locus-tag	class	description
CX036_RS00005	COG0445	tRNA wobble uridine modification
CX036_RS00010	COG0357	Ribosomal RNA small subunit methyltransferase G
CX036_RS00015	COG1192	Involved in chromosome partitioning
CX036_RS00025	COG1475	DNA binding
CX036_RS00050	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CX036_RS00060	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CX036_RS00070	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CX036_RS00075	COG0081	regulation of translation
CX036_RS00080	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CX036_RS00085	COG0222	ribosome binding
CX036_RS00090	COG0085	RNA polymerase activity
CX036_RS00095	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CX036_RS00135	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX036_RS00160	COG1024	Enoyl-CoA hydratase
CX036_RS00180	COG0752	glycyl-tRNA synthetase alpha subunit
CX036_RS00185	COG0751	glycine-tRNA ligase activity
CX036_RS00190	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CX036_RS00195	COG0204	Acyl-transferase
CX036_RS00210	COG0242	peptide deformylase activity
CX036_RS00250	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CX036_RS00255	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CX036_RS00255	COG2813	Specifically methylates the guanine in position
CX036_RS00270	COG2223	nitrite transmembrane transporter activity
CX036_RS00280	COG1794	racemase activity, acting on amino acids and derivatives
CX036_RS00285	COG1126	abc transporter atp-binding protein
CX036_RS00290	COG0765	amino acid transport
CX036_RS00295	COG0765	amino acid transport
CX036_RS00300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CX036_RS00365	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CX036_RS00395	COG0326	Molecular chaperone. Has ATPase activity
CX036_RS00400	COG0625	glutathione transferase activity
CX036_RS00415	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CX036_RS00420	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CX036_RS00450	COG0438	transferase activity, transferring glycosyl groups
CX036_RS00455	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CX036_RS00460	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CX036_RS00490	COG0859	PFAM glycosyl transferase family 9
CX036_RS00505	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CX036_RS00515	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CX036_RS00520	COG1127	ABC transporter
CX036_RS00540	COG1686	Belongs to the peptidase S11 family
CX036_RS00550	COG2921	Belongs to the UPF0250 family
CX036_RS00555	COG0321	lipoyl(octanoyl) transferase activity
CX036_RS00560	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CX036_RS00595	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CX036_RS00605	COG0018	arginyl-trna synthetase
CX036_RS00625	COG0395	ABC-type sugar transport system, permease component
CX036_RS00630	COG1175	transmembrane transport
CX036_RS00635	COG1653	transport
CX036_RS00640	COG3842	ATPase activity
CX036_RS00645	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CX036_RS00655	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CX036_RS00675	COG1609	Transcriptional regulator
CX036_RS00685	COG0154	amidase activity
CX036_RS00690	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CX036_RS00700	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CX036_RS00710	COG0583	DNA-binding transcription factor activity
CX036_RS00730	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CX036_RS00745	COG1802	Transcriptional regulator
CX036_RS00760	COG1024	Enoyl-CoA hydratase
CX036_RS00770	COG3181	Tripartite tricarboxylate transporter family receptor
CX036_RS00785	COG1984	allophanate hydrolase subunit 2
CX036_RS00790	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CX036_RS00800	COG0583	DNA-binding transcription factor activity
CX036_RS00805	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CX036_RS00815	COG5002	protein histidine kinase activity
CX036_RS00825	COG5002	protein histidine kinase activity
CX036_RS00830	COG0745	RESPONSE REGULATOR receiver
CX036_RS00835	COG2226	methyltransferase
CX036_RS00850	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CX036_RS00870	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CX036_RS00880	COG0513	Belongs to the DEAD box helicase family
CX036_RS00885	COG1280	lysine exporter protein (LysE YggA)
CX036_RS00890	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CX036_RS00930	COG1054	Belongs to the UPF0176 family
CX036_RS00935	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CX036_RS00935	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CX036_RS00945	COG0489	protein tyrosine kinase activity
CX036_RS00960	COG0717	Belongs to the dCTP deaminase family
CX036_RS00990	COG2081	HI0933 family
CX036_RS01000	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CX036_RS01010	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CX036_RS01015	COG0509	glycine decarboxylation via glycine cleavage system
CX036_RS01020	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CX036_RS01020	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CX036_RS01060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CX036_RS01075	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CX036_RS01085	COG1414	Transcriptional regulator
CX036_RS01090	COG1028	Short-chain dehydrogenase reductase Sdr
CX036_RS01095	COG2031	fatty acid transporter
CX036_RS01100	COG1250	3-hydroxyacyl-CoA dehydrogenase
CX036_RS01110	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CX036_RS01115	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CX036_RS01125	COG4257	antibiotic catabolic process
CX036_RS01150	COG1012	belongs to the aldehyde dehydrogenase family
CX036_RS01155	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CX036_RS01160	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CX036_RS01190	COG1028	Short-chain dehydrogenase reductase Sdr
CX036_RS01200	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CX036_RS01210	COG2188	Transcriptional regulator
CX036_RS01215	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CX036_RS01240	COG0617	tRNA 3'-terminal CCA addition
CX036_RS01255	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CX036_RS01260	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CX036_RS01265	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CX036_RS01270	COG0586	Pfam SNARE associated Golgi protein
CX036_RS01275	COG0860	N-Acetylmuramoyl-L-alanine amidase
CX036_RS01280	COG0802	atpase or kinase
CX036_RS01285	COG0114	fumarate hydratase activity
CX036_RS01295	COG3181	Tripartite tricarboxylate transporter family receptor
CX036_RS01305	COG0405	Gamma-glutamyltransferase
CX036_RS01310	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX036_RS01345	COG1294	oxidase, subunit
CX036_RS01355	COG4988	ABC transporter
CX036_RS01360	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CX036_RS01410	COG2969	positive regulation of protein catabolic process
CX036_RS01415	COG0625	glutathione transferase activity
CX036_RS01420	COG2857	Cytochrome c1
CX036_RS01425	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CX036_RS01430	COG0723	plastoquinol--plastocyanin reductase activity
CX036_RS01435	COG1970	mechanosensitive ion channel activity
CX036_RS01440	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CX036_RS01455	COG2808	Putative FMN-binding domain
CX036_RS01460	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CX036_RS01465	COG0747	negative chemotaxis
CX036_RS01470	COG0657	acetylesterase activity
CX036_RS01480	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CX036_RS01485	COG2207	Transcriptional regulator
CX036_RS01490	COG0129	dihydroxy-acid dehydratase activity
CX036_RS01495	COG2814	Major facilitator Superfamily
CX036_RS01500	COG0583	DNA-binding transcription factor activity
CX036_RS01510	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
CX036_RS01580	COG1024	Enoyl-CoA hydratase
CX036_RS01585	COG1960	acyl-CoA dehydrogenase activity
CX036_RS01610	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CX036_RS01615	COG0352	thiamine-phosphate diphosphorylase activity
CX036_RS01630	COG1678	Uncharacterized ACR, COG1678
CX036_RS01635	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CX036_RS01640	COG0540	Belongs to the ATCase OTCase family
CX036_RS01655	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CX036_RS01665	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CX036_RS01700	COG1234	tRNA 3'-trailer cleavage
CX036_RS01720	COG3064	Membrane
CX036_RS01750	COG1683	Conserved Protein
CX036_RS01755	COG1120	ATPase activity
CX036_RS01760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CX036_RS01765	COG4558	Periplasmic binding protein
CX036_RS01770	COG3720	iron ion transport
CX036_RS01780	COG3712	iron ion homeostasis
CX036_RS01785	COG1595	DNA-templated transcription, initiation
CX036_RS01820	COG1802	Transcriptional regulator
CX036_RS01830	COG3069	C4-dicarboxylate transmembrane transporter activity
CX036_RS01840	COG1012	belongs to the aldehyde dehydrogenase family
CX036_RS01875	COG2860	membrane
CX036_RS01880	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CX036_RS01885	COG0708	Exodeoxyribonuclease III
CX036_RS01890	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CX036_RS01895	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CX036_RS01900	COG0154	amidase activity
CX036_RS01905	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CX036_RS01910	COG1077	Cell shape determining protein MreB Mrl
CX036_RS01915	COG1792	Involved in formation and maintenance of cell shape
CX036_RS01925	COG0768	penicillin binding
CX036_RS01930	COG0772	Belongs to the SEDS family
CX036_RS01935	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CX036_RS01940	COG0471	metal ion transport
CX036_RS01945	COG1309	transcriptional regulator
CX036_RS01955	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CX036_RS01970	COG2823	Periplasmic or secreted lipoprotein
CX036_RS01975	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CX036_RS01990	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CX036_RS02010	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX036_RS02020	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX036_RS02040	COG0492	ferredoxin-NADP+ reductase activity
CX036_RS02050	COG3181	Tripartite tricarboxylate transporter family receptor
CX036_RS02055	COG1024	Enoyl-CoA hydratase
CX036_RS02055	COG1250	3-hydroxyacyl-CoA dehydrogenase
CX036_RS02060	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX036_RS02065	COG0028	Belongs to the TPP enzyme family
CX036_RS02090	COG3181	Tripartite tricarboxylate transporter family receptor
CX036_RS02105	COG0697	spore germination
CX036_RS02135	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CX036_RS02140	COG0463	Glycosyl transferase, family 2
CX036_RS02155	COG0786	glutamate:sodium symporter activity
CX036_RS02165	COG2031	fatty acid transporter
CX036_RS02180	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CX036_RS02195	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CX036_RS02210	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CX036_RS02220	COG1285	pathogenesis
CX036_RS02225	COG1253	flavin adenine dinucleotide binding
CX036_RS02230	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX036_RS02235	COG1024	Enoyl-CoA hydratase
CX036_RS02240	COG3181	Tripartite tricarboxylate transporter family receptor
CX036_RS02245	COG0583	DNA-binding transcription factor activity
CX036_RS02250	COG1960	acyl-CoA dehydrogenase activity
CX036_RS02260	COG0183	Belongs to the thiolase family
CX036_RS02280	COG0583	DNA-binding transcription factor activity
CX036_RS02290	COG1278	Cold shock
CX036_RS02300	COG1802	Transcriptional regulator
CX036_RS02305	COG1012	belongs to the aldehyde dehydrogenase family
CX036_RS02310	COG2031	fatty acid transporter
CX036_RS02315	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CX036_RS02315	COG1017	nitric oxide dioxygenase activity
CX036_RS02320	COG0251	oxidation-reduction process
CX036_RS02340	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX036_RS02350	COG0583	DNA-binding transcription factor activity
CX036_RS02355	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX036_RS02370	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CX036_RS02375	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CX036_RS02380	COG0546	phosphoglycolate phosphatase activity
CX036_RS02390	COG1530	ribonuclease E activity
CX036_RS02410	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CX036_RS02415	COG0159	tryptophan synthase activity
CX036_RS02420	COG0133	tryptophan synthase activity
CX036_RS02430	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CX036_RS02435	COG3228	Belongs to the MtfA family
CX036_RS02445	COG0251	oxidation-reduction process
CX036_RS02450	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CX036_RS02455	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CX036_RS02470	COG2878	Part of a membrane complex involved in electron transport
