locus-tag	class	description
CY774_RS00005	COG0445	tRNA wobble uridine modification
CY774_RS00010	COG0357	Ribosomal RNA small subunit methyltransferase G
CY774_RS00015	COG1192	Involved in chromosome partitioning
CY774_RS00025	COG1475	DNA binding
CY774_RS00050	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CY774_RS00060	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CY774_RS00070	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CY774_RS00075	COG0081	regulation of translation
CY774_RS00080	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CY774_RS00085	COG0222	ribosome binding
CY774_RS00090	COG0085	RNA polymerase activity
CY774_RS00095	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CY774_RS00145	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CY774_RS00170	COG1024	Enoyl-CoA hydratase
CY774_RS00190	COG0752	glycyl-tRNA synthetase alpha subunit
CY774_RS00195	COG0751	glycine-tRNA ligase activity
CY774_RS00200	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CY774_RS00205	COG0204	Acyl-transferase
CY774_RS00220	COG0242	peptide deformylase activity
CY774_RS00260	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CY774_RS00265	COG2813	Specifically methylates the guanine in position
CY774_RS00265	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CY774_RS00280	COG2223	nitrite transmembrane transporter activity
CY774_RS00290	COG1794	racemase activity, acting on amino acids and derivatives
CY774_RS00295	COG1126	abc transporter atp-binding protein
CY774_RS00300	COG0765	amino acid transport
CY774_RS00305	COG0765	amino acid transport
CY774_RS00310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CY774_RS00375	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CY774_RS00405	COG0326	Molecular chaperone. Has ATPase activity
CY774_RS00410	COG0625	glutathione transferase activity
CY774_RS00425	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CY774_RS00430	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CY774_RS00460	COG0438	transferase activity, transferring glycosyl groups
CY774_RS00465	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CY774_RS00470	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CY774_RS00500	COG0859	PFAM glycosyl transferase family 9
CY774_RS00515	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CY774_RS00525	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CY774_RS00530	COG1127	ABC transporter
CY774_RS00550	COG1686	Belongs to the peptidase S11 family
CY774_RS00560	COG2921	Belongs to the UPF0250 family
CY774_RS00565	COG0321	lipoyl(octanoyl) transferase activity
CY774_RS00570	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CY774_RS00605	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CY774_RS00615	COG0018	arginyl-trna synthetase
CY774_RS00635	COG0395	ABC-type sugar transport system, permease component
CY774_RS00640	COG1175	transmembrane transport
CY774_RS00645	COG1653	transport
CY774_RS00650	COG3842	ATPase activity
CY774_RS00655	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CY774_RS00670	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CY774_RS00690	COG1609	Transcriptional regulator
CY774_RS00700	COG0154	amidase activity
CY774_RS00705	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CY774_RS00715	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CY774_RS00725	COG0583	DNA-binding transcription factor activity
CY774_RS00745	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CY774_RS00760	COG1802	Transcriptional regulator
CY774_RS00775	COG1024	Enoyl-CoA hydratase
CY774_RS00785	COG3181	Tripartite tricarboxylate transporter family receptor
CY774_RS00800	COG1984	allophanate hydrolase subunit 2
CY774_RS00805	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CY774_RS00815	COG0583	DNA-binding transcription factor activity
CY774_RS00820	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CY774_RS00830	COG5002	protein histidine kinase activity
CY774_RS00840	COG5002	protein histidine kinase activity
CY774_RS00845	COG0745	RESPONSE REGULATOR receiver
CY774_RS00850	COG2226	methyltransferase
CY774_RS00865	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CY774_RS00885	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CY774_RS00895	COG0513	Belongs to the DEAD box helicase family
CY774_RS00900	COG1280	lysine exporter protein (LysE YggA)
CY774_RS00905	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CY774_RS00945	COG1054	Belongs to the UPF0176 family
CY774_RS00950	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CY774_RS00950	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CY774_RS00960	COG0489	protein tyrosine kinase activity
CY774_RS00975	COG0717	Belongs to the dCTP deaminase family
CY774_RS01005	COG2081	HI0933 family
CY774_RS01015	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CY774_RS01025	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CY774_RS01030	COG0509	glycine decarboxylation via glycine cleavage system
CY774_RS01035	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CY774_RS01035	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CY774_RS01075	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CY774_RS01090	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CY774_RS01100	COG1414	Transcriptional regulator
CY774_RS01105	COG1028	Short-chain dehydrogenase reductase Sdr
CY774_RS01110	COG2031	fatty acid transporter
CY774_RS01115	COG1250	3-hydroxyacyl-CoA dehydrogenase
CY774_RS01125	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CY774_RS01130	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CY774_RS01140	COG4257	antibiotic catabolic process
CY774_RS01165	COG1012	belongs to the aldehyde dehydrogenase family
CY774_RS01170	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CY774_RS01175	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CY774_RS01200	COG1028	Short-chain dehydrogenase reductase Sdr
CY774_RS01210	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CY774_RS01220	COG2188	Transcriptional regulator
CY774_RS01225	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CY774_RS01250	COG0617	tRNA 3'-terminal CCA addition
CY774_RS01265	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CY774_RS01270	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CY774_RS01275	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CY774_RS01280	COG0586	Pfam SNARE associated Golgi protein
CY774_RS01285	COG0860	N-Acetylmuramoyl-L-alanine amidase
CY774_RS01290	COG0802	atpase or kinase
CY774_RS01295	COG0114	fumarate hydratase activity
CY774_RS01305	COG3181	Tripartite tricarboxylate transporter family receptor
CY774_RS01315	COG0405	Gamma-glutamyltransferase
CY774_RS01320	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CY774_RS01355	COG1294	oxidase, subunit
CY774_RS01365	COG4988	ABC transporter
CY774_RS01370	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CY774_RS01425	COG2969	positive regulation of protein catabolic process
CY774_RS01430	COG0625	glutathione transferase activity
CY774_RS01435	COG2857	Cytochrome c1
CY774_RS01440	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CY774_RS01445	COG0723	plastoquinol--plastocyanin reductase activity
CY774_RS01450	COG1970	mechanosensitive ion channel activity
CY774_RS01455	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CY774_RS01470	COG2808	Putative FMN-binding domain
CY774_RS01475	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CY774_RS01480	COG0747	negative chemotaxis
CY774_RS01485	COG0657	acetylesterase activity
CY774_RS01495	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CY774_RS01500	COG2207	Transcriptional regulator
CY774_RS01505	COG0129	dihydroxy-acid dehydratase activity
CY774_RS01510	COG2814	Major facilitator Superfamily
CY774_RS01515	COG0583	DNA-binding transcription factor activity
CY774_RS01525	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
CY774_RS01595	COG1024	Enoyl-CoA hydratase
CY774_RS01600	COG1960	acyl-CoA dehydrogenase activity
CY774_RS01625	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CY774_RS01630	COG0352	thiamine-phosphate diphosphorylase activity
CY774_RS01645	COG1678	Uncharacterized ACR, COG1678
CY774_RS01650	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CY774_RS01655	COG0540	Belongs to the ATCase OTCase family
CY774_RS01670	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CY774_RS01680	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CY774_RS01715	COG1234	tRNA 3'-trailer cleavage
CY774_RS01735	COG3064	Membrane
CY774_RS01765	COG1683	Conserved Protein
CY774_RS01770	COG1120	ATPase activity
CY774_RS01775	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CY774_RS01780	COG4558	Periplasmic binding protein
CY774_RS01785	COG3720	iron ion transport
CY774_RS01795	COG3712	iron ion homeostasis
CY774_RS01800	COG1595	DNA-templated transcription, initiation
CY774_RS01835	COG1802	Transcriptional regulator
CY774_RS01845	COG3069	C4-dicarboxylate transmembrane transporter activity
CY774_RS01855	COG1012	belongs to the aldehyde dehydrogenase family
CY774_RS01890	COG2860	membrane
CY774_RS01895	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CY774_RS01900	COG0708	Exodeoxyribonuclease III
CY774_RS01905	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CY774_RS01910	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CY774_RS01915	COG0154	amidase activity
CY774_RS01920	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CY774_RS01925	COG1077	Cell shape determining protein MreB Mrl
CY774_RS01930	COG1792	Involved in formation and maintenance of cell shape
CY774_RS01940	COG0768	penicillin binding
CY774_RS01945	COG0772	Belongs to the SEDS family
CY774_RS01950	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CY774_RS01955	COG0471	metal ion transport
CY774_RS01960	COG1309	transcriptional regulator
CY774_RS01970	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CY774_RS01985	COG2823	Periplasmic or secreted lipoprotein
CY774_RS01990	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CY774_RS02005	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CY774_RS02025	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CY774_RS02035	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CY774_RS02055	COG0492	ferredoxin-NADP+ reductase activity
CY774_RS02065	COG3181	Tripartite tricarboxylate transporter family receptor
CY774_RS02070	COG1250	3-hydroxyacyl-CoA dehydrogenase
CY774_RS02070	COG1024	Enoyl-CoA hydratase
CY774_RS02075	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CY774_RS02080	COG0028	Belongs to the TPP enzyme family
CY774_RS02105	COG3181	Tripartite tricarboxylate transporter family receptor
CY774_RS02120	COG0697	spore germination
CY774_RS02150	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CY774_RS02155	COG0463	Glycosyl transferase, family 2
CY774_RS02170	COG0786	glutamate:sodium symporter activity
CY774_RS02180	COG2031	fatty acid transporter
CY774_RS02195	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CY774_RS02210	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CY774_RS02225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CY774_RS02235	COG1285	pathogenesis
CY774_RS02240	COG1253	flavin adenine dinucleotide binding
CY774_RS02245	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CY774_RS02250	COG1024	Enoyl-CoA hydratase
CY774_RS02255	COG3181	Tripartite tricarboxylate transporter family receptor
CY774_RS02260	COG0583	DNA-binding transcription factor activity
CY774_RS02265	COG1960	acyl-CoA dehydrogenase activity
CY774_RS02275	COG0183	Belongs to the thiolase family
CY774_RS02295	COG0583	DNA-binding transcription factor activity
CY774_RS02300	COG1278	Cold shock
CY774_RS02310	COG1802	Transcriptional regulator
CY774_RS02315	COG1012	belongs to the aldehyde dehydrogenase family
CY774_RS02320	COG2031	fatty acid transporter
CY774_RS02325	COG1017	nitric oxide dioxygenase activity
CY774_RS02325	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CY774_RS02330	COG0251	oxidation-reduction process
CY774_RS02350	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CY774_RS02360	COG0583	DNA-binding transcription factor activity
CY774_RS02365	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CY774_RS02380	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CY774_RS02385	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CY774_RS02390	COG0546	phosphoglycolate phosphatase activity
CY774_RS02400	COG1530	ribonuclease E activity
CY774_RS02420	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CY774_RS02425	COG0159	tryptophan synthase activity
CY774_RS02430	COG0133	tryptophan synthase activity
CY774_RS02440	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CY774_RS02445	COG3228	Belongs to the MtfA family
CY774_RS02455	COG0251	oxidation-reduction process
CY774_RS02460	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CY774_RS02465	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CY774_RS02480	COG2878	Part of a membrane complex involved in electron transport
