locus-tag	class	description
BG535_RS00005	COG0445	tRNA wobble uridine modification
BG535_RS00010	COG0357	Ribosomal RNA small subunit methyltransferase G
BG535_RS00015	COG1192	Involved in chromosome partitioning
BG535_RS00025	COG1475	DNA binding
BG535_RS00050	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BG535_RS00060	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BG535_RS00070	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BG535_RS00075	COG0081	regulation of translation
BG535_RS00080	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BG535_RS00085	COG0222	ribosome binding
BG535_RS00090	COG0085	RNA polymerase activity
BG535_RS00095	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BG535_RS00135	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BG535_RS00160	COG1024	Enoyl-CoA hydratase
BG535_RS00180	COG0752	glycyl-tRNA synthetase alpha subunit
BG535_RS00185	COG0751	glycine-tRNA ligase activity
BG535_RS00190	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BG535_RS00195	COG0204	Acyl-transferase
BG535_RS00210	COG0242	peptide deformylase activity
BG535_RS00245	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BG535_RS00250	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BG535_RS00255	COG2813	Specifically methylates the guanine in position
BG535_RS00255	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BG535_RS00270	COG2223	nitrite transmembrane transporter activity
BG535_RS00280	COG1794	racemase activity, acting on amino acids and derivatives
BG535_RS00285	COG1126	abc transporter atp-binding protein
BG535_RS00290	COG0765	amino acid transport
BG535_RS00295	COG0765	amino acid transport
BG535_RS00300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BG535_RS00365	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BG535_RS00395	COG0326	Molecular chaperone. Has ATPase activity
BG535_RS00400	COG0625	glutathione transferase activity
BG535_RS00415	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BG535_RS00420	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BG535_RS00450	COG0438	transferase activity, transferring glycosyl groups
BG535_RS00455	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BG535_RS00460	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BG535_RS00490	COG0859	PFAM glycosyl transferase family 9
BG535_RS00505	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BG535_RS00515	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BG535_RS00520	COG1127	ABC transporter
BG535_RS00540	COG1686	Belongs to the peptidase S11 family
BG535_RS00550	COG2921	Belongs to the UPF0250 family
BG535_RS00555	COG0321	lipoyl(octanoyl) transferase activity
BG535_RS00560	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BG535_RS00595	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BG535_RS00605	COG0018	arginyl-trna synthetase
BG535_RS00625	COG0395	ABC-type sugar transport system, permease component
BG535_RS00630	COG1175	transmembrane transport
BG535_RS00635	COG1653	transport
BG535_RS00640	COG3842	ATPase activity
BG535_RS00645	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BG535_RS00655	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BG535_RS00675	COG1609	Transcriptional regulator
BG535_RS00685	COG0154	amidase activity
BG535_RS00690	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BG535_RS00700	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BG535_RS00710	COG0583	DNA-binding transcription factor activity
BG535_RS00725	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BG535_RS00730	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BG535_RS00745	COG1802	Transcriptional regulator
BG535_RS00760	COG1024	Enoyl-CoA hydratase
BG535_RS00775	COG3181	Tripartite tricarboxylate transporter family receptor
BG535_RS00790	COG1984	allophanate hydrolase subunit 2
BG535_RS00795	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BG535_RS00805	COG0583	DNA-binding transcription factor activity
BG535_RS00810	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BG535_RS00820	COG5002	protein histidine kinase activity
BG535_RS00830	COG5002	protein histidine kinase activity
BG535_RS00835	COG0745	RESPONSE REGULATOR receiver
BG535_RS00840	COG2226	methyltransferase
BG535_RS00855	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BG535_RS00875	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BG535_RS00885	COG0513	Belongs to the DEAD box helicase family
BG535_RS00890	COG1280	lysine exporter protein (LysE YggA)
BG535_RS00895	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BG535_RS00930	COG1054	Belongs to the UPF0176 family
BG535_RS00935	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BG535_RS00935	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BG535_RS00945	COG0489	protein tyrosine kinase activity
BG535_RS00960	COG0717	Belongs to the dCTP deaminase family
BG535_RS00990	COG2081	HI0933 family
BG535_RS01005	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BG535_RS01015	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BG535_RS01020	COG0509	glycine decarboxylation via glycine cleavage system
BG535_RS01025	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BG535_RS01025	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BG535_RS01065	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BG535_RS01080	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BG535_RS01090	COG1414	Transcriptional regulator
BG535_RS01095	COG1028	Short-chain dehydrogenase reductase Sdr
BG535_RS01100	COG2031	fatty acid transporter
BG535_RS01105	COG1250	3-hydroxyacyl-CoA dehydrogenase
BG535_RS01115	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BG535_RS01120	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BG535_RS01130	COG4257	antibiotic catabolic process
BG535_RS01155	COG1012	belongs to the aldehyde dehydrogenase family
BG535_RS01160	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BG535_RS01165	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BG535_RS01190	COG1028	Short-chain dehydrogenase reductase Sdr
BG535_RS01200	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BG535_RS01210	COG2188	Transcriptional regulator
BG535_RS01215	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BG535_RS01240	COG0617	tRNA 3'-terminal CCA addition
BG535_RS01255	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BG535_RS01260	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BG535_RS01265	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BG535_RS01270	COG0586	Pfam SNARE associated Golgi protein
BG535_RS01275	COG0860	N-Acetylmuramoyl-L-alanine amidase
BG535_RS01280	COG0802	atpase or kinase
BG535_RS01285	COG0114	fumarate hydratase activity
BG535_RS01295	COG3181	Tripartite tricarboxylate transporter family receptor
BG535_RS01305	COG0405	Gamma-glutamyltransferase
BG535_RS01310	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BG535_RS01320	COG1960	acyl-CoA dehydrogenase activity
BG535_RS01345	COG1294	oxidase, subunit
BG535_RS01355	COG4988	ABC transporter
BG535_RS01360	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BG535_RS01380	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BG535_RS01410	COG2969	positive regulation of protein catabolic process
BG535_RS01415	COG0625	glutathione transferase activity
BG535_RS01420	COG2857	Cytochrome c1
BG535_RS01425	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BG535_RS01430	COG0723	plastoquinol--plastocyanin reductase activity
BG535_RS01435	COG1970	mechanosensitive ion channel activity
BG535_RS01440	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BG535_RS01455	COG2808	Putative FMN-binding domain
BG535_RS01460	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BG535_RS01465	COG0747	negative chemotaxis
BG535_RS01470	COG0657	acetylesterase activity
BG535_RS01480	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BG535_RS01485	COG2207	Transcriptional regulator
BG535_RS01490	COG0129	dihydroxy-acid dehydratase activity
BG535_RS01495	COG2814	Major facilitator Superfamily
BG535_RS01500	COG0583	DNA-binding transcription factor activity
BG535_RS01510	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
BG535_RS01580	COG1024	Enoyl-CoA hydratase
BG535_RS01585	COG1960	acyl-CoA dehydrogenase activity
BG535_RS01610	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BG535_RS01615	COG0352	thiamine-phosphate diphosphorylase activity
BG535_RS01620	COG0351	phosphomethylpyrimidine kinase
BG535_RS01630	COG1678	Uncharacterized ACR, COG1678
BG535_RS01635	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BG535_RS01640	COG0540	Belongs to the ATCase OTCase family
BG535_RS01655	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BG535_RS01665	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BG535_RS01700	COG1234	tRNA 3'-trailer cleavage
BG535_RS01710	COG0583	DNA-binding transcription factor activity
BG535_RS01720	COG3064	Membrane
BG535_RS01750	COG1683	Conserved Protein
BG535_RS01755	COG1120	ATPase activity
BG535_RS01760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BG535_RS01765	COG4558	Periplasmic binding protein
BG535_RS01770	COG3720	iron ion transport
BG535_RS01780	COG3712	iron ion homeostasis
BG535_RS01785	COG1595	DNA-templated transcription, initiation
BG535_RS01820	COG1802	Transcriptional regulator
BG535_RS01830	COG3069	C4-dicarboxylate transmembrane transporter activity
BG535_RS01840	COG1012	belongs to the aldehyde dehydrogenase family
BG535_RS01875	COG2860	membrane
BG535_RS01880	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BG535_RS01885	COG0708	Exodeoxyribonuclease III
BG535_RS01890	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BG535_RS01895	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BG535_RS01900	COG0154	amidase activity
BG535_RS01905	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BG535_RS01910	COG1077	Cell shape determining protein MreB Mrl
BG535_RS01915	COG1792	Involved in formation and maintenance of cell shape
BG535_RS01925	COG0768	penicillin binding
BG535_RS01930	COG0772	Belongs to the SEDS family
BG535_RS01935	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BG535_RS01940	COG0471	metal ion transport
BG535_RS01945	COG1309	transcriptional regulator
BG535_RS01955	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BG535_RS01970	COG2823	Periplasmic or secreted lipoprotein
BG535_RS01975	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BG535_RS01990	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BG535_RS02010	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BG535_RS02020	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BG535_RS02040	COG0492	ferredoxin-NADP+ reductase activity
BG535_RS02050	COG3181	Tripartite tricarboxylate transporter family receptor
BG535_RS02055	COG1024	Enoyl-CoA hydratase
BG535_RS02055	COG1250	3-hydroxyacyl-CoA dehydrogenase
BG535_RS02060	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BG535_RS02065	COG0028	Belongs to the TPP enzyme family
BG535_RS02090	COG3181	Tripartite tricarboxylate transporter family receptor
BG535_RS02100	COG0697	spore germination
BG535_RS02130	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BG535_RS02135	COG0463	Glycosyl transferase, family 2
BG535_RS02150	COG0786	glutamate:sodium symporter activity
BG535_RS02160	COG2031	fatty acid transporter
BG535_RS02175	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BG535_RS02180	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BG535_RS02190	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BG535_RS02205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BG535_RS02215	COG1285	pathogenesis
BG535_RS02220	COG1253	flavin adenine dinucleotide binding
BG535_RS02225	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BG535_RS02230	COG1024	Enoyl-CoA hydratase
BG535_RS02235	COG3181	Tripartite tricarboxylate transporter family receptor
BG535_RS02240	COG0583	DNA-binding transcription factor activity
BG535_RS02245	COG1960	acyl-CoA dehydrogenase activity
BG535_RS02255	COG0183	Belongs to the thiolase family
BG535_RS02275	COG0583	DNA-binding transcription factor activity
BG535_RS02280	COG1278	Cold shock
BG535_RS02290	COG1802	Transcriptional regulator
BG535_RS02295	COG1012	belongs to the aldehyde dehydrogenase family
BG535_RS02300	COG2031	fatty acid transporter
BG535_RS02305	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BG535_RS02305	COG1017	nitric oxide dioxygenase activity
BG535_RS02310	COG0251	oxidation-reduction process
BG535_RS02330	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BG535_RS02340	COG0583	DNA-binding transcription factor activity
BG535_RS02345	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BG535_RS02355	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
BG535_RS02360	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BG535_RS02365	COG0546	phosphoglycolate phosphatase activity
BG535_RS02375	COG1530	ribonuclease E activity
BG535_RS02390	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BG535_RS02395	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BG535_RS02400	COG0159	tryptophan synthase activity
BG535_RS02405	COG0133	tryptophan synthase activity
BG535_RS02415	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BG535_RS02420	COG3228	Belongs to the MtfA family
BG535_RS02430	COG0251	oxidation-reduction process
BG535_RS02435	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BG535_RS02440	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BG535_RS02455	COG2878	Part of a membrane complex involved in electron transport
