locus-tag	class	description
ADU64_RS00005	COG0445	tRNA wobble uridine modification
ADU64_RS00010	COG0357	Ribosomal RNA small subunit methyltransferase G
ADU64_RS00015	COG1192	Involved in chromosome partitioning
ADU64_RS00025	COG1475	DNA binding
ADU64_RS00030	COG0252	asparaginase activity
ADU64_RS00055	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ADU64_RS00065	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ADU64_RS00075	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ADU64_RS00080	COG0081	regulation of translation
ADU64_RS00085	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ADU64_RS00090	COG0222	ribosome binding
ADU64_RS00095	COG0085	RNA polymerase activity
ADU64_RS00100	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ADU64_RS00140	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ADU64_RS00165	COG1024	Enoyl-CoA hydratase
ADU64_RS00185	COG0752	glycyl-tRNA synthetase alpha subunit
ADU64_RS00190	COG0751	glycine-tRNA ligase activity
ADU64_RS00195	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ADU64_RS00200	COG0204	Acyl-transferase
ADU64_RS00215	COG0242	peptide deformylase activity
ADU64_RS00250	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ADU64_RS00255	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ADU64_RS00260	COG2813	Specifically methylates the guanine in position
ADU64_RS00260	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ADU64_RS00275	COG2223	nitrite transmembrane transporter activity
ADU64_RS00285	COG1794	racemase activity, acting on amino acids and derivatives
ADU64_RS00290	COG1126	abc transporter atp-binding protein
ADU64_RS00295	COG0765	amino acid transport
ADU64_RS00300	COG0765	amino acid transport
ADU64_RS00305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ADU64_RS00370	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ADU64_RS00400	COG0326	Molecular chaperone. Has ATPase activity
ADU64_RS00405	COG0625	glutathione transferase activity
ADU64_RS00420	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ADU64_RS00425	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ADU64_RS00455	COG0438	transferase activity, transferring glycosyl groups
ADU64_RS00460	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ADU64_RS00465	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ADU64_RS00495	COG0859	PFAM glycosyl transferase family 9
ADU64_RS00510	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ADU64_RS00520	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ADU64_RS00525	COG1127	ABC transporter
ADU64_RS00545	COG1686	Belongs to the peptidase S11 family
ADU64_RS00555	COG2921	Belongs to the UPF0250 family
ADU64_RS00560	COG0321	lipoyl(octanoyl) transferase activity
ADU64_RS00565	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ADU64_RS00600	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ADU64_RS00610	COG0018	arginyl-trna synthetase
ADU64_RS00630	COG0395	ABC-type sugar transport system, permease component
ADU64_RS00635	COG1175	transmembrane transport
ADU64_RS00640	COG1653	transport
ADU64_RS00645	COG3842	ATPase activity
ADU64_RS00650	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ADU64_RS00660	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ADU64_RS00680	COG1609	Transcriptional regulator
ADU64_RS00690	COG0154	amidase activity
ADU64_RS00695	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ADU64_RS00705	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ADU64_RS00715	COG0583	DNA-binding transcription factor activity
ADU64_RS00730	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ADU64_RS00735	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ADU64_RS00750	COG1802	Transcriptional regulator
ADU64_RS00765	COG1024	Enoyl-CoA hydratase
ADU64_RS00775	COG3181	Tripartite tricarboxylate transporter family receptor
ADU64_RS00790	COG1984	allophanate hydrolase subunit 2
ADU64_RS00795	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ADU64_RS00805	COG0583	DNA-binding transcription factor activity
ADU64_RS00810	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ADU64_RS00820	COG5002	protein histidine kinase activity
ADU64_RS00830	COG5002	protein histidine kinase activity
ADU64_RS00835	COG0745	RESPONSE REGULATOR receiver
ADU64_RS00840	COG2226	methyltransferase
ADU64_RS00855	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ADU64_RS00875	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
ADU64_RS00885	COG0513	Belongs to the DEAD box helicase family
ADU64_RS00890	COG1280	lysine exporter protein (LysE YggA)
ADU64_RS00895	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ADU64_RS00930	COG1054	Belongs to the UPF0176 family
ADU64_RS00935	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ADU64_RS00935	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ADU64_RS00945	COG0489	protein tyrosine kinase activity
ADU64_RS00960	COG0717	Belongs to the dCTP deaminase family
ADU64_RS00990	COG2081	HI0933 family
ADU64_RS01000	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ADU64_RS01010	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ADU64_RS01015	COG0509	glycine decarboxylation via glycine cleavage system
ADU64_RS01020	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ADU64_RS01020	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ADU64_RS01060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ADU64_RS01075	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ADU64_RS01085	COG1414	Transcriptional regulator
ADU64_RS01090	COG1028	Short-chain dehydrogenase reductase Sdr
ADU64_RS01095	COG2031	fatty acid transporter
ADU64_RS01100	COG1250	3-hydroxyacyl-CoA dehydrogenase
ADU64_RS01110	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ADU64_RS01115	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ADU64_RS01125	COG4257	antibiotic catabolic process
ADU64_RS01150	COG1012	belongs to the aldehyde dehydrogenase family
ADU64_RS01155	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ADU64_RS01160	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ADU64_RS01185	COG1028	Short-chain dehydrogenase reductase Sdr
ADU64_RS01195	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ADU64_RS01210	COG2188	Transcriptional regulator
ADU64_RS01215	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ADU64_RS01240	COG0617	tRNA 3'-terminal CCA addition
ADU64_RS01255	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ADU64_RS01260	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ADU64_RS01265	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ADU64_RS01270	COG0586	Pfam SNARE associated Golgi protein
ADU64_RS01275	COG0860	N-Acetylmuramoyl-L-alanine amidase
ADU64_RS01280	COG0802	atpase or kinase
ADU64_RS01285	COG0114	fumarate hydratase activity
ADU64_RS01295	COG3181	Tripartite tricarboxylate transporter family receptor
ADU64_RS01305	COG0405	Gamma-glutamyltransferase
ADU64_RS01310	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ADU64_RS01320	COG1960	acyl-CoA dehydrogenase activity
ADU64_RS01345	COG1294	oxidase, subunit
ADU64_RS01355	COG4988	ABC transporter
ADU64_RS01360	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ADU64_RS01365	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ADU64_RS01380	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ADU64_RS01410	COG2969	positive regulation of protein catabolic process
ADU64_RS01415	COG0625	glutathione transferase activity
ADU64_RS01420	COG2857	Cytochrome c1
ADU64_RS01425	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ADU64_RS01430	COG0723	plastoquinol--plastocyanin reductase activity
ADU64_RS01435	COG1970	mechanosensitive ion channel activity
ADU64_RS01440	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ADU64_RS01455	COG2808	Putative FMN-binding domain
ADU64_RS01460	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ADU64_RS01465	COG0747	negative chemotaxis
ADU64_RS01470	COG0657	acetylesterase activity
ADU64_RS01480	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ADU64_RS01485	COG2207	Transcriptional regulator
ADU64_RS01490	COG0129	dihydroxy-acid dehydratase activity
ADU64_RS01495	COG2814	Major facilitator Superfamily
ADU64_RS01500	COG0583	DNA-binding transcription factor activity
ADU64_RS01510	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
ADU64_RS01580	COG1024	Enoyl-CoA hydratase
ADU64_RS01585	COG1960	acyl-CoA dehydrogenase activity
ADU64_RS01610	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ADU64_RS01615	COG0352	thiamine-phosphate diphosphorylase activity
ADU64_RS01630	COG1678	Uncharacterized ACR, COG1678
ADU64_RS01635	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ADU64_RS01640	COG0540	Belongs to the ATCase OTCase family
ADU64_RS01655	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ADU64_RS01665	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ADU64_RS01700	COG1234	tRNA 3'-trailer cleavage
ADU64_RS01720	COG3064	Membrane
ADU64_RS01750	COG1683	Conserved Protein
ADU64_RS01755	COG1120	ATPase activity
ADU64_RS01760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ADU64_RS01765	COG4558	Periplasmic binding protein
ADU64_RS01770	COG3720	iron ion transport
ADU64_RS01780	COG3712	iron ion homeostasis
ADU64_RS01785	COG1595	DNA-templated transcription, initiation
ADU64_RS01820	COG1802	Transcriptional regulator
ADU64_RS01830	COG3069	C4-dicarboxylate transmembrane transporter activity
ADU64_RS01840	COG1012	belongs to the aldehyde dehydrogenase family
ADU64_RS01875	COG2860	membrane
ADU64_RS01880	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ADU64_RS01885	COG0708	Exodeoxyribonuclease III
ADU64_RS01890	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ADU64_RS01895	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ADU64_RS01900	COG0154	amidase activity
ADU64_RS01905	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ADU64_RS01910	COG1077	Cell shape determining protein MreB Mrl
ADU64_RS01915	COG1792	Involved in formation and maintenance of cell shape
ADU64_RS01925	COG0768	penicillin binding
ADU64_RS01930	COG0772	Belongs to the SEDS family
ADU64_RS01935	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ADU64_RS01940	COG0471	metal ion transport
ADU64_RS01945	COG1309	transcriptional regulator
ADU64_RS01955	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ADU64_RS01970	COG2823	Periplasmic or secreted lipoprotein
ADU64_RS01975	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ADU64_RS01990	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ADU64_RS02010	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ADU64_RS02020	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ADU64_RS02040	COG0492	ferredoxin-NADP+ reductase activity
ADU64_RS02050	COG3181	Tripartite tricarboxylate transporter family receptor
ADU64_RS02055	COG1024	Enoyl-CoA hydratase
ADU64_RS02055	COG1250	3-hydroxyacyl-CoA dehydrogenase
ADU64_RS02060	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ADU64_RS02065	COG0028	Belongs to the TPP enzyme family
ADU64_RS02090	COG3181	Tripartite tricarboxylate transporter family receptor
ADU64_RS02100	COG0697	spore germination
ADU64_RS02130	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ADU64_RS02135	COG0463	Glycosyl transferase, family 2
ADU64_RS02155	COG0786	glutamate:sodium symporter activity
ADU64_RS02165	COG2031	fatty acid transporter
ADU64_RS02180	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ADU64_RS02185	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ADU64_RS02195	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ADU64_RS02210	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ADU64_RS02220	COG1285	pathogenesis
ADU64_RS02225	COG1253	flavin adenine dinucleotide binding
ADU64_RS02230	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ADU64_RS02235	COG1024	Enoyl-CoA hydratase
ADU64_RS02240	COG3181	Tripartite tricarboxylate transporter family receptor
ADU64_RS02245	COG0583	DNA-binding transcription factor activity
ADU64_RS02250	COG1960	acyl-CoA dehydrogenase activity
ADU64_RS02260	COG0183	Belongs to the thiolase family
ADU64_RS02280	COG0583	DNA-binding transcription factor activity
ADU64_RS02285	COG1278	Cold shock
ADU64_RS02295	COG1802	Transcriptional regulator
ADU64_RS02300	COG1012	belongs to the aldehyde dehydrogenase family
ADU64_RS02305	COG2031	fatty acid transporter
ADU64_RS02310	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ADU64_RS02310	COG1017	nitric oxide dioxygenase activity
ADU64_RS02315	COG0251	oxidation-reduction process
ADU64_RS02335	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ADU64_RS02345	COG0583	DNA-binding transcription factor activity
ADU64_RS02350	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ADU64_RS02360	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
ADU64_RS02365	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ADU64_RS02370	COG0546	phosphoglycolate phosphatase activity
ADU64_RS02380	COG1530	ribonuclease E activity
ADU64_RS02395	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
ADU64_RS02400	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ADU64_RS02405	COG0159	tryptophan synthase activity
ADU64_RS02410	COG0133	tryptophan synthase activity
ADU64_RS02420	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ADU64_RS02425	COG3228	Belongs to the MtfA family
ADU64_RS02435	COG0251	oxidation-reduction process
ADU64_RS02440	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ADU64_RS02445	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ADU64_RS02460	COG2878	Part of a membrane complex involved in electron transport
