locus-tag	class	description
ASC25_RS00005	COG0445	tRNA wobble uridine modification
ASC25_RS00010	COG0357	Ribosomal RNA small subunit methyltransferase G
ASC25_RS00015	COG1192	Involved in chromosome partitioning
ASC25_RS00025	COG1475	DNA binding
ASC25_RS00030	COG0252	asparaginase activity
ASC25_RS00055	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ASC25_RS00065	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ASC25_RS00075	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ASC25_RS00080	COG0081	regulation of translation
ASC25_RS00085	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ASC25_RS00090	COG0222	ribosome binding
ASC25_RS00095	COG0085	RNA polymerase activity
ASC25_RS00100	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ASC25_RS00140	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ASC25_RS00165	COG1024	Enoyl-CoA hydratase
ASC25_RS00185	COG0752	glycyl-tRNA synthetase alpha subunit
ASC25_RS00190	COG0751	glycine-tRNA ligase activity
ASC25_RS00195	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ASC25_RS00200	COG0204	Acyl-transferase
ASC25_RS00215	COG0242	peptide deformylase activity
ASC25_RS00250	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ASC25_RS00255	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ASC25_RS00260	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ASC25_RS00260	COG2813	Specifically methylates the guanine in position
ASC25_RS00275	COG2223	nitrite transmembrane transporter activity
ASC25_RS00285	COG1794	racemase activity, acting on amino acids and derivatives
ASC25_RS00290	COG1126	abc transporter atp-binding protein
ASC25_RS00295	COG0765	amino acid transport
ASC25_RS00300	COG0765	amino acid transport
ASC25_RS00305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASC25_RS00370	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ASC25_RS00400	COG0326	Molecular chaperone. Has ATPase activity
ASC25_RS00405	COG0625	glutathione transferase activity
ASC25_RS00420	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ASC25_RS00425	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ASC25_RS00455	COG0438	transferase activity, transferring glycosyl groups
ASC25_RS00460	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ASC25_RS00465	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ASC25_RS00495	COG0859	PFAM glycosyl transferase family 9
ASC25_RS00510	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ASC25_RS00520	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ASC25_RS00525	COG1127	ABC transporter
ASC25_RS00545	COG1686	Belongs to the peptidase S11 family
ASC25_RS00555	COG2921	Belongs to the UPF0250 family
ASC25_RS00560	COG0321	lipoyl(octanoyl) transferase activity
ASC25_RS00565	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ASC25_RS00600	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ASC25_RS00610	COG0018	arginyl-trna synthetase
ASC25_RS00630	COG0395	ABC-type sugar transport system, permease component
ASC25_RS00635	COG1175	transmembrane transport
ASC25_RS00640	COG1653	transport
ASC25_RS00645	COG3842	ATPase activity
ASC25_RS00650	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ASC25_RS00660	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ASC25_RS00680	COG1609	Transcriptional regulator
ASC25_RS00690	COG0154	amidase activity
ASC25_RS00695	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ASC25_RS00705	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ASC25_RS00715	COG0583	DNA-binding transcription factor activity
ASC25_RS00730	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ASC25_RS00735	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ASC25_RS00750	COG1802	Transcriptional regulator
ASC25_RS00765	COG1024	Enoyl-CoA hydratase
ASC25_RS00775	COG3181	Tripartite tricarboxylate transporter family receptor
ASC25_RS00790	COG1984	allophanate hydrolase subunit 2
ASC25_RS00795	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ASC25_RS00805	COG0583	DNA-binding transcription factor activity
ASC25_RS00810	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ASC25_RS00820	COG5002	protein histidine kinase activity
ASC25_RS00830	COG5002	protein histidine kinase activity
ASC25_RS00835	COG0745	RESPONSE REGULATOR receiver
ASC25_RS00840	COG2226	methyltransferase
ASC25_RS00855	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ASC25_RS00875	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
