locus-tag	class	description
CG027_RS00005	COG0445	tRNA wobble uridine modification
CG027_RS00010	COG0357	Ribosomal RNA small subunit methyltransferase G
CG027_RS00015	COG1192	Involved in chromosome partitioning
CG027_RS00025	COG1475	DNA binding
CG027_RS00050	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CG027_RS00060	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CG027_RS00070	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CG027_RS00075	COG0081	regulation of translation
CG027_RS00080	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CG027_RS00085	COG0222	ribosome binding
CG027_RS00090	COG0085	RNA polymerase activity
CG027_RS00095	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CG027_RS00135	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CG027_RS00160	COG1024	Enoyl-CoA hydratase
CG027_RS00180	COG0752	glycyl-tRNA synthetase alpha subunit
CG027_RS00185	COG0751	glycine-tRNA ligase activity
CG027_RS00190	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CG027_RS00195	COG0204	Acyl-transferase
CG027_RS00210	COG0242	peptide deformylase activity
CG027_RS00250	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CG027_RS00255	COG2813	Specifically methylates the guanine in position
CG027_RS00255	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CG027_RS00270	COG2223	nitrite transmembrane transporter activity
CG027_RS00280	COG1794	racemase activity, acting on amino acids and derivatives
CG027_RS00285	COG1126	abc transporter atp-binding protein
CG027_RS00290	COG0765	amino acid transport
CG027_RS00295	COG0765	amino acid transport
CG027_RS00300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG027_RS00365	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CG027_RS00395	COG0326	Molecular chaperone. Has ATPase activity
CG027_RS00400	COG0625	glutathione transferase activity
CG027_RS00415	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CG027_RS00420	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CG027_RS00450	COG0438	transferase activity, transferring glycosyl groups
CG027_RS00455	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CG027_RS00460	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CG027_RS00490	COG0859	PFAM glycosyl transferase family 9
CG027_RS00505	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CG027_RS00515	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CG027_RS00520	COG1127	ABC transporter
CG027_RS00540	COG1686	Belongs to the peptidase S11 family
CG027_RS00550	COG2921	Belongs to the UPF0250 family
CG027_RS00555	COG0321	lipoyl(octanoyl) transferase activity
CG027_RS00560	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CG027_RS00595	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CG027_RS00605	COG0018	arginyl-trna synthetase
CG027_RS00625	COG0395	ABC-type sugar transport system, permease component
CG027_RS00630	COG1175	transmembrane transport
CG027_RS00635	COG1653	transport
CG027_RS00640	COG3842	ATPase activity
CG027_RS00645	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CG027_RS00655	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CG027_RS00675	COG1609	Transcriptional regulator
CG027_RS00685	COG0154	amidase activity
CG027_RS00690	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CG027_RS00700	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CG027_RS00710	COG0583	DNA-binding transcription factor activity
CG027_RS00730	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CG027_RS00745	COG1802	Transcriptional regulator
CG027_RS00760	COG1024	Enoyl-CoA hydratase
CG027_RS00770	COG3181	Tripartite tricarboxylate transporter family receptor
CG027_RS00785	COG1984	allophanate hydrolase subunit 2
CG027_RS00790	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CG027_RS00800	COG0583	DNA-binding transcription factor activity
CG027_RS00805	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CG027_RS00815	COG5002	protein histidine kinase activity
CG027_RS00825	COG5002	protein histidine kinase activity
CG027_RS00830	COG0745	RESPONSE REGULATOR receiver
CG027_RS00835	COG2226	methyltransferase
CG027_RS00850	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CG027_RS00870	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CG027_RS00880	COG0513	Belongs to the DEAD box helicase family
CG027_RS00885	COG1280	lysine exporter protein (LysE YggA)
CG027_RS00890	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CG027_RS00930	COG1054	Belongs to the UPF0176 family
CG027_RS00935	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CG027_RS00935	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CG027_RS00945	COG0489	protein tyrosine kinase activity
CG027_RS00960	COG0717	Belongs to the dCTP deaminase family
CG027_RS00990	COG2081	HI0933 family
CG027_RS01000	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CG027_RS01010	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CG027_RS01015	COG0509	glycine decarboxylation via glycine cleavage system
CG027_RS01020	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CG027_RS01020	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CG027_RS01060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CG027_RS01075	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CG027_RS01085	COG1414	Transcriptional regulator
CG027_RS01090	COG1028	Short-chain dehydrogenase reductase Sdr
CG027_RS01095	COG2031	fatty acid transporter
CG027_RS01100	COG1250	3-hydroxyacyl-CoA dehydrogenase
CG027_RS01110	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CG027_RS01115	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CG027_RS01125	COG4257	antibiotic catabolic process
CG027_RS01150	COG1012	belongs to the aldehyde dehydrogenase family
CG027_RS01155	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CG027_RS01160	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CG027_RS01185	COG1028	Short-chain dehydrogenase reductase Sdr
CG027_RS01195	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CG027_RS01205	COG2188	Transcriptional regulator
CG027_RS01210	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CG027_RS01235	COG0617	tRNA 3'-terminal CCA addition
CG027_RS01250	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CG027_RS01255	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CG027_RS01260	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CG027_RS01265	COG0586	Pfam SNARE associated Golgi protein
CG027_RS01270	COG0860	N-Acetylmuramoyl-L-alanine amidase
CG027_RS01275	COG0802	atpase or kinase
CG027_RS01280	COG0114	fumarate hydratase activity
CG027_RS01290	COG3181	Tripartite tricarboxylate transporter family receptor
CG027_RS01300	COG0405	Gamma-glutamyltransferase
CG027_RS01305	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CG027_RS01340	COG1294	oxidase, subunit
CG027_RS01350	COG4988	ABC transporter
CG027_RS01355	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CG027_RS01405	COG2969	positive regulation of protein catabolic process
CG027_RS01410	COG0625	glutathione transferase activity
CG027_RS01415	COG2857	Cytochrome c1
CG027_RS01420	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CG027_RS01425	COG0723	plastoquinol--plastocyanin reductase activity
CG027_RS01430	COG1970	mechanosensitive ion channel activity
CG027_RS01435	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CG027_RS01450	COG2808	Putative FMN-binding domain
CG027_RS01455	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CG027_RS01460	COG0747	negative chemotaxis
CG027_RS01465	COG0657	acetylesterase activity
CG027_RS01475	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CG027_RS01480	COG2207	Transcriptional regulator
CG027_RS01485	COG0129	dihydroxy-acid dehydratase activity
CG027_RS01490	COG2814	Major facilitator Superfamily
CG027_RS01495	COG0583	DNA-binding transcription factor activity
CG027_RS01505	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
CG027_RS01575	COG1024	Enoyl-CoA hydratase
CG027_RS01580	COG1960	acyl-CoA dehydrogenase activity
CG027_RS01605	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CG027_RS01610	COG0352	thiamine-phosphate diphosphorylase activity
CG027_RS01625	COG1678	Uncharacterized ACR, COG1678
CG027_RS01630	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CG027_RS01635	COG0540	Belongs to the ATCase OTCase family
CG027_RS01650	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CG027_RS01660	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CG027_RS01695	COG1234	tRNA 3'-trailer cleavage
CG027_RS01715	COG3064	Membrane
CG027_RS01745	COG1683	Conserved Protein
CG027_RS01750	COG1120	ATPase activity
CG027_RS01755	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CG027_RS01760	COG4558	Periplasmic binding protein
CG027_RS01765	COG3720	iron ion transport
CG027_RS01775	COG3712	iron ion homeostasis
CG027_RS01780	COG1595	DNA-templated transcription, initiation
CG027_RS01815	COG1802	Transcriptional regulator
CG027_RS01825	COG3069	C4-dicarboxylate transmembrane transporter activity
CG027_RS01835	COG1012	belongs to the aldehyde dehydrogenase family
CG027_RS01870	COG2860	membrane
CG027_RS01875	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CG027_RS01880	COG0708	Exodeoxyribonuclease III
CG027_RS01885	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CG027_RS01890	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CG027_RS01895	COG0154	amidase activity
CG027_RS01900	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CG027_RS01905	COG1077	Cell shape determining protein MreB Mrl
CG027_RS01910	COG1792	Involved in formation and maintenance of cell shape
CG027_RS01920	COG0768	penicillin binding
CG027_RS01925	COG0772	Belongs to the SEDS family
CG027_RS01930	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CG027_RS01935	COG0471	metal ion transport
CG027_RS01940	COG1309	transcriptional regulator
CG027_RS01950	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CG027_RS01965	COG2823	Periplasmic or secreted lipoprotein
CG027_RS01970	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CG027_RS01985	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CG027_RS02005	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CG027_RS02015	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CG027_RS02035	COG0492	ferredoxin-NADP+ reductase activity
CG027_RS02045	COG3181	Tripartite tricarboxylate transporter family receptor
CG027_RS02050	COG1024	Enoyl-CoA hydratase
CG027_RS02050	COG1250	3-hydroxyacyl-CoA dehydrogenase
CG027_RS02055	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CG027_RS02060	COG0028	Belongs to the TPP enzyme family
CG027_RS02085	COG3181	Tripartite tricarboxylate transporter family receptor
CG027_RS02100	COG0697	spore germination
CG027_RS02130	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CG027_RS02135	COG0463	Glycosyl transferase, family 2
CG027_RS02150	COG0786	glutamate:sodium symporter activity
CG027_RS02160	COG2031	fatty acid transporter
CG027_RS02175	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CG027_RS02190	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CG027_RS02205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CG027_RS02215	COG1285	pathogenesis
CG027_RS02220	COG1253	flavin adenine dinucleotide binding
CG027_RS02225	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CG027_RS02230	COG1024	Enoyl-CoA hydratase
CG027_RS02235	COG3181	Tripartite tricarboxylate transporter family receptor
CG027_RS02240	COG0583	DNA-binding transcription factor activity
CG027_RS02245	COG1960	acyl-CoA dehydrogenase activity
CG027_RS02255	COG0183	Belongs to the thiolase family
CG027_RS02275	COG0583	DNA-binding transcription factor activity
CG027_RS02280	COG1278	Cold shock
CG027_RS02290	COG1802	Transcriptional regulator
CG027_RS02295	COG1012	belongs to the aldehyde dehydrogenase family
CG027_RS02300	COG2031	fatty acid transporter
CG027_RS02305	COG1017	nitric oxide dioxygenase activity
CG027_RS02305	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CG027_RS02310	COG0251	oxidation-reduction process
CG027_RS02330	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CG027_RS02340	COG0583	DNA-binding transcription factor activity
CG027_RS02345	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CG027_RS02365	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CG027_RS02370	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CG027_RS02375	COG0546	phosphoglycolate phosphatase activity
CG027_RS02385	COG1530	ribonuclease E activity
CG027_RS02405	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CG027_RS02410	COG0159	tryptophan synthase activity
CG027_RS02415	COG0133	tryptophan synthase activity
CG027_RS02425	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CG027_RS02430	COG3228	Belongs to the MtfA family
CG027_RS02440	COG0251	oxidation-reduction process
CG027_RS02445	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CG027_RS02450	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CG027_RS02465	COG2878	Part of a membrane complex involved in electron transport
