COG1012	belongs to the aldehyde dehydrogenase family
ABC16_RS10910	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ABC16_RS10915	COG0010	Belongs to the arginase family
ABC16_RS10920	COG1126	abc transporter atp-binding protein
ABC16_RS10930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABC16_RS10945	COG0084	hydrolase, TatD family'
ABC16_RS10950	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ABC16_RS10955	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ABC16_RS10960	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ABC16_RS10975	COG0587	DNA-directed DNA polymerase activity
ABC16_RS10985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABC16_RS10990	COG1959	2 iron, 2 sulfur cluster binding
ABC16_RS10995	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ABC16_RS10995	COG1017	nitric oxide dioxygenase activity
ABC16_RS11030	COG0488	(ABC) transporter
ABC16_RS11035	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ABC16_RS11050	COG1024	Enoyl-CoA hydratase
ABC16_RS11055	COG1619	proteins homologs of microcin C7 resistance protein MccF
ABC16_RS11060	COG0590	tRNA wobble adenosine to inosine editing
ABC16_RS11085	COG2212	antiporter activity
ABC16_RS11090	COG1863	multisubunit Na H antiporter MnhE subunit
ABC16_RS11095	COG0651	ATP synthesis coupled electron transport
ABC16_RS11100	COG1006	Multisubunit Na H antiporter MnhC subunit
ABC16_RS11105	COG2111	Na H antiporter
ABC16_RS11105	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ABC16_RS11110	COG3181	Tripartite tricarboxylate transporter family receptor
ABC16_RS11125	COG0583	DNA-binding transcription factor activity
ABC16_RS11130	COG1028	Short-chain dehydrogenase reductase Sdr
ABC16_RS11160	COG0431	NADPH-dependent FMN reductase
ABC16_RS11205	COG1028	Short-chain dehydrogenase reductase Sdr
ABC16_RS11210	COG0179	Fumarylacetoacetate (FAA) hydrolase
ABC16_RS11240	COG0625	glutathione transferase activity
ABC16_RS11245	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
ABC16_RS11250	COG2944	sequence-specific DNA binding
ABC16_RS11260	COG2197	response regulator
ABC16_RS11285	COG3119	arylsulfatase activity
ABC16_RS11320	COG0714	Associated with various cellular activities
ABC16_RS11340	COG1028	Short-chain dehydrogenase reductase Sdr
ABC16_RS11345	COG0861	Integral membrane protein TerC family
ABC16_RS11390	COG0300	oxidoreductase activity
ABC16_RS11415	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ABC16_RS11430	COG0438	transferase activity, transferring glycosyl groups
ABC16_RS11450	COG0463	Glycosyl transferase, family 2
ABC16_RS11465	COG0783	Belongs to the Dps family
ABC16_RS11480	COG0583	DNA-binding transcription factor activity
ABC16_RS11485	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ABC16_RS11500	COG0656	L-ascorbic acid biosynthetic process
ABC16_RS11510	COG0583	DNA-binding transcription factor activity
ABC16_RS11520	COG1840	ABC-type Fe3 transport system, periplasmic component
ABC16_RS11525	COG1178	ABC-type Fe3 transport system permease component
ABC16_RS11530	COG3842	ATPase activity
ABC16_RS11540	COG1741	Belongs to the pirin family
ABC16_RS11545	COG1741	Belongs to the pirin family
ABC16_RS11550	COG0583	DNA-binding transcription factor activity
ABC16_RS11555	COG2204	response regulator
ABC16_RS11565	COG0174	glutamine synthetase
ABC16_RS11570	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ABC16_RS11580	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ABC16_RS11585	COG2199	diguanylate cyclase activity
ABC16_RS11585	COG2200	EAL domain
ABC16_RS11590	COG0840	transmembrane signaling receptor activity
ABC16_RS11605	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ABC16_RS11610	COG1561	YicC-like family, N-terminal region
ABC16_RS11630	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ABC16_RS11635	COG0791	NLP P60 protein
ABC16_RS11640	COG1028	Short-chain dehydrogenase reductase Sdr
ABC16_RS11645	COG2863	cytochrome
ABC16_RS11650	COG3258	Cytochrome c
ABC16_RS11655	COG0194	GDP metabolic process
ABC16_RS11660	COG1758	RNA polymerase activity
ABC16_RS11665	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ABC16_RS11670	COG1126	abc transporter atp-binding protein
ABC16_RS11675	COG0765	amino acid transport
ABC16_RS11680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABC16_RS11700	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ABC16_RS11705	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
ABC16_RS11710	COG3539	Fimbrial protein
ABC16_RS11715	COG2850	peptidyl-arginine hydroxylation
ABC16_RS11720	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ABC16_RS11725	COG3360	Dodecin
ABC16_RS11770	COG0009	L-threonylcarbamoyladenylate synthase
ABC16_RS11775	COG2321	neutral zinc metallopeptidase
ABC16_RS11800	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ABC16_RS11805	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ABC16_RS11810	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ABC16_RS11825	COG1074	ATP-dependent DNA helicase activity
ABC16_RS11835	COG2814	Major facilitator Superfamily
ABC16_RS11845	COG1686	Belongs to the peptidase S11 family
ABC16_RS11860	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
ABC16_RS11865	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ABC16_RS11870	COG4974	Belongs to the 'phage' integrase family
ABC16_RS11875	COG0583	DNA-binding transcription factor activity
ABC16_RS11880	COG0028	Belongs to the TPP enzyme family
ABC16_RS11895	COG0028	Belongs to the TPP enzyme family
ABC16_RS11900	COG1126	abc transporter atp-binding protein
ABC16_RS11905	COG0765	amino acid transport
ABC16_RS11920	COG1414	Transcriptional regulator
ABC16_RS11925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABC16_RS11930	COG0009	L-threonylcarbamoyladenylate synthase
ABC16_RS11935	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ABC16_RS11940	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ABC16_RS11945	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ABC16_RS11955	COG2944	sequence-specific DNA binding
ABC16_RS11965	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ABC16_RS12020	COG1126	abc transporter atp-binding protein
ABC16_RS12025	COG0765	amino acid transport
ABC16_RS12030	COG0765	amino acid transport
