locus-tag	class	description
CX039_RS00005	COG0445	tRNA wobble uridine modification
CX039_RS00010	COG0357	Ribosomal RNA small subunit methyltransferase G
CX039_RS00015	COG1192	Involved in chromosome partitioning
CX039_RS00025	COG1475	DNA binding
CX039_RS00050	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CX039_RS00060	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CX039_RS00070	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CX039_RS00075	COG0081	regulation of translation
CX039_RS00080	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CX039_RS00085	COG0222	ribosome binding
CX039_RS00090	COG0085	RNA polymerase activity
CX039_RS00095	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CX039_RS00135	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX039_RS00160	COG1024	Enoyl-CoA hydratase
CX039_RS00180	COG0752	glycyl-tRNA synthetase alpha subunit
CX039_RS00185	COG0751	glycine-tRNA ligase activity
CX039_RS00190	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CX039_RS00195	COG0204	Acyl-transferase
CX039_RS00210	COG0242	peptide deformylase activity
CX039_RS00250	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CX039_RS00255	COG2813	Specifically methylates the guanine in position
CX039_RS00255	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CX039_RS00270	COG2223	nitrite transmembrane transporter activity
CX039_RS00280	COG1794	racemase activity, acting on amino acids and derivatives
CX039_RS00285	COG1126	abc transporter atp-binding protein
CX039_RS00290	COG0765	amino acid transport
CX039_RS00295	COG0765	amino acid transport
CX039_RS00300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CX039_RS00365	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CX039_RS00395	COG0326	Molecular chaperone. Has ATPase activity
CX039_RS00400	COG0625	glutathione transferase activity
CX039_RS00415	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CX039_RS00420	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CX039_RS00450	COG0438	transferase activity, transferring glycosyl groups
CX039_RS00455	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CX039_RS00460	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CX039_RS00490	COG0859	PFAM glycosyl transferase family 9
CX039_RS00505	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CX039_RS00515	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CX039_RS00520	COG1127	ABC transporter
CX039_RS00540	COG1686	Belongs to the peptidase S11 family
CX039_RS00550	COG2921	Belongs to the UPF0250 family
CX039_RS00555	COG0321	lipoyl(octanoyl) transferase activity
CX039_RS00560	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CX039_RS00595	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CX039_RS00605	COG0018	arginyl-trna synthetase
CX039_RS00625	COG0395	ABC-type sugar transport system, permease component
CX039_RS00630	COG1175	transmembrane transport
CX039_RS00635	COG1653	transport
CX039_RS00640	COG3842	ATPase activity
CX039_RS00645	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CX039_RS00720	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CX039_RS00725	COG2816	NAD+ diphosphatase activity
CX039_RS00730	COG1309	transcriptional regulator
CX039_RS00735	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX039_RS00750	COG1024	Enoyl-CoA hydratase
CX039_RS00765	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CX039_RS00780	COG3181	Tripartite tricarboxylate transporter family receptor
CX039_RS00810	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CX039_RS00825	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CX039_RS00840	COG1652	LysM domain
CX039_RS00855	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CX039_RS00860	COG1956	GAF domain-containing protein
CX039_RS00865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CX039_RS00890	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CX039_RS00915	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CX039_RS00935	COG0438	transferase activity, transferring glycosyl groups
CX039_RS00945	COG0402	S-adenosylhomocysteine deaminase activity
CX039_RS00985	COG0629	single-stranded DNA binding
CX039_RS00990	COG2814	Major facilitator Superfamily
CX039_RS01005	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CX039_RS01010	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CX039_RS01015	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CX039_RS01025	COG1965	Belongs to the frataxin family
CX039_RS01040	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CX039_RS01045	COG1333	cytochrome c biogenesis protein
CX039_RS01055	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CX039_RS01070	COG4232	protein-disulfide reductase activity
CX039_RS01075	COG1324	tolerance protein
CX039_RS01080	COG0537	adenosine 5'-monophosphoramidase activity
CX039_RS01085	COG0203	ribosomal protein L17
CX039_RS01090	COG0202	RNA polymerase activity
CX039_RS01095	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CX039_RS01100	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CX039_RS01105	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CX039_RS01110	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CX039_RS01115	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CX039_RS01120	COG0201	protein transport
CX039_RS01125	COG0200	Binds to the 23S rRNA
CX039_RS01130	COG1841	ribosomal large subunit assembly
CX039_RS01135	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CX039_RS01140	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CX039_RS01145	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CX039_RS01150	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CX039_RS01155	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CX039_RS01160	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CX039_RS01165	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CX039_RS01170	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CX039_RS01190	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CX039_RS01195	COG0255	Belongs to the universal ribosomal protein uL29 family
CX039_RS01200	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CX039_RS01205	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CX039_RS01210	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CX039_RS01215	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CX039_RS01220	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CX039_RS01225	COG0089	rRNA binding
CX039_RS01230	COG0088	Forms part of the polypeptide exit tunnel
CX039_RS01235	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CX039_RS01240	COG0051	transcription antitermination factor activity, RNA binding
CX039_RS01245	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CX039_RS01250	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CX039_RS01255	COG0049	tRNA binding
CX039_RS01260	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CX039_RS01275	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CX039_RS01285	COG0628	permease
CX039_RS01295	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CX039_RS01305	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CX039_RS01310	COG0351	phosphomethylpyrimidine kinase
CX039_RS01315	COG2022	thiamine diphosphate biosynthetic process
CX039_RS01320	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CX039_RS01325	COG4206	TonB-dependent receptor
CX039_RS01345	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CX039_RS01355	COG3781	membrane
CX039_RS01360	COG1522	sequence-specific DNA binding
CX039_RS01365	COG0028	Belongs to the TPP enzyme family
CX039_RS01375	COG1012	belongs to the aldehyde dehydrogenase family
CX039_RS01380	COG1028	Short-chain dehydrogenase reductase Sdr
CX039_RS01385	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CX039_RS01390	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CX039_RS01415	COG2922	Belongs to the Smg family
CX039_RS01420	COG1629	transport
CX039_RS01430	COG2358	TRAP transporter, solute receptor (TAXI family
CX039_RS01440	COG3181	Tripartite tricarboxylate transporter family receptor
CX039_RS01445	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CX039_RS01460	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CX039_RS01465	COG0183	Belongs to the thiolase family
CX039_RS01515	COG1304	FMN binding
CX039_RS01530	COG0154	amidase activity
CX039_RS01535	COG1414	Transcriptional regulator
CX039_RS01550	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CX039_RS01555	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CX039_RS01560	COG0594	ribonuclease P activity
CX039_RS01565	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CX039_RS01570	COG0706	membrane insertase activity
CX039_RS01605	COG0582	viral genome integration into host DNA
CX039_RS01640	COG3723	Recombinational DNA repair protein, rece pathway
CX039_RS01690	COG0251	oxidation-reduction process
CX039_RS01700	COG0330	HflC and HflK could
CX039_RS01705	COG3422	double-strand break repair
CX039_RS01750	COG3181	Tripartite tricarboxylate transporter family receptor
CX039_RS01755	COG0318	PFAM AMP-dependent synthetase and ligase
CX039_RS01760	COG1414	Transcriptional regulator
CX039_RS01765	COG1024	Enoyl-CoA hydratase
CX039_RS01770	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CX039_RS01790	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CX039_RS01815	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CX039_RS01820	COG1942	4-Oxalocrotonate Tautomerase
CX039_RS01825	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CX039_RS01845	COG0546	phosphoglycolate phosphatase activity
CX039_RS01855	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CX039_RS01870	COG0242	peptide deformylase activity
CX039_RS01880	COG1522	sequence-specific DNA binding
CX039_RS01885	COG0758	DNA mediated transformation
CX039_RS01900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CX039_RS01905	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CX039_RS01925	COG0583	DNA-binding transcription factor activity
CX039_RS01955	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
CX039_RS01965	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CX039_RS01965	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CX039_RS01975	COG5000	phosphorelay sensor kinase activity
CX039_RS01980	COG2204	response regulator
CX039_RS02005	COG2068	MobA-Related Protein
CX039_RS02015	COG3473	Maleate cis-trans isomerase
CX039_RS02025	COG2309	aminopeptidase activity
CX039_RS02030	COG1335	isochorismatase
CX039_RS02055	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CX039_RS02080	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CX039_RS02085	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CX039_RS02100	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CX039_RS02105	COG2226	methyltransferase
CX039_RS02120	COG3181	Tripartite tricarboxylate transporter family receptor
CX039_RS02125	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CX039_RS02130	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CX039_RS02135	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CX039_RS02140	COG1054	Belongs to the UPF0176 family
CX039_RS02145	COG0588	phosphoglycerate mutase activity
CX039_RS02150	COG4942	peptidase
CX039_RS02155	COG0793	Belongs to the peptidase S41A family
CX039_RS02160	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CX039_RS02185	COG3181	Tripartite tricarboxylate transporter family receptor
CX039_RS02200	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CX039_RS02210	COG0411	ABC transporter
CX039_RS02215	COG0559	Belongs to the binding-protein-dependent transport system permease family
CX039_RS02220	COG0683	leucine binding
CX039_RS02240	COG0508	dehydrogenase complex catalyzes the overall conversion of
CX039_RS02245	COG1024	Enoyl-CoA hydratase
CX039_RS02250	COG0022	dehydrogenase e1 component
CX039_RS02255	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CX039_RS02275	COG1960	acyl-CoA dehydrogenase activity
CX039_RS02280	COG1024	Enoyl-CoA hydratase
CX039_RS02285	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CX039_RS02305	COG1960	acyl-CoA dehydrogenase activity
CX039_RS02310	COG3181	Tripartite tricarboxylate transporter family receptor
CX039_RS02315	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX039_RS02325	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CX039_RS02350	COG3181	Tripartite tricarboxylate transporter family receptor
CX039_RS02360	COG0277	FAD linked oxidase domain protein
CX039_RS02365	COG1960	acyl-CoA dehydrogenase activity
CX039_RS02370	COG1960	acyl-CoA dehydrogenase activity
CX039_RS02380	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CX039_RS02400	COG0604	alcohol dehydrogenase
CX039_RS02415	COG1024	Enoyl-CoA hydratase
CX039_RS02435	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CX039_RS02440	COG1522	sequence-specific DNA binding
CX039_RS02445	COG0183	Belongs to the thiolase family
CX039_RS02455	COG1960	acyl-CoA dehydrogenase activity