CG027_RS02470	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CG027_RS02505	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CG027_RS02525	COG1268	BioY protein
CG027_RS02530	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CG027_RS02535	COG1122	ATPase activity
CG027_RS02540	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CG027_RS02555	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CG027_RS02560	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CG027_RS02570	COG1196	nuclear chromosome segregation
CG027_RS02575	COG0477	Major facilitator Superfamily
CG027_RS02580	COG1573	uracil-dna glycosylase
CG027_RS02585	COG1214	PFAM Peptidase M22, glycoprotease
CG027_RS02605	COG0450	alkyl hydroperoxide reductase
CG027_RS02610	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CG027_RS02620	COG2223	nitrite transmembrane transporter activity
CG027_RS02630	COG2186	Transcriptional regulator
CG027_RS02650	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CG027_RS02660	COG0583	DNA-binding transcription factor activity
CG027_RS02670	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CG027_RS02675	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CG027_RS02680	COG0137	argininosuccinate synthase activity
CG027_RS02685	COG3158	transport of potassium into the cell
CG027_RS02690	COG0642	Histidine kinase
CG027_RS02720	COG0776	regulation of translation
CG027_RS02725	COG3128	pkhd-type hydroxylase
CG027_RS02735	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CG027_RS02740	COG0557	exoribonuclease II activity
CG027_RS02765	COG0679	Auxin Efflux Carrier
CG027_RS02770	COG2391	methyltransferase activity
CG027_RS02775	COG0069	glutamate synthase activity
CG027_RS02790	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CG027_RS02800	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
CG027_RS02840	COG3706	GGDEF domain
CG027_RS02860	COG1053	succinate dehydrogenase
CG027_RS02865	COG0583	DNA-binding transcription factor activity
CG027_RS02880	COG1053	succinate dehydrogenase
CG027_RS02900	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CG027_RS02905	COG0459	protein refolding
CG027_RS02910	COG3468	outer membrane autotransporter barrel domain protein
CG027_RS02925	COG1252	NADH dehydrogenase
CG027_RS02930	COG0284	orotidine-5'-phosphate decarboxylase activity
CG027_RS02935	COG1546	Belongs to the CinA family
CG027_RS02935	COG1058	Belongs to the CinA family
CG027_RS02940	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CG027_RS02950	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CG027_RS02955	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CG027_RS02995	COG3639	organic phosphonate transmembrane transporter activity
CG027_RS03000	COG3639	organic phosphonate transmembrane transporter activity
CG027_RS03020	COG0742	ribosomal rna small subunit methyltransferase
CG027_RS03025	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CG027_RS03030	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CG027_RS03035	COG3135	benzoate transporter
CG027_RS03050	COG0640	Transcriptional regulator
CG027_RS03080	COG4172	Belongs to the ABC transporter superfamily
CG027_RS03085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CG027_RS03090	COG0601	transmembrane transport
CG027_RS03100	COG0281	malic enzyme
CG027_RS03100	COG0280	phosphate acetyltransferase
CG027_RS03160	COG0583	DNA-binding transcription factor activity
CG027_RS03175	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CG027_RS03180	COG0167	dihydroorotate dehydrogenase activity
CG027_RS03200	COG1414	Transcriptional regulator
CG027_RS03205	COG1058	Belongs to the CinA family
CG027_RS03205	COG1546	Belongs to the CinA family
CG027_RS03225	COG0513	Belongs to the DEAD box helicase family
CG027_RS03255	COG0429	hydrolase of the alpha beta-hydrolase fold
CG027_RS03260	COG4783	chaperone-mediated protein folding
CG027_RS03275	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CG027_RS03300	COG0006	proline dipeptidase activity
CG027_RS03310	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CG027_RS03330	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CG027_RS03335	COG0632	four-way junction helicase activity
CG027_RS03350	COG2255	four-way junction helicase activity
CG027_RS03355	COG0514	ATP-dependent DNA helicase (RecQ)
CG027_RS03370	COG0288	reversible hydration of carbon dioxide
CG027_RS03375	COG0154	amidase activity
CG027_RS03385	COG4211	Belongs to the binding-protein-dependent transport system permease family
CG027_RS03415	COG1464	Belongs to the NlpA lipoprotein family
CG027_RS03555	COG1196	nuclear chromosome segregation
CG027_RS03630	COG2135	peptidase activity
CG027_RS03645	COG0494	nUDIX hydrolase
CG027_RS03650	COG0442	prolyl-tRNA aminoacylation
CG027_RS03655	COG0824	Thioesterase
CG027_RS03660	COG0811	peptide transport
CG027_RS03665	COG0848	biopolymer transport protein
CG027_RS03675	COG0823	Involved in the tonB-independent uptake of proteins
CG027_RS03690	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CG027_RS03695	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CG027_RS03730	COG0700	Nucleoside recognition
CG027_RS03735	COG0469	pyruvate kinase activity
CG027_RS03740	COG1929	Belongs to the glycerate kinase type-1 family
CG027_RS03745	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CG027_RS03750	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CG027_RS03755	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CG027_RS03765	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CG027_RS03775	COG2154	pterin-4-alpha-carbinolamine dehydratase
CG027_RS03800	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CG027_RS03805	COG0154	amidase activity
CG027_RS03815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CG027_RS03820	COG0601	transmembrane transport
CG027_RS03825	COG0747	negative chemotaxis
CG027_RS03845	COG0019	diaminopimelate decarboxylase activity
CG027_RS03860	COG2353	YceI-like domain
CG027_RS03865	COG4774	siderophore transport
CG027_RS03870	COG3712	iron ion homeostasis
CG027_RS03915	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CG027_RS03920	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CG027_RS03925	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CG027_RS03930	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CG027_RS03940	COG0142	geranyltranstransferase activity
CG027_RS03950	COG0583	DNA-binding transcription factor activity
CG027_RS03960	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
CG027_RS03965	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CG027_RS03985	COG2994	toxin metabolic process
CG027_RS03995	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CG027_RS04000	COG2274	protein secretion by the type I secretion system
CG027_RS04005	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CG027_RS04010	COG1538	Outer membrane efflux protein
CG027_RS04030	COG0765	amino acid transport
CG027_RS04035	COG1126	abc transporter atp-binding protein
CG027_RS04055	COG1028	Short-chain dehydrogenase reductase Sdr
CG027_RS04065	COG1802	Transcriptional regulator
CG027_RS04075	COG1802	Transcriptional regulator
CG027_RS04085	COG0318	PFAM AMP-dependent synthetase and ligase
CG027_RS04095	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CG027_RS04115	COG0028	Belongs to the TPP enzyme family
CG027_RS04135	COG0308	aminopeptidase N
CG027_RS04140	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CG027_RS04155	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CG027_RS04160	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CG027_RS04165	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CG027_RS04170	COG0560	Phosphoserine phosphatase
CG027_RS04175	COG0583	DNA-binding transcription factor activity
CG027_RS04180	COG3181	Tripartite tricarboxylate transporter family receptor
CG027_RS04185	COG0028	Belongs to the TPP enzyme family
CG027_RS04200	COG4774	siderophore transport
CG027_RS04205	COG4774	siderophore transport
CG027_RS04215	COG1007	ATP synthesis coupled electron transport
CG027_RS04230	COG0713	ATP synthesis coupled electron transport
CG027_RS04240	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CG027_RS04245	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CG027_RS04250	COG1034	ATP synthesis coupled electron transport
CG027_RS04260	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CG027_RS04265	COG0649	NAD binding
CG027_RS04270	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CG027_RS04275	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CG027_RS04280	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CG027_RS04285	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CG027_RS04315	COG0671	phosphoesterase, PA-phosphatase related
CG027_RS04325	COG1597	lipid kinase activity
CG027_RS04330	COG0583	DNA-binding transcription factor activity
CG027_RS04335	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CG027_RS04345	COG1733	regulation of RNA biosynthetic process
CG027_RS04350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CG027_RS04355	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CG027_RS04370	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
CG027_RS04390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CG027_RS04410	COG3608	succinylglutamate desuccinylase aspartoacylase
CG027_RS04415	COG0626	cystathionine gamma-synthase activity
CG027_RS04420	COG0583	DNA-binding transcription factor activity
CG027_RS04455	COG3799	methylaspartate ammonia-lyase activity
CG027_RS04465	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CG027_RS04475	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CG027_RS04480	COG0149	triose-phosphate isomerase activity
CG027_RS04500	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CG027_RS04515	COG1185	polyribonucleotide nucleotidyltransferase activity
CG027_RS04520	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CG027_RS04535	COG1183	phosphatidylcholine synthase activity
CG027_RS04540	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CG027_RS04545	COG0440	acetolactate synthase activity
CG027_RS04550	COG0028	Belongs to the TPP enzyme family
CG027_RS04565	COG5265	(ABC) transporter
CG027_RS04570	COG0500	methyltransferase
CG027_RS04590	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CG027_RS04610	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CG027_RS04620	COG0511	ligase activity, forming carbon-carbon bonds
CG027_RS04645	COG2188	Transcriptional regulator
CG027_RS04650	COG0439	Biotin carboxylase
CG027_RS04700	COG5265	(ABC) transporter
CG027_RS04710	COG0667	Aldo Keto reductase
CG027_RS04725	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CG027_RS04765	COG0583	DNA-binding transcription factor activity
CG027_RS04800	COG2814	Major facilitator Superfamily
CG027_RS04810	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CG027_RS04825	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CG027_RS04835	COG0287	Prephenate dehydrogenase
CG027_RS04840	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CG027_RS04845	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CG027_RS04865	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CG027_RS04870	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CG027_RS04875	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CG027_RS04880	COG1555	photosystem II stabilization
CG027_RS04880	COG1596	polysaccharide export
CG027_RS04895	COG2951	lytic endotransglycosylase activity
CG027_RS04900	COG0123	including yeast histone deacetylase and acetoin utilization protein
CG027_RS04915	COG1960	acyl-CoA dehydrogenase activity
CG027_RS04920	COG0450	alkyl hydroperoxide reductase
CG027_RS04940	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CG027_RS04975	COG0335	large ribosomal subunit rRNA binding
CG027_RS04990	COG0667	Aldo Keto reductase
CG027_RS05005	COG3161	chorismate lyase activity
CG027_RS05010	COG1187	pseudouridine synthase activity
CG027_RS05040	COG1999	signal sequence binding
CG027_RS05045	COG0339	signal peptide processing
CG027_RS05050	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CG027_RS05055	COG4566	intracellular signal transduction
CG027_RS05065	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CG027_RS05070	COG0508	dehydrogenase complex catalyzes the overall conversion of
CG027_RS05075	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CG027_RS05080	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CG027_RS05090	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CG027_RS05095	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CG027_RS05100	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CG027_RS05105	COG0126	phosphoglycerate kinase activity
CG027_RS05110	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CG027_RS05115	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CG027_RS05130	COG0625	glutathione transferase activity