BG535_RS02460	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BG535_RS02495	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BG535_RS02515	COG1268	BioY protein
BG535_RS02520	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BG535_RS02525	COG1122	ATPase activity
BG535_RS02530	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BG535_RS02545	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BG535_RS02550	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BG535_RS02560	COG1196	nuclear chromosome segregation
BG535_RS02565	COG0477	Major facilitator Superfamily
BG535_RS02570	COG1573	uracil-dna glycosylase
BG535_RS02575	COG1214	PFAM Peptidase M22, glycoprotease
BG535_RS02595	COG0450	alkyl hydroperoxide reductase
BG535_RS02600	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BG535_RS02610	COG2223	nitrite transmembrane transporter activity
BG535_RS02620	COG2186	Transcriptional regulator
BG535_RS02640	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BG535_RS02650	COG0583	DNA-binding transcription factor activity
BG535_RS02660	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BG535_RS02665	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BG535_RS02670	COG0137	argininosuccinate synthase activity
BG535_RS02675	COG3158	transport of potassium into the cell
BG535_RS02680	COG0642	Histidine kinase
BG535_RS02710	COG0776	regulation of translation
BG535_RS02715	COG3128	pkhd-type hydroxylase
BG535_RS02725	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BG535_RS02730	COG0557	exoribonuclease II activity
BG535_RS02755	COG0679	Auxin Efflux Carrier
BG535_RS02760	COG2391	methyltransferase activity
BG535_RS02765	COG0069	glutamate synthase activity
BG535_RS02775	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BG535_RS02785	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
BG535_RS02790	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BG535_RS02825	COG3706	GGDEF domain
BG535_RS02845	COG1053	succinate dehydrogenase
BG535_RS02850	COG0583	DNA-binding transcription factor activity
BG535_RS02860	COG1053	succinate dehydrogenase
BG535_RS02880	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BG535_RS02885	COG0459	protein refolding
BG535_RS02890	COG3468	outer membrane autotransporter barrel domain protein
BG535_RS02905	COG1252	NADH dehydrogenase
BG535_RS02910	COG0284	orotidine-5'-phosphate decarboxylase activity
BG535_RS02915	COG1058	Belongs to the CinA family
BG535_RS02915	COG1546	Belongs to the CinA family
BG535_RS02920	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BG535_RS02930	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BG535_RS02935	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BG535_RS02970	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BG535_RS02975	COG3639	organic phosphonate transmembrane transporter activity
BG535_RS02980	COG3639	organic phosphonate transmembrane transporter activity
BG535_RS03000	COG0742	ribosomal rna small subunit methyltransferase
BG535_RS03005	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BG535_RS03010	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BG535_RS03015	COG3135	benzoate transporter
BG535_RS03030	COG0640	Transcriptional regulator
BG535_RS03060	COG4172	Belongs to the ABC transporter superfamily
BG535_RS03065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BG535_RS03070	COG0601	transmembrane transport
BG535_RS03080	COG0281	malic enzyme
BG535_RS03080	COG0280	phosphate acetyltransferase
BG535_RS03140	COG0583	DNA-binding transcription factor activity
BG535_RS03150	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BG535_RS03155	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BG535_RS03160	COG0167	dihydroorotate dehydrogenase activity
BG535_RS03180	COG1414	Transcriptional regulator
BG535_RS03185	COG1546	Belongs to the CinA family
BG535_RS03185	COG1058	Belongs to the CinA family
BG535_RS03205	COG0513	Belongs to the DEAD box helicase family
BG535_RS03235	COG0429	hydrolase of the alpha beta-hydrolase fold
BG535_RS03240	COG4783	chaperone-mediated protein folding
BG535_RS03255	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BG535_RS03280	COG0006	proline dipeptidase activity
BG535_RS03290	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BG535_RS03310	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BG535_RS03315	COG0632	four-way junction helicase activity
BG535_RS03330	COG2255	four-way junction helicase activity
BG535_RS03335	COG0514	ATP-dependent DNA helicase (RecQ)
BG535_RS03350	COG0288	reversible hydration of carbon dioxide
BG535_RS03355	COG0154	amidase activity
BG535_RS03365	COG4211	Belongs to the binding-protein-dependent transport system permease family
BG535_RS03395	COG1464	Belongs to the NlpA lipoprotein family
BG535_RS03540	COG1196	nuclear chromosome segregation
BG535_RS03610	COG2135	peptidase activity
BG535_RS03625	COG0494	nUDIX hydrolase
BG535_RS03630	COG0442	prolyl-tRNA aminoacylation
BG535_RS03635	COG0824	Thioesterase
BG535_RS03640	COG0811	peptide transport
BG535_RS03645	COG0848	biopolymer transport protein
BG535_RS03655	COG0823	Involved in the tonB-independent uptake of proteins
BG535_RS03670	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BG535_RS03675	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BG535_RS03710	COG0700	Nucleoside recognition
BG535_RS03715	COG0469	pyruvate kinase activity
BG535_RS03720	COG1929	Belongs to the glycerate kinase type-1 family
BG535_RS03725	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BG535_RS03730	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BG535_RS03735	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BG535_RS03745	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BG535_RS03755	COG2154	pterin-4-alpha-carbinolamine dehydratase
BG535_RS03780	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BG535_RS03785	COG0154	amidase activity
BG535_RS03795	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BG535_RS03800	COG0601	transmembrane transport
BG535_RS03805	COG0747	negative chemotaxis
BG535_RS03825	COG0019	diaminopimelate decarboxylase activity
BG535_RS03840	COG2353	YceI-like domain
BG535_RS03845	COG4774	siderophore transport
BG535_RS03850	COG3712	iron ion homeostasis
BG535_RS03890	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BG535_RS03895	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BG535_RS03900	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BG535_RS03905	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BG535_RS03915	COG0142	geranyltranstransferase activity
BG535_RS03925	COG0583	DNA-binding transcription factor activity
BG535_RS03935	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
BG535_RS03940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BG535_RS03955	COG2994	toxin metabolic process
BG535_RS03965	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
BG535_RS03970	COG2274	protein secretion by the type I secretion system
BG535_RS03975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BG535_RS03980	COG1538	Outer membrane efflux protein
BG535_RS03995	COG0765	amino acid transport
BG535_RS04000	COG0765	amino acid transport
BG535_RS04005	COG1126	abc transporter atp-binding protein
BG535_RS04025	COG1028	Short-chain dehydrogenase reductase Sdr
BG535_RS04035	COG1802	Transcriptional regulator
BG535_RS04045	COG1802	Transcriptional regulator
BG535_RS04055	COG0318	PFAM AMP-dependent synthetase and ligase
BG535_RS04065	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BG535_RS04085	COG0028	Belongs to the TPP enzyme family
BG535_RS04105	COG0308	aminopeptidase N
BG535_RS04110	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BG535_RS04125	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BG535_RS04130	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BG535_RS04135	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BG535_RS04140	COG0560	Phosphoserine phosphatase
BG535_RS04145	COG0583	DNA-binding transcription factor activity
BG535_RS04150	COG3181	Tripartite tricarboxylate transporter family receptor
BG535_RS04155	COG0028	Belongs to the TPP enzyme family
BG535_RS04170	COG4774	siderophore transport
BG535_RS04175	COG4774	siderophore transport
BG535_RS04185	COG1007	ATP synthesis coupled electron transport
BG535_RS04200	COG0713	ATP synthesis coupled electron transport
BG535_RS04210	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BG535_RS04215	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BG535_RS04220	COG1034	ATP synthesis coupled electron transport
BG535_RS04230	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BG535_RS04235	COG0649	NAD binding
BG535_RS04240	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BG535_RS04245	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BG535_RS04250	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BG535_RS04255	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BG535_RS04285	COG0671	phosphoesterase, PA-phosphatase related
BG535_RS04295	COG1597	lipid kinase activity
BG535_RS04300	COG0583	DNA-binding transcription factor activity
BG535_RS04305	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BG535_RS04315	COG1733	regulation of RNA biosynthetic process
BG535_RS04320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BG535_RS04325	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BG535_RS04340	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
BG535_RS04360	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BG535_RS04380	COG3608	succinylglutamate desuccinylase aspartoacylase
BG535_RS04385	COG0626	cystathionine gamma-synthase activity
BG535_RS04390	COG0583	DNA-binding transcription factor activity
BG535_RS04425	COG3799	methylaspartate ammonia-lyase activity
BG535_RS04435	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BG535_RS04445	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BG535_RS04450	COG0149	triose-phosphate isomerase activity
BG535_RS04470	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BG535_RS04495	COG1185	polyribonucleotide nucleotidyltransferase activity
BG535_RS04500	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BG535_RS04515	COG1183	phosphatidylcholine synthase activity
BG535_RS04520	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BG535_RS04525	COG0440	acetolactate synthase activity
BG535_RS04530	COG0028	Belongs to the TPP enzyme family
BG535_RS04545	COG5265	(ABC) transporter
BG535_RS04550	COG0500	methyltransferase
BG535_RS04570	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
BG535_RS04590	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BG535_RS04600	COG0511	ligase activity, forming carbon-carbon bonds
BG535_RS04625	COG2188	Transcriptional regulator
BG535_RS04630	COG0439	Biotin carboxylase
BG535_RS04635	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BG535_RS04680	COG5265	(ABC) transporter
BG535_RS04690	COG0667	Aldo Keto reductase
BG535_RS04705	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BG535_RS04745	COG0583	DNA-binding transcription factor activity
BG535_RS04770	COG2814	Major facilitator Superfamily
BG535_RS04780	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BG535_RS04795	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BG535_RS04805	COG0287	Prephenate dehydrogenase
BG535_RS04810	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BG535_RS04815	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BG535_RS04835	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BG535_RS04840	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BG535_RS04845	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BG535_RS04850	COG1596	polysaccharide export
BG535_RS04850	COG1555	photosystem II stabilization
BG535_RS04865	COG2951	lytic endotransglycosylase activity
BG535_RS04870	COG0123	including yeast histone deacetylase and acetoin utilization protein
BG535_RS04885	COG1960	acyl-CoA dehydrogenase activity
BG535_RS04890	COG0450	alkyl hydroperoxide reductase
BG535_RS04910	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BG535_RS04940	COG0335	large ribosomal subunit rRNA binding
BG535_RS04955	COG0667	Aldo Keto reductase
BG535_RS04965	COG2814	Major facilitator Superfamily
BG535_RS04970	COG3161	chorismate lyase activity
BG535_RS04975	COG1187	pseudouridine synthase activity
BG535_RS04985	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BG535_RS05005	COG1999	signal sequence binding
BG535_RS05010	COG0339	signal peptide processing
BG535_RS05015	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BG535_RS05020	COG4566	intracellular signal transduction
BG535_RS05030	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BG535_RS05035	COG0508	dehydrogenase complex catalyzes the overall conversion of
BG535_RS05040	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BG535_RS05045	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BG535_RS05055	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BG535_RS05060	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BG535_RS05065	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BG535_RS05070	COG0126	phosphoglycerate kinase activity
BG535_RS05075	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BG535_RS05080	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BG535_RS05095	COG0625	glutathione transferase activity