ADU64_RS02465	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ADU64_RS02500	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ADU64_RS02520	COG1268	BioY protein
ADU64_RS02525	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ADU64_RS02530	COG1122	ATPase activity
ADU64_RS02535	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ADU64_RS02550	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ADU64_RS02555	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ADU64_RS02565	COG1196	nuclear chromosome segregation
ADU64_RS02570	COG0477	Major facilitator Superfamily
ADU64_RS02575	COG1573	uracil-dna glycosylase
ADU64_RS02580	COG1214	PFAM Peptidase M22, glycoprotease
ADU64_RS02605	COG0450	alkyl hydroperoxide reductase
ADU64_RS02610	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ADU64_RS02620	COG2223	nitrite transmembrane transporter activity
ADU64_RS02630	COG2186	Transcriptional regulator
ADU64_RS02650	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ADU64_RS02660	COG0583	DNA-binding transcription factor activity
ADU64_RS02670	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ADU64_RS02675	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ADU64_RS02680	COG0137	argininosuccinate synthase activity
ADU64_RS02685	COG3158	transport of potassium into the cell
ADU64_RS02690	COG0642	Histidine kinase
ADU64_RS02720	COG0776	regulation of translation
ADU64_RS02725	COG3128	pkhd-type hydroxylase
ADU64_RS02735	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ADU64_RS02740	COG0557	exoribonuclease II activity
ADU64_RS02765	COG0679	Auxin Efflux Carrier
ADU64_RS02770	COG2391	methyltransferase activity
ADU64_RS02775	COG0069	glutamate synthase activity
ADU64_RS02785	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ADU64_RS02795	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
ADU64_RS02800	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ADU64_RS02835	COG3706	GGDEF domain
ADU64_RS02850	COG1053	succinate dehydrogenase
ADU64_RS02855	COG0583	DNA-binding transcription factor activity
ADU64_RS02865	COG1053	succinate dehydrogenase
ADU64_RS02885	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ADU64_RS02890	COG0459	protein refolding
ADU64_RS02895	COG3468	outer membrane autotransporter barrel domain protein
ADU64_RS02910	COG1252	NADH dehydrogenase
ADU64_RS02915	COG0284	orotidine-5'-phosphate decarboxylase activity
ADU64_RS02920	COG1546	Belongs to the CinA family
ADU64_RS02920	COG1058	Belongs to the CinA family
ADU64_RS02925	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ADU64_RS02935	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ADU64_RS02940	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ADU64_RS02975	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
ADU64_RS02980	COG3639	organic phosphonate transmembrane transporter activity
ADU64_RS02985	COG3639	organic phosphonate transmembrane transporter activity
ADU64_RS03005	COG0742	ribosomal rna small subunit methyltransferase
ADU64_RS03010	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ADU64_RS03015	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ADU64_RS03020	COG3135	benzoate transporter
ADU64_RS03035	COG0640	Transcriptional regulator
ADU64_RS03065	COG4172	Belongs to the ABC transporter superfamily
ADU64_RS03070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ADU64_RS03075	COG0601	transmembrane transport
ADU64_RS03085	COG0281	malic enzyme
ADU64_RS03085	COG0280	phosphate acetyltransferase
ADU64_RS03145	COG0583	DNA-binding transcription factor activity
ADU64_RS03155	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ADU64_RS03160	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
ADU64_RS03165	COG0167	dihydroorotate dehydrogenase activity
ADU64_RS03185	COG1414	Transcriptional regulator
ADU64_RS03190	COG1058	Belongs to the CinA family
ADU64_RS03190	COG1546	Belongs to the CinA family
ADU64_RS03210	COG0513	Belongs to the DEAD box helicase family
ADU64_RS03240	COG0429	hydrolase of the alpha beta-hydrolase fold
ADU64_RS03245	COG4783	chaperone-mediated protein folding
ADU64_RS03260	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ADU64_RS03285	COG0006	proline dipeptidase activity
ADU64_RS03295	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ADU64_RS03315	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ADU64_RS03320	COG0632	four-way junction helicase activity
ADU64_RS03335	COG2255	four-way junction helicase activity
ADU64_RS03340	COG0514	ATP-dependent DNA helicase (RecQ)
ADU64_RS03355	COG0288	reversible hydration of carbon dioxide
ADU64_RS03360	COG0154	amidase activity
ADU64_RS03370	COG4211	Belongs to the binding-protein-dependent transport system permease family
ADU64_RS03400	COG1464	Belongs to the NlpA lipoprotein family
ADU64_RS03545	COG1196	nuclear chromosome segregation
ADU64_RS03615	COG2135	peptidase activity
ADU64_RS03630	COG0494	nUDIX hydrolase
ADU64_RS03635	COG0442	prolyl-tRNA aminoacylation
ADU64_RS03640	COG0824	Thioesterase
ADU64_RS03645	COG0811	peptide transport
ADU64_RS03650	COG0848	biopolymer transport protein
ADU64_RS03660	COG0823	Involved in the tonB-independent uptake of proteins
ADU64_RS03675	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ADU64_RS03680	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
ADU64_RS03715	COG0700	Nucleoside recognition
ADU64_RS03720	COG0469	pyruvate kinase activity
ADU64_RS03725	COG1929	Belongs to the glycerate kinase type-1 family
ADU64_RS03730	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ADU64_RS03735	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ADU64_RS03740	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ADU64_RS03750	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ADU64_RS03760	COG2154	pterin-4-alpha-carbinolamine dehydratase
ADU64_RS03785	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ADU64_RS03790	COG0154	amidase activity
ADU64_RS03800	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ADU64_RS03805	COG0601	transmembrane transport
ADU64_RS03810	COG0747	negative chemotaxis
ADU64_RS03830	COG0019	diaminopimelate decarboxylase activity
ADU64_RS03845	COG2353	YceI-like domain
ADU64_RS03850	COG4774	siderophore transport
ADU64_RS03855	COG3712	iron ion homeostasis
ADU64_RS03895	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ADU64_RS03900	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ADU64_RS03905	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ADU64_RS03910	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ADU64_RS03920	COG0142	geranyltranstransferase activity
ADU64_RS03930	COG0583	DNA-binding transcription factor activity
ADU64_RS03940	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
ADU64_RS03945	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ADU64_RS03960	COG2994	toxin metabolic process
ADU64_RS03970	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
ADU64_RS03975	COG2274	protein secretion by the type I secretion system
ADU64_RS03980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ADU64_RS03985	COG1538	Outer membrane efflux protein
ADU64_RS04000	COG0765	amino acid transport
ADU64_RS04005	COG0765	amino acid transport
ADU64_RS04010	COG1126	abc transporter atp-binding protein
ADU64_RS04030	COG1028	Short-chain dehydrogenase reductase Sdr
ADU64_RS04040	COG1802	Transcriptional regulator
ADU64_RS04050	COG1802	Transcriptional regulator
ADU64_RS04060	COG0318	PFAM AMP-dependent synthetase and ligase
ADU64_RS04070	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ADU64_RS04090	COG0028	Belongs to the TPP enzyme family
ADU64_RS04110	COG0308	aminopeptidase N
ADU64_RS04115	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ADU64_RS04125	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ADU64_RS04130	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ADU64_RS04135	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ADU64_RS04140	COG0560	Phosphoserine phosphatase
ADU64_RS04145	COG0583	DNA-binding transcription factor activity
ADU64_RS04150	COG3181	Tripartite tricarboxylate transporter family receptor
ADU64_RS04155	COG0028	Belongs to the TPP enzyme family
ADU64_RS04170	COG4774	siderophore transport
ADU64_RS04175	COG4774	siderophore transport
ADU64_RS04185	COG1007	ATP synthesis coupled electron transport
ADU64_RS04200	COG0713	ATP synthesis coupled electron transport
ADU64_RS04210	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ADU64_RS04215	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ADU64_RS04220	COG1034	ATP synthesis coupled electron transport
ADU64_RS04230	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
ADU64_RS04235	COG0649	NAD binding
ADU64_RS04240	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ADU64_RS04245	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ADU64_RS04250	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ADU64_RS04255	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ADU64_RS04285	COG0671	phosphoesterase, PA-phosphatase related
ADU64_RS04295	COG1597	lipid kinase activity
ADU64_RS04300	COG0583	DNA-binding transcription factor activity
ADU64_RS04305	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ADU64_RS04315	COG1733	regulation of RNA biosynthetic process
ADU64_RS04320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ADU64_RS04325	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ADU64_RS04340	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
ADU64_RS04360	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ADU64_RS04380	COG3608	succinylglutamate desuccinylase aspartoacylase
ADU64_RS04385	COG0626	cystathionine gamma-synthase activity
ADU64_RS04390	COG0583	DNA-binding transcription factor activity
ADU64_RS04425	COG3799	methylaspartate ammonia-lyase activity
ADU64_RS04435	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ADU64_RS04445	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ADU64_RS04450	COG0149	triose-phosphate isomerase activity
ADU64_RS04470	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ADU64_RS04485	COG1185	polyribonucleotide nucleotidyltransferase activity
ADU64_RS04490	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ADU64_RS04505	COG1183	phosphatidylcholine synthase activity
ADU64_RS04510	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ADU64_RS04515	COG0440	acetolactate synthase activity
ADU64_RS04520	COG0028	Belongs to the TPP enzyme family
ADU64_RS04535	COG5265	(ABC) transporter
ADU64_RS04540	COG0500	methyltransferase
ADU64_RS04560	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
ADU64_RS04580	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ADU64_RS04590	COG0511	ligase activity, forming carbon-carbon bonds
ADU64_RS04615	COG2188	Transcriptional regulator
ADU64_RS04620	COG0439	Biotin carboxylase
ADU64_RS04625	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ADU64_RS04670	COG5265	(ABC) transporter
ADU64_RS04680	COG0667	Aldo Keto reductase
ADU64_RS04695	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ADU64_RS04735	COG0583	DNA-binding transcription factor activity
ADU64_RS04760	COG2814	Major facilitator Superfamily
ADU64_RS04770	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ADU64_RS04785	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ADU64_RS04795	COG0287	Prephenate dehydrogenase
ADU64_RS04800	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ADU64_RS04805	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ADU64_RS04825	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ADU64_RS04830	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ADU64_RS04835	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ADU64_RS04840	COG1555	photosystem II stabilization
ADU64_RS04840	COG1596	polysaccharide export
ADU64_RS04855	COG2951	lytic endotransglycosylase activity
ADU64_RS04860	COG0123	including yeast histone deacetylase and acetoin utilization protein
ADU64_RS04875	COG1960	acyl-CoA dehydrogenase activity
ADU64_RS04880	COG0450	alkyl hydroperoxide reductase
ADU64_RS04895	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ADU64_RS04900	COG4208	sulfate ABC transporter
ADU64_RS04905	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ADU64_RS04935	COG0335	large ribosomal subunit rRNA binding
ADU64_RS04950	COG0667	Aldo Keto reductase
ADU64_RS04960	COG2814	Major facilitator Superfamily
ADU64_RS04965	COG3161	chorismate lyase activity
ADU64_RS04970	COG1187	pseudouridine synthase activity
ADU64_RS04980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ADU64_RS05000	COG1999	signal sequence binding
ADU64_RS05005	COG0339	signal peptide processing
ADU64_RS05010	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ADU64_RS05015	COG4566	intracellular signal transduction
ADU64_RS05025	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ADU64_RS05030	COG0508	dehydrogenase complex catalyzes the overall conversion of
ADU64_RS05035	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ADU64_RS05040	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ADU64_RS05050	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ADU64_RS05055	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ADU64_RS05060	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ADU64_RS05065	COG0126	phosphoglycerate kinase activity
ADU64_RS05070	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ADU64_RS05075	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ADU64_RS05090	COG0625	glutathione transferase activity