CG027_RS05160	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CG027_RS05170	COG0521	Mo-molybdopterin cofactor biosynthetic process
CG027_RS05180	COG0739	heme binding
CG027_RS05190	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CG027_RS05225	COG0745	RESPONSE REGULATOR receiver
CG027_RS05240	COG0840	transmembrane signaling receptor activity
CG027_RS05250	COG2201	protein-glutamate methylesterase activity
CG027_RS05255	COG0745	RESPONSE REGULATOR receiver
CG027_RS05260	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CG027_RS05285	COG0667	Aldo Keto reductase
CG027_RS05295	COG4535	Mg2 and Co2 transporter CorC
CG027_RS05300	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CG027_RS05305	COG1702	phosphate starvation-inducible protein PhoH
CG027_RS05310	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CG027_RS05325	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CG027_RS05330	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CG027_RS05335	COG1862	Preprotein translocase
CG027_RS05340	COG0343	queuine tRNA-ribosyltransferase activity
CG027_RS05345	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CG027_RS05350	COG2027	D-alanyl-D-alanine carboxypeptidase
CG027_RS05355	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CG027_RS05385	COG1648	precorrin-2 dehydrogenase activity
CG027_RS05385	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CG027_RS05410	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CG027_RS05415	COG0741	lytic transglycosylase activity
CG027_RS05425	COG0436	Aminotransferase
CG027_RS05435	COG0281	malic enzyme
CG027_RS05435	COG0280	phosphate acetyltransferase
CG027_RS05445	COG2732	(Barnase) inhibitor
CG027_RS05460	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CG027_RS05485	COG0248	Ppx GppA phosphatase
CG027_RS05495	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CG027_RS05505	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CG027_RS05510	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CG027_RS05515	COG1534	Rna-binding protein
CG027_RS05545	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CG027_RS05560	COG1295	ribonuclease BN
CG027_RS05570	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CG027_RS05575	COG0745	RESPONSE REGULATOR receiver
CG027_RS05580	COG2205	protein histidine kinase activity
CG027_RS05615	COG1022	Amp-dependent synthetase and ligase
CG027_RS05630	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CG027_RS05635	COG1028	Short-chain dehydrogenase reductase Sdr
CG027_RS05645	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CG027_RS05660	COG1136	(ABC) transporter
CG027_RS05665	COG0084	hydrolase, TatD family'
CG027_RS05690	COG0658	competence protein
CG027_RS05690	COG2333	competence protein COMEC
CG027_RS05700	COG0613	PHP domain protein
CG027_RS05720	COG3539	Fimbrial protein
CG027_RS05725	COG0281	malic enzyme
CG027_RS05725	COG0280	phosphate acetyltransferase
CG027_RS05735	COG1522	sequence-specific DNA binding
CG027_RS05745	COG0567	Dehydrogenase, E1 component
CG027_RS05750	COG0508	dehydrogenase complex catalyzes the overall conversion of
CG027_RS05755	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CG027_RS05760	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CG027_RS05765	COG1028	Short-chain dehydrogenase reductase Sdr
CG027_RS05770	COG0583	DNA-binding transcription factor activity
CG027_RS05780	COG3181	Tripartite tricarboxylate transporter family receptor
CG027_RS05805	COG0180	Tryptophanyl-tRNA synthetase
CG027_RS05810	COG2183	response to ionizing radiation
CG027_RS05815	COG1199	ATP-dependent helicase activity
CG027_RS05825	COG0564	pseudouridine synthase activity
CG027_RS05835	COG3243	poly(R)-hydroxyalkanoic acid synthase
CG027_RS05840	COG1028	Short-chain dehydrogenase reductase Sdr
CG027_RS05845	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
CG027_RS05860	COG0672	)-iron permease
CG027_RS05900	COG0583	DNA-binding transcription factor activity
CG027_RS05910	COG2814	Major facilitator Superfamily
CG027_RS05925	COG1619	proteins homologs of microcin C7 resistance protein MccF
CG027_RS05940	COG2084	Dehydrogenase
CG027_RS05945	COG3181	Tripartite tricarboxylate transporter family receptor
CG027_RS05970	COG2988	succinylglutamate desuccinylase activity
CG027_RS06000	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CG027_RS06005	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CG027_RS06005	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CG027_RS06010	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CG027_RS06015	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CG027_RS06015	COG0047	phosphoribosylformylglycinamidine synthase activity
CG027_RS06020	COG3210	domain, Protein
CG027_RS06020	COG3064	Membrane
CG027_RS06020	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CG027_RS06050	COG0235	Class ii aldolase
CG027_RS06055	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CG027_RS06060	COG0720	synthase
CG027_RS06065	COG0602	queuosine metabolic process
CG027_RS06090	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CG027_RS06125	COG3181	Tripartite tricarboxylate transporter family receptor
CG027_RS06150	COG3842	ATPase activity
CG027_RS06160	COG0395	ABC-type sugar transport system, permease component
CG027_RS06190	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CG027_RS06195	COG0420	3'-5' exonuclease activity
CG027_RS06240	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CG027_RS06240	COG0519	Catalyzes the synthesis of GMP from XMP
CG027_RS06255	COG3550	peptidyl-serine autophosphorylation
CG027_RS06265	COG0477	Major facilitator Superfamily
CG027_RS06280	COG1228	amidohydrolase
CG027_RS06290	COG1116	anion transmembrane transporter activity
CG027_RS06295	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CG027_RS06330	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CG027_RS06350	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CG027_RS06380	COG2814	Major facilitator Superfamily
CG027_RS06395	COG1280	lysine exporter protein (LysE YggA)
CG027_RS06410	COG0747	negative chemotaxis
CG027_RS06415	COG0601	transmembrane transport
CG027_RS06420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CG027_RS06425	COG4172	Belongs to the ABC transporter superfamily
CG027_RS06430	COG1609	Transcriptional regulator
CG027_RS06460	COG0586	Pfam SNARE associated Golgi protein
CG027_RS06475	COG0500	methyltransferase
CG027_RS06490	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CG027_RS06500	COG0756	dUTP diphosphatase activity
CG027_RS06510	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CG027_RS06515	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CG027_RS06520	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CG027_RS06525	COG0072	phenylalanine-tRNA ligase activity
CG027_RS06525	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CG027_RS06530	COG0776	regulation of translation
CG027_RS06595	COG0540	Belongs to the ATCase OTCase family
CG027_RS06600	COG2974	May be involved in recombination
CG027_RS06610	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CG027_RS06615	COG0583	DNA-binding transcription factor activity
CG027_RS06635	COG1028	Short-chain dehydrogenase reductase Sdr
CG027_RS06650	COG3842	ATPase activity
CG027_RS06655	COG1024	Enoyl-CoA hydratase
CG027_RS06655	COG1250	3-hydroxyacyl-CoA dehydrogenase
CG027_RS06675	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CG027_RS06680	COG2137	regulation of response to DNA damage stimulus
CG027_RS06690	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CG027_RS06700	COG0045	succinate-CoA ligase (ADP-forming) activity
CG027_RS06705	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CG027_RS06710	COG0861	Integral membrane protein TerC family
CG027_RS06715	COG0861	Integral membrane protein TerC family
CG027_RS06720	COG0181	hydroxymethylbilane synthase activity
CG027_RS06780	COG4964	Belongs to the GSP D family
CG027_RS06805	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CG027_RS06815	COG0583	DNA-binding transcription factor activity
CG027_RS06825	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CG027_RS06830	COG4311	Sarcosine oxidase, delta subunit
CG027_RS06835	COG0446	pyridine nucleotide-disulphide oxidoreductase
CG027_RS06835	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CG027_RS06870	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CG027_RS06875	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CG027_RS06880	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CG027_RS06885	COG0735	belongs to the Fur family
CG027_RS06890	COG0497	DNA recombination
CG027_RS06895	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CG027_RS06900	COG1420	regulation of RNA biosynthetic process
CG027_RS06905	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CG027_RS06915	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CG027_RS06925	COG0443	Heat shock 70 kDa protein
CG027_RS06935	COG0612	Peptidase, M16
CG027_RS06955	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CG027_RS07000	COG0745	RESPONSE REGULATOR receiver
CG027_RS07010	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CG027_RS07015	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CG027_RS07020	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CG027_RS07035	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CG027_RS07055	COG1193	negative regulation of DNA recombination
CG027_RS07060	COG0492	ferredoxin-NADP+ reductase activity
CG027_RS07065	COG1674	ftsk spoiiie
CG027_RS07070	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CG027_RS07075	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CG027_RS07080	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CG027_RS07105	COG3706	GGDEF domain
CG027_RS07125	COG2814	Major facilitator Superfamily
CG027_RS07155	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CG027_RS07170	COG1028	Short-chain dehydrogenase reductase Sdr
CG027_RS07180	COG3022	response to hydroperoxide
CG027_RS07220	COG2197	response regulator
CG027_RS07225	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CG027_RS07230	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CG027_RS07235	COG0189	ligase activity
CG027_RS07245	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CG027_RS07250	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CG027_RS07265	COG2423	ornithine cyclodeaminase activity
CG027_RS07275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG027_RS07280	COG0765	amino acid transport
CG027_RS07285	COG0765	amino acid transport
CG027_RS07290	COG1126	abc transporter atp-binding protein
CG027_RS07345	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CG027_RS07355	COG2944	sequence-specific DNA binding
CG027_RS07365	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CG027_RS07370	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CG027_RS07375	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CG027_RS07380	COG0009	L-threonylcarbamoyladenylate synthase
CG027_RS07385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG027_RS07390	COG1414	Transcriptional regulator
CG027_RS07405	COG0765	amino acid transport
CG027_RS07410	COG1126	abc transporter atp-binding protein
CG027_RS07415	COG0028	Belongs to the TPP enzyme family
CG027_RS07430	COG0028	Belongs to the TPP enzyme family
CG027_RS07435	COG0583	DNA-binding transcription factor activity
CG027_RS07440	COG4974	Belongs to the 'phage' integrase family
CG027_RS07445	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CG027_RS07450	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CG027_RS07465	COG1686	Belongs to the peptidase S11 family
CG027_RS07475	COG2814	Major facilitator Superfamily
CG027_RS07485	COG1074	ATP-dependent DNA helicase activity
CG027_RS07495	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CG027_RS07500	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CG027_RS07505	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CG027_RS07525	COG2321	neutral zinc metallopeptidase
CG027_RS07530	COG0009	L-threonylcarbamoyladenylate synthase
CG027_RS07575	COG3360	Dodecin
CG027_RS07580	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CG027_RS07585	COG2850	peptidyl-arginine hydroxylation
CG027_RS07590	COG3539	Fimbrial protein
CG027_RS07595	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CG027_RS07600	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CG027_RS07615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG027_RS07620	COG0765	amino acid transport
CG027_RS07625	COG1126	abc transporter atp-binding protein
CG027_RS07630	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CG027_RS07635	COG1758	RNA polymerase activity
CG027_RS07640	COG0194	GDP metabolic process
CG027_RS07645	COG3258	Cytochrome c
CG027_RS07650	COG2863	cytochrome
CG027_RS07655	COG1028	Short-chain dehydrogenase reductase Sdr
CG027_RS07660	COG0791	NLP P60 protein
CG027_RS07665	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CG027_RS07685	COG1561	YicC-like family, N-terminal region
