locus-tag	class	description
ABC53_RS00005	COG0445	tRNA wobble uridine modification
ABC53_RS00010	COG0357	Ribosomal RNA small subunit methyltransferase G
ABC53_RS00015	COG1192	Involved in chromosome partitioning
ABC53_RS00025	COG1475	DNA binding
ABC53_RS00030	COG0252	asparaginase activity
ABC53_RS00055	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ABC53_RS00065	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ABC53_RS00075	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ABC53_RS00080	COG0081	regulation of translation
ABC53_RS00085	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ABC53_RS00090	COG0222	ribosome binding
ABC53_RS00095	COG0085	RNA polymerase activity
ABC53_RS00100	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ABC53_RS00145	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC53_RS00170	COG1024	Enoyl-CoA hydratase
ABC53_RS00190	COG0752	glycyl-tRNA synthetase alpha subunit
ABC53_RS00195	COG0751	glycine-tRNA ligase activity
ABC53_RS00200	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ABC53_RS00205	COG0204	Acyl-transferase
ABC53_RS00220	COG0242	peptide deformylase activity
ABC53_RS00255	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ABC53_RS00260	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ABC53_RS00265	COG2813	Specifically methylates the guanine in position
ABC53_RS00265	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ABC53_RS00280	COG2223	nitrite transmembrane transporter activity
ABC53_RS00290	COG1794	racemase activity, acting on amino acids and derivatives
ABC53_RS00295	COG1126	abc transporter atp-binding protein
ABC53_RS00300	COG0765	amino acid transport
ABC53_RS00305	COG0765	amino acid transport
ABC53_RS00310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABC53_RS00375	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ABC53_RS00405	COG0326	Molecular chaperone. Has ATPase activity
ABC53_RS00410	COG0625	glutathione transferase activity
ABC53_RS00425	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ABC53_RS00430	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ABC53_RS00460	COG0438	transferase activity, transferring glycosyl groups
ABC53_RS00465	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ABC53_RS00470	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ABC53_RS00500	COG0859	PFAM glycosyl transferase family 9
ABC53_RS00515	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ABC53_RS00525	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ABC53_RS00530	COG1127	ABC transporter
ABC53_RS00550	COG1686	Belongs to the peptidase S11 family
ABC53_RS00560	COG2921	Belongs to the UPF0250 family
ABC53_RS00565	COG0321	lipoyl(octanoyl) transferase activity
ABC53_RS00570	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ABC53_RS00605	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ABC53_RS00615	COG0018	arginyl-trna synthetase
ABC53_RS00635	COG0395	ABC-type sugar transport system, permease component
ABC53_RS00640	COG1175	transmembrane transport
ABC53_RS00645	COG1653	transport
ABC53_RS00650	COG3842	ATPase activity
ABC53_RS00655	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ABC53_RS00665	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ABC53_RS00685	COG1609	Transcriptional regulator
ABC53_RS00695	COG0154	amidase activity
ABC53_RS00700	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ABC53_RS00710	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ABC53_RS00720	COG0583	DNA-binding transcription factor activity
ABC53_RS00735	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ABC53_RS00740	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ABC53_RS00755	COG1802	Transcriptional regulator
ABC53_RS00770	COG1024	Enoyl-CoA hydratase
ABC53_RS00780	COG3181	Tripartite tricarboxylate transporter family receptor
ABC53_RS00795	COG1984	allophanate hydrolase subunit 2
ABC53_RS00800	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ABC53_RS00810	COG0583	DNA-binding transcription factor activity
ABC53_RS00815	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ABC53_RS00825	COG5002	protein histidine kinase activity
ABC53_RS00835	COG5002	protein histidine kinase activity
ABC53_RS00840	COG0745	RESPONSE REGULATOR receiver
ABC53_RS00845	COG2226	methyltransferase
ABC53_RS00860	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ABC53_RS00880	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
ABC53_RS00890	COG0513	Belongs to the DEAD box helicase family
ABC53_RS00895	COG1280	lysine exporter protein (LysE YggA)
ABC53_RS00900	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ABC53_RS00935	COG1054	Belongs to the UPF0176 family
ABC53_RS00940	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ABC53_RS00940	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ABC53_RS00950	COG0489	protein tyrosine kinase activity
ABC53_RS00965	COG0717	Belongs to the dCTP deaminase family
ABC53_RS00995	COG2081	HI0933 family
ABC53_RS01005	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ABC53_RS01015	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ABC53_RS01020	COG0509	glycine decarboxylation via glycine cleavage system
ABC53_RS01025	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ABC53_RS01025	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ABC53_RS01065	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ABC53_RS01080	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ABC53_RS01090	COG1414	Transcriptional regulator
ABC53_RS01095	COG1028	Short-chain dehydrogenase reductase Sdr
ABC53_RS01100	COG2031	fatty acid transporter
ABC53_RS01105	COG1250	3-hydroxyacyl-CoA dehydrogenase
ABC53_RS01115	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ABC53_RS01120	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ABC53_RS01130	COG4257	antibiotic catabolic process
ABC53_RS01155	COG1012	belongs to the aldehyde dehydrogenase family
ABC53_RS01160	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ABC53_RS01165	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ABC53_RS01190	COG1028	Short-chain dehydrogenase reductase Sdr
ABC53_RS01200	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ABC53_RS01215	COG2188	Transcriptional regulator
ABC53_RS01220	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ABC53_RS01245	COG0617	tRNA 3'-terminal CCA addition
ABC53_RS01260	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ABC53_RS01265	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ABC53_RS01270	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ABC53_RS01275	COG0586	Pfam SNARE associated Golgi protein
ABC53_RS01280	COG0860	N-Acetylmuramoyl-L-alanine amidase
ABC53_RS01285	COG0802	atpase or kinase
ABC53_RS01290	COG0114	fumarate hydratase activity
ABC53_RS01300	COG3181	Tripartite tricarboxylate transporter family receptor
ABC53_RS01310	COG0405	Gamma-glutamyltransferase
ABC53_RS01315	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC53_RS01325	COG1960	acyl-CoA dehydrogenase activity
ABC53_RS01350	COG1294	oxidase, subunit
ABC53_RS01360	COG4988	ABC transporter
ABC53_RS01365	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ABC53_RS01370	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ABC53_RS01385	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ABC53_RS01415	COG2969	positive regulation of protein catabolic process
ABC53_RS01420	COG0625	glutathione transferase activity
ABC53_RS01425	COG2857	Cytochrome c1
ABC53_RS01430	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ABC53_RS01435	COG0723	plastoquinol--plastocyanin reductase activity
ABC53_RS01440	COG1970	mechanosensitive ion channel activity
ABC53_RS01445	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ABC53_RS01460	COG2808	Putative FMN-binding domain
ABC53_RS01465	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ABC53_RS01470	COG0747	negative chemotaxis
ABC53_RS01475	COG0657	acetylesterase activity
ABC53_RS01485	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ABC53_RS01490	COG2207	Transcriptional regulator
ABC53_RS01495	COG0129	dihydroxy-acid dehydratase activity
ABC53_RS01500	COG2814	Major facilitator Superfamily
ABC53_RS01505	COG0583	DNA-binding transcription factor activity
ABC53_RS01515	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
ABC53_RS01585	COG1024	Enoyl-CoA hydratase
ABC53_RS01590	COG1960	acyl-CoA dehydrogenase activity
ABC53_RS01615	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ABC53_RS01620	COG0352	thiamine-phosphate diphosphorylase activity
ABC53_RS01635	COG1678	Uncharacterized ACR, COG1678
ABC53_RS01640	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ABC53_RS01645	COG0540	Belongs to the ATCase OTCase family
ABC53_RS01660	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ABC53_RS01670	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ABC53_RS01705	COG1234	tRNA 3'-trailer cleavage
ABC53_RS01725	COG3064	Membrane
ABC53_RS01755	COG1683	Conserved Protein
ABC53_RS01760	COG1120	ATPase activity
ABC53_RS01765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ABC53_RS01770	COG4558	Periplasmic binding protein
ABC53_RS01775	COG3720	iron ion transport
ABC53_RS01785	COG3712	iron ion homeostasis
ABC53_RS01790	COG1595	DNA-templated transcription, initiation
ABC53_RS01825	COG1802	Transcriptional regulator
ABC53_RS01835	COG3069	C4-dicarboxylate transmembrane transporter activity
ABC53_RS01845	COG1012	belongs to the aldehyde dehydrogenase family
ABC53_RS01880	COG2860	membrane
ABC53_RS01885	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ABC53_RS01890	COG0708	Exodeoxyribonuclease III
ABC53_RS01895	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ABC53_RS01900	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ABC53_RS01905	COG0154	amidase activity
ABC53_RS01910	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ABC53_RS01915	COG1077	Cell shape determining protein MreB Mrl
ABC53_RS01920	COG1792	Involved in formation and maintenance of cell shape
ABC53_RS01930	COG0768	penicillin binding
ABC53_RS01935	COG0772	Belongs to the SEDS family
ABC53_RS01940	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ABC53_RS01945	COG0471	metal ion transport
ABC53_RS01950	COG1309	transcriptional regulator
ABC53_RS01960	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ABC53_RS01975	COG2823	Periplasmic or secreted lipoprotein
ABC53_RS01980	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ABC53_RS01995	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ABC53_RS02015	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC53_RS02025	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC53_RS02045	COG0492	ferredoxin-NADP+ reductase activity
ABC53_RS02055	COG3181	Tripartite tricarboxylate transporter family receptor
ABC53_RS02060	COG1024	Enoyl-CoA hydratase
ABC53_RS02060	COG1250	3-hydroxyacyl-CoA dehydrogenase
ABC53_RS02065	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC53_RS02070	COG0028	Belongs to the TPP enzyme family
ABC53_RS02095	COG3181	Tripartite tricarboxylate transporter family receptor
ABC53_RS02105	COG0697	spore germination
ABC53_RS02135	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ABC53_RS02140	COG0463	Glycosyl transferase, family 2
ABC53_RS02160	COG0786	glutamate:sodium symporter activity
ABC53_RS02170	COG2031	fatty acid transporter
ABC53_RS02185	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ABC53_RS02190	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ABC53_RS02200	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ABC53_RS02215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ABC53_RS02225	COG1285	pathogenesis
ABC53_RS02230	COG1253	flavin adenine dinucleotide binding
ABC53_RS02235	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC53_RS02240	COG1024	Enoyl-CoA hydratase
ABC53_RS02245	COG3181	Tripartite tricarboxylate transporter family receptor
ABC53_RS02250	COG0583	DNA-binding transcription factor activity
ABC53_RS02255	COG1960	acyl-CoA dehydrogenase activity
ABC53_RS02265	COG0183	Belongs to the thiolase family
ABC53_RS02285	COG0583	DNA-binding transcription factor activity
ABC53_RS02290	COG1278	Cold shock
ABC53_RS02300	COG1802	Transcriptional regulator
ABC53_RS02305	COG1012	belongs to the aldehyde dehydrogenase family
ABC53_RS02310	COG2031	fatty acid transporter
ABC53_RS02315	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ABC53_RS02315	COG1017	nitric oxide dioxygenase activity
ABC53_RS02320	COG0251	oxidation-reduction process
ABC53_RS02340	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC53_RS02350	COG0583	DNA-binding transcription factor activity
ABC53_RS02355	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC53_RS02365	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
ABC53_RS02370	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ABC53_RS02375	COG0546	phosphoglycolate phosphatase activity
ABC53_RS02385	COG1530	ribonuclease E activity
ABC53_RS02400	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
ABC53_RS02405	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ABC53_RS02410	COG0159	tryptophan synthase activity
ABC53_RS02415	COG0133	tryptophan synthase activity
ABC53_RS02425	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ABC53_RS02430	COG3228	Belongs to the MtfA family
ABC53_RS02440	COG0251	oxidation-reduction process
ABC53_RS02445	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ABC53_RS02450	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ABC53_RS02465	COG2878	Part of a membrane complex involved in electron transport