ABC16_RS12035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABC16_RS12045	COG2423	ornithine cyclodeaminase activity
ABC16_RS12050	COG1764	response to oxidative stress
ABC16_RS12060	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ABC16_RS12065	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ABC16_RS12075	COG0189	ligase activity
ABC16_RS12080	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ABC16_RS12085	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ABC16_RS12090	COG2197	response regulator
ABC16_RS12100	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ABC16_RS12120	COG1289	transmembrane transporter activity
ABC16_RS12130	COG3022	response to hydroperoxide
ABC16_RS12145	COG0135	phosphoribosylanthranilate isomerase activity
ABC16_RS12160	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ABC16_RS12165	COG0101	tRNA pseudouridine synthase activity
ABC16_RS12175	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ABC16_RS12180	COG0473	3-isopropylmalate dehydrogenase activity
ABC16_RS12185	COG0066	3-isopropylmalate dehydratase activity
ABC16_RS12190	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ABC16_RS12200	COG1122	ATPase activity
ABC16_RS12230	COG0437	4 iron, 4 sulfur cluster binding
ABC16_RS12235	COG0243	molybdopterin cofactor binding
ABC16_RS12235	COG3383	formate dehydrogenase (NAD+) activity
ABC16_RS12265	COG0489	protein tyrosine kinase activity
ABC16_RS12270	COG0746	molybdenum cofactor guanylyltransferase activity
ABC16_RS12275	COG0303	'Molybdopterin
ABC16_RS12280	COG1763	Mo-molybdopterin cofactor biosynthetic process
ABC16_RS12290	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ABC16_RS12295	COG5001	Diguanylate cyclase
ABC16_RS12315	COG3842	ATPase activity
ABC16_RS12325	COG0406	alpha-ribazole phosphatase activity
ABC16_RS12335	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ABC16_RS12340	COG0505	Belongs to the CarA family
ABC16_RS12345	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ABC16_RS12380	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ABC16_RS12385	COG1960	acyl-CoA dehydrogenase activity
ABC16_RS12395	COG2867	negative regulation of translational initiation
ABC16_RS12405	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ABC16_RS12410	COG3706	GGDEF domain
ABC16_RS12415	COG0330	HflC and HflK could
ABC16_RS12430	COG0519	Catalyzes the synthesis of GMP from XMP
ABC16_RS12430	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ABC16_RS12440	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
ABC16_RS12445	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ABC16_RS12450	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ABC16_RS12455	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ABC16_RS12465	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ABC16_RS12470	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ABC16_RS12475	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
ABC16_RS12480	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ABC16_RS12485	COG0750	zinc metalloprotease
ABC16_RS12490	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ABC16_RS12500	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ABC16_RS12505	COG0233	cytoplasmic translational termination
ABC16_RS12510	COG0528	UMP kinase activity
ABC16_RS12515	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ABC16_RS12520	COG0052	Belongs to the universal ribosomal protein uS2 family
ABC16_RS12525	COG0024	Methionine aminopeptidase
ABC16_RS12530	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
ABC16_RS12560	COG0285	dihydrofolate synthase activity
ABC16_RS12595	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ABC16_RS12605	COG1677	Flagellar hook-basal body complex protein FliE
ABC16_RS12615	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ABC16_RS12625	COG1157	protein secretion by the type III secretion system
ABC16_RS12650	COG1580	Controls the rotational direction of flagella during chemotaxis
ABC16_RS12670	COG1338	Plays a role in the flagellum-specific transport system
ABC16_RS12690	COG0840	transmembrane signaling receptor activity
ABC16_RS12695	COG0840	transmembrane signaling receptor activity
ABC16_RS12700	COG0840	transmembrane signaling receptor activity
ABC16_RS12710	COG1256	bacterial-type flagellum assembly
ABC16_RS12720	COG1706	bacterial-type flagellum-dependent cell motility
ABC16_RS12725	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
ABC16_RS12740	COG1749	Flagellar hook protein flgE
ABC16_RS12750	COG1558	bacterial-type flagellum-dependent cell motility
ABC16_RS12755	COG1815	bacterial-type flagellum-dependent cell motility
ABC16_RS12795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABC16_RS12800	COG0765	amino acid transport
ABC16_RS12805	COG1126	abc transporter atp-binding protein
ABC16_RS12820	COG4948	Mandelate Racemase Muconate Lactonizing
ABC16_RS12825	COG3181	Tripartite tricarboxylate transporter family receptor
ABC16_RS12835	COG0066	3-isopropylmalate dehydratase activity
ABC16_RS12850	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC16_RS12860	COG3181	Tripartite tricarboxylate transporter family receptor
ABC16_RS12870	COG1802	Transcriptional regulator
ABC16_RS12885	COG0583	DNA-binding transcription factor activity
ABC16_RS12905	COG1695	Transcriptional regulator
ABC16_RS12915	COG3568	Endonuclease Exonuclease Phosphatase
ABC16_RS12920	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ABC16_RS12935	COG0392	lysyltransferase activity
ABC16_RS12975	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ABC16_RS12985	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ABC16_RS13005	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
ABC16_RS13035	COG0667	Aldo Keto reductase
ABC16_RS13050	COG2259	Doxx family
ABC16_RS13080	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC16_RS13100	COG0386	Belongs to the glutathione peroxidase family
ABC16_RS13105	COG0625	glutathione transferase activity
ABC16_RS13130	COG0688	phosphatidylethanolamine metabolic process
ABC16_RS13140	COG1464	Belongs to the NlpA lipoprotein family
ABC16_RS13155	COG2363	Small membrane protein
ABC16_RS13180	COG3842	ATPase activity
ABC16_RS13185	COG0395	ABC-type sugar transport system, permease component
ABC16_RS13190	COG1175	transmembrane transport