CX039_RS02500	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CX039_RS02505	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CX039_RS02510	COG2890	protein-(glutamine-N5) methyltransferase activity
CX039_RS02515	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CX039_RS02525	COG3181	Tripartite tricarboxylate transporter family receptor
CX039_RS02560	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CX039_RS02565	COG1660	Displays ATPase and GTPase activities
CX039_RS02575	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CX039_RS02575	COG2010	Cytochrome c
CX039_RS02580	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CX039_RS02595	COG1137	ATPase activity
CX039_RS02610	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CX039_RS02620	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CX039_RS02655	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CX039_RS02660	COG3568	Endonuclease Exonuclease Phosphatase
CX039_RS02665	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CX039_RS02695	COG0154	amidase activity
CX039_RS02705	COG1414	Transcriptional regulator
CX039_RS02715	COG1250	3-hydroxyacyl-CoA dehydrogenase
CX039_RS02715	COG1024	Enoyl-CoA hydratase
CX039_RS02725	COG2132	Multicopper oxidase
CX039_RS02780	COG1024	Enoyl-CoA hydratase
CX039_RS02785	COG1024	Enoyl-CoA hydratase
CX039_RS02790	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CX039_RS02810	COG0601	transmembrane transport
CX039_RS02815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CX039_RS02820	COG4172	Belongs to the ABC transporter superfamily
CX039_RS02830	COG2195	Cleaves the N-terminal amino acid of tripeptides
CX039_RS02840	COG0210	DNA helicase
CX039_RS02845	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CX039_RS02850	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CX039_RS02860	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CX039_RS02865	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CX039_RS02870	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CX039_RS02875	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CX039_RS02880	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CX039_RS02885	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CX039_RS02895	COG0356	it plays a direct role in the translocation of protons across the membrane
CX039_RS02920	COG1024	Enoyl-CoA hydratase
CX039_RS02925	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CX039_RS02930	COG3634	alkyl hydroperoxide reductase activity
CX039_RS02940	COG0037	tRNA processing
CX039_RS02950	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CX039_RS02955	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CX039_RS02960	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CX039_RS02965	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CX039_RS02970	COG2967	ApaG domain
CX039_RS02975	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CX039_RS02980	COG0546	phosphoglycolate phosphatase activity
CX039_RS02990	COG0512	Glutamine amidotransferase of anthranilate synthase
CX039_RS02995	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CX039_RS03000	COG0134	indole-3-glycerol-phosphate synthase activity
CX039_RS03025	COG0583	DNA-binding transcription factor activity
CX039_RS03040	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CX039_RS03045	COG0259	pyridoxamine-phosphate oxidase activity
CX039_RS03055	COG2814	Major facilitator Superfamily
CX039_RS03060	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CX039_RS03065	COG2188	Transcriptional regulator
CX039_RS03070	COG0318	PFAM AMP-dependent synthetase and ligase
CX039_RS03090	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CX039_RS03100	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CX039_RS03115	COG1215	transferase activity, transferring glycosyl groups
CX039_RS03125	COG0601	transmembrane transport
CX039_RS03160	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CX039_RS03165	COG2894	cell division
CX039_RS03170	COG0850	regulation of cytokinetic process
CX039_RS03175	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CX039_RS03180	COG1271	oxidase subunit
CX039_RS03215	COG2979	Protein of unknown function (DUF533)
CX039_RS03235	COG0741	lytic transglycosylase activity
CX039_RS03235	COG1388	LysM domain
CX039_RS03240	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CX039_RS03245	COG2226	methyltransferase
CX039_RS03250	COG0328	RNA-DNA hybrid ribonuclease activity
CX039_RS03300	COG2030	dehydratase
CX039_RS03350	COG1960	acyl-CoA dehydrogenase activity
CX039_RS03365	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX039_RS03385	COG2718	Belongs to the UPF0229 family
CX039_RS03390	COG2719	SpoVR family
CX039_RS03415	COG2188	Transcriptional regulator
CX039_RS03445	COG0829	nickel cation binding
CX039_RS03450	COG0831	urea catabolic process
CX039_RS03460	COG0832	Belongs to the urease beta subunit family
CX039_RS03465	COG0804	urea catabolic process
CX039_RS03475	COG0830	nickel cation binding
CX039_RS03480	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CX039_RS03500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CX039_RS03505	COG0601	transmembrane transport
CX039_RS03510	COG0747	negative chemotaxis
CX039_RS03520	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CX039_RS03525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CX039_RS03535	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CX039_RS03545	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
CX039_RS03550	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CX039_RS03555	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CX039_RS03570	COG0438	transferase activity, transferring glycosyl groups
CX039_RS03585	COG0438	transferase activity, transferring glycosyl groups
CX039_RS03590	COG0438	transferase activity, transferring glycosyl groups
CX039_RS03595	COG0166	Belongs to the GPI family
CX039_RS03610	COG0277	FAD linked oxidase domain protein
CX039_RS03615	COG0745	RESPONSE REGULATOR receiver
CX039_RS03620	COG0642	Histidine kinase
CX039_RS03625	COG1368	sulfuric ester hydrolase activity
CX039_RS03635	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CX039_RS03660	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CX039_RS03670	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CX039_RS03675	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CX039_RS03685	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CX039_RS03690	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CX039_RS03695	COG0193	aminoacyl-tRNA hydrolase activity
CX039_RS03705	COG0012	GTP binding
CX039_RS03710	COG0582	viral genome integration into host DNA
CX039_RS03735	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CX039_RS03800	COG0745	RESPONSE REGULATOR receiver
CX039_RS03815	COG1309	transcriptional regulator
CX039_RS03845	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CX039_RS03855	COG0405	Gamma-glutamyltransferase
CX039_RS03930	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CX039_RS03935	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CX039_RS03945	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CX039_RS03950	COG0513	Belongs to the DEAD box helicase family
CX039_RS03960	COG0617	tRNA 3'-terminal CCA addition
CX039_RS03975	COG0477	Major facilitator Superfamily
CX039_RS03985	COG0583	DNA-binding transcription factor activity
CX039_RS04000	COG1950	PFAM Membrane protein of
CX039_RS04005	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CX039_RS04020	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CX039_RS04030	COG1560	Kdo2-lipid A biosynthetic process
CX039_RS04035	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CX039_RS04045	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CX039_RS04055	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CX039_RS04065	COG0803	Belongs to the bacterial solute-binding protein 9 family
CX039_RS04080	COG0735	belongs to the Fur family
CX039_RS04085	COG0523	cobalamin synthesis protein
CX039_RS04095	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CX039_RS04100	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CX039_RS04115	COG2096	Adenosyltransferase
CX039_RS04135	COG2084	Dehydrogenase
CX039_RS04190	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CX039_RS04195	COG0129	dihydroxy-acid dehydratase activity
CX039_RS04200	COG4654	Cytochrome c, class I
CX039_RS04205	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CX039_RS04255	COG1473	amidohydrolase
CX039_RS04260	COG0418	dihydroorotase activity
CX039_RS04265	COG0488	(ABC) transporter
CX039_RS04275	COG2001	Belongs to the MraZ family
CX039_RS04280	COG0275	rRNA processing
CX039_RS04285	COG3116	cell division
CX039_RS04295	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CX039_RS04300	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CX039_RS04305	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CX039_RS04315	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CX039_RS04320	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CX039_RS04325	COG1181	Belongs to the D-alanine--D-alanine ligase family
CX039_RS04330	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CX039_RS04340	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CX039_RS04345	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CX039_RS04355	COG0739	heme binding
CX039_RS04360	COG0653	protein targeting
CX039_RS04380	COG1028	Short-chain dehydrogenase reductase Sdr
CX039_RS04385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CX039_RS04390	COG1522	sequence-specific DNA binding
CX039_RS04410	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CX039_RS04420	COG0557	exoribonuclease II activity
CX039_RS04425	COG3150	esterase
CX039_RS04430	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CX039_RS04435	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CX039_RS04440	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CX039_RS04445	COG0511	ligase activity, forming carbon-carbon bonds
CX039_RS04450	COG0439	Biotin carboxylase
CX039_RS04465	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CX039_RS04490	COG1696	Membrane protein involved in D-alanine export
CX039_RS04495	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CX039_RS04530	COG1522	sequence-specific DNA binding
CX039_RS04545	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CX039_RS04550	COG1042	CoA-binding domain protein
CX039_RS04550	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CX039_RS04550	COG0045	succinate-CoA ligase (ADP-forming) activity
CX039_RS04565	COG1802	Transcriptional regulator
CX039_RS04570	COG3069	C4-dicarboxylate transmembrane transporter activity
CX039_RS04575	COG0513	Belongs to the DEAD box helicase family
CX039_RS04580	COG0346	lactoylglutathione lyase activity
CX039_RS04585	COG1335	isochorismatase
CX039_RS04590	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CX039_RS04595	COG1116	anion transmembrane transporter activity
CX039_RS04610	COG3028	Belongs to the UPF0307 family
CX039_RS04615	COG0312	modulator of DNA gyrase
CX039_RS04620	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CX039_RS04625	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CX039_RS04630	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CX039_RS04635	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CX039_RS04645	COG0316	Belongs to the HesB IscA family
CX039_RS04650	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CX039_RS04665	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CX039_RS04675	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CX039_RS04680	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CX039_RS04695	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CX039_RS04695	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CX039_RS04730	COG0583	DNA-binding transcription factor activity
CX039_RS04735	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX039_RS04770	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CX039_RS04780	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CX039_RS04785	COG1845	cytochrome c oxidase, subunit III
CX039_RS04790	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CX039_RS04795	COG0640	Transcriptional regulator
CX039_RS04815	COG3220	belongs to the UPF0276 family
CX039_RS04860	COG1666	GTP binding
CX039_RS04895	COG0312	modulator of DNA gyrase
CX039_RS04900	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CX039_RS04905	COG3210	domain, Protein
CX039_RS04905	COG3064	Membrane
CX039_RS04905	COG3210	domain, Protein
CX039_RS04905	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CX039_RS04905	COG3064	Membrane
CX039_RS04905	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CX039_RS04910	COG0277	FAD linked oxidase domain protein
CX039_RS04915	COG0277	FAD linked oxidase domain protein
CX039_RS04920	COG0277	FAD linked oxidase domain protein
CX039_RS04925	COG0247	lactate metabolic process
CX039_RS04930	COG2819	hydrolase of the alpha beta superfamily