ASC25_RS00885	COG0513	Belongs to the DEAD box helicase family
ASC25_RS00890	COG1280	lysine exporter protein (LysE YggA)
ASC25_RS00895	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ASC25_RS00930	COG1054	Belongs to the UPF0176 family
ASC25_RS00935	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ASC25_RS00935	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ASC25_RS00945	COG0489	protein tyrosine kinase activity
ASC25_RS00960	COG0717	Belongs to the dCTP deaminase family
ASC25_RS00990	COG2081	HI0933 family
ASC25_RS01000	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ASC25_RS01010	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ASC25_RS01015	COG0509	glycine decarboxylation via glycine cleavage system
ASC25_RS01020	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ASC25_RS01020	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ASC25_RS01060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ASC25_RS01075	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ASC25_RS01085	COG1414	Transcriptional regulator
ASC25_RS01090	COG1028	Short-chain dehydrogenase reductase Sdr
ASC25_RS01095	COG2031	fatty acid transporter
ASC25_RS01100	COG1250	3-hydroxyacyl-CoA dehydrogenase
ASC25_RS01110	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ASC25_RS01115	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ASC25_RS01125	COG4257	antibiotic catabolic process
ASC25_RS01150	COG1012	belongs to the aldehyde dehydrogenase family
ASC25_RS01155	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ASC25_RS01160	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ASC25_RS01185	COG1028	Short-chain dehydrogenase reductase Sdr
ASC25_RS01195	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ASC25_RS01210	COG2188	Transcriptional regulator
ASC25_RS01215	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ASC25_RS01240	COG0617	tRNA 3'-terminal CCA addition
ASC25_RS01255	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ASC25_RS01260	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ASC25_RS01265	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ASC25_RS01270	COG0586	Pfam SNARE associated Golgi protein
ASC25_RS01275	COG0860	N-Acetylmuramoyl-L-alanine amidase
ASC25_RS01280	COG0802	atpase or kinase
ASC25_RS01285	COG0114	fumarate hydratase activity
ASC25_RS01295	COG3181	Tripartite tricarboxylate transporter family receptor
ASC25_RS01305	COG0405	Gamma-glutamyltransferase
ASC25_RS01310	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ASC25_RS01320	COG1960	acyl-CoA dehydrogenase activity
ASC25_RS01345	COG1294	oxidase, subunit
ASC25_RS01355	COG4988	ABC transporter
ASC25_RS01360	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ASC25_RS01365	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ASC25_RS01380	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ASC25_RS01410	COG2969	positive regulation of protein catabolic process
ASC25_RS01415	COG0625	glutathione transferase activity
ASC25_RS01420	COG2857	Cytochrome c1
ASC25_RS01425	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ASC25_RS01430	COG0723	plastoquinol--plastocyanin reductase activity
ASC25_RS01435	COG1970	mechanosensitive ion channel activity
ASC25_RS01440	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ASC25_RS01455	COG2808	Putative FMN-binding domain
ASC25_RS01460	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ASC25_RS01465	COG0747	negative chemotaxis
ASC25_RS01470	COG0657	acetylesterase activity
ASC25_RS01480	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ASC25_RS01485	COG2207	Transcriptional regulator
ASC25_RS01490	COG0129	dihydroxy-acid dehydratase activity
ASC25_RS01495	COG2814	Major facilitator Superfamily
ASC25_RS01500	COG0583	DNA-binding transcription factor activity
ASC25_RS01510	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
ASC25_RS01580	COG1024	Enoyl-CoA hydratase
ASC25_RS01585	COG1960	acyl-CoA dehydrogenase activity
ASC25_RS01610	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ASC25_RS01615	COG0352	thiamine-phosphate diphosphorylase activity
ASC25_RS01630	COG1678	Uncharacterized ACR, COG1678
ASC25_RS01635	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ASC25_RS01640	COG0540	Belongs to the ATCase OTCase family