CX036_RS02475	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CX036_RS02510	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CX036_RS02530	COG1268	BioY protein
CX036_RS02535	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CX036_RS02540	COG1122	ATPase activity
CX036_RS02545	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CX036_RS02560	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CX036_RS02565	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CX036_RS02575	COG1196	nuclear chromosome segregation
CX036_RS02580	COG0477	Major facilitator Superfamily
CX036_RS02585	COG1573	uracil-dna glycosylase
CX036_RS02590	COG1214	PFAM Peptidase M22, glycoprotease
CX036_RS02610	COG0450	alkyl hydroperoxide reductase
CX036_RS02615	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CX036_RS02625	COG2223	nitrite transmembrane transporter activity
CX036_RS02635	COG2186	Transcriptional regulator
CX036_RS02655	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CX036_RS02665	COG0583	DNA-binding transcription factor activity
CX036_RS02675	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CX036_RS02680	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CX036_RS02685	COG0137	argininosuccinate synthase activity
CX036_RS02690	COG3158	transport of potassium into the cell
CX036_RS02695	COG0642	Histidine kinase
CX036_RS02725	COG0776	regulation of translation
CX036_RS02730	COG3128	pkhd-type hydroxylase
CX036_RS02740	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CX036_RS02745	COG0557	exoribonuclease II activity
CX036_RS02770	COG0679	Auxin Efflux Carrier
CX036_RS02775	COG2391	methyltransferase activity
CX036_RS02780	COG0069	glutamate synthase activity
CX036_RS02790	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CX036_RS02800	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
CX036_RS02840	COG3706	GGDEF domain
CX036_RS02865	COG1053	succinate dehydrogenase
CX036_RS02870	COG0583	DNA-binding transcription factor activity
CX036_RS02885	COG1053	succinate dehydrogenase
CX036_RS02905	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CX036_RS02910	COG0459	protein refolding
CX036_RS02915	COG3468	outer membrane autotransporter barrel domain protein
CX036_RS02930	COG1252	NADH dehydrogenase
CX036_RS02935	COG0284	orotidine-5'-phosphate decarboxylase activity
CX036_RS02940	COG1058	Belongs to the CinA family
CX036_RS02940	COG1546	Belongs to the CinA family
CX036_RS02945	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CX036_RS02955	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CX036_RS02960	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CX036_RS03000	COG3639	organic phosphonate transmembrane transporter activity
CX036_RS03005	COG3639	organic phosphonate transmembrane transporter activity
CX036_RS03025	COG0742	ribosomal rna small subunit methyltransferase
CX036_RS03030	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CX036_RS03035	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CX036_RS03040	COG3135	benzoate transporter
CX036_RS03055	COG0640	Transcriptional regulator
CX036_RS03085	COG4172	Belongs to the ABC transporter superfamily
CX036_RS03090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CX036_RS03095	COG0601	transmembrane transport
CX036_RS03105	COG0280	phosphate acetyltransferase
CX036_RS03105	COG0281	malic enzyme
CX036_RS03165	COG0583	DNA-binding transcription factor activity
CX036_RS03180	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CX036_RS03185	COG0167	dihydroorotate dehydrogenase activity
CX036_RS03205	COG1414	Transcriptional regulator
CX036_RS03210	COG1058	Belongs to the CinA family
CX036_RS03210	COG1546	Belongs to the CinA family
CX036_RS03230	COG0513	Belongs to the DEAD box helicase family
CX036_RS03260	COG0429	hydrolase of the alpha beta-hydrolase fold
CX036_RS03265	COG4783	chaperone-mediated protein folding
CX036_RS03280	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CX036_RS03305	COG0006	proline dipeptidase activity
CX036_RS03315	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CX036_RS03335	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CX036_RS03340	COG0632	four-way junction helicase activity
CX036_RS03355	COG2255	four-way junction helicase activity
CX036_RS03360	COG0514	ATP-dependent DNA helicase (RecQ)
CX036_RS03375	COG0288	reversible hydration of carbon dioxide
CX036_RS03380	COG0154	amidase activity
CX036_RS03390	COG4211	Belongs to the binding-protein-dependent transport system permease family
CX036_RS03420	COG1464	Belongs to the NlpA lipoprotein family
CX036_RS03560	COG1196	nuclear chromosome segregation
CX036_RS03635	COG2135	peptidase activity
CX036_RS03650	COG0494	nUDIX hydrolase
CX036_RS03655	COG0442	prolyl-tRNA aminoacylation
CX036_RS03660	COG0824	Thioesterase
CX036_RS03665	COG0811	peptide transport
CX036_RS03670	COG0848	biopolymer transport protein
CX036_RS03680	COG0823	Involved in the tonB-independent uptake of proteins
CX036_RS03695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CX036_RS03700	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CX036_RS03735	COG0700	Nucleoside recognition
CX036_RS03740	COG0469	pyruvate kinase activity
CX036_RS03745	COG1929	Belongs to the glycerate kinase type-1 family
CX036_RS03750	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CX036_RS03755	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CX036_RS03760	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CX036_RS03770	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CX036_RS03780	COG2154	pterin-4-alpha-carbinolamine dehydratase
CX036_RS03805	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CX036_RS03810	COG0154	amidase activity
CX036_RS03820	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CX036_RS03825	COG0601	transmembrane transport
CX036_RS03830	COG0747	negative chemotaxis
CX036_RS03850	COG0019	diaminopimelate decarboxylase activity
CX036_RS03865	COG2353	YceI-like domain
CX036_RS03870	COG4774	siderophore transport
CX036_RS03875	COG3712	iron ion homeostasis
CX036_RS03920	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CX036_RS03925	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CX036_RS03930	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CX036_RS03935	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CX036_RS03945	COG0142	geranyltranstransferase activity
CX036_RS03955	COG0583	DNA-binding transcription factor activity
CX036_RS03965	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
CX036_RS03970	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CX036_RS03990	COG2994	toxin metabolic process
CX036_RS04000	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CX036_RS04005	COG2274	protein secretion by the type I secretion system
CX036_RS04010	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CX036_RS04015	COG1538	Outer membrane efflux protein
CX036_RS04040	COG0765	amino acid transport
CX036_RS04045	COG1126	abc transporter atp-binding protein
CX036_RS04065	COG1028	Short-chain dehydrogenase reductase Sdr
CX036_RS04075	COG1802	Transcriptional regulator
CX036_RS04085	COG1802	Transcriptional regulator
CX036_RS04095	COG0318	PFAM AMP-dependent synthetase and ligase
CX036_RS04105	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CX036_RS04125	COG0028	Belongs to the TPP enzyme family
CX036_RS04145	COG0308	aminopeptidase N
CX036_RS04150	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CX036_RS04165	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CX036_RS04170	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CX036_RS04175	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CX036_RS04180	COG0560	Phosphoserine phosphatase
CX036_RS04185	COG0583	DNA-binding transcription factor activity
CX036_RS04190	COG3181	Tripartite tricarboxylate transporter family receptor
CX036_RS04195	COG0028	Belongs to the TPP enzyme family
CX036_RS04210	COG4774	siderophore transport
CX036_RS04215	COG4774	siderophore transport
CX036_RS04225	COG1007	ATP synthesis coupled electron transport
CX036_RS04240	COG0713	ATP synthesis coupled electron transport
CX036_RS04250	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CX036_RS04255	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CX036_RS04260	COG1034	ATP synthesis coupled electron transport
CX036_RS04270	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CX036_RS04275	COG0649	NAD binding
CX036_RS04280	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CX036_RS04285	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CX036_RS04290	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CX036_RS04295	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CX036_RS04325	COG0671	phosphoesterase, PA-phosphatase related
CX036_RS04335	COG1597	lipid kinase activity
CX036_RS04340	COG0583	DNA-binding transcription factor activity
CX036_RS04345	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CX036_RS04355	COG1733	regulation of RNA biosynthetic process
CX036_RS04360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CX036_RS04365	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CX036_RS04380	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
CX036_RS04400	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CX036_RS04420	COG3608	succinylglutamate desuccinylase aspartoacylase
CX036_RS04425	COG0626	cystathionine gamma-synthase activity
CX036_RS04430	COG0583	DNA-binding transcription factor activity
CX036_RS04465	COG3799	methylaspartate ammonia-lyase activity
CX036_RS04475	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CX036_RS04485	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CX036_RS04490	COG0149	triose-phosphate isomerase activity
CX036_RS04510	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CX036_RS04525	COG1185	polyribonucleotide nucleotidyltransferase activity
CX036_RS04530	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CX036_RS04545	COG1183	phosphatidylcholine synthase activity
CX036_RS04550	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CX036_RS04555	COG0440	acetolactate synthase activity
CX036_RS04560	COG0028	Belongs to the TPP enzyme family
CX036_RS04575	COG5265	(ABC) transporter
CX036_RS04580	COG0500	methyltransferase
CX036_RS04600	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CX036_RS04620	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CX036_RS04630	COG0511	ligase activity, forming carbon-carbon bonds
CX036_RS04655	COG2188	Transcriptional regulator
CX036_RS04660	COG0439	Biotin carboxylase
CX036_RS04710	COG5265	(ABC) transporter
CX036_RS04720	COG0667	Aldo Keto reductase
CX036_RS04735	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CX036_RS04775	COG0583	DNA-binding transcription factor activity
CX036_RS04810	COG2814	Major facilitator Superfamily
CX036_RS04820	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CX036_RS04835	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CX036_RS04845	COG0287	Prephenate dehydrogenase
CX036_RS04850	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CX036_RS04855	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CX036_RS04875	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CX036_RS04880	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CX036_RS04885	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CX036_RS04890	COG1596	polysaccharide export
CX036_RS04890	COG1555	photosystem II stabilization
CX036_RS04905	COG2951	lytic endotransglycosylase activity
CX036_RS04910	COG0123	including yeast histone deacetylase and acetoin utilization protein
CX036_RS04925	COG1960	acyl-CoA dehydrogenase activity
CX036_RS04930	COG0450	alkyl hydroperoxide reductase
CX036_RS04950	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CX036_RS04985	COG0335	large ribosomal subunit rRNA binding
CX036_RS05000	COG0667	Aldo Keto reductase
CX036_RS05015	COG3161	chorismate lyase activity
CX036_RS05020	COG1187	pseudouridine synthase activity
CX036_RS05050	COG1999	signal sequence binding
CX036_RS05055	COG0339	signal peptide processing
CX036_RS05060	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CX036_RS05065	COG4566	intracellular signal transduction
CX036_RS05075	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CX036_RS05080	COG0508	dehydrogenase complex catalyzes the overall conversion of
CX036_RS05085	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CX036_RS05090	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CX036_RS05100	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CX036_RS05105	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CX036_RS05110	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CX036_RS05115	COG0126	phosphoglycerate kinase activity
CX036_RS05120	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CX036_RS05125	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CX036_RS05140	COG0625	glutathione transferase activity