CX039_RS04970	COG0583	DNA-binding transcription factor activity
CX039_RS04975	COG0482	sulfurtransferase activity
CX039_RS04980	COG0730	response to heat
CX039_RS04985	COG0625	glutathione transferase activity
CX039_RS04990	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CX039_RS04995	COG3909	cytochrome
CX039_RS05035	COG0154	amidase activity
CX039_RS05040	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX039_RS05045	COG1024	Enoyl-CoA hydratase
CX039_RS05060	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CX039_RS05075	COG1028	Short-chain dehydrogenase reductase Sdr
CX039_RS05080	COG1414	Transcriptional regulator
CX039_RS05090	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CX039_RS05095	COG0251	oxidation-reduction process
CX039_RS05100	COG0559	Belongs to the binding-protein-dependent transport system permease family
CX039_RS05135	COG0583	DNA-binding transcription factor activity
CX039_RS05145	COG0590	tRNA wobble adenosine to inosine editing
CX039_RS05150	COG2807	transmembrane transport
CX039_RS05170	COG0154	amidase activity
CX039_RS05175	COG0307	riboflavin synthase, alpha
CX039_RS05180	COG3181	Tripartite tricarboxylate transporter family receptor
CX039_RS05185	COG1522	sequence-specific DNA binding
CX039_RS05195	COG0318	PFAM AMP-dependent synthetase and ligase
CX039_RS05205	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CX039_RS05225	COG1063	alcohol dehydrogenase
CX039_RS05250	COG1418	mRNA catabolic process
CX039_RS05255	COG1448	Aminotransferase
CX039_RS05260	COG0583	DNA-binding transcription factor activity
CX039_RS05270	COG0477	Major facilitator Superfamily
CX039_RS05275	COG1028	Short-chain dehydrogenase reductase Sdr
CX039_RS05290	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CX039_RS05295	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CX039_RS05300	COG0583	DNA-binding transcription factor activity
CX039_RS05360	COG1028	Short-chain dehydrogenase reductase Sdr
CX039_RS05365	COG1309	transcriptional regulator
CX039_RS05375	COG2982	Protein involved in outer membrane biogenesis
CX039_RS05380	COG2818	Glycosylase
CX039_RS05400	COG1653	transport
CX039_RS05415	COG3842	ATPase activity
CX039_RS05420	COG0395	ABC-type sugar transport system, permease component
CX039_RS05425	COG1175	transmembrane transport
CX039_RS05440	COG3181	Tripartite tricarboxylate transporter family receptor
CX039_RS05445	COG2186	Transcriptional regulator
CX039_RS05475	COG1454	alcohol dehydrogenase
CX039_RS05495	COG2011	ABC-type metal ion transport system permease component
CX039_RS05500	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CX039_RS05505	COG1501	Belongs to the glycosyl hydrolase 31 family
CX039_RS05530	COG0318	PFAM AMP-dependent synthetase and ligase
CX039_RS05535	COG1473	amidohydrolase
CX039_RS05545	COG2855	membrane
CX039_RS05555	COG2239	Acts as a magnesium transporter
CX039_RS05575	COG3181	Tripartite tricarboxylate transporter family receptor
CX039_RS05585	COG1722	exodeoxyribonuclease VII activity
CX039_RS05590	COG0142	geranyltranstransferase activity
CX039_RS05595	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CX039_RS05600	COG1469	GTP cyclohydrolase I activity
CX039_RS05605	COG0360	Binds together with S18 to 16S ribosomal RNA
CX039_RS05610	COG2965	DNA replication, synthesis of RNA primer
CX039_RS05615	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CX039_RS05620	COG0359	binds to the 23S rRNA
CX039_RS05630	COG0305	Participates in initiation and elongation during chromosome replication
CX039_RS05640	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CX039_RS05645	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CX039_RS05650	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CX039_RS05655	COG3737	Protein of unknown function (DUF498/DUF598)
CX039_RS05660	COG0436	Aminotransferase
CX039_RS05685	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CX039_RS05720	COG0268	Binds directly to 16S ribosomal RNA
CX039_RS05730	COG0728	peptidoglycan biosynthetic process
CX039_RS05740	COG0563	adenylate kinase activity
CX039_RS05745	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CX039_RS05750	COG2835	tetraacyldisaccharide 4'-kinase activity
CX039_RS05755	COG1663	tetraacyldisaccharide 4'-kinase activity
CX039_RS05760	COG0848	biopolymer transport protein
CX039_RS05765	COG0811	peptide transport
CX039_RS05775	COG1570	exodeoxyribonuclease VII activity
CX039_RS05780	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CX039_RS05785	COG0038	chloride channel
CX039_RS05790	COG0183	Belongs to the thiolase family
CX039_RS05800	COG1278	Cold shock
CX039_RS05805	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CX039_RS05815	COG4953	penicillin-binding protein 1C
CX039_RS05820	COG0542	response to heat
CX039_RS05825	COG2995	paraquat-inducible protein a
CX039_RS05830	COG3008	intermembrane lipid transfer
CX039_RS05830	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CX039_RS05840	COG0506	proline dehydrogenase activity
CX039_RS05840	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CX039_RS05840	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CX039_RS05875	COG2271	Major facilitator Superfamily
CX039_RS05880	COG1309	transcriptional regulator
CX039_RS05915	COG0477	Major facilitator Superfamily
CX039_RS05925	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CX039_RS05930	COG1845	cytochrome c oxidase, subunit III
CX039_RS05935	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CX039_RS05945	COG1028	Short-chain dehydrogenase reductase Sdr
CX039_RS05965	COG0789	Transcriptional regulator
CX039_RS05990	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CX039_RS05995	COG0697	spore germination
CX039_RS06005	COG0678	peroxiredoxin activity
CX039_RS06015	COG0412	Dienelactone hydrolase
CX039_RS06025	COG0315	cyclic pyranopterin monophosphate synthase activity
CX039_RS06040	COG0521	Mo-molybdopterin cofactor biosynthetic process
CX039_RS06045	COG0303	'Molybdopterin
CX039_RS06050	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CX039_RS06070	COG0165	Argininosuccinate lyase
CX039_RS06075	COG0668	transmembrane transport
CX039_RS06120	COG0747	negative chemotaxis
CX039_RS06125	COG0601	transmembrane transport
CX039_RS06140	COG1162	GTPase activity
CX039_RS06145	COG0501	Belongs to the peptidase M48B family
CX039_RS06150	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CX039_RS06160	COG3327	negative regulation of DNA-templated transcription, initiation
CX039_RS06165	COG3396	Phenylacetate-CoA oxygenase
CX039_RS06170	COG3460	Phenylacetate-CoA oxygenase
CX039_RS06175	COG3396	Phenylacetate-CoA oxygenase
CX039_RS06180	COG2151	metal-sulfur cluster biosynthetic enzyme
CX039_RS06200	COG1012	belongs to the aldehyde dehydrogenase family
CX039_RS06205	COG1024	Enoyl-CoA hydratase
CX039_RS06210	COG2050	protein possibly involved in aromatic compounds catabolism
CX039_RS06220	COG3539	Fimbrial protein
CX039_RS06240	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CX039_RS06245	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CX039_RS06245	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CX039_RS06250	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CX039_RS06255	COG0047	phosphoribosylformylglycinamidine synthase activity
CX039_RS06255	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CX039_RS06260	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CX039_RS06260	COG3210	domain, Protein
CX039_RS06260	COG3064	Membrane
CX039_RS06290	COG0235	Class ii aldolase
CX039_RS06295	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CX039_RS06300	COG0720	synthase
CX039_RS06305	COG0602	queuosine metabolic process
CX039_RS06330	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CX039_RS06365	COG3181	Tripartite tricarboxylate transporter family receptor
CX039_RS06390	COG3842	ATPase activity
CX039_RS06400	COG0395	ABC-type sugar transport system, permease component
CX039_RS06430	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CX039_RS06435	COG0420	3'-5' exonuclease activity
CX039_RS06480	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CX039_RS06480	COG0519	Catalyzes the synthesis of GMP from XMP
CX039_RS06495	COG3550	peptidyl-serine autophosphorylation
CX039_RS06505	COG0477	Major facilitator Superfamily
CX039_RS06520	COG1228	amidohydrolase
CX039_RS06530	COG1116	anion transmembrane transporter activity
CX039_RS06535	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CX039_RS06570	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CX039_RS06590	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CX039_RS06620	COG2814	Major facilitator Superfamily
CX039_RS06635	COG1280	lysine exporter protein (LysE YggA)
CX039_RS06650	COG0747	negative chemotaxis
CX039_RS06655	COG0601	transmembrane transport
CX039_RS06660	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CX039_RS06665	COG4172	Belongs to the ABC transporter superfamily
CX039_RS06670	COG1609	Transcriptional regulator
CX039_RS06700	COG0586	Pfam SNARE associated Golgi protein
CX039_RS06715	COG0500	methyltransferase
CX039_RS06730	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CX039_RS06740	COG0756	dUTP diphosphatase activity
CX039_RS06750	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CX039_RS06755	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CX039_RS06760	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CX039_RS06765	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CX039_RS06765	COG0072	phenylalanine-tRNA ligase activity
CX039_RS06770	COG0776	regulation of translation
CX039_RS06835	COG0540	Belongs to the ATCase OTCase family
CX039_RS06840	COG2974	May be involved in recombination
CX039_RS06850	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX039_RS06855	COG0583	DNA-binding transcription factor activity
CX039_RS06875	COG1028	Short-chain dehydrogenase reductase Sdr
CX039_RS06890	COG3842	ATPase activity
CX039_RS06895	COG1024	Enoyl-CoA hydratase
CX039_RS06895	COG1250	3-hydroxyacyl-CoA dehydrogenase
CX039_RS06915	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CX039_RS06920	COG2137	regulation of response to DNA damage stimulus
CX039_RS06930	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CX039_RS06940	COG0045	succinate-CoA ligase (ADP-forming) activity
CX039_RS06945	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CX039_RS06950	COG0861	Integral membrane protein TerC family
CX039_RS06955	COG0861	Integral membrane protein TerC family
CX039_RS06960	COG0181	hydroxymethylbilane synthase activity
CX039_RS07020	COG4964	Belongs to the GSP D family
CX039_RS07045	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CX039_RS07055	COG0583	DNA-binding transcription factor activity
CX039_RS07065	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CX039_RS07070	COG4311	Sarcosine oxidase, delta subunit
CX039_RS07075	COG0446	pyridine nucleotide-disulphide oxidoreductase
CX039_RS07075	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CX039_RS07110	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CX039_RS07115	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CX039_RS07120	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CX039_RS07125	COG0735	belongs to the Fur family
CX039_RS07130	COG0497	DNA recombination
CX039_RS07135	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CX039_RS07140	COG1420	regulation of RNA biosynthetic process
CX039_RS07145	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CX039_RS07155	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CX039_RS07165	COG0443	Heat shock 70 kDa protein
CX039_RS07175	COG0612	Peptidase, M16
CX039_RS07195	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CX039_RS07240	COG0745	RESPONSE REGULATOR receiver
CX039_RS07250	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CX039_RS07255	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CX039_RS07260	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CX039_RS07275	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CX039_RS07295	COG1193	negative regulation of DNA recombination
CX039_RS07300	COG0492	ferredoxin-NADP+ reductase activity
CX039_RS07305	COG1674	ftsk spoiiie
CX039_RS07310	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CX039_RS07315	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CX039_RS07320	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CX039_RS07345	COG3706	GGDEF domain
CX039_RS07365	COG2814	Major facilitator Superfamily
CX039_RS07395	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CX039_RS07410	COG1028	Short-chain dehydrogenase reductase Sdr
CX039_RS07420	COG3022	response to hydroperoxide
CX039_RS07460	COG2197	response regulator
CX039_RS07465	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CX039_RS07470	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CX039_RS07475	COG0189	ligase activity
CX039_RS07485	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CX039_RS07490	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CX039_RS07505	COG2423	ornithine cyclodeaminase activity