BG535_RS05130	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BG535_RS05140	COG0521	Mo-molybdopterin cofactor biosynthetic process
BG535_RS05150	COG0739	heme binding
BG535_RS05160	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BG535_RS05195	COG0745	RESPONSE REGULATOR receiver
BG535_RS05210	COG0840	transmembrane signaling receptor activity
BG535_RS05220	COG2201	protein-glutamate methylesterase activity
BG535_RS05225	COG0745	RESPONSE REGULATOR receiver
BG535_RS05230	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
BG535_RS05255	COG0667	Aldo Keto reductase
BG535_RS05265	COG4535	Mg2 and Co2 transporter CorC
BG535_RS05270	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BG535_RS05275	COG1702	phosphate starvation-inducible protein PhoH
BG535_RS05280	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BG535_RS05295	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BG535_RS05300	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BG535_RS05305	COG1862	Preprotein translocase
BG535_RS05310	COG0343	queuine tRNA-ribosyltransferase activity
BG535_RS05315	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BG535_RS05320	COG2027	D-alanyl-D-alanine carboxypeptidase
BG535_RS05325	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BG535_RS05335	COG3468	outer membrane autotransporter barrel domain protein
BG535_RS05350	COG3468	outer membrane autotransporter barrel domain protein
BG535_RS05355	COG1648	precorrin-2 dehydrogenase activity
BG535_RS05355	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BG535_RS05380	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BG535_RS05385	COG0741	lytic transglycosylase activity
BG535_RS05390	COG0436	Aminotransferase
BG535_RS05400	COG0280	phosphate acetyltransferase
BG535_RS05400	COG0281	malic enzyme
BG535_RS05410	COG2732	(Barnase) inhibitor
BG535_RS05425	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BG535_RS05450	COG0248	Ppx GppA phosphatase
BG535_RS05460	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BG535_RS05470	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BG535_RS05475	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BG535_RS05480	COG1534	Rna-binding protein
BG535_RS05510	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BG535_RS05525	COG1295	ribonuclease BN
BG535_RS05535	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BG535_RS05540	COG0745	RESPONSE REGULATOR receiver
BG535_RS05545	COG2205	protein histidine kinase activity
BG535_RS05580	COG1022	Amp-dependent synthetase and ligase
BG535_RS05595	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BG535_RS05600	COG1028	Short-chain dehydrogenase reductase Sdr
BG535_RS05610	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BG535_RS05625	COG1136	(ABC) transporter
BG535_RS05630	COG0084	hydrolase, TatD family'
BG535_RS05660	COG0658	competence protein
BG535_RS05660	COG2333	competence protein COMEC
BG535_RS05670	COG0613	PHP domain protein
BG535_RS05690	COG3539	Fimbrial protein
BG535_RS05695	COG0281	malic enzyme
BG535_RS05695	COG0280	phosphate acetyltransferase
BG535_RS05705	COG1522	sequence-specific DNA binding
BG535_RS05715	COG0567	Dehydrogenase, E1 component
BG535_RS05720	COG0508	dehydrogenase complex catalyzes the overall conversion of
BG535_RS05725	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BG535_RS05730	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BG535_RS05735	COG1028	Short-chain dehydrogenase reductase Sdr
BG535_RS05740	COG0583	DNA-binding transcription factor activity
BG535_RS05750	COG3181	Tripartite tricarboxylate transporter family receptor
BG535_RS05775	COG0180	Tryptophanyl-tRNA synthetase
BG535_RS05780	COG2183	response to ionizing radiation
BG535_RS05785	COG1199	ATP-dependent helicase activity
BG535_RS05795	COG0564	pseudouridine synthase activity
BG535_RS05805	COG3243	poly(R)-hydroxyalkanoic acid synthase
BG535_RS05810	COG1028	Short-chain dehydrogenase reductase Sdr
BG535_RS05815	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
BG535_RS05830	COG0672	)-iron permease
BG535_RS05870	COG0583	DNA-binding transcription factor activity
BG535_RS05880	COG2814	Major facilitator Superfamily
BG535_RS05895	COG1619	proteins homologs of microcin C7 resistance protein MccF
BG535_RS05910	COG2084	Dehydrogenase
BG535_RS05915	COG3181	Tripartite tricarboxylate transporter family receptor
BG535_RS05940	COG2988	succinylglutamate desuccinylase activity
BG535_RS05965	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BG535_RS05970	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BG535_RS05970	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BG535_RS05975	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BG535_RS05980	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BG535_RS05980	COG0047	phosphoribosylformylglycinamidine synthase activity
BG535_RS05985	COG3210	domain, Protein
BG535_RS05985	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
BG535_RS05985	COG3064	Membrane
BG535_RS06015	COG0235	Class ii aldolase
BG535_RS06020	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BG535_RS06025	COG0720	synthase
BG535_RS06030	COG0602	queuosine metabolic process
BG535_RS06055	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BG535_RS06090	COG3181	Tripartite tricarboxylate transporter family receptor
BG535_RS06115	COG3842	ATPase activity
BG535_RS06125	COG0395	ABC-type sugar transport system, permease component
BG535_RS06155	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BG535_RS06160	COG0420	3'-5' exonuclease activity
BG535_RS06200	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BG535_RS06200	COG0519	Catalyzes the synthesis of GMP from XMP
BG535_RS06215	COG3550	peptidyl-serine autophosphorylation
BG535_RS06225	COG0477	Major facilitator Superfamily
BG535_RS06240	COG1228	amidohydrolase
BG535_RS06250	COG1116	anion transmembrane transporter activity
BG535_RS06255	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BG535_RS06290	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BG535_RS06310	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BG535_RS06340	COG2814	Major facilitator Superfamily
BG535_RS06355	COG1280	lysine exporter protein (LysE YggA)
BG535_RS06375	COG0747	negative chemotaxis
BG535_RS06380	COG0601	transmembrane transport
BG535_RS06385	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BG535_RS06390	COG4172	Belongs to the ABC transporter superfamily
BG535_RS06395	COG1609	Transcriptional regulator
BG535_RS06425	COG0586	Pfam SNARE associated Golgi protein
BG535_RS06440	COG0500	methyltransferase
BG535_RS06455	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BG535_RS06465	COG0756	dUTP diphosphatase activity
BG535_RS06480	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BG535_RS06485	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BG535_RS06490	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BG535_RS06495	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BG535_RS06495	COG0072	phenylalanine-tRNA ligase activity
BG535_RS06500	COG0776	regulation of translation
BG535_RS06570	COG0540	Belongs to the ATCase OTCase family
BG535_RS06575	COG2974	May be involved in recombination
BG535_RS06585	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BG535_RS06590	COG0583	DNA-binding transcription factor activity
BG535_RS06610	COG1028	Short-chain dehydrogenase reductase Sdr
BG535_RS06625	COG3842	ATPase activity
BG535_RS06630	COG1250	3-hydroxyacyl-CoA dehydrogenase
BG535_RS06630	COG1024	Enoyl-CoA hydratase
BG535_RS06650	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BG535_RS06655	COG2137	regulation of response to DNA damage stimulus
BG535_RS06665	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BG535_RS06675	COG0045	succinate-CoA ligase (ADP-forming) activity
BG535_RS06680	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BG535_RS06685	COG0861	Integral membrane protein TerC family
BG535_RS06690	COG0861	Integral membrane protein TerC family
BG535_RS06695	COG0181	hydroxymethylbilane synthase activity
BG535_RS06755	COG4964	Belongs to the GSP D family
BG535_RS06780	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BG535_RS06790	COG0583	DNA-binding transcription factor activity
BG535_RS06800	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BG535_RS06805	COG4311	Sarcosine oxidase, delta subunit
BG535_RS06810	COG0446	pyridine nucleotide-disulphide oxidoreductase
BG535_RS06810	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BG535_RS06845	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BG535_RS06850	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BG535_RS06855	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BG535_RS06860	COG0735	belongs to the Fur family
BG535_RS06865	COG0497	DNA recombination
BG535_RS06870	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BG535_RS06875	COG1420	regulation of RNA biosynthetic process
BG535_RS06880	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BG535_RS06890	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BG535_RS06900	COG0443	Heat shock 70 kDa protein
BG535_RS06910	COG0612	Peptidase, M16
BG535_RS06930	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BG535_RS06975	COG0745	RESPONSE REGULATOR receiver
BG535_RS06985	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
BG535_RS06990	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BG535_RS06995	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BG535_RS07010	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BG535_RS07030	COG1193	negative regulation of DNA recombination
BG535_RS07035	COG0492	ferredoxin-NADP+ reductase activity
BG535_RS07040	COG1674	ftsk spoiiie
BG535_RS07045	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BG535_RS07050	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BG535_RS07055	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BG535_RS07080	COG3706	GGDEF domain
BG535_RS07100	COG2814	Major facilitator Superfamily
BG535_RS07130	COG3486	L-lysine 6-monooxygenase (NADPH) activity
BG535_RS07145	COG1028	Short-chain dehydrogenase reductase Sdr
BG535_RS07155	COG3022	response to hydroperoxide
BG535_RS07165	COG1289	transmembrane transporter activity
BG535_RS07185	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BG535_RS07195	COG2197	response regulator
BG535_RS07200	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BG535_RS07205	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BG535_RS07210	COG0189	ligase activity
BG535_RS07220	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BG535_RS07225	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BG535_RS07235	COG1764	response to oxidative stress
BG535_RS07240	COG2423	ornithine cyclodeaminase activity
BG535_RS07250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BG535_RS07255	COG0765	amino acid transport
BG535_RS07260	COG0765	amino acid transport
BG535_RS07265	COG1126	abc transporter atp-binding protein
BG535_RS07320	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BG535_RS07330	COG2944	sequence-specific DNA binding
BG535_RS07340	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BG535_RS07345	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BG535_RS07350	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BG535_RS07355	COG0009	L-threonylcarbamoyladenylate synthase
BG535_RS07360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BG535_RS07365	COG1414	Transcriptional regulator
BG535_RS07380	COG0765	amino acid transport
BG535_RS07385	COG1126	abc transporter atp-binding protein
BG535_RS07390	COG0028	Belongs to the TPP enzyme family
BG535_RS07405	COG0028	Belongs to the TPP enzyme family
BG535_RS07410	COG0583	DNA-binding transcription factor activity
BG535_RS07415	COG4974	Belongs to the 'phage' integrase family
BG535_RS07420	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BG535_RS07425	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BG535_RS07440	COG1686	Belongs to the peptidase S11 family
BG535_RS07450	COG2814	Major facilitator Superfamily
BG535_RS07460	COG1074	ATP-dependent DNA helicase activity
BG535_RS07470	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BG535_RS07475	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BG535_RS07480	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BG535_RS07500	COG2321	neutral zinc metallopeptidase
BG535_RS07505	COG0009	L-threonylcarbamoyladenylate synthase
BG535_RS07550	COG3360	Dodecin
BG535_RS07555	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BG535_RS07560	COG2850	peptidyl-arginine hydroxylation
BG535_RS07565	COG3539	Fimbrial protein
BG535_RS07570	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BG535_RS07575	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BG535_RS07580	COG1994	Peptidase M50
BG535_RS07590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BG535_RS07595	COG0765	amino acid transport
BG535_RS07600	COG1126	abc transporter atp-binding protein
BG535_RS07605	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BG535_RS07610	COG1758	RNA polymerase activity
BG535_RS07615	COG0194	GDP metabolic process
BG535_RS07620	COG3258	Cytochrome c
BG535_RS07625	COG2863	cytochrome
BG535_RS07630	COG1028	Short-chain dehydrogenase reductase Sdr
BG535_RS07635	COG0791	NLP P60 protein
BG535_RS07640	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BG535_RS07660	COG1561	YicC-like family, N-terminal region
BG535_RS07665	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BG535_RS07680	COG0840	transmembrane signaling receptor activity