ABC16_RS13195	COG1653	transport
ABC16_RS13205	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ABC16_RS13220	COG0559	Belongs to the binding-protein-dependent transport system permease family
ABC16_RS13240	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ABC16_RS13255	COG0697	spore germination
ABC16_RS13265	COG2311	Membrane
ABC16_RS13290	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ABC16_RS13300	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ABC16_RS13305	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ABC16_RS13310	COG1760	l-serine dehydratase
ABC16_RS13315	COG1283	sodium-dependent phosphate transmembrane transporter activity
ABC16_RS13320	COG0412	Dienelactone hydrolase
ABC16_RS13335	COG1611	Belongs to the LOG family
ABC16_RS13355	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ABC16_RS13360	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ABC16_RS13365	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ABC16_RS13370	COG2251	uridine kinase activity
ABC16_RS13370	COG0195	Participates in both transcription termination and antitermination
ABC16_RS13375	COG0779	Required for maturation of 30S ribosomal subunits
ABC16_RS13380	COG1187	pseudouridine synthase activity
ABC16_RS13385	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ABC16_RS13395	COG0583	DNA-binding transcription factor activity
ABC16_RS13405	COG0523	cobalamin synthesis protein
ABC16_RS13425	COG0625	glutathione transferase activity
ABC16_RS13430	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ABC16_RS13435	COG1047	Peptidyl-prolyl cis-trans
ABC16_RS13440	COG2003	Belongs to the UPF0758 family
ABC16_RS13445	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
ABC16_RS13450	COG3483	tryptophan 2,3-dioxygenase activity
ABC16_RS13455	COG0254	rRNA binding
ABC16_RS13465	COG0534	Mate efflux family protein
ABC16_RS13485	COG2304	oxidoreductase activity
ABC16_RS13505	COG1028	Short-chain dehydrogenase reductase Sdr
ABC16_RS13510	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ABC16_RS13515	COG1562	ergosterol biosynthetic process
ABC16_RS13520	COG1562	ergosterol biosynthetic process
ABC16_RS13525	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
ABC16_RS13525	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
ABC16_RS13530	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ABC16_RS13540	COG0842	Transport permease protein
ABC16_RS13545	COG1131	(ABC) transporter
ABC16_RS13565	COG1477	protein flavinylation
ABC16_RS13580	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
ABC16_RS13595	COG5564	TIM-barrel signal transduction protein
ABC16_RS13600	COG5441	Belongs to the UPF0261 family
ABC16_RS13610	COG3468	outer membrane autotransporter barrel domain protein
ABC16_RS13615	COG3468	outer membrane autotransporter barrel domain protein
ABC16_RS13630	COG0542	response to heat
ABC16_RS13635	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ABC16_RS13650	COG0494	nUDIX hydrolase
ABC16_RS13655	COG3530	Putative quorum-sensing-regulated virulence factor
ABC16_RS13665	COG1595	DNA-templated transcription, initiation
ABC16_RS13670	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ABC16_RS13705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABC16_RS13710	COG0765	amino acid transport
ABC16_RS13715	COG0765	amino acid transport
ABC16_RS13740	COG2988	succinylglutamate desuccinylase activity
ABC16_RS13765	COG3181	Tripartite tricarboxylate transporter family receptor
ABC16_RS13770	COG2084	Dehydrogenase
ABC16_RS13785	COG1619	proteins homologs of microcin C7 resistance protein MccF
ABC16_RS13800	COG2814	Major facilitator Superfamily
ABC16_RS13810	COG0583	DNA-binding transcription factor activity
ABC16_RS13850	COG0672	)-iron permease
ABC16_RS13865	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
ABC16_RS13870	COG1028	Short-chain dehydrogenase reductase Sdr
ABC16_RS13875	COG3243	poly(R)-hydroxyalkanoic acid synthase
ABC16_RS13885	COG0564	pseudouridine synthase activity
ABC16_RS13895	COG1199	ATP-dependent helicase activity
ABC16_RS13900	COG2183	response to ionizing radiation
ABC16_RS13905	COG0180	Tryptophanyl-tRNA synthetase
ABC16_RS13930	COG3181	Tripartite tricarboxylate transporter family receptor
ABC16_RS13940	COG0583	DNA-binding transcription factor activity
ABC16_RS13945	COG1028	Short-chain dehydrogenase reductase Sdr
ABC16_RS13950	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ABC16_RS13955	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ABC16_RS13960	COG0508	dehydrogenase complex catalyzes the overall conversion of
ABC16_RS13965	COG0567	Dehydrogenase, E1 component
ABC16_RS13975	COG1522	sequence-specific DNA binding
ABC16_RS13985	COG0281	malic enzyme
ABC16_RS13985	COG0280	phosphate acetyltransferase
ABC16_RS13990	COG3539	Fimbrial protein
ABC16_RS14005	COG0613	PHP domain protein
ABC16_RS14015	COG0658	competence protein
ABC16_RS14015	COG2333	competence protein COMEC
ABC16_RS14045	COG0084	hydrolase, TatD family'
ABC16_RS14050	COG1136	(ABC) transporter
ABC16_RS14065	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ABC16_RS14075	COG1028	Short-chain dehydrogenase reductase Sdr
ABC16_RS14080	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ABC16_RS14095	COG1022	Amp-dependent synthetase and ligase
ABC16_RS14130	COG2205	protein histidine kinase activity
ABC16_RS14135	COG0745	RESPONSE REGULATOR receiver
ABC16_RS14140	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ABC16_RS14150	COG1295	ribonuclease BN
ABC16_RS14165	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ABC16_RS14195	COG1534	Rna-binding protein
ABC16_RS14200	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
ABC16_RS14205	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ABC16_RS14215	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ABC16_RS14225	COG0248	Ppx GppA phosphatase
ABC16_RS14250	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ABC16_RS14265	COG2732	(Barnase) inhibitor
ABC16_RS14275	COG0280	phosphate acetyltransferase
ABC16_RS14275	COG0281	malic enzyme
ABC16_RS14285	COG0436	Aminotransferase
ABC16_RS14290	COG0741	lytic transglycosylase activity
ABC16_RS14295	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ABC16_RS14320	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ABC16_RS14320	COG1648	precorrin-2 dehydrogenase activity