ABC53_RS02470	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ABC53_RS02505	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ABC53_RS02525	COG1268	BioY protein
ABC53_RS02530	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ABC53_RS02535	COG1122	ATPase activity
ABC53_RS02540	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ABC53_RS02555	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ABC53_RS02560	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ABC53_RS02570	COG1196	nuclear chromosome segregation
ABC53_RS02575	COG0477	Major facilitator Superfamily
ABC53_RS02580	COG1573	uracil-dna glycosylase
ABC53_RS02585	COG1214	PFAM Peptidase M22, glycoprotease
ABC53_RS02610	COG0450	alkyl hydroperoxide reductase
ABC53_RS02615	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ABC53_RS02625	COG2223	nitrite transmembrane transporter activity
ABC53_RS02635	COG2186	Transcriptional regulator
ABC53_RS02655	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ABC53_RS02665	COG0583	DNA-binding transcription factor activity
ABC53_RS02675	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ABC53_RS02680	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ABC53_RS02685	COG0137	argininosuccinate synthase activity
ABC53_RS02690	COG3158	transport of potassium into the cell
ABC53_RS02695	COG0642	Histidine kinase
ABC53_RS02725	COG0776	regulation of translation
ABC53_RS02730	COG3128	pkhd-type hydroxylase
ABC53_RS02740	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ABC53_RS02745	COG0557	exoribonuclease II activity
ABC53_RS02770	COG0679	Auxin Efflux Carrier
ABC53_RS02775	COG2391	methyltransferase activity
ABC53_RS02780	COG0069	glutamate synthase activity
ABC53_RS02790	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ABC53_RS02800	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
ABC53_RS02805	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ABC53_RS02840	COG3706	GGDEF domain
ABC53_RS02860	COG1053	succinate dehydrogenase
ABC53_RS02865	COG0583	DNA-binding transcription factor activity
ABC53_RS02875	COG1053	succinate dehydrogenase
ABC53_RS02895	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ABC53_RS02900	COG0459	protein refolding
ABC53_RS02905	COG3468	outer membrane autotransporter barrel domain protein
ABC53_RS02920	COG1252	NADH dehydrogenase
ABC53_RS02925	COG0284	orotidine-5'-phosphate decarboxylase activity
ABC53_RS02930	COG1546	Belongs to the CinA family
ABC53_RS02930	COG1058	Belongs to the CinA family
ABC53_RS02935	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ABC53_RS02945	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ABC53_RS02950	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ABC53_RS02985	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
ABC53_RS02990	COG3639	organic phosphonate transmembrane transporter activity
ABC53_RS02995	COG3639	organic phosphonate transmembrane transporter activity
ABC53_RS03015	COG0742	ribosomal rna small subunit methyltransferase
ABC53_RS03020	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ABC53_RS03025	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ABC53_RS03030	COG3135	benzoate transporter
ABC53_RS03045	COG0640	Transcriptional regulator
ABC53_RS03075	COG4172	Belongs to the ABC transporter superfamily
ABC53_RS03080	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABC53_RS03085	COG0601	transmembrane transport
ABC53_RS03095	COG0281	malic enzyme
ABC53_RS03095	COG0280	phosphate acetyltransferase
ABC53_RS03155	COG0583	DNA-binding transcription factor activity
ABC53_RS03165	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ABC53_RS03170	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
ABC53_RS03175	COG0167	dihydroorotate dehydrogenase activity
ABC53_RS03195	COG1414	Transcriptional regulator
ABC53_RS03200	COG1546	Belongs to the CinA family
ABC53_RS03200	COG1058	Belongs to the CinA family
ABC53_RS03220	COG0513	Belongs to the DEAD box helicase family
ABC53_RS03250	COG0429	hydrolase of the alpha beta-hydrolase fold
ABC53_RS03255	COG4783	chaperone-mediated protein folding
ABC53_RS03270	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ABC53_RS03295	COG0006	proline dipeptidase activity
ABC53_RS03305	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ABC53_RS03325	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ABC53_RS03330	COG0632	four-way junction helicase activity
ABC53_RS03345	COG2255	four-way junction helicase activity
ABC53_RS03350	COG0514	ATP-dependent DNA helicase (RecQ)
ABC53_RS03365	COG0288	reversible hydration of carbon dioxide
ABC53_RS03370	COG0154	amidase activity
ABC53_RS03380	COG4211	Belongs to the binding-protein-dependent transport system permease family
ABC53_RS03410	COG1464	Belongs to the NlpA lipoprotein family
ABC53_RS03555	COG1196	nuclear chromosome segregation
ABC53_RS03625	COG2135	peptidase activity
ABC53_RS03640	COG0494	nUDIX hydrolase
ABC53_RS03645	COG0442	prolyl-tRNA aminoacylation
ABC53_RS03650	COG0824	Thioesterase
ABC53_RS03655	COG0811	peptide transport
ABC53_RS03660	COG0848	biopolymer transport protein
ABC53_RS03670	COG0823	Involved in the tonB-independent uptake of proteins
ABC53_RS03685	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ABC53_RS03690	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
ABC53_RS03725	COG0700	Nucleoside recognition
ABC53_RS03730	COG0469	pyruvate kinase activity
ABC53_RS03735	COG1929	Belongs to the glycerate kinase type-1 family
ABC53_RS03740	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ABC53_RS03745	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ABC53_RS03750	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ABC53_RS03760	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ABC53_RS03770	COG2154	pterin-4-alpha-carbinolamine dehydratase
ABC53_RS03795	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ABC53_RS03800	COG0154	amidase activity
ABC53_RS03810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABC53_RS03815	COG0601	transmembrane transport
ABC53_RS03820	COG0747	negative chemotaxis
ABC53_RS03840	COG0019	diaminopimelate decarboxylase activity
ABC53_RS03855	COG2353	YceI-like domain
ABC53_RS03860	COG4774	siderophore transport
ABC53_RS03865	COG3712	iron ion homeostasis
ABC53_RS03905	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ABC53_RS03910	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ABC53_RS03915	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ABC53_RS03920	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ABC53_RS03930	COG0142	geranyltranstransferase activity
ABC53_RS03940	COG0583	DNA-binding transcription factor activity
ABC53_RS03950	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
ABC53_RS03955	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABC53_RS03970	COG2994	toxin metabolic process
ABC53_RS03980	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
ABC53_RS03985	COG2274	protein secretion by the type I secretion system
ABC53_RS03990	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ABC53_RS03995	COG1538	Outer membrane efflux protein
ABC53_RS04010	COG0765	amino acid transport
ABC53_RS04015	COG0765	amino acid transport
ABC53_RS04020	COG1126	abc transporter atp-binding protein
ABC53_RS04040	COG1028	Short-chain dehydrogenase reductase Sdr
ABC53_RS04050	COG1802	Transcriptional regulator
ABC53_RS04060	COG1802	Transcriptional regulator
ABC53_RS04070	COG0318	PFAM AMP-dependent synthetase and ligase
ABC53_RS04080	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABC53_RS04100	COG0028	Belongs to the TPP enzyme family
ABC53_RS04120	COG0308	aminopeptidase N
ABC53_RS04125	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ABC53_RS04135	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ABC53_RS04140	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ABC53_RS04145	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ABC53_RS04150	COG0560	Phosphoserine phosphatase
ABC53_RS04155	COG0583	DNA-binding transcription factor activity
ABC53_RS04160	COG3181	Tripartite tricarboxylate transporter family receptor
ABC53_RS04165	COG0028	Belongs to the TPP enzyme family
ABC53_RS04180	COG4774	siderophore transport
ABC53_RS04185	COG4774	siderophore transport
ABC53_RS04195	COG1007	ATP synthesis coupled electron transport
ABC53_RS04210	COG0713	ATP synthesis coupled electron transport
ABC53_RS04220	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABC53_RS04225	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ABC53_RS04230	COG1034	ATP synthesis coupled electron transport
ABC53_RS04240	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
ABC53_RS04245	COG0649	NAD binding
ABC53_RS04250	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABC53_RS04255	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABC53_RS04260	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABC53_RS04265	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ABC53_RS04295	COG0671	phosphoesterase, PA-phosphatase related
ABC53_RS04305	COG1597	lipid kinase activity
ABC53_RS04310	COG0583	DNA-binding transcription factor activity
ABC53_RS04315	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ABC53_RS04325	COG1733	regulation of RNA biosynthetic process
ABC53_RS04330	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ABC53_RS04335	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ABC53_RS04350	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
ABC53_RS04370	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABC53_RS04390	COG3608	succinylglutamate desuccinylase aspartoacylase
ABC53_RS04395	COG0626	cystathionine gamma-synthase activity
ABC53_RS04400	COG0583	DNA-binding transcription factor activity
ABC53_RS04435	COG3799	methylaspartate ammonia-lyase activity
ABC53_RS04445	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ABC53_RS04455	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ABC53_RS04460	COG0149	triose-phosphate isomerase activity
ABC53_RS04480	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ABC53_RS04495	COG1185	polyribonucleotide nucleotidyltransferase activity
ABC53_RS04500	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ABC53_RS04515	COG1183	phosphatidylcholine synthase activity
ABC53_RS04520	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ABC53_RS04525	COG0440	acetolactate synthase activity
ABC53_RS04530	COG0028	Belongs to the TPP enzyme family
ABC53_RS04545	COG5265	(ABC) transporter
ABC53_RS04550	COG0500	methyltransferase
ABC53_RS04570	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
ABC53_RS04590	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ABC53_RS04600	COG0511	ligase activity, forming carbon-carbon bonds
ABC53_RS04625	COG2188	Transcriptional regulator
ABC53_RS04630	COG0439	Biotin carboxylase
ABC53_RS04635	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ABC53_RS04680	COG5265	(ABC) transporter
ABC53_RS04690	COG0667	Aldo Keto reductase
ABC53_RS04705	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ABC53_RS04745	COG0583	DNA-binding transcription factor activity
ABC53_RS04770	COG2814	Major facilitator Superfamily
ABC53_RS04780	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ABC53_RS04795	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ABC53_RS04805	COG0287	Prephenate dehydrogenase
ABC53_RS04810	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ABC53_RS04815	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ABC53_RS04835	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ABC53_RS04840	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ABC53_RS04845	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ABC53_RS04850	COG1596	polysaccharide export
ABC53_RS04850	COG1555	photosystem II stabilization
ABC53_RS04865	COG2951	lytic endotransglycosylase activity
ABC53_RS04870	COG0123	including yeast histone deacetylase and acetoin utilization protein
ABC53_RS04885	COG1960	acyl-CoA dehydrogenase activity
ABC53_RS04890	COG0450	alkyl hydroperoxide reductase
ABC53_RS04905	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ABC53_RS04910	COG4208	sulfate ABC transporter
ABC53_RS04915	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ABC53_RS04945	COG0335	large ribosomal subunit rRNA binding
ABC53_RS04960	COG0667	Aldo Keto reductase
ABC53_RS04970	COG2814	Major facilitator Superfamily
ABC53_RS04975	COG3161	chorismate lyase activity
ABC53_RS04980	COG1187	pseudouridine synthase activity
ABC53_RS04990	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ABC53_RS05010	COG1999	signal sequence binding
ABC53_RS05015	COG0339	signal peptide processing
ABC53_RS05020	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ABC53_RS05025	COG4566	intracellular signal transduction
ABC53_RS05035	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ABC53_RS05040	COG0508	dehydrogenase complex catalyzes the overall conversion of
ABC53_RS05045	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ABC53_RS05050	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ABC53_RS05065	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ABC53_RS05070	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ABC53_RS05075	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ABC53_RS05080	COG0126	phosphoglycerate kinase activity
ABC53_RS05085	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ABC53_RS05090	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ABC53_RS05105	COG0625	glutathione transferase activity