BG535_RS07685	COG2200	EAL domain
BG535_RS07685	COG2199	diguanylate cyclase activity
BG535_RS07690	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BG535_RS07700	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BG535_RS07705	COG0174	glutamine synthetase
BG535_RS07715	COG2204	response regulator
BG535_RS07720	COG0583	DNA-binding transcription factor activity
BG535_RS07725	COG1741	Belongs to the pirin family
BG535_RS07730	COG1741	Belongs to the pirin family
BG535_RS07740	COG3842	ATPase activity
BG535_RS07745	COG1178	ABC-type Fe3 transport system permease component
BG535_RS07750	COG1840	ABC-type Fe3 transport system, periplasmic component
BG535_RS07760	COG0583	DNA-binding transcription factor activity
BG535_RS07770	COG0656	L-ascorbic acid biosynthetic process
BG535_RS07785	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BG535_RS07790	COG0583	DNA-binding transcription factor activity
BG535_RS07805	COG0783	Belongs to the Dps family
BG535_RS07825	COG0463	Glycosyl transferase, family 2
BG535_RS07845	COG0438	transferase activity, transferring glycosyl groups
BG535_RS07860	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BG535_RS07885	COG0300	oxidoreductase activity
BG535_RS07930	COG0861	Integral membrane protein TerC family
BG535_RS07935	COG1028	Short-chain dehydrogenase reductase Sdr
BG535_RS07955	COG0714	Associated with various cellular activities
BG535_RS07990	COG3119	arylsulfatase activity
BG535_RS08015	COG2197	response regulator
BG535_RS08025	COG2944	sequence-specific DNA binding
BG535_RS08030	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
BG535_RS08035	COG0625	glutathione transferase activity
BG535_RS08065	COG0179	Fumarylacetoacetate (FAA) hydrolase
BG535_RS08070	COG1028	Short-chain dehydrogenase reductase Sdr
BG535_RS08115	COG0431	NADPH-dependent FMN reductase
BG535_RS08145	COG1028	Short-chain dehydrogenase reductase Sdr
BG535_RS08150	COG0583	DNA-binding transcription factor activity
BG535_RS08165	COG3181	Tripartite tricarboxylate transporter family receptor
BG535_RS08170	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BG535_RS08170	COG2111	Na H antiporter
BG535_RS08175	COG1006	Multisubunit Na H antiporter MnhC subunit
BG535_RS08180	COG0651	ATP synthesis coupled electron transport
BG535_RS08185	COG1863	multisubunit Na H antiporter MnhE subunit
BG535_RS08190	COG2212	antiporter activity
BG535_RS08215	COG0590	tRNA wobble adenosine to inosine editing
BG535_RS08220	COG1619	proteins homologs of microcin C7 resistance protein MccF
BG535_RS08225	COG1024	Enoyl-CoA hydratase
BG535_RS08240	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BG535_RS08245	COG0488	(ABC) transporter
BG535_RS08280	COG1017	nitric oxide dioxygenase activity
BG535_RS08280	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BG535_RS08285	COG1959	2 iron, 2 sulfur cluster binding
BG535_RS08290	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BG535_RS08310	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BG535_RS08315	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BG535_RS08320	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BG535_RS08325	COG0084	hydrolase, TatD family'
BG535_RS08340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BG535_RS08350	COG1126	abc transporter atp-binding protein
BG535_RS08355	COG0010	Belongs to the arginase family
BG535_RS08360	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BG535_RS08365	COG1012	belongs to the aldehyde dehydrogenase family
BG535_RS08375	COG0028	Belongs to the TPP enzyme family
BG535_RS08385	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BG535_RS08385	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BG535_RS08395	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BG535_RS08415	COG3189	MarR family transcriptional regulator
BG535_RS08420	COG2010	Cytochrome c
BG535_RS08445	COG4336	lyase activity
BG535_RS08455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BG535_RS08455	COG2205	protein histidine kinase activity
BG535_RS08460	COG2197	response regulator
BG535_RS08465	COG3064	Membrane
BG535_RS08465	COG3210	domain, Protein
BG535_RS08465	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
BG535_RS08475	COG3121	Chaperone
BG535_RS08480	COG3188	usher protein
BG535_RS08485	COG3539	Fimbrial protein
BG535_RS08490	COG2831	hemolysin activation secretion protein
BG535_RS08505	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BG535_RS08530	COG0583	DNA-binding transcription factor activity
BG535_RS08555	COG0668	transmembrane transport
BG535_RS08575	COG0483	inositol monophosphate 1-phosphatase activity
BG535_RS08580	COG1253	flavin adenine dinucleotide binding
BG535_RS08585	COG1968	undecaprenyl-diphosphatase activity
BG535_RS08590	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BG535_RS08605	COG0215	cysteine-tRNA ligase activity
BG535_RS08615	COG0825	malonyl-CoA metabolic process
BG535_RS08625	COG0037	tRNA processing
BG535_RS08630	COG0527	aspartate kinase activity
BG535_RS08655	COG1250	3-hydroxyacyl-CoA dehydrogenase
BG535_RS08660	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BG535_RS08660	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BG535_RS08675	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BG535_RS08680	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
BG535_RS08685	COG1028	Short-chain dehydrogenase reductase Sdr
BG535_RS08695	COG0583	DNA-binding transcription factor activity
BG535_RS08720	COG3842	ATPase activity
BG535_RS08730	COG0446	pyridine nucleotide-disulphide oxidoreductase
BG535_RS08730	COG1902	pentaerythritol trinitrate reductase activity
BG535_RS08735	COG1414	Transcriptional regulator
BG535_RS08740	COG1832	CoA-binding protein
BG535_RS08750	COG0251	oxidation-reduction process
BG535_RS08775	COG1902	pentaerythritol trinitrate reductase activity
BG535_RS08785	COG1215	transferase activity, transferring glycosyl groups
BG535_RS08790	COG0726	polysaccharide deacetylase
BG535_RS08790	COG1649	PFAM Uncharacterised BCR, COG1649
BG535_RS08810	COG1846	Transcriptional regulator
BG535_RS08820	COG3468	outer membrane autotransporter barrel domain protein
BG535_RS08825	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BG535_RS08835	COG0556	nucleotide-excision repair
BG535_RS08840	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BG535_RS08850	COG1104	cysteine desulfurase activity
BG535_RS08855	COG0822	iron-sulfur transferase activity
BG535_RS08860	COG0316	Belongs to the HesB IscA family
BG535_RS08865	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BG535_RS08870	COG0443	Heat shock 70 kDa protein
BG535_RS08875	COG0633	Ferredoxin
BG535_RS08895	COG1024	Enoyl-CoA hydratase
BG535_RS08910	COG3395	kinase activity
BG535_RS08915	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BG535_RS08930	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BG535_RS08940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BG535_RS08965	COG0747	negative chemotaxis
BG535_RS08970	COG0601	transmembrane transport
BG535_RS08975	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BG535_RS08980	COG4172	Belongs to the ABC transporter superfamily
BG535_RS08985	COG0154	amidase activity
BG535_RS09030	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BG535_RS09035	COG0425	Belongs to the sulfur carrier protein TusA family
BG535_RS09045	COG0228	four-way junction DNA binding
BG535_RS09050	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BG535_RS09055	COG0336	Belongs to the RNA methyltransferase TrmD family
BG535_RS09060	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BG535_RS09085	COG0642	Histidine kinase
BG535_RS09100	COG0525	valine-tRNA ligase activity
BG535_RS09105	COG0105	UTP biosynthetic process
BG535_RS09110	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BG535_RS09120	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BG535_RS09125	COG0124	histidyl-tRNA synthetase
BG535_RS09130	COG2976	Protein conserved in bacteria
BG535_RS09135	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BG535_RS09140	COG1160	GTP binding
BG535_RS09145	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BG535_RS09150	COG1923	regulation of RNA biosynthetic process
BG535_RS09155	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BG535_RS09160	COG0330	HflC and HflK could
BG535_RS09165	COG0330	HflC and HflK could
BG535_RS09170	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BG535_RS09175	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BG535_RS09180	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BG535_RS09185	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BG535_RS09195	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BG535_RS09230	COG0628	permease
BG535_RS09235	COG0842	Transport permease protein
BG535_RS09240	COG1131	(ABC) transporter
BG535_RS09310	COG0156	8-amino-7-oxononanoate synthase activity
BG535_RS09320	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BG535_RS09320	COG4106	trans-aconitate 2-methyltransferase activity
BG535_RS09325	COG1380	Effector of murein hydrolase LrgA
BG535_RS09345	COG3284	Transcriptional regulator
BG535_RS09350	COG1012	belongs to the aldehyde dehydrogenase family
BG535_RS09365	COG2733	membrane
BG535_RS09370	COG0583	DNA-binding transcription factor activity
BG535_RS09375	COG0384	phenazine biosynthesis protein PhzF
BG535_RS09380	COG5507	3-demethylubiquinone-9 3-methyltransferase
BG535_RS09385	COG2169	Transcriptional regulator
BG535_RS09415	COG0659	secondary active sulfate transmembrane transporter activity
BG535_RS09440	COG1132	(ABC) transporter
BG535_RS09490	COG2207	Transcriptional regulator
BG535_RS09630	COG2346	COG2346, Truncated hemoglobins
BG535_RS09675	COG0183	Belongs to the thiolase family
BG535_RS09690	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BG535_RS09695	COG0633	Ferredoxin
BG535_RS09705	COG1024	Enoyl-CoA hydratase
BG535_RS09715	COG4638	Rieske (2fe-2S)
BG535_RS09725	COG0559	Belongs to the binding-protein-dependent transport system permease family
BG535_RS09745	COG2224	Isocitrate lyase
BG535_RS09750	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BG535_RS09750	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BG535_RS09760	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BG535_RS09765	COG0322	excinuclease ABC activity
BG535_RS09770	COG1472	Belongs to the glycosyl hydrolase 3 family
BG535_RS09775	COG0736	holo-[acyl-carrier-protein] synthase activity
BG535_RS09780	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BG535_RS09790	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BG535_RS09795	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BG535_RS09820	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BG535_RS09835	COG2032	superoxide dismutase activity
BG535_RS09850	COG1024	Enoyl-CoA hydratase
BG535_RS09860	COG1802	Transcriptional regulator
BG535_RS09870	COG0183	Belongs to the thiolase family
BG535_RS09875	COG1942	4-Oxalocrotonate Tautomerase
BG535_RS09885	COG4176	ABC-type proline glycine betaine transport system permease component
BG535_RS09905	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BG535_RS09910	COG2814	Major facilitator Superfamily
BG535_RS09915	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BG535_RS09920	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BG535_RS09950	COG2814	Major facilitator Superfamily
BG535_RS09955	COG0495	leucyl-tRNA aminoacylation
BG535_RS09970	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BG535_RS09980	COG0154	amidase activity
BG535_RS09985	COG1250	3-hydroxyacyl-CoA dehydrogenase
BG535_RS10040	COG0427	acetyl-CoA hydrolase
BG535_RS10045	COG0583	DNA-binding transcription factor activity
BG535_RS10065	COG0730	response to heat
BG535_RS10070	COG0697	spore germination
BG535_RS10105	COG2885	chlorophyll binding
BG535_RS10130	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BG535_RS10135	COG3384	dioxygenase
BG535_RS10150	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BG535_RS10155	COG3474	cytochrome
BG535_RS10165	COG1595	DNA-templated transcription, initiation
BG535_RS10180	COG2204	response regulator
BG535_RS10220	COG4964	Belongs to the GSP D family
BG535_RS10270	COG1846	Transcriptional regulator
BG535_RS10275	COG4172	Belongs to the ABC transporter superfamily
BG535_RS10280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BG535_RS10285	COG0601	transmembrane transport
BG535_RS10290	COG0747	negative chemotaxis
BG535_RS10300	COG0598	Magnesium transport protein CorA
BG535_RS10305	COG0210	DNA helicase
BG535_RS10320	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BG535_RS10325	COG1012	belongs to the aldehyde dehydrogenase family
BG535_RS10330	COG0483	inositol monophosphate 1-phosphatase activity
BG535_RS10335	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BG535_RS10345	COG1045	serine acetyltransferase
BG535_RS10350	COG0166	Belongs to the GPI family
BG535_RS10365	COG2197	response regulator
BG535_RS10385	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BG535_RS10400	COG1960	acyl-CoA dehydrogenase activity
BG535_RS10405	COG1028	Short-chain dehydrogenase reductase Sdr
BG535_RS10410	COG0183	Belongs to the thiolase family
BG535_RS10420	COG1024	Enoyl-CoA hydratase
BG535_RS10435	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BG535_RS10440	COG0583	DNA-binding transcription factor activity