CY774_RS02485	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CY774_RS02520	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CY774_RS02540	COG1268	BioY protein
CY774_RS02545	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CY774_RS02550	COG1122	ATPase activity
CY774_RS02555	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CY774_RS02570	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CY774_RS02575	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CY774_RS02585	COG1196	nuclear chromosome segregation
CY774_RS02590	COG0477	Major facilitator Superfamily
CY774_RS02595	COG1573	uracil-dna glycosylase
CY774_RS02600	COG1214	PFAM Peptidase M22, glycoprotease
CY774_RS02620	COG0450	alkyl hydroperoxide reductase
CY774_RS02625	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CY774_RS02635	COG2223	nitrite transmembrane transporter activity
CY774_RS02645	COG2186	Transcriptional regulator
CY774_RS02665	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CY774_RS02675	COG0583	DNA-binding transcription factor activity
CY774_RS02685	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CY774_RS02690	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CY774_RS02695	COG0137	argininosuccinate synthase activity
CY774_RS02700	COG3158	transport of potassium into the cell
CY774_RS02705	COG0642	Histidine kinase
CY774_RS02735	COG0776	regulation of translation
CY774_RS02740	COG3128	pkhd-type hydroxylase
CY774_RS02750	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CY774_RS02755	COG0557	exoribonuclease II activity
CY774_RS02780	COG0679	Auxin Efflux Carrier
CY774_RS02785	COG2391	methyltransferase activity
CY774_RS02790	COG0069	glutamate synthase activity
CY774_RS02800	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CY774_RS02810	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
CY774_RS02850	COG3706	GGDEF domain
CY774_RS02875	COG1053	succinate dehydrogenase
CY774_RS02880	COG0583	DNA-binding transcription factor activity
CY774_RS02895	COG1053	succinate dehydrogenase
CY774_RS02915	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CY774_RS02920	COG0459	protein refolding
CY774_RS02925	COG3468	outer membrane autotransporter barrel domain protein
CY774_RS02940	COG1252	NADH dehydrogenase
CY774_RS02945	COG0284	orotidine-5'-phosphate decarboxylase activity
CY774_RS02950	COG1546	Belongs to the CinA family
CY774_RS02950	COG1058	Belongs to the CinA family
CY774_RS02955	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CY774_RS02965	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CY774_RS02970	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CY774_RS03010	COG3639	organic phosphonate transmembrane transporter activity
CY774_RS03015	COG3639	organic phosphonate transmembrane transporter activity
CY774_RS03035	COG0742	ribosomal rna small subunit methyltransferase
CY774_RS03040	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CY774_RS03045	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CY774_RS03050	COG3135	benzoate transporter
CY774_RS03065	COG0640	Transcriptional regulator
CY774_RS03095	COG4172	Belongs to the ABC transporter superfamily
CY774_RS03100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CY774_RS03105	COG0601	transmembrane transport
CY774_RS03115	COG0280	phosphate acetyltransferase
CY774_RS03115	COG0281	malic enzyme
CY774_RS03175	COG0583	DNA-binding transcription factor activity
CY774_RS03190	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CY774_RS03195	COG0167	dihydroorotate dehydrogenase activity
CY774_RS03215	COG1414	Transcriptional regulator
CY774_RS03220	COG1546	Belongs to the CinA family
CY774_RS03220	COG1058	Belongs to the CinA family
CY774_RS03240	COG0513	Belongs to the DEAD box helicase family
CY774_RS03270	COG0429	hydrolase of the alpha beta-hydrolase fold
CY774_RS03275	COG4783	chaperone-mediated protein folding
CY774_RS03290	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CY774_RS03315	COG0006	proline dipeptidase activity
CY774_RS03325	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CY774_RS03345	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CY774_RS03350	COG0632	four-way junction helicase activity
CY774_RS03365	COG2255	four-way junction helicase activity
CY774_RS03370	COG0514	ATP-dependent DNA helicase (RecQ)
CY774_RS03385	COG0288	reversible hydration of carbon dioxide
CY774_RS03390	COG0154	amidase activity
CY774_RS03400	COG4211	Belongs to the binding-protein-dependent transport system permease family
CY774_RS03430	COG1464	Belongs to the NlpA lipoprotein family
CY774_RS03570	COG1196	nuclear chromosome segregation
CY774_RS03645	COG2135	peptidase activity
CY774_RS03660	COG0494	nUDIX hydrolase
CY774_RS03665	COG0442	prolyl-tRNA aminoacylation
CY774_RS03670	COG0824	Thioesterase
CY774_RS03675	COG0811	peptide transport
CY774_RS03680	COG0848	biopolymer transport protein
CY774_RS03690	COG0823	Involved in the tonB-independent uptake of proteins
CY774_RS03705	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CY774_RS03710	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CY774_RS03745	COG0700	Nucleoside recognition
CY774_RS03750	COG0469	pyruvate kinase activity
CY774_RS03755	COG1929	Belongs to the glycerate kinase type-1 family
CY774_RS03760	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CY774_RS03765	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CY774_RS03770	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CY774_RS03780	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CY774_RS03790	COG2154	pterin-4-alpha-carbinolamine dehydratase
CY774_RS03815	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CY774_RS03820	COG0154	amidase activity
CY774_RS03830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CY774_RS03835	COG0601	transmembrane transport
CY774_RS03840	COG0747	negative chemotaxis
CY774_RS03860	COG0019	diaminopimelate decarboxylase activity
CY774_RS03875	COG2353	YceI-like domain
CY774_RS03880	COG4774	siderophore transport
CY774_RS03885	COG3712	iron ion homeostasis
CY774_RS03930	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CY774_RS03935	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CY774_RS03940	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CY774_RS03945	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CY774_RS03955	COG0142	geranyltranstransferase activity
CY774_RS03965	COG0583	DNA-binding transcription factor activity
CY774_RS03975	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
CY774_RS03980	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CY774_RS04000	COG2994	toxin metabolic process
CY774_RS04010	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CY774_RS04015	COG2274	protein secretion by the type I secretion system
CY774_RS04020	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CY774_RS04025	COG1538	Outer membrane efflux protein
CY774_RS04045	COG0765	amino acid transport
CY774_RS04050	COG1126	abc transporter atp-binding protein
CY774_RS04070	COG1028	Short-chain dehydrogenase reductase Sdr
CY774_RS04080	COG1802	Transcriptional regulator
CY774_RS04090	COG1802	Transcriptional regulator
CY774_RS04100	COG0318	PFAM AMP-dependent synthetase and ligase
CY774_RS04110	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CY774_RS04130	COG0028	Belongs to the TPP enzyme family
CY774_RS04150	COG0308	aminopeptidase N
CY774_RS04155	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CY774_RS04175	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CY774_RS04180	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CY774_RS04185	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CY774_RS04190	COG0560	Phosphoserine phosphatase
CY774_RS04195	COG0583	DNA-binding transcription factor activity
CY774_RS04200	COG3181	Tripartite tricarboxylate transporter family receptor
CY774_RS04205	COG0028	Belongs to the TPP enzyme family
CY774_RS04220	COG4774	siderophore transport
CY774_RS04225	COG4774	siderophore transport
CY774_RS04235	COG1007	ATP synthesis coupled electron transport
CY774_RS04250	COG0713	ATP synthesis coupled electron transport
CY774_RS04260	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CY774_RS04265	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CY774_RS04270	COG1034	ATP synthesis coupled electron transport
CY774_RS04280	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CY774_RS04285	COG0649	NAD binding
CY774_RS04290	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CY774_RS04295	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CY774_RS04300	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CY774_RS04305	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CY774_RS04335	COG0671	phosphoesterase, PA-phosphatase related
CY774_RS04345	COG1597	lipid kinase activity
CY774_RS04350	COG0583	DNA-binding transcription factor activity
CY774_RS04355	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CY774_RS04365	COG1733	regulation of RNA biosynthetic process
CY774_RS04370	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CY774_RS04375	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CY774_RS04390	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
CY774_RS04410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CY774_RS04430	COG3608	succinylglutamate desuccinylase aspartoacylase
CY774_RS04435	COG0626	cystathionine gamma-synthase activity
CY774_RS04440	COG0583	DNA-binding transcription factor activity
CY774_RS04475	COG3799	methylaspartate ammonia-lyase activity
CY774_RS04485	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CY774_RS04495	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CY774_RS04500	COG0149	triose-phosphate isomerase activity
CY774_RS04520	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CY774_RS04535	COG1185	polyribonucleotide nucleotidyltransferase activity
CY774_RS04540	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CY774_RS04555	COG1183	phosphatidylcholine synthase activity
CY774_RS04560	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CY774_RS04565	COG0440	acetolactate synthase activity
CY774_RS04570	COG0028	Belongs to the TPP enzyme family
CY774_RS04585	COG5265	(ABC) transporter
CY774_RS04590	COG0500	methyltransferase
CY774_RS04610	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CY774_RS04630	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CY774_RS04640	COG0511	ligase activity, forming carbon-carbon bonds
CY774_RS04665	COG2188	Transcriptional regulator
CY774_RS04670	COG0439	Biotin carboxylase
CY774_RS04720	COG5265	(ABC) transporter
CY774_RS04730	COG0667	Aldo Keto reductase
CY774_RS04745	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CY774_RS04785	COG0583	DNA-binding transcription factor activity
CY774_RS04820	COG2814	Major facilitator Superfamily
CY774_RS04830	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CY774_RS04845	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CY774_RS04855	COG0287	Prephenate dehydrogenase
CY774_RS04860	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CY774_RS04865	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CY774_RS04885	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CY774_RS04890	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CY774_RS04895	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CY774_RS04900	COG1555	photosystem II stabilization
CY774_RS04900	COG1596	polysaccharide export
CY774_RS04915	COG2951	lytic endotransglycosylase activity
CY774_RS04920	COG0123	including yeast histone deacetylase and acetoin utilization protein
CY774_RS04935	COG1960	acyl-CoA dehydrogenase activity
CY774_RS04940	COG0450	alkyl hydroperoxide reductase
CY774_RS04960	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CY774_RS04995	COG0335	large ribosomal subunit rRNA binding
CY774_RS05010	COG0667	Aldo Keto reductase
CY774_RS05025	COG3161	chorismate lyase activity
CY774_RS05030	COG1187	pseudouridine synthase activity
CY774_RS05060	COG1999	signal sequence binding
CY774_RS05065	COG0339	signal peptide processing
CY774_RS05070	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CY774_RS05075	COG4566	intracellular signal transduction
CY774_RS05085	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CY774_RS05090	COG0508	dehydrogenase complex catalyzes the overall conversion of
CY774_RS05095	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CY774_RS05100	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CY774_RS05110	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CY774_RS05115	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CY774_RS05120	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CY774_RS05125	COG0126	phosphoglycerate kinase activity
CY774_RS05130	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CY774_RS05135	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CY774_RS05150	COG0625	glutathione transferase activity