ABC53_RS05140	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ABC53_RS05150	COG0521	Mo-molybdopterin cofactor biosynthetic process
ABC53_RS05160	COG0739	heme binding
ABC53_RS05170	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ABC53_RS05205	COG0745	RESPONSE REGULATOR receiver
ABC53_RS05220	COG0840	transmembrane signaling receptor activity
ABC53_RS05230	COG2201	protein-glutamate methylesterase activity
ABC53_RS05235	COG0745	RESPONSE REGULATOR receiver
ABC53_RS05240	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
ABC53_RS05265	COG0667	Aldo Keto reductase
ABC53_RS05275	COG4535	Mg2 and Co2 transporter CorC
ABC53_RS05280	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ABC53_RS05285	COG1702	phosphate starvation-inducible protein PhoH
ABC53_RS05290	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ABC53_RS05305	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ABC53_RS05310	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ABC53_RS05315	COG1862	Preprotein translocase
ABC53_RS05320	COG0343	queuine tRNA-ribosyltransferase activity
ABC53_RS05325	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ABC53_RS05330	COG2027	D-alanyl-D-alanine carboxypeptidase
ABC53_RS05335	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ABC53_RS05345	COG3468	outer membrane autotransporter barrel domain protein
ABC53_RS05355	COG3468	outer membrane autotransporter barrel domain protein
ABC53_RS05360	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ABC53_RS05360	COG1648	precorrin-2 dehydrogenase activity
ABC53_RS05385	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ABC53_RS05390	COG0741	lytic transglycosylase activity
ABC53_RS05395	COG0436	Aminotransferase
ABC53_RS05405	COG0280	phosphate acetyltransferase
ABC53_RS05405	COG0281	malic enzyme
ABC53_RS05415	COG2732	(Barnase) inhibitor
ABC53_RS05430	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ABC53_RS05455	COG0248	Ppx GppA phosphatase
ABC53_RS05465	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ABC53_RS05475	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ABC53_RS05480	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
ABC53_RS05485	COG1534	Rna-binding protein
ABC53_RS05515	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ABC53_RS05530	COG1295	ribonuclease BN
ABC53_RS05540	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ABC53_RS05545	COG0745	RESPONSE REGULATOR receiver
ABC53_RS05550	COG2205	protein histidine kinase activity
ABC53_RS05585	COG1022	Amp-dependent synthetase and ligase
ABC53_RS05600	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ABC53_RS05605	COG1028	Short-chain dehydrogenase reductase Sdr
ABC53_RS05615	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ABC53_RS05630	COG1136	(ABC) transporter
ABC53_RS05635	COG0084	hydrolase, TatD family'
ABC53_RS05665	COG2333	competence protein COMEC
ABC53_RS05665	COG0658	competence protein
ABC53_RS05675	COG0613	PHP domain protein
ABC53_RS05690	COG3539	Fimbrial protein
ABC53_RS05695	COG0280	phosphate acetyltransferase
ABC53_RS05695	COG0281	malic enzyme
ABC53_RS05705	COG1522	sequence-specific DNA binding
ABC53_RS05715	COG0567	Dehydrogenase, E1 component
ABC53_RS05720	COG0508	dehydrogenase complex catalyzes the overall conversion of
ABC53_RS05725	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ABC53_RS05730	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ABC53_RS05735	COG1028	Short-chain dehydrogenase reductase Sdr
ABC53_RS05740	COG0583	DNA-binding transcription factor activity
ABC53_RS05750	COG3181	Tripartite tricarboxylate transporter family receptor
ABC53_RS05775	COG0180	Tryptophanyl-tRNA synthetase
ABC53_RS05780	COG2183	response to ionizing radiation
ABC53_RS05785	COG1199	ATP-dependent helicase activity
ABC53_RS05795	COG0564	pseudouridine synthase activity
ABC53_RS05805	COG3243	poly(R)-hydroxyalkanoic acid synthase
ABC53_RS05810	COG1028	Short-chain dehydrogenase reductase Sdr
ABC53_RS05815	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
ABC53_RS05830	COG0672	)-iron permease
ABC53_RS05870	COG0583	DNA-binding transcription factor activity
ABC53_RS05880	COG2814	Major facilitator Superfamily
ABC53_RS05895	COG1619	proteins homologs of microcin C7 resistance protein MccF
ABC53_RS05910	COG2084	Dehydrogenase
ABC53_RS05915	COG3181	Tripartite tricarboxylate transporter family receptor
ABC53_RS05940	COG2988	succinylglutamate desuccinylase activity
ABC53_RS05965	COG0765	amino acid transport
ABC53_RS05970	COG0765	amino acid transport
ABC53_RS05975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABC53_RS06010	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ABC53_RS06015	COG1595	DNA-templated transcription, initiation
ABC53_RS06025	COG3530	Putative quorum-sensing-regulated virulence factor
ABC53_RS06030	COG0494	nUDIX hydrolase
ABC53_RS06045	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ABC53_RS06050	COG0542	response to heat
ABC53_RS06065	COG3468	outer membrane autotransporter barrel domain protein
ABC53_RS06070	COG3468	outer membrane autotransporter barrel domain protein
ABC53_RS06080	COG5441	Belongs to the UPF0261 family
ABC53_RS06085	COG5564	TIM-barrel signal transduction protein
ABC53_RS06100	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
ABC53_RS06115	COG1477	protein flavinylation
ABC53_RS06135	COG1131	(ABC) transporter
ABC53_RS06140	COG0842	Transport permease protein
ABC53_RS06150	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ABC53_RS06155	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
ABC53_RS06155	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
ABC53_RS06160	COG1562	ergosterol biosynthetic process
ABC53_RS06165	COG1562	ergosterol biosynthetic process
ABC53_RS06170	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ABC53_RS06175	COG1028	Short-chain dehydrogenase reductase Sdr
ABC53_RS06195	COG2304	oxidoreductase activity
ABC53_RS06215	COG0534	Mate efflux family protein
ABC53_RS06225	COG0254	rRNA binding
ABC53_RS06230	COG3483	tryptophan 2,3-dioxygenase activity
ABC53_RS06235	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
ABC53_RS06240	COG2003	Belongs to the UPF0758 family
ABC53_RS06245	COG1047	Peptidyl-prolyl cis-trans
ABC53_RS06250	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ABC53_RS06255	COG0625	glutathione transferase activity
ABC53_RS06275	COG0523	cobalamin synthesis protein
ABC53_RS06285	COG0583	DNA-binding transcription factor activity
ABC53_RS06295	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ABC53_RS06300	COG1187	pseudouridine synthase activity
ABC53_RS06305	COG0779	Required for maturation of 30S ribosomal subunits
ABC53_RS06310	COG2251	uridine kinase activity
ABC53_RS06310	COG0195	Participates in both transcription termination and antitermination
ABC53_RS06315	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ABC53_RS06320	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ABC53_RS06325	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ABC53_RS06345	COG1611	Belongs to the LOG family
ABC53_RS06360	COG0412	Dienelactone hydrolase
ABC53_RS06365	COG1283	sodium-dependent phosphate transmembrane transporter activity
ABC53_RS06370	COG1760	l-serine dehydratase
ABC53_RS06375	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ABC53_RS06380	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ABC53_RS06390	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ABC53_RS06415	COG2311	Membrane
ABC53_RS06425	COG0697	spore germination
ABC53_RS06440	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ABC53_RS06455	COG0559	Belongs to the binding-protein-dependent transport system permease family
ABC53_RS06470	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ABC53_RS06480	COG1653	transport
ABC53_RS06485	COG1175	transmembrane transport
ABC53_RS06490	COG0395	ABC-type sugar transport system, permease component
ABC53_RS06495	COG3842	ATPase activity
ABC53_RS06520	COG2363	Small membrane protein
ABC53_RS06535	COG1464	Belongs to the NlpA lipoprotein family
ABC53_RS06545	COG0688	phosphatidylethanolamine metabolic process
ABC53_RS06570	COG0625	glutathione transferase activity
ABC53_RS06575	COG0386	Belongs to the glutathione peroxidase family
ABC53_RS06595	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC53_RS06625	COG2259	Doxx family
ABC53_RS06640	COG0667	Aldo Keto reductase
ABC53_RS06670	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
ABC53_RS06690	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ABC53_RS06700	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ABC53_RS06740	COG0392	lysyltransferase activity
ABC53_RS06755	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ABC53_RS06760	COG3568	Endonuclease Exonuclease Phosphatase
ABC53_RS06770	COG1695	Transcriptional regulator
ABC53_RS06790	COG0583	DNA-binding transcription factor activity
ABC53_RS06805	COG1802	Transcriptional regulator
ABC53_RS06815	COG3181	Tripartite tricarboxylate transporter family receptor
ABC53_RS06825	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC53_RS06840	COG0066	3-isopropylmalate dehydratase activity
ABC53_RS06850	COG3181	Tripartite tricarboxylate transporter family receptor
ABC53_RS06855	COG4948	Mandelate Racemase Muconate Lactonizing
ABC53_RS06870	COG1126	abc transporter atp-binding protein
ABC53_RS06875	COG0765	amino acid transport
ABC53_RS06880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABC53_RS06900	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ABC53_RS06925	COG1815	bacterial-type flagellum-dependent cell motility
ABC53_RS06930	COG1558	bacterial-type flagellum-dependent cell motility
ABC53_RS06940	COG1749	Flagellar hook protein flgE
ABC53_RS06955	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
ABC53_RS06960	COG1706	bacterial-type flagellum-dependent cell motility
ABC53_RS06970	COG1256	bacterial-type flagellum assembly
ABC53_RS06980	COG0840	transmembrane signaling receptor activity
ABC53_RS06985	COG0840	transmembrane signaling receptor activity
ABC53_RS06990	COG0840	transmembrane signaling receptor activity
ABC53_RS07010	COG1338	Plays a role in the flagellum-specific transport system
ABC53_RS07030	COG1580	Controls the rotational direction of flagella during chemotaxis
ABC53_RS07055	COG1157	protein secretion by the type III secretion system
ABC53_RS07065	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ABC53_RS07075	COG1677	Flagellar hook-basal body complex protein FliE
ABC53_RS07085	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ABC53_RS07120	COG0285	dihydrofolate synthase activity
ABC53_RS07150	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
ABC53_RS07155	COG0024	Methionine aminopeptidase
ABC53_RS07160	COG0052	Belongs to the universal ribosomal protein uS2 family
ABC53_RS07165	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ABC53_RS07170	COG0528	UMP kinase activity
ABC53_RS07175	COG0233	cytoplasmic translational termination
ABC53_RS07180	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ABC53_RS07190	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ABC53_RS07195	COG0750	zinc metalloprotease
ABC53_RS07200	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ABC53_RS07205	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
ABC53_RS07210	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ABC53_RS07215	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ABC53_RS07225	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ABC53_RS07230	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ABC53_RS07235	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ABC53_RS07240	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
ABC53_RS07250	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ABC53_RS07250	COG0519	Catalyzes the synthesis of GMP from XMP
ABC53_RS07265	COG0330	HflC and HflK could
ABC53_RS07270	COG3706	GGDEF domain
ABC53_RS07275	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ABC53_RS07285	COG2867	negative regulation of translational initiation
ABC53_RS07295	COG1960	acyl-CoA dehydrogenase activity
ABC53_RS07300	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ABC53_RS07330	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ABC53_RS07335	COG0505	Belongs to the CarA family
ABC53_RS07340	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ABC53_RS07350	COG0406	alpha-ribazole phosphatase activity
ABC53_RS07360	COG3842	ATPase activity
ABC53_RS07380	COG5001	Diguanylate cyclase
ABC53_RS07385	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ABC53_RS07395	COG1763	Mo-molybdopterin cofactor biosynthetic process
ABC53_RS07400	COG0303	'Molybdopterin
ABC53_RS07405	COG0746	molybdenum cofactor guanylyltransferase activity
ABC53_RS07410	COG0489	protein tyrosine kinase activity
ABC53_RS07440	COG0243	molybdopterin cofactor binding
ABC53_RS07440	COG3383	formate dehydrogenase (NAD+) activity
ABC53_RS07445	COG0437	4 iron, 4 sulfur cluster binding
ABC53_RS07475	COG1122	ATPase activity
ABC53_RS07485	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ABC53_RS07490	COG0066	3-isopropylmalate dehydratase activity
ABC53_RS07495	COG0473	3-isopropylmalate dehydrogenase activity
ABC53_RS07500	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ABC53_RS07510	COG0101	tRNA pseudouridine synthase activity
ABC53_RS07515	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ABC53_RS07530	COG0135	phosphoribosylanthranilate isomerase activity
ABC53_RS07545	COG3022	response to hydroperoxide
ABC53_RS07555	COG1289	transmembrane transporter activity