BG535_RS10445	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BG535_RS10450	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BG535_RS10455	COG0740	serine-type endopeptidase activity
BG535_RS10460	COG0544	peptidyl-prolyl cis-trans isomerase activity
BG535_RS10480	COG1278	Cold shock
BG535_RS10515	COG2171	N-acyltransferase activity
BG535_RS10520	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BG535_RS10525	COG2890	protein-(glutamine-N5) methyltransferase activity
BG535_RS10530	COG0488	(ABC) transporter
BG535_RS10535	COG4771	TonB-dependent receptor
BG535_RS10540	COG0210	DNA helicase
BG535_RS10560	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BG535_RS10565	COG0196	riboflavin kinase activity
BG535_RS10570	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BG535_RS10575	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BG535_RS10580	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BG535_RS10590	COG1522	sequence-specific DNA binding
BG535_RS10610	COG2951	lytic endotransglycosylase activity
BG535_RS10615	COG2833	Protein of unknown function (DUF455)
BG535_RS10635	COG0189	ligase activity
BG535_RS10635	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BG535_RS10640	COG1181	Belongs to the D-alanine--D-alanine ligase family
BG535_RS10640	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BG535_RS10645	COG3237	CsbD-like
BG535_RS10655	COG2823	Periplasmic or secreted lipoprotein
BG535_RS10670	COG4181	ATPase activity
BG535_RS10680	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BG535_RS10685	COG0584	glycerophosphoryl diester phosphodiesterase
BG535_RS10690	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BG535_RS10700	COG0678	peroxiredoxin activity
BG535_RS10700	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BG535_RS10710	COG0789	Transcriptional regulator
BG535_RS10715	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BG535_RS10745	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BG535_RS10750	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BG535_RS10760	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BG535_RS10765	COG2252	PERMEase
BG535_RS10775	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BG535_RS10805	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BG535_RS10810	COG2358	TRAP transporter, solute receptor (TAXI family
BG535_RS10840	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BG535_RS10845	COG1366	Belongs to the anti-sigma-factor antagonist family
BG535_RS10850	COG2172	sigma factor antagonist activity
BG535_RS10855	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BG535_RS10865	COG2208	phosphoserine phosphatase activity
BG535_RS10865	COG2770	Histidine kinase
BG535_RS10890	COG1595	DNA-templated transcription, initiation
BG535_RS10905	COG4792	protein secretion
BG535_RS10910	COG4791	protein targeting
BG535_RS10915	COG4794	Type iii secretion
BG535_RS10920	COG4790	Type iii secretion
BG535_RS10955	COG4669	(LipO)protein
BG535_RS11020	COG4789	Type iii secretion
BG535_RS11050	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BG535_RS11055	COG0840	transmembrane signaling receptor activity
BG535_RS11060	COG2233	PERMEase
BG535_RS11080	COG0492	ferredoxin-NADP+ reductase activity
BG535_RS11085	COG1840	ABC-type Fe3 transport system, periplasmic component
BG535_RS11090	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BG535_RS11095	COG1178	ABC-type Fe3 transport system permease component
BG535_RS11100	COG3842	ATPase activity
BG535_RS11105	COG0583	DNA-binding transcription factor activity
BG535_RS11125	COG0501	Belongs to the peptidase M48B family
BG535_RS11135	COG0697	spore germination
BG535_RS11145	COG1846	Transcriptional regulator
BG535_RS11155	COG1566	PFAM secretion protein HlyD family protein
BG535_RS11160	COG2814	Major facilitator Superfamily
BG535_RS11165	COG0473	3-isopropylmalate dehydrogenase activity
BG535_RS11175	COG0747	negative chemotaxis
BG535_RS11185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BG535_RS11200	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BG535_RS11225	COG1012	belongs to the aldehyde dehydrogenase family
BG535_RS11235	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BG535_RS11240	COG1115	amino acid carrier protein
BG535_RS11245	COG0433	COG0433 Predicted ATPase
BG535_RS11250	COG0217	transcriptional regulatory protein
BG535_RS11255	COG0151	Belongs to the GarS family
BG535_RS11260	COG0408	coproporphyrinogen oxidase activity
BG535_RS11265	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BG535_RS11270	COG0799	negative regulation of ribosome biogenesis
BG535_RS11275	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BG535_RS11280	COG0424	maF-like protein
BG535_RS11285	COG3468	outer membrane autotransporter barrel domain protein
BG535_RS11325	COG1530	ribonuclease E activity
BG535_RS11330	COG0077	Prephenate dehydratase
BG535_RS11345	COG1132	(ABC) transporter
BG535_RS11350	COG0859	PFAM glycosyl transferase family 9
BG535_RS11375	COG2194	sulfuric ester hydrolase activity
BG535_RS11380	COG0438	transferase activity, transferring glycosyl groups
BG535_RS11385	COG0463	Glycosyl transferase, family 2
BG535_RS11390	COG0726	polysaccharide deacetylase
BG535_RS11395	COG0438	transferase activity, transferring glycosyl groups
BG535_RS11410	COG1643	Atp-dependent helicase
BG535_RS11415	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BG535_RS11415	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BG535_RS11420	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
BG535_RS11430	COG0704	Plays a role in the regulation of phosphate uptake
BG535_RS11435	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BG535_RS11440	COG1960	acyl-CoA dehydrogenase activity
BG535_RS11465	COG1177	transmembrane transport
BG535_RS11470	COG1176	ABC-type spermidine putrescine transport system, permease component I
BG535_RS11475	COG3842	ATPase activity
BG535_RS11480	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BG535_RS11495	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BG535_RS11500	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BG535_RS11510	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BG535_RS11510	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BG535_RS11525	COG0372	Belongs to the citrate synthase family
BG535_RS11530	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BG535_RS11535	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BG535_RS11540	COG1053	succinate dehydrogenase
BG535_RS11545	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BG535_RS11550	COG2009	succinate dehydrogenase
BG535_RS11555	COG2188	Transcriptional regulator
BG535_RS11560	COG0039	L-malate dehydrogenase activity
BG535_RS11590	COG1981	membrane
BG535_RS11615	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BG535_RS11625	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BG535_RS11655	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BG535_RS11660	COG0148	phosphopyruvate hydratase activity
BG535_RS11670	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BG535_RS11675	COG0504	CTP synthase activity
BG535_RS11700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BG535_RS11710	COG0747	negative chemotaxis
BG535_RS11715	COG4172	Belongs to the ABC transporter superfamily
BG535_RS11720	COG1446	asparaginase
BG535_RS11750	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BG535_RS11765	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
BG535_RS11770	COG0697	spore germination
BG535_RS11775	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BG535_RS11785	COG3193	protein, possibly involved in utilization of glycolate and propanediol
BG535_RS11795	COG0791	NLP P60 protein
BG535_RS11810	COG0583	DNA-binding transcription factor activity
BG535_RS11825	COG0583	DNA-binding transcription factor activity
BG535_RS11835	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BG535_RS11850	COG0670	Belongs to the BI1 family
BG535_RS11855	COG3181	Tripartite tricarboxylate transporter family receptor
BG535_RS11870	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BG535_RS11880	COG1381	Involved in DNA repair and RecF pathway recombination
BG535_RS11885	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BG535_RS11890	COG0571	ribonuclease III activity
BG535_RS11895	COG0681	Belongs to the peptidase S26 family
BG535_RS11900	COG0481	GTPase activity
BG535_RS11905	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BG535_RS11930	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BG535_RS11935	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BG535_RS11950	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BG535_RS11955	COG0416	fatty acid biosynthetic process
BG535_RS11960	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BG535_RS11965	COG1399	metal-binding, possibly nucleic acid-binding protein
BG535_RS11970	COG0424	maF-like protein
BG535_RS11980	COG3023	N-Acetylmuramoyl-L-alanine amidase
BG535_RS11985	COG1289	transmembrane transporter activity
BG535_RS11995	COG3022	response to hydroperoxide
BG535_RS12010	COG0135	phosphoribosylanthranilate isomerase activity
BG535_RS12025	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BG535_RS12030	COG0101	tRNA pseudouridine synthase activity
BG535_RS12040	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BG535_RS12045	COG0473	3-isopropylmalate dehydrogenase activity
BG535_RS12050	COG0066	3-isopropylmalate dehydratase activity
BG535_RS12055	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BG535_RS12065	COG1122	ATPase activity
BG535_RS12095	COG0437	4 iron, 4 sulfur cluster binding
BG535_RS12100	COG3383	formate dehydrogenase (NAD+) activity
BG535_RS12100	COG0243	molybdopterin cofactor binding
BG535_RS12130	COG0489	protein tyrosine kinase activity
BG535_RS12135	COG0746	molybdenum cofactor guanylyltransferase activity
BG535_RS12140	COG0303	'Molybdopterin
BG535_RS12145	COG1763	Mo-molybdopterin cofactor biosynthetic process
BG535_RS12155	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BG535_RS12160	COG5001	Diguanylate cyclase
BG535_RS12180	COG3842	ATPase activity
BG535_RS12190	COG0406	alpha-ribazole phosphatase activity
BG535_RS12200	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BG535_RS12205	COG0505	Belongs to the CarA family
BG535_RS12210	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BG535_RS12245	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BG535_RS12250	COG1960	acyl-CoA dehydrogenase activity
BG535_RS12260	COG2867	negative regulation of translational initiation
BG535_RS12270	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BG535_RS12275	COG3706	GGDEF domain
BG535_RS12280	COG0330	HflC and HflK could
BG535_RS12295	COG0519	Catalyzes the synthesis of GMP from XMP
BG535_RS12295	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BG535_RS12305	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BG535_RS12310	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BG535_RS12315	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BG535_RS12320	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BG535_RS12330	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BG535_RS12335	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BG535_RS12340	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
BG535_RS12345	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BG535_RS12350	COG0750	zinc metalloprotease
BG535_RS12355	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BG535_RS12365	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BG535_RS12370	COG0233	cytoplasmic translational termination
BG535_RS12375	COG0528	UMP kinase activity
BG535_RS12380	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BG535_RS12385	COG0052	Belongs to the universal ribosomal protein uS2 family
BG535_RS12390	COG0024	Methionine aminopeptidase
BG535_RS12395	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BG535_RS12425	COG0285	dihydrofolate synthase activity
BG535_RS12460	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BG535_RS12470	COG1677	Flagellar hook-basal body complex protein FliE
BG535_RS12480	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BG535_RS12490	COG1157	protein secretion by the type III secretion system
BG535_RS12515	COG1580	Controls the rotational direction of flagella during chemotaxis
BG535_RS12535	COG1338	Plays a role in the flagellum-specific transport system
BG535_RS12555	COG0840	transmembrane signaling receptor activity
BG535_RS12560	COG0840	transmembrane signaling receptor activity
BG535_RS12565	COG0840	transmembrane signaling receptor activity
BG535_RS12575	COG1256	bacterial-type flagellum assembly
BG535_RS12585	COG1706	bacterial-type flagellum-dependent cell motility
BG535_RS12590	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BG535_RS12605	COG1749	Flagellar hook protein flgE
BG535_RS12615	COG1558	bacterial-type flagellum-dependent cell motility
BG535_RS12620	COG1815	bacterial-type flagellum-dependent cell motility
BG535_RS12660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BG535_RS12665	COG0765	amino acid transport
BG535_RS12670	COG1126	abc transporter atp-binding protein
BG535_RS12685	COG4948	Mandelate Racemase Muconate Lactonizing
BG535_RS12690	COG3181	Tripartite tricarboxylate transporter family receptor
BG535_RS12700	COG0066	3-isopropylmalate dehydratase activity
BG535_RS12715	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BG535_RS12725	COG3181	Tripartite tricarboxylate transporter family receptor