CG027_RS07690	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CG027_RS07710	COG2200	EAL domain
CG027_RS07710	COG2199	diguanylate cyclase activity
CG027_RS07715	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CG027_RS07725	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CG027_RS07730	COG0174	glutamine synthetase
CG027_RS07740	COG2204	response regulator
CG027_RS07745	COG0583	DNA-binding transcription factor activity
CG027_RS07750	COG1741	Belongs to the pirin family
CG027_RS07755	COG1741	Belongs to the pirin family
CG027_RS07765	COG3842	ATPase activity
CG027_RS07770	COG1178	ABC-type Fe3 transport system permease component
CG027_RS07775	COG1840	ABC-type Fe3 transport system, periplasmic component
CG027_RS07785	COG0583	DNA-binding transcription factor activity
CG027_RS07795	COG0656	L-ascorbic acid biosynthetic process
CG027_RS07810	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CG027_RS07815	COG0583	DNA-binding transcription factor activity
CG027_RS07830	COG0783	Belongs to the Dps family
CG027_RS07850	COG0463	Glycosyl transferase, family 2
CG027_RS07870	COG0438	transferase activity, transferring glycosyl groups
CG027_RS07885	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CG027_RS07910	COG0300	oxidoreductase activity
CG027_RS07955	COG0861	Integral membrane protein TerC family
CG027_RS07960	COG1028	Short-chain dehydrogenase reductase Sdr
CG027_RS07980	COG0714	Associated with various cellular activities
CG027_RS08015	COG3119	arylsulfatase activity
CG027_RS08040	COG2197	response regulator
CG027_RS08050	COG2944	sequence-specific DNA binding
CG027_RS08060	COG0625	glutathione transferase activity
CG027_RS08090	COG0179	Fumarylacetoacetate (FAA) hydrolase
CG027_RS08095	COG1028	Short-chain dehydrogenase reductase Sdr
CG027_RS08140	COG0431	NADPH-dependent FMN reductase
CG027_RS08170	COG1028	Short-chain dehydrogenase reductase Sdr
CG027_RS08175	COG0583	DNA-binding transcription factor activity
CG027_RS08195	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CG027_RS08195	COG2111	Na H antiporter
CG027_RS08200	COG1006	Multisubunit Na H antiporter MnhC subunit
CG027_RS08205	COG0651	ATP synthesis coupled electron transport
CG027_RS08210	COG1863	multisubunit Na H antiporter MnhE subunit
CG027_RS08215	COG2212	antiporter activity
CG027_RS08240	COG0590	tRNA wobble adenosine to inosine editing
CG027_RS08245	COG1619	proteins homologs of microcin C7 resistance protein MccF
CG027_RS08250	COG1024	Enoyl-CoA hydratase
CG027_RS08265	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CG027_RS08270	COG0488	(ABC) transporter
CG027_RS08305	COG1017	nitric oxide dioxygenase activity
CG027_RS08305	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CG027_RS08310	COG1959	2 iron, 2 sulfur cluster binding
CG027_RS08315	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CG027_RS08335	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CG027_RS08340	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CG027_RS08345	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CG027_RS08350	COG0084	hydrolase, TatD family'
CG027_RS08365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG027_RS08375	COG1126	abc transporter atp-binding protein
CG027_RS08385	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CG027_RS08400	COG0028	Belongs to the TPP enzyme family
CG027_RS08410	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CG027_RS08410	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CG027_RS08420	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CG027_RS08470	COG4336	lyase activity
CG027_RS08480	COG2205	protein histidine kinase activity
CG027_RS08480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG027_RS08485	COG2197	response regulator
CG027_RS08490	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CG027_RS08490	COG3210	domain, Protein
CG027_RS08490	COG3064	Membrane
CG027_RS08500	COG3121	Chaperone
CG027_RS08505	COG3188	usher protein
CG027_RS08510	COG3539	Fimbrial protein
CG027_RS08515	COG2831	hemolysin activation secretion protein
CG027_RS08530	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CG027_RS08580	COG0668	transmembrane transport
CG027_RS08600	COG0483	inositol monophosphate 1-phosphatase activity
CG027_RS08605	COG1253	flavin adenine dinucleotide binding
CG027_RS08610	COG1968	undecaprenyl-diphosphatase activity
CG027_RS08615	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CG027_RS08630	COG0215	cysteine-tRNA ligase activity
CG027_RS08640	COG0825	malonyl-CoA metabolic process
CG027_RS08650	COG0037	tRNA processing
CG027_RS08655	COG0527	aspartate kinase activity
CG027_RS08680	COG1250	3-hydroxyacyl-CoA dehydrogenase
CG027_RS08685	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CG027_RS08685	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CG027_RS08700	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CG027_RS08705	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
CG027_RS08710	COG1028	Short-chain dehydrogenase reductase Sdr
CG027_RS08720	COG0583	DNA-binding transcription factor activity
CG027_RS08745	COG3842	ATPase activity
CG027_RS08755	COG1902	pentaerythritol trinitrate reductase activity
CG027_RS08755	COG0446	pyridine nucleotide-disulphide oxidoreductase
CG027_RS08760	COG1414	Transcriptional regulator
CG027_RS08765	COG1832	CoA-binding protein
CG027_RS08775	COG0251	oxidation-reduction process
CG027_RS08800	COG1902	pentaerythritol trinitrate reductase activity
CG027_RS08810	COG1215	transferase activity, transferring glycosyl groups
CG027_RS08815	COG1649	PFAM Uncharacterised BCR, COG1649
CG027_RS08815	COG0726	polysaccharide deacetylase
CG027_RS08835	COG1846	Transcriptional regulator
CG027_RS08850	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CG027_RS08860	COG0556	nucleotide-excision repair
CG027_RS08865	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CG027_RS08875	COG1104	cysteine desulfurase activity
CG027_RS08880	COG0822	iron-sulfur transferase activity
CG027_RS08885	COG0316	Belongs to the HesB IscA family
CG027_RS08890	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CG027_RS08895	COG0443	Heat shock 70 kDa protein
CG027_RS08900	COG0633	Ferredoxin
CG027_RS08920	COG1024	Enoyl-CoA hydratase
CG027_RS08935	COG3395	kinase activity
CG027_RS08955	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CG027_RS08965	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CG027_RS08995	COG0747	negative chemotaxis
CG027_RS09000	COG0601	transmembrane transport
CG027_RS09005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CG027_RS09010	COG4172	Belongs to the ABC transporter superfamily
CG027_RS09015	COG0154	amidase activity
CG027_RS09060	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CG027_RS09065	COG0425	Belongs to the sulfur carrier protein TusA family
CG027_RS09075	COG0228	four-way junction DNA binding
CG027_RS09080	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CG027_RS09085	COG0336	Belongs to the RNA methyltransferase TrmD family
CG027_RS09090	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CG027_RS09115	COG0642	Histidine kinase
CG027_RS09130	COG0525	valine-tRNA ligase activity
CG027_RS09135	COG0105	UTP biosynthetic process
CG027_RS09140	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CG027_RS09150	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CG027_RS09155	COG0124	histidyl-tRNA synthetase
CG027_RS09160	COG2976	Protein conserved in bacteria
CG027_RS09165	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CG027_RS09170	COG1160	GTP binding
CG027_RS09175	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CG027_RS09180	COG1923	regulation of RNA biosynthetic process
CG027_RS09185	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CG027_RS09190	COG0330	HflC and HflK could
CG027_RS09195	COG0330	HflC and HflK could
CG027_RS09200	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CG027_RS09205	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CG027_RS09210	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CG027_RS09215	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CG027_RS09230	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CG027_RS09265	COG0628	permease
CG027_RS09270	COG0842	Transport permease protein
CG027_RS09275	COG1131	(ABC) transporter
CG027_RS09345	COG0156	8-amino-7-oxononanoate synthase activity
CG027_RS09355	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CG027_RS09355	COG4106	trans-aconitate 2-methyltransferase activity
CG027_RS09360	COG1380	Effector of murein hydrolase LrgA
CG027_RS09380	COG3284	Transcriptional regulator
CG027_RS09385	COG1012	belongs to the aldehyde dehydrogenase family
CG027_RS09400	COG2733	membrane
CG027_RS09405	COG0583	DNA-binding transcription factor activity
CG027_RS09410	COG0384	phenazine biosynthesis protein PhzF
CG027_RS09415	COG5507	3-demethylubiquinone-9 3-methyltransferase
CG027_RS09420	COG2169	Transcriptional regulator
CG027_RS09450	COG0659	secondary active sulfate transmembrane transporter activity
CG027_RS09475	COG1132	(ABC) transporter
CG027_RS09525	COG2207	Transcriptional regulator
CG027_RS09665	COG2346	COG2346, Truncated hemoglobins
CG027_RS09695	COG0583	DNA-binding transcription factor activity
CG027_RS09710	COG0183	Belongs to the thiolase family
CG027_RS09725	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CG027_RS09730	COG0633	Ferredoxin
CG027_RS09740	COG1024	Enoyl-CoA hydratase
CG027_RS09750	COG4638	Rieske (2fe-2S)
CG027_RS09760	COG0559	Belongs to the binding-protein-dependent transport system permease family
CG027_RS09780	COG2224	Isocitrate lyase
CG027_RS09785	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CG027_RS09785	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CG027_RS09795	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CG027_RS09800	COG0322	excinuclease ABC activity
CG027_RS09805	COG1472	Belongs to the glycosyl hydrolase 3 family
CG027_RS09810	COG0736	holo-[acyl-carrier-protein] synthase activity
CG027_RS09815	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CG027_RS09825	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CG027_RS09830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CG027_RS09855	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CG027_RS09870	COG2032	superoxide dismutase activity
CG027_RS09885	COG1024	Enoyl-CoA hydratase
CG027_RS09895	COG1802	Transcriptional regulator
CG027_RS09905	COG0183	Belongs to the thiolase family
CG027_RS09910	COG1942	4-Oxalocrotonate Tautomerase
CG027_RS09920	COG4176	ABC-type proline glycine betaine transport system permease component
CG027_RS09940	COG2814	Major facilitator Superfamily
CG027_RS09945	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CG027_RS09950	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CG027_RS09985	COG2814	Major facilitator Superfamily
CG027_RS09990	COG0495	leucyl-tRNA aminoacylation
CG027_RS10005	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CG027_RS10015	COG0154	amidase activity
CG027_RS10020	COG1250	3-hydroxyacyl-CoA dehydrogenase
CG027_RS10075	COG0427	acetyl-CoA hydrolase
CG027_RS10080	COG0583	DNA-binding transcription factor activity
CG027_RS10100	COG0730	response to heat
CG027_RS10105	COG0697	spore germination
CG027_RS10140	COG2885	chlorophyll binding
CG027_RS10170	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CG027_RS10175	COG3384	dioxygenase
CG027_RS10190	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CG027_RS10195	COG3474	cytochrome
CG027_RS10205	COG1595	DNA-templated transcription, initiation
CG027_RS10220	COG2204	response regulator
CG027_RS10260	COG4964	Belongs to the GSP D family
CG027_RS10315	COG1846	Transcriptional regulator
CG027_RS10320	COG4172	Belongs to the ABC transporter superfamily
CG027_RS10325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CG027_RS10330	COG0601	transmembrane transport
CG027_RS10335	COG0747	negative chemotaxis
CG027_RS10345	COG0598	Magnesium transport protein CorA
CG027_RS10350	COG0210	DNA helicase
CG027_RS10365	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CG027_RS10370	COG1012	belongs to the aldehyde dehydrogenase family
CG027_RS10375	COG0483	inositol monophosphate 1-phosphatase activity
CG027_RS10380	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CG027_RS10390	COG1045	serine acetyltransferase
CG027_RS10395	COG0166	Belongs to the GPI family
CG027_RS10410	COG2197	response regulator
CG027_RS10430	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CG027_RS10450	COG1028	Short-chain dehydrogenase reductase Sdr
CG027_RS10455	COG0183	Belongs to the thiolase family
CG027_RS10465	COG1024	Enoyl-CoA hydratase
CG027_RS10480	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CG027_RS10485	COG0583	DNA-binding transcription factor activity
CG027_RS10490	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CG027_RS10495	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CG027_RS10500	COG0740	serine-type endopeptidase activity