ADU64_RS05125	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ADU64_RS05135	COG0521	Mo-molybdopterin cofactor biosynthetic process
ADU64_RS05145	COG0739	heme binding
ADU64_RS05155	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ADU64_RS05190	COG0745	RESPONSE REGULATOR receiver
ADU64_RS05205	COG0840	transmembrane signaling receptor activity
ADU64_RS05215	COG2201	protein-glutamate methylesterase activity
ADU64_RS05220	COG0745	RESPONSE REGULATOR receiver
ADU64_RS05225	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
ADU64_RS05250	COG0667	Aldo Keto reductase
ADU64_RS05260	COG4535	Mg2 and Co2 transporter CorC
ADU64_RS05265	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ADU64_RS05270	COG1702	phosphate starvation-inducible protein PhoH
ADU64_RS05275	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ADU64_RS05290	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ADU64_RS05295	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ADU64_RS05300	COG1862	Preprotein translocase
ADU64_RS05305	COG0343	queuine tRNA-ribosyltransferase activity
ADU64_RS05310	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ADU64_RS05315	COG2027	D-alanyl-D-alanine carboxypeptidase
ADU64_RS05320	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ADU64_RS05330	COG3468	outer membrane autotransporter barrel domain protein
ADU64_RS05345	COG3468	outer membrane autotransporter barrel domain protein
ADU64_RS05350	COG1648	precorrin-2 dehydrogenase activity
ADU64_RS05350	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ADU64_RS05375	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ADU64_RS05380	COG0741	lytic transglycosylase activity
ADU64_RS05385	COG0436	Aminotransferase
ADU64_RS05395	COG0280	phosphate acetyltransferase
ADU64_RS05395	COG0281	malic enzyme
ADU64_RS05405	COG2732	(Barnase) inhibitor
ADU64_RS05420	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ADU64_RS05445	COG0248	Ppx GppA phosphatase
ADU64_RS05455	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ADU64_RS05465	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ADU64_RS05470	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
ADU64_RS05475	COG1534	Rna-binding protein
ADU64_RS05505	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ADU64_RS05520	COG1295	ribonuclease BN
ADU64_RS05530	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ADU64_RS05535	COG0745	RESPONSE REGULATOR receiver
ADU64_RS05540	COG2205	protein histidine kinase activity
ADU64_RS05575	COG1022	Amp-dependent synthetase and ligase
ADU64_RS05590	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ADU64_RS05595	COG1028	Short-chain dehydrogenase reductase Sdr
ADU64_RS05605	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ADU64_RS05620	COG1136	(ABC) transporter
ADU64_RS05625	COG0084	hydrolase, TatD family'
ADU64_RS05655	COG0658	competence protein
ADU64_RS05655	COG2333	competence protein COMEC
ADU64_RS05665	COG0613	PHP domain protein
ADU64_RS05680	COG3539	Fimbrial protein
ADU64_RS05685	COG0281	malic enzyme
ADU64_RS05685	COG0280	phosphate acetyltransferase
ADU64_RS05695	COG1522	sequence-specific DNA binding
ADU64_RS05705	COG0567	Dehydrogenase, E1 component
ADU64_RS05710	COG0508	dehydrogenase complex catalyzes the overall conversion of
ADU64_RS05715	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ADU64_RS05720	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ADU64_RS05725	COG1028	Short-chain dehydrogenase reductase Sdr
ADU64_RS05730	COG0583	DNA-binding transcription factor activity
ADU64_RS05740	COG3181	Tripartite tricarboxylate transporter family receptor
ADU64_RS05765	COG0180	Tryptophanyl-tRNA synthetase
ADU64_RS05770	COG2183	response to ionizing radiation
ADU64_RS05775	COG1199	ATP-dependent helicase activity
ADU64_RS05785	COG0564	pseudouridine synthase activity
ADU64_RS05795	COG3243	poly(R)-hydroxyalkanoic acid synthase
ADU64_RS05800	COG1028	Short-chain dehydrogenase reductase Sdr
ADU64_RS05805	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
ADU64_RS05820	COG0672	)-iron permease
ADU64_RS05860	COG0583	DNA-binding transcription factor activity
ADU64_RS05870	COG2814	Major facilitator Superfamily
ADU64_RS05885	COG1619	proteins homologs of microcin C7 resistance protein MccF
ADU64_RS05900	COG2084	Dehydrogenase
ADU64_RS05905	COG3181	Tripartite tricarboxylate transporter family receptor
ADU64_RS05930	COG2988	succinylglutamate desuccinylase activity
ADU64_RS05955	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ADU64_RS05960	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ADU64_RS05960	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ADU64_RS05965	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ADU64_RS05970	COG0047	phosphoribosylformylglycinamidine synthase activity
ADU64_RS05970	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ADU64_RS05975	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
ADU64_RS05975	COG3210	domain, Protein
ADU64_RS05975	COG3064	Membrane
ADU64_RS06000	COG0235	Class ii aldolase
ADU64_RS06005	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ADU64_RS06010	COG0720	synthase
ADU64_RS06015	COG0602	queuosine metabolic process
ADU64_RS06040	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ADU64_RS06075	COG3181	Tripartite tricarboxylate transporter family receptor
ADU64_RS06105	COG3842	ATPase activity
ADU64_RS06115	COG0395	ABC-type sugar transport system, permease component
ADU64_RS06145	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ADU64_RS06150	COG0420	3'-5' exonuclease activity
ADU64_RS06195	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ADU64_RS06195	COG0519	Catalyzes the synthesis of GMP from XMP
ADU64_RS06210	COG3550	peptidyl-serine autophosphorylation
ADU64_RS06220	COG0477	Major facilitator Superfamily
ADU64_RS06235	COG1228	amidohydrolase
ADU64_RS06245	COG1116	anion transmembrane transporter activity
ADU64_RS06250	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ADU64_RS06290	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ADU64_RS06310	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ADU64_RS06340	COG2814	Major facilitator Superfamily
ADU64_RS06355	COG1280	lysine exporter protein (LysE YggA)
ADU64_RS06370	COG0747	negative chemotaxis
ADU64_RS06375	COG0601	transmembrane transport
ADU64_RS06380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ADU64_RS06385	COG4172	Belongs to the ABC transporter superfamily
ADU64_RS06390	COG1609	Transcriptional regulator
ADU64_RS06420	COG0586	Pfam SNARE associated Golgi protein
ADU64_RS06435	COG0500	methyltransferase
ADU64_RS06450	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ADU64_RS06460	COG0756	dUTP diphosphatase activity
ADU64_RS06475	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ADU64_RS06480	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ADU64_RS06485	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ADU64_RS06490	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ADU64_RS06490	COG0072	phenylalanine-tRNA ligase activity
ADU64_RS06495	COG0776	regulation of translation
ADU64_RS06565	COG0540	Belongs to the ATCase OTCase family
ADU64_RS06570	COG2974	May be involved in recombination
ADU64_RS06580	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ADU64_RS06585	COG0583	DNA-binding transcription factor activity
ADU64_RS06605	COG1028	Short-chain dehydrogenase reductase Sdr
ADU64_RS06620	COG3842	ATPase activity
ADU64_RS06625	COG1024	Enoyl-CoA hydratase
ADU64_RS06625	COG1250	3-hydroxyacyl-CoA dehydrogenase
ADU64_RS06645	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ADU64_RS06650	COG2137	regulation of response to DNA damage stimulus
ADU64_RS06660	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ADU64_RS06670	COG0045	succinate-CoA ligase (ADP-forming) activity
ADU64_RS06675	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ADU64_RS06680	COG0861	Integral membrane protein TerC family
ADU64_RS06685	COG0861	Integral membrane protein TerC family
ADU64_RS06690	COG0181	hydroxymethylbilane synthase activity
ADU64_RS06750	COG4964	Belongs to the GSP D family
ADU64_RS06780	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ADU64_RS06790	COG0583	DNA-binding transcription factor activity
ADU64_RS06800	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ADU64_RS06805	COG4311	Sarcosine oxidase, delta subunit
ADU64_RS06810	COG0446	pyridine nucleotide-disulphide oxidoreductase
ADU64_RS06810	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ADU64_RS06845	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ADU64_RS06850	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ADU64_RS06855	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ADU64_RS06860	COG0735	belongs to the Fur family
ADU64_RS06865	COG0497	DNA recombination
ADU64_RS06870	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ADU64_RS06875	COG1420	regulation of RNA biosynthetic process
ADU64_RS06880	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ADU64_RS06890	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ADU64_RS06900	COG0443	Heat shock 70 kDa protein
ADU64_RS06910	COG0612	Peptidase, M16
ADU64_RS06930	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ADU64_RS06975	COG0745	RESPONSE REGULATOR receiver
ADU64_RS06985	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
ADU64_RS06990	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
ADU64_RS06995	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ADU64_RS07010	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ADU64_RS07030	COG1193	negative regulation of DNA recombination
ADU64_RS07035	COG0492	ferredoxin-NADP+ reductase activity
ADU64_RS07040	COG1674	ftsk spoiiie
ADU64_RS07045	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ADU64_RS07050	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ADU64_RS07055	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ADU64_RS07080	COG3706	GGDEF domain
ADU64_RS07100	COG2814	Major facilitator Superfamily
ADU64_RS07130	COG3486	L-lysine 6-monooxygenase (NADPH) activity
ADU64_RS07145	COG1028	Short-chain dehydrogenase reductase Sdr
ADU64_RS07155	COG3022	response to hydroperoxide
ADU64_RS07165	COG1289	transmembrane transporter activity
ADU64_RS07185	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ADU64_RS07195	COG2197	response regulator
ADU64_RS07200	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ADU64_RS07205	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ADU64_RS07210	COG0189	ligase activity
ADU64_RS07220	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ADU64_RS07225	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ADU64_RS07235	COG1764	response to oxidative stress
ADU64_RS07240	COG2423	ornithine cyclodeaminase activity
ADU64_RS07250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ADU64_RS07255	COG0765	amino acid transport
ADU64_RS07260	COG0765	amino acid transport
ADU64_RS07265	COG1126	abc transporter atp-binding protein
ADU64_RS07320	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ADU64_RS07330	COG2944	sequence-specific DNA binding
ADU64_RS07340	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ADU64_RS07345	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ADU64_RS07350	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ADU64_RS07355	COG0009	L-threonylcarbamoyladenylate synthase
ADU64_RS07360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ADU64_RS07365	COG1414	Transcriptional regulator
ADU64_RS07380	COG0765	amino acid transport
ADU64_RS07385	COG1126	abc transporter atp-binding protein
ADU64_RS07390	COG0028	Belongs to the TPP enzyme family
ADU64_RS07405	COG0028	Belongs to the TPP enzyme family
ADU64_RS07410	COG0583	DNA-binding transcription factor activity
ADU64_RS07415	COG4974	Belongs to the 'phage' integrase family
ADU64_RS07420	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ADU64_RS07425	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
ADU64_RS07440	COG1686	Belongs to the peptidase S11 family
ADU64_RS07450	COG2814	Major facilitator Superfamily
ADU64_RS07460	COG1074	ATP-dependent DNA helicase activity
ADU64_RS07475	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ADU64_RS07480	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ADU64_RS07485	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ADU64_RS07505	COG2321	neutral zinc metallopeptidase
ADU64_RS07510	COG0009	L-threonylcarbamoyladenylate synthase
ADU64_RS07555	COG3360	Dodecin
ADU64_RS07560	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ADU64_RS07565	COG2850	peptidyl-arginine hydroxylation
ADU64_RS07570	COG3539	Fimbrial protein
ADU64_RS07575	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
ADU64_RS07580	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ADU64_RS07600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ADU64_RS07605	COG0765	amino acid transport
ADU64_RS07610	COG1126	abc transporter atp-binding protein
ADU64_RS07615	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ADU64_RS07620	COG1758	RNA polymerase activity
ADU64_RS07625	COG0194	GDP metabolic process
ADU64_RS07630	COG3258	Cytochrome c
ADU64_RS07635	COG2863	cytochrome
ADU64_RS07640	COG1028	Short-chain dehydrogenase reductase Sdr
ADU64_RS07645	COG0791	NLP P60 protein
ADU64_RS07650	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ADU64_RS07670	COG1561	YicC-like family, N-terminal region
ADU64_RS07675	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ADU64_RS07690	COG0840	transmembrane signaling receptor activity