ABC53_RS07575	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ABC53_RS07585	COG2197	response regulator
ABC53_RS07590	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ABC53_RS07595	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ABC53_RS07600	COG0189	ligase activity
ABC53_RS07610	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ABC53_RS07615	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ABC53_RS07625	COG1764	response to oxidative stress
ABC53_RS07630	COG2423	ornithine cyclodeaminase activity
ABC53_RS07640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABC53_RS07645	COG0765	amino acid transport
ABC53_RS07650	COG0765	amino acid transport
ABC53_RS07655	COG1126	abc transporter atp-binding protein
ABC53_RS07710	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ABC53_RS07720	COG2944	sequence-specific DNA binding
ABC53_RS07730	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ABC53_RS07735	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ABC53_RS07740	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ABC53_RS07745	COG0009	L-threonylcarbamoyladenylate synthase
ABC53_RS07750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABC53_RS07755	COG1414	Transcriptional regulator
ABC53_RS07770	COG0765	amino acid transport
ABC53_RS07775	COG1126	abc transporter atp-binding protein
ABC53_RS07780	COG0028	Belongs to the TPP enzyme family
ABC53_RS07795	COG0028	Belongs to the TPP enzyme family
ABC53_RS07800	COG0583	DNA-binding transcription factor activity
ABC53_RS07805	COG4974	Belongs to the 'phage' integrase family
ABC53_RS07810	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ABC53_RS07815	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
ABC53_RS07830	COG1686	Belongs to the peptidase S11 family
ABC53_RS07840	COG2814	Major facilitator Superfamily
ABC53_RS07850	COG1074	ATP-dependent DNA helicase activity
ABC53_RS07865	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ABC53_RS07870	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ABC53_RS07875	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ABC53_RS07900	COG2321	neutral zinc metallopeptidase
ABC53_RS07905	COG0009	L-threonylcarbamoyladenylate synthase
ABC53_RS07950	COG3360	Dodecin
ABC53_RS07955	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ABC53_RS07960	COG2850	peptidyl-arginine hydroxylation
ABC53_RS07965	COG3539	Fimbrial protein
ABC53_RS07970	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
ABC53_RS07975	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ABC53_RS07995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABC53_RS08000	COG0765	amino acid transport
ABC53_RS08005	COG1126	abc transporter atp-binding protein
ABC53_RS08010	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ABC53_RS08015	COG1758	RNA polymerase activity
ABC53_RS08020	COG0194	GDP metabolic process
ABC53_RS08025	COG3258	Cytochrome c
ABC53_RS08030	COG2863	cytochrome
ABC53_RS08035	COG1028	Short-chain dehydrogenase reductase Sdr
ABC53_RS08040	COG0791	NLP P60 protein
ABC53_RS08045	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ABC53_RS08065	COG1561	YicC-like family, N-terminal region
ABC53_RS08070	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ABC53_RS08085	COG0840	transmembrane signaling receptor activity
ABC53_RS08090	COG2199	diguanylate cyclase activity
ABC53_RS08090	COG2200	EAL domain
ABC53_RS08095	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ABC53_RS08105	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ABC53_RS08110	COG0174	glutamine synthetase
ABC53_RS08120	COG2204	response regulator
ABC53_RS08125	COG0583	DNA-binding transcription factor activity
ABC53_RS08130	COG1741	Belongs to the pirin family
ABC53_RS08135	COG1741	Belongs to the pirin family
ABC53_RS08145	COG3842	ATPase activity
ABC53_RS08150	COG1178	ABC-type Fe3 transport system permease component
ABC53_RS08155	COG1840	ABC-type Fe3 transport system, periplasmic component
ABC53_RS08165	COG0583	DNA-binding transcription factor activity
ABC53_RS08175	COG0656	L-ascorbic acid biosynthetic process
ABC53_RS08190	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ABC53_RS08195	COG0583	DNA-binding transcription factor activity
ABC53_RS08210	COG0783	Belongs to the Dps family
ABC53_RS08230	COG0463	Glycosyl transferase, family 2
ABC53_RS08250	COG0438	transferase activity, transferring glycosyl groups
ABC53_RS08265	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ABC53_RS08290	COG0300	oxidoreductase activity
ABC53_RS08335	COG0861	Integral membrane protein TerC family
ABC53_RS08340	COG1028	Short-chain dehydrogenase reductase Sdr
ABC53_RS08360	COG0714	Associated with various cellular activities
ABC53_RS08395	COG3119	arylsulfatase activity
ABC53_RS08420	COG2197	response regulator
ABC53_RS08430	COG2944	sequence-specific DNA binding
ABC53_RS08435	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
ABC53_RS08440	COG0625	glutathione transferase activity
ABC53_RS08470	COG0179	Fumarylacetoacetate (FAA) hydrolase
ABC53_RS08475	COG1028	Short-chain dehydrogenase reductase Sdr
ABC53_RS08520	COG0431	NADPH-dependent FMN reductase
ABC53_RS08555	COG1028	Short-chain dehydrogenase reductase Sdr
ABC53_RS08560	COG0583	DNA-binding transcription factor activity
ABC53_RS08575	COG3181	Tripartite tricarboxylate transporter family receptor
ABC53_RS08580	COG2111	Na H antiporter
ABC53_RS08580	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ABC53_RS08585	COG1006	Multisubunit Na H antiporter MnhC subunit
ABC53_RS08590	COG0651	ATP synthesis coupled electron transport
ABC53_RS08595	COG1863	multisubunit Na H antiporter MnhE subunit
ABC53_RS08600	COG2212	antiporter activity
ABC53_RS08625	COG0590	tRNA wobble adenosine to inosine editing
ABC53_RS08630	COG1619	proteins homologs of microcin C7 resistance protein MccF
ABC53_RS08635	COG1024	Enoyl-CoA hydratase
ABC53_RS08650	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ABC53_RS08655	COG0488	(ABC) transporter
ABC53_RS08690	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ABC53_RS08690	COG1017	nitric oxide dioxygenase activity
ABC53_RS08695	COG1959	2 iron, 2 sulfur cluster binding
ABC53_RS08700	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABC53_RS08720	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ABC53_RS08725	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ABC53_RS08730	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ABC53_RS08735	COG0084	hydrolase, TatD family'
ABC53_RS08750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABC53_RS08760	COG1126	abc transporter atp-binding protein
ABC53_RS08765	COG0010	Belongs to the arginase family
ABC53_RS08770	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ABC53_RS08775	COG1012	belongs to the aldehyde dehydrogenase family
ABC53_RS08785	COG0028	Belongs to the TPP enzyme family
ABC53_RS08795	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ABC53_RS08795	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ABC53_RS08805	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ABC53_RS08820	COG3189	MarR family transcriptional regulator
ABC53_RS08825	COG2010	Cytochrome c
ABC53_RS08850	COG4336	lyase activity
ABC53_RS08860	COG2205	protein histidine kinase activity
ABC53_RS08860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABC53_RS08865	COG2197	response regulator
ABC53_RS08870	COG3064	Membrane
ABC53_RS08870	COG3210	domain, Protein
ABC53_RS08870	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
ABC53_RS08880	COG3121	Chaperone
ABC53_RS08885	COG3188	usher protein
ABC53_RS08890	COG3539	Fimbrial protein
ABC53_RS08895	COG2831	hemolysin activation secretion protein
ABC53_RS08910	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ABC53_RS08935	COG0583	DNA-binding transcription factor activity
ABC53_RS08960	COG0668	transmembrane transport
ABC53_RS08980	COG0483	inositol monophosphate 1-phosphatase activity
ABC53_RS08985	COG1253	flavin adenine dinucleotide binding
ABC53_RS08990	COG1968	undecaprenyl-diphosphatase activity
ABC53_RS08995	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ABC53_RS09010	COG0215	cysteine-tRNA ligase activity
ABC53_RS09020	COG0825	malonyl-CoA metabolic process
ABC53_RS09030	COG0037	tRNA processing
ABC53_RS09035	COG0527	aspartate kinase activity
ABC53_RS09060	COG1250	3-hydroxyacyl-CoA dehydrogenase
ABC53_RS09065	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ABC53_RS09065	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ABC53_RS09080	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ABC53_RS09085	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
ABC53_RS09090	COG1028	Short-chain dehydrogenase reductase Sdr
ABC53_RS09100	COG0583	DNA-binding transcription factor activity
ABC53_RS09130	COG3842	ATPase activity
ABC53_RS09140	COG1902	pentaerythritol trinitrate reductase activity
ABC53_RS09140	COG0446	pyridine nucleotide-disulphide oxidoreductase
ABC53_RS09145	COG1414	Transcriptional regulator
ABC53_RS09150	COG1832	CoA-binding protein
ABC53_RS09160	COG0251	oxidation-reduction process
ABC53_RS09185	COG1902	pentaerythritol trinitrate reductase activity
ABC53_RS09195	COG1215	transferase activity, transferring glycosyl groups
ABC53_RS09200	COG0726	polysaccharide deacetylase
ABC53_RS09200	COG1649	PFAM Uncharacterised BCR, COG1649
ABC53_RS09220	COG1846	Transcriptional regulator
ABC53_RS09225	COG2197	response regulator
ABC53_RS09240	COG0166	Belongs to the GPI family
ABC53_RS09245	COG1045	serine acetyltransferase
ABC53_RS09255	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ABC53_RS09260	COG0483	inositol monophosphate 1-phosphatase activity
ABC53_RS09265	COG1012	belongs to the aldehyde dehydrogenase family
ABC53_RS09270	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ABC53_RS09285	COG0210	DNA helicase
ABC53_RS09290	COG0598	Magnesium transport protein CorA
ABC53_RS09300	COG0747	negative chemotaxis
ABC53_RS09305	COG0601	transmembrane transport
ABC53_RS09310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABC53_RS09315	COG4172	Belongs to the ABC transporter superfamily
ABC53_RS09320	COG1846	Transcriptional regulator
ABC53_RS09370	COG4964	Belongs to the GSP D family
ABC53_RS09410	COG2204	response regulator
ABC53_RS09425	COG1595	DNA-templated transcription, initiation
ABC53_RS09435	COG3474	cytochrome
ABC53_RS09440	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ABC53_RS09455	COG3384	dioxygenase
ABC53_RS09460	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ABC53_RS09485	COG2885	chlorophyll binding
ABC53_RS09520	COG0697	spore germination
ABC53_RS09525	COG0730	response to heat
ABC53_RS09545	COG0583	DNA-binding transcription factor activity
ABC53_RS09550	COG0427	acetyl-CoA hydrolase
ABC53_RS09605	COG1250	3-hydroxyacyl-CoA dehydrogenase
ABC53_RS09610	COG0154	amidase activity
ABC53_RS09620	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ABC53_RS09635	COG0495	leucyl-tRNA aminoacylation
ABC53_RS09640	COG2814	Major facilitator Superfamily
ABC53_RS09670	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ABC53_RS09675	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ABC53_RS09680	COG2814	Major facilitator Superfamily
ABC53_RS09685	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ABC53_RS09700	COG4176	ABC-type proline glycine betaine transport system permease component
ABC53_RS09710	COG1942	4-Oxalocrotonate Tautomerase
ABC53_RS09715	COG0183	Belongs to the thiolase family
ABC53_RS09725	COG1802	Transcriptional regulator
ABC53_RS09735	COG1024	Enoyl-CoA hydratase
ABC53_RS09740	COG0318	PFAM AMP-dependent synthetase and ligase
ABC53_RS09745	COG0318	PFAM AMP-dependent synthetase and ligase
ABC53_RS09755	COG2032	superoxide dismutase activity
ABC53_RS09770	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
ABC53_RS09795	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ABC53_RS09800	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ABC53_RS09810	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ABC53_RS09815	COG0736	holo-[acyl-carrier-protein] synthase activity
ABC53_RS09820	COG1472	Belongs to the glycosyl hydrolase 3 family
ABC53_RS09825	COG0322	excinuclease ABC activity
ABC53_RS09830	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ABC53_RS09845	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ABC53_RS09845	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ABC53_RS09850	COG2224	Isocitrate lyase
ABC53_RS09870	COG0559	Belongs to the binding-protein-dependent transport system permease family
ABC53_RS09880	COG4638	Rieske (2fe-2S)
ABC53_RS09890	COG1024	Enoyl-CoA hydratase
ABC53_RS09900	COG0633	Ferredoxin
ABC53_RS09905	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC53_RS09920	COG0183	Belongs to the thiolase family
ABC53_RS09965	COG2346	COG2346, Truncated hemoglobins
ABC53_RS10095	COG2207	Transcriptional regulator
ABC53_RS10140	COG1132	(ABC) transporter
ABC53_RS10165	COG0659	secondary active sulfate transmembrane transporter activity
ABC53_RS10195	COG2169	Transcriptional regulator
ABC53_RS10200	COG5507	3-demethylubiquinone-9 3-methyltransferase
ABC53_RS10205	COG0384	phenazine biosynthesis protein PhzF
ABC53_RS10210	COG0583	DNA-binding transcription factor activity
ABC53_RS10215	COG2733	membrane
ABC53_RS10230	COG1012	belongs to the aldehyde dehydrogenase family
ABC53_RS10235	COG3284	Transcriptional regulator
ABC53_RS10255	COG1380	Effector of murein hydrolase LrgA
ABC53_RS10260	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ABC53_RS10260	COG4106	trans-aconitate 2-methyltransferase activity