CY774_RS05180	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CY774_RS05190	COG0521	Mo-molybdopterin cofactor biosynthetic process
CY774_RS05200	COG0739	heme binding
CY774_RS05210	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CY774_RS05245	COG0745	RESPONSE REGULATOR receiver
CY774_RS05260	COG0840	transmembrane signaling receptor activity
CY774_RS05270	COG2201	protein-glutamate methylesterase activity
CY774_RS05275	COG0745	RESPONSE REGULATOR receiver
CY774_RS05280	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CY774_RS05305	COG0667	Aldo Keto reductase
CY774_RS05315	COG4535	Mg2 and Co2 transporter CorC
CY774_RS05320	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CY774_RS05325	COG1702	phosphate starvation-inducible protein PhoH
CY774_RS05330	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CY774_RS05345	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CY774_RS05350	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CY774_RS05355	COG1862	Preprotein translocase
CY774_RS05360	COG0343	queuine tRNA-ribosyltransferase activity
CY774_RS05365	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CY774_RS05370	COG2027	D-alanyl-D-alanine carboxypeptidase
CY774_RS05375	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CY774_RS05385	COG3468	outer membrane autotransporter barrel domain protein
CY774_RS05390	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CY774_RS05390	COG1648	precorrin-2 dehydrogenase activity
CY774_RS05415	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CY774_RS05420	COG0741	lytic transglycosylase activity
CY774_RS05430	COG0436	Aminotransferase
CY774_RS05440	COG0280	phosphate acetyltransferase
CY774_RS05440	COG0281	malic enzyme
CY774_RS05450	COG2732	(Barnase) inhibitor
CY774_RS05465	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CY774_RS05490	COG0248	Ppx GppA phosphatase
CY774_RS05500	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CY774_RS05510	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CY774_RS05515	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CY774_RS05520	COG1534	Rna-binding protein
CY774_RS05550	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CY774_RS05565	COG1295	ribonuclease BN
CY774_RS05575	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CY774_RS05580	COG0745	RESPONSE REGULATOR receiver
CY774_RS05585	COG2205	protein histidine kinase activity
CY774_RS05620	COG1022	Amp-dependent synthetase and ligase
CY774_RS05635	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CY774_RS05640	COG1028	Short-chain dehydrogenase reductase Sdr
CY774_RS05650	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CY774_RS05665	COG1136	(ABC) transporter
CY774_RS05670	COG0084	hydrolase, TatD family'
CY774_RS05695	COG0658	competence protein
CY774_RS05695	COG2333	competence protein COMEC
CY774_RS05705	COG0613	PHP domain protein
CY774_RS05725	COG3539	Fimbrial protein
CY774_RS05730	COG0280	phosphate acetyltransferase
CY774_RS05730	COG0281	malic enzyme
CY774_RS05740	COG1522	sequence-specific DNA binding
CY774_RS05750	COG0567	Dehydrogenase, E1 component
CY774_RS05755	COG0508	dehydrogenase complex catalyzes the overall conversion of
CY774_RS05760	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CY774_RS05765	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CY774_RS05770	COG1028	Short-chain dehydrogenase reductase Sdr
CY774_RS05775	COG0583	DNA-binding transcription factor activity
CY774_RS05785	COG3181	Tripartite tricarboxylate transporter family receptor
CY774_RS05810	COG0180	Tryptophanyl-tRNA synthetase
CY774_RS05815	COG2183	response to ionizing radiation
CY774_RS05820	COG1199	ATP-dependent helicase activity
CY774_RS05830	COG0564	pseudouridine synthase activity
CY774_RS05840	COG3243	poly(R)-hydroxyalkanoic acid synthase
CY774_RS05845	COG1028	Short-chain dehydrogenase reductase Sdr
CY774_RS05850	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
CY774_RS05865	COG0672	)-iron permease
CY774_RS05905	COG0583	DNA-binding transcription factor activity
CY774_RS05915	COG2814	Major facilitator Superfamily
CY774_RS05930	COG1619	proteins homologs of microcin C7 resistance protein MccF
CY774_RS05945	COG2084	Dehydrogenase
CY774_RS05950	COG3181	Tripartite tricarboxylate transporter family receptor
CY774_RS05975	COG2988	succinylglutamate desuccinylase activity
CY774_RS06005	COG0765	amino acid transport
CY774_RS06010	COG0765	amino acid transport
CY774_RS06015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CY774_RS06050	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CY774_RS06055	COG1595	DNA-templated transcription, initiation
CY774_RS06065	COG3530	Putative quorum-sensing-regulated virulence factor
CY774_RS06070	COG0494	nUDIX hydrolase
CY774_RS06085	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CY774_RS06090	COG0542	response to heat
CY774_RS06110	COG3468	outer membrane autotransporter barrel domain protein
CY774_RS06120	COG5441	Belongs to the UPF0261 family
CY774_RS06125	COG5564	TIM-barrel signal transduction protein
CY774_RS06140	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CY774_RS06155	COG1477	protein flavinylation
CY774_RS06175	COG1131	(ABC) transporter
CY774_RS06180	COG0842	Transport permease protein
CY774_RS06190	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CY774_RS06195	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CY774_RS06195	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CY774_RS06200	COG1562	ergosterol biosynthetic process
CY774_RS06205	COG1562	ergosterol biosynthetic process
CY774_RS06210	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CY774_RS06215	COG1028	Short-chain dehydrogenase reductase Sdr
CY774_RS06235	COG2304	oxidoreductase activity
CY774_RS06255	COG0534	Mate efflux family protein
CY774_RS06265	COG0254	rRNA binding
CY774_RS06270	COG3483	tryptophan 2,3-dioxygenase activity
CY774_RS06275	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CY774_RS06280	COG2003	Belongs to the UPF0758 family
CY774_RS06285	COG1047	Peptidyl-prolyl cis-trans
CY774_RS06290	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CY774_RS06295	COG0625	glutathione transferase activity
CY774_RS06315	COG0523	cobalamin synthesis protein
CY774_RS06325	COG0583	DNA-binding transcription factor activity
CY774_RS06335	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CY774_RS06340	COG1187	pseudouridine synthase activity
CY774_RS06345	COG0779	Required for maturation of 30S ribosomal subunits
CY774_RS06350	COG2251	uridine kinase activity
CY774_RS06350	COG0195	Participates in both transcription termination and antitermination
CY774_RS06355	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CY774_RS06360	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CY774_RS06365	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CY774_RS06385	COG1611	Belongs to the LOG family
CY774_RS06400	COG0412	Dienelactone hydrolase
CY774_RS06405	COG1283	sodium-dependent phosphate transmembrane transporter activity
CY774_RS06410	COG1760	l-serine dehydratase
CY774_RS06415	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CY774_RS06420	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CY774_RS06430	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CY774_RS06455	COG2311	Membrane
CY774_RS06480	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CY774_RS06500	COG0559	Belongs to the binding-protein-dependent transport system permease family
CY774_RS06520	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CY774_RS06530	COG1653	transport
CY774_RS06535	COG1175	transmembrane transport
CY774_RS06540	COG0395	ABC-type sugar transport system, permease component
CY774_RS06545	COG3842	ATPase activity
CY774_RS06570	COG2363	Small membrane protein
CY774_RS06585	COG1464	Belongs to the NlpA lipoprotein family
CY774_RS06595	COG0688	phosphatidylethanolamine metabolic process
CY774_RS06610	COG0095	Lipoate-protein ligase
CY774_RS06625	COG0625	glutathione transferase activity
CY774_RS06630	COG0386	Belongs to the glutathione peroxidase family
CY774_RS06650	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CY774_RS06685	COG2259	Doxx family
CY774_RS06700	COG0667	Aldo Keto reductase
CY774_RS06730	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CY774_RS06750	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CY774_RS06760	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CY774_RS06810	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CY774_RS06815	COG3568	Endonuclease Exonuclease Phosphatase
CY774_RS06825	COG1695	Transcriptional regulator
CY774_RS06845	COG0583	DNA-binding transcription factor activity
CY774_RS06860	COG1802	Transcriptional regulator
CY774_RS06870	COG3181	Tripartite tricarboxylate transporter family receptor
CY774_RS06880	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CY774_RS06895	COG0066	3-isopropylmalate dehydratase activity
CY774_RS06905	COG3181	Tripartite tricarboxylate transporter family receptor
CY774_RS06910	COG4948	Mandelate Racemase Muconate Lactonizing
CY774_RS06925	COG1126	abc transporter atp-binding protein
CY774_RS06930	COG0765	amino acid transport
CY774_RS06935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CY774_RS06975	COG1815	bacterial-type flagellum-dependent cell motility
CY774_RS06980	COG1558	bacterial-type flagellum-dependent cell motility
CY774_RS06990	COG1749	Flagellar hook protein flgE
CY774_RS07005	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CY774_RS07010	COG1706	bacterial-type flagellum-dependent cell motility
CY774_RS07020	COG1256	bacterial-type flagellum assembly
CY774_RS07030	COG0840	transmembrane signaling receptor activity
CY774_RS07035	COG0840	transmembrane signaling receptor activity
CY774_RS07040	COG0840	transmembrane signaling receptor activity
CY774_RS07060	COG1338	Plays a role in the flagellum-specific transport system
CY774_RS07080	COG1580	Controls the rotational direction of flagella during chemotaxis
CY774_RS07105	COG1157	protein secretion by the type III secretion system
CY774_RS07115	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CY774_RS07125	COG1677	Flagellar hook-basal body complex protein FliE
CY774_RS07135	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CY774_RS07170	COG0285	dihydrofolate synthase activity
CY774_RS07200	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CY774_RS07205	COG0024	Methionine aminopeptidase
CY774_RS07210	COG0052	Belongs to the universal ribosomal protein uS2 family
CY774_RS07215	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CY774_RS07220	COG0528	UMP kinase activity
CY774_RS07225	COG0233	cytoplasmic translational termination
CY774_RS07230	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CY774_RS07240	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CY774_RS07245	COG0750	zinc metalloprotease
CY774_RS07250	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CY774_RS07255	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CY774_RS07260	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CY774_RS07265	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CY774_RS07275	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CY774_RS07280	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CY774_RS07285	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CY774_RS07290	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CY774_RS07300	COG0519	Catalyzes the synthesis of GMP from XMP
CY774_RS07300	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CY774_RS07315	COG0330	HflC and HflK could
CY774_RS07320	COG3706	GGDEF domain
CY774_RS07325	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CY774_RS07335	COG2867	negative regulation of translational initiation
CY774_RS07345	COG1960	acyl-CoA dehydrogenase activity
CY774_RS07350	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CY774_RS07385	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CY774_RS07390	COG0505	Belongs to the CarA family
CY774_RS07395	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CY774_RS07405	COG0406	alpha-ribazole phosphatase activity
CY774_RS07415	COG3842	ATPase activity
CY774_RS07435	COG5001	Diguanylate cyclase
CY774_RS07440	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CY774_RS07450	COG1763	Mo-molybdopterin cofactor biosynthetic process
CY774_RS07455	COG0303	'Molybdopterin
CY774_RS07460	COG0746	molybdenum cofactor guanylyltransferase activity
CY774_RS07465	COG0489	protein tyrosine kinase activity
CY774_RS07495	COG0243	molybdopterin cofactor binding
CY774_RS07495	COG3383	formate dehydrogenase (NAD+) activity
CY774_RS07530	COG1122	ATPase activity
CY774_RS07540	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CY774_RS07545	COG0066	3-isopropylmalate dehydratase activity
CY774_RS07550	COG0473	3-isopropylmalate dehydrogenase activity
CY774_RS07555	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CY774_RS07565	COG0101	tRNA pseudouridine synthase activity