CX039_RS07515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CX039_RS07520	COG0765	amino acid transport
CX039_RS07525	COG0765	amino acid transport
CX039_RS07530	COG1126	abc transporter atp-binding protein
CX039_RS07585	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CX039_RS07595	COG2944	sequence-specific DNA binding
CX039_RS07605	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CX039_RS07610	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CX039_RS07615	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CX039_RS07620	COG0009	L-threonylcarbamoyladenylate synthase
CX039_RS07625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CX039_RS07630	COG1414	Transcriptional regulator
CX039_RS07645	COG0765	amino acid transport
CX039_RS07650	COG1126	abc transporter atp-binding protein
CX039_RS07655	COG0028	Belongs to the TPP enzyme family
CX039_RS07670	COG0028	Belongs to the TPP enzyme family
CX039_RS07675	COG0583	DNA-binding transcription factor activity
CX039_RS07680	COG4974	Belongs to the 'phage' integrase family
CX039_RS07685	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CX039_RS07690	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CX039_RS07705	COG1686	Belongs to the peptidase S11 family
CX039_RS07715	COG2814	Major facilitator Superfamily
CX039_RS07725	COG1074	ATP-dependent DNA helicase activity
CX039_RS07735	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CX039_RS07740	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CX039_RS07745	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CX039_RS07765	COG2321	neutral zinc metallopeptidase
CX039_RS07770	COG0009	L-threonylcarbamoyladenylate synthase
CX039_RS07815	COG3360	Dodecin
CX039_RS07820	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CX039_RS07825	COG2850	peptidyl-arginine hydroxylation
CX039_RS07830	COG3539	Fimbrial protein
CX039_RS07835	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CX039_RS07840	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CX039_RS07855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CX039_RS07860	COG0765	amino acid transport
CX039_RS07865	COG1126	abc transporter atp-binding protein
CX039_RS07870	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CX039_RS07875	COG1758	RNA polymerase activity
CX039_RS07880	COG0194	GDP metabolic process
CX039_RS07885	COG3258	Cytochrome c
CX039_RS07890	COG2863	cytochrome
CX039_RS07895	COG1028	Short-chain dehydrogenase reductase Sdr
CX039_RS07900	COG0791	NLP P60 protein
CX039_RS07905	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CX039_RS07925	COG1561	YicC-like family, N-terminal region
CX039_RS07930	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CX039_RS07950	COG2200	EAL domain
CX039_RS07950	COG2199	diguanylate cyclase activity
CX039_RS07955	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CX039_RS07965	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CX039_RS07970	COG0174	glutamine synthetase
CX039_RS07980	COG2204	response regulator
CX039_RS07985	COG0583	DNA-binding transcription factor activity
CX039_RS07990	COG1741	Belongs to the pirin family
CX039_RS07995	COG1741	Belongs to the pirin family
CX039_RS08005	COG3842	ATPase activity
CX039_RS08010	COG1178	ABC-type Fe3 transport system permease component
CX039_RS08015	COG1840	ABC-type Fe3 transport system, periplasmic component
CX039_RS08025	COG0583	DNA-binding transcription factor activity
CX039_RS08035	COG0656	L-ascorbic acid biosynthetic process
CX039_RS08050	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CX039_RS08055	COG0583	DNA-binding transcription factor activity
CX039_RS08070	COG0783	Belongs to the Dps family
CX039_RS08090	COG0463	Glycosyl transferase, family 2
CX039_RS08110	COG0438	transferase activity, transferring glycosyl groups
CX039_RS08125	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CX039_RS08150	COG0300	oxidoreductase activity
CX039_RS08195	COG0861	Integral membrane protein TerC family
CX039_RS08200	COG1028	Short-chain dehydrogenase reductase Sdr
CX039_RS08220	COG0714	Associated with various cellular activities
CX039_RS08255	COG3119	arylsulfatase activity
CX039_RS08280	COG2197	response regulator
CX039_RS08290	COG2944	sequence-specific DNA binding
CX039_RS08300	COG0625	glutathione transferase activity
CX039_RS08330	COG0179	Fumarylacetoacetate (FAA) hydrolase
CX039_RS08335	COG1028	Short-chain dehydrogenase reductase Sdr
CX039_RS08380	COG0431	NADPH-dependent FMN reductase
CX039_RS08410	COG1028	Short-chain dehydrogenase reductase Sdr
CX039_RS08415	COG0583	DNA-binding transcription factor activity
CX039_RS08435	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CX039_RS08435	COG2111	Na H antiporter
CX039_RS08440	COG1006	Multisubunit Na H antiporter MnhC subunit
CX039_RS08445	COG0651	ATP synthesis coupled electron transport
CX039_RS08450	COG1863	multisubunit Na H antiporter MnhE subunit
CX039_RS08455	COG2212	antiporter activity
CX039_RS08480	COG0590	tRNA wobble adenosine to inosine editing
CX039_RS08485	COG1619	proteins homologs of microcin C7 resistance protein MccF
CX039_RS08490	COG1024	Enoyl-CoA hydratase
CX039_RS08505	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CX039_RS08510	COG0488	(ABC) transporter
CX039_RS08555	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CX039_RS08555	COG1017	nitric oxide dioxygenase activity
CX039_RS08560	COG1959	2 iron, 2 sulfur cluster binding
CX039_RS08565	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CX039_RS08585	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CX039_RS08590	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CX039_RS08595	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CX039_RS08600	COG0084	hydrolase, TatD family'
CX039_RS08615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CX039_RS08625	COG1126	abc transporter atp-binding protein
CX039_RS08635	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CX039_RS08650	COG0028	Belongs to the TPP enzyme family
CX039_RS08660	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CX039_RS08660	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CX039_RS08670	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CX039_RS08720	COG4336	lyase activity
CX039_RS08730	COG2205	protein histidine kinase activity
CX039_RS08730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CX039_RS08735	COG2197	response regulator
CX039_RS08740	COG3064	Membrane
CX039_RS08740	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CX039_RS08740	COG3210	domain, Protein
CX039_RS08750	COG3121	Chaperone
CX039_RS08755	COG3188	usher protein
CX039_RS08760	COG3539	Fimbrial protein
CX039_RS08765	COG2831	hemolysin activation secretion protein
CX039_RS08780	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CX039_RS08830	COG0668	transmembrane transport
CX039_RS08850	COG0483	inositol monophosphate 1-phosphatase activity
CX039_RS08855	COG1253	flavin adenine dinucleotide binding
CX039_RS08860	COG1968	undecaprenyl-diphosphatase activity
CX039_RS08865	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CX039_RS08880	COG0215	cysteine-tRNA ligase activity
CX039_RS08890	COG0825	malonyl-CoA metabolic process
CX039_RS08900	COG0037	tRNA processing
CX039_RS08905	COG0527	aspartate kinase activity
CX039_RS08930	COG1250	3-hydroxyacyl-CoA dehydrogenase
CX039_RS08935	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CX039_RS08935	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CX039_RS08950	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CX039_RS08955	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
CX039_RS08960	COG1028	Short-chain dehydrogenase reductase Sdr
CX039_RS08970	COG0583	DNA-binding transcription factor activity
CX039_RS08995	COG3842	ATPase activity
CX039_RS09005	COG1902	pentaerythritol trinitrate reductase activity
CX039_RS09005	COG0446	pyridine nucleotide-disulphide oxidoreductase
CX039_RS09010	COG1414	Transcriptional regulator
CX039_RS09015	COG1832	CoA-binding protein
CX039_RS09025	COG0251	oxidation-reduction process
CX039_RS09050	COG1902	pentaerythritol trinitrate reductase activity
CX039_RS09060	COG1215	transferase activity, transferring glycosyl groups
CX039_RS09065	COG0726	polysaccharide deacetylase
CX039_RS09065	COG1649	PFAM Uncharacterised BCR, COG1649
CX039_RS09085	COG1846	Transcriptional regulator
CX039_RS09090	COG2197	response regulator
CX039_RS09105	COG0166	Belongs to the GPI family
CX039_RS09110	COG1045	serine acetyltransferase
CX039_RS09120	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CX039_RS09125	COG0483	inositol monophosphate 1-phosphatase activity
CX039_RS09130	COG1012	belongs to the aldehyde dehydrogenase family
CX039_RS09135	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CX039_RS09150	COG0210	DNA helicase
CX039_RS09155	COG0598	Magnesium transport protein CorA
CX039_RS09165	COG0747	negative chemotaxis
CX039_RS09170	COG0601	transmembrane transport
CX039_RS09175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CX039_RS09180	COG4172	Belongs to the ABC transporter superfamily
CX039_RS09185	COG1846	Transcriptional regulator
CX039_RS09240	COG4964	Belongs to the GSP D family
CX039_RS09280	COG2204	response regulator
CX039_RS09295	COG1595	DNA-templated transcription, initiation
CX039_RS09305	COG3474	cytochrome
CX039_RS09310	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CX039_RS09325	COG3384	dioxygenase
CX039_RS09330	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CX039_RS09360	COG2885	chlorophyll binding
CX039_RS09395	COG0697	spore germination
CX039_RS09400	COG0730	response to heat
CX039_RS09420	COG0583	DNA-binding transcription factor activity
CX039_RS09425	COG0427	acetyl-CoA hydrolase
CX039_RS09480	COG1250	3-hydroxyacyl-CoA dehydrogenase
CX039_RS09485	COG0154	amidase activity
CX039_RS09495	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CX039_RS09510	COG0495	leucyl-tRNA aminoacylation
CX039_RS09515	COG2814	Major facilitator Superfamily
CX039_RS09550	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CX039_RS09555	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CX039_RS09560	COG2814	Major facilitator Superfamily
CX039_RS09580	COG4176	ABC-type proline glycine betaine transport system permease component
CX039_RS09590	COG1942	4-Oxalocrotonate Tautomerase
CX039_RS09595	COG0183	Belongs to the thiolase family
CX039_RS09605	COG1802	Transcriptional regulator
CX039_RS09615	COG1024	Enoyl-CoA hydratase
CX039_RS09630	COG2032	superoxide dismutase activity
CX039_RS09645	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CX039_RS09670	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CX039_RS09675	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CX039_RS09685	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CX039_RS09690	COG0736	holo-[acyl-carrier-protein] synthase activity
CX039_RS09695	COG1472	Belongs to the glycosyl hydrolase 3 family
CX039_RS09700	COG0322	excinuclease ABC activity
CX039_RS09705	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CX039_RS09715	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CX039_RS09715	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CX039_RS09720	COG2224	Isocitrate lyase
CX039_RS09745	COG0559	Belongs to the binding-protein-dependent transport system permease family
CX039_RS09755	COG4638	Rieske (2fe-2S)
CX039_RS09765	COG1024	Enoyl-CoA hydratase
CX039_RS09775	COG0633	Ferredoxin
CX039_RS09780	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX039_RS09795	COG0183	Belongs to the thiolase family
CX039_RS09810	COG0583	DNA-binding transcription factor activity
CX039_RS09840	COG2346	COG2346, Truncated hemoglobins
CX039_RS09970	COG2207	Transcriptional regulator
CX039_RS10015	COG1132	(ABC) transporter
CX039_RS10040	COG0659	secondary active sulfate transmembrane transporter activity
CX039_RS10070	COG2169	Transcriptional regulator
CX039_RS10075	COG5507	3-demethylubiquinone-9 3-methyltransferase
CX039_RS10080	COG0384	phenazine biosynthesis protein PhzF
CX039_RS10085	COG0583	DNA-binding transcription factor activity
CX039_RS10090	COG2733	membrane
CX039_RS10105	COG1012	belongs to the aldehyde dehydrogenase family
CX039_RS10110	COG3284	Transcriptional regulator
CX039_RS10135	COG1380	Effector of murein hydrolase LrgA
CX039_RS10140	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CX039_RS10140	COG4106	trans-aconitate 2-methyltransferase activity
CX039_RS10150	COG0156	8-amino-7-oxononanoate synthase activity
CX039_RS10220	COG1131	(ABC) transporter
CX039_RS10225	COG0842	Transport permease protein
CX039_RS10230	COG0628	permease
CX039_RS10265	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CX039_RS10275	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CX039_RS10280	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CX039_RS10285	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CX039_RS10290	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CX039_RS10295	COG0330	HflC and HflK could