ADU64_RS07695	COG2200	EAL domain
ADU64_RS07695	COG2199	diguanylate cyclase activity
ADU64_RS07700	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ADU64_RS07710	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ADU64_RS07715	COG0174	glutamine synthetase
ADU64_RS07725	COG2204	response regulator
ADU64_RS07730	COG0583	DNA-binding transcription factor activity
ADU64_RS07735	COG1741	Belongs to the pirin family
ADU64_RS07740	COG1741	Belongs to the pirin family
ADU64_RS07750	COG3842	ATPase activity
ADU64_RS07755	COG1178	ABC-type Fe3 transport system permease component
ADU64_RS07760	COG1840	ABC-type Fe3 transport system, periplasmic component
ADU64_RS07770	COG0583	DNA-binding transcription factor activity
ADU64_RS07780	COG0656	L-ascorbic acid biosynthetic process
ADU64_RS07795	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ADU64_RS07800	COG0583	DNA-binding transcription factor activity
ADU64_RS07815	COG0783	Belongs to the Dps family
ADU64_RS07835	COG0463	Glycosyl transferase, family 2
ADU64_RS07855	COG0438	transferase activity, transferring glycosyl groups
ADU64_RS07870	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ADU64_RS07895	COG0300	oxidoreductase activity
ADU64_RS07940	COG0861	Integral membrane protein TerC family
ADU64_RS07945	COG1028	Short-chain dehydrogenase reductase Sdr
ADU64_RS07965	COG0714	Associated with various cellular activities
ADU64_RS08000	COG3119	arylsulfatase activity
ADU64_RS08025	COG2197	response regulator
ADU64_RS08035	COG2944	sequence-specific DNA binding
ADU64_RS08040	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
ADU64_RS08045	COG0625	glutathione transferase activity
ADU64_RS08075	COG0179	Fumarylacetoacetate (FAA) hydrolase
ADU64_RS08080	COG1028	Short-chain dehydrogenase reductase Sdr
ADU64_RS08125	COG0431	NADPH-dependent FMN reductase
ADU64_RS08155	COG1028	Short-chain dehydrogenase reductase Sdr
ADU64_RS08160	COG0583	DNA-binding transcription factor activity
ADU64_RS08175	COG3181	Tripartite tricarboxylate transporter family receptor
ADU64_RS08180	COG2111	Na H antiporter
ADU64_RS08180	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ADU64_RS08185	COG1006	Multisubunit Na H antiporter MnhC subunit
ADU64_RS08190	COG0651	ATP synthesis coupled electron transport
ADU64_RS08195	COG1863	multisubunit Na H antiporter MnhE subunit
ADU64_RS08200	COG2212	antiporter activity
ADU64_RS08225	COG0590	tRNA wobble adenosine to inosine editing
ADU64_RS08230	COG1619	proteins homologs of microcin C7 resistance protein MccF
ADU64_RS08235	COG1024	Enoyl-CoA hydratase
ADU64_RS08250	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ADU64_RS08255	COG0488	(ABC) transporter
ADU64_RS08290	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ADU64_RS08290	COG1017	nitric oxide dioxygenase activity
ADU64_RS08295	COG1959	2 iron, 2 sulfur cluster binding
ADU64_RS08300	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ADU64_RS08320	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ADU64_RS08325	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ADU64_RS08330	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ADU64_RS08335	COG0084	hydrolase, TatD family'
ADU64_RS08350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ADU64_RS08360	COG1126	abc transporter atp-binding protein
ADU64_RS08365	COG0010	Belongs to the arginase family
ADU64_RS08370	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ADU64_RS08375	COG1012	belongs to the aldehyde dehydrogenase family
ADU64_RS08385	COG0028	Belongs to the TPP enzyme family
ADU64_RS08395	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ADU64_RS08395	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ADU64_RS08405	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ADU64_RS08420	COG3189	MarR family transcriptional regulator
ADU64_RS08425	COG2010	Cytochrome c
ADU64_RS08450	COG4336	lyase activity
ADU64_RS08460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ADU64_RS08460	COG2205	protein histidine kinase activity
ADU64_RS08465	COG2197	response regulator
ADU64_RS08470	COG3210	domain, Protein
ADU64_RS08470	COG3064	Membrane
ADU64_RS08470	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
ADU64_RS08480	COG3121	Chaperone
ADU64_RS08485	COG3188	usher protein
ADU64_RS08490	COG3539	Fimbrial protein
ADU64_RS08495	COG2831	hemolysin activation secretion protein
ADU64_RS08510	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ADU64_RS08535	COG0583	DNA-binding transcription factor activity
ADU64_RS08560	COG0668	transmembrane transport
ADU64_RS08580	COG0483	inositol monophosphate 1-phosphatase activity
ADU64_RS08585	COG1253	flavin adenine dinucleotide binding
ADU64_RS08590	COG1968	undecaprenyl-diphosphatase activity
ADU64_RS08595	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ADU64_RS08610	COG0215	cysteine-tRNA ligase activity
ADU64_RS08620	COG0825	malonyl-CoA metabolic process
ADU64_RS08630	COG0037	tRNA processing
ADU64_RS08635	COG0527	aspartate kinase activity
ADU64_RS08660	COG1250	3-hydroxyacyl-CoA dehydrogenase
ADU64_RS08665	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ADU64_RS08665	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ADU64_RS08680	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ADU64_RS08685	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
ADU64_RS08690	COG1028	Short-chain dehydrogenase reductase Sdr
ADU64_RS08700	COG0583	DNA-binding transcription factor activity
ADU64_RS08730	COG3842	ATPase activity
ADU64_RS08740	COG1902	pentaerythritol trinitrate reductase activity
ADU64_RS08740	COG0446	pyridine nucleotide-disulphide oxidoreductase
ADU64_RS08745	COG1414	Transcriptional regulator
ADU64_RS08750	COG1832	CoA-binding protein
ADU64_RS08760	COG0251	oxidation-reduction process
ADU64_RS08785	COG1902	pentaerythritol trinitrate reductase activity
ADU64_RS08795	COG1215	transferase activity, transferring glycosyl groups
ADU64_RS08800	COG1649	PFAM Uncharacterised BCR, COG1649
ADU64_RS08800	COG0726	polysaccharide deacetylase
ADU64_RS08820	COG1846	Transcriptional regulator
ADU64_RS08835	COG3468	outer membrane autotransporter barrel domain protein
ADU64_RS08840	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ADU64_RS08850	COG0556	nucleotide-excision repair
ADU64_RS08855	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ADU64_RS08865	COG1104	cysteine desulfurase activity
ADU64_RS08870	COG0822	iron-sulfur transferase activity
ADU64_RS08875	COG0316	Belongs to the HesB IscA family
ADU64_RS08880	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ADU64_RS08885	COG0443	Heat shock 70 kDa protein
ADU64_RS08890	COG0633	Ferredoxin
ADU64_RS08910	COG1024	Enoyl-CoA hydratase
ADU64_RS08925	COG3395	kinase activity
ADU64_RS08930	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ADU64_RS08945	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ADU64_RS08955	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ADU64_RS08980	COG0747	negative chemotaxis
ADU64_RS08985	COG0601	transmembrane transport
ADU64_RS08990	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ADU64_RS08995	COG4172	Belongs to the ABC transporter superfamily
ADU64_RS09000	COG0154	amidase activity
ADU64_RS09045	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ADU64_RS09050	COG0425	Belongs to the sulfur carrier protein TusA family
ADU64_RS09060	COG0228	four-way junction DNA binding
ADU64_RS09065	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ADU64_RS09070	COG0336	Belongs to the RNA methyltransferase TrmD family
ADU64_RS09075	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ADU64_RS09095	COG0642	Histidine kinase
ADU64_RS09110	COG0525	valine-tRNA ligase activity
ADU64_RS09115	COG0105	UTP biosynthetic process
ADU64_RS09120	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ADU64_RS09130	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ADU64_RS09135	COG0124	histidyl-tRNA synthetase
ADU64_RS09140	COG2976	Protein conserved in bacteria
ADU64_RS09145	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ADU64_RS09150	COG1160	GTP binding
ADU64_RS09155	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ADU64_RS09160	COG1923	regulation of RNA biosynthetic process
ADU64_RS09165	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ADU64_RS09170	COG0330	HflC and HflK could
ADU64_RS09175	COG0330	HflC and HflK could
ADU64_RS09180	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ADU64_RS09185	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ADU64_RS09190	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ADU64_RS09195	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ADU64_RS09205	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ADU64_RS09240	COG0628	permease
ADU64_RS09245	COG0842	Transport permease protein
ADU64_RS09250	COG1131	(ABC) transporter
ADU64_RS09320	COG0156	8-amino-7-oxononanoate synthase activity
ADU64_RS09330	COG4106	trans-aconitate 2-methyltransferase activity
ADU64_RS09330	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ADU64_RS09335	COG1380	Effector of murein hydrolase LrgA
ADU64_RS09355	COG3284	Transcriptional regulator
ADU64_RS09360	COG1012	belongs to the aldehyde dehydrogenase family
ADU64_RS09375	COG2733	membrane
ADU64_RS09380	COG0583	DNA-binding transcription factor activity
ADU64_RS09385	COG0384	phenazine biosynthesis protein PhzF
ADU64_RS09390	COG5507	3-demethylubiquinone-9 3-methyltransferase
ADU64_RS09395	COG2169	Transcriptional regulator
ADU64_RS09425	COG0659	secondary active sulfate transmembrane transporter activity
ADU64_RS09450	COG1132	(ABC) transporter
ADU64_RS09495	COG2207	Transcriptional regulator
ADU64_RS09630	COG2346	COG2346, Truncated hemoglobins
ADU64_RS09675	COG0183	Belongs to the thiolase family
ADU64_RS09690	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ADU64_RS09695	COG0633	Ferredoxin
ADU64_RS09705	COG1024	Enoyl-CoA hydratase
ADU64_RS09715	COG4638	Rieske (2fe-2S)
ADU64_RS09725	COG0559	Belongs to the binding-protein-dependent transport system permease family
ADU64_RS09745	COG2224	Isocitrate lyase
ADU64_RS09750	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ADU64_RS09750	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ADU64_RS09765	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ADU64_RS09770	COG0322	excinuclease ABC activity
ADU64_RS09775	COG1472	Belongs to the glycosyl hydrolase 3 family
ADU64_RS09780	COG0736	holo-[acyl-carrier-protein] synthase activity
ADU64_RS09785	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ADU64_RS09795	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ADU64_RS09800	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ADU64_RS09825	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
ADU64_RS09840	COG2032	superoxide dismutase activity
ADU64_RS09855	COG1024	Enoyl-CoA hydratase
ADU64_RS09865	COG1802	Transcriptional regulator
ADU64_RS09875	COG0183	Belongs to the thiolase family
ADU64_RS09880	COG1942	4-Oxalocrotonate Tautomerase
ADU64_RS09890	COG4176	ABC-type proline glycine betaine transport system permease component
ADU64_RS09905	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ADU64_RS09910	COG2814	Major facilitator Superfamily
ADU64_RS09915	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ADU64_RS09920	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ADU64_RS09950	COG2814	Major facilitator Superfamily
ADU64_RS09955	COG0495	leucyl-tRNA aminoacylation
ADU64_RS09970	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ADU64_RS09980	COG0154	amidase activity
ADU64_RS09985	COG1250	3-hydroxyacyl-CoA dehydrogenase
ADU64_RS10040	COG0427	acetyl-CoA hydrolase
ADU64_RS10045	COG0583	DNA-binding transcription factor activity
ADU64_RS10065	COG0730	response to heat
ADU64_RS10070	COG0697	spore germination
ADU64_RS10105	COG2885	chlorophyll binding
ADU64_RS10130	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ADU64_RS10135	COG3384	dioxygenase
ADU64_RS10150	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ADU64_RS10155	COG3474	cytochrome
ADU64_RS10165	COG1595	DNA-templated transcription, initiation
ADU64_RS10180	COG2204	response regulator
ADU64_RS10220	COG4964	Belongs to the GSP D family
ADU64_RS10270	COG1846	Transcriptional regulator
ADU64_RS10275	COG4172	Belongs to the ABC transporter superfamily
ADU64_RS10280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ADU64_RS10285	COG0601	transmembrane transport
ADU64_RS10290	COG0747	negative chemotaxis
ADU64_RS10300	COG0598	Magnesium transport protein CorA
ADU64_RS10305	COG0210	DNA helicase
ADU64_RS10320	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ADU64_RS10325	COG1012	belongs to the aldehyde dehydrogenase family
ADU64_RS10330	COG0483	inositol monophosphate 1-phosphatase activity
ADU64_RS10335	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ADU64_RS10345	COG1045	serine acetyltransferase
ADU64_RS10350	COG0166	Belongs to the GPI family
ADU64_RS10365	COG2197	response regulator
ADU64_RS10385	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ADU64_RS10400	COG1960	acyl-CoA dehydrogenase activity
ADU64_RS10405	COG1028	Short-chain dehydrogenase reductase Sdr
ADU64_RS10410	COG0183	Belongs to the thiolase family
ADU64_RS10420	COG1024	Enoyl-CoA hydratase
ADU64_RS10435	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ADU64_RS10440	COG0583	DNA-binding transcription factor activity
ADU64_RS10445	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ADU64_RS10450	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ADU64_RS10455	COG0740	serine-type endopeptidase activity