CX036_RS05170	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CX036_RS05180	COG0521	Mo-molybdopterin cofactor biosynthetic process
CX036_RS05190	COG0739	heme binding
CX036_RS05200	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CX036_RS05235	COG0745	RESPONSE REGULATOR receiver
CX036_RS05250	COG0840	transmembrane signaling receptor activity
CX036_RS05260	COG2201	protein-glutamate methylesterase activity
CX036_RS05265	COG0745	RESPONSE REGULATOR receiver
CX036_RS05270	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CX036_RS05295	COG0667	Aldo Keto reductase
CX036_RS05305	COG4535	Mg2 and Co2 transporter CorC
CX036_RS05310	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CX036_RS05315	COG1702	phosphate starvation-inducible protein PhoH
CX036_RS05320	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CX036_RS05335	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CX036_RS05340	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CX036_RS05345	COG1862	Preprotein translocase
CX036_RS05350	COG0343	queuine tRNA-ribosyltransferase activity
CX036_RS05355	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CX036_RS05360	COG2027	D-alanyl-D-alanine carboxypeptidase
CX036_RS05365	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CX036_RS05375	COG3468	outer membrane autotransporter barrel domain protein
CX036_RS05380	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CX036_RS05380	COG1648	precorrin-2 dehydrogenase activity
CX036_RS05405	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CX036_RS05410	COG0741	lytic transglycosylase activity
CX036_RS05420	COG0436	Aminotransferase
CX036_RS05430	COG0280	phosphate acetyltransferase
CX036_RS05430	COG0281	malic enzyme
CX036_RS05440	COG2732	(Barnase) inhibitor
CX036_RS05455	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CX036_RS05480	COG0248	Ppx GppA phosphatase
CX036_RS05490	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CX036_RS05500	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CX036_RS05505	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CX036_RS05510	COG1534	Rna-binding protein
CX036_RS05540	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CX036_RS05555	COG1295	ribonuclease BN
CX036_RS05565	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CX036_RS05570	COG0745	RESPONSE REGULATOR receiver
CX036_RS05575	COG2205	protein histidine kinase activity
CX036_RS05610	COG1022	Amp-dependent synthetase and ligase
CX036_RS05625	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CX036_RS05630	COG1028	Short-chain dehydrogenase reductase Sdr
CX036_RS05640	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CX036_RS05655	COG1136	(ABC) transporter
CX036_RS05660	COG0084	hydrolase, TatD family'
CX036_RS05685	COG0658	competence protein
CX036_RS05685	COG2333	competence protein COMEC
CX036_RS05695	COG0613	PHP domain protein
CX036_RS05715	COG3539	Fimbrial protein
CX036_RS05720	COG0281	malic enzyme
CX036_RS05720	COG0280	phosphate acetyltransferase
CX036_RS05730	COG1522	sequence-specific DNA binding
CX036_RS05740	COG0567	Dehydrogenase, E1 component
CX036_RS05745	COG0508	dehydrogenase complex catalyzes the overall conversion of
CX036_RS05750	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CX036_RS05755	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CX036_RS05760	COG1028	Short-chain dehydrogenase reductase Sdr
CX036_RS05765	COG0583	DNA-binding transcription factor activity
CX036_RS05775	COG3181	Tripartite tricarboxylate transporter family receptor
CX036_RS05800	COG0180	Tryptophanyl-tRNA synthetase
CX036_RS05805	COG2183	response to ionizing radiation
CX036_RS05810	COG1199	ATP-dependent helicase activity
CX036_RS05820	COG0564	pseudouridine synthase activity
CX036_RS05830	COG3243	poly(R)-hydroxyalkanoic acid synthase
CX036_RS05835	COG1028	Short-chain dehydrogenase reductase Sdr
CX036_RS05840	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
CX036_RS05855	COG0672	)-iron permease
CX036_RS05895	COG0583	DNA-binding transcription factor activity
CX036_RS05905	COG2814	Major facilitator Superfamily
CX036_RS05920	COG1619	proteins homologs of microcin C7 resistance protein MccF
CX036_RS05935	COG2084	Dehydrogenase
CX036_RS05940	COG3181	Tripartite tricarboxylate transporter family receptor
CX036_RS05965	COG2988	succinylglutamate desuccinylase activity
CX036_RS05995	COG0765	amino acid transport
CX036_RS06000	COG0765	amino acid transport
CX036_RS06005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CX036_RS06040	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CX036_RS06045	COG1595	DNA-templated transcription, initiation
CX036_RS06055	COG3530	Putative quorum-sensing-regulated virulence factor
CX036_RS06060	COG0494	nUDIX hydrolase
CX036_RS06075	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CX036_RS06080	COG0542	response to heat
CX036_RS06100	COG3468	outer membrane autotransporter barrel domain protein
CX036_RS06110	COG5441	Belongs to the UPF0261 family
CX036_RS06115	COG5564	TIM-barrel signal transduction protein
CX036_RS06130	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CX036_RS06145	COG1477	protein flavinylation
CX036_RS06165	COG1131	(ABC) transporter
CX036_RS06170	COG0842	Transport permease protein
CX036_RS06180	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CX036_RS06185	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CX036_RS06185	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CX036_RS06190	COG1562	ergosterol biosynthetic process
CX036_RS06195	COG1562	ergosterol biosynthetic process
CX036_RS06200	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CX036_RS06205	COG1028	Short-chain dehydrogenase reductase Sdr
CX036_RS06225	COG2304	oxidoreductase activity
CX036_RS06245	COG0534	Mate efflux family protein
CX036_RS06255	COG0254	rRNA binding
CX036_RS06260	COG3483	tryptophan 2,3-dioxygenase activity
CX036_RS06265	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CX036_RS06270	COG2003	Belongs to the UPF0758 family
CX036_RS06275	COG1047	Peptidyl-prolyl cis-trans
CX036_RS06280	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CX036_RS06285	COG0625	glutathione transferase activity
CX036_RS06305	COG0523	cobalamin synthesis protein
CX036_RS06315	COG0583	DNA-binding transcription factor activity
CX036_RS06325	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CX036_RS06330	COG1187	pseudouridine synthase activity
CX036_RS06335	COG0779	Required for maturation of 30S ribosomal subunits
CX036_RS06340	COG0195	Participates in both transcription termination and antitermination
CX036_RS06340	COG2251	uridine kinase activity
CX036_RS06345	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CX036_RS06350	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CX036_RS06355	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CX036_RS06375	COG1611	Belongs to the LOG family
CX036_RS06390	COG0412	Dienelactone hydrolase
CX036_RS06395	COG1283	sodium-dependent phosphate transmembrane transporter activity
CX036_RS06400	COG1760	l-serine dehydratase
CX036_RS06405	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CX036_RS06410	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CX036_RS06420	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CX036_RS06445	COG2311	Membrane
CX036_RS06470	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CX036_RS06490	COG0559	Belongs to the binding-protein-dependent transport system permease family
CX036_RS06510	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CX036_RS06520	COG1653	transport
CX036_RS06525	COG1175	transmembrane transport
CX036_RS06530	COG0395	ABC-type sugar transport system, permease component
CX036_RS06535	COG3842	ATPase activity
CX036_RS06565	COG2363	Small membrane protein
CX036_RS06580	COG1464	Belongs to the NlpA lipoprotein family
CX036_RS06590	COG0688	phosphatidylethanolamine metabolic process
CX036_RS06605	COG0095	Lipoate-protein ligase
CX036_RS06620	COG0625	glutathione transferase activity
CX036_RS06625	COG0386	Belongs to the glutathione peroxidase family
CX036_RS06645	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX036_RS06675	COG2259	Doxx family
CX036_RS06690	COG0667	Aldo Keto reductase
CX036_RS06720	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CX036_RS06740	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CX036_RS06750	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CX036_RS06800	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CX036_RS06805	COG3568	Endonuclease Exonuclease Phosphatase
CX036_RS06815	COG1695	Transcriptional regulator
CX036_RS06835	COG0583	DNA-binding transcription factor activity
CX036_RS06850	COG1802	Transcriptional regulator
CX036_RS06860	COG3181	Tripartite tricarboxylate transporter family receptor
CX036_RS06870	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX036_RS06885	COG0066	3-isopropylmalate dehydratase activity
CX036_RS06895	COG3181	Tripartite tricarboxylate transporter family receptor
CX036_RS06900	COG4948	Mandelate Racemase Muconate Lactonizing
CX036_RS06915	COG1126	abc transporter atp-binding protein
CX036_RS06920	COG0765	amino acid transport
CX036_RS06925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CX036_RS06965	COG1815	bacterial-type flagellum-dependent cell motility
CX036_RS06970	COG1558	bacterial-type flagellum-dependent cell motility
CX036_RS06980	COG1749	Flagellar hook protein flgE
CX036_RS06995	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CX036_RS07000	COG1706	bacterial-type flagellum-dependent cell motility
CX036_RS07010	COG1256	bacterial-type flagellum assembly
CX036_RS07020	COG0840	transmembrane signaling receptor activity
CX036_RS07025	COG0840	transmembrane signaling receptor activity
CX036_RS07030	COG0840	transmembrane signaling receptor activity
CX036_RS07050	COG1338	Plays a role in the flagellum-specific transport system
CX036_RS07070	COG1580	Controls the rotational direction of flagella during chemotaxis
CX036_RS07095	COG1157	protein secretion by the type III secretion system
CX036_RS07100	COG1317	bacterial-type flagellum organization
CX036_RS07105	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CX036_RS07115	COG1677	Flagellar hook-basal body complex protein FliE
CX036_RS07125	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CX036_RS07160	COG0285	dihydrofolate synthase activity
CX036_RS07190	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CX036_RS07195	COG0024	Methionine aminopeptidase
CX036_RS07200	COG0052	Belongs to the universal ribosomal protein uS2 family
CX036_RS07205	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CX036_RS07210	COG0528	UMP kinase activity
CX036_RS07215	COG0233	cytoplasmic translational termination
CX036_RS07220	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CX036_RS07230	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CX036_RS07235	COG0750	zinc metalloprotease
CX036_RS07240	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CX036_RS07245	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CX036_RS07250	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CX036_RS07255	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CX036_RS07265	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CX036_RS07270	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CX036_RS07275	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CX036_RS07280	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CX036_RS07290	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CX036_RS07290	COG0519	Catalyzes the synthesis of GMP from XMP
CX036_RS07305	COG0330	HflC and HflK could
CX036_RS07310	COG3706	GGDEF domain
CX036_RS07315	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CX036_RS07325	COG2867	negative regulation of translational initiation
CX036_RS07335	COG1960	acyl-CoA dehydrogenase activity
CX036_RS07340	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CX036_RS07375	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CX036_RS07380	COG0505	Belongs to the CarA family
CX036_RS07385	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CX036_RS07395	COG0406	alpha-ribazole phosphatase activity
CX036_RS07405	COG3842	ATPase activity
CX036_RS07425	COG5001	Diguanylate cyclase
CX036_RS07430	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CX036_RS07440	COG1763	Mo-molybdopterin cofactor biosynthetic process
CX036_RS07445	COG0303	'Molybdopterin
CX036_RS07450	COG0746	molybdenum cofactor guanylyltransferase activity
CX036_RS07455	COG0489	protein tyrosine kinase activity
CX036_RS07485	COG0243	molybdopterin cofactor binding
CX036_RS07485	COG3383	formate dehydrogenase (NAD+) activity
CX036_RS07520	COG1122	ATPase activity
CX036_RS07530	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CX036_RS07535	COG0066	3-isopropylmalate dehydratase activity
CX036_RS07540	COG0473	3-isopropylmalate dehydrogenase activity
CX036_RS07545	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CX036_RS07555	COG0101	tRNA pseudouridine synthase activity