ABC16_RS14325	COG3468	outer membrane autotransporter barrel domain protein
ABC16_RS14335	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ABC16_RS14340	COG2027	D-alanyl-D-alanine carboxypeptidase
ABC16_RS14345	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ABC16_RS14350	COG0343	queuine tRNA-ribosyltransferase activity
ABC16_RS14355	COG1862	Preprotein translocase
ABC16_RS14360	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ABC16_RS14365	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ABC16_RS14380	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ABC16_RS14385	COG1702	phosphate starvation-inducible protein PhoH
ABC16_RS14390	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ABC16_RS14395	COG4535	Mg2 and Co2 transporter CorC
ABC16_RS14405	COG0667	Aldo Keto reductase
ABC16_RS14430	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
ABC16_RS14435	COG0745	RESPONSE REGULATOR receiver
ABC16_RS14440	COG2201	protein-glutamate methylesterase activity
ABC16_RS14450	COG0840	transmembrane signaling receptor activity
ABC16_RS14465	COG0745	RESPONSE REGULATOR receiver
ABC16_RS14500	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ABC16_RS14510	COG0739	heme binding
ABC16_RS14520	COG0521	Mo-molybdopterin cofactor biosynthetic process
ABC16_RS14530	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ABC16_RS14565	COG0625	glutathione transferase activity
ABC16_RS14580	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ABC16_RS14585	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ABC16_RS14590	COG0126	phosphoglycerate kinase activity
ABC16_RS14595	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ABC16_RS14600	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ABC16_RS14605	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ABC16_RS14615	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ABC16_RS14620	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ABC16_RS14625	COG0508	dehydrogenase complex catalyzes the overall conversion of
ABC16_RS14630	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ABC16_RS14640	COG4566	intracellular signal transduction
ABC16_RS14645	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ABC16_RS14650	COG0339	signal peptide processing
ABC16_RS14655	COG1999	signal sequence binding
ABC16_RS14675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ABC16_RS14685	COG1187	pseudouridine synthase activity
ABC16_RS14690	COG3161	chorismate lyase activity
ABC16_RS14695	COG2814	Major facilitator Superfamily
ABC16_RS14705	COG0667	Aldo Keto reductase
ABC16_RS14720	COG0335	large ribosomal subunit rRNA binding
ABC16_RS14750	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ABC16_RS14755	COG4208	sulfate ABC transporter
ABC16_RS14760	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ABC16_RS14775	COG0450	alkyl hydroperoxide reductase
ABC16_RS14780	COG1960	acyl-CoA dehydrogenase activity
ABC16_RS14795	COG0123	including yeast histone deacetylase and acetoin utilization protein
ABC16_RS14800	COG2951	lytic endotransglycosylase activity
ABC16_RS14815	COG1555	photosystem II stabilization
ABC16_RS14815	COG1596	polysaccharide export
ABC16_RS14820	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ABC16_RS14825	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ABC16_RS14830	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ABC16_RS14850	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ABC16_RS14855	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ABC16_RS14860	COG0287	Prephenate dehydrogenase
ABC16_RS14870	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ABC16_RS14885	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ABC16_RS14895	COG2814	Major facilitator Superfamily
ABC16_RS14920	COG0583	DNA-binding transcription factor activity
ABC16_RS14960	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ABC16_RS14975	COG0667	Aldo Keto reductase
ABC16_RS14985	COG5265	(ABC) transporter
ABC16_RS15030	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ABC16_RS15035	COG0439	Biotin carboxylase
ABC16_RS15040	COG2188	Transcriptional regulator
ABC16_RS15065	COG0511	ligase activity, forming carbon-carbon bonds
ABC16_RS15075	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ABC16_RS15095	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
ABC16_RS15115	COG0500	methyltransferase
ABC16_RS15120	COG5265	(ABC) transporter
ABC16_RS15135	COG0028	Belongs to the TPP enzyme family
ABC16_RS15140	COG0440	acetolactate synthase activity
ABC16_RS15145	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ABC16_RS15150	COG1183	phosphatidylcholine synthase activity
ABC16_RS15165	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ABC16_RS15170	COG1185	polyribonucleotide nucleotidyltransferase activity
ABC16_RS15185	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ABC16_RS15205	COG0149	triose-phosphate isomerase activity
ABC16_RS15210	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ABC16_RS15220	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ABC16_RS15230	COG3799	methylaspartate ammonia-lyase activity
ABC16_RS15265	COG0583	DNA-binding transcription factor activity
ABC16_RS15270	COG0626	cystathionine gamma-synthase activity
ABC16_RS15275	COG3608	succinylglutamate desuccinylase aspartoacylase
ABC16_RS15295	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABC16_RS15315	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
ABC16_RS15330	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ABC16_RS15335	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ABC16_RS15340	COG1733	regulation of RNA biosynthetic process
ABC16_RS15350	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ABC16_RS15355	COG0583	DNA-binding transcription factor activity
ABC16_RS15360	COG1597	lipid kinase activity
ABC16_RS15370	COG0671	phosphoesterase, PA-phosphatase related
ABC16_RS15400	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ABC16_RS15405	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABC16_RS15410	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABC16_RS15415	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABC16_RS15420	COG0649	NAD binding