ABC53_RS10270	COG0156	8-amino-7-oxononanoate synthase activity
ABC53_RS10340	COG1131	(ABC) transporter
ABC53_RS10345	COG0842	Transport permease protein
ABC53_RS10350	COG0628	permease
ABC53_RS10385	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ABC53_RS10395	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ABC53_RS10400	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ABC53_RS10405	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ABC53_RS10410	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ABC53_RS10415	COG0330	HflC and HflK could
ABC53_RS10420	COG0330	HflC and HflK could
ABC53_RS10425	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ABC53_RS10430	COG1923	regulation of RNA biosynthetic process
ABC53_RS10435	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ABC53_RS10440	COG1160	GTP binding
ABC53_RS10445	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ABC53_RS10450	COG2976	Protein conserved in bacteria
ABC53_RS10455	COG0124	histidyl-tRNA synthetase
ABC53_RS10460	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ABC53_RS10470	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ABC53_RS10475	COG0105	UTP biosynthetic process
ABC53_RS10480	COG0525	valine-tRNA ligase activity
ABC53_RS10495	COG0642	Histidine kinase
ABC53_RS10515	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ABC53_RS10520	COG0336	Belongs to the RNA methyltransferase TrmD family
ABC53_RS10525	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ABC53_RS10530	COG0228	four-way junction DNA binding
ABC53_RS10540	COG0425	Belongs to the sulfur carrier protein TusA family
ABC53_RS10545	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ABC53_RS10590	COG0154	amidase activity
ABC53_RS10595	COG4172	Belongs to the ABC transporter superfamily
ABC53_RS10600	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABC53_RS10605	COG0601	transmembrane transport
ABC53_RS10610	COG0747	negative chemotaxis
ABC53_RS10640	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABC53_RS10650	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ABC53_RS10665	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ABC53_RS10670	COG3395	kinase activity
ABC53_RS10685	COG1024	Enoyl-CoA hydratase
ABC53_RS10705	COG0633	Ferredoxin
ABC53_RS10710	COG0443	Heat shock 70 kDa protein
ABC53_RS10715	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ABC53_RS10720	COG0316	Belongs to the HesB IscA family
ABC53_RS10725	COG0822	iron-sulfur transferase activity
ABC53_RS10730	COG1104	cysteine desulfurase activity
ABC53_RS10740	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ABC53_RS10745	COG0556	nucleotide-excision repair
ABC53_RS10755	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ABC53_RS10760	COG3468	outer membrane autotransporter barrel domain protein
ABC53_RS10790	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ABC53_RS10805	COG1960	acyl-CoA dehydrogenase activity
ABC53_RS10810	COG1028	Short-chain dehydrogenase reductase Sdr
ABC53_RS10815	COG0183	Belongs to the thiolase family
ABC53_RS10825	COG1024	Enoyl-CoA hydratase
ABC53_RS10840	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC53_RS10845	COG0583	DNA-binding transcription factor activity
ABC53_RS10850	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ABC53_RS10855	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ABC53_RS10860	COG0740	serine-type endopeptidase activity
ABC53_RS10865	COG0544	peptidyl-prolyl cis-trans isomerase activity
ABC53_RS10885	COG1278	Cold shock
ABC53_RS10920	COG2171	N-acyltransferase activity
ABC53_RS10925	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ABC53_RS10930	COG2890	protein-(glutamine-N5) methyltransferase activity
ABC53_RS10935	COG0488	(ABC) transporter
ABC53_RS10940	COG4771	TonB-dependent receptor
ABC53_RS10945	COG0210	DNA helicase
ABC53_RS10965	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ABC53_RS10970	COG0196	riboflavin kinase activity
ABC53_RS10975	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ABC53_RS10980	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ABC53_RS10985	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ABC53_RS10995	COG1522	sequence-specific DNA binding
ABC53_RS11020	COG2951	lytic endotransglycosylase activity
ABC53_RS11025	COG2833	Protein of unknown function (DUF455)
ABC53_RS11045	COG0189	ligase activity
ABC53_RS11045	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ABC53_RS11050	COG1181	Belongs to the D-alanine--D-alanine ligase family
ABC53_RS11050	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ABC53_RS11055	COG3237	CsbD-like
ABC53_RS11065	COG2823	Periplasmic or secreted lipoprotein
ABC53_RS11080	COG4181	ATPase activity
ABC53_RS11090	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ABC53_RS11095	COG0584	glycerophosphoryl diester phosphodiesterase
ABC53_RS11100	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ABC53_RS11110	COG0678	peroxiredoxin activity
ABC53_RS11110	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ABC53_RS11120	COG0789	Transcriptional regulator
ABC53_RS11125	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ABC53_RS11155	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ABC53_RS11160	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ABC53_RS11170	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ABC53_RS11175	COG2252	PERMEase
ABC53_RS11185	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ABC53_RS11215	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ABC53_RS11220	COG2358	TRAP transporter, solute receptor (TAXI family
ABC53_RS11250	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ABC53_RS11255	COG1366	Belongs to the anti-sigma-factor antagonist family
ABC53_RS11260	COG2172	sigma factor antagonist activity
ABC53_RS11265	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ABC53_RS11275	COG2770	Histidine kinase
ABC53_RS11275	COG2208	phosphoserine phosphatase activity
ABC53_RS11300	COG1595	DNA-templated transcription, initiation
ABC53_RS11315	COG4792	protein secretion
ABC53_RS11320	COG4791	protein targeting
ABC53_RS11325	COG4794	Type iii secretion
ABC53_RS11330	COG4790	Type iii secretion
ABC53_RS11365	COG4669	(LipO)protein
ABC53_RS11430	COG4789	Type iii secretion
ABC53_RS11460	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ABC53_RS11465	COG0840	transmembrane signaling receptor activity
ABC53_RS11470	COG2233	PERMEase
ABC53_RS11495	COG0492	ferredoxin-NADP+ reductase activity
ABC53_RS11500	COG1840	ABC-type Fe3 transport system, periplasmic component
ABC53_RS11505	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ABC53_RS11510	COG1178	ABC-type Fe3 transport system permease component
ABC53_RS11515	COG3842	ATPase activity
ABC53_RS11520	COG0583	DNA-binding transcription factor activity
ABC53_RS11540	COG0501	Belongs to the peptidase M48B family
ABC53_RS11550	COG0697	spore germination
ABC53_RS11560	COG1846	Transcriptional regulator
ABC53_RS11570	COG1566	PFAM secretion protein HlyD family protein
ABC53_RS11575	COG2814	Major facilitator Superfamily
ABC53_RS11580	COG0473	3-isopropylmalate dehydrogenase activity
ABC53_RS11590	COG0747	negative chemotaxis
ABC53_RS11600	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABC53_RS11615	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ABC53_RS11640	COG1012	belongs to the aldehyde dehydrogenase family
ABC53_RS11650	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ABC53_RS11655	COG1115	amino acid carrier protein
ABC53_RS11660	COG0433	COG0433 Predicted ATPase
ABC53_RS11665	COG0217	transcriptional regulatory protein
ABC53_RS11670	COG0151	Belongs to the GarS family
ABC53_RS11675	COG0408	coproporphyrinogen oxidase activity
ABC53_RS11680	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ABC53_RS11685	COG0799	negative regulation of ribosome biogenesis
ABC53_RS11690	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ABC53_RS11695	COG0424	maF-like protein
ABC53_RS11700	COG3468	outer membrane autotransporter barrel domain protein
ABC53_RS11740	COG1530	ribonuclease E activity
ABC53_RS11745	COG0077	Prephenate dehydratase
ABC53_RS11760	COG1132	(ABC) transporter
ABC53_RS11765	COG0859	PFAM glycosyl transferase family 9
ABC53_RS11790	COG2194	sulfuric ester hydrolase activity
ABC53_RS11795	COG0438	transferase activity, transferring glycosyl groups
ABC53_RS11800	COG0463	Glycosyl transferase, family 2
ABC53_RS11805	COG0726	polysaccharide deacetylase
ABC53_RS11810	COG0438	transferase activity, transferring glycosyl groups
ABC53_RS11825	COG1643	Atp-dependent helicase
ABC53_RS11830	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ABC53_RS11830	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ABC53_RS11835	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
ABC53_RS11845	COG0704	Plays a role in the regulation of phosphate uptake
ABC53_RS11850	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ABC53_RS11855	COG1960	acyl-CoA dehydrogenase activity
ABC53_RS11880	COG1177	transmembrane transport
ABC53_RS11885	COG1176	ABC-type spermidine putrescine transport system, permease component I
ABC53_RS11890	COG3842	ATPase activity
ABC53_RS11895	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ABC53_RS11910	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
ABC53_RS11915	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ABC53_RS11925	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ABC53_RS11925	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ABC53_RS11945	COG0372	Belongs to the citrate synthase family
ABC53_RS11950	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
ABC53_RS11955	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ABC53_RS11960	COG1053	succinate dehydrogenase
ABC53_RS11965	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ABC53_RS11970	COG2009	succinate dehydrogenase
ABC53_RS11975	COG2188	Transcriptional regulator
ABC53_RS11980	COG0039	L-malate dehydrogenase activity
ABC53_RS12010	COG1981	membrane
ABC53_RS12035	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ABC53_RS12045	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ABC53_RS12075	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ABC53_RS12080	COG0148	phosphopyruvate hydratase activity
ABC53_RS12090	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ABC53_RS12095	COG0504	CTP synthase activity
ABC53_RS12120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABC53_RS12130	COG0747	negative chemotaxis
ABC53_RS12135	COG4172	Belongs to the ABC transporter superfamily
ABC53_RS12140	COG1446	asparaginase
ABC53_RS12170	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ABC53_RS12185	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
ABC53_RS12190	COG0697	spore germination
ABC53_RS12195	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ABC53_RS12205	COG3193	protein, possibly involved in utilization of glycolate and propanediol
ABC53_RS12210	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ABC53_RS12215	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ABC53_RS12220	COG0791	NLP P60 protein
ABC53_RS12235	COG0583	DNA-binding transcription factor activity
ABC53_RS12250	COG0583	DNA-binding transcription factor activity
ABC53_RS12260	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ABC53_RS12275	COG0670	Belongs to the BI1 family
ABC53_RS12280	COG3181	Tripartite tricarboxylate transporter family receptor
ABC53_RS12290	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ABC53_RS12300	COG1381	Involved in DNA repair and RecF pathway recombination
ABC53_RS12305	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ABC53_RS12310	COG0571	ribonuclease III activity
ABC53_RS12315	COG0681	Belongs to the peptidase S26 family
ABC53_RS12320	COG0481	GTPase activity
ABC53_RS12325	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ABC53_RS12350	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ABC53_RS12355	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ABC53_RS12370	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ABC53_RS12375	COG0416	fatty acid biosynthetic process
ABC53_RS12380	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ABC53_RS12385	COG1399	metal-binding, possibly nucleic acid-binding protein
ABC53_RS12390	COG0424	maF-like protein
ABC53_RS12400	COG3023	N-Acetylmuramoyl-L-alanine amidase
ABC53_RS12405	COG1289	transmembrane transporter activity
ABC53_RS12415	COG3022	response to hydroperoxide
ABC53_RS12425	COG1028	Short-chain dehydrogenase reductase Sdr
ABC53_RS12440	COG3486	L-lysine 6-monooxygenase (NADPH) activity
ABC53_RS12470	COG2814	Major facilitator Superfamily
ABC53_RS12490	COG3706	GGDEF domain
ABC53_RS12515	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ABC53_RS12520	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ABC53_RS12525	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ABC53_RS12530	COG1674	ftsk spoiiie
ABC53_RS12535	COG0492	ferredoxin-NADP+ reductase activity
ABC53_RS12540	COG1193	negative regulation of DNA recombination
ABC53_RS12560	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ABC53_RS12575	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ABC53_RS12580	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
ABC53_RS12585	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
ABC53_RS12595	COG0745	RESPONSE REGULATOR receiver
ABC53_RS12640	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ABC53_RS12660	COG0612	Peptidase, M16