CG027_RS10505	COG0544	peptidyl-prolyl cis-trans isomerase activity
CG027_RS10515	COG1278	Cold shock
CG027_RS10525	COG1278	Cold shock
CG027_RS10560	COG2171	N-acyltransferase activity
CG027_RS10565	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CG027_RS10570	COG2890	protein-(glutamine-N5) methyltransferase activity
CG027_RS10575	COG0488	(ABC) transporter
CG027_RS10580	COG4771	TonB-dependent receptor
CG027_RS10585	COG0210	DNA helicase
CG027_RS10605	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CG027_RS10610	COG0196	riboflavin kinase activity
CG027_RS10615	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CG027_RS10620	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CG027_RS10625	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CG027_RS10635	COG1522	sequence-specific DNA binding
CG027_RS10655	COG2951	lytic endotransglycosylase activity
CG027_RS10660	COG2833	Protein of unknown function (DUF455)
CG027_RS10680	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CG027_RS10680	COG0189	ligase activity
CG027_RS10685	COG1181	Belongs to the D-alanine--D-alanine ligase family
CG027_RS10685	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CG027_RS10690	COG3237	CsbD-like
CG027_RS10700	COG2823	Periplasmic or secreted lipoprotein
CG027_RS10715	COG4181	ATPase activity
CG027_RS10725	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CG027_RS10730	COG0584	glycerophosphoryl diester phosphodiesterase
CG027_RS10735	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CG027_RS10745	COG0678	peroxiredoxin activity
CG027_RS10745	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CG027_RS10755	COG0789	Transcriptional regulator
CG027_RS10760	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CG027_RS10790	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CG027_RS10795	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CG027_RS10805	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CG027_RS10810	COG2252	PERMEase
CG027_RS10820	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CG027_RS10855	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CG027_RS10860	COG2358	TRAP transporter, solute receptor (TAXI family
CG027_RS10900	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CG027_RS10905	COG1366	Belongs to the anti-sigma-factor antagonist family
CG027_RS10910	COG2172	sigma factor antagonist activity
CG027_RS10915	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CG027_RS10925	COG2770	Histidine kinase
CG027_RS10925	COG2208	phosphoserine phosphatase activity
CG027_RS10950	COG1595	DNA-templated transcription, initiation
CG027_RS10965	COG4792	protein secretion
CG027_RS10970	COG4791	protein targeting
CG027_RS10975	COG4794	Type iii secretion
CG027_RS10980	COG4790	Type iii secretion
CG027_RS11015	COG4669	(LipO)protein
CG027_RS11080	COG4789	Type iii secretion
CG027_RS11110	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CG027_RS11115	COG0840	transmembrane signaling receptor activity
CG027_RS11120	COG2233	PERMEase
CG027_RS11145	COG1840	ABC-type Fe3 transport system, periplasmic component
CG027_RS11150	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CG027_RS11155	COG1178	ABC-type Fe3 transport system permease component
CG027_RS11160	COG3842	ATPase activity
CG027_RS11165	COG0583	DNA-binding transcription factor activity
CG027_RS11185	COG0501	Belongs to the peptidase M48B family
CG027_RS11195	COG0697	spore germination
CG027_RS11205	COG1846	Transcriptional regulator
CG027_RS11215	COG1566	PFAM secretion protein HlyD family protein
CG027_RS11220	COG2814	Major facilitator Superfamily
CG027_RS11225	COG0473	3-isopropylmalate dehydrogenase activity
CG027_RS11235	COG0747	negative chemotaxis
CG027_RS11245	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CG027_RS11260	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CG027_RS11285	COG1012	belongs to the aldehyde dehydrogenase family
CG027_RS11295	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CG027_RS11300	COG1115	amino acid carrier protein
CG027_RS11305	COG0433	COG0433 Predicted ATPase
CG027_RS11310	COG0217	transcriptional regulatory protein
CG027_RS11315	COG0151	Belongs to the GarS family
CG027_RS11320	COG0408	coproporphyrinogen oxidase activity
CG027_RS11325	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CG027_RS11330	COG0799	negative regulation of ribosome biogenesis
CG027_RS11335	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CG027_RS11340	COG0424	maF-like protein
CG027_RS11345	COG3468	outer membrane autotransporter barrel domain protein
CG027_RS11385	COG1530	ribonuclease E activity
CG027_RS11390	COG0077	Prephenate dehydratase
CG027_RS11405	COG1132	(ABC) transporter
CG027_RS11410	COG0859	PFAM glycosyl transferase family 9
CG027_RS11435	COG2194	sulfuric ester hydrolase activity
CG027_RS11440	COG0438	transferase activity, transferring glycosyl groups
CG027_RS11445	COG0463	Glycosyl transferase, family 2
CG027_RS11450	COG0726	polysaccharide deacetylase
CG027_RS11455	COG0438	transferase activity, transferring glycosyl groups
CG027_RS11470	COG1643	Atp-dependent helicase
CG027_RS11475	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CG027_RS11475	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CG027_RS11480	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CG027_RS11490	COG0704	Plays a role in the regulation of phosphate uptake
CG027_RS11495	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CG027_RS11500	COG1960	acyl-CoA dehydrogenase activity
CG027_RS11525	COG1177	transmembrane transport
CG027_RS11530	COG1176	ABC-type spermidine putrescine transport system, permease component I
CG027_RS11535	COG3842	ATPase activity
CG027_RS11540	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CG027_RS11555	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CG027_RS11560	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CG027_RS11570	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CG027_RS11570	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CG027_RS11585	COG0372	Belongs to the citrate synthase family
CG027_RS11590	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CG027_RS11595	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CG027_RS11600	COG1053	succinate dehydrogenase
CG027_RS11605	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CG027_RS11610	COG2009	succinate dehydrogenase
CG027_RS11615	COG2188	Transcriptional regulator
CG027_RS11620	COG0039	L-malate dehydrogenase activity
CG027_RS11650	COG1981	membrane
CG027_RS11675	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CG027_RS11685	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CG027_RS11715	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CG027_RS11720	COG0148	phosphopyruvate hydratase activity
CG027_RS11730	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CG027_RS11735	COG0504	CTP synthase activity
CG027_RS11760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CG027_RS11770	COG0747	negative chemotaxis
CG027_RS11775	COG4172	Belongs to the ABC transporter superfamily
CG027_RS11780	COG1446	asparaginase
CG027_RS11810	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CG027_RS11825	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CG027_RS11830	COG0697	spore germination
CG027_RS11835	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CG027_RS11845	COG3193	protein, possibly involved in utilization of glycolate and propanediol
CG027_RS11855	COG0791	NLP P60 protein
CG027_RS11880	COG0583	DNA-binding transcription factor activity
CG027_RS11895	COG0583	DNA-binding transcription factor activity
CG027_RS11905	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CG027_RS11920	COG0670	Belongs to the BI1 family
CG027_RS11925	COG3181	Tripartite tricarboxylate transporter family receptor
CG027_RS11940	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CG027_RS11950	COG1381	Involved in DNA repair and RecF pathway recombination
CG027_RS11955	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CG027_RS11960	COG0571	ribonuclease III activity
CG027_RS11965	COG0681	Belongs to the peptidase S26 family
CG027_RS11970	COG0481	GTPase activity
CG027_RS11975	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CG027_RS12000	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CG027_RS12005	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CG027_RS12020	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CG027_RS12025	COG0416	fatty acid biosynthetic process
CG027_RS12030	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CG027_RS12035	COG1399	metal-binding, possibly nucleic acid-binding protein
CG027_RS12040	COG0424	maF-like protein
CG027_RS12050	COG3023	N-Acetylmuramoyl-L-alanine amidase
CG027_RS12065	COG3022	response to hydroperoxide
CG027_RS12080	COG0135	phosphoribosylanthranilate isomerase activity
CG027_RS12095	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CG027_RS12100	COG0101	tRNA pseudouridine synthase activity
CG027_RS12110	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CG027_RS12115	COG0473	3-isopropylmalate dehydrogenase activity
CG027_RS12120	COG0066	3-isopropylmalate dehydratase activity
CG027_RS12125	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CG027_RS12135	COG1122	ATPase activity
CG027_RS12170	COG0243	molybdopterin cofactor binding
CG027_RS12170	COG3383	formate dehydrogenase (NAD+) activity
CG027_RS12200	COG0489	protein tyrosine kinase activity
CG027_RS12205	COG0746	molybdenum cofactor guanylyltransferase activity
CG027_RS12210	COG0303	'Molybdopterin
CG027_RS12215	COG1763	Mo-molybdopterin cofactor biosynthetic process
CG027_RS12225	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CG027_RS12230	COG5001	Diguanylate cyclase
CG027_RS12250	COG3842	ATPase activity
CG027_RS12260	COG0406	alpha-ribazole phosphatase activity
CG027_RS12270	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CG027_RS12275	COG0505	Belongs to the CarA family
CG027_RS12280	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CG027_RS12315	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CG027_RS12320	COG1960	acyl-CoA dehydrogenase activity
CG027_RS12330	COG2867	negative regulation of translational initiation
CG027_RS12340	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CG027_RS12345	COG3706	GGDEF domain
CG027_RS12350	COG0330	HflC and HflK could
CG027_RS12365	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CG027_RS12365	COG0519	Catalyzes the synthesis of GMP from XMP
CG027_RS12375	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CG027_RS12380	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CG027_RS12385	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CG027_RS12390	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CG027_RS12400	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CG027_RS12405	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CG027_RS12410	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CG027_RS12415	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CG027_RS12420	COG0750	zinc metalloprotease
CG027_RS12425	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CG027_RS12435	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CG027_RS12440	COG0233	cytoplasmic translational termination
CG027_RS12445	COG0528	UMP kinase activity
CG027_RS12450	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CG027_RS12455	COG0052	Belongs to the universal ribosomal protein uS2 family
CG027_RS12460	COG0024	Methionine aminopeptidase
CG027_RS12465	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CG027_RS12495	COG0285	dihydrofolate synthase activity
CG027_RS12530	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CG027_RS12540	COG1677	Flagellar hook-basal body complex protein FliE
CG027_RS12550	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CG027_RS12560	COG1157	protein secretion by the type III secretion system
CG027_RS12585	COG1580	Controls the rotational direction of flagella during chemotaxis
CG027_RS12605	COG1338	Plays a role in the flagellum-specific transport system
CG027_RS12625	COG0840	transmembrane signaling receptor activity
CG027_RS12630	COG0840	transmembrane signaling receptor activity
CG027_RS12635	COG0840	transmembrane signaling receptor activity
CG027_RS12645	COG1256	bacterial-type flagellum assembly
CG027_RS12655	COG1706	bacterial-type flagellum-dependent cell motility
CG027_RS12660	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CG027_RS12675	COG1749	Flagellar hook protein flgE
CG027_RS12685	COG1558	bacterial-type flagellum-dependent cell motility
CG027_RS12690	COG1815	bacterial-type flagellum-dependent cell motility
CG027_RS12730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG027_RS12735	COG0765	amino acid transport
CG027_RS12740	COG1126	abc transporter atp-binding protein
CG027_RS12755	COG4948	Mandelate Racemase Muconate Lactonizing
CG027_RS12760	COG3181	Tripartite tricarboxylate transporter family receptor