CY774_RS07570	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CY774_RS07585	COG0135	phosphoribosylanthranilate isomerase activity
CY774_RS07600	COG3022	response to hydroperoxide
CY774_RS07640	COG2197	response regulator
CY774_RS07645	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CY774_RS07650	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CY774_RS07655	COG0189	ligase activity
CY774_RS07665	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CY774_RS07670	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CY774_RS07685	COG2423	ornithine cyclodeaminase activity
CY774_RS07695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CY774_RS07700	COG0765	amino acid transport
CY774_RS07705	COG0765	amino acid transport
CY774_RS07710	COG1126	abc transporter atp-binding protein
CY774_RS07765	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CY774_RS07775	COG2944	sequence-specific DNA binding
CY774_RS07785	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CY774_RS07790	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CY774_RS07795	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CY774_RS07800	COG0009	L-threonylcarbamoyladenylate synthase
CY774_RS07805	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CY774_RS07810	COG1414	Transcriptional regulator
CY774_RS07825	COG0765	amino acid transport
CY774_RS07830	COG1126	abc transporter atp-binding protein
CY774_RS07835	COG0028	Belongs to the TPP enzyme family
CY774_RS07850	COG0028	Belongs to the TPP enzyme family
CY774_RS07855	COG0583	DNA-binding transcription factor activity
CY774_RS07860	COG4974	Belongs to the 'phage' integrase family
CY774_RS07865	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CY774_RS07870	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CY774_RS07885	COG1686	Belongs to the peptidase S11 family
CY774_RS07895	COG2814	Major facilitator Superfamily
CY774_RS07905	COG1074	ATP-dependent DNA helicase activity
CY774_RS07915	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CY774_RS07920	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CY774_RS07925	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CY774_RS07945	COG2321	neutral zinc metallopeptidase
CY774_RS07950	COG0009	L-threonylcarbamoyladenylate synthase
CY774_RS07995	COG3360	Dodecin
CY774_RS08000	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CY774_RS08005	COG2850	peptidyl-arginine hydroxylation
CY774_RS08010	COG3539	Fimbrial protein
CY774_RS08015	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CY774_RS08020	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CY774_RS08035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CY774_RS08040	COG0765	amino acid transport
CY774_RS08045	COG1126	abc transporter atp-binding protein
CY774_RS08050	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CY774_RS08055	COG1758	RNA polymerase activity
CY774_RS08060	COG0194	GDP metabolic process
CY774_RS08065	COG3258	Cytochrome c
CY774_RS08070	COG2863	cytochrome
CY774_RS08075	COG1028	Short-chain dehydrogenase reductase Sdr
CY774_RS08080	COG0791	NLP P60 protein
CY774_RS08085	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CY774_RS08105	COG1561	YicC-like family, N-terminal region
CY774_RS08110	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CY774_RS08130	COG2200	EAL domain
CY774_RS08130	COG2199	diguanylate cyclase activity
CY774_RS08135	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CY774_RS08145	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CY774_RS08150	COG0174	glutamine synthetase
CY774_RS08160	COG2204	response regulator
CY774_RS08165	COG0583	DNA-binding transcription factor activity
CY774_RS08170	COG1741	Belongs to the pirin family
CY774_RS08175	COG1741	Belongs to the pirin family
CY774_RS08185	COG3842	ATPase activity
CY774_RS08190	COG1178	ABC-type Fe3 transport system permease component
CY774_RS08195	COG1840	ABC-type Fe3 transport system, periplasmic component
CY774_RS08205	COG0583	DNA-binding transcription factor activity
CY774_RS08215	COG0656	L-ascorbic acid biosynthetic process
CY774_RS08230	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CY774_RS08235	COG0583	DNA-binding transcription factor activity
CY774_RS08250	COG0783	Belongs to the Dps family
CY774_RS08270	COG0463	Glycosyl transferase, family 2
CY774_RS08290	COG0438	transferase activity, transferring glycosyl groups
CY774_RS08305	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CY774_RS08330	COG0300	oxidoreductase activity
CY774_RS08375	COG0861	Integral membrane protein TerC family
CY774_RS08380	COG1028	Short-chain dehydrogenase reductase Sdr
CY774_RS08400	COG0714	Associated with various cellular activities
CY774_RS08435	COG3119	arylsulfatase activity
CY774_RS08460	COG2197	response regulator
CY774_RS08470	COG2944	sequence-specific DNA binding
CY774_RS08480	COG0625	glutathione transferase activity
CY774_RS08510	COG0179	Fumarylacetoacetate (FAA) hydrolase
CY774_RS08515	COG1028	Short-chain dehydrogenase reductase Sdr
CY774_RS08560	COG0431	NADPH-dependent FMN reductase
CY774_RS08590	COG1028	Short-chain dehydrogenase reductase Sdr
CY774_RS08595	COG0583	DNA-binding transcription factor activity
CY774_RS08615	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CY774_RS08615	COG2111	Na H antiporter
CY774_RS08620	COG1006	Multisubunit Na H antiporter MnhC subunit
CY774_RS08625	COG0651	ATP synthesis coupled electron transport
CY774_RS08630	COG1863	multisubunit Na H antiporter MnhE subunit
CY774_RS08635	COG2212	antiporter activity
CY774_RS08660	COG0590	tRNA wobble adenosine to inosine editing
CY774_RS08665	COG1619	proteins homologs of microcin C7 resistance protein MccF
CY774_RS08670	COG1024	Enoyl-CoA hydratase
CY774_RS08685	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CY774_RS08690	COG0488	(ABC) transporter
CY774_RS08725	COG1017	nitric oxide dioxygenase activity
CY774_RS08725	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CY774_RS08730	COG1959	2 iron, 2 sulfur cluster binding
CY774_RS08735	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CY774_RS08755	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CY774_RS08760	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CY774_RS08765	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CY774_RS08770	COG0084	hydrolase, TatD family'
CY774_RS08785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CY774_RS08795	COG1126	abc transporter atp-binding protein
CY774_RS08805	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CY774_RS08820	COG0028	Belongs to the TPP enzyme family
CY774_RS08830	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CY774_RS08830	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CY774_RS08840	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CY774_RS08890	COG4336	lyase activity
CY774_RS08900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CY774_RS08900	COG2205	protein histidine kinase activity
CY774_RS08905	COG2197	response regulator
CY774_RS08910	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CY774_RS08910	COG3064	Membrane
CY774_RS08910	COG3210	domain, Protein
CY774_RS08920	COG3121	Chaperone
CY774_RS08925	COG3188	usher protein
CY774_RS08930	COG3539	Fimbrial protein
CY774_RS08935	COG2831	hemolysin activation secretion protein
CY774_RS08950	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CY774_RS09000	COG0668	transmembrane transport
CY774_RS09020	COG0483	inositol monophosphate 1-phosphatase activity
CY774_RS09025	COG1253	flavin adenine dinucleotide binding
CY774_RS09030	COG1968	undecaprenyl-diphosphatase activity
CY774_RS09035	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CY774_RS09050	COG0215	cysteine-tRNA ligase activity
CY774_RS09060	COG0825	malonyl-CoA metabolic process
CY774_RS09070	COG0037	tRNA processing
CY774_RS09075	COG0527	aspartate kinase activity
CY774_RS09100	COG1250	3-hydroxyacyl-CoA dehydrogenase
CY774_RS09105	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CY774_RS09105	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CY774_RS09120	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CY774_RS09125	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
CY774_RS09130	COG1028	Short-chain dehydrogenase reductase Sdr
CY774_RS09140	COG0583	DNA-binding transcription factor activity
CY774_RS09165	COG3842	ATPase activity
CY774_RS09175	COG1902	pentaerythritol trinitrate reductase activity
CY774_RS09175	COG0446	pyridine nucleotide-disulphide oxidoreductase
CY774_RS09180	COG1414	Transcriptional regulator
CY774_RS09185	COG1832	CoA-binding protein
CY774_RS09195	COG0251	oxidation-reduction process
CY774_RS09220	COG1902	pentaerythritol trinitrate reductase activity
CY774_RS09230	COG1215	transferase activity, transferring glycosyl groups
CY774_RS09235	COG1649	PFAM Uncharacterised BCR, COG1649
CY774_RS09235	COG0726	polysaccharide deacetylase
CY774_RS09255	COG1846	Transcriptional regulator
CY774_RS09260	COG2197	response regulator
CY774_RS09275	COG0166	Belongs to the GPI family
CY774_RS09280	COG1045	serine acetyltransferase
CY774_RS09290	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CY774_RS09295	COG0483	inositol monophosphate 1-phosphatase activity
CY774_RS09300	COG1012	belongs to the aldehyde dehydrogenase family
CY774_RS09305	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CY774_RS09320	COG0210	DNA helicase
CY774_RS09325	COG0598	Magnesium transport protein CorA
CY774_RS09335	COG0747	negative chemotaxis
CY774_RS09340	COG0601	transmembrane transport
CY774_RS09345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CY774_RS09350	COG4172	Belongs to the ABC transporter superfamily
CY774_RS09355	COG1846	Transcriptional regulator
CY774_RS09410	COG4964	Belongs to the GSP D family
CY774_RS09450	COG2204	response regulator
CY774_RS09465	COG1595	DNA-templated transcription, initiation
CY774_RS09475	COG3474	cytochrome
CY774_RS09480	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CY774_RS09495	COG3384	dioxygenase
CY774_RS09500	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CY774_RS09530	COG2885	chlorophyll binding
CY774_RS09565	COG0697	spore germination
CY774_RS09570	COG0730	response to heat
CY774_RS09590	COG0583	DNA-binding transcription factor activity
CY774_RS09595	COG0427	acetyl-CoA hydrolase
CY774_RS09650	COG1250	3-hydroxyacyl-CoA dehydrogenase
CY774_RS09655	COG0154	amidase activity
CY774_RS09665	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CY774_RS09680	COG0495	leucyl-tRNA aminoacylation
CY774_RS09685	COG2814	Major facilitator Superfamily
CY774_RS09720	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CY774_RS09725	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CY774_RS09730	COG2814	Major facilitator Superfamily
CY774_RS09750	COG4176	ABC-type proline glycine betaine transport system permease component
CY774_RS09760	COG1942	4-Oxalocrotonate Tautomerase
CY774_RS09765	COG0183	Belongs to the thiolase family
CY774_RS09775	COG1802	Transcriptional regulator
CY774_RS09785	COG1024	Enoyl-CoA hydratase
CY774_RS09800	COG2032	superoxide dismutase activity
CY774_RS09815	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CY774_RS09840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CY774_RS09845	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CY774_RS09855	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CY774_RS09860	COG0736	holo-[acyl-carrier-protein] synthase activity
CY774_RS09865	COG1472	Belongs to the glycosyl hydrolase 3 family
CY774_RS09870	COG0322	excinuclease ABC activity
CY774_RS09875	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CY774_RS09885	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CY774_RS09885	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CY774_RS09890	COG2224	Isocitrate lyase
CY774_RS09910	COG0559	Belongs to the binding-protein-dependent transport system permease family
CY774_RS09920	COG4638	Rieske (2fe-2S)
CY774_RS09930	COG1024	Enoyl-CoA hydratase
CY774_RS09940	COG0633	Ferredoxin
CY774_RS09945	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CY774_RS09960	COG0183	Belongs to the thiolase family
CY774_RS09975	COG0583	DNA-binding transcription factor activity
CY774_RS10005	COG2346	COG2346, Truncated hemoglobins
CY774_RS10135	COG2207	Transcriptional regulator
CY774_RS10185	COG1132	(ABC) transporter
CY774_RS10210	COG0659	secondary active sulfate transmembrane transporter activity
CY774_RS10240	COG2169	Transcriptional regulator
CY774_RS10245	COG5507	3-demethylubiquinone-9 3-methyltransferase
CY774_RS10250	COG0384	phenazine biosynthesis protein PhzF
CY774_RS10255	COG0583	DNA-binding transcription factor activity
CY774_RS10260	COG2733	membrane
CY774_RS10275	COG1012	belongs to the aldehyde dehydrogenase family
CY774_RS10280	COG3284	Transcriptional regulator
CY774_RS10305	COG1380	Effector of murein hydrolase LrgA
CY774_RS10310	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CY774_RS10310	COG4106	trans-aconitate 2-methyltransferase activity
CY774_RS10320	COG0156	8-amino-7-oxononanoate synthase activity