ASC25_RS01655	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ASC25_RS01665	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ASC25_RS01700	COG1234	tRNA 3'-trailer cleavage
ASC25_RS01720	COG3064	Membrane
ASC25_RS01750	COG1683	Conserved Protein
ASC25_RS01755	COG1120	ATPase activity
ASC25_RS01760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ASC25_RS01765	COG4558	Periplasmic binding protein
ASC25_RS01770	COG3720	iron ion transport
ASC25_RS01780	COG3712	iron ion homeostasis
ASC25_RS01785	COG1595	DNA-templated transcription, initiation
ASC25_RS01820	COG1802	Transcriptional regulator
ASC25_RS01830	COG3069	C4-dicarboxylate transmembrane transporter activity
ASC25_RS01840	COG1012	belongs to the aldehyde dehydrogenase family
ASC25_RS01875	COG2860	membrane
ASC25_RS01880	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ASC25_RS01885	COG0708	Exodeoxyribonuclease III
ASC25_RS01890	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ASC25_RS01895	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ASC25_RS01900	COG0154	amidase activity
ASC25_RS01905	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ASC25_RS01910	COG1077	Cell shape determining protein MreB Mrl
ASC25_RS01915	COG1792	Involved in formation and maintenance of cell shape
ASC25_RS01925	COG0768	penicillin binding
ASC25_RS01930	COG0772	Belongs to the SEDS family
ASC25_RS01935	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ASC25_RS01940	COG0471	metal ion transport
ASC25_RS01945	COG1309	transcriptional regulator
ASC25_RS01955	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ASC25_RS01970	COG2823	Periplasmic or secreted lipoprotein
ASC25_RS01975	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ASC25_RS01990	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ASC25_RS02010	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ASC25_RS02020	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ASC25_RS02040	COG0492	ferredoxin-NADP+ reductase activity
ASC25_RS02050	COG3181	Tripartite tricarboxylate transporter family receptor
ASC25_RS02055	COG1024	Enoyl-CoA hydratase
ASC25_RS02055	COG1250	3-hydroxyacyl-CoA dehydrogenase
ASC25_RS02060	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ASC25_RS02065	COG0028	Belongs to the TPP enzyme family
ASC25_RS02090	COG3181	Tripartite tricarboxylate transporter family receptor
ASC25_RS02100	COG0697	spore germination
ASC25_RS02130	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ASC25_RS02135	COG0463	Glycosyl transferase, family 2
ASC25_RS02155	COG0786	glutamate:sodium symporter activity
ASC25_RS02165	COG2031	fatty acid transporter
ASC25_RS02180	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ASC25_RS02185	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ASC25_RS02195	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ASC25_RS02210	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ASC25_RS02220	COG1285	pathogenesis
ASC25_RS02225	COG1253	flavin adenine dinucleotide binding
ASC25_RS02230	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ASC25_RS02235	COG1024	Enoyl-CoA hydratase
ASC25_RS02240	COG3181	Tripartite tricarboxylate transporter family receptor
ASC25_RS02245	COG0583	DNA-binding transcription factor activity
ASC25_RS02250	COG1960	acyl-CoA dehydrogenase activity
ASC25_RS02260	COG0183	Belongs to the thiolase family
ASC25_RS02280	COG0583	DNA-binding transcription factor activity
ASC25_RS02285	COG1278	Cold shock
ASC25_RS02295	COG1802	Transcriptional regulator
ASC25_RS02300	COG1012	belongs to the aldehyde dehydrogenase family
ASC25_RS02305	COG2031	fatty acid transporter
ASC25_RS02310	COG1017	nitric oxide dioxygenase activity
ASC25_RS02310	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ASC25_RS02315	COG0251	oxidation-reduction process
ASC25_RS02335	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ASC25_RS02345	COG0583	DNA-binding transcription factor activity
ASC25_RS02350	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ASC25_RS02360	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
ASC25_RS02365	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ASC25_RS02370	COG0546	phosphoglycolate phosphatase activity
ASC25_RS02380	COG1530	ribonuclease E activity
ASC25_RS02395	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
ASC25_RS02400	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ASC25_RS02405	COG0159	tryptophan synthase activity
ASC25_RS02410	COG0133	tryptophan synthase activity