CG027_RS12770	COG0066	3-isopropylmalate dehydratase activity
CG027_RS12785	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CG027_RS12795	COG3181	Tripartite tricarboxylate transporter family receptor
CG027_RS12805	COG1802	Transcriptional regulator
CG027_RS12820	COG0583	DNA-binding transcription factor activity
CG027_RS12840	COG1695	Transcriptional regulator
CG027_RS12850	COG3568	Endonuclease Exonuclease Phosphatase
CG027_RS12855	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CG027_RS12905	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CG027_RS12915	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CG027_RS12935	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CG027_RS12965	COG0667	Aldo Keto reductase
CG027_RS12980	COG2259	Doxx family
CG027_RS13020	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CG027_RS13040	COG0386	Belongs to the glutathione peroxidase family
CG027_RS13045	COG0625	glutathione transferase activity
CG027_RS13060	COG0095	Lipoate-protein ligase
CG027_RS13075	COG0688	phosphatidylethanolamine metabolic process
CG027_RS13085	COG1464	Belongs to the NlpA lipoprotein family
CG027_RS13100	COG2363	Small membrane protein
CG027_RS13125	COG3842	ATPase activity
CG027_RS13130	COG0395	ABC-type sugar transport system, permease component
CG027_RS13135	COG1175	transmembrane transport
CG027_RS13140	COG1653	transport
CG027_RS13150	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CG027_RS13170	COG0559	Belongs to the binding-protein-dependent transport system permease family
CG027_RS13190	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CG027_RS13220	COG2311	Membrane
CG027_RS13245	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CG027_RS13255	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CG027_RS13260	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CG027_RS13265	COG1760	l-serine dehydratase
CG027_RS13270	COG1283	sodium-dependent phosphate transmembrane transporter activity
CG027_RS13275	COG0412	Dienelactone hydrolase
CG027_RS13290	COG1611	Belongs to the LOG family
CG027_RS13310	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CG027_RS13315	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CG027_RS13320	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CG027_RS13325	COG2251	uridine kinase activity
CG027_RS13325	COG0195	Participates in both transcription termination and antitermination
CG027_RS13330	COG0779	Required for maturation of 30S ribosomal subunits
CG027_RS13335	COG1187	pseudouridine synthase activity
CG027_RS13340	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CG027_RS13350	COG0583	DNA-binding transcription factor activity
CG027_RS13360	COG0523	cobalamin synthesis protein
CG027_RS13380	COG0625	glutathione transferase activity
CG027_RS13385	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CG027_RS13390	COG1047	Peptidyl-prolyl cis-trans
CG027_RS13395	COG2003	Belongs to the UPF0758 family
CG027_RS13400	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CG027_RS13405	COG3483	tryptophan 2,3-dioxygenase activity
CG027_RS13410	COG0254	rRNA binding
CG027_RS13420	COG0534	Mate efflux family protein
CG027_RS13440	COG2304	oxidoreductase activity
CG027_RS13460	COG1028	Short-chain dehydrogenase reductase Sdr
CG027_RS13465	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CG027_RS13470	COG1562	ergosterol biosynthetic process
CG027_RS13475	COG1562	ergosterol biosynthetic process
CG027_RS13480	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CG027_RS13480	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CG027_RS13485	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CG027_RS13495	COG0842	Transport permease protein
CG027_RS13500	COG1131	(ABC) transporter
CG027_RS13520	COG1477	protein flavinylation
CG027_RS13535	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CG027_RS13550	COG5564	TIM-barrel signal transduction protein
CG027_RS13555	COG5441	Belongs to the UPF0261 family
CG027_RS13565	COG3468	outer membrane autotransporter barrel domain protein
CG027_RS13585	COG0542	response to heat
CG027_RS13590	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CG027_RS13605	COG0494	nUDIX hydrolase
CG027_RS13610	COG3530	Putative quorum-sensing-regulated virulence factor
CG027_RS13620	COG1595	DNA-templated transcription, initiation
CG027_RS13625	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CG027_RS13660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG027_RS13665	COG0765	amino acid transport
CG027_RS13670	COG0765	amino acid transport
CG027_RS13700	COG3539	Fimbrial protein
CG027_RS13710	COG2050	protein possibly involved in aromatic compounds catabolism
CG027_RS13715	COG1024	Enoyl-CoA hydratase
CG027_RS13720	COG1012	belongs to the aldehyde dehydrogenase family
CG027_RS13740	COG2151	metal-sulfur cluster biosynthetic enzyme
CG027_RS13745	COG3396	Phenylacetate-CoA oxygenase
CG027_RS13750	COG3460	Phenylacetate-CoA oxygenase
CG027_RS13755	COG3396	Phenylacetate-CoA oxygenase
CG027_RS13760	COG3327	negative regulation of DNA-templated transcription, initiation
CG027_RS13770	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CG027_RS13775	COG0501	Belongs to the peptidase M48B family
CG027_RS13780	COG1162	GTPase activity
CG027_RS13795	COG0601	transmembrane transport
CG027_RS13800	COG0747	negative chemotaxis
CG027_RS13845	COG0668	transmembrane transport
CG027_RS13850	COG0165	Argininosuccinate lyase
CG027_RS13870	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CG027_RS13875	COG0303	'Molybdopterin
CG027_RS13880	COG0521	Mo-molybdopterin cofactor biosynthetic process
CG027_RS13895	COG0315	cyclic pyranopterin monophosphate synthase activity
CG027_RS13905	COG0412	Dienelactone hydrolase
CG027_RS13915	COG0678	peroxiredoxin activity
CG027_RS13925	COG0697	spore germination
CG027_RS13930	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CG027_RS13955	COG0789	Transcriptional regulator
CG027_RS13975	COG1028	Short-chain dehydrogenase reductase Sdr
CG027_RS13985	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CG027_RS13990	COG1845	cytochrome c oxidase, subunit III
CG027_RS13995	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CG027_RS14005	COG0477	Major facilitator Superfamily
CG027_RS14040	COG1309	transcriptional regulator
CG027_RS14045	COG2271	Major facilitator Superfamily
CG027_RS14080	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CG027_RS14080	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CG027_RS14080	COG0506	proline dehydrogenase activity
CG027_RS14090	COG3008	intermembrane lipid transfer
CG027_RS14090	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CG027_RS14095	COG2995	paraquat-inducible protein a
CG027_RS14100	COG0542	response to heat
CG027_RS14105	COG4953	penicillin-binding protein 1C
CG027_RS14115	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CG027_RS14120	COG1278	Cold shock
CG027_RS14130	COG0183	Belongs to the thiolase family
CG027_RS14135	COG0038	chloride channel
CG027_RS14140	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CG027_RS14145	COG1570	exodeoxyribonuclease VII activity
CG027_RS14155	COG0811	peptide transport
CG027_RS14160	COG0848	biopolymer transport protein
CG027_RS14165	COG1663	tetraacyldisaccharide 4'-kinase activity
CG027_RS14170	COG2835	tetraacyldisaccharide 4'-kinase activity
CG027_RS14175	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CG027_RS14180	COG0563	adenylate kinase activity
CG027_RS14190	COG0728	peptidoglycan biosynthetic process
CG027_RS14200	COG0268	Binds directly to 16S ribosomal RNA
CG027_RS14235	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CG027_RS14260	COG0436	Aminotransferase
CG027_RS14265	COG3737	Protein of unknown function (DUF498/DUF598)
CG027_RS14270	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CG027_RS14275	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CG027_RS14280	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CG027_RS14290	COG0305	Participates in initiation and elongation during chromosome replication
CG027_RS14300	COG0359	binds to the 23S rRNA
CG027_RS14305	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CG027_RS14310	COG2965	DNA replication, synthesis of RNA primer
CG027_RS14315	COG0360	Binds together with S18 to 16S ribosomal RNA
CG027_RS14320	COG1469	GTP cyclohydrolase I activity
CG027_RS14325	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CG027_RS14330	COG0142	geranyltranstransferase activity
CG027_RS14335	COG1722	exodeoxyribonuclease VII activity
CG027_RS14345	COG3181	Tripartite tricarboxylate transporter family receptor
CG027_RS14365	COG2239	Acts as a magnesium transporter
CG027_RS14375	COG2855	membrane
CG027_RS14385	COG1473	amidohydrolase
CG027_RS14390	COG0318	PFAM AMP-dependent synthetase and ligase
CG027_RS14415	COG1501	Belongs to the glycosyl hydrolase 31 family
CG027_RS14420	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CG027_RS14425	COG2011	ABC-type metal ion transport system permease component
CG027_RS14445	COG1454	alcohol dehydrogenase
CG027_RS14475	COG2186	Transcriptional regulator
CG027_RS14480	COG3181	Tripartite tricarboxylate transporter family receptor
CG027_RS14500	COG1175	transmembrane transport
CG027_RS14505	COG0395	ABC-type sugar transport system, permease component
CG027_RS14510	COG3842	ATPase activity
CG027_RS14525	COG1653	transport
CG027_RS14545	COG2818	Glycosylase
CG027_RS14550	COG2982	Protein involved in outer membrane biogenesis
CG027_RS14560	COG1309	transcriptional regulator
CG027_RS14565	COG1028	Short-chain dehydrogenase reductase Sdr
CG027_RS14625	COG0583	DNA-binding transcription factor activity
CG027_RS14630	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CG027_RS14635	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CG027_RS14650	COG1028	Short-chain dehydrogenase reductase Sdr
CG027_RS14655	COG0477	Major facilitator Superfamily
CG027_RS14665	COG0583	DNA-binding transcription factor activity
CG027_RS14670	COG1448	Aminotransferase
CG027_RS14675	COG1418	mRNA catabolic process
CG027_RS14700	COG1063	alcohol dehydrogenase
CG027_RS14720	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CG027_RS14730	COG0318	PFAM AMP-dependent synthetase and ligase
CG027_RS14740	COG1522	sequence-specific DNA binding
CG027_RS14745	COG3181	Tripartite tricarboxylate transporter family receptor
CG027_RS14750	COG0307	riboflavin synthase, alpha
CG027_RS14755	COG0154	amidase activity
CG027_RS14775	COG2807	transmembrane transport
CG027_RS14780	COG0590	tRNA wobble adenosine to inosine editing
CG027_RS14790	COG0583	DNA-binding transcription factor activity
CG027_RS14825	COG0559	Belongs to the binding-protein-dependent transport system permease family
CG027_RS14830	COG0251	oxidation-reduction process
CG027_RS14835	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CG027_RS14845	COG1414	Transcriptional regulator
CG027_RS14850	COG1028	Short-chain dehydrogenase reductase Sdr
CG027_RS14865	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CG027_RS14880	COG1024	Enoyl-CoA hydratase
CG027_RS14885	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CG027_RS14890	COG0154	amidase activity
CG027_RS14930	COG3909	cytochrome
CG027_RS14935	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CG027_RS14940	COG0625	glutathione transferase activity
CG027_RS14945	COG0730	response to heat
CG027_RS14950	COG0482	sulfurtransferase activity
CG027_RS14955	COG0583	DNA-binding transcription factor activity
CG027_RS14995	COG2819	hydrolase of the alpha beta superfamily
CG027_RS15000	COG0247	lactate metabolic process
CG027_RS15005	COG0277	FAD linked oxidase domain protein
CG027_RS15010	COG0277	FAD linked oxidase domain protein
CG027_RS15015	COG0277	FAD linked oxidase domain protein
CG027_RS15020	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CG027_RS15020	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CG027_RS15020	COG3210	domain, Protein
CG027_RS15020	COG3064	Membrane
CG027_RS15020	COG3064	Membrane
CG027_RS15020	COG3210	domain, Protein
CG027_RS15025	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CG027_RS15030	COG0312	modulator of DNA gyrase
CG027_RS15065	COG1666	GTP binding
CG027_RS15110	COG3220	belongs to the UPF0276 family
CG027_RS15130	COG0640	Transcriptional regulator
CG027_RS15135	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CG027_RS15140	COG1845	cytochrome c oxidase, subunit III
CG027_RS15145	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CG027_RS15155	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CG027_RS15190	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CG027_RS15195	COG0583	DNA-binding transcription factor activity
CG027_RS15230	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CG027_RS15230	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CG027_RS15245	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CG027_RS15250	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CG027_RS15260	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CG027_RS15275	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CG027_RS15280	COG0316	Belongs to the HesB IscA family