ABC16_RS15425	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
ABC16_RS15435	COG1034	ATP synthesis coupled electron transport
ABC16_RS15440	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ABC16_RS15445	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABC16_RS15455	COG0713	ATP synthesis coupled electron transport
ABC16_RS15470	COG1007	ATP synthesis coupled electron transport
ABC16_RS15480	COG4774	siderophore transport
ABC16_RS15485	COG4774	siderophore transport
ABC16_RS15500	COG0028	Belongs to the TPP enzyme family
ABC16_RS15505	COG3181	Tripartite tricarboxylate transporter family receptor
ABC16_RS15510	COG0583	DNA-binding transcription factor activity
ABC16_RS15515	COG0560	Phosphoserine phosphatase
ABC16_RS15520	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ABC16_RS15525	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ABC16_RS15530	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ABC16_RS15545	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ABC16_RS15550	COG0308	aminopeptidase N
ABC16_RS15570	COG0028	Belongs to the TPP enzyme family
ABC16_RS15590	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABC16_RS15600	COG0318	PFAM AMP-dependent synthetase and ligase
ABC16_RS15610	COG1802	Transcriptional regulator
ABC16_RS15620	COG1802	Transcriptional regulator
ABC16_RS15630	COG1028	Short-chain dehydrogenase reductase Sdr
ABC16_RS15650	COG1126	abc transporter atp-binding protein
ABC16_RS15655	COG0765	amino acid transport
ABC16_RS15660	COG0765	amino acid transport
ABC16_RS15675	COG1538	Outer membrane efflux protein
ABC16_RS15680	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ABC16_RS15685	COG2274	protein secretion by the type I secretion system
ABC16_RS15690	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
ABC16_RS15700	COG2994	toxin metabolic process
ABC16_RS15715	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABC16_RS15720	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
ABC16_RS15730	COG0583	DNA-binding transcription factor activity
ABC16_RS15740	COG0142	geranyltranstransferase activity
ABC16_RS15750	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ABC16_RS15755	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ABC16_RS15760	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ABC16_RS15765	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ABC16_RS15815	COG3712	iron ion homeostasis
ABC16_RS15820	COG4774	siderophore transport
ABC16_RS15825	COG2353	YceI-like domain
ABC16_RS15840	COG0019	diaminopimelate decarboxylase activity
ABC16_RS15860	COG0747	negative chemotaxis
ABC16_RS15865	COG0601	transmembrane transport
ABC16_RS15870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABC16_RS15880	COG0154	amidase activity
ABC16_RS15885	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ABC16_RS15915	COG2154	pterin-4-alpha-carbinolamine dehydratase
ABC16_RS15925	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ABC16_RS15935	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ABC16_RS15940	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ABC16_RS15945	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ABC16_RS15950	COG1929	Belongs to the glycerate kinase type-1 family
ABC16_RS15955	COG0469	pyruvate kinase activity
ABC16_RS15960	COG0700	Nucleoside recognition
ABC16_RS15995	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
ABC16_RS16000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ABC16_RS16015	COG0823	Involved in the tonB-independent uptake of proteins
ABC16_RS16025	COG0848	biopolymer transport protein
ABC16_RS16030	COG0811	peptide transport
ABC16_RS16035	COG0824	Thioesterase
ABC16_RS16040	COG0442	prolyl-tRNA aminoacylation
ABC16_RS16045	COG0494	nUDIX hydrolase
ABC16_RS16060	COG2135	peptidase activity
ABC16_RS16130	COG1196	nuclear chromosome segregation
ABC16_RS16275	COG1464	Belongs to the NlpA lipoprotein family
ABC16_RS16305	COG4211	Belongs to the binding-protein-dependent transport system permease family
ABC16_RS16315	COG0154	amidase activity
ABC16_RS16320	COG0288	reversible hydration of carbon dioxide
ABC16_RS16335	COG0514	ATP-dependent DNA helicase (RecQ)
ABC16_RS16340	COG2255	four-way junction helicase activity
ABC16_RS16355	COG0632	four-way junction helicase activity
ABC16_RS16360	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ABC16_RS16380	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ABC16_RS16390	COG0006	proline dipeptidase activity
ABC16_RS16415	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ABC16_RS16430	COG4783	chaperone-mediated protein folding
ABC16_RS16435	COG0429	hydrolase of the alpha beta-hydrolase fold
ABC16_RS16465	COG0513	Belongs to the DEAD box helicase family
ABC16_RS16485	COG1546	Belongs to the CinA family
ABC16_RS16485	COG1058	Belongs to the CinA family
ABC16_RS16490	COG1414	Transcriptional regulator
ABC16_RS16510	COG0167	dihydroorotate dehydrogenase activity
ABC16_RS16515	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
ABC16_RS16520	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ABC16_RS16530	COG0583	DNA-binding transcription factor activity
ABC16_RS16590	COG0281	malic enzyme
ABC16_RS16590	COG0280	phosphate acetyltransferase
ABC16_RS16600	COG0601	transmembrane transport
ABC16_RS16605	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABC16_RS16610	COG4172	Belongs to the ABC transporter superfamily
ABC16_RS16640	COG0640	Transcriptional regulator
ABC16_RS16655	COG3135	benzoate transporter
ABC16_RS16660	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ABC16_RS16665	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ABC16_RS16670	COG0742	ribosomal rna small subunit methyltransferase
ABC16_RS16685	COG3639	organic phosphonate transmembrane transporter activity
ABC16_RS16690	COG3639	organic phosphonate transmembrane transporter activity
ABC16_RS16695	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
ABC16_RS16730	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ABC16_RS16735	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ABC16_RS16745	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ABC16_RS16750	COG1058	Belongs to the CinA family
ABC16_RS16750	COG1546	Belongs to the CinA family