CX036_RS07560	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CX036_RS07575	COG0135	phosphoribosylanthranilate isomerase activity
CX036_RS07590	COG3022	response to hydroperoxide
CX036_RS07630	COG2197	response regulator
CX036_RS07635	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CX036_RS07640	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CX036_RS07645	COG0189	ligase activity
CX036_RS07655	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CX036_RS07660	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CX036_RS07675	COG2423	ornithine cyclodeaminase activity
CX036_RS07685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CX036_RS07690	COG0765	amino acid transport
CX036_RS07695	COG0765	amino acid transport
CX036_RS07700	COG1126	abc transporter atp-binding protein
CX036_RS07755	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CX036_RS07765	COG2944	sequence-specific DNA binding
CX036_RS07775	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CX036_RS07780	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CX036_RS07785	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CX036_RS07790	COG0009	L-threonylcarbamoyladenylate synthase
CX036_RS07795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CX036_RS07800	COG1414	Transcriptional regulator
CX036_RS07815	COG0765	amino acid transport
CX036_RS07820	COG1126	abc transporter atp-binding protein
CX036_RS07825	COG0028	Belongs to the TPP enzyme family
CX036_RS07840	COG0028	Belongs to the TPP enzyme family
CX036_RS07845	COG0583	DNA-binding transcription factor activity
CX036_RS07850	COG4974	Belongs to the 'phage' integrase family
CX036_RS07855	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CX036_RS07860	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CX036_RS07875	COG1686	Belongs to the peptidase S11 family
CX036_RS07885	COG2814	Major facilitator Superfamily
CX036_RS07895	COG1074	ATP-dependent DNA helicase activity
CX036_RS07905	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CX036_RS07910	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CX036_RS07915	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CX036_RS07935	COG2321	neutral zinc metallopeptidase
CX036_RS07940	COG0009	L-threonylcarbamoyladenylate synthase
CX036_RS07985	COG3360	Dodecin
CX036_RS07990	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CX036_RS07995	COG2850	peptidyl-arginine hydroxylation
CX036_RS08000	COG3539	Fimbrial protein
CX036_RS08005	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CX036_RS08010	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CX036_RS08025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CX036_RS08030	COG0765	amino acid transport
CX036_RS08035	COG1126	abc transporter atp-binding protein
CX036_RS08040	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CX036_RS08045	COG1758	RNA polymerase activity
CX036_RS08050	COG0194	GDP metabolic process
CX036_RS08055	COG3258	Cytochrome c
CX036_RS08060	COG2863	cytochrome
CX036_RS08065	COG1028	Short-chain dehydrogenase reductase Sdr
CX036_RS08070	COG0791	NLP P60 protein
CX036_RS08075	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CX036_RS08095	COG1561	YicC-like family, N-terminal region
CX036_RS08100	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CX036_RS08120	COG2199	diguanylate cyclase activity
CX036_RS08120	COG2200	EAL domain
CX036_RS08125	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CX036_RS08135	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CX036_RS08140	COG0174	glutamine synthetase
CX036_RS08150	COG2204	response regulator
CX036_RS08155	COG0583	DNA-binding transcription factor activity
CX036_RS08160	COG1741	Belongs to the pirin family
CX036_RS08165	COG1741	Belongs to the pirin family
CX036_RS08175	COG3842	ATPase activity
CX036_RS08180	COG1178	ABC-type Fe3 transport system permease component
CX036_RS08185	COG1840	ABC-type Fe3 transport system, periplasmic component
CX036_RS08195	COG0583	DNA-binding transcription factor activity
CX036_RS08205	COG0656	L-ascorbic acid biosynthetic process
CX036_RS08220	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CX036_RS08225	COG0583	DNA-binding transcription factor activity
CX036_RS08240	COG0783	Belongs to the Dps family
CX036_RS08260	COG0463	Glycosyl transferase, family 2
CX036_RS08280	COG0438	transferase activity, transferring glycosyl groups
CX036_RS08295	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CX036_RS08320	COG0300	oxidoreductase activity
CX036_RS08365	COG0861	Integral membrane protein TerC family
CX036_RS08370	COG1028	Short-chain dehydrogenase reductase Sdr
CX036_RS08390	COG0714	Associated with various cellular activities
CX036_RS08425	COG3119	arylsulfatase activity
CX036_RS08450	COG2197	response regulator
CX036_RS08460	COG2944	sequence-specific DNA binding
CX036_RS08470	COG0625	glutathione transferase activity
CX036_RS08500	COG0179	Fumarylacetoacetate (FAA) hydrolase
CX036_RS08505	COG1028	Short-chain dehydrogenase reductase Sdr
CX036_RS08550	COG0431	NADPH-dependent FMN reductase
CX036_RS08580	COG1028	Short-chain dehydrogenase reductase Sdr
CX036_RS08585	COG0583	DNA-binding transcription factor activity
CX036_RS08605	COG2111	Na H antiporter
CX036_RS08605	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CX036_RS08610	COG1006	Multisubunit Na H antiporter MnhC subunit
CX036_RS08615	COG0651	ATP synthesis coupled electron transport
CX036_RS08620	COG1863	multisubunit Na H antiporter MnhE subunit
CX036_RS08625	COG2212	antiporter activity
CX036_RS08650	COG0590	tRNA wobble adenosine to inosine editing
CX036_RS08655	COG1619	proteins homologs of microcin C7 resistance protein MccF
CX036_RS08660	COG1024	Enoyl-CoA hydratase
CX036_RS08675	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CX036_RS08680	COG0488	(ABC) transporter
CX036_RS08715	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CX036_RS08715	COG1017	nitric oxide dioxygenase activity
CX036_RS08720	COG1959	2 iron, 2 sulfur cluster binding
CX036_RS08725	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CX036_RS08745	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CX036_RS08750	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CX036_RS08755	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CX036_RS08760	COG0084	hydrolase, TatD family'
CX036_RS08775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CX036_RS08785	COG1126	abc transporter atp-binding protein
CX036_RS08795	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CX036_RS08810	COG0028	Belongs to the TPP enzyme family
CX036_RS08820	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CX036_RS08820	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CX036_RS08830	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CX036_RS08880	COG4336	lyase activity
CX036_RS08890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CX036_RS08890	COG2205	protein histidine kinase activity
CX036_RS08895	COG2197	response regulator
CX036_RS08900	COG3064	Membrane
CX036_RS08900	COG3210	domain, Protein
CX036_RS08900	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CX036_RS08910	COG3121	Chaperone
CX036_RS08915	COG3188	usher protein
CX036_RS08920	COG3539	Fimbrial protein
CX036_RS08925	COG2831	hemolysin activation secretion protein
CX036_RS08940	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CX036_RS08990	COG0668	transmembrane transport
CX036_RS09010	COG0483	inositol monophosphate 1-phosphatase activity
CX036_RS09015	COG1253	flavin adenine dinucleotide binding
CX036_RS09020	COG1968	undecaprenyl-diphosphatase activity
CX036_RS09025	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CX036_RS09040	COG0215	cysteine-tRNA ligase activity
CX036_RS09050	COG0825	malonyl-CoA metabolic process
CX036_RS09060	COG0037	tRNA processing
CX036_RS09065	COG0527	aspartate kinase activity
CX036_RS09090	COG1250	3-hydroxyacyl-CoA dehydrogenase
CX036_RS09095	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CX036_RS09095	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CX036_RS09110	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CX036_RS09115	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
CX036_RS09120	COG1028	Short-chain dehydrogenase reductase Sdr
CX036_RS09130	COG0583	DNA-binding transcription factor activity
CX036_RS09155	COG3842	ATPase activity
CX036_RS09165	COG0446	pyridine nucleotide-disulphide oxidoreductase
CX036_RS09165	COG1902	pentaerythritol trinitrate reductase activity
CX036_RS09170	COG1414	Transcriptional regulator
CX036_RS09175	COG1832	CoA-binding protein
CX036_RS09185	COG0251	oxidation-reduction process
CX036_RS09210	COG1902	pentaerythritol trinitrate reductase activity
CX036_RS09220	COG1215	transferase activity, transferring glycosyl groups
CX036_RS09225	COG1649	PFAM Uncharacterised BCR, COG1649
CX036_RS09225	COG0726	polysaccharide deacetylase
CX036_RS09245	COG1846	Transcriptional regulator
CX036_RS09250	COG2197	response regulator
CX036_RS09265	COG0166	Belongs to the GPI family
CX036_RS09270	COG1045	serine acetyltransferase
CX036_RS09280	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CX036_RS09285	COG0483	inositol monophosphate 1-phosphatase activity
CX036_RS09290	COG1012	belongs to the aldehyde dehydrogenase family
CX036_RS09295	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CX036_RS09310	COG0210	DNA helicase
CX036_RS09315	COG0598	Magnesium transport protein CorA
CX036_RS09325	COG0747	negative chemotaxis
CX036_RS09330	COG0601	transmembrane transport
CX036_RS09335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CX036_RS09340	COG4172	Belongs to the ABC transporter superfamily
CX036_RS09345	COG1846	Transcriptional regulator
CX036_RS09400	COG4964	Belongs to the GSP D family
CX036_RS09440	COG2204	response regulator
CX036_RS09455	COG1595	DNA-templated transcription, initiation
CX036_RS09465	COG3474	cytochrome
CX036_RS09470	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CX036_RS09485	COG3384	dioxygenase
CX036_RS09490	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CX036_RS09520	COG2885	chlorophyll binding
CX036_RS09555	COG0697	spore germination
CX036_RS09560	COG0730	response to heat
CX036_RS09580	COG0583	DNA-binding transcription factor activity
CX036_RS09585	COG0427	acetyl-CoA hydrolase
CX036_RS09640	COG1250	3-hydroxyacyl-CoA dehydrogenase
CX036_RS09645	COG0154	amidase activity
CX036_RS09655	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CX036_RS09670	COG0495	leucyl-tRNA aminoacylation
CX036_RS09675	COG2814	Major facilitator Superfamily
CX036_RS09710	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CX036_RS09715	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CX036_RS09720	COG2814	Major facilitator Superfamily
CX036_RS09740	COG4176	ABC-type proline glycine betaine transport system permease component
CX036_RS09750	COG1942	4-Oxalocrotonate Tautomerase
CX036_RS09755	COG0183	Belongs to the thiolase family
CX036_RS09765	COG1802	Transcriptional regulator
CX036_RS09775	COG1024	Enoyl-CoA hydratase
CX036_RS09790	COG2032	superoxide dismutase activity
CX036_RS09805	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CX036_RS09830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CX036_RS09835	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CX036_RS09845	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CX036_RS09850	COG0736	holo-[acyl-carrier-protein] synthase activity
CX036_RS09855	COG1472	Belongs to the glycosyl hydrolase 3 family
CX036_RS09860	COG0322	excinuclease ABC activity
CX036_RS09865	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CX036_RS09875	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CX036_RS09875	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CX036_RS09880	COG2224	Isocitrate lyase
CX036_RS09900	COG0559	Belongs to the binding-protein-dependent transport system permease family
CX036_RS09910	COG4638	Rieske (2fe-2S)
CX036_RS09920	COG1024	Enoyl-CoA hydratase
CX036_RS09930	COG0633	Ferredoxin
CX036_RS09935	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX036_RS09950	COG0183	Belongs to the thiolase family
CX036_RS09965	COG0583	DNA-binding transcription factor activity
CX036_RS09995	COG2346	COG2346, Truncated hemoglobins
CX036_RS10125	COG2207	Transcriptional regulator
CX036_RS10170	COG1132	(ABC) transporter
CX036_RS10195	COG0659	secondary active sulfate transmembrane transporter activity
CX036_RS10225	COG2169	Transcriptional regulator
CX036_RS10230	COG5507	3-demethylubiquinone-9 3-methyltransferase
CX036_RS10235	COG0384	phenazine biosynthesis protein PhzF
CX036_RS10240	COG0583	DNA-binding transcription factor activity
CX036_RS10245	COG2733	membrane
CX036_RS10260	COG1012	belongs to the aldehyde dehydrogenase family
CX036_RS10265	COG3284	Transcriptional regulator
CX036_RS10290	COG1380	Effector of murein hydrolase LrgA
CX036_RS10295	COG4106	trans-aconitate 2-methyltransferase activity