CG027_RS15290	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CG027_RS15295	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CG027_RS15300	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CG027_RS15305	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CG027_RS15310	COG0312	modulator of DNA gyrase
CG027_RS15315	COG3028	Belongs to the UPF0307 family
CG027_RS15330	COG1116	anion transmembrane transporter activity
CG027_RS15335	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CG027_RS15340	COG1335	isochorismatase
CG027_RS15345	COG0346	lactoylglutathione lyase activity
CG027_RS15350	COG0513	Belongs to the DEAD box helicase family
CG027_RS15355	COG3069	C4-dicarboxylate transmembrane transporter activity
CG027_RS15360	COG1802	Transcriptional regulator
CG027_RS15375	COG1042	CoA-binding domain protein
CG027_RS15375	COG0045	succinate-CoA ligase (ADP-forming) activity
CG027_RS15375	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CG027_RS15380	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CG027_RS15395	COG1522	sequence-specific DNA binding
CG027_RS15430	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CG027_RS15435	COG1696	Membrane protein involved in D-alanine export
CG027_RS15460	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CG027_RS15475	COG0439	Biotin carboxylase
CG027_RS15480	COG0511	ligase activity, forming carbon-carbon bonds
CG027_RS15485	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CG027_RS15490	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CG027_RS15495	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CG027_RS15500	COG3150	esterase
CG027_RS15505	COG0557	exoribonuclease II activity
CG027_RS15515	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CG027_RS15535	COG1522	sequence-specific DNA binding
CG027_RS15540	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CG027_RS15545	COG1028	Short-chain dehydrogenase reductase Sdr
CG027_RS15565	COG0653	protein targeting
CG027_RS15570	COG0739	heme binding
CG027_RS15580	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CG027_RS15585	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CG027_RS15595	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CG027_RS15600	COG1181	Belongs to the D-alanine--D-alanine ligase family
CG027_RS15605	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CG027_RS15610	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CG027_RS15620	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CG027_RS15625	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CG027_RS15630	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CG027_RS15640	COG3116	cell division
CG027_RS15645	COG0275	rRNA processing
CG027_RS15650	COG2001	Belongs to the MraZ family
CG027_RS15660	COG0488	(ABC) transporter
CG027_RS15665	COG0418	dihydroorotase activity
CG027_RS15670	COG1473	amidohydrolase
CG027_RS15720	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CG027_RS15725	COG4654	Cytochrome c, class I
CG027_RS15730	COG0129	dihydroxy-acid dehydratase activity
CG027_RS15735	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CG027_RS15785	COG2084	Dehydrogenase
CG027_RS15805	COG2096	Adenosyltransferase
CG027_RS15820	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CG027_RS15825	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CG027_RS15835	COG0523	cobalamin synthesis protein
CG027_RS15840	COG0735	belongs to the Fur family
CG027_RS15855	COG0803	Belongs to the bacterial solute-binding protein 9 family
CG027_RS15865	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CG027_RS15875	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CG027_RS15885	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CG027_RS15890	COG1560	Kdo2-lipid A biosynthetic process
CG027_RS15900	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CG027_RS15915	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CG027_RS15920	COG1950	PFAM Membrane protein of
CG027_RS15935	COG0583	DNA-binding transcription factor activity
CG027_RS15945	COG0477	Major facilitator Superfamily
CG027_RS15960	COG0617	tRNA 3'-terminal CCA addition
CG027_RS15970	COG0513	Belongs to the DEAD box helicase family
CG027_RS15975	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CG027_RS15985	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CG027_RS15990	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CG027_RS16065	COG0405	Gamma-glutamyltransferase
CG027_RS16075	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CG027_RS16105	COG1309	transcriptional regulator
CG027_RS16120	COG0745	RESPONSE REGULATOR receiver
CG027_RS16170	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CG027_RS16195	COG0582	viral genome integration into host DNA
CG027_RS16200	COG0012	GTP binding
CG027_RS16210	COG0193	aminoacyl-tRNA hydrolase activity
CG027_RS16215	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CG027_RS16220	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CG027_RS16230	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CG027_RS16235	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CG027_RS16245	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CG027_RS16270	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CG027_RS16280	COG1368	sulfuric ester hydrolase activity
CG027_RS16285	COG0642	Histidine kinase
CG027_RS16290	COG0745	RESPONSE REGULATOR receiver
CG027_RS16295	COG0277	FAD linked oxidase domain protein
CG027_RS16310	COG0166	Belongs to the GPI family
CG027_RS16315	COG0438	transferase activity, transferring glycosyl groups
CG027_RS16320	COG0438	transferase activity, transferring glycosyl groups
CG027_RS16335	COG0438	transferase activity, transferring glycosyl groups
CG027_RS16350	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CG027_RS16355	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CG027_RS16360	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
CG027_RS16370	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CG027_RS16380	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CG027_RS16385	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CG027_RS16395	COG0747	negative chemotaxis
CG027_RS16400	COG0601	transmembrane transport
CG027_RS16405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CG027_RS16425	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CG027_RS16430	COG0830	nickel cation binding
CG027_RS16440	COG0804	urea catabolic process
CG027_RS16445	COG0832	Belongs to the urease beta subunit family
CG027_RS16455	COG0831	urea catabolic process
CG027_RS16460	COG0829	nickel cation binding
CG027_RS16490	COG2188	Transcriptional regulator
CG027_RS16515	COG2719	SpoVR family
CG027_RS16520	COG2718	Belongs to the UPF0229 family
CG027_RS16540	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CG027_RS16555	COG1960	acyl-CoA dehydrogenase activity
CG027_RS16605	COG2030	dehydratase
CG027_RS16655	COG0328	RNA-DNA hybrid ribonuclease activity
CG027_RS16660	COG2226	methyltransferase
CG027_RS16665	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CG027_RS16670	COG0741	lytic transglycosylase activity
CG027_RS16670	COG1388	LysM domain
CG027_RS16690	COG2979	Protein of unknown function (DUF533)
CG027_RS16725	COG1271	oxidase subunit
CG027_RS16730	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CG027_RS16735	COG0850	regulation of cytokinetic process
CG027_RS16740	COG2894	cell division
CG027_RS16745	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CG027_RS16780	COG0601	transmembrane transport
CG027_RS16790	COG1215	transferase activity, transferring glycosyl groups
CG027_RS16805	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CG027_RS16815	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CG027_RS16835	COG0318	PFAM AMP-dependent synthetase and ligase
CG027_RS16840	COG2188	Transcriptional regulator
CG027_RS16845	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CG027_RS16850	COG2814	Major facilitator Superfamily
CG027_RS16860	COG0259	pyridoxamine-phosphate oxidase activity
CG027_RS16865	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CG027_RS16880	COG0583	DNA-binding transcription factor activity
CG027_RS16905	COG0134	indole-3-glycerol-phosphate synthase activity
CG027_RS16910	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CG027_RS16915	COG0512	Glutamine amidotransferase of anthranilate synthase
CG027_RS16925	COG0546	phosphoglycolate phosphatase activity
CG027_RS16930	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CG027_RS16935	COG2967	ApaG domain
CG027_RS16940	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CG027_RS16945	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CG027_RS16950	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CG027_RS16955	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CG027_RS16965	COG0037	tRNA processing
CG027_RS16975	COG3634	alkyl hydroperoxide reductase activity
CG027_RS16980	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CG027_RS16985	COG1024	Enoyl-CoA hydratase
CG027_RS17010	COG0356	it plays a direct role in the translocation of protons across the membrane
CG027_RS17020	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CG027_RS17025	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CG027_RS17030	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CG027_RS17035	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CG027_RS17040	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CG027_RS17045	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CG027_RS17055	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CG027_RS17060	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CG027_RS17065	COG0210	DNA helicase
CG027_RS17075	COG2195	Cleaves the N-terminal amino acid of tripeptides
CG027_RS17085	COG4172	Belongs to the ABC transporter superfamily
CG027_RS17090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CG027_RS17095	COG0601	transmembrane transport
CG027_RS17115	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CG027_RS17120	COG1024	Enoyl-CoA hydratase
CG027_RS17125	COG1024	Enoyl-CoA hydratase
CG027_RS17180	COG2132	Multicopper oxidase
CG027_RS17190	COG1250	3-hydroxyacyl-CoA dehydrogenase
CG027_RS17190	COG1024	Enoyl-CoA hydratase
CG027_RS17200	COG1414	Transcriptional regulator
CG027_RS17210	COG0154	amidase activity
CG027_RS17240	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CG027_RS17245	COG3568	Endonuclease Exonuclease Phosphatase
CG027_RS17250	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CG027_RS17285	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CG027_RS17295	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CG027_RS17310	COG1137	ATPase activity
CG027_RS17325	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CG027_RS17330	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CG027_RS17330	COG2010	Cytochrome c
CG027_RS17340	COG1660	Displays ATPase and GTPase activities
CG027_RS17345	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CG027_RS17380	COG3181	Tripartite tricarboxylate transporter family receptor
CG027_RS17390	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CG027_RS17395	COG2890	protein-(glutamine-N5) methyltransferase activity
CG027_RS17400	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CG027_RS17405	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CG027_RS17455	COG1960	acyl-CoA dehydrogenase activity
CG027_RS17465	COG0183	Belongs to the thiolase family
CG027_RS17470	COG1522	sequence-specific DNA binding
CG027_RS17475	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CG027_RS17495	COG1024	Enoyl-CoA hydratase
CG027_RS17510	COG0604	alcohol dehydrogenase
CG027_RS17530	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CG027_RS17540	COG1960	acyl-CoA dehydrogenase activity
CG027_RS17545	COG1960	acyl-CoA dehydrogenase activity
CG027_RS17550	COG0277	FAD linked oxidase domain protein
CG027_RS17560	COG3181	Tripartite tricarboxylate transporter family receptor
CG027_RS17585	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CG027_RS17595	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CG027_RS17600	COG3181	Tripartite tricarboxylate transporter family receptor
CG027_RS17605	COG1960	acyl-CoA dehydrogenase activity
CG027_RS17625	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CG027_RS17630	COG1024	Enoyl-CoA hydratase
CG027_RS17635	COG1960	acyl-CoA dehydrogenase activity
CG027_RS17655	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CG027_RS17660	COG0022	dehydrogenase e1 component
CG027_RS17665	COG1024	Enoyl-CoA hydratase
CG027_RS17670	COG0508	dehydrogenase complex catalyzes the overall conversion of
CG027_RS17690	COG0683	leucine binding
CG027_RS17695	COG0559	Belongs to the binding-protein-dependent transport system permease family