CY774_RS10390	COG1131	(ABC) transporter
CY774_RS10395	COG0842	Transport permease protein
CY774_RS10400	COG0628	permease
CY774_RS10435	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CY774_RS10450	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CY774_RS10455	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CY774_RS10460	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CY774_RS10465	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CY774_RS10470	COG0330	HflC and HflK could
CY774_RS10475	COG0330	HflC and HflK could
CY774_RS10480	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CY774_RS10485	COG1923	regulation of RNA biosynthetic process
CY774_RS10490	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CY774_RS10495	COG1160	GTP binding
CY774_RS10500	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CY774_RS10505	COG2976	Protein conserved in bacteria
CY774_RS10510	COG0124	histidyl-tRNA synthetase
CY774_RS10515	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CY774_RS10525	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CY774_RS10530	COG0105	UTP biosynthetic process
CY774_RS10535	COG0525	valine-tRNA ligase activity
CY774_RS10550	COG0642	Histidine kinase
CY774_RS10575	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CY774_RS10580	COG0336	Belongs to the RNA methyltransferase TrmD family
CY774_RS10585	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CY774_RS10590	COG0228	four-way junction DNA binding
CY774_RS10600	COG0425	Belongs to the sulfur carrier protein TusA family
CY774_RS10605	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CY774_RS10650	COG0154	amidase activity
CY774_RS10655	COG4172	Belongs to the ABC transporter superfamily
CY774_RS10660	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CY774_RS10665	COG0601	transmembrane transport
CY774_RS10670	COG0747	negative chemotaxis
CY774_RS10700	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CY774_RS10710	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CY774_RS10730	COG3395	kinase activity
CY774_RS10745	COG1024	Enoyl-CoA hydratase
CY774_RS10765	COG0633	Ferredoxin
CY774_RS10770	COG0443	Heat shock 70 kDa protein
CY774_RS10775	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CY774_RS10780	COG0316	Belongs to the HesB IscA family
CY774_RS10785	COG0822	iron-sulfur transferase activity
CY774_RS10790	COG1104	cysteine desulfurase activity
CY774_RS10800	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CY774_RS10805	COG0556	nucleotide-excision repair
CY774_RS10815	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CY774_RS10845	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CY774_RS10865	COG1028	Short-chain dehydrogenase reductase Sdr
CY774_RS10870	COG0183	Belongs to the thiolase family
CY774_RS10880	COG1024	Enoyl-CoA hydratase
CY774_RS10895	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CY774_RS10900	COG0583	DNA-binding transcription factor activity
CY774_RS10905	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CY774_RS10910	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CY774_RS10915	COG0740	serine-type endopeptidase activity
CY774_RS10920	COG0544	peptidyl-prolyl cis-trans isomerase activity
CY774_RS10930	COG1278	Cold shock
CY774_RS10940	COG1278	Cold shock
CY774_RS10975	COG2171	N-acyltransferase activity
CY774_RS10980	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CY774_RS10985	COG2890	protein-(glutamine-N5) methyltransferase activity
CY774_RS10990	COG0488	(ABC) transporter
CY774_RS10995	COG4771	TonB-dependent receptor
CY774_RS11000	COG0210	DNA helicase
CY774_RS11020	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CY774_RS11025	COG0196	riboflavin kinase activity
CY774_RS11030	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CY774_RS11035	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CY774_RS11040	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CY774_RS11050	COG1522	sequence-specific DNA binding
CY774_RS11070	COG2951	lytic endotransglycosylase activity
CY774_RS11075	COG2833	Protein of unknown function (DUF455)
CY774_RS11095	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CY774_RS11095	COG0189	ligase activity
CY774_RS11100	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CY774_RS11100	COG1181	Belongs to the D-alanine--D-alanine ligase family
CY774_RS11105	COG3237	CsbD-like
CY774_RS11115	COG2823	Periplasmic or secreted lipoprotein
CY774_RS11135	COG4181	ATPase activity
CY774_RS11145	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CY774_RS11150	COG0584	glycerophosphoryl diester phosphodiesterase
CY774_RS11155	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CY774_RS11165	COG0678	peroxiredoxin activity
CY774_RS11165	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CY774_RS11175	COG0789	Transcriptional regulator
CY774_RS11180	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CY774_RS11210	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CY774_RS11215	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CY774_RS11225	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CY774_RS11230	COG2252	PERMEase
CY774_RS11240	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CY774_RS11270	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CY774_RS11275	COG2358	TRAP transporter, solute receptor (TAXI family
CY774_RS11310	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CY774_RS11315	COG1366	Belongs to the anti-sigma-factor antagonist family
CY774_RS11320	COG2172	sigma factor antagonist activity
CY774_RS11325	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CY774_RS11335	COG2208	phosphoserine phosphatase activity
CY774_RS11335	COG2770	Histidine kinase
CY774_RS11360	COG1595	DNA-templated transcription, initiation
CY774_RS11375	COG4792	protein secretion
CY774_RS11380	COG4791	protein targeting
CY774_RS11385	COG4794	Type iii secretion
CY774_RS11390	COG4790	Type iii secretion
CY774_RS11425	COG4669	(LipO)protein
CY774_RS11490	COG4789	Type iii secretion
CY774_RS11520	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CY774_RS11525	COG0840	transmembrane signaling receptor activity
CY774_RS11530	COG2233	PERMEase
CY774_RS11555	COG1840	ABC-type Fe3 transport system, periplasmic component
CY774_RS11560	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CY774_RS11565	COG1178	ABC-type Fe3 transport system permease component
CY774_RS11570	COG3842	ATPase activity
CY774_RS11575	COG0583	DNA-binding transcription factor activity
CY774_RS11595	COG0501	Belongs to the peptidase M48B family
CY774_RS11605	COG0697	spore germination
CY774_RS11615	COG1846	Transcriptional regulator
CY774_RS11625	COG1566	PFAM secretion protein HlyD family protein
CY774_RS11630	COG2814	Major facilitator Superfamily
CY774_RS11635	COG0473	3-isopropylmalate dehydrogenase activity
CY774_RS11645	COG0747	negative chemotaxis
CY774_RS11655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CY774_RS11670	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CY774_RS11695	COG1012	belongs to the aldehyde dehydrogenase family
CY774_RS11705	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CY774_RS11710	COG1115	amino acid carrier protein
CY774_RS11715	COG0433	COG0433 Predicted ATPase
CY774_RS11720	COG0217	transcriptional regulatory protein
CY774_RS11725	COG0151	Belongs to the GarS family
CY774_RS11730	COG0408	coproporphyrinogen oxidase activity
CY774_RS11735	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CY774_RS11740	COG0799	negative regulation of ribosome biogenesis
CY774_RS11745	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CY774_RS11750	COG0424	maF-like protein
CY774_RS11755	COG3468	outer membrane autotransporter barrel domain protein
CY774_RS11795	COG1530	ribonuclease E activity
CY774_RS11800	COG0077	Prephenate dehydratase
CY774_RS11815	COG1132	(ABC) transporter
CY774_RS11820	COG0859	PFAM glycosyl transferase family 9
CY774_RS11855	COG2194	sulfuric ester hydrolase activity
CY774_RS11860	COG0438	transferase activity, transferring glycosyl groups
CY774_RS11865	COG0463	Glycosyl transferase, family 2
CY774_RS11870	COG0726	polysaccharide deacetylase
CY774_RS11875	COG0438	transferase activity, transferring glycosyl groups
CY774_RS11890	COG1643	Atp-dependent helicase
CY774_RS11895	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CY774_RS11895	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CY774_RS11900	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CY774_RS11910	COG0704	Plays a role in the regulation of phosphate uptake
CY774_RS11915	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CY774_RS11920	COG1960	acyl-CoA dehydrogenase activity
CY774_RS11945	COG1177	transmembrane transport
CY774_RS11950	COG1176	ABC-type spermidine putrescine transport system, permease component I
CY774_RS11955	COG3842	ATPase activity
CY774_RS11960	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CY774_RS11975	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CY774_RS11980	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CY774_RS11990	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CY774_RS11990	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CY774_RS12005	COG0372	Belongs to the citrate synthase family
CY774_RS12010	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CY774_RS12015	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CY774_RS12020	COG1053	succinate dehydrogenase
CY774_RS12025	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CY774_RS12030	COG2009	succinate dehydrogenase
CY774_RS12035	COG2188	Transcriptional regulator
CY774_RS12040	COG0039	L-malate dehydrogenase activity
CY774_RS12070	COG1981	membrane
CY774_RS12095	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CY774_RS12105	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CY774_RS12135	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CY774_RS12140	COG0148	phosphopyruvate hydratase activity
CY774_RS12150	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CY774_RS12155	COG0504	CTP synthase activity
CY774_RS12180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CY774_RS12190	COG0747	negative chemotaxis
CY774_RS12195	COG4172	Belongs to the ABC transporter superfamily
CY774_RS12200	COG1446	asparaginase
CY774_RS12230	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CY774_RS12245	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CY774_RS12250	COG0697	spore germination
CY774_RS12255	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CY774_RS12265	COG3193	protein, possibly involved in utilization of glycolate and propanediol
CY774_RS12275	COG0791	NLP P60 protein
CY774_RS12290	COG0583	DNA-binding transcription factor activity
CY774_RS12305	COG0583	DNA-binding transcription factor activity
CY774_RS12315	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CY774_RS12330	COG0670	Belongs to the BI1 family
CY774_RS12335	COG3181	Tripartite tricarboxylate transporter family receptor
CY774_RS12365	COG1381	Involved in DNA repair and RecF pathway recombination
CY774_RS12370	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CY774_RS12375	COG0571	ribonuclease III activity
CY774_RS12380	COG0681	Belongs to the peptidase S26 family
CY774_RS12385	COG0481	GTPase activity
CY774_RS12390	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CY774_RS12415	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CY774_RS12420	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CY774_RS12435	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CY774_RS12440	COG0416	fatty acid biosynthetic process
CY774_RS12445	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CY774_RS12450	COG1399	metal-binding, possibly nucleic acid-binding protein
CY774_RS12455	COG0424	maF-like protein
CY774_RS12465	COG3023	N-Acetylmuramoyl-L-alanine amidase
CY774_RS12485	COG3022	response to hydroperoxide
CY774_RS12495	COG1028	Short-chain dehydrogenase reductase Sdr
CY774_RS12510	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CY774_RS12540	COG2814	Major facilitator Superfamily
CY774_RS12560	COG3706	GGDEF domain
CY774_RS12585	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CY774_RS12590	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CY774_RS12595	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CY774_RS12600	COG1674	ftsk spoiiie
CY774_RS12605	COG0492	ferredoxin-NADP+ reductase activity
CY774_RS12610	COG1193	negative regulation of DNA recombination
CY774_RS12630	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CY774_RS12645	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CY774_RS12650	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CY774_RS12655	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CY774_RS12665	COG0745	RESPONSE REGULATOR receiver
CY774_RS12710	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CY774_RS12730	COG0612	Peptidase, M16
CY774_RS12740	COG0443	Heat shock 70 kDa protein