ADU64_RS10460	COG0544	peptidyl-prolyl cis-trans isomerase activity
ADU64_RS10480	COG1278	Cold shock
ADU64_RS10515	COG2171	N-acyltransferase activity
ADU64_RS10520	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ADU64_RS10525	COG2890	protein-(glutamine-N5) methyltransferase activity
ADU64_RS10530	COG0488	(ABC) transporter
ADU64_RS10535	COG4771	TonB-dependent receptor
ADU64_RS10540	COG0210	DNA helicase
ADU64_RS10560	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ADU64_RS10565	COG0196	riboflavin kinase activity
ADU64_RS10570	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ADU64_RS10575	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ADU64_RS10580	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ADU64_RS10590	COG1522	sequence-specific DNA binding
ADU64_RS10610	COG2951	lytic endotransglycosylase activity
ADU64_RS10615	COG2833	Protein of unknown function (DUF455)
ADU64_RS10635	COG0189	ligase activity
ADU64_RS10635	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ADU64_RS10640	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ADU64_RS10640	COG1181	Belongs to the D-alanine--D-alanine ligase family
ADU64_RS10645	COG3237	CsbD-like
ADU64_RS10655	COG2823	Periplasmic or secreted lipoprotein
ADU64_RS10665	COG4181	ATPase activity
ADU64_RS10675	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ADU64_RS10680	COG0584	glycerophosphoryl diester phosphodiesterase
ADU64_RS10685	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ADU64_RS10695	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ADU64_RS10695	COG0678	peroxiredoxin activity
ADU64_RS10705	COG0789	Transcriptional regulator
ADU64_RS10710	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ADU64_RS10740	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ADU64_RS10745	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ADU64_RS10755	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ADU64_RS10760	COG2252	PERMEase
ADU64_RS10770	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ADU64_RS10805	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ADU64_RS10810	COG2358	TRAP transporter, solute receptor (TAXI family
ADU64_RS10845	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ADU64_RS10850	COG1366	Belongs to the anti-sigma-factor antagonist family
ADU64_RS10855	COG2172	sigma factor antagonist activity
ADU64_RS10860	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ADU64_RS10870	COG2208	phosphoserine phosphatase activity
ADU64_RS10870	COG2770	Histidine kinase
ADU64_RS10895	COG1595	DNA-templated transcription, initiation
ADU64_RS10910	COG4792	protein secretion
ADU64_RS10915	COG4791	protein targeting
ADU64_RS10920	COG4794	Type iii secretion
ADU64_RS10925	COG4790	Type iii secretion
ADU64_RS10960	COG4669	(LipO)protein
ADU64_RS11025	COG4789	Type iii secretion
ADU64_RS11055	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ADU64_RS11060	COG0840	transmembrane signaling receptor activity
ADU64_RS11065	COG2233	PERMEase
ADU64_RS11085	COG0492	ferredoxin-NADP+ reductase activity
ADU64_RS11090	COG1840	ABC-type Fe3 transport system, periplasmic component
ADU64_RS11095	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ADU64_RS11100	COG1178	ABC-type Fe3 transport system permease component
ADU64_RS11105	COG3842	ATPase activity
ADU64_RS11110	COG0583	DNA-binding transcription factor activity
ADU64_RS11130	COG0501	Belongs to the peptidase M48B family
ADU64_RS11140	COG0697	spore germination
ADU64_RS11150	COG1846	Transcriptional regulator
ADU64_RS11160	COG1566	PFAM secretion protein HlyD family protein
ADU64_RS11165	COG2814	Major facilitator Superfamily
ADU64_RS11170	COG0473	3-isopropylmalate dehydrogenase activity
ADU64_RS11180	COG0747	negative chemotaxis
ADU64_RS11190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ADU64_RS11205	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ADU64_RS11230	COG1012	belongs to the aldehyde dehydrogenase family
ADU64_RS11240	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ADU64_RS11245	COG1115	amino acid carrier protein
ADU64_RS11250	COG0433	COG0433 Predicted ATPase
ADU64_RS11255	COG0217	transcriptional regulatory protein
ADU64_RS11260	COG0151	Belongs to the GarS family
ADU64_RS11265	COG0408	coproporphyrinogen oxidase activity
ADU64_RS11270	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ADU64_RS11275	COG0799	negative regulation of ribosome biogenesis
ADU64_RS11280	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ADU64_RS11285	COG0424	maF-like protein
ADU64_RS11290	COG3468	outer membrane autotransporter barrel domain protein
ADU64_RS11330	COG1530	ribonuclease E activity
ADU64_RS11335	COG0077	Prephenate dehydratase
ADU64_RS11350	COG1132	(ABC) transporter
ADU64_RS11355	COG0859	PFAM glycosyl transferase family 9
ADU64_RS11380	COG2194	sulfuric ester hydrolase activity
ADU64_RS11385	COG0438	transferase activity, transferring glycosyl groups
ADU64_RS11390	COG0463	Glycosyl transferase, family 2
ADU64_RS11395	COG0726	polysaccharide deacetylase
ADU64_RS11400	COG0438	transferase activity, transferring glycosyl groups
ADU64_RS11415	COG1643	Atp-dependent helicase
ADU64_RS11420	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ADU64_RS11420	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ADU64_RS11425	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
ADU64_RS11435	COG0704	Plays a role in the regulation of phosphate uptake
ADU64_RS11440	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ADU64_RS11445	COG1960	acyl-CoA dehydrogenase activity
ADU64_RS11470	COG1177	transmembrane transport
ADU64_RS11475	COG1176	ABC-type spermidine putrescine transport system, permease component I
ADU64_RS11480	COG3842	ATPase activity
ADU64_RS11485	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ADU64_RS11500	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
ADU64_RS11505	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ADU64_RS11515	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ADU64_RS11515	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ADU64_RS11535	COG0372	Belongs to the citrate synthase family
ADU64_RS11540	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
ADU64_RS11545	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ADU64_RS11550	COG1053	succinate dehydrogenase
ADU64_RS11555	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ADU64_RS11560	COG2009	succinate dehydrogenase
ADU64_RS11565	COG2188	Transcriptional regulator
ADU64_RS11570	COG0039	L-malate dehydrogenase activity
ADU64_RS11600	COG1981	membrane
ADU64_RS11625	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ADU64_RS11635	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ADU64_RS11665	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ADU64_RS11670	COG0148	phosphopyruvate hydratase activity
ADU64_RS11680	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ADU64_RS11685	COG0504	CTP synthase activity
ADU64_RS11710	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ADU64_RS11720	COG0747	negative chemotaxis
ADU64_RS11725	COG4172	Belongs to the ABC transporter superfamily
ADU64_RS11730	COG1446	asparaginase
ADU64_RS11760	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ADU64_RS11775	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
ADU64_RS11780	COG0697	spore germination
ADU64_RS11785	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ADU64_RS11795	COG3193	protein, possibly involved in utilization of glycolate and propanediol
ADU64_RS11800	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ADU64_RS11805	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ADU64_RS11810	COG0791	NLP P60 protein
ADU64_RS11825	COG0583	DNA-binding transcription factor activity
ADU64_RS11840	COG0583	DNA-binding transcription factor activity
ADU64_RS11850	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ADU64_RS11865	COG0670	Belongs to the BI1 family
ADU64_RS11870	COG3181	Tripartite tricarboxylate transporter family receptor
ADU64_RS11880	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ADU64_RS11890	COG1381	Involved in DNA repair and RecF pathway recombination
ADU64_RS11895	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ADU64_RS11900	COG0571	ribonuclease III activity
ADU64_RS11905	COG0681	Belongs to the peptidase S26 family
ADU64_RS11910	COG0481	GTPase activity
ADU64_RS11915	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ADU64_RS11940	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ADU64_RS11945	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ADU64_RS11960	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ADU64_RS11965	COG0416	fatty acid biosynthetic process
ADU64_RS11970	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ADU64_RS11975	COG1399	metal-binding, possibly nucleic acid-binding protein
ADU64_RS11980	COG0424	maF-like protein
ADU64_RS11990	COG3023	N-Acetylmuramoyl-L-alanine amidase
ADU64_RS11995	COG1289	transmembrane transporter activity
ADU64_RS12005	COG3022	response to hydroperoxide
ADU64_RS12020	COG0135	phosphoribosylanthranilate isomerase activity
ADU64_RS12035	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ADU64_RS12040	COG0101	tRNA pseudouridine synthase activity
ADU64_RS12050	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ADU64_RS12055	COG0473	3-isopropylmalate dehydrogenase activity
ADU64_RS12060	COG0066	3-isopropylmalate dehydratase activity
ADU64_RS12065	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ADU64_RS12075	COG1122	ATPase activity
ADU64_RS12105	COG0437	4 iron, 4 sulfur cluster binding
ADU64_RS12110	COG0243	molybdopterin cofactor binding
ADU64_RS12110	COG3383	formate dehydrogenase (NAD+) activity
ADU64_RS12140	COG0489	protein tyrosine kinase activity
ADU64_RS12145	COG0746	molybdenum cofactor guanylyltransferase activity
ADU64_RS12150	COG0303	'Molybdopterin
ADU64_RS12155	COG1763	Mo-molybdopterin cofactor biosynthetic process
ADU64_RS12165	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ADU64_RS12170	COG5001	Diguanylate cyclase
ADU64_RS12190	COG3842	ATPase activity
ADU64_RS12200	COG0406	alpha-ribazole phosphatase activity
ADU64_RS12210	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ADU64_RS12215	COG0505	Belongs to the CarA family
ADU64_RS12220	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ADU64_RS12250	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ADU64_RS12255	COG1960	acyl-CoA dehydrogenase activity
ADU64_RS12265	COG2867	negative regulation of translational initiation
ADU64_RS12275	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ADU64_RS12280	COG3706	GGDEF domain
ADU64_RS12285	COG0330	HflC and HflK could
ADU64_RS12300	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ADU64_RS12300	COG0519	Catalyzes the synthesis of GMP from XMP
ADU64_RS12310	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
ADU64_RS12315	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ADU64_RS12320	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ADU64_RS12325	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ADU64_RS12335	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ADU64_RS12340	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ADU64_RS12345	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
ADU64_RS12350	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ADU64_RS12355	COG0750	zinc metalloprotease
ADU64_RS12360	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ADU64_RS12370	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ADU64_RS12375	COG0233	cytoplasmic translational termination
ADU64_RS12380	COG0528	UMP kinase activity
ADU64_RS12385	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ADU64_RS12390	COG0052	Belongs to the universal ribosomal protein uS2 family
ADU64_RS12395	COG0024	Methionine aminopeptidase
ADU64_RS12400	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
ADU64_RS12430	COG0285	dihydrofolate synthase activity
ADU64_RS12465	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ADU64_RS12475	COG1677	Flagellar hook-basal body complex protein FliE
ADU64_RS12485	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ADU64_RS12495	COG1157	protein secretion by the type III secretion system
ADU64_RS12520	COG1580	Controls the rotational direction of flagella during chemotaxis
ADU64_RS12540	COG1338	Plays a role in the flagellum-specific transport system
ADU64_RS12560	COG0840	transmembrane signaling receptor activity
ADU64_RS12565	COG0840	transmembrane signaling receptor activity
ADU64_RS12570	COG0840	transmembrane signaling receptor activity
ADU64_RS12580	COG1256	bacterial-type flagellum assembly
ADU64_RS12590	COG1706	bacterial-type flagellum-dependent cell motility
ADU64_RS12595	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
ADU64_RS12610	COG1749	Flagellar hook protein flgE
ADU64_RS12620	COG1558	bacterial-type flagellum-dependent cell motility
ADU64_RS12625	COG1815	bacterial-type flagellum-dependent cell motility
ADU64_RS12665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ADU64_RS12670	COG0765	amino acid transport
ADU64_RS12675	COG1126	abc transporter atp-binding protein
ADU64_RS12690	COG4948	Mandelate Racemase Muconate Lactonizing
ADU64_RS12695	COG3181	Tripartite tricarboxylate transporter family receptor
ADU64_RS12705	COG0066	3-isopropylmalate dehydratase activity
ADU64_RS12720	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ADU64_RS12730	COG3181	Tripartite tricarboxylate transporter family receptor