BG535_RS12735	COG1802	Transcriptional regulator
BG535_RS12750	COG0583	DNA-binding transcription factor activity
BG535_RS12770	COG1695	Transcriptional regulator
BG535_RS12780	COG3568	Endonuclease Exonuclease Phosphatase
BG535_RS12785	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BG535_RS12800	COG0392	lysyltransferase activity
BG535_RS12835	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BG535_RS12845	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BG535_RS12865	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BG535_RS12895	COG0667	Aldo Keto reductase
BG535_RS12910	COG2259	Doxx family
BG535_RS12945	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BG535_RS12965	COG0386	Belongs to the glutathione peroxidase family
BG535_RS12970	COG0625	glutathione transferase activity
BG535_RS12985	COG0095	Lipoate-protein ligase
BG535_RS13000	COG0688	phosphatidylethanolamine metabolic process
BG535_RS13010	COG1464	Belongs to the NlpA lipoprotein family
BG535_RS13025	COG2363	Small membrane protein
BG535_RS13050	COG3842	ATPase activity
BG535_RS13055	COG0395	ABC-type sugar transport system, permease component
BG535_RS13060	COG1175	transmembrane transport
BG535_RS13065	COG1653	transport
BG535_RS13075	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BG535_RS13090	COG0559	Belongs to the binding-protein-dependent transport system permease family
BG535_RS13110	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BG535_RS13125	COG0697	spore germination
BG535_RS13140	COG2311	Membrane
BG535_RS13165	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BG535_RS13175	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BG535_RS13180	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BG535_RS13185	COG1760	l-serine dehydratase
BG535_RS13190	COG1283	sodium-dependent phosphate transmembrane transporter activity
BG535_RS13195	COG0412	Dienelactone hydrolase
BG535_RS13210	COG1611	Belongs to the LOG family
BG535_RS13230	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BG535_RS13235	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BG535_RS13240	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BG535_RS13245	COG2251	uridine kinase activity
BG535_RS13245	COG0195	Participates in both transcription termination and antitermination
BG535_RS13250	COG0779	Required for maturation of 30S ribosomal subunits
BG535_RS13255	COG1187	pseudouridine synthase activity
BG535_RS13260	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BG535_RS13270	COG0583	DNA-binding transcription factor activity
BG535_RS13280	COG0523	cobalamin synthesis protein
BG535_RS13300	COG0625	glutathione transferase activity
BG535_RS13305	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BG535_RS13310	COG1047	Peptidyl-prolyl cis-trans
BG535_RS13315	COG2003	Belongs to the UPF0758 family
BG535_RS13320	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BG535_RS13325	COG3483	tryptophan 2,3-dioxygenase activity
BG535_RS13330	COG0254	rRNA binding
BG535_RS13340	COG0534	Mate efflux family protein
BG535_RS13360	COG2304	oxidoreductase activity
BG535_RS13380	COG1028	Short-chain dehydrogenase reductase Sdr
BG535_RS13385	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BG535_RS13390	COG1562	ergosterol biosynthetic process
BG535_RS13395	COG1562	ergosterol biosynthetic process
BG535_RS13400	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
BG535_RS13400	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
BG535_RS13405	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BG535_RS13415	COG0842	Transport permease protein
BG535_RS13420	COG1131	(ABC) transporter
BG535_RS13440	COG1477	protein flavinylation
BG535_RS13455	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BG535_RS13470	COG5564	TIM-barrel signal transduction protein
BG535_RS13475	COG5441	Belongs to the UPF0261 family
BG535_RS13485	COG3468	outer membrane autotransporter barrel domain protein
BG535_RS13490	COG3468	outer membrane autotransporter barrel domain protein
BG535_RS13500	COG0542	response to heat
BG535_RS13505	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BG535_RS13520	COG0494	nUDIX hydrolase
BG535_RS13525	COG3530	Putative quorum-sensing-regulated virulence factor
BG535_RS13535	COG1595	DNA-templated transcription, initiation
BG535_RS13540	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BG535_RS13575	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BG535_RS13580	COG0765	amino acid transport
BG535_RS13585	COG0765	amino acid transport
BG535_RS13615	COG3539	Fimbrial protein
BG535_RS13625	COG2050	protein possibly involved in aromatic compounds catabolism
BG535_RS13630	COG1024	Enoyl-CoA hydratase
BG535_RS13635	COG1012	belongs to the aldehyde dehydrogenase family
BG535_RS13650	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BG535_RS13655	COG2151	metal-sulfur cluster biosynthetic enzyme
BG535_RS13660	COG3396	Phenylacetate-CoA oxygenase
BG535_RS13665	COG3460	Phenylacetate-CoA oxygenase
BG535_RS13670	COG3396	Phenylacetate-CoA oxygenase
BG535_RS13675	COG3327	negative regulation of DNA-templated transcription, initiation
BG535_RS13685	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BG535_RS13690	COG0501	Belongs to the peptidase M48B family
BG535_RS13695	COG1162	GTPase activity
BG535_RS13705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BG535_RS13710	COG0601	transmembrane transport
BG535_RS13715	COG0747	negative chemotaxis
BG535_RS13760	COG0668	transmembrane transport
BG535_RS13765	COG0165	Argininosuccinate lyase
BG535_RS13785	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BG535_RS13790	COG0303	'Molybdopterin
BG535_RS13795	COG0521	Mo-molybdopterin cofactor biosynthetic process
BG535_RS13810	COG0315	cyclic pyranopterin monophosphate synthase activity
BG535_RS13820	COG0412	Dienelactone hydrolase
BG535_RS13830	COG0678	peroxiredoxin activity
BG535_RS13840	COG0697	spore germination
BG535_RS13845	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BG535_RS13870	COG0789	Transcriptional regulator
BG535_RS13890	COG1028	Short-chain dehydrogenase reductase Sdr
BG535_RS13900	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BG535_RS13905	COG1845	cytochrome c oxidase, subunit III
BG535_RS13910	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BG535_RS13920	COG0477	Major facilitator Superfamily
BG535_RS13950	COG3468	outer membrane autotransporter barrel domain protein
BG535_RS13955	COG1309	transcriptional regulator
BG535_RS13960	COG2271	Major facilitator Superfamily
BG535_RS13995	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BG535_RS13995	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BG535_RS13995	COG0506	proline dehydrogenase activity
BG535_RS14005	COG3008	intermembrane lipid transfer
BG535_RS14005	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BG535_RS14010	COG2995	paraquat-inducible protein a
BG535_RS14015	COG0542	response to heat
BG535_RS14020	COG4953	penicillin-binding protein 1C
BG535_RS14030	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BG535_RS14035	COG1278	Cold shock
BG535_RS14045	COG0183	Belongs to the thiolase family
BG535_RS14050	COG0038	chloride channel
BG535_RS14055	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BG535_RS14060	COG1570	exodeoxyribonuclease VII activity
BG535_RS14070	COG0811	peptide transport
BG535_RS14075	COG0848	biopolymer transport protein
BG535_RS14080	COG1663	tetraacyldisaccharide 4'-kinase activity
BG535_RS14085	COG2835	tetraacyldisaccharide 4'-kinase activity
BG535_RS14090	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BG535_RS14095	COG0563	adenylate kinase activity
BG535_RS14105	COG0728	peptidoglycan biosynthetic process
BG535_RS14115	COG0268	Binds directly to 16S ribosomal RNA
BG535_RS14150	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BG535_RS14175	COG0436	Aminotransferase
BG535_RS14180	COG3737	Protein of unknown function (DUF498/DUF598)
BG535_RS14185	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BG535_RS14190	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BG535_RS14195	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BG535_RS14205	COG0305	Participates in initiation and elongation during chromosome replication
BG535_RS14215	COG0359	binds to the 23S rRNA
BG535_RS14220	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BG535_RS14225	COG2965	DNA replication, synthesis of RNA primer
BG535_RS14230	COG0360	Binds together with S18 to 16S ribosomal RNA
BG535_RS14235	COG1469	GTP cyclohydrolase I activity
BG535_RS14240	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BG535_RS14245	COG0142	geranyltranstransferase activity
BG535_RS14250	COG1722	exodeoxyribonuclease VII activity
BG535_RS14260	COG3181	Tripartite tricarboxylate transporter family receptor
BG535_RS14280	COG2239	Acts as a magnesium transporter
BG535_RS14290	COG2855	membrane
BG535_RS14300	COG1473	amidohydrolase
BG535_RS14305	COG0318	PFAM AMP-dependent synthetase and ligase
BG535_RS14330	COG1501	Belongs to the glycosyl hydrolase 31 family
BG535_RS14335	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BG535_RS14340	COG2011	ABC-type metal ion transport system permease component
BG535_RS14360	COG1454	alcohol dehydrogenase
BG535_RS14390	COG2186	Transcriptional regulator
BG535_RS14395	COG3181	Tripartite tricarboxylate transporter family receptor
BG535_RS14415	COG1175	transmembrane transport
BG535_RS14420	COG0395	ABC-type sugar transport system, permease component
BG535_RS14425	COG3842	ATPase activity
BG535_RS14430	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BG535_RS14440	COG1653	transport
BG535_RS14460	COG2818	Glycosylase
BG535_RS14465	COG2982	Protein involved in outer membrane biogenesis
BG535_RS14475	COG1309	transcriptional regulator
BG535_RS14480	COG1028	Short-chain dehydrogenase reductase Sdr
BG535_RS14540	COG0583	DNA-binding transcription factor activity
BG535_RS14545	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BG535_RS14550	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BG535_RS14565	COG1028	Short-chain dehydrogenase reductase Sdr
BG535_RS14570	COG0477	Major facilitator Superfamily
BG535_RS14580	COG0583	DNA-binding transcription factor activity
BG535_RS14585	COG1448	Aminotransferase
BG535_RS14590	COG1418	mRNA catabolic process
BG535_RS14615	COG1063	alcohol dehydrogenase
BG535_RS14635	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BG535_RS14645	COG0318	PFAM AMP-dependent synthetase and ligase
BG535_RS14655	COG1522	sequence-specific DNA binding
BG535_RS14660	COG3181	Tripartite tricarboxylate transporter family receptor
BG535_RS14665	COG0307	riboflavin synthase, alpha
BG535_RS14670	COG0154	amidase activity
BG535_RS14680	COG3181	Tripartite tricarboxylate transporter family receptor
BG535_RS14690	COG2807	transmembrane transport
BG535_RS14695	COG0590	tRNA wobble adenosine to inosine editing
BG535_RS14705	COG0583	DNA-binding transcription factor activity
BG535_RS14720	COG1902	pentaerythritol trinitrate reductase activity
BG535_RS14740	COG0559	Belongs to the binding-protein-dependent transport system permease family
BG535_RS14745	COG0251	oxidation-reduction process
BG535_RS14750	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BG535_RS14760	COG1414	Transcriptional regulator
BG535_RS14765	COG1028	Short-chain dehydrogenase reductase Sdr
BG535_RS14780	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BG535_RS14795	COG1024	Enoyl-CoA hydratase
BG535_RS14800	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BG535_RS14805	COG0154	amidase activity
BG535_RS14845	COG3909	cytochrome
BG535_RS14850	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BG535_RS14855	COG0625	glutathione transferase activity
BG535_RS14860	COG0730	response to heat
BG535_RS14865	COG0482	sulfurtransferase activity
BG535_RS14870	COG0583	DNA-binding transcription factor activity
BG535_RS14890	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BG535_RS14910	COG2819	hydrolase of the alpha beta superfamily
BG535_RS14915	COG0247	lactate metabolic process
BG535_RS14920	COG0277	FAD linked oxidase domain protein
BG535_RS14925	COG0277	FAD linked oxidase domain protein
BG535_RS14930	COG0277	FAD linked oxidase domain protein
BG535_RS14935	COG3210	domain, Protein
BG535_RS14935	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
BG535_RS14935	COG3064	Membrane
BG535_RS14935	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
BG535_RS14935	COG3210	domain, Protein
BG535_RS14935	COG3064	Membrane
BG535_RS14940	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BG535_RS14945	COG0312	modulator of DNA gyrase
BG535_RS14980	COG1666	GTP binding
BG535_RS15025	COG3220	belongs to the UPF0276 family
BG535_RS15045	COG0640	Transcriptional regulator
BG535_RS15050	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BG535_RS15055	COG1845	cytochrome c oxidase, subunit III
BG535_RS15060	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BG535_RS15070	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BG535_RS15105	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BG535_RS15110	COG0583	DNA-binding transcription factor activity
BG535_RS15145	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BG535_RS15145	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BG535_RS15160	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BG535_RS15165	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BG535_RS15175	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BG535_RS15190	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BG535_RS15195	COG0316	Belongs to the HesB IscA family