CX039_RS10300	COG0330	HflC and HflK could
CX039_RS10305	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CX039_RS10310	COG1923	regulation of RNA biosynthetic process
CX039_RS10315	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CX039_RS10320	COG1160	GTP binding
CX039_RS10325	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CX039_RS10330	COG2976	Protein conserved in bacteria
CX039_RS10335	COG0124	histidyl-tRNA synthetase
CX039_RS10340	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CX039_RS10350	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CX039_RS10355	COG0105	UTP biosynthetic process
CX039_RS10360	COG0525	valine-tRNA ligase activity
CX039_RS10375	COG0642	Histidine kinase
CX039_RS10400	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CX039_RS10405	COG0336	Belongs to the RNA methyltransferase TrmD family
CX039_RS10410	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CX039_RS10415	COG0228	four-way junction DNA binding
CX039_RS10425	COG0425	Belongs to the sulfur carrier protein TusA family
CX039_RS10430	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CX039_RS10475	COG0154	amidase activity
CX039_RS10480	COG4172	Belongs to the ABC transporter superfamily
CX039_RS10485	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CX039_RS10490	COG0601	transmembrane transport
CX039_RS10495	COG0747	negative chemotaxis
CX039_RS10525	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CX039_RS10535	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CX039_RS10555	COG3395	kinase activity
CX039_RS10570	COG1024	Enoyl-CoA hydratase
CX039_RS10590	COG0633	Ferredoxin
CX039_RS10595	COG0443	Heat shock 70 kDa protein
CX039_RS10600	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CX039_RS10605	COG0316	Belongs to the HesB IscA family
CX039_RS10610	COG0822	iron-sulfur transferase activity
CX039_RS10615	COG1104	cysteine desulfurase activity
CX039_RS10625	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CX039_RS10630	COG0556	nucleotide-excision repair
CX039_RS10640	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CX039_RS10670	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CX039_RS10690	COG1028	Short-chain dehydrogenase reductase Sdr
CX039_RS10695	COG0183	Belongs to the thiolase family
CX039_RS10705	COG1024	Enoyl-CoA hydratase
CX039_RS10720	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX039_RS10725	COG0583	DNA-binding transcription factor activity
CX039_RS10730	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CX039_RS10735	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CX039_RS10740	COG0740	serine-type endopeptidase activity
CX039_RS10745	COG0544	peptidyl-prolyl cis-trans isomerase activity
CX039_RS10755	COG1278	Cold shock
CX039_RS10765	COG1278	Cold shock
CX039_RS10800	COG2171	N-acyltransferase activity
CX039_RS10805	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CX039_RS10810	COG2890	protein-(glutamine-N5) methyltransferase activity
CX039_RS10815	COG0488	(ABC) transporter
CX039_RS10820	COG4771	TonB-dependent receptor
CX039_RS10825	COG0210	DNA helicase
CX039_RS10845	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CX039_RS10850	COG0196	riboflavin kinase activity
CX039_RS10855	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CX039_RS10860	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CX039_RS10865	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CX039_RS10875	COG1522	sequence-specific DNA binding
CX039_RS10895	COG2951	lytic endotransglycosylase activity
CX039_RS10900	COG2833	Protein of unknown function (DUF455)
CX039_RS10920	COG0189	ligase activity
CX039_RS10920	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CX039_RS10925	COG1181	Belongs to the D-alanine--D-alanine ligase family
CX039_RS10925	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CX039_RS10930	COG3237	CsbD-like
CX039_RS10940	COG2823	Periplasmic or secreted lipoprotein
CX039_RS10965	COG4181	ATPase activity
CX039_RS10975	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CX039_RS10980	COG0584	glycerophosphoryl diester phosphodiesterase
CX039_RS10985	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CX039_RS10995	COG0678	peroxiredoxin activity
CX039_RS10995	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CX039_RS11005	COG0789	Transcriptional regulator
CX039_RS11010	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CX039_RS11040	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CX039_RS11045	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CX039_RS11055	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CX039_RS11060	COG2252	PERMEase
CX039_RS11070	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CX039_RS11100	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CX039_RS11105	COG2358	TRAP transporter, solute receptor (TAXI family
CX039_RS11140	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CX039_RS11145	COG1366	Belongs to the anti-sigma-factor antagonist family
CX039_RS11150	COG2172	sigma factor antagonist activity
CX039_RS11155	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CX039_RS11165	COG2208	phosphoserine phosphatase activity
CX039_RS11165	COG2770	Histidine kinase
CX039_RS11190	COG1595	DNA-templated transcription, initiation
CX039_RS11205	COG4792	protein secretion
CX039_RS11210	COG4791	protein targeting
CX039_RS11215	COG4794	Type iii secretion
CX039_RS11220	COG4790	Type iii secretion
CX039_RS11255	COG4669	(LipO)protein
CX039_RS11320	COG4789	Type iii secretion
CX039_RS11350	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CX039_RS11355	COG0840	transmembrane signaling receptor activity
CX039_RS11360	COG2233	PERMEase
CX039_RS11390	COG1840	ABC-type Fe3 transport system, periplasmic component
CX039_RS11395	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CX039_RS11400	COG1178	ABC-type Fe3 transport system permease component
CX039_RS11405	COG3842	ATPase activity
CX039_RS11410	COG0583	DNA-binding transcription factor activity
CX039_RS11430	COG0501	Belongs to the peptidase M48B family
CX039_RS11440	COG0697	spore germination
CX039_RS11450	COG1846	Transcriptional regulator
CX039_RS11460	COG1566	PFAM secretion protein HlyD family protein
CX039_RS11465	COG2814	Major facilitator Superfamily
CX039_RS11470	COG0473	3-isopropylmalate dehydrogenase activity
CX039_RS11480	COG0747	negative chemotaxis
CX039_RS11490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CX039_RS11505	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CX039_RS11530	COG1012	belongs to the aldehyde dehydrogenase family
CX039_RS11540	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CX039_RS11545	COG1115	amino acid carrier protein
CX039_RS11550	COG0433	COG0433 Predicted ATPase
CX039_RS11555	COG0217	transcriptional regulatory protein
CX039_RS11560	COG0151	Belongs to the GarS family
CX039_RS11565	COG0408	coproporphyrinogen oxidase activity
CX039_RS11570	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CX039_RS11575	COG0799	negative regulation of ribosome biogenesis
CX039_RS11580	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CX039_RS11585	COG0424	maF-like protein
CX039_RS11590	COG3468	outer membrane autotransporter barrel domain protein
CX039_RS11630	COG1530	ribonuclease E activity
CX039_RS11635	COG0077	Prephenate dehydratase
CX039_RS11650	COG1132	(ABC) transporter
CX039_RS11655	COG0859	PFAM glycosyl transferase family 9
CX039_RS11680	COG2194	sulfuric ester hydrolase activity
CX039_RS11685	COG0438	transferase activity, transferring glycosyl groups
CX039_RS11690	COG0463	Glycosyl transferase, family 2
CX039_RS11695	COG0726	polysaccharide deacetylase
CX039_RS11700	COG0438	transferase activity, transferring glycosyl groups
CX039_RS11715	COG1643	Atp-dependent helicase
CX039_RS11720	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CX039_RS11720	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CX039_RS11725	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CX039_RS11735	COG0704	Plays a role in the regulation of phosphate uptake
CX039_RS11740	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CX039_RS11745	COG1960	acyl-CoA dehydrogenase activity
CX039_RS11770	COG1177	transmembrane transport
CX039_RS11775	COG1176	ABC-type spermidine putrescine transport system, permease component I
CX039_RS11780	COG3842	ATPase activity
CX039_RS11785	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CX039_RS11800	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CX039_RS11805	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CX039_RS11815	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CX039_RS11815	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CX039_RS11830	COG0372	Belongs to the citrate synthase family
CX039_RS11835	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CX039_RS11840	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CX039_RS11845	COG1053	succinate dehydrogenase
CX039_RS11850	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CX039_RS11855	COG2009	succinate dehydrogenase
CX039_RS11860	COG2188	Transcriptional regulator
CX039_RS11865	COG0039	L-malate dehydrogenase activity
CX039_RS11895	COG1981	membrane
CX039_RS11920	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CX039_RS11930	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CX039_RS11960	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CX039_RS11965	COG0148	phosphopyruvate hydratase activity
CX039_RS11975	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CX039_RS11980	COG0504	CTP synthase activity
CX039_RS12005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CX039_RS12015	COG0747	negative chemotaxis
CX039_RS12020	COG4172	Belongs to the ABC transporter superfamily
CX039_RS12025	COG1446	asparaginase
CX039_RS12055	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CX039_RS12070	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CX039_RS12075	COG0697	spore germination
CX039_RS12080	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CX039_RS12090	COG3193	protein, possibly involved in utilization of glycolate and propanediol
CX039_RS12100	COG0791	NLP P60 protein
CX039_RS12115	COG0583	DNA-binding transcription factor activity
CX039_RS12130	COG0583	DNA-binding transcription factor activity
CX039_RS12140	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CX039_RS12155	COG0670	Belongs to the BI1 family
CX039_RS12160	COG3181	Tripartite tricarboxylate transporter family receptor
CX039_RS12175	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CX039_RS12185	COG1381	Involved in DNA repair and RecF pathway recombination
CX039_RS12190	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CX039_RS12195	COG0571	ribonuclease III activity
CX039_RS12200	COG0681	Belongs to the peptidase S26 family
CX039_RS12205	COG0481	GTPase activity
CX039_RS12210	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CX039_RS12235	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CX039_RS12240	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CX039_RS12255	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CX039_RS12260	COG0416	fatty acid biosynthetic process
CX039_RS12265	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CX039_RS12270	COG1399	metal-binding, possibly nucleic acid-binding protein
CX039_RS12275	COG0424	maF-like protein
CX039_RS12285	COG3023	N-Acetylmuramoyl-L-alanine amidase
CX039_RS12300	COG3022	response to hydroperoxide
CX039_RS12315	COG0135	phosphoribosylanthranilate isomerase activity
CX039_RS12330	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CX039_RS12335	COG0101	tRNA pseudouridine synthase activity
CX039_RS12345	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CX039_RS12350	COG0473	3-isopropylmalate dehydrogenase activity
CX039_RS12355	COG0066	3-isopropylmalate dehydratase activity
CX039_RS12360	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CX039_RS12370	COG1122	ATPase activity
CX039_RS12405	COG3383	formate dehydrogenase (NAD+) activity
CX039_RS12405	COG0243	molybdopterin cofactor binding
CX039_RS12435	COG0489	protein tyrosine kinase activity
CX039_RS12440	COG0746	molybdenum cofactor guanylyltransferase activity
CX039_RS12445	COG0303	'Molybdopterin
CX039_RS12450	COG1763	Mo-molybdopterin cofactor biosynthetic process
CX039_RS12460	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CX039_RS12465	COG5001	Diguanylate cyclase
CX039_RS12485	COG3842	ATPase activity
CX039_RS12495	COG0406	alpha-ribazole phosphatase activity
CX039_RS12505	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CX039_RS12510	COG0505	Belongs to the CarA family
CX039_RS12515	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CX039_RS12550	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CX039_RS12555	COG1960	acyl-CoA dehydrogenase activity
CX039_RS12565	COG2867	negative regulation of translational initiation