CX036_RS10295	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CX036_RS10305	COG0156	8-amino-7-oxononanoate synthase activity
CX036_RS10375	COG1131	(ABC) transporter
CX036_RS10380	COG0842	Transport permease protein
CX036_RS10385	COG0628	permease
CX036_RS10415	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CX036_RS10425	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CX036_RS10430	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CX036_RS10435	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CX036_RS10440	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CX036_RS10445	COG0330	HflC and HflK could
CX036_RS10450	COG0330	HflC and HflK could
CX036_RS10455	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CX036_RS10460	COG1923	regulation of RNA biosynthetic process
CX036_RS10465	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CX036_RS10470	COG1160	GTP binding
CX036_RS10475	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CX036_RS10480	COG2976	Protein conserved in bacteria
CX036_RS10485	COG0124	histidyl-tRNA synthetase
CX036_RS10490	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CX036_RS10500	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CX036_RS10505	COG0105	UTP biosynthetic process
CX036_RS10510	COG0525	valine-tRNA ligase activity
CX036_RS10525	COG0642	Histidine kinase
CX036_RS10550	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CX036_RS10555	COG0336	Belongs to the RNA methyltransferase TrmD family
CX036_RS10560	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CX036_RS10565	COG0228	four-way junction DNA binding
CX036_RS10575	COG0425	Belongs to the sulfur carrier protein TusA family
CX036_RS10580	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CX036_RS10625	COG0154	amidase activity
CX036_RS10630	COG4172	Belongs to the ABC transporter superfamily
CX036_RS10635	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CX036_RS10640	COG0601	transmembrane transport
CX036_RS10645	COG0747	negative chemotaxis
CX036_RS10675	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CX036_RS10685	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CX036_RS10705	COG3395	kinase activity
CX036_RS10720	COG1024	Enoyl-CoA hydratase
CX036_RS10740	COG0633	Ferredoxin
CX036_RS10745	COG0443	Heat shock 70 kDa protein
CX036_RS10750	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CX036_RS10755	COG0316	Belongs to the HesB IscA family
CX036_RS10760	COG0822	iron-sulfur transferase activity
CX036_RS10765	COG1104	cysteine desulfurase activity
CX036_RS10775	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CX036_RS10780	COG0556	nucleotide-excision repair
CX036_RS10790	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CX036_RS10820	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CX036_RS10840	COG1028	Short-chain dehydrogenase reductase Sdr
CX036_RS10845	COG0183	Belongs to the thiolase family
CX036_RS10855	COG1024	Enoyl-CoA hydratase
CX036_RS10870	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX036_RS10875	COG0583	DNA-binding transcription factor activity
CX036_RS10880	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CX036_RS10885	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CX036_RS10890	COG0740	serine-type endopeptidase activity
CX036_RS10895	COG0544	peptidyl-prolyl cis-trans isomerase activity
CX036_RS10905	COG1278	Cold shock
CX036_RS10915	COG1278	Cold shock
CX036_RS10950	COG2171	N-acyltransferase activity
CX036_RS10955	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CX036_RS10960	COG2890	protein-(glutamine-N5) methyltransferase activity
CX036_RS10965	COG0488	(ABC) transporter
CX036_RS10970	COG4771	TonB-dependent receptor
CX036_RS10975	COG0210	DNA helicase
CX036_RS10995	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CX036_RS11000	COG0196	riboflavin kinase activity
CX036_RS11005	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CX036_RS11010	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CX036_RS11015	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CX036_RS11025	COG1522	sequence-specific DNA binding
CX036_RS11045	COG2951	lytic endotransglycosylase activity
CX036_RS11050	COG2833	Protein of unknown function (DUF455)
CX036_RS11070	COG0189	ligase activity
CX036_RS11070	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CX036_RS11075	COG1181	Belongs to the D-alanine--D-alanine ligase family
CX036_RS11075	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CX036_RS11080	COG3237	CsbD-like
CX036_RS11090	COG2823	Periplasmic or secreted lipoprotein
CX036_RS11105	COG4181	ATPase activity
CX036_RS11115	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CX036_RS11120	COG0584	glycerophosphoryl diester phosphodiesterase
CX036_RS11125	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CX036_RS11135	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CX036_RS11135	COG0678	peroxiredoxin activity
CX036_RS11145	COG0789	Transcriptional regulator
CX036_RS11150	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CX036_RS11180	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CX036_RS11185	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CX036_RS11195	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CX036_RS11200	COG2252	PERMEase
CX036_RS11210	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CX036_RS11240	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CX036_RS11245	COG2358	TRAP transporter, solute receptor (TAXI family
CX036_RS11280	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CX036_RS11285	COG1366	Belongs to the anti-sigma-factor antagonist family
CX036_RS11290	COG2172	sigma factor antagonist activity
CX036_RS11295	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CX036_RS11305	COG2208	phosphoserine phosphatase activity
CX036_RS11305	COG2770	Histidine kinase
CX036_RS11330	COG1595	DNA-templated transcription, initiation
CX036_RS11345	COG4792	protein secretion
CX036_RS11350	COG4791	protein targeting
CX036_RS11355	COG4794	Type iii secretion
CX036_RS11360	COG4790	Type iii secretion
CX036_RS11395	COG4669	(LipO)protein
CX036_RS11460	COG4789	Type iii secretion
CX036_RS11490	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CX036_RS11495	COG0840	transmembrane signaling receptor activity
CX036_RS11500	COG2233	PERMEase
CX036_RS11525	COG1840	ABC-type Fe3 transport system, periplasmic component
CX036_RS11530	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CX036_RS11535	COG1178	ABC-type Fe3 transport system permease component
CX036_RS11540	COG3842	ATPase activity
CX036_RS11545	COG0583	DNA-binding transcription factor activity
CX036_RS11565	COG0501	Belongs to the peptidase M48B family
CX036_RS11575	COG0697	spore germination
CX036_RS11585	COG1846	Transcriptional regulator
CX036_RS11595	COG1566	PFAM secretion protein HlyD family protein
CX036_RS11600	COG2814	Major facilitator Superfamily
CX036_RS11605	COG0473	3-isopropylmalate dehydrogenase activity
CX036_RS11615	COG0747	negative chemotaxis
CX036_RS11625	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CX036_RS11640	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CX036_RS11665	COG1012	belongs to the aldehyde dehydrogenase family
CX036_RS11675	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CX036_RS11680	COG1115	amino acid carrier protein
CX036_RS11685	COG0433	COG0433 Predicted ATPase
CX036_RS11690	COG0217	transcriptional regulatory protein
CX036_RS11695	COG0151	Belongs to the GarS family
CX036_RS11700	COG0408	coproporphyrinogen oxidase activity
CX036_RS11705	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CX036_RS11710	COG0799	negative regulation of ribosome biogenesis
CX036_RS11715	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CX036_RS11720	COG0424	maF-like protein
CX036_RS11725	COG3468	outer membrane autotransporter barrel domain protein
CX036_RS11765	COG1530	ribonuclease E activity
CX036_RS11770	COG0077	Prephenate dehydratase
CX036_RS11785	COG1132	(ABC) transporter
CX036_RS11790	COG0859	PFAM glycosyl transferase family 9
CX036_RS11815	COG2194	sulfuric ester hydrolase activity
CX036_RS11820	COG0438	transferase activity, transferring glycosyl groups
CX036_RS11825	COG0463	Glycosyl transferase, family 2
CX036_RS11830	COG0726	polysaccharide deacetylase
CX036_RS11835	COG0438	transferase activity, transferring glycosyl groups
CX036_RS11850	COG1643	Atp-dependent helicase
CX036_RS11855	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CX036_RS11855	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CX036_RS11860	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CX036_RS11870	COG0704	Plays a role in the regulation of phosphate uptake
CX036_RS11875	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CX036_RS11880	COG1960	acyl-CoA dehydrogenase activity
CX036_RS11905	COG1177	transmembrane transport
CX036_RS11910	COG1176	ABC-type spermidine putrescine transport system, permease component I
CX036_RS11915	COG3842	ATPase activity
CX036_RS11920	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CX036_RS11935	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CX036_RS11940	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CX036_RS11950	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CX036_RS11950	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CX036_RS11965	COG0372	Belongs to the citrate synthase family
CX036_RS11970	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CX036_RS11975	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CX036_RS11980	COG1053	succinate dehydrogenase
CX036_RS11985	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CX036_RS11990	COG2009	succinate dehydrogenase
CX036_RS11995	COG2188	Transcriptional regulator
CX036_RS12000	COG0039	L-malate dehydrogenase activity
CX036_RS12030	COG1981	membrane
CX036_RS12055	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CX036_RS12065	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CX036_RS12095	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CX036_RS12100	COG0148	phosphopyruvate hydratase activity
CX036_RS12110	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CX036_RS12115	COG0504	CTP synthase activity
CX036_RS12140	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CX036_RS12150	COG0747	negative chemotaxis
CX036_RS12155	COG4172	Belongs to the ABC transporter superfamily
CX036_RS12160	COG1446	asparaginase
CX036_RS12190	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CX036_RS12205	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CX036_RS12210	COG0697	spore germination
CX036_RS12215	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CX036_RS12225	COG3193	protein, possibly involved in utilization of glycolate and propanediol
CX036_RS12235	COG0791	NLP P60 protein
CX036_RS12250	COG0583	DNA-binding transcription factor activity
CX036_RS12265	COG0583	DNA-binding transcription factor activity
CX036_RS12275	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CX036_RS12290	COG0670	Belongs to the BI1 family
CX036_RS12295	COG3181	Tripartite tricarboxylate transporter family receptor
CX036_RS12310	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CX036_RS12320	COG1381	Involved in DNA repair and RecF pathway recombination
CX036_RS12325	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CX036_RS12330	COG0571	ribonuclease III activity
CX036_RS12335	COG0681	Belongs to the peptidase S26 family
CX036_RS12340	COG0481	GTPase activity
CX036_RS12345	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CX036_RS12370	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CX036_RS12375	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CX036_RS12390	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CX036_RS12395	COG0416	fatty acid biosynthetic process
CX036_RS12400	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CX036_RS12405	COG1399	metal-binding, possibly nucleic acid-binding protein
CX036_RS12410	COG0424	maF-like protein
CX036_RS12420	COG3023	N-Acetylmuramoyl-L-alanine amidase
CX036_RS12435	COG3022	response to hydroperoxide
CX036_RS12445	COG1028	Short-chain dehydrogenase reductase Sdr
CX036_RS12460	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CX036_RS12490	COG2814	Major facilitator Superfamily
CX036_RS12510	COG3706	GGDEF domain
CX036_RS12535	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CX036_RS12540	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CX036_RS12545	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CX036_RS12550	COG1674	ftsk spoiiie
CX036_RS12555	COG0492	ferredoxin-NADP+ reductase activity
CX036_RS12560	COG1193	negative regulation of DNA recombination
CX036_RS12580	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CX036_RS12595	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CX036_RS12600	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CX036_RS12605	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CX036_RS12615	COG0745	RESPONSE REGULATOR receiver