ASC25_RS02420	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ASC25_RS02425	COG3228	Belongs to the MtfA family
ASC25_RS02435	COG0251	oxidation-reduction process
ASC25_RS02440	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ASC25_RS02445	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ASC25_RS02460	COG2878	Part of a membrane complex involved in electron transport
ASC25_RS02465	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ASC25_RS02500	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ASC25_RS02520	COG1268	BioY protein
ASC25_RS02525	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ASC25_RS02530	COG1122	ATPase activity
ASC25_RS02535	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ASC25_RS02550	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ASC25_RS02555	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ASC25_RS02565	COG1196	nuclear chromosome segregation
ASC25_RS02570	COG0477	Major facilitator Superfamily
ASC25_RS02575	COG1573	uracil-dna glycosylase
ASC25_RS02580	COG1214	PFAM Peptidase M22, glycoprotease
ASC25_RS02605	COG0450	alkyl hydroperoxide reductase
ASC25_RS02610	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ASC25_RS02620	COG2223	nitrite transmembrane transporter activity
ASC25_RS02630	COG2186	Transcriptional regulator
ASC25_RS02650	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ASC25_RS02660	COG0583	DNA-binding transcription factor activity
ASC25_RS02670	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ASC25_RS02675	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ASC25_RS02680	COG0137	argininosuccinate synthase activity
ASC25_RS02685	COG3158	transport of potassium into the cell
ASC25_RS02690	COG0642	Histidine kinase
ASC25_RS02720	COG0776	regulation of translation
ASC25_RS02725	COG3128	pkhd-type hydroxylase
ASC25_RS02735	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ASC25_RS02740	COG0557	exoribonuclease II activity
ASC25_RS02765	COG0679	Auxin Efflux Carrier
ASC25_RS02770	COG2391	methyltransferase activity
ASC25_RS02775	COG0069	glutamate synthase activity
ASC25_RS02785	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ASC25_RS02795	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
ASC25_RS02800	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ASC25_RS02835	COG3706	GGDEF domain
ASC25_RS02850	COG1053	succinate dehydrogenase
ASC25_RS02855	COG0583	DNA-binding transcription factor activity
ASC25_RS02865	COG1053	succinate dehydrogenase
ASC25_RS02885	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ASC25_RS02890	COG0459	protein refolding
ASC25_RS02895	COG3468	outer membrane autotransporter barrel domain protein
ASC25_RS02910	COG1252	NADH dehydrogenase
ASC25_RS02915	COG0284	orotidine-5'-phosphate decarboxylase activity
ASC25_RS02920	COG1546	Belongs to the CinA family
ASC25_RS02920	COG1058	Belongs to the CinA family
ASC25_RS02925	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ASC25_RS02935	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ASC25_RS02940	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ASC25_RS02975	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
ASC25_RS02980	COG3639	organic phosphonate transmembrane transporter activity
ASC25_RS02985	COG3639	organic phosphonate transmembrane transporter activity
ASC25_RS03005	COG0742	ribosomal rna small subunit methyltransferase
ASC25_RS03010	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ASC25_RS03015	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ASC25_RS03020	COG3135	benzoate transporter
ASC25_RS03035	COG0640	Transcriptional regulator
ASC25_RS03065	COG4172	Belongs to the ABC transporter superfamily
ASC25_RS03070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASC25_RS03075	COG0601	transmembrane transport
ASC25_RS03085	COG0281	malic enzyme
ASC25_RS03085	COG0280	phosphate acetyltransferase
ASC25_RS03145	COG0583	DNA-binding transcription factor activity
ASC25_RS03155	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ASC25_RS03160	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
ASC25_RS03165	COG0167	dihydroorotate dehydrogenase activity
ASC25_RS03185	COG1414	Transcriptional regulator
ASC25_RS03190	COG1058	Belongs to the CinA family
ASC25_RS03190	COG1546	Belongs to the CinA family
ASC25_RS03210	COG0513	Belongs to the DEAD box helicase family