CX039_RS12575	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CX039_RS12580	COG3706	GGDEF domain
CX039_RS12585	COG0330	HflC and HflK could
CX039_RS12600	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CX039_RS12600	COG0519	Catalyzes the synthesis of GMP from XMP
CX039_RS12610	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CX039_RS12615	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CX039_RS12620	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CX039_RS12625	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CX039_RS12635	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CX039_RS12640	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CX039_RS12645	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CX039_RS12650	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CX039_RS12655	COG0750	zinc metalloprotease
CX039_RS12660	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CX039_RS12670	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CX039_RS12675	COG0233	cytoplasmic translational termination
CX039_RS12680	COG0528	UMP kinase activity
CX039_RS12685	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CX039_RS12690	COG0052	Belongs to the universal ribosomal protein uS2 family
CX039_RS12695	COG0024	Methionine aminopeptidase
CX039_RS12700	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CX039_RS12730	COG0285	dihydrofolate synthase activity
CX039_RS12765	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CX039_RS12775	COG1677	Flagellar hook-basal body complex protein FliE
CX039_RS12785	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CX039_RS12795	COG1157	protein secretion by the type III secretion system
CX039_RS12820	COG1580	Controls the rotational direction of flagella during chemotaxis
CX039_RS12840	COG1338	Plays a role in the flagellum-specific transport system
CX039_RS12860	COG0840	transmembrane signaling receptor activity
CX039_RS12865	COG0840	transmembrane signaling receptor activity
CX039_RS12870	COG0840	transmembrane signaling receptor activity
CX039_RS12880	COG1256	bacterial-type flagellum assembly
CX039_RS12890	COG1706	bacterial-type flagellum-dependent cell motility
CX039_RS12895	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CX039_RS12910	COG1749	Flagellar hook protein flgE
CX039_RS12920	COG1558	bacterial-type flagellum-dependent cell motility
CX039_RS12925	COG1815	bacterial-type flagellum-dependent cell motility
CX039_RS12965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CX039_RS12970	COG0765	amino acid transport
CX039_RS12975	COG1126	abc transporter atp-binding protein
CX039_RS12990	COG4948	Mandelate Racemase Muconate Lactonizing
CX039_RS12995	COG3181	Tripartite tricarboxylate transporter family receptor
CX039_RS13005	COG0066	3-isopropylmalate dehydratase activity
CX039_RS13020	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX039_RS13030	COG3181	Tripartite tricarboxylate transporter family receptor
CX039_RS13040	COG1802	Transcriptional regulator
CX039_RS13055	COG0583	DNA-binding transcription factor activity
CX039_RS13075	COG1695	Transcriptional regulator
CX039_RS13085	COG3568	Endonuclease Exonuclease Phosphatase
CX039_RS13090	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CX039_RS13140	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CX039_RS13150	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CX039_RS13170	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CX039_RS13200	COG0667	Aldo Keto reductase
CX039_RS13215	COG2259	Doxx family
CX039_RS13245	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX039_RS13265	COG0386	Belongs to the glutathione peroxidase family
CX039_RS13270	COG0625	glutathione transferase activity
CX039_RS13285	COG0095	Lipoate-protein ligase
CX039_RS13300	COG0688	phosphatidylethanolamine metabolic process
CX039_RS13310	COG1464	Belongs to the NlpA lipoprotein family
CX039_RS13325	COG2363	Small membrane protein
CX039_RS13350	COG3842	ATPase activity
CX039_RS13355	COG0395	ABC-type sugar transport system, permease component
CX039_RS13360	COG1175	transmembrane transport
CX039_RS13365	COG1653	transport
CX039_RS13375	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CX039_RS13395	COG0559	Belongs to the binding-protein-dependent transport system permease family
CX039_RS13415	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CX039_RS13440	COG2311	Membrane
CX039_RS13465	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CX039_RS13475	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CX039_RS13480	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CX039_RS13485	COG1760	l-serine dehydratase
CX039_RS13490	COG1283	sodium-dependent phosphate transmembrane transporter activity
CX039_RS13495	COG0412	Dienelactone hydrolase
CX039_RS13510	COG1611	Belongs to the LOG family
CX039_RS13530	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CX039_RS13535	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CX039_RS13540	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CX039_RS13545	COG0195	Participates in both transcription termination and antitermination
CX039_RS13545	COG2251	uridine kinase activity
CX039_RS13550	COG0779	Required for maturation of 30S ribosomal subunits
CX039_RS13555	COG1187	pseudouridine synthase activity
CX039_RS13560	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CX039_RS13570	COG0583	DNA-binding transcription factor activity
CX039_RS13580	COG0523	cobalamin synthesis protein
CX039_RS13600	COG0625	glutathione transferase activity
CX039_RS13605	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CX039_RS13610	COG1047	Peptidyl-prolyl cis-trans
CX039_RS13615	COG2003	Belongs to the UPF0758 family
CX039_RS13620	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CX039_RS13625	COG3483	tryptophan 2,3-dioxygenase activity
CX039_RS13630	COG0254	rRNA binding
CX039_RS13640	COG0534	Mate efflux family protein
CX039_RS13660	COG2304	oxidoreductase activity
CX039_RS13680	COG1028	Short-chain dehydrogenase reductase Sdr
CX039_RS13685	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CX039_RS13690	COG1562	ergosterol biosynthetic process
CX039_RS13695	COG1562	ergosterol biosynthetic process
CX039_RS13700	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CX039_RS13700	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CX039_RS13705	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CX039_RS13715	COG0842	Transport permease protein
CX039_RS13720	COG1131	(ABC) transporter
CX039_RS13740	COG1477	protein flavinylation
CX039_RS13755	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CX039_RS13770	COG5564	TIM-barrel signal transduction protein
CX039_RS13775	COG5441	Belongs to the UPF0261 family
CX039_RS13785	COG3468	outer membrane autotransporter barrel domain protein
CX039_RS13805	COG0542	response to heat
CX039_RS13810	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CX039_RS13825	COG0494	nUDIX hydrolase
CX039_RS13830	COG3530	Putative quorum-sensing-regulated virulence factor
CX039_RS13840	COG1595	DNA-templated transcription, initiation
CX039_RS13845	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CX039_RS13880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CX039_RS13885	COG0765	amino acid transport
CX039_RS13890	COG0765	amino acid transport
CX039_RS13915	COG2988	succinylglutamate desuccinylase activity
CX039_RS13940	COG3181	Tripartite tricarboxylate transporter family receptor
CX039_RS13945	COG2084	Dehydrogenase
CX039_RS13960	COG1619	proteins homologs of microcin C7 resistance protein MccF
CX039_RS13975	COG2814	Major facilitator Superfamily
CX039_RS13985	COG0583	DNA-binding transcription factor activity
CX039_RS14025	COG0672	)-iron permease
CX039_RS14040	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
CX039_RS14045	COG1028	Short-chain dehydrogenase reductase Sdr
CX039_RS14050	COG3243	poly(R)-hydroxyalkanoic acid synthase
CX039_RS14060	COG0564	pseudouridine synthase activity
CX039_RS14070	COG1199	ATP-dependent helicase activity
CX039_RS14075	COG2183	response to ionizing radiation
CX039_RS14080	COG0180	Tryptophanyl-tRNA synthetase
CX039_RS14105	COG3181	Tripartite tricarboxylate transporter family receptor
CX039_RS14115	COG0583	DNA-binding transcription factor activity
CX039_RS14120	COG1028	Short-chain dehydrogenase reductase Sdr
CX039_RS14125	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CX039_RS14130	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CX039_RS14135	COG0508	dehydrogenase complex catalyzes the overall conversion of
CX039_RS14140	COG0567	Dehydrogenase, E1 component
CX039_RS14150	COG1522	sequence-specific DNA binding
CX039_RS14160	COG0280	phosphate acetyltransferase
CX039_RS14160	COG0281	malic enzyme
CX039_RS14165	COG3539	Fimbrial protein
CX039_RS14185	COG0613	PHP domain protein
CX039_RS14195	COG2333	competence protein COMEC
CX039_RS14195	COG0658	competence protein
CX039_RS14220	COG0084	hydrolase, TatD family'
CX039_RS14225	COG1136	(ABC) transporter
CX039_RS14240	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CX039_RS14250	COG1028	Short-chain dehydrogenase reductase Sdr
CX039_RS14255	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CX039_RS14270	COG1022	Amp-dependent synthetase and ligase
CX039_RS14305	COG2205	protein histidine kinase activity
CX039_RS14310	COG0745	RESPONSE REGULATOR receiver
CX039_RS14315	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CX039_RS14325	COG1295	ribonuclease BN
CX039_RS14340	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CX039_RS14370	COG1534	Rna-binding protein
CX039_RS14375	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CX039_RS14380	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CX039_RS14390	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CX039_RS14400	COG0248	Ppx GppA phosphatase
CX039_RS14425	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CX039_RS14440	COG2732	(Barnase) inhibitor
CX039_RS14450	COG0281	malic enzyme
CX039_RS14450	COG0280	phosphate acetyltransferase
CX039_RS14460	COG0436	Aminotransferase
CX039_RS14470	COG0741	lytic transglycosylase activity
CX039_RS14475	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CX039_RS14500	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CX039_RS14500	COG1648	precorrin-2 dehydrogenase activity
CX039_RS14525	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CX039_RS14530	COG2027	D-alanyl-D-alanine carboxypeptidase
CX039_RS14535	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CX039_RS14540	COG0343	queuine tRNA-ribosyltransferase activity
CX039_RS14545	COG1862	Preprotein translocase
CX039_RS14550	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CX039_RS14555	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CX039_RS14570	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CX039_RS14575	COG1702	phosphate starvation-inducible protein PhoH
CX039_RS14580	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CX039_RS14585	COG4535	Mg2 and Co2 transporter CorC
CX039_RS14595	COG0667	Aldo Keto reductase
CX039_RS14620	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CX039_RS14625	COG0745	RESPONSE REGULATOR receiver
CX039_RS14630	COG2201	protein-glutamate methylesterase activity
CX039_RS14640	COG0840	transmembrane signaling receptor activity
CX039_RS14655	COG0745	RESPONSE REGULATOR receiver
CX039_RS14690	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CX039_RS14700	COG0739	heme binding
CX039_RS14710	COG0521	Mo-molybdopterin cofactor biosynthetic process
CX039_RS14720	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CX039_RS14750	COG0625	glutathione transferase activity
CX039_RS14765	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CX039_RS14770	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CX039_RS14775	COG0126	phosphoglycerate kinase activity
CX039_RS14780	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CX039_RS14785	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CX039_RS14790	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CX039_RS14805	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CX039_RS14810	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CX039_RS14815	COG0508	dehydrogenase complex catalyzes the overall conversion of
CX039_RS14820	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CX039_RS14830	COG4566	intracellular signal transduction
CX039_RS14835	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CX039_RS14840	COG0339	signal peptide processing
CX039_RS14845	COG1999	signal sequence binding
CX039_RS14875	COG1187	pseudouridine synthase activity
CX039_RS14880	COG3161	chorismate lyase activity
CX039_RS14895	COG0667	Aldo Keto reductase
CX039_RS14910	COG0335	large ribosomal subunit rRNA binding
CX039_RS14945	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CX039_RS14965	COG0450	alkyl hydroperoxide reductase
CX039_RS14970	COG1960	acyl-CoA dehydrogenase activity
CX039_RS14985	COG0123	including yeast histone deacetylase and acetoin utilization protein