ABC16_RS16755	COG0284	orotidine-5'-phosphate decarboxylase activity
ABC16_RS16760	COG1252	NADH dehydrogenase
ABC16_RS16775	COG3468	outer membrane autotransporter barrel domain protein
ABC16_RS16780	COG0459	protein refolding
ABC16_RS16785	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ABC16_RS16805	COG1053	succinate dehydrogenase
ABC16_RS16815	COG0583	DNA-binding transcription factor activity
ABC16_RS16820	COG1053	succinate dehydrogenase
ABC16_RS16840	COG3706	GGDEF domain
ABC16_RS16875	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ABC16_RS16880	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
ABC16_RS16890	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ABC16_RS16900	COG0069	glutamate synthase activity
ABC16_RS16905	COG2391	methyltransferase activity
ABC16_RS16910	COG0679	Auxin Efflux Carrier
ABC16_RS16935	COG0557	exoribonuclease II activity
ABC16_RS16940	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ABC16_RS16950	COG3128	pkhd-type hydroxylase
ABC16_RS16955	COG0776	regulation of translation
ABC16_RS16985	COG0642	Histidine kinase
ABC16_RS16990	COG3158	transport of potassium into the cell
ABC16_RS16995	COG0137	argininosuccinate synthase activity
ABC16_RS17000	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ABC16_RS17005	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ABC16_RS17015	COG0583	DNA-binding transcription factor activity
ABC16_RS17025	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ABC16_RS17045	COG2186	Transcriptional regulator
ABC16_RS17055	COG2223	nitrite transmembrane transporter activity
ABC16_RS17065	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ABC16_RS17070	COG0450	alkyl hydroperoxide reductase
ABC16_RS17090	COG1214	PFAM Peptidase M22, glycoprotease
ABC16_RS17095	COG1573	uracil-dna glycosylase
ABC16_RS17100	COG0477	Major facilitator Superfamily
ABC16_RS17105	COG1196	nuclear chromosome segregation
ABC16_RS17115	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ABC16_RS17120	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ABC16_RS17135	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ABC16_RS17140	COG1122	ATPase activity
ABC16_RS17145	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ABC16_RS17150	COG1268	BioY protein
ABC16_RS17170	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ABC16_RS17205	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ABC16_RS17210	COG2878	Part of a membrane complex involved in electron transport
ABC16_RS17225	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ABC16_RS17230	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ABC16_RS17235	COG0251	oxidation-reduction process
ABC16_RS17245	COG3228	Belongs to the MtfA family
ABC16_RS17250	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ABC16_RS17260	COG0133	tryptophan synthase activity
ABC16_RS17265	COG0159	tryptophan synthase activity
ABC16_RS17270	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ABC16_RS17275	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
ABC16_RS17290	COG1530	ribonuclease E activity
ABC16_RS17300	COG0546	phosphoglycolate phosphatase activity
ABC16_RS17305	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ABC16_RS17310	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
ABC16_RS17320	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC16_RS17325	COG0583	DNA-binding transcription factor activity
ABC16_RS17335	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC16_RS17355	COG0251	oxidation-reduction process
ABC16_RS17360	COG1017	nitric oxide dioxygenase activity
ABC16_RS17360	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ABC16_RS17365	COG2031	fatty acid transporter
ABC16_RS17370	COG1012	belongs to the aldehyde dehydrogenase family
ABC16_RS17375	COG1802	Transcriptional regulator
ABC16_RS17385	COG1278	Cold shock
ABC16_RS17390	COG0583	DNA-binding transcription factor activity
ABC16_RS17410	COG0183	Belongs to the thiolase family
ABC16_RS17420	COG1960	acyl-CoA dehydrogenase activity
ABC16_RS17425	COG0583	DNA-binding transcription factor activity
ABC16_RS17430	COG3181	Tripartite tricarboxylate transporter family receptor
ABC16_RS17435	COG1024	Enoyl-CoA hydratase
ABC16_RS17440	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC16_RS17445	COG1253	flavin adenine dinucleotide binding
ABC16_RS17450	COG1285	pathogenesis
ABC16_RS17460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ABC16_RS17475	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ABC16_RS17485	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ABC16_RS17495	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC16_RS17500	COG3181	Tripartite tricarboxylate transporter family receptor
ABC16_RS17505	COG1960	acyl-CoA dehydrogenase activity
ABC16_RS17525	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ABC16_RS17530	COG1024	Enoyl-CoA hydratase
ABC16_RS17535	COG1960	acyl-CoA dehydrogenase activity
ABC16_RS17555	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ABC16_RS17560	COG0022	dehydrogenase e1 component
ABC16_RS17565	COG1024	Enoyl-CoA hydratase
ABC16_RS17570	COG0508	dehydrogenase complex catalyzes the overall conversion of
ABC16_RS17590	COG0683	leucine binding
ABC16_RS17595	COG0559	Belongs to the binding-protein-dependent transport system permease family
ABC16_RS17600	COG0411	ABC transporter
ABC16_RS17610	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ABC16_RS17625	COG3181	Tripartite tricarboxylate transporter family receptor
ABC16_RS17655	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ABC16_RS17660	COG0793	Belongs to the peptidase S41A family
ABC16_RS17665	COG4942	peptidase
ABC16_RS17670	COG0588	phosphoglycerate mutase activity
ABC16_RS17675	COG1054	Belongs to the UPF0176 family
ABC16_RS17680	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ABC16_RS17685	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
ABC16_RS17690	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ABC16_RS17695	COG3181	Tripartite tricarboxylate transporter family receptor
ABC16_RS17710	COG2226	methyltransferase
ABC16_RS17715	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ABC16_RS17730	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABC16_RS17735	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ABC16_RS17760	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ABC16_RS17785	COG1335	isochorismatase