CG027_RS17700	COG0411	ABC transporter
CG027_RS17710	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CG027_RS17725	COG3181	Tripartite tricarboxylate transporter family receptor
CG027_RS17755	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CG027_RS17760	COG0793	Belongs to the peptidase S41A family
CG027_RS17765	COG4942	peptidase
CG027_RS17770	COG0588	phosphoglycerate mutase activity
CG027_RS17775	COG1054	Belongs to the UPF0176 family
CG027_RS17780	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CG027_RS17785	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CG027_RS17790	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CG027_RS17795	COG3181	Tripartite tricarboxylate transporter family receptor
CG027_RS17810	COG2226	methyltransferase
CG027_RS17815	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CG027_RS17830	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CG027_RS17835	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CG027_RS17860	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CG027_RS17885	COG1335	isochorismatase
CG027_RS17890	COG2309	aminopeptidase activity
CG027_RS17900	COG3473	Maleate cis-trans isomerase
CG027_RS17910	COG2068	MobA-Related Protein
CG027_RS17935	COG2204	response regulator
CG027_RS17940	COG5000	phosphorelay sensor kinase activity
CG027_RS17950	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CG027_RS17950	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CG027_RS17960	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
CG027_RS17995	COG0583	DNA-binding transcription factor activity
CG027_RS18015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CG027_RS18020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG027_RS18035	COG0758	DNA mediated transformation
CG027_RS18040	COG1522	sequence-specific DNA binding
CG027_RS18050	COG0242	peptide deformylase activity
CG027_RS18065	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CG027_RS18075	COG0546	phosphoglycolate phosphatase activity
CG027_RS18095	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CG027_RS18100	COG1942	4-Oxalocrotonate Tautomerase
CG027_RS18105	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CG027_RS18130	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CG027_RS18150	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CG027_RS18155	COG1024	Enoyl-CoA hydratase
CG027_RS18160	COG1414	Transcriptional regulator
CG027_RS18165	COG0318	PFAM AMP-dependent synthetase and ligase
CG027_RS18170	COG3181	Tripartite tricarboxylate transporter family receptor
CG027_RS18215	COG3422	double-strand break repair
CG027_RS18220	COG0330	HflC and HflK could
CG027_RS18230	COG0251	oxidation-reduction process
CG027_RS18280	COG3723	Recombinational DNA repair protein, rece pathway
CG027_RS18315	COG0582	viral genome integration into host DNA
CG027_RS18350	COG0706	membrane insertase activity
CG027_RS18355	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CG027_RS18360	COG0594	ribonuclease P activity
CG027_RS18365	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CG027_RS18370	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CG027_RS18385	COG1414	Transcriptional regulator
CG027_RS18390	COG0154	amidase activity
CG027_RS18405	COG1304	FMN binding
CG027_RS18455	COG0183	Belongs to the thiolase family
CG027_RS18460	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CG027_RS18475	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CG027_RS18480	COG3181	Tripartite tricarboxylate transporter family receptor
CG027_RS18490	COG2358	TRAP transporter, solute receptor (TAXI family
CG027_RS18500	COG1629	transport
CG027_RS18505	COG2922	Belongs to the Smg family
CG027_RS18530	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CG027_RS18535	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CG027_RS18540	COG1028	Short-chain dehydrogenase reductase Sdr
CG027_RS18545	COG1012	belongs to the aldehyde dehydrogenase family
CG027_RS18555	COG0028	Belongs to the TPP enzyme family
CG027_RS18560	COG1522	sequence-specific DNA binding
CG027_RS18565	COG3781	membrane
CG027_RS18575	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CG027_RS18595	COG4206	TonB-dependent receptor
CG027_RS18600	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CG027_RS18605	COG2022	thiamine diphosphate biosynthetic process
CG027_RS18610	COG0351	phosphomethylpyrimidine kinase
CG027_RS18615	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CG027_RS18630	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CG027_RS18640	COG0628	permease
CG027_RS18650	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CG027_RS18665	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CG027_RS18670	COG0049	tRNA binding
CG027_RS18675	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CG027_RS18680	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CG027_RS18685	COG0051	transcription antitermination factor activity, RNA binding
CG027_RS18690	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CG027_RS18695	COG0088	Forms part of the polypeptide exit tunnel
CG027_RS18700	COG0089	rRNA binding
CG027_RS18705	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CG027_RS18710	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CG027_RS18715	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CG027_RS18720	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CG027_RS18725	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CG027_RS18730	COG0255	Belongs to the universal ribosomal protein uL29 family
CG027_RS18735	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CG027_RS18755	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CG027_RS18760	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CG027_RS18765	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CG027_RS18770	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CG027_RS18775	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CG027_RS18780	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CG027_RS18785	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CG027_RS18790	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CG027_RS18795	COG1841	ribosomal large subunit assembly
CG027_RS18800	COG0200	Binds to the 23S rRNA
CG027_RS18805	COG0201	protein transport
CG027_RS18810	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CG027_RS18815	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CG027_RS18820	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CG027_RS18825	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CG027_RS18830	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CG027_RS18835	COG0202	RNA polymerase activity
CG027_RS18840	COG0203	ribosomal protein L17
CG027_RS18845	COG0537	adenosine 5'-monophosphoramidase activity
CG027_RS18850	COG1324	tolerance protein
CG027_RS18855	COG4232	protein-disulfide reductase activity
CG027_RS18870	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CG027_RS18880	COG1333	cytochrome c biogenesis protein
CG027_RS18885	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CG027_RS18900	COG1965	Belongs to the frataxin family
CG027_RS18910	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CG027_RS18915	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CG027_RS18920	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CG027_RS18935	COG2814	Major facilitator Superfamily
CG027_RS18940	COG0629	single-stranded DNA binding
CG027_RS18980	COG0402	S-adenosylhomocysteine deaminase activity
CG027_RS18990	COG0438	transferase activity, transferring glycosyl groups
CG027_RS19010	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CG027_RS19035	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CG027_RS19060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CG027_RS19065	COG1956	GAF domain-containing protein
CG027_RS19070	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CG027_RS19085	COG1652	LysM domain
CG027_RS19100	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CG027_RS19115	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CG027_RS19145	COG3181	Tripartite tricarboxylate transporter family receptor
CG027_RS19160	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CG027_RS19175	COG1024	Enoyl-CoA hydratase
CG027_RS19190	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CG027_RS19195	COG1309	transcriptional regulator
CG027_RS19200	COG2816	NAD+ diphosphatase activity
CG027_RS19205	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CG027_RS19290	COG2814	Major facilitator Superfamily
CG027_RS19295	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CG027_RS19315	COG1999	signal sequence binding
CG027_RS19320	COG0109	protoheme IX farnesyltransferase activity
CG027_RS19360	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CG027_RS19380	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CG027_RS19385	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CG027_RS19395	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CG027_RS19400	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CG027_RS19410	COG0069	glutamate synthase activity
CG027_RS19410	COG0070	glutamate synthase
CG027_RS19410	COG0067	glutamate synthase
CG027_RS19420	COG3047	cAMP biosynthetic process
CG027_RS19430	COG1127	ABC transporter
CG027_RS19435	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CG027_RS19440	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CG027_RS19445	COG2853	Lipoprotein
CG027_RS19460	COG0842	Transport permease protein
CG027_RS19470	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CG027_RS19475	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CG027_RS19480	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CG027_RS19485	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CG027_RS19490	COG0131	Imidazoleglycerol-phosphate dehydratase
CG027_RS19495	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CG027_RS19500	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CG027_RS19505	COG0107	imidazoleglycerol-phosphate synthase activity
CG027_RS19510	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CG027_RS19515	COG0140	phosphoribosyl-ATP diphosphatase activity
CG027_RS19520	COG0537	adenosine 5'-monophosphoramidase activity
CG027_RS19525	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CG027_RS19530	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CG027_RS19545	COG3181	Tripartite tricarboxylate transporter family receptor
CG027_RS19580	COG3702	type iv secretory pathway
CG027_RS19585	COG3451	type IV secretory pathway VirB4
CG027_RS19600	COG3736	Type IV secretory pathway, component VirB8
CG027_RS19605	COG3504	Conjugal transfer protein
CG027_RS19610	COG2948	multi-organism process
CG027_RS19615	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
CG027_RS19625	COG0697	spore germination
CG027_RS19645	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CG027_RS19650	COG0747	negative chemotaxis
CG027_RS19655	COG0601	transmembrane transport
CG027_RS19660	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CG027_RS19675	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CG027_RS19685	COG0494	nUDIX hydrolase
CG027_RS19730	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
CG027_RS19735	COG0237	dephospho-CoA kinase activity
CG027_RS19740	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CG027_RS19755	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CG027_RS19760	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CG027_RS19770	COG0477	Major facilitator Superfamily
CG027_RS19775	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CG027_RS19790	COG1126	abc transporter atp-binding protein
CG027_RS19795	COG0765	amino acid transport
CG027_RS19800	COG4597	amino acid ABC transporter
CG027_RS19805	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG027_RS19810	COG2884	Cell division ATP-binding protein ftsE
CG027_RS19815	COG2177	Part of the ABC transporter FtsEX involved in
CG027_RS19820	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CG027_RS19830	COG1194	a g-specific adenine glycosylase
CG027_RS19840	COG2226	methyltransferase
CG027_RS19850	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CG027_RS19855	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CG027_RS19870	COG1024	Enoyl-CoA hydratase
CG027_RS19890	COG1024	Enoyl-CoA hydratase
CG027_RS19895	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CG027_RS19910	COG0753	catalase activity
CG027_RS19915	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CG027_RS19920	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CG027_RS19930	COG2175	clavaminate synthase activity
CG027_RS19935	COG1473	amidohydrolase
CG027_RS19940	COG4608	Belongs to the ABC transporter superfamily
CG027_RS19945	COG0444	Belongs to the ABC transporter superfamily
CG027_RS19960	COG0747	negative chemotaxis
CG027_RS19965	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CG027_RS20000	COG0436	Aminotransferase
CG027_RS20005	COG1278	Cold shock