BG535_RS15205	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BG535_RS15210	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BG535_RS15215	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BG535_RS15220	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BG535_RS15225	COG0312	modulator of DNA gyrase
BG535_RS15230	COG3028	Belongs to the UPF0307 family
BG535_RS15245	COG1116	anion transmembrane transporter activity
BG535_RS15250	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BG535_RS15255	COG1335	isochorismatase
BG535_RS15260	COG0346	lactoylglutathione lyase activity
BG535_RS15265	COG0513	Belongs to the DEAD box helicase family
BG535_RS15270	COG3069	C4-dicarboxylate transmembrane transporter activity
BG535_RS15275	COG1802	Transcriptional regulator
BG535_RS15295	COG1042	CoA-binding domain protein
BG535_RS15295	COG0045	succinate-CoA ligase (ADP-forming) activity
BG535_RS15295	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BG535_RS15300	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BG535_RS15315	COG1522	sequence-specific DNA binding
BG535_RS15350	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BG535_RS15355	COG1696	Membrane protein involved in D-alanine export
BG535_RS15380	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BG535_RS15390	COG2264	protein methyltransferase activity
BG535_RS15395	COG0439	Biotin carboxylase
BG535_RS15400	COG0511	ligase activity, forming carbon-carbon bonds
BG535_RS15405	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BG535_RS15410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BG535_RS15415	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BG535_RS15420	COG3150	esterase
BG535_RS15425	COG0557	exoribonuclease II activity
BG535_RS15435	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BG535_RS15455	COG1522	sequence-specific DNA binding
BG535_RS15460	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BG535_RS15465	COG1028	Short-chain dehydrogenase reductase Sdr
BG535_RS15485	COG0653	protein targeting
BG535_RS15490	COG0739	heme binding
BG535_RS15500	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BG535_RS15505	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BG535_RS15515	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BG535_RS15520	COG1181	Belongs to the D-alanine--D-alanine ligase family
BG535_RS15525	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BG535_RS15530	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BG535_RS15540	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BG535_RS15545	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BG535_RS15550	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BG535_RS15560	COG3116	cell division
BG535_RS15565	COG0275	rRNA processing
BG535_RS15570	COG2001	Belongs to the MraZ family
BG535_RS15580	COG0488	(ABC) transporter
BG535_RS15585	COG0418	dihydroorotase activity
BG535_RS15590	COG1473	amidohydrolase
BG535_RS15640	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BG535_RS15645	COG4654	Cytochrome c, class I
BG535_RS15650	COG0129	dihydroxy-acid dehydratase activity
BG535_RS15655	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BG535_RS15705	COG2084	Dehydrogenase
BG535_RS15710	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BG535_RS15725	COG2096	Adenosyltransferase
BG535_RS15740	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BG535_RS15745	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BG535_RS15755	COG0523	cobalamin synthesis protein
BG535_RS15760	COG0735	belongs to the Fur family
BG535_RS15780	COG0803	Belongs to the bacterial solute-binding protein 9 family
BG535_RS15790	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
BG535_RS15800	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BG535_RS15810	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BG535_RS15815	COG1560	Kdo2-lipid A biosynthetic process
BG535_RS15825	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BG535_RS15840	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BG535_RS15845	COG1950	PFAM Membrane protein of
BG535_RS15860	COG0583	DNA-binding transcription factor activity
BG535_RS15870	COG0477	Major facilitator Superfamily
BG535_RS15885	COG0617	tRNA 3'-terminal CCA addition
BG535_RS15895	COG0513	Belongs to the DEAD box helicase family
BG535_RS15900	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BG535_RS15910	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BG535_RS15915	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BG535_RS15975	COG1280	lysine exporter protein (LysE YggA)
BG535_RS15990	COG0405	Gamma-glutamyltransferase
BG535_RS16000	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BG535_RS16030	COG1309	transcriptional regulator
BG535_RS16045	COG0745	RESPONSE REGULATOR receiver
BG535_RS16095	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BG535_RS16120	COG0582	viral genome integration into host DNA
BG535_RS16125	COG0012	GTP binding
BG535_RS16135	COG0193	aminoacyl-tRNA hydrolase activity
BG535_RS16140	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BG535_RS16145	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BG535_RS16155	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BG535_RS16160	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BG535_RS16170	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BG535_RS16195	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
BG535_RS16205	COG1368	sulfuric ester hydrolase activity
BG535_RS16210	COG0642	Histidine kinase
BG535_RS16215	COG0745	RESPONSE REGULATOR receiver
BG535_RS16220	COG0277	FAD linked oxidase domain protein
BG535_RS16235	COG0166	Belongs to the GPI family
BG535_RS16240	COG0438	transferase activity, transferring glycosyl groups
BG535_RS16245	COG0438	transferase activity, transferring glycosyl groups
BG535_RS16260	COG0438	transferase activity, transferring glycosyl groups
BG535_RS16275	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BG535_RS16280	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BG535_RS16285	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
BG535_RS16295	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BG535_RS16305	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BG535_RS16310	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BG535_RS16320	COG0747	negative chemotaxis
BG535_RS16325	COG0601	transmembrane transport
BG535_RS16330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BG535_RS16350	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BG535_RS16355	COG0830	nickel cation binding
BG535_RS16365	COG0804	urea catabolic process
BG535_RS16370	COG0832	Belongs to the urease beta subunit family
BG535_RS16380	COG0831	urea catabolic process
BG535_RS16385	COG0829	nickel cation binding
BG535_RS16395	COG0633	Ferredoxin
BG535_RS16410	COG2188	Transcriptional regulator
BG535_RS16435	COG2719	SpoVR family
BG535_RS16440	COG2718	Belongs to the UPF0229 family
BG535_RS16455	COG1028	Short-chain dehydrogenase reductase Sdr
BG535_RS16460	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BG535_RS16475	COG1960	acyl-CoA dehydrogenase activity
BG535_RS16520	COG0183	Belongs to the thiolase family
BG535_RS16525	COG2030	dehydratase
BG535_RS16570	COG0328	RNA-DNA hybrid ribonuclease activity
BG535_RS16575	COG2226	methyltransferase
BG535_RS16580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BG535_RS16585	COG1388	LysM domain
BG535_RS16585	COG0741	lytic transglycosylase activity
BG535_RS16605	COG2979	Protein of unknown function (DUF533)
BG535_RS16640	COG1271	oxidase subunit
BG535_RS16645	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BG535_RS16650	COG0850	regulation of cytokinetic process
BG535_RS16655	COG2894	cell division
BG535_RS16660	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BG535_RS16680	COG0488	(ABC) transporter
BG535_RS16695	COG0601	transmembrane transport
BG535_RS16705	COG1215	transferase activity, transferring glycosyl groups
BG535_RS16720	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BG535_RS16730	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BG535_RS16750	COG0318	PFAM AMP-dependent synthetase and ligase
BG535_RS16755	COG2188	Transcriptional regulator
BG535_RS16760	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BG535_RS16765	COG2814	Major facilitator Superfamily
BG535_RS16775	COG0259	pyridoxamine-phosphate oxidase activity
BG535_RS16780	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BG535_RS16795	COG0583	DNA-binding transcription factor activity
BG535_RS16800	COG1960	acyl-CoA dehydrogenase activity
BG535_RS16820	COG0134	indole-3-glycerol-phosphate synthase activity
BG535_RS16825	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BG535_RS16830	COG0512	Glutamine amidotransferase of anthranilate synthase
BG535_RS16840	COG0546	phosphoglycolate phosphatase activity
BG535_RS16845	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BG535_RS16850	COG2967	ApaG domain
BG535_RS16855	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
BG535_RS16860	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BG535_RS16865	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BG535_RS16870	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BG535_RS16880	COG0037	tRNA processing
BG535_RS16890	COG3634	alkyl hydroperoxide reductase activity
BG535_RS16895	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BG535_RS16900	COG1024	Enoyl-CoA hydratase
BG535_RS16925	COG0356	it plays a direct role in the translocation of protons across the membrane
BG535_RS16935	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BG535_RS16940	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BG535_RS16945	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BG535_RS16950	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BG535_RS16955	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BG535_RS16960	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BG535_RS16970	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BG535_RS16975	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BG535_RS16980	COG0210	DNA helicase
BG535_RS16990	COG2195	Cleaves the N-terminal amino acid of tripeptides
BG535_RS17000	COG4172	Belongs to the ABC transporter superfamily
BG535_RS17005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BG535_RS17010	COG0601	transmembrane transport
BG535_RS17030	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BG535_RS17035	COG1024	Enoyl-CoA hydratase
BG535_RS17040	COG1024	Enoyl-CoA hydratase
BG535_RS17065	COG1250	3-hydroxyacyl-CoA dehydrogenase
BG535_RS17095	COG2132	Multicopper oxidase
BG535_RS17105	COG1024	Enoyl-CoA hydratase
BG535_RS17105	COG1250	3-hydroxyacyl-CoA dehydrogenase
BG535_RS17115	COG1414	Transcriptional regulator
BG535_RS17125	COG0154	amidase activity
BG535_RS17155	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BG535_RS17160	COG3568	Endonuclease Exonuclease Phosphatase
BG535_RS17165	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BG535_RS17200	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BG535_RS17210	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BG535_RS17225	COG1137	ATPase activity
BG535_RS17240	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BG535_RS17245	COG2010	Cytochrome c
BG535_RS17245	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BG535_RS17255	COG1660	Displays ATPase and GTPase activities
BG535_RS17260	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BG535_RS17295	COG3181	Tripartite tricarboxylate transporter family receptor
BG535_RS17305	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BG535_RS17310	COG2890	protein-(glutamine-N5) methyltransferase activity
BG535_RS17315	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BG535_RS17320	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BG535_RS17370	COG1960	acyl-CoA dehydrogenase activity
BG535_RS17380	COG0183	Belongs to the thiolase family
BG535_RS17385	COG1522	sequence-specific DNA binding
BG535_RS17390	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BG535_RS17410	COG1024	Enoyl-CoA hydratase
BG535_RS17425	COG0604	alcohol dehydrogenase
BG535_RS17445	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BG535_RS17455	COG1960	acyl-CoA dehydrogenase activity
BG535_RS17460	COG1960	acyl-CoA dehydrogenase activity
BG535_RS17465	COG0277	FAD linked oxidase domain protein
BG535_RS17475	COG3181	Tripartite tricarboxylate transporter family receptor
BG535_RS17500	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BG535_RS17510	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BG535_RS17515	COG3181	Tripartite tricarboxylate transporter family receptor
BG535_RS17520	COG1960	acyl-CoA dehydrogenase activity
BG535_RS17540	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BG535_RS17545	COG1024	Enoyl-CoA hydratase
BG535_RS17550	COG1960	acyl-CoA dehydrogenase activity
BG535_RS17570	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BG535_RS17575	COG0022	dehydrogenase e1 component
BG535_RS17580	COG1024	Enoyl-CoA hydratase
BG535_RS17585	COG0508	dehydrogenase complex catalyzes the overall conversion of
BG535_RS17605	COG0683	leucine binding
BG535_RS17610	COG0559	Belongs to the binding-protein-dependent transport system permease family
BG535_RS17615	COG0411	ABC transporter