ABC16_RS17790	COG2309	aminopeptidase activity
ABC16_RS17795	COG0596	Alpha beta hydrolase
ABC16_RS17800	COG3473	Maleate cis-trans isomerase
ABC16_RS17810	COG2068	MobA-Related Protein
ABC16_RS17835	COG2204	response regulator
ABC16_RS17840	COG5000	phosphorelay sensor kinase activity
ABC16_RS17850	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ABC16_RS17850	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ABC16_RS17860	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
ABC16_RS17890	COG0583	DNA-binding transcription factor activity
ABC16_RS17905	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ABC16_RS17910	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ABC16_RS17915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABC16_RS17930	COG0758	DNA mediated transformation
ABC16_RS17935	COG1522	sequence-specific DNA binding
ABC16_RS17945	COG0242	peptide deformylase activity
ABC16_RS17960	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ABC16_RS17970	COG0546	phosphoglycolate phosphatase activity
ABC16_RS17990	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ABC16_RS17995	COG1942	4-Oxalocrotonate Tautomerase
ABC16_RS18000	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABC16_RS18025	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ABC16_RS18045	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ABC16_RS18050	COG1024	Enoyl-CoA hydratase
ABC16_RS18055	COG1414	Transcriptional regulator
ABC16_RS18060	COG0318	PFAM AMP-dependent synthetase and ligase
ABC16_RS18065	COG3181	Tripartite tricarboxylate transporter family receptor
ABC16_RS18095	COG0583	DNA-binding transcription factor activity
ABC16_RS18110	COG3422	double-strand break repair
ABC16_RS18115	COG0330	HflC and HflK could
ABC16_RS18125	COG0251	oxidation-reduction process
ABC16_RS18170	COG3723	Recombinational DNA repair protein, rece pathway
ABC16_RS18205	COG0582	viral genome integration into host DNA
ABC16_RS18230	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ABC16_RS18240	COG0706	membrane insertase activity
ABC16_RS18245	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ABC16_RS18250	COG0594	ribonuclease P activity
ABC16_RS18255	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ABC16_RS18260	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ABC16_RS18275	COG1414	Transcriptional regulator
ABC16_RS18280	COG0154	amidase activity
ABC16_RS18295	COG1304	FMN binding
ABC16_RS18315	COG1960	acyl-CoA dehydrogenase activity
ABC16_RS18335	COG1960	acyl-CoA dehydrogenase activity
ABC16_RS18350	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ABC16_RS18365	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ABC16_RS18370	COG3181	Tripartite tricarboxylate transporter family receptor
ABC16_RS18380	COG2358	TRAP transporter, solute receptor (TAXI family
ABC16_RS18390	COG1629	transport
ABC16_RS18395	COG2922	Belongs to the Smg family
ABC16_RS18420	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ABC16_RS18425	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABC16_RS18430	COG1028	Short-chain dehydrogenase reductase Sdr
ABC16_RS18435	COG1012	belongs to the aldehyde dehydrogenase family
ABC16_RS18445	COG0028	Belongs to the TPP enzyme family
ABC16_RS18450	COG1522	sequence-specific DNA binding
ABC16_RS18455	COG3781	membrane
ABC16_RS18465	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ABC16_RS18485	COG4206	TonB-dependent receptor
ABC16_RS18490	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ABC16_RS18495	COG2022	thiamine diphosphate biosynthetic process
ABC16_RS18500	COG0351	phosphomethylpyrimidine kinase
ABC16_RS18505	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ABC16_RS18520	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ABC16_RS18530	COG0628	permease
ABC16_RS18540	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ABC16_RS18550	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ABC16_RS18555	COG0049	tRNA binding
ABC16_RS18560	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ABC16_RS18565	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ABC16_RS18570	COG0051	transcription antitermination factor activity, RNA binding
ABC16_RS18575	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ABC16_RS18580	COG0088	Forms part of the polypeptide exit tunnel
ABC16_RS18585	COG0089	rRNA binding
ABC16_RS18590	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ABC16_RS18595	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ABC16_RS18600	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ABC16_RS18605	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ABC16_RS18610	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ABC16_RS18615	COG0255	Belongs to the universal ribosomal protein uL29 family
ABC16_RS18620	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ABC16_RS18640	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ABC16_RS18645	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ABC16_RS18650	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ABC16_RS18655	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ABC16_RS18660	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ABC16_RS18665	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ABC16_RS18670	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ABC16_RS18675	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ABC16_RS18680	COG1841	ribosomal large subunit assembly
ABC16_RS18685	COG0200	Binds to the 23S rRNA
ABC16_RS18690	COG0201	protein transport
ABC16_RS18695	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ABC16_RS18700	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ABC16_RS18705	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ABC16_RS18710	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ABC16_RS18715	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ABC16_RS18720	COG0202	RNA polymerase activity
ABC16_RS18725	COG0203	ribosomal protein L17
ABC16_RS18730	COG0537	adenosine 5'-monophosphoramidase activity
ABC16_RS18735	COG1324	tolerance protein
ABC16_RS18740	COG4232	protein-disulfide reductase activity
ABC16_RS18755	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ABC16_RS18765	COG1333	cytochrome c biogenesis protein