CX036_RS12660	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CX036_RS12680	COG0612	Peptidase, M16
CX036_RS12690	COG0443	Heat shock 70 kDa protein
CX036_RS12700	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CX036_RS12710	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CX036_RS12715	COG1420	regulation of RNA biosynthetic process
CX036_RS12720	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CX036_RS12725	COG0497	DNA recombination
CX036_RS12730	COG0735	belongs to the Fur family
CX036_RS12735	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CX036_RS12740	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CX036_RS12745	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CX036_RS12780	COG0446	pyridine nucleotide-disulphide oxidoreductase
CX036_RS12780	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CX036_RS12785	COG4311	Sarcosine oxidase, delta subunit
CX036_RS12790	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CX036_RS12800	COG0583	DNA-binding transcription factor activity
CX036_RS12810	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CX036_RS12835	COG4964	Belongs to the GSP D family
CX036_RS12895	COG0181	hydroxymethylbilane synthase activity
CX036_RS12900	COG0861	Integral membrane protein TerC family
CX036_RS12905	COG0861	Integral membrane protein TerC family
CX036_RS12910	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CX036_RS12915	COG0045	succinate-CoA ligase (ADP-forming) activity
CX036_RS12925	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CX036_RS12935	COG2137	regulation of response to DNA damage stimulus
CX036_RS12940	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CX036_RS12960	COG1024	Enoyl-CoA hydratase
CX036_RS12960	COG1250	3-hydroxyacyl-CoA dehydrogenase
CX036_RS12965	COG3842	ATPase activity
CX036_RS12980	COG1028	Short-chain dehydrogenase reductase Sdr
CX036_RS13000	COG0583	DNA-binding transcription factor activity
CX036_RS13005	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX036_RS13015	COG2974	May be involved in recombination
CX036_RS13020	COG0540	Belongs to the ATCase OTCase family
CX036_RS13085	COG0776	regulation of translation
CX036_RS13090	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CX036_RS13090	COG0072	phenylalanine-tRNA ligase activity
CX036_RS13095	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CX036_RS13100	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CX036_RS13105	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CX036_RS13115	COG0756	dUTP diphosphatase activity
CX036_RS13125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CX036_RS13140	COG0500	methyltransferase
CX036_RS13155	COG0586	Pfam SNARE associated Golgi protein
CX036_RS13185	COG1609	Transcriptional regulator
CX036_RS13190	COG4172	Belongs to the ABC transporter superfamily
CX036_RS13195	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CX036_RS13200	COG0601	transmembrane transport
CX036_RS13205	COG0747	negative chemotaxis
CX036_RS13225	COG1280	lysine exporter protein (LysE YggA)
CX036_RS13240	COG2814	Major facilitator Superfamily
CX036_RS13270	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CX036_RS13290	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CX036_RS13325	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CX036_RS13330	COG1116	anion transmembrane transporter activity
CX036_RS13340	COG1228	amidohydrolase
CX036_RS13355	COG0477	Major facilitator Superfamily
CX036_RS13365	COG3550	peptidyl-serine autophosphorylation
CX036_RS13380	COG0519	Catalyzes the synthesis of GMP from XMP
CX036_RS13380	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CX036_RS13425	COG0420	3'-5' exonuclease activity
CX036_RS13430	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CX036_RS13460	COG0395	ABC-type sugar transport system, permease component
CX036_RS13470	COG3842	ATPase activity
CX036_RS13495	COG3181	Tripartite tricarboxylate transporter family receptor
CX036_RS13530	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CX036_RS13555	COG0602	queuosine metabolic process
CX036_RS13560	COG0720	synthase
CX036_RS13565	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CX036_RS13570	COG0235	Class ii aldolase
CX036_RS13600	COG3064	Membrane
CX036_RS13600	COG3210	domain, Protein
CX036_RS13600	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CX036_RS13605	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CX036_RS13605	COG0047	phosphoribosylformylglycinamidine synthase activity
CX036_RS13610	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CX036_RS13615	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CX036_RS13615	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CX036_RS13620	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CX036_RS13640	COG3539	Fimbrial protein
CX036_RS13650	COG2050	protein possibly involved in aromatic compounds catabolism
CX036_RS13655	COG1024	Enoyl-CoA hydratase
CX036_RS13660	COG1012	belongs to the aldehyde dehydrogenase family
CX036_RS13680	COG2151	metal-sulfur cluster biosynthetic enzyme
CX036_RS13685	COG3396	Phenylacetate-CoA oxygenase
CX036_RS13690	COG3460	Phenylacetate-CoA oxygenase
CX036_RS13695	COG3396	Phenylacetate-CoA oxygenase
CX036_RS13700	COG3327	negative regulation of DNA-templated transcription, initiation
CX036_RS13710	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CX036_RS13715	COG0501	Belongs to the peptidase M48B family
CX036_RS13720	COG1162	GTPase activity
CX036_RS13735	COG0601	transmembrane transport
CX036_RS13740	COG0747	negative chemotaxis
CX036_RS13785	COG0668	transmembrane transport
CX036_RS13790	COG0165	Argininosuccinate lyase
CX036_RS13810	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CX036_RS13815	COG0303	'Molybdopterin
CX036_RS13820	COG0521	Mo-molybdopterin cofactor biosynthetic process
CX036_RS13835	COG0315	cyclic pyranopterin monophosphate synthase activity
CX036_RS13845	COG0412	Dienelactone hydrolase
CX036_RS13855	COG0678	peroxiredoxin activity
CX036_RS13865	COG0697	spore germination
CX036_RS13870	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CX036_RS13895	COG0789	Transcriptional regulator
CX036_RS13915	COG1028	Short-chain dehydrogenase reductase Sdr
CX036_RS13925	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CX036_RS13930	COG1845	cytochrome c oxidase, subunit III
CX036_RS13935	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CX036_RS13945	COG0477	Major facilitator Superfamily
CX036_RS13980	COG1309	transcriptional regulator
CX036_RS13985	COG2271	Major facilitator Superfamily
CX036_RS14020	COG0506	proline dehydrogenase activity
CX036_RS14020	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CX036_RS14020	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CX036_RS14030	COG3008	intermembrane lipid transfer
CX036_RS14030	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CX036_RS14035	COG2995	paraquat-inducible protein a
CX036_RS14040	COG0542	response to heat
CX036_RS14045	COG4953	penicillin-binding protein 1C
CX036_RS14055	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CX036_RS14060	COG1278	Cold shock
CX036_RS14070	COG0183	Belongs to the thiolase family
CX036_RS14075	COG0038	chloride channel
CX036_RS14080	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CX036_RS14085	COG1570	exodeoxyribonuclease VII activity
CX036_RS14095	COG0811	peptide transport
CX036_RS14100	COG0848	biopolymer transport protein
CX036_RS14105	COG1663	tetraacyldisaccharide 4'-kinase activity
CX036_RS14110	COG2835	tetraacyldisaccharide 4'-kinase activity
CX036_RS14115	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CX036_RS14120	COG0563	adenylate kinase activity
CX036_RS14130	COG0728	peptidoglycan biosynthetic process
CX036_RS14140	COG0268	Binds directly to 16S ribosomal RNA
CX036_RS14175	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CX036_RS14200	COG0436	Aminotransferase
CX036_RS14205	COG3737	Protein of unknown function (DUF498/DUF598)
CX036_RS14210	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CX036_RS14215	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CX036_RS14220	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CX036_RS14230	COG0305	Participates in initiation and elongation during chromosome replication
CX036_RS14240	COG0359	binds to the 23S rRNA
CX036_RS14245	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CX036_RS14250	COG2965	DNA replication, synthesis of RNA primer
CX036_RS14255	COG0360	Binds together with S18 to 16S ribosomal RNA
CX036_RS14260	COG1469	GTP cyclohydrolase I activity
CX036_RS14265	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CX036_RS14270	COG0142	geranyltranstransferase activity
CX036_RS14275	COG1722	exodeoxyribonuclease VII activity
CX036_RS14285	COG3181	Tripartite tricarboxylate transporter family receptor
CX036_RS14305	COG2239	Acts as a magnesium transporter
CX036_RS14315	COG2855	membrane
CX036_RS14325	COG1473	amidohydrolase
CX036_RS14330	COG0318	PFAM AMP-dependent synthetase and ligase
CX036_RS14355	COG1501	Belongs to the glycosyl hydrolase 31 family
CX036_RS14360	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CX036_RS14365	COG2011	ABC-type metal ion transport system permease component
CX036_RS14385	COG1454	alcohol dehydrogenase
CX036_RS14415	COG2186	Transcriptional regulator
CX036_RS14420	COG3181	Tripartite tricarboxylate transporter family receptor
CX036_RS14440	COG1175	transmembrane transport
CX036_RS14445	COG0395	ABC-type sugar transport system, permease component
CX036_RS14450	COG3842	ATPase activity
CX036_RS14465	COG1653	transport
CX036_RS14485	COG2818	Glycosylase
CX036_RS14490	COG2982	Protein involved in outer membrane biogenesis
CX036_RS14500	COG1309	transcriptional regulator
CX036_RS14505	COG1028	Short-chain dehydrogenase reductase Sdr
CX036_RS14565	COG0583	DNA-binding transcription factor activity
CX036_RS14570	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CX036_RS14575	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CX036_RS14590	COG1028	Short-chain dehydrogenase reductase Sdr
CX036_RS14595	COG0477	Major facilitator Superfamily
CX036_RS14605	COG0583	DNA-binding transcription factor activity
CX036_RS14610	COG1448	Aminotransferase
CX036_RS14615	COG1418	mRNA catabolic process
CX036_RS14640	COG1063	alcohol dehydrogenase
CX036_RS14660	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CX036_RS14670	COG0318	PFAM AMP-dependent synthetase and ligase
CX036_RS14680	COG1522	sequence-specific DNA binding
CX036_RS14685	COG3181	Tripartite tricarboxylate transporter family receptor
CX036_RS14690	COG0307	riboflavin synthase, alpha
CX036_RS14695	COG0154	amidase activity
CX036_RS14715	COG2807	transmembrane transport
CX036_RS14720	COG0590	tRNA wobble adenosine to inosine editing
CX036_RS14730	COG0583	DNA-binding transcription factor activity
CX036_RS14765	COG0559	Belongs to the binding-protein-dependent transport system permease family
CX036_RS14770	COG0251	oxidation-reduction process
CX036_RS14775	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CX036_RS14785	COG1414	Transcriptional regulator
CX036_RS14790	COG1028	Short-chain dehydrogenase reductase Sdr
CX036_RS14805	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CX036_RS14820	COG1024	Enoyl-CoA hydratase
CX036_RS14825	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX036_RS14830	COG0154	amidase activity
CX036_RS14870	COG3909	cytochrome
CX036_RS14875	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CX036_RS14880	COG0625	glutathione transferase activity
CX036_RS14885	COG0730	response to heat
CX036_RS14890	COG0482	sulfurtransferase activity
CX036_RS14895	COG0583	DNA-binding transcription factor activity
CX036_RS14935	COG2819	hydrolase of the alpha beta superfamily
CX036_RS14940	COG0247	lactate metabolic process
CX036_RS14945	COG0277	FAD linked oxidase domain protein
CX036_RS14950	COG0277	FAD linked oxidase domain protein
CX036_RS14955	COG0277	FAD linked oxidase domain protein
CX036_RS14960	COG3064	Membrane
CX036_RS14960	COG3064	Membrane
CX036_RS14960	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CX036_RS14960	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CX036_RS14960	COG3210	domain, Protein
CX036_RS14960	COG3210	domain, Protein
CX036_RS14965	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CX036_RS14970	COG0312	modulator of DNA gyrase
CX036_RS15005	COG1666	GTP binding
CX036_RS15050	COG3220	belongs to the UPF0276 family
CX036_RS15070	COG0640	Transcriptional regulator
CX036_RS15075	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CX036_RS15080	COG1845	cytochrome c oxidase, subunit III
CX036_RS15085	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CX036_RS15095	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CX036_RS15130	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX036_RS15135	COG0583	DNA-binding transcription factor activity