CY774_RS12750	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CY774_RS12760	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CY774_RS12765	COG1420	regulation of RNA biosynthetic process
CY774_RS12770	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CY774_RS12775	COG0497	DNA recombination
CY774_RS12780	COG0735	belongs to the Fur family
CY774_RS12785	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CY774_RS12790	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CY774_RS12795	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CY774_RS12830	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CY774_RS12830	COG0446	pyridine nucleotide-disulphide oxidoreductase
CY774_RS12835	COG4311	Sarcosine oxidase, delta subunit
CY774_RS12840	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CY774_RS12850	COG0583	DNA-binding transcription factor activity
CY774_RS12860	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CY774_RS12885	COG4964	Belongs to the GSP D family
CY774_RS12945	COG0181	hydroxymethylbilane synthase activity
CY774_RS12950	COG0861	Integral membrane protein TerC family
CY774_RS12955	COG0861	Integral membrane protein TerC family
CY774_RS12960	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CY774_RS12965	COG0045	succinate-CoA ligase (ADP-forming) activity
CY774_RS12975	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CY774_RS12985	COG2137	regulation of response to DNA damage stimulus
CY774_RS12990	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CY774_RS13010	COG1024	Enoyl-CoA hydratase
CY774_RS13010	COG1250	3-hydroxyacyl-CoA dehydrogenase
CY774_RS13015	COG3842	ATPase activity
CY774_RS13030	COG1028	Short-chain dehydrogenase reductase Sdr
CY774_RS13050	COG0583	DNA-binding transcription factor activity
CY774_RS13055	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CY774_RS13065	COG2974	May be involved in recombination
CY774_RS13070	COG0540	Belongs to the ATCase OTCase family
CY774_RS13135	COG0776	regulation of translation
CY774_RS13140	COG0072	phenylalanine-tRNA ligase activity
CY774_RS13140	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CY774_RS13145	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CY774_RS13150	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CY774_RS13155	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CY774_RS13165	COG0756	dUTP diphosphatase activity
CY774_RS13175	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CY774_RS13190	COG0500	methyltransferase
CY774_RS13205	COG0586	Pfam SNARE associated Golgi protein
CY774_RS13235	COG1609	Transcriptional regulator
CY774_RS13240	COG4172	Belongs to the ABC transporter superfamily
CY774_RS13245	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CY774_RS13250	COG0601	transmembrane transport
CY774_RS13255	COG0747	negative chemotaxis
CY774_RS13275	COG1280	lysine exporter protein (LysE YggA)
CY774_RS13290	COG2814	Major facilitator Superfamily
CY774_RS13320	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CY774_RS13340	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CY774_RS13375	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CY774_RS13380	COG1116	anion transmembrane transporter activity
CY774_RS13390	COG1228	amidohydrolase
CY774_RS13405	COG0477	Major facilitator Superfamily
CY774_RS13415	COG3550	peptidyl-serine autophosphorylation
CY774_RS13430	COG0519	Catalyzes the synthesis of GMP from XMP
CY774_RS13430	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CY774_RS13475	COG0420	3'-5' exonuclease activity
CY774_RS13480	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CY774_RS13510	COG0395	ABC-type sugar transport system, permease component
CY774_RS13520	COG3842	ATPase activity
CY774_RS13545	COG3181	Tripartite tricarboxylate transporter family receptor
CY774_RS13580	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CY774_RS13605	COG0602	queuosine metabolic process
CY774_RS13610	COG0720	synthase
CY774_RS13615	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CY774_RS13620	COG0235	Class ii aldolase
CY774_RS13650	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CY774_RS13650	COG3064	Membrane
CY774_RS13650	COG3210	domain, Protein
CY774_RS13655	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CY774_RS13655	COG0047	phosphoribosylformylglycinamidine synthase activity
CY774_RS13660	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CY774_RS13665	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CY774_RS13665	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CY774_RS13670	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CY774_RS13690	COG3539	Fimbrial protein
CY774_RS13700	COG2050	protein possibly involved in aromatic compounds catabolism
CY774_RS13705	COG1024	Enoyl-CoA hydratase
CY774_RS13710	COG1012	belongs to the aldehyde dehydrogenase family
CY774_RS13730	COG2151	metal-sulfur cluster biosynthetic enzyme
CY774_RS13735	COG3396	Phenylacetate-CoA oxygenase
CY774_RS13740	COG3460	Phenylacetate-CoA oxygenase
CY774_RS13745	COG3396	Phenylacetate-CoA oxygenase
CY774_RS13750	COG3327	negative regulation of DNA-templated transcription, initiation
CY774_RS13760	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CY774_RS13765	COG0501	Belongs to the peptidase M48B family
CY774_RS13770	COG1162	GTPase activity
CY774_RS13785	COG0601	transmembrane transport
CY774_RS13790	COG0747	negative chemotaxis
CY774_RS13835	COG0668	transmembrane transport
CY774_RS13840	COG0165	Argininosuccinate lyase
CY774_RS13860	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CY774_RS13865	COG0303	'Molybdopterin
CY774_RS13870	COG0521	Mo-molybdopterin cofactor biosynthetic process
CY774_RS13885	COG0315	cyclic pyranopterin monophosphate synthase activity
CY774_RS13895	COG0412	Dienelactone hydrolase
CY774_RS13905	COG0678	peroxiredoxin activity
CY774_RS13915	COG0697	spore germination
CY774_RS13920	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CY774_RS13945	COG0789	Transcriptional regulator
CY774_RS13965	COG1028	Short-chain dehydrogenase reductase Sdr
CY774_RS13975	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CY774_RS13980	COG1845	cytochrome c oxidase, subunit III
CY774_RS13985	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CY774_RS13995	COG0477	Major facilitator Superfamily
CY774_RS14030	COG1309	transcriptional regulator
CY774_RS14035	COG2271	Major facilitator Superfamily
CY774_RS14070	COG0506	proline dehydrogenase activity
CY774_RS14070	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CY774_RS14070	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CY774_RS14080	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CY774_RS14080	COG3008	intermembrane lipid transfer
CY774_RS14085	COG2995	paraquat-inducible protein a
CY774_RS14090	COG0542	response to heat
CY774_RS14095	COG4953	penicillin-binding protein 1C
CY774_RS14105	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CY774_RS14110	COG1278	Cold shock
CY774_RS14120	COG0183	Belongs to the thiolase family
CY774_RS14125	COG0038	chloride channel
CY774_RS14130	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CY774_RS14135	COG1570	exodeoxyribonuclease VII activity
CY774_RS14145	COG0811	peptide transport
CY774_RS14150	COG0848	biopolymer transport protein
CY774_RS14155	COG1663	tetraacyldisaccharide 4'-kinase activity
CY774_RS14160	COG2835	tetraacyldisaccharide 4'-kinase activity
CY774_RS14165	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CY774_RS14170	COG0563	adenylate kinase activity
CY774_RS14180	COG0728	peptidoglycan biosynthetic process
CY774_RS14190	COG0268	Binds directly to 16S ribosomal RNA
CY774_RS14225	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CY774_RS14250	COG0436	Aminotransferase
CY774_RS14255	COG3737	Protein of unknown function (DUF498/DUF598)
CY774_RS14260	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CY774_RS14265	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CY774_RS14270	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CY774_RS14280	COG0305	Participates in initiation and elongation during chromosome replication
CY774_RS14290	COG0359	binds to the 23S rRNA
CY774_RS14295	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CY774_RS14300	COG2965	DNA replication, synthesis of RNA primer
CY774_RS14305	COG0360	Binds together with S18 to 16S ribosomal RNA
CY774_RS14310	COG1469	GTP cyclohydrolase I activity
CY774_RS14315	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CY774_RS14320	COG0142	geranyltranstransferase activity
CY774_RS14325	COG1722	exodeoxyribonuclease VII activity
CY774_RS14335	COG3181	Tripartite tricarboxylate transporter family receptor
CY774_RS14355	COG2239	Acts as a magnesium transporter
CY774_RS14365	COG2855	membrane
CY774_RS14375	COG1473	amidohydrolase
CY774_RS14380	COG0318	PFAM AMP-dependent synthetase and ligase
CY774_RS14405	COG1501	Belongs to the glycosyl hydrolase 31 family
CY774_RS14410	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CY774_RS14415	COG2011	ABC-type metal ion transport system permease component
CY774_RS14435	COG1454	alcohol dehydrogenase
CY774_RS14465	COG2186	Transcriptional regulator
CY774_RS14470	COG3181	Tripartite tricarboxylate transporter family receptor
CY774_RS14490	COG1175	transmembrane transport
CY774_RS14495	COG0395	ABC-type sugar transport system, permease component
CY774_RS14500	COG3842	ATPase activity
CY774_RS14515	COG1653	transport
CY774_RS14535	COG2818	Glycosylase
CY774_RS14540	COG2982	Protein involved in outer membrane biogenesis
CY774_RS14550	COG1309	transcriptional regulator
CY774_RS14555	COG1028	Short-chain dehydrogenase reductase Sdr
CY774_RS14615	COG0583	DNA-binding transcription factor activity
CY774_RS14620	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CY774_RS14625	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CY774_RS14640	COG1028	Short-chain dehydrogenase reductase Sdr
CY774_RS14645	COG0477	Major facilitator Superfamily
CY774_RS14655	COG0583	DNA-binding transcription factor activity
CY774_RS14660	COG1448	Aminotransferase
CY774_RS14665	COG1418	mRNA catabolic process
CY774_RS14690	COG1063	alcohol dehydrogenase
CY774_RS14710	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CY774_RS14720	COG0318	PFAM AMP-dependent synthetase and ligase
CY774_RS14730	COG1522	sequence-specific DNA binding
CY774_RS14735	COG3181	Tripartite tricarboxylate transporter family receptor
CY774_RS14740	COG0307	riboflavin synthase, alpha
CY774_RS14745	COG0154	amidase activity
CY774_RS14765	COG2807	transmembrane transport
CY774_RS14770	COG0590	tRNA wobble adenosine to inosine editing
CY774_RS14780	COG0583	DNA-binding transcription factor activity
CY774_RS14815	COG0559	Belongs to the binding-protein-dependent transport system permease family
CY774_RS14820	COG0251	oxidation-reduction process
CY774_RS14825	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CY774_RS14835	COG1414	Transcriptional regulator
CY774_RS14840	COG1028	Short-chain dehydrogenase reductase Sdr
CY774_RS14855	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CY774_RS14870	COG1024	Enoyl-CoA hydratase
CY774_RS14875	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CY774_RS14880	COG0154	amidase activity
CY774_RS14920	COG3909	cytochrome
CY774_RS14925	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CY774_RS14930	COG0625	glutathione transferase activity
CY774_RS14935	COG0730	response to heat
CY774_RS14940	COG0482	sulfurtransferase activity
CY774_RS14945	COG0583	DNA-binding transcription factor activity
CY774_RS14985	COG2819	hydrolase of the alpha beta superfamily
CY774_RS14990	COG0247	lactate metabolic process
CY774_RS14995	COG0277	FAD linked oxidase domain protein
CY774_RS15000	COG0277	FAD linked oxidase domain protein
CY774_RS15005	COG0277	FAD linked oxidase domain protein
CY774_RS15010	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CY774_RS15010	COG3064	Membrane
CY774_RS15010	COG3210	domain, Protein
CY774_RS15010	COG3210	domain, Protein
CY774_RS15010	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CY774_RS15010	COG3064	Membrane
CY774_RS15015	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CY774_RS15020	COG0312	modulator of DNA gyrase
CY774_RS15055	COG1666	GTP binding
CY774_RS15100	COG3220	belongs to the UPF0276 family
CY774_RS15120	COG0640	Transcriptional regulator
CY774_RS15125	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CY774_RS15130	COG1845	cytochrome c oxidase, subunit III
CY774_RS15135	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CY774_RS15145	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CY774_RS15180	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CY774_RS15185	COG0583	DNA-binding transcription factor activity
CY774_RS15220	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CY774_RS15220	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CY774_RS15235	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CY774_RS15240	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CY774_RS15250	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CY774_RS15265	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CY774_RS15270	COG0316	Belongs to the HesB IscA family