ABC16_RS18770	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ABC16_RS18785	COG1965	Belongs to the frataxin family
ABC16_RS18795	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ABC16_RS18800	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ABC16_RS18805	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ABC16_RS18820	COG2814	Major facilitator Superfamily
ABC16_RS18825	COG0629	single-stranded DNA binding
ABC16_RS18865	COG0402	S-adenosylhomocysteine deaminase activity
ABC16_RS18875	COG0438	transferase activity, transferring glycosyl groups
ABC16_RS18895	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABC16_RS18920	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ABC16_RS18925	COG2186	Transcriptional regulator
ABC16_RS18945	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ABC16_RS18950	COG1956	GAF domain-containing protein
ABC16_RS18955	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ABC16_RS18970	COG1652	LysM domain
ABC16_RS18985	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ABC16_RS19000	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ABC16_RS19030	COG3181	Tripartite tricarboxylate transporter family receptor
ABC16_RS19045	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABC16_RS19060	COG1024	Enoyl-CoA hydratase
ABC16_RS19075	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC16_RS19080	COG1309	transcriptional regulator
ABC16_RS19085	COG2816	NAD+ diphosphatase activity
ABC16_RS19090	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ABC16_RS19175	COG2814	Major facilitator Superfamily
ABC16_RS19180	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ABC16_RS19200	COG1999	signal sequence binding
ABC16_RS19205	COG0109	protoheme IX farnesyltransferase activity
ABC16_RS19245	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ABC16_RS19265	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ABC16_RS19270	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ABC16_RS19280	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
ABC16_RS19285	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
ABC16_RS19295	COG0069	glutamate synthase activity
ABC16_RS19295	COG0070	glutamate synthase
ABC16_RS19295	COG0067	glutamate synthase
ABC16_RS19305	COG3047	cAMP biosynthetic process
ABC16_RS19315	COG1127	ABC transporter
ABC16_RS19320	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ABC16_RS19325	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ABC16_RS19330	COG2853	Lipoprotein
ABC16_RS19340	COG1131	(ABC) transporter
ABC16_RS19345	COG0842	Transport permease protein
ABC16_RS19355	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ABC16_RS19360	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ABC16_RS19365	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ABC16_RS19370	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ABC16_RS19375	COG0131	Imidazoleglycerol-phosphate dehydratase
ABC16_RS19380	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ABC16_RS19385	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ABC16_RS19390	COG0107	imidazoleglycerol-phosphate synthase activity
ABC16_RS19395	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ABC16_RS19400	COG0140	phosphoribosyl-ATP diphosphatase activity
ABC16_RS19405	COG0537	adenosine 5'-monophosphoramidase activity
ABC16_RS19410	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ABC16_RS19415	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ABC16_RS19430	COG3181	Tripartite tricarboxylate transporter family receptor
ABC16_RS19465	COG3702	type iv secretory pathway
ABC16_RS19470	COG3451	type IV secretory pathway VirB4
ABC16_RS19485	COG3736	Type IV secretory pathway, component VirB8
ABC16_RS19490	COG3504	Conjugal transfer protein
ABC16_RS19495	COG2948	multi-organism process
ABC16_RS19500	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
ABC16_RS19510	COG0697	spore germination
ABC16_RS19530	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ABC16_RS19535	COG0747	negative chemotaxis
ABC16_RS19540	COG0601	transmembrane transport
ABC16_RS19545	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABC16_RS19550	COG0444	Belongs to the ABC transporter superfamily
ABC16_RS19560	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ABC16_RS19570	COG0494	nUDIX hydrolase
ABC16_RS19610	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
ABC16_RS19615	COG0237	dephospho-CoA kinase activity
ABC16_RS19620	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ABC16_RS19635	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ABC16_RS19640	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ABC16_RS19650	COG0477	Major facilitator Superfamily
ABC16_RS19655	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ABC16_RS19670	COG1126	abc transporter atp-binding protein
ABC16_RS19675	COG0765	amino acid transport
ABC16_RS19680	COG4597	amino acid ABC transporter
ABC16_RS19685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABC16_RS19690	COG2884	Cell division ATP-binding protein ftsE
ABC16_RS19695	COG2177	Part of the ABC transporter FtsEX involved in
ABC16_RS19700	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ABC16_RS19710	COG1194	a g-specific adenine glycosylase
ABC16_RS19720	COG2226	methyltransferase
ABC16_RS19730	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC16_RS19735	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC16_RS19750	COG1024	Enoyl-CoA hydratase
ABC16_RS19770	COG1024	Enoyl-CoA hydratase
ABC16_RS19775	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC16_RS19780	COG3181	Tripartite tricarboxylate transporter family receptor
ABC16_RS19790	COG0753	catalase activity
ABC16_RS19795	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABC16_RS19800	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ABC16_RS19810	COG2175	clavaminate synthase activity
ABC16_RS19815	COG1473	amidohydrolase
ABC16_RS19820	COG4608	Belongs to the ABC transporter superfamily
ABC16_RS19825	COG0444	Belongs to the ABC transporter superfamily
ABC16_RS19840	COG0747	negative chemotaxis
ABC16_RS19845	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ABC16_RS19880	COG0436	Aminotransferase
ABC16_RS19885	COG1278	Cold shock