ABC53_RS12670	COG0443	Heat shock 70 kDa protein
ABC53_RS12680	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ABC53_RS12690	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ABC53_RS12695	COG1420	regulation of RNA biosynthetic process
ABC53_RS12700	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ABC53_RS12705	COG0497	DNA recombination
ABC53_RS12710	COG0735	belongs to the Fur family
ABC53_RS12715	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ABC53_RS12720	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ABC53_RS12725	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ABC53_RS12760	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ABC53_RS12760	COG0446	pyridine nucleotide-disulphide oxidoreductase
ABC53_RS12765	COG4311	Sarcosine oxidase, delta subunit
ABC53_RS12770	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABC53_RS12780	COG0583	DNA-binding transcription factor activity
ABC53_RS12790	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ABC53_RS12820	COG4964	Belongs to the GSP D family
ABC53_RS12880	COG0181	hydroxymethylbilane synthase activity
ABC53_RS12885	COG0861	Integral membrane protein TerC family
ABC53_RS12890	COG0861	Integral membrane protein TerC family
ABC53_RS12895	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ABC53_RS12900	COG0045	succinate-CoA ligase (ADP-forming) activity
ABC53_RS12910	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ABC53_RS12920	COG2137	regulation of response to DNA damage stimulus
ABC53_RS12925	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ABC53_RS12945	COG1024	Enoyl-CoA hydratase
ABC53_RS12945	COG1250	3-hydroxyacyl-CoA dehydrogenase
ABC53_RS12950	COG3842	ATPase activity
ABC53_RS12965	COG1028	Short-chain dehydrogenase reductase Sdr
ABC53_RS12985	COG0583	DNA-binding transcription factor activity
ABC53_RS12990	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC53_RS13000	COG2974	May be involved in recombination
ABC53_RS13005	COG0540	Belongs to the ATCase OTCase family
ABC53_RS13080	COG0776	regulation of translation
ABC53_RS13085	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ABC53_RS13085	COG0072	phenylalanine-tRNA ligase activity
ABC53_RS13090	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ABC53_RS13095	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ABC53_RS13100	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ABC53_RS13115	COG0756	dUTP diphosphatase activity
ABC53_RS13125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ABC53_RS13140	COG0500	methyltransferase
ABC53_RS13155	COG0586	Pfam SNARE associated Golgi protein
ABC53_RS13185	COG1609	Transcriptional regulator
ABC53_RS13190	COG4172	Belongs to the ABC transporter superfamily
ABC53_RS13195	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABC53_RS13200	COG0601	transmembrane transport
ABC53_RS13205	COG0747	negative chemotaxis
ABC53_RS13220	COG1280	lysine exporter protein (LysE YggA)
ABC53_RS13235	COG2814	Major facilitator Superfamily
ABC53_RS13265	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ABC53_RS13285	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ABC53_RS13325	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABC53_RS13330	COG1116	anion transmembrane transporter activity
ABC53_RS13340	COG1228	amidohydrolase
ABC53_RS13355	COG0477	Major facilitator Superfamily
ABC53_RS13365	COG3550	peptidyl-serine autophosphorylation
ABC53_RS13380	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ABC53_RS13380	COG0519	Catalyzes the synthesis of GMP from XMP
ABC53_RS13425	COG0420	3'-5' exonuclease activity
ABC53_RS13430	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABC53_RS13460	COG0395	ABC-type sugar transport system, permease component
ABC53_RS13470	COG3842	ATPase activity
ABC53_RS13500	COG3181	Tripartite tricarboxylate transporter family receptor
ABC53_RS13535	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ABC53_RS13560	COG0602	queuosine metabolic process
ABC53_RS13565	COG0720	synthase
ABC53_RS13570	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ABC53_RS13575	COG0235	Class ii aldolase
ABC53_RS13600	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
ABC53_RS13600	COG3210	domain, Protein
ABC53_RS13600	COG3064	Membrane
ABC53_RS13605	COG0047	phosphoribosylformylglycinamidine synthase activity
ABC53_RS13605	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ABC53_RS13610	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ABC53_RS13615	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ABC53_RS13615	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ABC53_RS13620	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ABC53_RS13640	COG3539	Fimbrial protein
ABC53_RS13650	COG2050	protein possibly involved in aromatic compounds catabolism
ABC53_RS13655	COG1024	Enoyl-CoA hydratase
ABC53_RS13660	COG1012	belongs to the aldehyde dehydrogenase family
ABC53_RS13670	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ABC53_RS13675	COG2151	metal-sulfur cluster biosynthetic enzyme
ABC53_RS13680	COG3396	Phenylacetate-CoA oxygenase
ABC53_RS13685	COG3460	Phenylacetate-CoA oxygenase
ABC53_RS13690	COG3396	Phenylacetate-CoA oxygenase
ABC53_RS13695	COG3327	negative regulation of DNA-templated transcription, initiation
ABC53_RS13705	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ABC53_RS13710	COG0501	Belongs to the peptidase M48B family
ABC53_RS13715	COG1162	GTPase activity
ABC53_RS13720	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABC53_RS13725	COG0601	transmembrane transport
ABC53_RS13730	COG0747	negative chemotaxis
ABC53_RS13775	COG0668	transmembrane transport
ABC53_RS13780	COG0165	Argininosuccinate lyase
ABC53_RS13800	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ABC53_RS13805	COG0303	'Molybdopterin
ABC53_RS13810	COG0521	Mo-molybdopterin cofactor biosynthetic process
ABC53_RS13825	COG0315	cyclic pyranopterin monophosphate synthase activity
ABC53_RS13835	COG0412	Dienelactone hydrolase
ABC53_RS13845	COG0678	peroxiredoxin activity
ABC53_RS13855	COG0697	spore germination
ABC53_RS13860	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ABC53_RS13885	COG0789	Transcriptional regulator
ABC53_RS13905	COG1028	Short-chain dehydrogenase reductase Sdr
ABC53_RS13915	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ABC53_RS13920	COG1845	cytochrome c oxidase, subunit III
ABC53_RS13925	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ABC53_RS13935	COG0477	Major facilitator Superfamily
ABC53_RS13965	COG3468	outer membrane autotransporter barrel domain protein
ABC53_RS13975	COG1309	transcriptional regulator
ABC53_RS13980	COG2271	Major facilitator Superfamily
ABC53_RS14015	COG0506	proline dehydrogenase activity
ABC53_RS14015	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ABC53_RS14015	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ABC53_RS14025	COG3008	intermembrane lipid transfer
ABC53_RS14025	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ABC53_RS14030	COG2995	paraquat-inducible protein a
ABC53_RS14035	COG0542	response to heat
ABC53_RS14040	COG4953	penicillin-binding protein 1C
ABC53_RS14050	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ABC53_RS14055	COG1278	Cold shock
ABC53_RS14065	COG0183	Belongs to the thiolase family
ABC53_RS14070	COG0038	chloride channel
ABC53_RS14075	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ABC53_RS14080	COG1570	exodeoxyribonuclease VII activity
ABC53_RS14090	COG0811	peptide transport
ABC53_RS14095	COG0848	biopolymer transport protein
ABC53_RS14100	COG1663	tetraacyldisaccharide 4'-kinase activity
ABC53_RS14105	COG2835	tetraacyldisaccharide 4'-kinase activity
ABC53_RS14110	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ABC53_RS14115	COG0563	adenylate kinase activity
ABC53_RS14125	COG0728	peptidoglycan biosynthetic process
ABC53_RS14135	COG0268	Binds directly to 16S ribosomal RNA
ABC53_RS14165	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ABC53_RS14190	COG0436	Aminotransferase
ABC53_RS14195	COG3737	Protein of unknown function (DUF498/DUF598)
ABC53_RS14200	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ABC53_RS14210	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ABC53_RS14220	COG0305	Participates in initiation and elongation during chromosome replication
ABC53_RS14230	COG0359	binds to the 23S rRNA
ABC53_RS14235	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ABC53_RS14240	COG2965	DNA replication, synthesis of RNA primer
ABC53_RS14245	COG0360	Binds together with S18 to 16S ribosomal RNA
ABC53_RS14250	COG1469	GTP cyclohydrolase I activity
ABC53_RS14255	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ABC53_RS14260	COG0142	geranyltranstransferase activity
ABC53_RS14265	COG1722	exodeoxyribonuclease VII activity
ABC53_RS14275	COG3181	Tripartite tricarboxylate transporter family receptor
ABC53_RS14295	COG2239	Acts as a magnesium transporter
ABC53_RS14305	COG2855	membrane
ABC53_RS14315	COG1473	amidohydrolase
ABC53_RS14320	COG0318	PFAM AMP-dependent synthetase and ligase
ABC53_RS14345	COG1501	Belongs to the glycosyl hydrolase 31 family
ABC53_RS14350	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ABC53_RS14355	COG2011	ABC-type metal ion transport system permease component
ABC53_RS14375	COG1454	alcohol dehydrogenase
ABC53_RS14405	COG2186	Transcriptional regulator
ABC53_RS14410	COG3181	Tripartite tricarboxylate transporter family receptor
ABC53_RS14430	COG1175	transmembrane transport
ABC53_RS14435	COG0395	ABC-type sugar transport system, permease component
ABC53_RS14440	COG3842	ATPase activity
ABC53_RS14445	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ABC53_RS14455	COG1653	transport
ABC53_RS14475	COG2818	Glycosylase
ABC53_RS14480	COG2982	Protein involved in outer membrane biogenesis
ABC53_RS14490	COG1309	transcriptional regulator
ABC53_RS14495	COG1028	Short-chain dehydrogenase reductase Sdr
ABC53_RS14555	COG0583	DNA-binding transcription factor activity
ABC53_RS14560	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ABC53_RS14565	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ABC53_RS14580	COG1028	Short-chain dehydrogenase reductase Sdr
ABC53_RS14585	COG0477	Major facilitator Superfamily
ABC53_RS14595	COG0583	DNA-binding transcription factor activity
ABC53_RS14600	COG1448	Aminotransferase
ABC53_RS14605	COG1418	mRNA catabolic process
ABC53_RS14630	COG1063	alcohol dehydrogenase
ABC53_RS14650	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABC53_RS14660	COG0318	PFAM AMP-dependent synthetase and ligase
ABC53_RS14670	COG1522	sequence-specific DNA binding
ABC53_RS14675	COG3181	Tripartite tricarboxylate transporter family receptor
ABC53_RS14680	COG0307	riboflavin synthase, alpha
ABC53_RS14685	COG0154	amidase activity
ABC53_RS14705	COG2807	transmembrane transport
ABC53_RS14710	COG0590	tRNA wobble adenosine to inosine editing
ABC53_RS14720	COG0583	DNA-binding transcription factor activity
ABC53_RS14735	COG1902	pentaerythritol trinitrate reductase activity
ABC53_RS14755	COG0559	Belongs to the binding-protein-dependent transport system permease family
ABC53_RS14760	COG0251	oxidation-reduction process
ABC53_RS14765	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ABC53_RS14775	COG1414	Transcriptional regulator
ABC53_RS14780	COG1028	Short-chain dehydrogenase reductase Sdr
ABC53_RS14795	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABC53_RS14810	COG1024	Enoyl-CoA hydratase
ABC53_RS14815	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC53_RS14820	COG0154	amidase activity
ABC53_RS14860	COG3909	cytochrome
ABC53_RS14865	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ABC53_RS14870	COG0625	glutathione transferase activity
ABC53_RS14875	COG0730	response to heat
ABC53_RS14880	COG0482	sulfurtransferase activity
ABC53_RS14885	COG0583	DNA-binding transcription factor activity
ABC53_RS14905	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ABC53_RS14930	COG2819	hydrolase of the alpha beta superfamily
ABC53_RS14935	COG0247	lactate metabolic process
ABC53_RS14940	COG0277	FAD linked oxidase domain protein
ABC53_RS14945	COG0277	FAD linked oxidase domain protein
ABC53_RS14950	COG0277	FAD linked oxidase domain protein
ABC53_RS14955	COG3064	Membrane
ABC53_RS14955	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
ABC53_RS14955	COG3210	domain, Protein
ABC53_RS14955	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
ABC53_RS14955	COG3210	domain, Protein
ABC53_RS14955	COG3064	Membrane
ABC53_RS14960	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ABC53_RS14965	COG0312	modulator of DNA gyrase
ABC53_RS15000	COG1666	GTP binding
ABC53_RS15045	COG3220	belongs to the UPF0276 family
ABC53_RS15065	COG0640	Transcriptional regulator
ABC53_RS15070	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ABC53_RS15075	COG1845	cytochrome c oxidase, subunit III
ABC53_RS15080	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ABC53_RS15090	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
ABC53_RS15125	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC53_RS15130	COG0583	DNA-binding transcription factor activity
ABC53_RS15160	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ABC53_RS15160	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ABC53_RS15175	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ABC53_RS15180	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ABC53_RS15190	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ABC53_RS15205	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