ADU64_RS12740	COG1802	Transcriptional regulator
ADU64_RS12755	COG0583	DNA-binding transcription factor activity
ADU64_RS12775	COG1695	Transcriptional regulator
ADU64_RS12785	COG3568	Endonuclease Exonuclease Phosphatase
ADU64_RS12790	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ADU64_RS12805	COG0392	lysyltransferase activity
ADU64_RS12845	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ADU64_RS12855	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ADU64_RS12875	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
ADU64_RS12905	COG0667	Aldo Keto reductase
ADU64_RS12920	COG2259	Doxx family
ADU64_RS12955	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ADU64_RS12975	COG0386	Belongs to the glutathione peroxidase family
ADU64_RS12980	COG0625	glutathione transferase activity
ADU64_RS13005	COG0688	phosphatidylethanolamine metabolic process
ADU64_RS13015	COG1464	Belongs to the NlpA lipoprotein family
ADU64_RS13030	COG2363	Small membrane protein
ADU64_RS13055	COG3842	ATPase activity
ADU64_RS13060	COG0395	ABC-type sugar transport system, permease component
ADU64_RS13065	COG1175	transmembrane transport
ADU64_RS13070	COG1653	transport
ADU64_RS13080	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ADU64_RS13095	COG0559	Belongs to the binding-protein-dependent transport system permease family
ADU64_RS13115	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ADU64_RS13130	COG0697	spore germination
ADU64_RS13145	COG2311	Membrane
ADU64_RS13170	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ADU64_RS13180	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ADU64_RS13185	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ADU64_RS13190	COG1760	l-serine dehydratase
ADU64_RS13195	COG1283	sodium-dependent phosphate transmembrane transporter activity
ADU64_RS13200	COG0412	Dienelactone hydrolase
ADU64_RS13215	COG1611	Belongs to the LOG family
ADU64_RS13235	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ADU64_RS13240	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ADU64_RS13245	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ADU64_RS13250	COG2251	uridine kinase activity
ADU64_RS13250	COG0195	Participates in both transcription termination and antitermination
ADU64_RS13255	COG0779	Required for maturation of 30S ribosomal subunits
ADU64_RS13260	COG1187	pseudouridine synthase activity
ADU64_RS13265	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ADU64_RS13275	COG0583	DNA-binding transcription factor activity
ADU64_RS13285	COG0523	cobalamin synthesis protein
ADU64_RS13305	COG0625	glutathione transferase activity
ADU64_RS13310	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ADU64_RS13315	COG1047	Peptidyl-prolyl cis-trans
ADU64_RS13320	COG2003	Belongs to the UPF0758 family
ADU64_RS13325	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
ADU64_RS13330	COG3483	tryptophan 2,3-dioxygenase activity
ADU64_RS13335	COG0254	rRNA binding
ADU64_RS13345	COG0534	Mate efflux family protein
ADU64_RS13365	COG2304	oxidoreductase activity
ADU64_RS13385	COG1028	Short-chain dehydrogenase reductase Sdr
ADU64_RS13390	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ADU64_RS13395	COG1562	ergosterol biosynthetic process
ADU64_RS13400	COG1562	ergosterol biosynthetic process
ADU64_RS13405	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
ADU64_RS13405	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
ADU64_RS13410	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ADU64_RS13420	COG0842	Transport permease protein
ADU64_RS13425	COG1131	(ABC) transporter
ADU64_RS13445	COG1477	protein flavinylation
ADU64_RS13460	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
ADU64_RS13475	COG5564	TIM-barrel signal transduction protein
ADU64_RS13480	COG5441	Belongs to the UPF0261 family
ADU64_RS13490	COG3468	outer membrane autotransporter barrel domain protein
ADU64_RS13495	COG3468	outer membrane autotransporter barrel domain protein
ADU64_RS13510	COG0542	response to heat
ADU64_RS13515	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ADU64_RS13530	COG0494	nUDIX hydrolase
ADU64_RS13535	COG3530	Putative quorum-sensing-regulated virulence factor
ADU64_RS13545	COG1595	DNA-templated transcription, initiation
ADU64_RS13550	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ADU64_RS13585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ADU64_RS13590	COG0765	amino acid transport
ADU64_RS13595	COG0765	amino acid transport
ADU64_RS13625	COG3539	Fimbrial protein
ADU64_RS13635	COG2050	protein possibly involved in aromatic compounds catabolism
ADU64_RS13640	COG1024	Enoyl-CoA hydratase
ADU64_RS13645	COG1012	belongs to the aldehyde dehydrogenase family
ADU64_RS13655	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ADU64_RS13660	COG2151	metal-sulfur cluster biosynthetic enzyme
ADU64_RS13665	COG3396	Phenylacetate-CoA oxygenase
ADU64_RS13670	COG3460	Phenylacetate-CoA oxygenase
ADU64_RS13675	COG3396	Phenylacetate-CoA oxygenase
ADU64_RS13680	COG3327	negative regulation of DNA-templated transcription, initiation
ADU64_RS13690	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ADU64_RS13695	COG0501	Belongs to the peptidase M48B family
ADU64_RS13700	COG1162	GTPase activity
ADU64_RS13705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ADU64_RS13710	COG0601	transmembrane transport
ADU64_RS13715	COG0747	negative chemotaxis
ADU64_RS13760	COG0668	transmembrane transport
ADU64_RS13765	COG0165	Argininosuccinate lyase
ADU64_RS13785	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ADU64_RS13790	COG0303	'Molybdopterin
ADU64_RS13795	COG0521	Mo-molybdopterin cofactor biosynthetic process
ADU64_RS13810	COG0315	cyclic pyranopterin monophosphate synthase activity
ADU64_RS13820	COG0412	Dienelactone hydrolase
ADU64_RS13830	COG0678	peroxiredoxin activity
ADU64_RS13840	COG0697	spore germination
ADU64_RS13845	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ADU64_RS13870	COG0789	Transcriptional regulator
ADU64_RS13890	COG1028	Short-chain dehydrogenase reductase Sdr
ADU64_RS13900	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ADU64_RS13905	COG1845	cytochrome c oxidase, subunit III
ADU64_RS13910	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ADU64_RS13920	COG0477	Major facilitator Superfamily
ADU64_RS13950	COG3468	outer membrane autotransporter barrel domain protein
ADU64_RS13960	COG1309	transcriptional regulator
ADU64_RS13965	COG2271	Major facilitator Superfamily
ADU64_RS14000	COG0506	proline dehydrogenase activity
ADU64_RS14000	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ADU64_RS14000	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ADU64_RS14010	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ADU64_RS14010	COG3008	intermembrane lipid transfer
ADU64_RS14015	COG2995	paraquat-inducible protein a
ADU64_RS14020	COG0542	response to heat
ADU64_RS14025	COG4953	penicillin-binding protein 1C
ADU64_RS14035	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ADU64_RS14040	COG1278	Cold shock
ADU64_RS14050	COG0183	Belongs to the thiolase family
ADU64_RS14055	COG0038	chloride channel
ADU64_RS14060	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ADU64_RS14065	COG1570	exodeoxyribonuclease VII activity
ADU64_RS14075	COG0811	peptide transport
ADU64_RS14080	COG0848	biopolymer transport protein
ADU64_RS14085	COG1663	tetraacyldisaccharide 4'-kinase activity
ADU64_RS14090	COG2835	tetraacyldisaccharide 4'-kinase activity
ADU64_RS14095	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ADU64_RS14100	COG0563	adenylate kinase activity
ADU64_RS14110	COG0728	peptidoglycan biosynthetic process
ADU64_RS14120	COG0268	Binds directly to 16S ribosomal RNA
ADU64_RS14150	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ADU64_RS14175	COG0436	Aminotransferase
ADU64_RS14180	COG3737	Protein of unknown function (DUF498/DUF598)
ADU64_RS14185	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ADU64_RS14190	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ADU64_RS14195	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ADU64_RS14205	COG0305	Participates in initiation and elongation during chromosome replication
ADU64_RS14215	COG0359	binds to the 23S rRNA
ADU64_RS14220	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ADU64_RS14225	COG2965	DNA replication, synthesis of RNA primer
ADU64_RS14230	COG0360	Binds together with S18 to 16S ribosomal RNA
ADU64_RS14235	COG1469	GTP cyclohydrolase I activity
ADU64_RS14240	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ADU64_RS14245	COG0142	geranyltranstransferase activity
ADU64_RS14250	COG1722	exodeoxyribonuclease VII activity
ADU64_RS14260	COG3181	Tripartite tricarboxylate transporter family receptor
ADU64_RS14280	COG2239	Acts as a magnesium transporter
ADU64_RS14290	COG2855	membrane
ADU64_RS14300	COG1473	amidohydrolase
ADU64_RS14305	COG0318	PFAM AMP-dependent synthetase and ligase
ADU64_RS14330	COG1501	Belongs to the glycosyl hydrolase 31 family
ADU64_RS14335	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ADU64_RS14340	COG2011	ABC-type metal ion transport system permease component
ADU64_RS14360	COG1454	alcohol dehydrogenase
ADU64_RS14390	COG2186	Transcriptional regulator
ADU64_RS14395	COG3181	Tripartite tricarboxylate transporter family receptor
ADU64_RS14415	COG1175	transmembrane transport
ADU64_RS14420	COG0395	ABC-type sugar transport system, permease component
ADU64_RS14425	COG3842	ATPase activity
ADU64_RS14430	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ADU64_RS14440	COG1653	transport
ADU64_RS14460	COG2818	Glycosylase
ADU64_RS14465	COG2982	Protein involved in outer membrane biogenesis
ADU64_RS14475	COG1309	transcriptional regulator
ADU64_RS14480	COG1028	Short-chain dehydrogenase reductase Sdr
ADU64_RS14540	COG0583	DNA-binding transcription factor activity
ADU64_RS14545	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ADU64_RS14550	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ADU64_RS14565	COG1028	Short-chain dehydrogenase reductase Sdr
ADU64_RS14570	COG0477	Major facilitator Superfamily
ADU64_RS14580	COG0583	DNA-binding transcription factor activity
ADU64_RS14585	COG1448	Aminotransferase
ADU64_RS14590	COG1418	mRNA catabolic process
ADU64_RS14615	COG1063	alcohol dehydrogenase
ADU64_RS14635	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ADU64_RS14645	COG0318	PFAM AMP-dependent synthetase and ligase
ADU64_RS14655	COG1522	sequence-specific DNA binding
ADU64_RS14660	COG3181	Tripartite tricarboxylate transporter family receptor
ADU64_RS14665	COG0307	riboflavin synthase, alpha
ADU64_RS14670	COG0154	amidase activity
ADU64_RS14690	COG2807	transmembrane transport
ADU64_RS14695	COG0590	tRNA wobble adenosine to inosine editing
ADU64_RS14705	COG0583	DNA-binding transcription factor activity
ADU64_RS14720	COG1902	pentaerythritol trinitrate reductase activity
ADU64_RS14740	COG0559	Belongs to the binding-protein-dependent transport system permease family
ADU64_RS14745	COG0251	oxidation-reduction process
ADU64_RS14750	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ADU64_RS14760	COG1414	Transcriptional regulator
ADU64_RS14765	COG1028	Short-chain dehydrogenase reductase Sdr
ADU64_RS14780	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ADU64_RS14795	COG1024	Enoyl-CoA hydratase
ADU64_RS14800	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ADU64_RS14805	COG0154	amidase activity
ADU64_RS14845	COG3909	cytochrome
ADU64_RS14850	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ADU64_RS14855	COG0625	glutathione transferase activity
ADU64_RS14860	COG0730	response to heat
ADU64_RS14865	COG0482	sulfurtransferase activity
ADU64_RS14870	COG0583	DNA-binding transcription factor activity
ADU64_RS14890	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ADU64_RS14915	COG2819	hydrolase of the alpha beta superfamily
ADU64_RS14920	COG0247	lactate metabolic process
ADU64_RS14925	COG0277	FAD linked oxidase domain protein
ADU64_RS14930	COG0277	FAD linked oxidase domain protein
ADU64_RS14935	COG0277	FAD linked oxidase domain protein
ADU64_RS14940	COG3210	domain, Protein
ADU64_RS14940	COG3064	Membrane
ADU64_RS14940	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
ADU64_RS14940	COG3064	Membrane
ADU64_RS14940	COG3210	domain, Protein
ADU64_RS14940	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
ADU64_RS14945	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ADU64_RS14950	COG0312	modulator of DNA gyrase
ADU64_RS14985	COG1666	GTP binding
ADU64_RS15030	COG3220	belongs to the UPF0276 family
ADU64_RS15050	COG0640	Transcriptional regulator
ADU64_RS15055	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ADU64_RS15060	COG1845	cytochrome c oxidase, subunit III
ADU64_RS15065	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ADU64_RS15075	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
ADU64_RS15110	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ADU64_RS15115	COG0583	DNA-binding transcription factor activity
ADU64_RS15145	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ADU64_RS15145	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ADU64_RS15160	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ADU64_RS15165	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ADU64_RS15175	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ADU64_RS15190	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