BG535_RS17625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BG535_RS17640	COG3181	Tripartite tricarboxylate transporter family receptor
BG535_RS17670	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BG535_RS17675	COG0793	Belongs to the peptidase S41A family
BG535_RS17680	COG4942	peptidase
BG535_RS17685	COG0588	phosphoglycerate mutase activity
BG535_RS17690	COG1054	Belongs to the UPF0176 family
BG535_RS17695	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BG535_RS17700	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BG535_RS17705	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BG535_RS17710	COG3181	Tripartite tricarboxylate transporter family receptor
BG535_RS17725	COG2226	methyltransferase
BG535_RS17730	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
BG535_RS17745	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BG535_RS17750	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BG535_RS17775	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BG535_RS17800	COG1335	isochorismatase
BG535_RS17805	COG2309	aminopeptidase activity
BG535_RS17810	COG0596	Alpha beta hydrolase
BG535_RS17815	COG3473	Maleate cis-trans isomerase
BG535_RS17825	COG2068	MobA-Related Protein
BG535_RS17850	COG2204	response regulator
BG535_RS17855	COG5000	phosphorelay sensor kinase activity
BG535_RS17865	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BG535_RS17865	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BG535_RS17875	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
BG535_RS17905	COG0583	DNA-binding transcription factor activity
BG535_RS17920	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BG535_RS17925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BG535_RS17930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BG535_RS17945	COG0758	DNA mediated transformation
BG535_RS17950	COG1522	sequence-specific DNA binding
BG535_RS17960	COG0242	peptide deformylase activity
BG535_RS17975	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BG535_RS17985	COG0546	phosphoglycolate phosphatase activity
BG535_RS18005	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BG535_RS18010	COG1942	4-Oxalocrotonate Tautomerase
BG535_RS18015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BG535_RS18040	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BG535_RS18060	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BG535_RS18065	COG1024	Enoyl-CoA hydratase
BG535_RS18070	COG1414	Transcriptional regulator
BG535_RS18075	COG0318	PFAM AMP-dependent synthetase and ligase
BG535_RS18080	COG3181	Tripartite tricarboxylate transporter family receptor
BG535_RS18110	COG0583	DNA-binding transcription factor activity
BG535_RS18125	COG3422	double-strand break repair
BG535_RS18130	COG0330	HflC and HflK could
BG535_RS18140	COG0251	oxidation-reduction process
BG535_RS18190	COG3723	Recombinational DNA repair protein, rece pathway
BG535_RS18225	COG0582	viral genome integration into host DNA
BG535_RS18250	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BG535_RS18260	COG0706	membrane insertase activity
BG535_RS18265	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BG535_RS18270	COG0594	ribonuclease P activity
BG535_RS18275	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BG535_RS18280	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BG535_RS18295	COG1414	Transcriptional regulator
BG535_RS18300	COG0154	amidase activity
BG535_RS18315	COG1304	FMN binding
BG535_RS18335	COG1960	acyl-CoA dehydrogenase activity
BG535_RS18355	COG1960	acyl-CoA dehydrogenase activity
BG535_RS18370	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BG535_RS18385	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BG535_RS18390	COG3181	Tripartite tricarboxylate transporter family receptor
BG535_RS18400	COG2358	TRAP transporter, solute receptor (TAXI family
BG535_RS18410	COG1629	transport
BG535_RS18415	COG2922	Belongs to the Smg family
BG535_RS18440	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BG535_RS18445	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BG535_RS18450	COG1028	Short-chain dehydrogenase reductase Sdr
BG535_RS18455	COG1012	belongs to the aldehyde dehydrogenase family
BG535_RS18465	COG0028	Belongs to the TPP enzyme family
BG535_RS18470	COG1522	sequence-specific DNA binding
BG535_RS18475	COG3781	membrane
BG535_RS18485	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BG535_RS18505	COG4206	TonB-dependent receptor
BG535_RS18510	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BG535_RS18515	COG2022	thiamine diphosphate biosynthetic process
BG535_RS18520	COG0351	phosphomethylpyrimidine kinase
BG535_RS18525	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BG535_RS18540	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BG535_RS18550	COG0628	permease
BG535_RS18560	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BG535_RS18575	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BG535_RS18580	COG0049	tRNA binding
BG535_RS18585	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BG535_RS18590	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BG535_RS18595	COG0051	transcription antitermination factor activity, RNA binding
BG535_RS18600	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BG535_RS18605	COG0088	Forms part of the polypeptide exit tunnel
BG535_RS18610	COG0089	rRNA binding
BG535_RS18615	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BG535_RS18620	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BG535_RS18625	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BG535_RS18630	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BG535_RS18635	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BG535_RS18640	COG0255	Belongs to the universal ribosomal protein uL29 family
BG535_RS18645	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BG535_RS18665	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BG535_RS18670	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BG535_RS18675	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BG535_RS18680	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BG535_RS18685	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BG535_RS18690	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BG535_RS18695	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BG535_RS18700	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BG535_RS18705	COG1841	ribosomal large subunit assembly
BG535_RS18710	COG0200	Binds to the 23S rRNA
BG535_RS18715	COG0201	protein transport
BG535_RS18720	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BG535_RS18725	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BG535_RS18730	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BG535_RS18735	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BG535_RS18740	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BG535_RS18745	COG0202	RNA polymerase activity
BG535_RS18750	COG0203	ribosomal protein L17
BG535_RS18755	COG0537	adenosine 5'-monophosphoramidase activity
BG535_RS18760	COG1324	tolerance protein
BG535_RS18765	COG4232	protein-disulfide reductase activity
BG535_RS18780	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BG535_RS18790	COG1333	cytochrome c biogenesis protein
BG535_RS18795	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BG535_RS18810	COG1965	Belongs to the frataxin family
BG535_RS18820	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BG535_RS18825	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BG535_RS18830	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BG535_RS18845	COG2814	Major facilitator Superfamily
BG535_RS18850	COG0629	single-stranded DNA binding
BG535_RS18890	COG0402	S-adenosylhomocysteine deaminase activity
BG535_RS18900	COG0438	transferase activity, transferring glycosyl groups
BG535_RS18920	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BG535_RS18945	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BG535_RS18950	COG2186	Transcriptional regulator
BG535_RS18970	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BG535_RS18975	COG1956	GAF domain-containing protein
BG535_RS18980	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BG535_RS18995	COG1652	LysM domain
BG535_RS19010	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BG535_RS19025	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BG535_RS19055	COG3181	Tripartite tricarboxylate transporter family receptor
BG535_RS19070	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BG535_RS19085	COG1024	Enoyl-CoA hydratase
BG535_RS19100	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BG535_RS19105	COG1309	transcriptional regulator
BG535_RS19110	COG2816	NAD+ diphosphatase activity
BG535_RS19115	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BG535_RS19200	COG2814	Major facilitator Superfamily
BG535_RS19205	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BG535_RS19225	COG1999	signal sequence binding
BG535_RS19230	COG0109	protoheme IX farnesyltransferase activity
BG535_RS19270	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BG535_RS19290	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BG535_RS19295	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BG535_RS19305	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BG535_RS19310	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
BG535_RS19320	COG0070	glutamate synthase
BG535_RS19320	COG0069	glutamate synthase activity
BG535_RS19320	COG0067	glutamate synthase
BG535_RS19330	COG3047	cAMP biosynthetic process
BG535_RS19340	COG1127	ABC transporter
BG535_RS19345	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BG535_RS19350	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BG535_RS19355	COG2853	Lipoprotein
BG535_RS19365	COG1131	(ABC) transporter
BG535_RS19370	COG0842	Transport permease protein
BG535_RS19380	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BG535_RS19385	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BG535_RS19390	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BG535_RS19395	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BG535_RS19400	COG0131	Imidazoleglycerol-phosphate dehydratase
BG535_RS19405	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BG535_RS19410	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BG535_RS19415	COG0107	imidazoleglycerol-phosphate synthase activity
BG535_RS19420	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BG535_RS19425	COG0140	phosphoribosyl-ATP diphosphatase activity
BG535_RS19430	COG0537	adenosine 5'-monophosphoramidase activity
BG535_RS19435	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BG535_RS19440	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BG535_RS19455	COG3181	Tripartite tricarboxylate transporter family receptor
BG535_RS19490	COG3702	type iv secretory pathway
BG535_RS19495	COG3451	type IV secretory pathway VirB4
BG535_RS19510	COG3736	Type IV secretory pathway, component VirB8
BG535_RS19515	COG3504	Conjugal transfer protein
BG535_RS19520	COG2948	multi-organism process
BG535_RS19525	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
BG535_RS19535	COG0697	spore germination
BG535_RS19555	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BG535_RS19560	COG0747	negative chemotaxis
BG535_RS19565	COG0601	transmembrane transport
BG535_RS19570	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BG535_RS19575	COG0444	Belongs to the ABC transporter superfamily
BG535_RS19585	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BG535_RS19595	COG0494	nUDIX hydrolase
BG535_RS19635	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
BG535_RS19640	COG0237	dephospho-CoA kinase activity
BG535_RS19645	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BG535_RS19660	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BG535_RS19665	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BG535_RS19675	COG0477	Major facilitator Superfamily
BG535_RS19680	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BG535_RS19695	COG1126	abc transporter atp-binding protein
BG535_RS19700	COG0765	amino acid transport
BG535_RS19705	COG4597	amino acid ABC transporter
BG535_RS19710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BG535_RS19715	COG2884	Cell division ATP-binding protein ftsE
BG535_RS19720	COG2177	Part of the ABC transporter FtsEX involved in
BG535_RS19725	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BG535_RS19735	COG1194	a g-specific adenine glycosylase
BG535_RS19745	COG2226	methyltransferase
BG535_RS19755	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BG535_RS19760	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BG535_RS19775	COG1024	Enoyl-CoA hydratase
BG535_RS19795	COG1024	Enoyl-CoA hydratase
BG535_RS19800	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BG535_RS19805	COG3181	Tripartite tricarboxylate transporter family receptor
BG535_RS19815	COG0753	catalase activity
BG535_RS19820	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BG535_RS19825	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BG535_RS19835	COG2175	clavaminate synthase activity
BG535_RS19840	COG1473	amidohydrolase
BG535_RS19845	COG4608	Belongs to the ABC transporter superfamily
BG535_RS19850	COG0444	Belongs to the ABC transporter superfamily
BG535_RS19865	COG0747	negative chemotaxis
BG535_RS19870	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BG535_RS19905	COG0436	Aminotransferase
BG535_RS19910	COG1278	Cold shock