ABC53_RS15210	COG0316	Belongs to the HesB IscA family
ABC53_RS15220	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ABC53_RS15225	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ABC53_RS15230	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ABC53_RS15235	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ABC53_RS15240	COG0312	modulator of DNA gyrase
ABC53_RS15245	COG3028	Belongs to the UPF0307 family
ABC53_RS15260	COG1116	anion transmembrane transporter activity
ABC53_RS15265	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABC53_RS15270	COG1335	isochorismatase
ABC53_RS15275	COG0346	lactoylglutathione lyase activity
ABC53_RS15280	COG0513	Belongs to the DEAD box helicase family
ABC53_RS15285	COG3069	C4-dicarboxylate transmembrane transporter activity
ABC53_RS15290	COG1802	Transcriptional regulator
ABC53_RS15305	COG0045	succinate-CoA ligase (ADP-forming) activity
ABC53_RS15305	COG1042	CoA-binding domain protein
ABC53_RS15305	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ABC53_RS15310	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ABC53_RS15325	COG1522	sequence-specific DNA binding
ABC53_RS15360	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ABC53_RS15365	COG1696	Membrane protein involved in D-alanine export
ABC53_RS15390	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ABC53_RS15400	COG2264	protein methyltransferase activity
ABC53_RS15405	COG0439	Biotin carboxylase
ABC53_RS15410	COG0511	ligase activity, forming carbon-carbon bonds
ABC53_RS15415	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ABC53_RS15420	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ABC53_RS15425	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ABC53_RS15430	COG3150	esterase
ABC53_RS15435	COG0557	exoribonuclease II activity
ABC53_RS15445	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ABC53_RS15465	COG1522	sequence-specific DNA binding
ABC53_RS15470	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABC53_RS15475	COG1028	Short-chain dehydrogenase reductase Sdr
ABC53_RS15495	COG0653	protein targeting
ABC53_RS15500	COG0739	heme binding
ABC53_RS15510	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ABC53_RS15515	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ABC53_RS15525	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ABC53_RS15530	COG1181	Belongs to the D-alanine--D-alanine ligase family
ABC53_RS15535	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ABC53_RS15540	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ABC53_RS15550	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ABC53_RS15555	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ABC53_RS15560	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ABC53_RS15570	COG3116	cell division
ABC53_RS15575	COG0275	rRNA processing
ABC53_RS15580	COG2001	Belongs to the MraZ family
ABC53_RS15590	COG0488	(ABC) transporter
ABC53_RS15595	COG0418	dihydroorotase activity
ABC53_RS15600	COG1473	amidohydrolase
ABC53_RS15650	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ABC53_RS15655	COG4654	Cytochrome c, class I
ABC53_RS15660	COG0129	dihydroxy-acid dehydratase activity
ABC53_RS15665	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ABC53_RS15720	COG2084	Dehydrogenase
ABC53_RS15725	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ABC53_RS15745	COG2096	Adenosyltransferase
ABC53_RS15755	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ABC53_RS15760	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ABC53_RS15770	COG0523	cobalamin synthesis protein
ABC53_RS15775	COG0735	belongs to the Fur family
ABC53_RS15795	COG0803	Belongs to the bacterial solute-binding protein 9 family
ABC53_RS15805	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
ABC53_RS15815	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ABC53_RS15825	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ABC53_RS15830	COG1560	Kdo2-lipid A biosynthetic process
ABC53_RS15840	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ABC53_RS15855	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ABC53_RS15860	COG1950	PFAM Membrane protein of
ABC53_RS15875	COG0583	DNA-binding transcription factor activity
ABC53_RS15885	COG0477	Major facilitator Superfamily
ABC53_RS15900	COG0617	tRNA 3'-terminal CCA addition
ABC53_RS15910	COG0513	Belongs to the DEAD box helicase family
ABC53_RS15915	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ABC53_RS15930	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ABC53_RS15935	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
ABC53_RS15995	COG1280	lysine exporter protein (LysE YggA)
ABC53_RS16010	COG0405	Gamma-glutamyltransferase
ABC53_RS16020	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABC53_RS16050	COG1309	transcriptional regulator
ABC53_RS16060	COG3181	Tripartite tricarboxylate transporter family receptor
ABC53_RS16070	COG0745	RESPONSE REGULATOR receiver
ABC53_RS16130	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ABC53_RS16155	COG0582	viral genome integration into host DNA
ABC53_RS16160	COG0012	GTP binding
ABC53_RS16170	COG0193	aminoacyl-tRNA hydrolase activity
ABC53_RS16175	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ABC53_RS16180	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ABC53_RS16190	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ABC53_RS16195	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
ABC53_RS16205	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ABC53_RS16230	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
ABC53_RS16240	COG1368	sulfuric ester hydrolase activity
ABC53_RS16245	COG0642	Histidine kinase
ABC53_RS16250	COG0745	RESPONSE REGULATOR receiver
ABC53_RS16255	COG0277	FAD linked oxidase domain protein
ABC53_RS16270	COG0166	Belongs to the GPI family
ABC53_RS16275	COG0438	transferase activity, transferring glycosyl groups
ABC53_RS16280	COG0438	transferase activity, transferring glycosyl groups
ABC53_RS16295	COG0438	transferase activity, transferring glycosyl groups
ABC53_RS16310	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ABC53_RS16315	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ABC53_RS16320	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
ABC53_RS16330	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ABC53_RS16340	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ABC53_RS16345	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ABC53_RS16355	COG0747	negative chemotaxis
ABC53_RS16360	COG0601	transmembrane transport
ABC53_RS16365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABC53_RS16385	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ABC53_RS16390	COG0830	nickel cation binding
ABC53_RS16400	COG0804	urea catabolic process
ABC53_RS16405	COG0832	Belongs to the urease beta subunit family
ABC53_RS16415	COG0831	urea catabolic process
ABC53_RS16420	COG0829	nickel cation binding
ABC53_RS16430	COG0633	Ferredoxin
ABC53_RS16445	COG2188	Transcriptional regulator
ABC53_RS16470	COG2719	SpoVR family
ABC53_RS16475	COG2718	Belongs to the UPF0229 family
ABC53_RS16490	COG1028	Short-chain dehydrogenase reductase Sdr
ABC53_RS16495	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC53_RS16510	COG1960	acyl-CoA dehydrogenase activity
ABC53_RS16555	COG0183	Belongs to the thiolase family
ABC53_RS16560	COG2030	dehydratase
ABC53_RS16630	COG0328	RNA-DNA hybrid ribonuclease activity
ABC53_RS16635	COG2226	methyltransferase
ABC53_RS16640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ABC53_RS16645	COG1388	LysM domain
ABC53_RS16645	COG0741	lytic transglycosylase activity
ABC53_RS16665	COG2979	Protein of unknown function (DUF533)
ABC53_RS16700	COG1271	oxidase subunit
ABC53_RS16705	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ABC53_RS16710	COG0850	regulation of cytokinetic process
ABC53_RS16715	COG2894	cell division
ABC53_RS16720	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
ABC53_RS16740	COG0488	(ABC) transporter
ABC53_RS16755	COG0601	transmembrane transport
ABC53_RS16765	COG1215	transferase activity, transferring glycosyl groups
ABC53_RS16780	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ABC53_RS16790	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ABC53_RS16810	COG0318	PFAM AMP-dependent synthetase and ligase
ABC53_RS16815	COG2188	Transcriptional regulator
ABC53_RS16820	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ABC53_RS16825	COG2814	Major facilitator Superfamily
ABC53_RS16835	COG0259	pyridoxamine-phosphate oxidase activity
ABC53_RS16840	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ABC53_RS16855	COG0583	DNA-binding transcription factor activity
ABC53_RS16860	COG1960	acyl-CoA dehydrogenase activity
ABC53_RS16880	COG0134	indole-3-glycerol-phosphate synthase activity
ABC53_RS16885	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ABC53_RS16890	COG0512	Glutamine amidotransferase of anthranilate synthase
ABC53_RS16900	COG0546	phosphoglycolate phosphatase activity
ABC53_RS16905	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ABC53_RS16910	COG2967	ApaG domain
ABC53_RS16915	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ABC53_RS16920	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ABC53_RS16925	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ABC53_RS16930	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ABC53_RS16940	COG0037	tRNA processing
ABC53_RS16950	COG3634	alkyl hydroperoxide reductase activity
ABC53_RS16955	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ABC53_RS16960	COG1024	Enoyl-CoA hydratase
ABC53_RS16985	COG0356	it plays a direct role in the translocation of protons across the membrane
ABC53_RS16995	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ABC53_RS17000	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ABC53_RS17005	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ABC53_RS17010	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ABC53_RS17015	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ABC53_RS17020	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ABC53_RS17030	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ABC53_RS17035	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ABC53_RS17040	COG0210	DNA helicase
ABC53_RS17050	COG2195	Cleaves the N-terminal amino acid of tripeptides
ABC53_RS17060	COG4172	Belongs to the ABC transporter superfamily
ABC53_RS17065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABC53_RS17070	COG0601	transmembrane transport
ABC53_RS17090	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ABC53_RS17095	COG1024	Enoyl-CoA hydratase
ABC53_RS17100	COG1024	Enoyl-CoA hydratase
ABC53_RS17125	COG1250	3-hydroxyacyl-CoA dehydrogenase
ABC53_RS17155	COG2132	Multicopper oxidase
ABC53_RS17165	COG1024	Enoyl-CoA hydratase
ABC53_RS17165	COG1250	3-hydroxyacyl-CoA dehydrogenase
ABC53_RS17175	COG1414	Transcriptional regulator
ABC53_RS17185	COG0154	amidase activity
ABC53_RS17215	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ABC53_RS17220	COG3568	Endonuclease Exonuclease Phosphatase
ABC53_RS17225	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ABC53_RS17260	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ABC53_RS17270	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ABC53_RS17285	COG1137	ATPase activity
ABC53_RS17290	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ABC53_RS17300	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
ABC53_RS17305	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ABC53_RS17305	COG2010	Cytochrome c
ABC53_RS17315	COG1660	Displays ATPase and GTPase activities
ABC53_RS17320	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ABC53_RS17355	COG3181	Tripartite tricarboxylate transporter family receptor
ABC53_RS17365	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ABC53_RS17370	COG2890	protein-(glutamine-N5) methyltransferase activity
ABC53_RS17375	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ABC53_RS17380	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ABC53_RS17430	COG1960	acyl-CoA dehydrogenase activity
ABC53_RS17440	COG0183	Belongs to the thiolase family
ABC53_RS17445	COG1522	sequence-specific DNA binding
ABC53_RS17450	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ABC53_RS17470	COG1024	Enoyl-CoA hydratase
ABC53_RS17485	COG0604	alcohol dehydrogenase
ABC53_RS17505	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ABC53_RS17515	COG1960	acyl-CoA dehydrogenase activity
ABC53_RS17520	COG1960	acyl-CoA dehydrogenase activity
ABC53_RS17525	COG0277	FAD linked oxidase domain protein
ABC53_RS17535	COG3181	Tripartite tricarboxylate transporter family receptor
ABC53_RS17560	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ABC53_RS17570	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC53_RS17575	COG3181	Tripartite tricarboxylate transporter family receptor
ABC53_RS17580	COG1960	acyl-CoA dehydrogenase activity
ABC53_RS17600	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ABC53_RS17605	COG1024	Enoyl-CoA hydratase
ABC53_RS17610	COG1960	acyl-CoA dehydrogenase activity
ABC53_RS17630	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ABC53_RS17635	COG0022	dehydrogenase e1 component
ABC53_RS17640	COG1024	Enoyl-CoA hydratase
ABC53_RS17645	COG0508	dehydrogenase complex catalyzes the overall conversion of
ABC53_RS17665	COG0683	leucine binding
ABC53_RS17670	COG0559	Belongs to the binding-protein-dependent transport system permease family