CY774_RS15280	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CY774_RS15285	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CY774_RS15290	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CY774_RS15295	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CY774_RS15300	COG0312	modulator of DNA gyrase
CY774_RS15305	COG3028	Belongs to the UPF0307 family
CY774_RS15320	COG1116	anion transmembrane transporter activity
CY774_RS15325	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CY774_RS15330	COG1335	isochorismatase
CY774_RS15335	COG0346	lactoylglutathione lyase activity
CY774_RS15340	COG0513	Belongs to the DEAD box helicase family
CY774_RS15345	COG3069	C4-dicarboxylate transmembrane transporter activity
CY774_RS15350	COG1802	Transcriptional regulator
CY774_RS15365	COG0045	succinate-CoA ligase (ADP-forming) activity
CY774_RS15365	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CY774_RS15365	COG1042	CoA-binding domain protein
CY774_RS15370	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CY774_RS15385	COG1522	sequence-specific DNA binding
CY774_RS15420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CY774_RS15425	COG1696	Membrane protein involved in D-alanine export
CY774_RS15450	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CY774_RS15465	COG0439	Biotin carboxylase
CY774_RS15470	COG0511	ligase activity, forming carbon-carbon bonds
CY774_RS15475	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CY774_RS15480	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CY774_RS15485	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CY774_RS15490	COG3150	esterase
CY774_RS15495	COG0557	exoribonuclease II activity
CY774_RS15505	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CY774_RS15525	COG1522	sequence-specific DNA binding
CY774_RS15530	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CY774_RS15535	COG1028	Short-chain dehydrogenase reductase Sdr
CY774_RS15555	COG0653	protein targeting
CY774_RS15560	COG0739	heme binding
CY774_RS15570	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CY774_RS15575	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CY774_RS15585	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CY774_RS15590	COG1181	Belongs to the D-alanine--D-alanine ligase family
CY774_RS15595	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CY774_RS15600	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CY774_RS15610	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CY774_RS15615	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CY774_RS15620	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CY774_RS15630	COG3116	cell division
CY774_RS15635	COG0275	rRNA processing
CY774_RS15640	COG2001	Belongs to the MraZ family
CY774_RS15650	COG0488	(ABC) transporter
CY774_RS15655	COG0418	dihydroorotase activity
CY774_RS15660	COG1473	amidohydrolase
CY774_RS15710	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CY774_RS15715	COG4654	Cytochrome c, class I
CY774_RS15720	COG0129	dihydroxy-acid dehydratase activity
CY774_RS15725	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CY774_RS15780	COG2084	Dehydrogenase
CY774_RS15800	COG2096	Adenosyltransferase
CY774_RS15815	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CY774_RS15820	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CY774_RS15830	COG0523	cobalamin synthesis protein
CY774_RS15835	COG0735	belongs to the Fur family
CY774_RS15850	COG0803	Belongs to the bacterial solute-binding protein 9 family
CY774_RS15860	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CY774_RS15870	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CY774_RS15880	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CY774_RS15885	COG1560	Kdo2-lipid A biosynthetic process
CY774_RS15895	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CY774_RS15910	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CY774_RS15915	COG1950	PFAM Membrane protein of
CY774_RS15930	COG0583	DNA-binding transcription factor activity
CY774_RS15940	COG0477	Major facilitator Superfamily
CY774_RS15955	COG0617	tRNA 3'-terminal CCA addition
CY774_RS15965	COG0513	Belongs to the DEAD box helicase family
CY774_RS15970	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CY774_RS15980	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CY774_RS15985	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CY774_RS16060	COG0405	Gamma-glutamyltransferase
CY774_RS16070	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CY774_RS16100	COG1309	transcriptional regulator
CY774_RS16115	COG0745	RESPONSE REGULATOR receiver
CY774_RS16165	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CY774_RS16190	COG0582	viral genome integration into host DNA
CY774_RS16195	COG0012	GTP binding
CY774_RS16205	COG0193	aminoacyl-tRNA hydrolase activity
CY774_RS16210	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CY774_RS16215	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CY774_RS16225	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CY774_RS16230	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CY774_RS16240	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CY774_RS16265	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CY774_RS16275	COG1368	sulfuric ester hydrolase activity
CY774_RS16280	COG0642	Histidine kinase
CY774_RS16285	COG0745	RESPONSE REGULATOR receiver
CY774_RS16290	COG0277	FAD linked oxidase domain protein
CY774_RS16305	COG0166	Belongs to the GPI family
CY774_RS16310	COG0438	transferase activity, transferring glycosyl groups
CY774_RS16315	COG0438	transferase activity, transferring glycosyl groups
CY774_RS16330	COG0438	transferase activity, transferring glycosyl groups
CY774_RS16345	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CY774_RS16350	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CY774_RS16355	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
CY774_RS16365	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CY774_RS16375	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CY774_RS16380	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CY774_RS16390	COG0747	negative chemotaxis
CY774_RS16395	COG0601	transmembrane transport
CY774_RS16400	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CY774_RS16420	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CY774_RS16425	COG0830	nickel cation binding
CY774_RS16435	COG0804	urea catabolic process
CY774_RS16440	COG0832	Belongs to the urease beta subunit family
CY774_RS16450	COG0831	urea catabolic process
CY774_RS16455	COG0829	nickel cation binding
CY774_RS16485	COG2188	Transcriptional regulator
CY774_RS16510	COG2719	SpoVR family
CY774_RS16515	COG2718	Belongs to the UPF0229 family
CY774_RS16535	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CY774_RS16550	COG1960	acyl-CoA dehydrogenase activity
CY774_RS16600	COG2030	dehydratase
CY774_RS16650	COG0328	RNA-DNA hybrid ribonuclease activity
CY774_RS16655	COG2226	methyltransferase
CY774_RS16660	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CY774_RS16665	COG0741	lytic transglycosylase activity
CY774_RS16665	COG1388	LysM domain
CY774_RS16685	COG2979	Protein of unknown function (DUF533)
CY774_RS16720	COG1271	oxidase subunit
CY774_RS16725	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CY774_RS16730	COG0850	regulation of cytokinetic process
CY774_RS16735	COG2894	cell division
CY774_RS16740	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CY774_RS16775	COG0601	transmembrane transport
CY774_RS16785	COG1215	transferase activity, transferring glycosyl groups
CY774_RS16800	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CY774_RS16810	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CY774_RS16830	COG0318	PFAM AMP-dependent synthetase and ligase
CY774_RS16835	COG2188	Transcriptional regulator
CY774_RS16840	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CY774_RS16845	COG2814	Major facilitator Superfamily
CY774_RS16855	COG0259	pyridoxamine-phosphate oxidase activity
CY774_RS16860	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CY774_RS16875	COG0583	DNA-binding transcription factor activity
CY774_RS16900	COG0134	indole-3-glycerol-phosphate synthase activity
CY774_RS16905	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CY774_RS16910	COG0512	Glutamine amidotransferase of anthranilate synthase
CY774_RS16920	COG0546	phosphoglycolate phosphatase activity
CY774_RS16925	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CY774_RS16930	COG2967	ApaG domain
CY774_RS16935	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CY774_RS16940	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CY774_RS16945	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CY774_RS16950	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CY774_RS16960	COG0037	tRNA processing
CY774_RS16970	COG3634	alkyl hydroperoxide reductase activity
CY774_RS16975	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CY774_RS16980	COG1024	Enoyl-CoA hydratase
CY774_RS17005	COG0356	it plays a direct role in the translocation of protons across the membrane
CY774_RS17015	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CY774_RS17020	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CY774_RS17025	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CY774_RS17030	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CY774_RS17035	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CY774_RS17040	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CY774_RS17050	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CY774_RS17055	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CY774_RS17060	COG0210	DNA helicase
CY774_RS17070	COG2195	Cleaves the N-terminal amino acid of tripeptides
CY774_RS17080	COG4172	Belongs to the ABC transporter superfamily
CY774_RS17085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CY774_RS17090	COG0601	transmembrane transport
CY774_RS17110	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CY774_RS17115	COG1024	Enoyl-CoA hydratase
CY774_RS17120	COG1024	Enoyl-CoA hydratase
CY774_RS17175	COG2132	Multicopper oxidase
CY774_RS17185	COG1024	Enoyl-CoA hydratase
CY774_RS17185	COG1250	3-hydroxyacyl-CoA dehydrogenase
CY774_RS17195	COG1414	Transcriptional regulator
CY774_RS17205	COG0154	amidase activity
CY774_RS17235	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CY774_RS17240	COG3568	Endonuclease Exonuclease Phosphatase
CY774_RS17245	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CY774_RS17280	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CY774_RS17290	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CY774_RS17305	COG1137	ATPase activity
CY774_RS17320	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CY774_RS17325	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CY774_RS17325	COG2010	Cytochrome c
CY774_RS17335	COG1660	Displays ATPase and GTPase activities
CY774_RS17340	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CY774_RS17375	COG3181	Tripartite tricarboxylate transporter family receptor
CY774_RS17385	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CY774_RS17390	COG2890	protein-(glutamine-N5) methyltransferase activity
CY774_RS17395	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CY774_RS17400	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CY774_RS17450	COG1960	acyl-CoA dehydrogenase activity
CY774_RS17460	COG0183	Belongs to the thiolase family
CY774_RS17465	COG1522	sequence-specific DNA binding
CY774_RS17470	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CY774_RS17490	COG1024	Enoyl-CoA hydratase
CY774_RS17505	COG0604	alcohol dehydrogenase
CY774_RS17525	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CY774_RS17535	COG1960	acyl-CoA dehydrogenase activity
CY774_RS17540	COG1960	acyl-CoA dehydrogenase activity
CY774_RS17545	COG0277	FAD linked oxidase domain protein
CY774_RS17555	COG3181	Tripartite tricarboxylate transporter family receptor
CY774_RS17580	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CY774_RS17590	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CY774_RS17595	COG3181	Tripartite tricarboxylate transporter family receptor
CY774_RS17600	COG1960	acyl-CoA dehydrogenase activity
CY774_RS17620	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CY774_RS17625	COG1024	Enoyl-CoA hydratase
CY774_RS17630	COG1960	acyl-CoA dehydrogenase activity
CY774_RS17650	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CY774_RS17655	COG0022	dehydrogenase e1 component
CY774_RS17660	COG1024	Enoyl-CoA hydratase
CY774_RS17665	COG0508	dehydrogenase complex catalyzes the overall conversion of
CY774_RS17685	COG0683	leucine binding
CY774_RS17690	COG0559	Belongs to the binding-protein-dependent transport system permease family