ASC25_RS03240	COG0429	hydrolase of the alpha beta-hydrolase fold
ASC25_RS03245	COG4783	chaperone-mediated protein folding
ASC25_RS03260	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ASC25_RS03285	COG0006	proline dipeptidase activity
ASC25_RS03295	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ASC25_RS03315	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ASC25_RS03320	COG0632	four-way junction helicase activity
ASC25_RS03335	COG2255	four-way junction helicase activity
ASC25_RS03340	COG0514	ATP-dependent DNA helicase (RecQ)
ASC25_RS03355	COG0288	reversible hydration of carbon dioxide
ASC25_RS03360	COG0154	amidase activity
ASC25_RS03370	COG4211	Belongs to the binding-protein-dependent transport system permease family
ASC25_RS03400	COG1464	Belongs to the NlpA lipoprotein family
ASC25_RS03545	COG1196	nuclear chromosome segregation
ASC25_RS03615	COG2135	peptidase activity
ASC25_RS03630	COG0494	nUDIX hydrolase
ASC25_RS03635	COG0442	prolyl-tRNA aminoacylation
ASC25_RS03640	COG0824	Thioesterase
ASC25_RS03645	COG0811	peptide transport
ASC25_RS03650	COG0848	biopolymer transport protein
ASC25_RS03660	COG0823	Involved in the tonB-independent uptake of proteins
ASC25_RS03675	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ASC25_RS03680	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
ASC25_RS03715	COG0700	Nucleoside recognition
ASC25_RS03720	COG0469	pyruvate kinase activity
ASC25_RS03725	COG1929	Belongs to the glycerate kinase type-1 family
ASC25_RS03730	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ASC25_RS03735	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ASC25_RS03740	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ASC25_RS03750	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ASC25_RS03760	COG2154	pterin-4-alpha-carbinolamine dehydratase
ASC25_RS03785	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ASC25_RS03790	COG0154	amidase activity
ASC25_RS03800	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASC25_RS03805	COG0601	transmembrane transport
ASC25_RS03810	COG0747	negative chemotaxis
ASC25_RS03830	COG0019	diaminopimelate decarboxylase activity
ASC25_RS03845	COG2353	YceI-like domain
ASC25_RS03850	COG4774	siderophore transport
ASC25_RS03855	COG3712	iron ion homeostasis
ASC25_RS03895	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ASC25_RS03900	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ASC25_RS03905	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ASC25_RS03910	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ASC25_RS03920	COG0142	geranyltranstransferase activity
ASC25_RS03930	COG0583	DNA-binding transcription factor activity
ASC25_RS03940	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
ASC25_RS03945	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ASC25_RS03960	COG2994	toxin metabolic process
ASC25_RS03970	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
ASC25_RS03975	COG2274	protein secretion by the type I secretion system
ASC25_RS03980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASC25_RS03985	COG1538	Outer membrane efflux protein
ASC25_RS04000	COG0765	amino acid transport
ASC25_RS04005	COG0765	amino acid transport
ASC25_RS04010	COG1126	abc transporter atp-binding protein
ASC25_RS04030	COG1028	Short-chain dehydrogenase reductase Sdr
ASC25_RS04040	COG1802	Transcriptional regulator
ASC25_RS04050	COG1802	Transcriptional regulator
ASC25_RS04060	COG0318	PFAM AMP-dependent synthetase and ligase
ASC25_RS04070	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ASC25_RS04090	COG0028	Belongs to the TPP enzyme family
ASC25_RS04110	COG0308	aminopeptidase N
ASC25_RS04115	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ASC25_RS04125	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ASC25_RS04130	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ASC25_RS04135	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ASC25_RS04140	COG0560	Phosphoserine phosphatase
ASC25_RS04145	COG0583	DNA-binding transcription factor activity
ASC25_RS04150	COG3181	Tripartite tricarboxylate transporter family receptor
ASC25_RS04155	COG0028	Belongs to the TPP enzyme family
ASC25_RS04170	COG4774	siderophore transport
ASC25_RS04175	COG4774	siderophore transport
ASC25_RS04185	COG1007	ATP synthesis coupled electron transport
ASC25_RS04200	COG0713	ATP synthesis coupled electron transport