ADU64_RS15195	COG0316	Belongs to the HesB IscA family
ADU64_RS15205	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ADU64_RS15210	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ADU64_RS15215	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ADU64_RS15220	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ADU64_RS15225	COG0312	modulator of DNA gyrase
ADU64_RS15230	COG3028	Belongs to the UPF0307 family
ADU64_RS15245	COG1116	anion transmembrane transporter activity
ADU64_RS15250	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ADU64_RS15255	COG1335	isochorismatase
ADU64_RS15260	COG0346	lactoylglutathione lyase activity
ADU64_RS15265	COG0513	Belongs to the DEAD box helicase family
ADU64_RS15270	COG3069	C4-dicarboxylate transmembrane transporter activity
ADU64_RS15275	COG1802	Transcriptional regulator
ADU64_RS15290	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ADU64_RS15290	COG1042	CoA-binding domain protein
ADU64_RS15290	COG0045	succinate-CoA ligase (ADP-forming) activity
ADU64_RS15295	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ADU64_RS15310	COG1522	sequence-specific DNA binding
ADU64_RS15345	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ADU64_RS15350	COG1696	Membrane protein involved in D-alanine export
ADU64_RS15375	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ADU64_RS15385	COG2264	protein methyltransferase activity
ADU64_RS15390	COG0439	Biotin carboxylase
ADU64_RS15395	COG0511	ligase activity, forming carbon-carbon bonds
ADU64_RS15400	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ADU64_RS15405	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ADU64_RS15410	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ADU64_RS15415	COG3150	esterase
ADU64_RS15420	COG0557	exoribonuclease II activity
ADU64_RS15430	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ADU64_RS15450	COG1522	sequence-specific DNA binding
ADU64_RS15455	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ADU64_RS15460	COG1028	Short-chain dehydrogenase reductase Sdr
ADU64_RS15480	COG0653	protein targeting
ADU64_RS15485	COG0739	heme binding
ADU64_RS15495	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ADU64_RS15500	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ADU64_RS15510	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ADU64_RS15515	COG1181	Belongs to the D-alanine--D-alanine ligase family
ADU64_RS15520	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ADU64_RS15525	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ADU64_RS15535	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ADU64_RS15540	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ADU64_RS15545	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ADU64_RS15555	COG3116	cell division
ADU64_RS15560	COG0275	rRNA processing
ADU64_RS15565	COG2001	Belongs to the MraZ family
ADU64_RS15575	COG0488	(ABC) transporter
ADU64_RS15580	COG0418	dihydroorotase activity
ADU64_RS15585	COG1473	amidohydrolase
ADU64_RS15635	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ADU64_RS15640	COG4654	Cytochrome c, class I
ADU64_RS15645	COG0129	dihydroxy-acid dehydratase activity
ADU64_RS15650	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ADU64_RS15700	COG2084	Dehydrogenase
ADU64_RS15705	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ADU64_RS15720	COG2096	Adenosyltransferase
ADU64_RS15730	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ADU64_RS15735	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ADU64_RS15745	COG0523	cobalamin synthesis protein
ADU64_RS15750	COG0735	belongs to the Fur family
ADU64_RS15770	COG0803	Belongs to the bacterial solute-binding protein 9 family
ADU64_RS15780	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
ADU64_RS15790	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ADU64_RS15800	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ADU64_RS15805	COG1560	Kdo2-lipid A biosynthetic process
ADU64_RS15815	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ADU64_RS15830	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ADU64_RS15835	COG1950	PFAM Membrane protein of
ADU64_RS15850	COG0583	DNA-binding transcription factor activity
ADU64_RS15860	COG0477	Major facilitator Superfamily
ADU64_RS15875	COG0617	tRNA 3'-terminal CCA addition
ADU64_RS15885	COG0513	Belongs to the DEAD box helicase family
ADU64_RS15890	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ADU64_RS15905	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ADU64_RS15910	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
ADU64_RS15970	COG1280	lysine exporter protein (LysE YggA)
ADU64_RS15985	COG0405	Gamma-glutamyltransferase
ADU64_RS15995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ADU64_RS16025	COG1309	transcriptional regulator
ADU64_RS16035	COG3181	Tripartite tricarboxylate transporter family receptor
ADU64_RS16045	COG0745	RESPONSE REGULATOR receiver
ADU64_RS16110	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ADU64_RS16135	COG0582	viral genome integration into host DNA
ADU64_RS16140	COG0012	GTP binding
ADU64_RS16150	COG0193	aminoacyl-tRNA hydrolase activity
ADU64_RS16155	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ADU64_RS16160	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ADU64_RS16170	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ADU64_RS16175	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
ADU64_RS16185	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ADU64_RS16210	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
ADU64_RS16220	COG1368	sulfuric ester hydrolase activity
ADU64_RS16225	COG0642	Histidine kinase
ADU64_RS16230	COG0745	RESPONSE REGULATOR receiver
ADU64_RS16235	COG0277	FAD linked oxidase domain protein
ADU64_RS16250	COG0166	Belongs to the GPI family
ADU64_RS16255	COG0438	transferase activity, transferring glycosyl groups
ADU64_RS16260	COG0438	transferase activity, transferring glycosyl groups
ADU64_RS16275	COG0438	transferase activity, transferring glycosyl groups
ADU64_RS16290	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ADU64_RS16295	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ADU64_RS16300	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
ADU64_RS16310	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ADU64_RS16320	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ADU64_RS16325	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ADU64_RS16335	COG0747	negative chemotaxis
ADU64_RS16340	COG0601	transmembrane transport
ADU64_RS16345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ADU64_RS16365	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ADU64_RS16370	COG0830	nickel cation binding
ADU64_RS16380	COG0804	urea catabolic process
ADU64_RS16385	COG0832	Belongs to the urease beta subunit family
ADU64_RS16395	COG0831	urea catabolic process
ADU64_RS16400	COG0829	nickel cation binding
ADU64_RS16410	COG0633	Ferredoxin
ADU64_RS16425	COG2188	Transcriptional regulator
ADU64_RS16450	COG2719	SpoVR family
ADU64_RS16455	COG2718	Belongs to the UPF0229 family
ADU64_RS16470	COG1028	Short-chain dehydrogenase reductase Sdr
ADU64_RS16475	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ADU64_RS16490	COG1960	acyl-CoA dehydrogenase activity
ADU64_RS16535	COG0183	Belongs to the thiolase family
ADU64_RS16540	COG2030	dehydratase
ADU64_RS16595	COG0328	RNA-DNA hybrid ribonuclease activity
ADU64_RS16600	COG2226	methyltransferase
ADU64_RS16605	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ADU64_RS16610	COG1388	LysM domain
ADU64_RS16610	COG0741	lytic transglycosylase activity
ADU64_RS16630	COG2979	Protein of unknown function (DUF533)
ADU64_RS16665	COG1271	oxidase subunit
ADU64_RS16670	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ADU64_RS16675	COG0850	regulation of cytokinetic process
ADU64_RS16680	COG2894	cell division
ADU64_RS16685	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
ADU64_RS16705	COG0488	(ABC) transporter
ADU64_RS16720	COG0601	transmembrane transport
ADU64_RS16730	COG1215	transferase activity, transferring glycosyl groups
ADU64_RS16745	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ADU64_RS16755	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ADU64_RS16775	COG0318	PFAM AMP-dependent synthetase and ligase
ADU64_RS16780	COG2188	Transcriptional regulator
ADU64_RS16785	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ADU64_RS16790	COG2814	Major facilitator Superfamily
ADU64_RS16800	COG0259	pyridoxamine-phosphate oxidase activity
ADU64_RS16805	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ADU64_RS16820	COG0583	DNA-binding transcription factor activity
ADU64_RS16825	COG1960	acyl-CoA dehydrogenase activity
ADU64_RS16845	COG0134	indole-3-glycerol-phosphate synthase activity
ADU64_RS16850	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ADU64_RS16855	COG0512	Glutamine amidotransferase of anthranilate synthase
ADU64_RS16865	COG0546	phosphoglycolate phosphatase activity
ADU64_RS16870	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ADU64_RS16875	COG2967	ApaG domain
ADU64_RS16880	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ADU64_RS16885	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ADU64_RS16890	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ADU64_RS16895	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ADU64_RS16905	COG0037	tRNA processing
ADU64_RS16915	COG3634	alkyl hydroperoxide reductase activity
ADU64_RS16920	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ADU64_RS16925	COG1024	Enoyl-CoA hydratase
ADU64_RS16950	COG0356	it plays a direct role in the translocation of protons across the membrane
ADU64_RS16960	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ADU64_RS16965	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ADU64_RS16970	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ADU64_RS16975	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ADU64_RS16980	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ADU64_RS16985	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ADU64_RS16995	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ADU64_RS17000	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ADU64_RS17005	COG0210	DNA helicase
ADU64_RS17015	COG2195	Cleaves the N-terminal amino acid of tripeptides
ADU64_RS17025	COG4172	Belongs to the ABC transporter superfamily
ADU64_RS17030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ADU64_RS17035	COG0601	transmembrane transport
ADU64_RS17055	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ADU64_RS17060	COG1024	Enoyl-CoA hydratase
ADU64_RS17065	COG1024	Enoyl-CoA hydratase
ADU64_RS17090	COG1250	3-hydroxyacyl-CoA dehydrogenase
ADU64_RS17120	COG2132	Multicopper oxidase
ADU64_RS17130	COG1024	Enoyl-CoA hydratase
ADU64_RS17130	COG1250	3-hydroxyacyl-CoA dehydrogenase
ADU64_RS17140	COG1414	Transcriptional regulator
ADU64_RS17150	COG0154	amidase activity
ADU64_RS17180	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ADU64_RS17185	COG3568	Endonuclease Exonuclease Phosphatase
ADU64_RS17190	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ADU64_RS17225	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ADU64_RS17235	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ADU64_RS17250	COG1137	ATPase activity
ADU64_RS17255	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ADU64_RS17265	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
ADU64_RS17270	COG2010	Cytochrome c
ADU64_RS17270	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ADU64_RS17280	COG1660	Displays ATPase and GTPase activities
ADU64_RS17285	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ADU64_RS17320	COG3181	Tripartite tricarboxylate transporter family receptor
ADU64_RS17330	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ADU64_RS17335	COG2890	protein-(glutamine-N5) methyltransferase activity
ADU64_RS17340	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ADU64_RS17345	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ADU64_RS17395	COG1960	acyl-CoA dehydrogenase activity
ADU64_RS17405	COG0183	Belongs to the thiolase family
ADU64_RS17410	COG1522	sequence-specific DNA binding
ADU64_RS17415	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ADU64_RS17435	COG1024	Enoyl-CoA hydratase
ADU64_RS17450	COG0604	alcohol dehydrogenase
ADU64_RS17470	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ADU64_RS17480	COG1960	acyl-CoA dehydrogenase activity
ADU64_RS17485	COG1960	acyl-CoA dehydrogenase activity
ADU64_RS17490	COG0277	FAD linked oxidase domain protein
ADU64_RS17500	COG3181	Tripartite tricarboxylate transporter family receptor
ADU64_RS17525	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ADU64_RS17535	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ADU64_RS17540	COG3181	Tripartite tricarboxylate transporter family receptor
ADU64_RS17545	COG1960	acyl-CoA dehydrogenase activity
ADU64_RS17565	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ADU64_RS17570	COG1024	Enoyl-CoA hydratase
ADU64_RS17575	COG1960	acyl-CoA dehydrogenase activity
ADU64_RS17595	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ADU64_RS17600	COG0022	dehydrogenase e1 component
ADU64_RS17605	COG1024	Enoyl-CoA hydratase
ADU64_RS17610	COG0508	dehydrogenase complex catalyzes the overall conversion of
ADU64_RS17630	COG0683	leucine binding
ADU64_RS17635	COG0559	Belongs to the binding-protein-dependent transport system permease family
ADU64_RS17640	COG0411	ABC transporter