CX039_RS14990	COG2951	lytic endotransglycosylase activity
CX039_RS15005	COG1596	polysaccharide export
CX039_RS15005	COG1555	photosystem II stabilization
CX039_RS15010	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CX039_RS15015	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CX039_RS15020	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CX039_RS15040	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CX039_RS15045	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CX039_RS15050	COG0287	Prephenate dehydrogenase
CX039_RS15060	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CX039_RS15075	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CX039_RS15085	COG2814	Major facilitator Superfamily
CX039_RS15120	COG0583	DNA-binding transcription factor activity
CX039_RS15160	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CX039_RS15175	COG0667	Aldo Keto reductase
CX039_RS15185	COG5265	(ABC) transporter
CX039_RS15235	COG0439	Biotin carboxylase
CX039_RS15240	COG2188	Transcriptional regulator
CX039_RS15265	COG0511	ligase activity, forming carbon-carbon bonds
CX039_RS15275	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CX039_RS15295	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CX039_RS15315	COG0500	methyltransferase
CX039_RS15320	COG5265	(ABC) transporter
CX039_RS15335	COG0028	Belongs to the TPP enzyme family
CX039_RS15340	COG0440	acetolactate synthase activity
CX039_RS15345	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CX039_RS15350	COG1183	phosphatidylcholine synthase activity
CX039_RS15365	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CX039_RS15370	COG1185	polyribonucleotide nucleotidyltransferase activity
CX039_RS15385	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CX039_RS15405	COG0149	triose-phosphate isomerase activity
CX039_RS15410	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CX039_RS15420	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CX039_RS15430	COG3799	methylaspartate ammonia-lyase activity
CX039_RS15465	COG0583	DNA-binding transcription factor activity
CX039_RS15470	COG0626	cystathionine gamma-synthase activity
CX039_RS15475	COG3608	succinylglutamate desuccinylase aspartoacylase
CX039_RS15495	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CX039_RS15515	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
CX039_RS15530	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CX039_RS15535	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CX039_RS15540	COG1733	regulation of RNA biosynthetic process
CX039_RS15555	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CX039_RS15560	COG0583	DNA-binding transcription factor activity
CX039_RS15565	COG1597	lipid kinase activity
CX039_RS15575	COG0671	phosphoesterase, PA-phosphatase related
CX039_RS15605	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CX039_RS15610	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CX039_RS15615	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CX039_RS15620	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CX039_RS15625	COG0649	NAD binding
CX039_RS15630	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CX039_RS15640	COG1034	ATP synthesis coupled electron transport
CX039_RS15645	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CX039_RS15650	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CX039_RS15660	COG0713	ATP synthesis coupled electron transport
CX039_RS15675	COG1007	ATP synthesis coupled electron transport
CX039_RS15685	COG4774	siderophore transport
CX039_RS15690	COG4774	siderophore transport
CX039_RS15705	COG0028	Belongs to the TPP enzyme family
CX039_RS15710	COG3181	Tripartite tricarboxylate transporter family receptor
CX039_RS15715	COG0583	DNA-binding transcription factor activity
CX039_RS15720	COG0560	Phosphoserine phosphatase
CX039_RS15725	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CX039_RS15730	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CX039_RS15735	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CX039_RS15750	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CX039_RS15755	COG0308	aminopeptidase N
CX039_RS15775	COG0028	Belongs to the TPP enzyme family
CX039_RS15795	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CX039_RS15805	COG0318	PFAM AMP-dependent synthetase and ligase
CX039_RS15815	COG1802	Transcriptional regulator
CX039_RS15825	COG1802	Transcriptional regulator
CX039_RS15835	COG1028	Short-chain dehydrogenase reductase Sdr
CX039_RS15855	COG1126	abc transporter atp-binding protein
CX039_RS15860	COG0765	amino acid transport
CX039_RS15880	COG1538	Outer membrane efflux protein
CX039_RS15885	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CX039_RS15890	COG2274	protein secretion by the type I secretion system
CX039_RS15895	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CX039_RS15905	COG2994	toxin metabolic process
CX039_RS15925	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CX039_RS15930	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
CX039_RS15940	COG0583	DNA-binding transcription factor activity
CX039_RS15950	COG0142	geranyltranstransferase activity
CX039_RS15960	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CX039_RS15965	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CX039_RS15970	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CX039_RS15975	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CX039_RS16020	COG3712	iron ion homeostasis
CX039_RS16025	COG4774	siderophore transport
CX039_RS16030	COG2353	YceI-like domain
CX039_RS16045	COG0019	diaminopimelate decarboxylase activity
CX039_RS16065	COG0747	negative chemotaxis
CX039_RS16070	COG0601	transmembrane transport
CX039_RS16075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CX039_RS16085	COG0154	amidase activity
CX039_RS16090	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CX039_RS16115	COG2154	pterin-4-alpha-carbinolamine dehydratase
CX039_RS16125	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CX039_RS16135	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CX039_RS16140	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CX039_RS16145	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CX039_RS16150	COG1929	Belongs to the glycerate kinase type-1 family
CX039_RS16155	COG0469	pyruvate kinase activity
CX039_RS16160	COG0700	Nucleoside recognition
CX039_RS16195	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CX039_RS16200	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CX039_RS16215	COG0823	Involved in the tonB-independent uptake of proteins
CX039_RS16225	COG0848	biopolymer transport protein
CX039_RS16230	COG0811	peptide transport
CX039_RS16235	COG0824	Thioesterase
CX039_RS16240	COG0442	prolyl-tRNA aminoacylation
CX039_RS16245	COG0494	nUDIX hydrolase
CX039_RS16260	COG2135	peptidase activity
CX039_RS16335	COG1196	nuclear chromosome segregation
CX039_RS16475	COG1464	Belongs to the NlpA lipoprotein family
CX039_RS16505	COG4211	Belongs to the binding-protein-dependent transport system permease family
CX039_RS16515	COG0154	amidase activity
CX039_RS16520	COG0288	reversible hydration of carbon dioxide
CX039_RS16535	COG0514	ATP-dependent DNA helicase (RecQ)
CX039_RS16540	COG2255	four-way junction helicase activity
CX039_RS16555	COG0632	four-way junction helicase activity
CX039_RS16560	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CX039_RS16580	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CX039_RS16590	COG0006	proline dipeptidase activity
CX039_RS16615	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CX039_RS16630	COG4783	chaperone-mediated protein folding
CX039_RS16635	COG0429	hydrolase of the alpha beta-hydrolase fold
CX039_RS16665	COG0513	Belongs to the DEAD box helicase family
CX039_RS16685	COG1546	Belongs to the CinA family
CX039_RS16685	COG1058	Belongs to the CinA family
CX039_RS16690	COG1414	Transcriptional regulator
CX039_RS16710	COG0167	dihydroorotate dehydrogenase activity
CX039_RS16715	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CX039_RS16730	COG0583	DNA-binding transcription factor activity
CX039_RS16790	COG0280	phosphate acetyltransferase
CX039_RS16790	COG0281	malic enzyme
CX039_RS16800	COG0601	transmembrane transport
CX039_RS16805	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CX039_RS16810	COG4172	Belongs to the ABC transporter superfamily
CX039_RS16840	COG0640	Transcriptional regulator
CX039_RS16855	COG3135	benzoate transporter
CX039_RS16860	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CX039_RS16865	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CX039_RS16870	COG0742	ribosomal rna small subunit methyltransferase
CX039_RS16885	COG3639	organic phosphonate transmembrane transporter activity
CX039_RS16890	COG3639	organic phosphonate transmembrane transporter activity
CX039_RS16930	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CX039_RS16935	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CX039_RS16945	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CX039_RS16950	COG1546	Belongs to the CinA family
CX039_RS16950	COG1058	Belongs to the CinA family
CX039_RS16955	COG0284	orotidine-5'-phosphate decarboxylase activity
CX039_RS16960	COG1252	NADH dehydrogenase
CX039_RS16975	COG3468	outer membrane autotransporter barrel domain protein
CX039_RS16980	COG0459	protein refolding
CX039_RS16985	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CX039_RS17005	COG1053	succinate dehydrogenase
CX039_RS17020	COG0583	DNA-binding transcription factor activity
CX039_RS17025	COG1053	succinate dehydrogenase
CX039_RS17050	COG3706	GGDEF domain
CX039_RS17090	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
CX039_RS17100	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CX039_RS17110	COG0069	glutamate synthase activity
CX039_RS17115	COG2391	methyltransferase activity
CX039_RS17120	COG0679	Auxin Efflux Carrier
CX039_RS17145	COG0557	exoribonuclease II activity
CX039_RS17150	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CX039_RS17160	COG3128	pkhd-type hydroxylase
CX039_RS17165	COG0776	regulation of translation
CX039_RS17195	COG0642	Histidine kinase
CX039_RS17200	COG3158	transport of potassium into the cell
CX039_RS17205	COG0137	argininosuccinate synthase activity
CX039_RS17210	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CX039_RS17215	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CX039_RS17225	COG0583	DNA-binding transcription factor activity
CX039_RS17235	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CX039_RS17255	COG2186	Transcriptional regulator
CX039_RS17265	COG2223	nitrite transmembrane transporter activity
CX039_RS17275	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CX039_RS17280	COG0450	alkyl hydroperoxide reductase
CX039_RS17300	COG1214	PFAM Peptidase M22, glycoprotease
CX039_RS17305	COG1573	uracil-dna glycosylase
CX039_RS17310	COG0477	Major facilitator Superfamily
CX039_RS17315	COG1196	nuclear chromosome segregation
CX039_RS17325	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CX039_RS17330	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CX039_RS17345	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CX039_RS17350	COG1122	ATPase activity
CX039_RS17355	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CX039_RS17360	COG1268	BioY protein
CX039_RS17380	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CX039_RS17415	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CX039_RS17420	COG2878	Part of a membrane complex involved in electron transport
CX039_RS17435	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CX039_RS17440	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CX039_RS17445	COG0251	oxidation-reduction process
CX039_RS17455	COG3228	Belongs to the MtfA family
CX039_RS17460	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CX039_RS17470	COG0133	tryptophan synthase activity
CX039_RS17475	COG0159	tryptophan synthase activity
CX039_RS17480	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CX039_RS17500	COG1530	ribonuclease E activity
CX039_RS17510	COG0546	phosphoglycolate phosphatase activity
CX039_RS17515	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CX039_RS17520	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CX039_RS17535	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX039_RS17540	COG0583	DNA-binding transcription factor activity
CX039_RS17550	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX039_RS17570	COG0251	oxidation-reduction process
CX039_RS17575	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CX039_RS17575	COG1017	nitric oxide dioxygenase activity
CX039_RS17580	COG2031	fatty acid transporter
CX039_RS17585	COG1012	belongs to the aldehyde dehydrogenase family
CX039_RS17590	COG1802	Transcriptional regulator
CX039_RS17600	COG1278	Cold shock
CX039_RS17605	COG0583	DNA-binding transcription factor activity
CX039_RS17630	COG0183	Belongs to the thiolase family