ASC25_RS04210	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ASC25_RS04215	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ASC25_RS04220	COG1034	ATP synthesis coupled electron transport
ASC25_RS04230	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
ASC25_RS04235	COG0649	NAD binding
ASC25_RS04240	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ASC25_RS04245	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ASC25_RS04250	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ASC25_RS04255	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ASC25_RS04285	COG0671	phosphoesterase, PA-phosphatase related
ASC25_RS04295	COG1597	lipid kinase activity
ASC25_RS04300	COG0583	DNA-binding transcription factor activity
ASC25_RS04305	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ASC25_RS04315	COG1733	regulation of RNA biosynthetic process
ASC25_RS04320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASC25_RS04325	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ASC25_RS04340	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
ASC25_RS04360	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ASC25_RS04380	COG3608	succinylglutamate desuccinylase aspartoacylase
ASC25_RS04385	COG0626	cystathionine gamma-synthase activity
ASC25_RS04390	COG0583	DNA-binding transcription factor activity
ASC25_RS04425	COG3799	methylaspartate ammonia-lyase activity
ASC25_RS04435	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ASC25_RS04445	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ASC25_RS04450	COG0149	triose-phosphate isomerase activity
ASC25_RS04470	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ASC25_RS04485	COG1185	polyribonucleotide nucleotidyltransferase activity
ASC25_RS04490	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ASC25_RS04505	COG1183	phosphatidylcholine synthase activity
ASC25_RS04510	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ASC25_RS04515	COG0440	acetolactate synthase activity
ASC25_RS04520	COG0028	Belongs to the TPP enzyme family
ASC25_RS04535	COG5265	(ABC) transporter
ASC25_RS04540	COG0500	methyltransferase
ASC25_RS04560	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
ASC25_RS04580	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ASC25_RS04590	COG0511	ligase activity, forming carbon-carbon bonds
ASC25_RS04615	COG2188	Transcriptional regulator
ASC25_RS04620	COG0439	Biotin carboxylase
ASC25_RS04625	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ASC25_RS04670	COG5265	(ABC) transporter
ASC25_RS04680	COG0667	Aldo Keto reductase
ASC25_RS04695	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ASC25_RS04735	COG0583	DNA-binding transcription factor activity
ASC25_RS04760	COG2814	Major facilitator Superfamily
ASC25_RS04770	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ASC25_RS04785	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ASC25_RS04795	COG0287	Prephenate dehydrogenase
ASC25_RS04800	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ASC25_RS04805	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ASC25_RS04825	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ASC25_RS04830	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ASC25_RS04835	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ASC25_RS04840	COG1555	photosystem II stabilization
ASC25_RS04840	COG1596	polysaccharide export
ASC25_RS04855	COG2951	lytic endotransglycosylase activity
ASC25_RS04860	COG0123	including yeast histone deacetylase and acetoin utilization protein
ASC25_RS04875	COG1960	acyl-CoA dehydrogenase activity
ASC25_RS04880	COG0450	alkyl hydroperoxide reductase
ASC25_RS04895	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ASC25_RS04900	COG4208	sulfate ABC transporter
ASC25_RS04905	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ASC25_RS04935	COG0335	large ribosomal subunit rRNA binding
ASC25_RS04950	COG0667	Aldo Keto reductase
ASC25_RS04960	COG2814	Major facilitator Superfamily
ASC25_RS04965	COG3161	chorismate lyase activity
ASC25_RS04970	COG1187	pseudouridine synthase activity
ASC25_RS04980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASC25_RS05000	COG1999	signal sequence binding
ASC25_RS05005	COG0339	signal peptide processing
ASC25_RS05010	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ASC25_RS05015	COG4566	intracellular signal transduction