ADU64_RS17650	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ADU64_RS17665	COG3181	Tripartite tricarboxylate transporter family receptor
ADU64_RS17695	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ADU64_RS17700	COG0793	Belongs to the peptidase S41A family
ADU64_RS17705	COG4942	peptidase
ADU64_RS17710	COG0588	phosphoglycerate mutase activity
ADU64_RS17715	COG1054	Belongs to the UPF0176 family
ADU64_RS17720	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ADU64_RS17725	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
ADU64_RS17730	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ADU64_RS17735	COG3181	Tripartite tricarboxylate transporter family receptor
ADU64_RS17750	COG2226	methyltransferase
ADU64_RS17755	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ADU64_RS17770	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ADU64_RS17775	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ADU64_RS17800	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ADU64_RS17825	COG1335	isochorismatase
ADU64_RS17830	COG2309	aminopeptidase activity
ADU64_RS17835	COG0596	Alpha beta hydrolase
ADU64_RS17840	COG3473	Maleate cis-trans isomerase
ADU64_RS17850	COG2068	MobA-Related Protein
ADU64_RS17875	COG2204	response regulator
ADU64_RS17880	COG5000	phosphorelay sensor kinase activity
ADU64_RS17890	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ADU64_RS17890	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ADU64_RS17900	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
ADU64_RS17930	COG0583	DNA-binding transcription factor activity
ADU64_RS17945	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ADU64_RS17950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ADU64_RS17955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ADU64_RS17970	COG0758	DNA mediated transformation
ADU64_RS17975	COG1522	sequence-specific DNA binding
ADU64_RS17985	COG0242	peptide deformylase activity
ADU64_RS18000	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ADU64_RS18010	COG0546	phosphoglycolate phosphatase activity
ADU64_RS18030	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ADU64_RS18035	COG1942	4-Oxalocrotonate Tautomerase
ADU64_RS18040	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ADU64_RS18065	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ADU64_RS18085	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ADU64_RS18090	COG1024	Enoyl-CoA hydratase
ADU64_RS18095	COG1414	Transcriptional regulator
ADU64_RS18100	COG0318	PFAM AMP-dependent synthetase and ligase
ADU64_RS18105	COG3181	Tripartite tricarboxylate transporter family receptor
ADU64_RS18135	COG0583	DNA-binding transcription factor activity
ADU64_RS18150	COG3422	double-strand break repair
ADU64_RS18155	COG0330	HflC and HflK could
ADU64_RS18165	COG0251	oxidation-reduction process
ADU64_RS18210	COG3723	Recombinational DNA repair protein, rece pathway
ADU64_RS18245	COG0582	viral genome integration into host DNA
ADU64_RS18270	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ADU64_RS18280	COG0706	membrane insertase activity
ADU64_RS18285	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ADU64_RS18290	COG0594	ribonuclease P activity
ADU64_RS18295	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ADU64_RS18300	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ADU64_RS18315	COG1414	Transcriptional regulator
ADU64_RS18320	COG0154	amidase activity
ADU64_RS18335	COG1304	FMN binding
ADU64_RS18355	COG1960	acyl-CoA dehydrogenase activity
ADU64_RS18375	COG1960	acyl-CoA dehydrogenase activity
ADU64_RS18390	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ADU64_RS18405	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ADU64_RS18410	COG3181	Tripartite tricarboxylate transporter family receptor
ADU64_RS18420	COG2358	TRAP transporter, solute receptor (TAXI family
ADU64_RS18430	COG1629	transport
ADU64_RS18435	COG2922	Belongs to the Smg family
ADU64_RS18460	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ADU64_RS18465	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ADU64_RS18470	COG1028	Short-chain dehydrogenase reductase Sdr
ADU64_RS18475	COG1012	belongs to the aldehyde dehydrogenase family
ADU64_RS18485	COG0028	Belongs to the TPP enzyme family
ADU64_RS18490	COG1522	sequence-specific DNA binding
ADU64_RS18495	COG3781	membrane
ADU64_RS18505	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ADU64_RS18525	COG4206	TonB-dependent receptor
ADU64_RS18530	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ADU64_RS18535	COG2022	thiamine diphosphate biosynthetic process
ADU64_RS18540	COG0351	phosphomethylpyrimidine kinase
ADU64_RS18545	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ADU64_RS18560	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ADU64_RS18570	COG0628	permease
ADU64_RS18580	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ADU64_RS18590	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ADU64_RS18595	COG0049	tRNA binding
ADU64_RS18600	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ADU64_RS18605	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ADU64_RS18610	COG0051	transcription antitermination factor activity, RNA binding
ADU64_RS18615	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ADU64_RS18620	COG0088	Forms part of the polypeptide exit tunnel
ADU64_RS18625	COG0089	rRNA binding
ADU64_RS18630	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ADU64_RS18635	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ADU64_RS18640	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ADU64_RS18645	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ADU64_RS18650	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ADU64_RS18655	COG0255	Belongs to the universal ribosomal protein uL29 family
ADU64_RS18660	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ADU64_RS18680	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ADU64_RS18685	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ADU64_RS18690	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ADU64_RS18695	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ADU64_RS18700	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ADU64_RS18705	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ADU64_RS18710	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ADU64_RS18715	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ADU64_RS18720	COG1841	ribosomal large subunit assembly
ADU64_RS18725	COG0200	Binds to the 23S rRNA
ADU64_RS18730	COG0201	protein transport
ADU64_RS18735	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ADU64_RS18740	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ADU64_RS18745	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ADU64_RS18750	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ADU64_RS18755	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ADU64_RS18760	COG0202	RNA polymerase activity
ADU64_RS18765	COG0203	ribosomal protein L17
ADU64_RS18770	COG0537	adenosine 5'-monophosphoramidase activity
ADU64_RS18775	COG1324	tolerance protein
ADU64_RS18780	COG4232	protein-disulfide reductase activity
ADU64_RS18795	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ADU64_RS18805	COG1333	cytochrome c biogenesis protein
ADU64_RS18810	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ADU64_RS18825	COG1965	Belongs to the frataxin family
ADU64_RS18835	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ADU64_RS18840	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ADU64_RS18845	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ADU64_RS18860	COG2814	Major facilitator Superfamily
ADU64_RS18865	COG0629	single-stranded DNA binding
ADU64_RS18905	COG0402	S-adenosylhomocysteine deaminase activity
ADU64_RS18915	COG0438	transferase activity, transferring glycosyl groups
ADU64_RS18935	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ADU64_RS18960	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ADU64_RS18965	COG2186	Transcriptional regulator
ADU64_RS18985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ADU64_RS18990	COG1956	GAF domain-containing protein
ADU64_RS18995	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ADU64_RS19010	COG1652	LysM domain
ADU64_RS19025	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ADU64_RS19040	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ADU64_RS19070	COG3181	Tripartite tricarboxylate transporter family receptor
ADU64_RS19085	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ADU64_RS19100	COG1024	Enoyl-CoA hydratase
ADU64_RS19115	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ADU64_RS19120	COG1309	transcriptional regulator
ADU64_RS19125	COG2816	NAD+ diphosphatase activity
ADU64_RS19130	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ADU64_RS19215	COG2814	Major facilitator Superfamily
ADU64_RS19220	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ADU64_RS19240	COG1999	signal sequence binding
ADU64_RS19245	COG0109	protoheme IX farnesyltransferase activity
ADU64_RS19285	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ADU64_RS19305	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ADU64_RS19310	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ADU64_RS19320	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
ADU64_RS19325	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
ADU64_RS19335	COG0069	glutamate synthase activity
ADU64_RS19335	COG0067	glutamate synthase
ADU64_RS19335	COG0070	glutamate synthase
ADU64_RS19345	COG3047	cAMP biosynthetic process
ADU64_RS19355	COG1127	ABC transporter
ADU64_RS19360	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ADU64_RS19365	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ADU64_RS19370	COG2853	Lipoprotein
ADU64_RS19380	COG1131	(ABC) transporter
ADU64_RS19385	COG0842	Transport permease protein
ADU64_RS19395	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ADU64_RS19400	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ADU64_RS19405	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ADU64_RS19410	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ADU64_RS19415	COG0131	Imidazoleglycerol-phosphate dehydratase
ADU64_RS19420	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ADU64_RS19425	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ADU64_RS19430	COG0107	imidazoleglycerol-phosphate synthase activity
ADU64_RS19435	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ADU64_RS19440	COG0140	phosphoribosyl-ATP diphosphatase activity
ADU64_RS19445	COG0537	adenosine 5'-monophosphoramidase activity
ADU64_RS19450	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ADU64_RS19455	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ADU64_RS19470	COG3181	Tripartite tricarboxylate transporter family receptor
ADU64_RS19505	COG3702	type iv secretory pathway
ADU64_RS19510	COG3451	type IV secretory pathway VirB4
ADU64_RS19525	COG3736	Type IV secretory pathway, component VirB8
ADU64_RS19530	COG3504	Conjugal transfer protein
ADU64_RS19535	COG2948	multi-organism process
ADU64_RS19540	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
ADU64_RS19550	COG0697	spore germination
ADU64_RS19570	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ADU64_RS19575	COG0747	negative chemotaxis
ADU64_RS19580	COG0601	transmembrane transport
ADU64_RS19585	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ADU64_RS19590	COG0444	Belongs to the ABC transporter superfamily
ADU64_RS19600	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ADU64_RS19610	COG0494	nUDIX hydrolase
ADU64_RS19650	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
ADU64_RS19655	COG0237	dephospho-CoA kinase activity
ADU64_RS19660	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ADU64_RS19675	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ADU64_RS19680	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ADU64_RS19690	COG0477	Major facilitator Superfamily
ADU64_RS19695	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ADU64_RS19710	COG1126	abc transporter atp-binding protein
ADU64_RS19715	COG0765	amino acid transport
ADU64_RS19720	COG4597	amino acid ABC transporter
ADU64_RS19725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ADU64_RS19730	COG2884	Cell division ATP-binding protein ftsE
ADU64_RS19735	COG2177	Part of the ABC transporter FtsEX involved in
ADU64_RS19740	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ADU64_RS19750	COG1194	a g-specific adenine glycosylase
ADU64_RS19760	COG2226	methyltransferase
ADU64_RS19770	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ADU64_RS19775	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ADU64_RS19790	COG1024	Enoyl-CoA hydratase
ADU64_RS19810	COG1024	Enoyl-CoA hydratase
ADU64_RS19815	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ADU64_RS19820	COG3181	Tripartite tricarboxylate transporter family receptor
ADU64_RS19830	COG0753	catalase activity
ADU64_RS19835	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ADU64_RS19840	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ADU64_RS19850	COG2175	clavaminate synthase activity
ADU64_RS19855	COG1473	amidohydrolase
ADU64_RS19860	COG4608	Belongs to the ABC transporter superfamily
ADU64_RS19865	COG0444	Belongs to the ABC transporter superfamily
ADU64_RS19880	COG0747	negative chemotaxis
ADU64_RS19885	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ADU64_RS19920	COG0436	Aminotransferase
ADU64_RS19925	COG1278	Cold shock