CY774_RS17695	COG0411	ABC transporter
CY774_RS17705	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CY774_RS17720	COG3181	Tripartite tricarboxylate transporter family receptor
CY774_RS17750	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CY774_RS17755	COG0793	Belongs to the peptidase S41A family
CY774_RS17760	COG4942	peptidase
CY774_RS17765	COG0588	phosphoglycerate mutase activity
CY774_RS17770	COG1054	Belongs to the UPF0176 family
CY774_RS17775	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CY774_RS17780	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CY774_RS17785	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CY774_RS17790	COG3181	Tripartite tricarboxylate transporter family receptor
CY774_RS17805	COG2226	methyltransferase
CY774_RS17810	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CY774_RS17825	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CY774_RS17830	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CY774_RS17855	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CY774_RS17880	COG1335	isochorismatase
CY774_RS17885	COG2309	aminopeptidase activity
CY774_RS17895	COG3473	Maleate cis-trans isomerase
CY774_RS17905	COG2068	MobA-Related Protein
CY774_RS17930	COG2204	response regulator
CY774_RS17935	COG5000	phosphorelay sensor kinase activity
CY774_RS17945	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CY774_RS17945	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CY774_RS17955	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
CY774_RS17990	COG0583	DNA-binding transcription factor activity
CY774_RS18010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CY774_RS18015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CY774_RS18030	COG0758	DNA mediated transformation
CY774_RS18035	COG1522	sequence-specific DNA binding
CY774_RS18045	COG0242	peptide deformylase activity
CY774_RS18060	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CY774_RS18070	COG0546	phosphoglycolate phosphatase activity
CY774_RS18090	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CY774_RS18095	COG1942	4-Oxalocrotonate Tautomerase
CY774_RS18100	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CY774_RS18125	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CY774_RS18145	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CY774_RS18150	COG1024	Enoyl-CoA hydratase
CY774_RS18155	COG1414	Transcriptional regulator
CY774_RS18160	COG0318	PFAM AMP-dependent synthetase and ligase
CY774_RS18165	COG3181	Tripartite tricarboxylate transporter family receptor
CY774_RS18210	COG3422	double-strand break repair
CY774_RS18215	COG0330	HflC and HflK could
CY774_RS18225	COG0251	oxidation-reduction process
CY774_RS18275	COG3723	Recombinational DNA repair protein, rece pathway
CY774_RS18310	COG0582	viral genome integration into host DNA
CY774_RS18345	COG0706	membrane insertase activity
CY774_RS18350	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CY774_RS18355	COG0594	ribonuclease P activity
CY774_RS18360	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CY774_RS18365	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CY774_RS18380	COG1414	Transcriptional regulator
CY774_RS18385	COG0154	amidase activity
CY774_RS18400	COG1304	FMN binding
CY774_RS18450	COG0183	Belongs to the thiolase family
CY774_RS18455	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CY774_RS18470	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CY774_RS18475	COG3181	Tripartite tricarboxylate transporter family receptor
CY774_RS18485	COG2358	TRAP transporter, solute receptor (TAXI family
CY774_RS18495	COG1629	transport
CY774_RS18500	COG2922	Belongs to the Smg family
CY774_RS18525	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CY774_RS18530	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CY774_RS18535	COG1028	Short-chain dehydrogenase reductase Sdr
CY774_RS18540	COG1012	belongs to the aldehyde dehydrogenase family
CY774_RS18550	COG0028	Belongs to the TPP enzyme family
CY774_RS18555	COG1522	sequence-specific DNA binding
CY774_RS18560	COG3781	membrane
CY774_RS18570	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CY774_RS18590	COG4206	TonB-dependent receptor
CY774_RS18595	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CY774_RS18600	COG2022	thiamine diphosphate biosynthetic process
CY774_RS18605	COG0351	phosphomethylpyrimidine kinase
CY774_RS18610	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CY774_RS18625	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CY774_RS18635	COG0628	permease
CY774_RS18645	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CY774_RS18665	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CY774_RS18670	COG0049	tRNA binding
CY774_RS18675	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CY774_RS18680	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CY774_RS18685	COG0051	transcription antitermination factor activity, RNA binding
CY774_RS18690	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CY774_RS18695	COG0088	Forms part of the polypeptide exit tunnel
CY774_RS18700	COG0089	rRNA binding
CY774_RS18705	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CY774_RS18710	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CY774_RS18715	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CY774_RS18720	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CY774_RS18725	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CY774_RS18730	COG0255	Belongs to the universal ribosomal protein uL29 family
CY774_RS18735	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CY774_RS18755	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CY774_RS18760	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CY774_RS18765	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CY774_RS18770	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CY774_RS18775	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CY774_RS18780	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CY774_RS18785	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CY774_RS18790	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CY774_RS18795	COG1841	ribosomal large subunit assembly
CY774_RS18800	COG0200	Binds to the 23S rRNA
CY774_RS18805	COG0201	protein transport
CY774_RS18810	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CY774_RS18815	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CY774_RS18820	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CY774_RS18825	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CY774_RS18830	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CY774_RS18835	COG0202	RNA polymerase activity
CY774_RS18840	COG0203	ribosomal protein L17
CY774_RS18845	COG0537	adenosine 5'-monophosphoramidase activity
CY774_RS18850	COG1324	tolerance protein
CY774_RS18855	COG4232	protein-disulfide reductase activity
CY774_RS18870	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CY774_RS18880	COG1333	cytochrome c biogenesis protein
CY774_RS18885	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CY774_RS18900	COG1965	Belongs to the frataxin family
CY774_RS18910	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CY774_RS18915	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CY774_RS18920	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CY774_RS18935	COG2814	Major facilitator Superfamily
CY774_RS18940	COG0629	single-stranded DNA binding
CY774_RS18980	COG0402	S-adenosylhomocysteine deaminase activity
CY774_RS18990	COG0438	transferase activity, transferring glycosyl groups
CY774_RS19010	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CY774_RS19035	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CY774_RS19060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CY774_RS19065	COG1956	GAF domain-containing protein
CY774_RS19070	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CY774_RS19085	COG1652	LysM domain
CY774_RS19100	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CY774_RS19115	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CY774_RS19145	COG3181	Tripartite tricarboxylate transporter family receptor
CY774_RS19160	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CY774_RS19175	COG1024	Enoyl-CoA hydratase
CY774_RS19190	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CY774_RS19195	COG1309	transcriptional regulator
CY774_RS19200	COG2816	NAD+ diphosphatase activity
CY774_RS19205	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CY774_RS19290	COG2814	Major facilitator Superfamily
CY774_RS19295	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CY774_RS19315	COG1999	signal sequence binding
CY774_RS19320	COG0109	protoheme IX farnesyltransferase activity
CY774_RS19360	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CY774_RS19380	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CY774_RS19385	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CY774_RS19395	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CY774_RS19400	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CY774_RS19410	COG0067	glutamate synthase
CY774_RS19410	COG0069	glutamate synthase activity
CY774_RS19410	COG0070	glutamate synthase
CY774_RS19420	COG3047	cAMP biosynthetic process
CY774_RS19430	COG1127	ABC transporter
CY774_RS19435	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CY774_RS19440	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CY774_RS19445	COG2853	Lipoprotein
CY774_RS19460	COG0842	Transport permease protein
CY774_RS19470	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CY774_RS19475	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CY774_RS19480	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CY774_RS19485	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CY774_RS19490	COG0131	Imidazoleglycerol-phosphate dehydratase
CY774_RS19495	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CY774_RS19500	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CY774_RS19505	COG0107	imidazoleglycerol-phosphate synthase activity
CY774_RS19510	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CY774_RS19515	COG0140	phosphoribosyl-ATP diphosphatase activity
CY774_RS19520	COG0537	adenosine 5'-monophosphoramidase activity
CY774_RS19525	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CY774_RS19530	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CY774_RS19545	COG3181	Tripartite tricarboxylate transporter family receptor
CY774_RS19580	COG3702	type iv secretory pathway
CY774_RS19585	COG3451	type IV secretory pathway VirB4
CY774_RS19600	COG3736	Type IV secretory pathway, component VirB8
CY774_RS19605	COG3504	Conjugal transfer protein
CY774_RS19610	COG2948	multi-organism process
CY774_RS19615	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
CY774_RS19625	COG0697	spore germination
CY774_RS19645	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CY774_RS19650	COG0747	negative chemotaxis
CY774_RS19655	COG0601	transmembrane transport
CY774_RS19660	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CY774_RS19675	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CY774_RS19685	COG0494	nUDIX hydrolase
CY774_RS19730	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
CY774_RS19735	COG0237	dephospho-CoA kinase activity
CY774_RS19740	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CY774_RS19755	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CY774_RS19760	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CY774_RS19770	COG0477	Major facilitator Superfamily
CY774_RS19775	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CY774_RS19790	COG1126	abc transporter atp-binding protein
CY774_RS19795	COG0765	amino acid transport
CY774_RS19800	COG4597	amino acid ABC transporter
CY774_RS19805	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CY774_RS19810	COG2884	Cell division ATP-binding protein ftsE
CY774_RS19815	COG2177	Part of the ABC transporter FtsEX involved in
CY774_RS19820	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CY774_RS19830	COG1194	a g-specific adenine glycosylase
CY774_RS19840	COG2226	methyltransferase
CY774_RS19850	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CY774_RS19855	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CY774_RS19870	COG1024	Enoyl-CoA hydratase
CY774_RS19890	COG1024	Enoyl-CoA hydratase
CY774_RS19895	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CY774_RS19910	COG0753	catalase activity
CY774_RS19915	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CY774_RS19920	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CY774_RS19930	COG2175	clavaminate synthase activity
CY774_RS19935	COG1473	amidohydrolase
CY774_RS19940	COG4608	Belongs to the ABC transporter superfamily
CY774_RS19945	COG0444	Belongs to the ABC transporter superfamily
CY774_RS19960	COG0747	negative chemotaxis
CY774_RS19965	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CY774_RS20000	COG0436	Aminotransferase
CY774_RS20005	COG1278	Cold shock