ASC25_RS05025	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ASC25_RS05030	COG0508	dehydrogenase complex catalyzes the overall conversion of
ASC25_RS05035	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ASC25_RS05040	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ASC25_RS05050	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ASC25_RS05055	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ASC25_RS05060	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ASC25_RS05065	COG0126	phosphoglycerate kinase activity
ASC25_RS05070	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ASC25_RS05075	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ASC25_RS05090	COG0625	glutathione transferase activity
ASC25_RS05125	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ASC25_RS05135	COG0521	Mo-molybdopterin cofactor biosynthetic process
ASC25_RS05145	COG0739	heme binding
ASC25_RS05155	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ASC25_RS05190	COG0745	RESPONSE REGULATOR receiver
ASC25_RS05205	COG0840	transmembrane signaling receptor activity
ASC25_RS05215	COG2201	protein-glutamate methylesterase activity
ASC25_RS05220	COG0745	RESPONSE REGULATOR receiver
ASC25_RS05225	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
ASC25_RS05250	COG0667	Aldo Keto reductase
ASC25_RS05260	COG4535	Mg2 and Co2 transporter CorC
ASC25_RS05265	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ASC25_RS05270	COG1702	phosphate starvation-inducible protein PhoH
ASC25_RS05275	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ASC25_RS05290	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ASC25_RS05295	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ASC25_RS05300	COG1862	Preprotein translocase
ASC25_RS05305	COG0343	queuine tRNA-ribosyltransferase activity
ASC25_RS05310	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ASC25_RS05315	COG2027	D-alanyl-D-alanine carboxypeptidase
ASC25_RS05320	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ASC25_RS05330	COG3468	outer membrane autotransporter barrel domain protein
ASC25_RS05345	COG3468	outer membrane autotransporter barrel domain protein
ASC25_RS05350	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ASC25_RS05350	COG1648	precorrin-2 dehydrogenase activity
ASC25_RS05375	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ASC25_RS05380	COG0741	lytic transglycosylase activity
ASC25_RS05385	COG0436	Aminotransferase
ASC25_RS05395	COG0281	malic enzyme
ASC25_RS05395	COG0280	phosphate acetyltransferase
ASC25_RS05405	COG2732	(Barnase) inhibitor
ASC25_RS05420	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ASC25_RS05445	COG0248	Ppx GppA phosphatase
ASC25_RS05455	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ASC25_RS05465	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ASC25_RS05470	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
ASC25_RS05475	COG1534	Rna-binding protein
ASC25_RS05505	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ASC25_RS05520	COG1295	ribonuclease BN
ASC25_RS05530	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ASC25_RS05535	COG0745	RESPONSE REGULATOR receiver
ASC25_RS05540	COG2205	protein histidine kinase activity
ASC25_RS05575	COG1022	Amp-dependent synthetase and ligase
ASC25_RS05590	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ASC25_RS05595	COG1028	Short-chain dehydrogenase reductase Sdr
ASC25_RS05605	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ASC25_RS05620	COG1136	(ABC) transporter
ASC25_RS05625	COG0084	hydrolase, TatD family'
ASC25_RS05655	COG0658	competence protein
ASC25_RS05655	COG2333	competence protein COMEC
ASC25_RS05665	COG0613	PHP domain protein
ASC25_RS05680	COG3539	Fimbrial protein
ASC25_RS05685	COG0281	malic enzyme
ASC25_RS05685	COG0280	phosphate acetyltransferase
ASC25_RS05695	COG1522	sequence-specific DNA binding
ASC25_RS05705	COG0567	Dehydrogenase, E1 component
ASC25_RS05710	COG0508	dehydrogenase complex catalyzes the overall conversion of
ASC25_RS05715	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ASC25_RS05720	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ASC25_RS05725	COG1028	Short-chain dehydrogenase reductase Sdr
ASC25_RS05730	COG0583	DNA-binding transcription factor activity
ASC25_RS05740	COG3181	Tripartite tricarboxylate transporter family receptor
ASC25_RS05765	COG0180	Tryptophanyl-tRNA synthetase