CX036_RS15170	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CX036_RS15170	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CX036_RS15185	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CX036_RS15190	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CX036_RS15200	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CX036_RS15215	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CX036_RS15220	COG0316	Belongs to the HesB IscA family
CX036_RS15230	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CX036_RS15235	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CX036_RS15240	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CX036_RS15245	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CX036_RS15250	COG0312	modulator of DNA gyrase
CX036_RS15255	COG3028	Belongs to the UPF0307 family
CX036_RS15270	COG1116	anion transmembrane transporter activity
CX036_RS15275	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CX036_RS15280	COG1335	isochorismatase
CX036_RS15285	COG0346	lactoylglutathione lyase activity
CX036_RS15290	COG0513	Belongs to the DEAD box helicase family
CX036_RS15295	COG3069	C4-dicarboxylate transmembrane transporter activity
CX036_RS15300	COG1802	Transcriptional regulator
CX036_RS15315	COG1042	CoA-binding domain protein
CX036_RS15315	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CX036_RS15315	COG0045	succinate-CoA ligase (ADP-forming) activity
CX036_RS15320	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CX036_RS15335	COG1522	sequence-specific DNA binding
CX036_RS15370	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CX036_RS15375	COG1696	Membrane protein involved in D-alanine export
CX036_RS15400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CX036_RS15415	COG0439	Biotin carboxylase
CX036_RS15420	COG0511	ligase activity, forming carbon-carbon bonds
CX036_RS15425	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CX036_RS15430	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CX036_RS15435	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CX036_RS15440	COG3150	esterase
CX036_RS15445	COG0557	exoribonuclease II activity
CX036_RS15455	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CX036_RS15475	COG1522	sequence-specific DNA binding
CX036_RS15480	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CX036_RS15485	COG1028	Short-chain dehydrogenase reductase Sdr
CX036_RS15505	COG0653	protein targeting
CX036_RS15510	COG0739	heme binding
CX036_RS15520	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CX036_RS15525	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CX036_RS15535	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CX036_RS15540	COG1181	Belongs to the D-alanine--D-alanine ligase family
CX036_RS15545	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CX036_RS15550	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CX036_RS15560	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CX036_RS15565	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CX036_RS15570	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CX036_RS15580	COG3116	cell division
CX036_RS15585	COG0275	rRNA processing
CX036_RS15590	COG2001	Belongs to the MraZ family
CX036_RS15600	COG0488	(ABC) transporter
CX036_RS15605	COG0418	dihydroorotase activity
CX036_RS15610	COG1473	amidohydrolase
CX036_RS15660	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CX036_RS15665	COG4654	Cytochrome c, class I
CX036_RS15670	COG0129	dihydroxy-acid dehydratase activity
CX036_RS15675	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CX036_RS15725	COG2084	Dehydrogenase
CX036_RS15745	COG2096	Adenosyltransferase
CX036_RS15760	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CX036_RS15765	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CX036_RS15775	COG0523	cobalamin synthesis protein
CX036_RS15780	COG0735	belongs to the Fur family
CX036_RS15795	COG0803	Belongs to the bacterial solute-binding protein 9 family
CX036_RS15805	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CX036_RS15815	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CX036_RS15825	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CX036_RS15830	COG1560	Kdo2-lipid A biosynthetic process
CX036_RS15840	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CX036_RS15855	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CX036_RS15860	COG1950	PFAM Membrane protein of
CX036_RS15875	COG0583	DNA-binding transcription factor activity
CX036_RS15885	COG0477	Major facilitator Superfamily
CX036_RS15900	COG0617	tRNA 3'-terminal CCA addition
CX036_RS15910	COG0513	Belongs to the DEAD box helicase family
CX036_RS15915	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CX036_RS15925	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CX036_RS15930	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CX036_RS16005	COG0405	Gamma-glutamyltransferase
CX036_RS16015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CX036_RS16045	COG1309	transcriptional regulator
CX036_RS16060	COG0745	RESPONSE REGULATOR receiver
CX036_RS16110	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CX036_RS16135	COG0582	viral genome integration into host DNA
CX036_RS16140	COG0012	GTP binding
CX036_RS16150	COG0193	aminoacyl-tRNA hydrolase activity
CX036_RS16155	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CX036_RS16160	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CX036_RS16170	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CX036_RS16175	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CX036_RS16185	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CX036_RS16210	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CX036_RS16220	COG1368	sulfuric ester hydrolase activity
CX036_RS16225	COG0642	Histidine kinase
CX036_RS16230	COG0745	RESPONSE REGULATOR receiver
CX036_RS16235	COG0277	FAD linked oxidase domain protein
CX036_RS16250	COG0166	Belongs to the GPI family
CX036_RS16255	COG0438	transferase activity, transferring glycosyl groups
CX036_RS16260	COG0438	transferase activity, transferring glycosyl groups
CX036_RS16275	COG0438	transferase activity, transferring glycosyl groups
CX036_RS16290	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CX036_RS16295	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CX036_RS16300	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
CX036_RS16310	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CX036_RS16320	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CX036_RS16325	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CX036_RS16335	COG0747	negative chemotaxis
CX036_RS16340	COG0601	transmembrane transport
CX036_RS16345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CX036_RS16365	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CX036_RS16370	COG0830	nickel cation binding
CX036_RS16380	COG0804	urea catabolic process
CX036_RS16385	COG0832	Belongs to the urease beta subunit family
CX036_RS16395	COG0831	urea catabolic process
CX036_RS16400	COG0829	nickel cation binding
CX036_RS16430	COG2188	Transcriptional regulator
CX036_RS16455	COG2719	SpoVR family
CX036_RS16460	COG2718	Belongs to the UPF0229 family
CX036_RS16480	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX036_RS16495	COG1960	acyl-CoA dehydrogenase activity
CX036_RS16545	COG2030	dehydratase
CX036_RS16595	COG0328	RNA-DNA hybrid ribonuclease activity
CX036_RS16600	COG2226	methyltransferase
CX036_RS16605	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CX036_RS16610	COG0741	lytic transglycosylase activity
CX036_RS16610	COG1388	LysM domain
CX036_RS16630	COG2979	Protein of unknown function (DUF533)
CX036_RS16665	COG1271	oxidase subunit
CX036_RS16670	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CX036_RS16675	COG0850	regulation of cytokinetic process
CX036_RS16680	COG2894	cell division
CX036_RS16685	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CX036_RS16720	COG0601	transmembrane transport
CX036_RS16730	COG1215	transferase activity, transferring glycosyl groups
CX036_RS16745	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CX036_RS16755	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CX036_RS16775	COG0318	PFAM AMP-dependent synthetase and ligase
CX036_RS16780	COG2188	Transcriptional regulator
CX036_RS16785	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CX036_RS16790	COG2814	Major facilitator Superfamily
CX036_RS16800	COG0259	pyridoxamine-phosphate oxidase activity
CX036_RS16805	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CX036_RS16820	COG0583	DNA-binding transcription factor activity
CX036_RS16845	COG0134	indole-3-glycerol-phosphate synthase activity
CX036_RS16850	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CX036_RS16855	COG0512	Glutamine amidotransferase of anthranilate synthase
CX036_RS16865	COG0546	phosphoglycolate phosphatase activity
CX036_RS16870	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CX036_RS16875	COG2967	ApaG domain
CX036_RS16880	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CX036_RS16885	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CX036_RS16890	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CX036_RS16895	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CX036_RS16905	COG0037	tRNA processing
CX036_RS16915	COG3634	alkyl hydroperoxide reductase activity
CX036_RS16920	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CX036_RS16925	COG1024	Enoyl-CoA hydratase
CX036_RS16950	COG0356	it plays a direct role in the translocation of protons across the membrane
CX036_RS16960	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CX036_RS16965	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CX036_RS16970	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CX036_RS16975	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CX036_RS16980	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CX036_RS16985	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CX036_RS16995	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CX036_RS17000	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CX036_RS17005	COG0210	DNA helicase
CX036_RS17015	COG2195	Cleaves the N-terminal amino acid of tripeptides
CX036_RS17025	COG4172	Belongs to the ABC transporter superfamily
CX036_RS17030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CX036_RS17035	COG0601	transmembrane transport
CX036_RS17055	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CX036_RS17060	COG1024	Enoyl-CoA hydratase
CX036_RS17065	COG1024	Enoyl-CoA hydratase
CX036_RS17120	COG2132	Multicopper oxidase
CX036_RS17130	COG1250	3-hydroxyacyl-CoA dehydrogenase
CX036_RS17130	COG1024	Enoyl-CoA hydratase
CX036_RS17140	COG1414	Transcriptional regulator
CX036_RS17150	COG0154	amidase activity
CX036_RS17180	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CX036_RS17185	COG3568	Endonuclease Exonuclease Phosphatase
CX036_RS17190	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CX036_RS17225	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CX036_RS17235	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CX036_RS17250	COG1137	ATPase activity
CX036_RS17265	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CX036_RS17270	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CX036_RS17270	COG2010	Cytochrome c
CX036_RS17280	COG1660	Displays ATPase and GTPase activities
CX036_RS17285	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CX036_RS17320	COG3181	Tripartite tricarboxylate transporter family receptor
CX036_RS17330	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CX036_RS17335	COG2890	protein-(glutamine-N5) methyltransferase activity
CX036_RS17340	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CX036_RS17345	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CX036_RS17395	COG1960	acyl-CoA dehydrogenase activity
CX036_RS17405	COG0183	Belongs to the thiolase family
CX036_RS17410	COG1522	sequence-specific DNA binding
CX036_RS17415	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CX036_RS17435	COG1024	Enoyl-CoA hydratase
CX036_RS17450	COG0604	alcohol dehydrogenase
CX036_RS17470	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CX036_RS17480	COG1960	acyl-CoA dehydrogenase activity
CX036_RS17485	COG1960	acyl-CoA dehydrogenase activity
CX036_RS17490	COG0277	FAD linked oxidase domain protein
CX036_RS17500	COG3181	Tripartite tricarboxylate transporter family receptor
CX036_RS17525	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CX036_RS17535	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX036_RS17540	COG3181	Tripartite tricarboxylate transporter family receptor
CX036_RS17545	COG1960	acyl-CoA dehydrogenase activity
CX036_RS17565	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CX036_RS17570	COG1024	Enoyl-CoA hydratase
CX036_RS17575	COG1960	acyl-CoA dehydrogenase activity
CX036_RS17595	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CX036_RS17600	COG0022	dehydrogenase e1 component
CX036_RS17605	COG1024	Enoyl-CoA hydratase
CX036_RS17610	COG0508	dehydrogenase complex catalyzes the overall conversion of