CX039_RS17640	COG1960	acyl-CoA dehydrogenase activity
CX039_RS17645	COG0583	DNA-binding transcription factor activity
CX039_RS17650	COG3181	Tripartite tricarboxylate transporter family receptor
CX039_RS17655	COG1024	Enoyl-CoA hydratase
CX039_RS17660	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX039_RS17665	COG1253	flavin adenine dinucleotide binding
CX039_RS17670	COG1285	pathogenesis
CX039_RS17680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CX039_RS17695	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CX039_RS17710	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CX039_RS17725	COG2031	fatty acid transporter
CX039_RS17735	COG0786	glutamate:sodium symporter activity
CX039_RS17750	COG0463	Glycosyl transferase, family 2
CX039_RS17755	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CX039_RS17785	COG0697	spore germination
CX039_RS17800	COG3181	Tripartite tricarboxylate transporter family receptor
CX039_RS17825	COG0028	Belongs to the TPP enzyme family
CX039_RS17830	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX039_RS17835	COG1024	Enoyl-CoA hydratase
CX039_RS17835	COG1250	3-hydroxyacyl-CoA dehydrogenase
CX039_RS17840	COG3181	Tripartite tricarboxylate transporter family receptor
CX039_RS17850	COG0492	ferredoxin-NADP+ reductase activity
CX039_RS17870	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX039_RS17880	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX039_RS17900	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CX039_RS17915	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CX039_RS17920	COG2823	Periplasmic or secreted lipoprotein
CX039_RS17935	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CX039_RS17945	COG1309	transcriptional regulator
CX039_RS17950	COG0471	metal ion transport
CX039_RS17955	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CX039_RS17960	COG0772	Belongs to the SEDS family
CX039_RS17965	COG0768	penicillin binding
CX039_RS17975	COG1792	Involved in formation and maintenance of cell shape
CX039_RS17980	COG1077	Cell shape determining protein MreB Mrl
CX039_RS17985	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CX039_RS17990	COG0154	amidase activity
CX039_RS17995	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CX039_RS18000	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CX039_RS18005	COG0708	Exodeoxyribonuclease III
CX039_RS18010	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CX039_RS18015	COG2860	membrane
CX039_RS18050	COG1012	belongs to the aldehyde dehydrogenase family
CX039_RS18060	COG3069	C4-dicarboxylate transmembrane transporter activity
CX039_RS18070	COG1802	Transcriptional regulator
CX039_RS18105	COG1595	DNA-templated transcription, initiation
CX039_RS18110	COG3712	iron ion homeostasis
CX039_RS18120	COG3720	iron ion transport
CX039_RS18125	COG4558	Periplasmic binding protein
CX039_RS18130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CX039_RS18135	COG1120	ATPase activity
CX039_RS18140	COG1683	Conserved Protein
CX039_RS18170	COG3064	Membrane
CX039_RS18190	COG1234	tRNA 3'-trailer cleavage
CX039_RS18225	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CX039_RS18235	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CX039_RS18250	COG0540	Belongs to the ATCase OTCase family
CX039_RS18255	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CX039_RS18260	COG1678	Uncharacterized ACR, COG1678
CX039_RS18275	COG0352	thiamine-phosphate diphosphorylase activity
CX039_RS18280	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CX039_RS18305	COG1960	acyl-CoA dehydrogenase activity
CX039_RS18310	COG1024	Enoyl-CoA hydratase
CX039_RS18380	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
CX039_RS18390	COG0583	DNA-binding transcription factor activity
CX039_RS18395	COG2814	Major facilitator Superfamily
CX039_RS18400	COG0129	dihydroxy-acid dehydratase activity
CX039_RS18405	COG2207	Transcriptional regulator
CX039_RS18410	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CX039_RS18420	COG0657	acetylesterase activity
CX039_RS18425	COG0747	negative chemotaxis
CX039_RS18430	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CX039_RS18435	COG2808	Putative FMN-binding domain
CX039_RS18450	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CX039_RS18455	COG1970	mechanosensitive ion channel activity
CX039_RS18460	COG0723	plastoquinol--plastocyanin reductase activity
CX039_RS18465	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CX039_RS18470	COG2857	Cytochrome c1
CX039_RS18475	COG0625	glutathione transferase activity
CX039_RS18480	COG2969	positive regulation of protein catabolic process
CX039_RS18530	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CX039_RS18535	COG4988	ABC transporter
CX039_RS18545	COG1294	oxidase, subunit
CX039_RS18580	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX039_RS18585	COG0405	Gamma-glutamyltransferase
CX039_RS18595	COG3181	Tripartite tricarboxylate transporter family receptor
CX039_RS18605	COG0114	fumarate hydratase activity
CX039_RS18610	COG0802	atpase or kinase
CX039_RS18615	COG0860	N-Acetylmuramoyl-L-alanine amidase
CX039_RS18620	COG0586	Pfam SNARE associated Golgi protein
CX039_RS18625	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CX039_RS18630	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CX039_RS18635	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CX039_RS18650	COG0617	tRNA 3'-terminal CCA addition
CX039_RS18675	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CX039_RS18680	COG2188	Transcriptional regulator
CX039_RS18690	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CX039_RS18700	COG1028	Short-chain dehydrogenase reductase Sdr
CX039_RS18725	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CX039_RS18730	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CX039_RS18735	COG1012	belongs to the aldehyde dehydrogenase family
CX039_RS18760	COG4257	antibiotic catabolic process
CX039_RS18770	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CX039_RS18775	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CX039_RS18785	COG1250	3-hydroxyacyl-CoA dehydrogenase
CX039_RS18790	COG2031	fatty acid transporter
CX039_RS18795	COG1028	Short-chain dehydrogenase reductase Sdr
CX039_RS18800	COG1414	Transcriptional regulator
CX039_RS18810	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CX039_RS18825	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CX039_RS18865	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CX039_RS18865	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CX039_RS18870	COG0509	glycine decarboxylation via glycine cleavage system
CX039_RS18875	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CX039_RS18885	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CX039_RS18895	COG2081	HI0933 family
CX039_RS18925	COG0717	Belongs to the dCTP deaminase family
CX039_RS18940	COG0489	protein tyrosine kinase activity
CX039_RS18950	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CX039_RS18950	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CX039_RS18955	COG1054	Belongs to the UPF0176 family
CX039_RS18995	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CX039_RS19000	COG1280	lysine exporter protein (LysE YggA)
CX039_RS19005	COG0513	Belongs to the DEAD box helicase family
CX039_RS19015	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CX039_RS19035	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CX039_RS19050	COG2226	methyltransferase
CX039_RS19055	COG0745	RESPONSE REGULATOR receiver
CX039_RS19060	COG5002	protein histidine kinase activity
CX039_RS19070	COG5002	protein histidine kinase activity
CX039_RS19080	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CX039_RS19085	COG0583	DNA-binding transcription factor activity
CX039_RS19095	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CX039_RS19100	COG1984	allophanate hydrolase subunit 2
CX039_RS19115	COG3181	Tripartite tricarboxylate transporter family receptor
CX039_RS19130	COG1024	Enoyl-CoA hydratase
CX039_RS19145	COG1802	Transcriptional regulator
CX039_RS19160	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CX039_RS19180	COG0583	DNA-binding transcription factor activity
CX039_RS19190	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CX039_RS19200	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CX039_RS19205	COG0154	amidase activity
CX039_RS19215	COG1609	Transcriptional regulator
CX039_RS19235	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CX039_RS19255	COG2814	Major facilitator Superfamily
CX039_RS19260	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CX039_RS19280	COG1999	signal sequence binding
CX039_RS19285	COG0109	protoheme IX farnesyltransferase activity
CX039_RS19325	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CX039_RS19345	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CX039_RS19350	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CX039_RS19360	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CX039_RS19365	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CX039_RS19375	COG0070	glutamate synthase
CX039_RS19375	COG0067	glutamate synthase
CX039_RS19375	COG0069	glutamate synthase activity
CX039_RS19385	COG3047	cAMP biosynthetic process
CX039_RS19395	COG1127	ABC transporter
CX039_RS19400	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CX039_RS19405	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CX039_RS19410	COG2853	Lipoprotein
CX039_RS19425	COG0842	Transport permease protein
CX039_RS19435	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CX039_RS19440	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CX039_RS19445	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CX039_RS19450	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CX039_RS19455	COG0131	Imidazoleglycerol-phosphate dehydratase
CX039_RS19460	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CX039_RS19465	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CX039_RS19470	COG0107	imidazoleglycerol-phosphate synthase activity
CX039_RS19475	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CX039_RS19480	COG0140	phosphoribosyl-ATP diphosphatase activity
CX039_RS19485	COG0537	adenosine 5'-monophosphoramidase activity
CX039_RS19490	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CX039_RS19495	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CX039_RS19510	COG3181	Tripartite tricarboxylate transporter family receptor
CX039_RS19545	COG3702	type iv secretory pathway
CX039_RS19550	COG3451	type IV secretory pathway VirB4
CX039_RS19565	COG3736	Type IV secretory pathway, component VirB8
CX039_RS19570	COG3504	Conjugal transfer protein
CX039_RS19575	COG2948	multi-organism process
CX039_RS19580	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
CX039_RS19590	COG0697	spore germination
CX039_RS19610	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CX039_RS19615	COG0747	negative chemotaxis
CX039_RS19620	COG0601	transmembrane transport
CX039_RS19625	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CX039_RS19640	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CX039_RS19650	COG0494	nUDIX hydrolase
CX039_RS19695	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
CX039_RS19700	COG0237	dephospho-CoA kinase activity
CX039_RS19705	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CX039_RS19720	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CX039_RS19725	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CX039_RS19735	COG0477	Major facilitator Superfamily
CX039_RS19740	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CX039_RS19755	COG1126	abc transporter atp-binding protein
CX039_RS19760	COG0765	amino acid transport
CX039_RS19765	COG4597	amino acid ABC transporter
CX039_RS19770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CX039_RS19775	COG2884	Cell division ATP-binding protein ftsE
CX039_RS19780	COG2177	Part of the ABC transporter FtsEX involved in
CX039_RS19785	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CX039_RS19795	COG1194	a g-specific adenine glycosylase
CX039_RS19805	COG2226	methyltransferase
CX039_RS19815	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX039_RS19820	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX039_RS19835	COG1024	Enoyl-CoA hydratase
CX039_RS19855	COG1024	Enoyl-CoA hydratase
CX039_RS19860	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CX039_RS19875	COG0753	catalase activity
CX039_RS19880	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CX039_RS19885	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CX039_RS19895	COG2175	clavaminate synthase activity
CX039_RS19900	COG1473	amidohydrolase
CX039_RS19905	COG4608	Belongs to the ABC transporter superfamily
CX039_RS19910	COG0444	Belongs to the ABC transporter superfamily
CX039_RS19925	COG0747	negative chemotaxis
CX039_RS19930	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CX039_RS19965	COG0436	Aminotransferase
CX039_RS19970	COG1278	Cold shock