ABC53_RS17675	COG0411	ABC transporter
ABC53_RS17685	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ABC53_RS17700	COG3181	Tripartite tricarboxylate transporter family receptor
ABC53_RS17730	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ABC53_RS17735	COG0793	Belongs to the peptidase S41A family
ABC53_RS17740	COG4942	peptidase
ABC53_RS17745	COG0588	phosphoglycerate mutase activity
ABC53_RS17750	COG1054	Belongs to the UPF0176 family
ABC53_RS17755	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ABC53_RS17760	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
ABC53_RS17765	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ABC53_RS17770	COG3181	Tripartite tricarboxylate transporter family receptor
ABC53_RS17785	COG2226	methyltransferase
ABC53_RS17790	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ABC53_RS17805	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABC53_RS17810	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ABC53_RS17835	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ABC53_RS17860	COG1335	isochorismatase
ABC53_RS17865	COG2309	aminopeptidase activity
ABC53_RS17870	COG0596	Alpha beta hydrolase
ABC53_RS17875	COG3473	Maleate cis-trans isomerase
ABC53_RS17885	COG2068	MobA-Related Protein
ABC53_RS17910	COG2204	response regulator
ABC53_RS17915	COG5000	phosphorelay sensor kinase activity
ABC53_RS17925	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ABC53_RS17925	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ABC53_RS17935	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
ABC53_RS17965	COG0583	DNA-binding transcription factor activity
ABC53_RS17980	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ABC53_RS17985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ABC53_RS17990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABC53_RS18005	COG0758	DNA mediated transformation
ABC53_RS18010	COG1522	sequence-specific DNA binding
ABC53_RS18020	COG0242	peptide deformylase activity
ABC53_RS18035	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ABC53_RS18045	COG0546	phosphoglycolate phosphatase activity
ABC53_RS18065	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ABC53_RS18070	COG1942	4-Oxalocrotonate Tautomerase
ABC53_RS18075	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABC53_RS18100	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ABC53_RS18120	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ABC53_RS18125	COG1024	Enoyl-CoA hydratase
ABC53_RS18130	COG1414	Transcriptional regulator
ABC53_RS18135	COG0318	PFAM AMP-dependent synthetase and ligase
ABC53_RS18140	COG3181	Tripartite tricarboxylate transporter family receptor
ABC53_RS18170	COG0583	DNA-binding transcription factor activity
ABC53_RS18185	COG3422	double-strand break repair
ABC53_RS18190	COG0330	HflC and HflK could
ABC53_RS18200	COG0251	oxidation-reduction process
ABC53_RS18245	COG3723	Recombinational DNA repair protein, rece pathway
ABC53_RS18280	COG0582	viral genome integration into host DNA
ABC53_RS18305	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ABC53_RS18315	COG0706	membrane insertase activity
ABC53_RS18320	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ABC53_RS18325	COG0594	ribonuclease P activity
ABC53_RS18330	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ABC53_RS18335	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ABC53_RS18350	COG1414	Transcriptional regulator
ABC53_RS18355	COG0154	amidase activity
ABC53_RS18370	COG1304	FMN binding
ABC53_RS18395	COG1960	acyl-CoA dehydrogenase activity
ABC53_RS18415	COG1960	acyl-CoA dehydrogenase activity
ABC53_RS18430	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ABC53_RS18445	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ABC53_RS18450	COG3181	Tripartite tricarboxylate transporter family receptor
ABC53_RS18460	COG2358	TRAP transporter, solute receptor (TAXI family
ABC53_RS18470	COG1629	transport
ABC53_RS18475	COG2922	Belongs to the Smg family
ABC53_RS18500	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ABC53_RS18505	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABC53_RS18510	COG1028	Short-chain dehydrogenase reductase Sdr
ABC53_RS18515	COG1012	belongs to the aldehyde dehydrogenase family
ABC53_RS18525	COG0028	Belongs to the TPP enzyme family
ABC53_RS18530	COG1522	sequence-specific DNA binding
ABC53_RS18535	COG3781	membrane
ABC53_RS18545	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ABC53_RS18565	COG4206	TonB-dependent receptor
ABC53_RS18570	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ABC53_RS18575	COG2022	thiamine diphosphate biosynthetic process
ABC53_RS18580	COG0351	phosphomethylpyrimidine kinase
ABC53_RS18585	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ABC53_RS18600	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ABC53_RS18610	COG0628	permease
ABC53_RS18620	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ABC53_RS18630	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ABC53_RS18635	COG0049	tRNA binding
ABC53_RS18640	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ABC53_RS18645	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ABC53_RS18650	COG0051	transcription antitermination factor activity, RNA binding
ABC53_RS18655	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ABC53_RS18660	COG0088	Forms part of the polypeptide exit tunnel
ABC53_RS18665	COG0089	rRNA binding
ABC53_RS18670	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ABC53_RS18675	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ABC53_RS18680	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ABC53_RS18685	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ABC53_RS18690	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ABC53_RS18695	COG0255	Belongs to the universal ribosomal protein uL29 family
ABC53_RS18700	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ABC53_RS18720	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ABC53_RS18725	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ABC53_RS18730	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ABC53_RS18735	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ABC53_RS18740	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ABC53_RS18745	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ABC53_RS18750	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ABC53_RS18755	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ABC53_RS18760	COG1841	ribosomal large subunit assembly
ABC53_RS18765	COG0200	Binds to the 23S rRNA
ABC53_RS18770	COG0201	protein transport
ABC53_RS18775	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ABC53_RS18780	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ABC53_RS18785	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ABC53_RS18790	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ABC53_RS18795	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ABC53_RS18800	COG0202	RNA polymerase activity
ABC53_RS18805	COG0203	ribosomal protein L17
ABC53_RS18810	COG0537	adenosine 5'-monophosphoramidase activity
ABC53_RS18815	COG1324	tolerance protein
ABC53_RS18820	COG4232	protein-disulfide reductase activity
ABC53_RS18835	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ABC53_RS18845	COG1333	cytochrome c biogenesis protein
ABC53_RS18850	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ABC53_RS18865	COG1965	Belongs to the frataxin family
ABC53_RS18875	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ABC53_RS18880	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ABC53_RS18885	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ABC53_RS18900	COG2814	Major facilitator Superfamily
ABC53_RS18905	COG0629	single-stranded DNA binding
ABC53_RS18945	COG0402	S-adenosylhomocysteine deaminase activity
ABC53_RS18955	COG0438	transferase activity, transferring glycosyl groups
ABC53_RS18975	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABC53_RS19000	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ABC53_RS19005	COG2186	Transcriptional regulator
ABC53_RS19025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ABC53_RS19030	COG1956	GAF domain-containing protein
ABC53_RS19035	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ABC53_RS19050	COG1652	LysM domain
ABC53_RS19065	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ABC53_RS19080	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ABC53_RS19110	COG3181	Tripartite tricarboxylate transporter family receptor
ABC53_RS19125	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABC53_RS19140	COG1024	Enoyl-CoA hydratase
ABC53_RS19155	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC53_RS19160	COG1309	transcriptional regulator
ABC53_RS19165	COG2816	NAD+ diphosphatase activity
ABC53_RS19170	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ABC53_RS19255	COG2814	Major facilitator Superfamily
ABC53_RS19260	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ABC53_RS19280	COG1999	signal sequence binding
ABC53_RS19285	COG0109	protoheme IX farnesyltransferase activity
ABC53_RS19325	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ABC53_RS19345	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ABC53_RS19350	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ABC53_RS19360	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
ABC53_RS19365	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
ABC53_RS19375	COG0070	glutamate synthase
ABC53_RS19375	COG0069	glutamate synthase activity
ABC53_RS19375	COG0067	glutamate synthase
ABC53_RS19385	COG3047	cAMP biosynthetic process
ABC53_RS19395	COG1127	ABC transporter
ABC53_RS19400	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ABC53_RS19405	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ABC53_RS19410	COG2853	Lipoprotein
ABC53_RS19420	COG1131	(ABC) transporter
ABC53_RS19425	COG0842	Transport permease protein
ABC53_RS19435	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ABC53_RS19440	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ABC53_RS19445	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ABC53_RS19450	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ABC53_RS19455	COG0131	Imidazoleglycerol-phosphate dehydratase
ABC53_RS19460	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ABC53_RS19465	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ABC53_RS19470	COG0107	imidazoleglycerol-phosphate synthase activity
ABC53_RS19475	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ABC53_RS19480	COG0140	phosphoribosyl-ATP diphosphatase activity
ABC53_RS19485	COG0537	adenosine 5'-monophosphoramidase activity
ABC53_RS19490	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ABC53_RS19495	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ABC53_RS19510	COG3181	Tripartite tricarboxylate transporter family receptor
ABC53_RS19545	COG3702	type iv secretory pathway
ABC53_RS19550	COG3451	type IV secretory pathway VirB4
ABC53_RS19565	COG3736	Type IV secretory pathway, component VirB8
ABC53_RS19570	COG3504	Conjugal transfer protein
ABC53_RS19575	COG2948	multi-organism process
ABC53_RS19580	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
ABC53_RS19590	COG0697	spore germination
ABC53_RS19610	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ABC53_RS19615	COG0747	negative chemotaxis
ABC53_RS19620	COG0601	transmembrane transport
ABC53_RS19625	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABC53_RS19630	COG0444	Belongs to the ABC transporter superfamily
ABC53_RS19640	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ABC53_RS19650	COG0494	nUDIX hydrolase
ABC53_RS19690	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
ABC53_RS19695	COG0237	dephospho-CoA kinase activity
ABC53_RS19700	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ABC53_RS19715	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ABC53_RS19720	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ABC53_RS19730	COG0477	Major facilitator Superfamily
ABC53_RS19735	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ABC53_RS19750	COG1126	abc transporter atp-binding protein
ABC53_RS19755	COG0765	amino acid transport
ABC53_RS19760	COG4597	amino acid ABC transporter
ABC53_RS19765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABC53_RS19770	COG2884	Cell division ATP-binding protein ftsE
ABC53_RS19775	COG2177	Part of the ABC transporter FtsEX involved in
ABC53_RS19780	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ABC53_RS19790	COG1194	a g-specific adenine glycosylase
ABC53_RS19800	COG2226	methyltransferase
ABC53_RS19810	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC53_RS19815	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC53_RS19830	COG1024	Enoyl-CoA hydratase
ABC53_RS19850	COG1024	Enoyl-CoA hydratase
ABC53_RS19855	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC53_RS19860	COG3181	Tripartite tricarboxylate transporter family receptor
ABC53_RS19870	COG0753	catalase activity
ABC53_RS19875	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABC53_RS19880	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ABC53_RS19890	COG2175	clavaminate synthase activity
ABC53_RS19895	COG1473	amidohydrolase
ABC53_RS19900	COG4608	Belongs to the ABC transporter superfamily
ABC53_RS19905	COG0444	Belongs to the ABC transporter superfamily
ABC53_RS19920	COG0747	negative chemotaxis
ABC53_RS19925	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ABC53_RS19960	COG0436	Aminotransferase
ABC53_RS19965	COG1278	Cold shock