CX036_RS17630	COG0683	leucine binding
CX036_RS17635	COG0559	Belongs to the binding-protein-dependent transport system permease family
CX036_RS17640	COG0411	ABC transporter
CX036_RS17650	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CX036_RS17665	COG3181	Tripartite tricarboxylate transporter family receptor
CX036_RS17690	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CX036_RS17695	COG0793	Belongs to the peptidase S41A family
CX036_RS17700	COG4942	peptidase
CX036_RS17705	COG0588	phosphoglycerate mutase activity
CX036_RS17710	COG1054	Belongs to the UPF0176 family
CX036_RS17715	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CX036_RS17720	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CX036_RS17725	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CX036_RS17730	COG3181	Tripartite tricarboxylate transporter family receptor
CX036_RS17745	COG2226	methyltransferase
CX036_RS17750	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CX036_RS17765	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CX036_RS17770	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CX036_RS17795	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CX036_RS17820	COG1335	isochorismatase
CX036_RS17825	COG2309	aminopeptidase activity
CX036_RS17835	COG3473	Maleate cis-trans isomerase
CX036_RS17845	COG2068	MobA-Related Protein
CX036_RS17870	COG2204	response regulator
CX036_RS17875	COG5000	phosphorelay sensor kinase activity
CX036_RS17885	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CX036_RS17885	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CX036_RS17895	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
CX036_RS17930	COG0583	DNA-binding transcription factor activity
CX036_RS17950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CX036_RS17955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CX036_RS17970	COG0758	DNA mediated transformation
CX036_RS17975	COG1522	sequence-specific DNA binding
CX036_RS17985	COG0242	peptide deformylase activity
CX036_RS18000	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CX036_RS18010	COG0546	phosphoglycolate phosphatase activity
CX036_RS18030	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CX036_RS18035	COG1942	4-Oxalocrotonate Tautomerase
CX036_RS18040	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CX036_RS18065	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CX036_RS18085	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CX036_RS18090	COG1024	Enoyl-CoA hydratase
CX036_RS18095	COG1414	Transcriptional regulator
CX036_RS18100	COG0318	PFAM AMP-dependent synthetase and ligase
CX036_RS18105	COG3181	Tripartite tricarboxylate transporter family receptor
CX036_RS18150	COG3422	double-strand break repair
CX036_RS18155	COG0330	HflC and HflK could
CX036_RS18165	COG0251	oxidation-reduction process
CX036_RS18215	COG3723	Recombinational DNA repair protein, rece pathway
CX036_RS18250	COG0582	viral genome integration into host DNA
CX036_RS18285	COG0706	membrane insertase activity
CX036_RS18290	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CX036_RS18295	COG0594	ribonuclease P activity
CX036_RS18300	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CX036_RS18305	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CX036_RS18320	COG1414	Transcriptional regulator
CX036_RS18325	COG0154	amidase activity
CX036_RS18340	COG1304	FMN binding
CX036_RS18390	COG0183	Belongs to the thiolase family
CX036_RS18395	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CX036_RS18410	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CX036_RS18415	COG3181	Tripartite tricarboxylate transporter family receptor
CX036_RS18425	COG2358	TRAP transporter, solute receptor (TAXI family
CX036_RS18435	COG1629	transport
CX036_RS18440	COG2922	Belongs to the Smg family
CX036_RS18465	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CX036_RS18470	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CX036_RS18475	COG1028	Short-chain dehydrogenase reductase Sdr
CX036_RS18480	COG1012	belongs to the aldehyde dehydrogenase family
CX036_RS18490	COG0028	Belongs to the TPP enzyme family
CX036_RS18495	COG1522	sequence-specific DNA binding
CX036_RS18500	COG3781	membrane
CX036_RS18510	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CX036_RS18530	COG4206	TonB-dependent receptor
CX036_RS18535	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CX036_RS18540	COG2022	thiamine diphosphate biosynthetic process
CX036_RS18545	COG0351	phosphomethylpyrimidine kinase
CX036_RS18550	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CX036_RS18565	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CX036_RS18575	COG0628	permease
CX036_RS18585	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CX036_RS18600	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CX036_RS18605	COG0049	tRNA binding
CX036_RS18610	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CX036_RS18615	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CX036_RS18620	COG0051	transcription antitermination factor activity, RNA binding
CX036_RS18625	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CX036_RS18630	COG0088	Forms part of the polypeptide exit tunnel
CX036_RS18635	COG0089	rRNA binding
CX036_RS18640	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CX036_RS18645	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CX036_RS18650	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CX036_RS18655	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CX036_RS18660	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CX036_RS18665	COG0255	Belongs to the universal ribosomal protein uL29 family
CX036_RS18670	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CX036_RS18690	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CX036_RS18695	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CX036_RS18700	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CX036_RS18705	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CX036_RS18710	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CX036_RS18715	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CX036_RS18720	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CX036_RS18725	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CX036_RS18730	COG1841	ribosomal large subunit assembly
CX036_RS18735	COG0200	Binds to the 23S rRNA
CX036_RS18740	COG0201	protein transport
CX036_RS18745	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CX036_RS18750	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CX036_RS18755	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CX036_RS18760	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CX036_RS18765	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CX036_RS18770	COG0202	RNA polymerase activity
CX036_RS18775	COG0203	ribosomal protein L17
CX036_RS18780	COG0537	adenosine 5'-monophosphoramidase activity
CX036_RS18785	COG1324	tolerance protein
CX036_RS18790	COG4232	protein-disulfide reductase activity
CX036_RS18805	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CX036_RS18815	COG1333	cytochrome c biogenesis protein
CX036_RS18820	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CX036_RS18835	COG1965	Belongs to the frataxin family
CX036_RS18845	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CX036_RS18850	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CX036_RS18855	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CX036_RS18870	COG2814	Major facilitator Superfamily
CX036_RS18875	COG0629	single-stranded DNA binding
CX036_RS18915	COG0402	S-adenosylhomocysteine deaminase activity
CX036_RS18925	COG0438	transferase activity, transferring glycosyl groups
CX036_RS18945	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CX036_RS18970	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CX036_RS18995	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CX036_RS19000	COG1956	GAF domain-containing protein
CX036_RS19005	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CX036_RS19020	COG1652	LysM domain
CX036_RS19060	COG3181	Tripartite tricarboxylate transporter family receptor
CX036_RS19075	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CX036_RS19090	COG1024	Enoyl-CoA hydratase
CX036_RS19105	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX036_RS19110	COG1309	transcriptional regulator
CX036_RS19115	COG2816	NAD+ diphosphatase activity
CX036_RS19120	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CX036_RS19205	COG2814	Major facilitator Superfamily
CX036_RS19210	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CX036_RS19230	COG1999	signal sequence binding
CX036_RS19235	COG0109	protoheme IX farnesyltransferase activity
CX036_RS19275	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CX036_RS19295	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CX036_RS19300	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CX036_RS19310	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CX036_RS19315	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CX036_RS19325	COG0069	glutamate synthase activity
CX036_RS19325	COG0067	glutamate synthase
CX036_RS19325	COG0070	glutamate synthase
CX036_RS19335	COG3047	cAMP biosynthetic process
CX036_RS19345	COG1127	ABC transporter
CX036_RS19350	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CX036_RS19355	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CX036_RS19360	COG2853	Lipoprotein
CX036_RS19375	COG0842	Transport permease protein
CX036_RS19385	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CX036_RS19390	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CX036_RS19395	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CX036_RS19400	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CX036_RS19405	COG0131	Imidazoleglycerol-phosphate dehydratase
CX036_RS19410	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CX036_RS19415	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CX036_RS19420	COG0107	imidazoleglycerol-phosphate synthase activity
CX036_RS19425	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CX036_RS19430	COG0140	phosphoribosyl-ATP diphosphatase activity
CX036_RS19435	COG0537	adenosine 5'-monophosphoramidase activity
CX036_RS19440	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CX036_RS19445	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CX036_RS19460	COG3181	Tripartite tricarboxylate transporter family receptor
CX036_RS19495	COG3702	type iv secretory pathway
CX036_RS19500	COG3451	type IV secretory pathway VirB4
CX036_RS19515	COG3736	Type IV secretory pathway, component VirB8
CX036_RS19520	COG3504	Conjugal transfer protein
CX036_RS19525	COG2948	multi-organism process
CX036_RS19530	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
CX036_RS19540	COG0697	spore germination
CX036_RS19560	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CX036_RS19565	COG0747	negative chemotaxis
CX036_RS19570	COG0601	transmembrane transport
CX036_RS19575	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CX036_RS19590	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CX036_RS19600	COG0494	nUDIX hydrolase
CX036_RS19645	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
CX036_RS19650	COG0237	dephospho-CoA kinase activity
CX036_RS19655	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CX036_RS19670	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CX036_RS19675	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CX036_RS19685	COG0477	Major facilitator Superfamily
CX036_RS19690	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CX036_RS19705	COG1126	abc transporter atp-binding protein
CX036_RS19710	COG0765	amino acid transport
CX036_RS19715	COG4597	amino acid ABC transporter
CX036_RS19720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CX036_RS19725	COG2884	Cell division ATP-binding protein ftsE
CX036_RS19730	COG2177	Part of the ABC transporter FtsEX involved in
CX036_RS19735	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CX036_RS19745	COG1194	a g-specific adenine glycosylase
CX036_RS19755	COG2226	methyltransferase
CX036_RS19765	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX036_RS19770	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX036_RS19785	COG1024	Enoyl-CoA hydratase
CX036_RS19805	COG1024	Enoyl-CoA hydratase
CX036_RS19810	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX036_RS19825	COG0753	catalase activity
CX036_RS19830	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CX036_RS19835	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CX036_RS19845	COG2175	clavaminate synthase activity
CX036_RS19850	COG1473	amidohydrolase
CX036_RS19865	COG4608	Belongs to the ABC transporter superfamily
CX036_RS19870	COG0444	Belongs to the ABC transporter superfamily
CX036_RS19885	COG0747	negative chemotaxis
CX036_RS19890	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CX036_RS19925	COG0436	Aminotransferase
CX036_RS19930	COG1278	Cold shock