ASC25_RS05770	COG2183	response to ionizing radiation
ASC25_RS05775	COG1199	ATP-dependent helicase activity
ASC25_RS05785	COG0564	pseudouridine synthase activity
ASC25_RS05795	COG3243	poly(R)-hydroxyalkanoic acid synthase
ASC25_RS05800	COG1028	Short-chain dehydrogenase reductase Sdr
ASC25_RS05805	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
ASC25_RS05820	COG0672	)-iron permease
ASC25_RS05860	COG0583	DNA-binding transcription factor activity
ASC25_RS05870	COG2814	Major facilitator Superfamily
ASC25_RS05885	COG1619	proteins homologs of microcin C7 resistance protein MccF
ASC25_RS05900	COG2084	Dehydrogenase
ASC25_RS05905	COG3181	Tripartite tricarboxylate transporter family receptor
ASC25_RS05930	COG2988	succinylglutamate desuccinylase activity
ASC25_RS05955	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ASC25_RS05960	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ASC25_RS05960	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ASC25_RS05965	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ASC25_RS05970	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ASC25_RS05970	COG0047	phosphoribosylformylglycinamidine synthase activity
ASC25_RS05975	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
ASC25_RS05975	COG3210	domain, Protein
ASC25_RS05975	COG3064	Membrane
ASC25_RS06000	COG0235	Class ii aldolase
ASC25_RS06005	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ASC25_RS06010	COG0720	synthase
ASC25_RS06015	COG0602	queuosine metabolic process
ASC25_RS06040	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ASC25_RS06075	COG3181	Tripartite tricarboxylate transporter family receptor
ASC25_RS06105	COG3842	ATPase activity
ASC25_RS06115	COG0395	ABC-type sugar transport system, permease component
ASC25_RS06145	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ASC25_RS06150	COG0420	3'-5' exonuclease activity
ASC25_RS06195	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ASC25_RS06195	COG0519	Catalyzes the synthesis of GMP from XMP
ASC25_RS06210	COG3550	peptidyl-serine autophosphorylation
ASC25_RS06220	COG0477	Major facilitator Superfamily
ASC25_RS06235	COG1228	amidohydrolase
ASC25_RS06245	COG1116	anion transmembrane transporter activity
ASC25_RS06250	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ASC25_RS06290	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ASC25_RS06310	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ASC25_RS06340	COG2814	Major facilitator Superfamily
ASC25_RS06355	COG1280	lysine exporter protein (LysE YggA)
ASC25_RS06370	COG0747	negative chemotaxis
ASC25_RS06375	COG0601	transmembrane transport
ASC25_RS06380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASC25_RS06385	COG4172	Belongs to the ABC transporter superfamily
ASC25_RS06390	COG1609	Transcriptional regulator
ASC25_RS06420	COG0586	Pfam SNARE associated Golgi protein
ASC25_RS06435	COG0500	methyltransferase
ASC25_RS06450	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ASC25_RS06460	COG0756	dUTP diphosphatase activity
ASC25_RS06475	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ASC25_RS06480	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ASC25_RS06485	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ASC25_RS06490	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ASC25_RS06490	COG0072	phenylalanine-tRNA ligase activity
ASC25_RS06495	COG0776	regulation of translation
ASC25_RS06565	COG0540	Belongs to the ATCase OTCase family
ASC25_RS06570	COG2974	May be involved in recombination
ASC25_RS06580	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ASC25_RS06585	COG0583	DNA-binding transcription factor activity
ASC25_RS06605	COG1028	Short-chain dehydrogenase reductase Sdr
ASC25_RS06620	COG3842	ATPase activity
ASC25_RS06625	COG1024	Enoyl-CoA hydratase
ASC25_RS06625	COG1250	3-hydroxyacyl-CoA dehydrogenase
ASC25_RS06645	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ASC25_RS06650	COG2137	regulation of response to DNA damage stimulus
ASC25_RS06660	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ASC25_RS06670	COG0045	succinate-CoA ligase (ADP-forming) activity
ASC25_RS06675	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ASC25_RS06680	COG0861	Integral membrane protein TerC family
ASC25_RS06685	COG0861	Integral membrane protein TerC family
ASC25_RS06690	COG0181	hydroxymethylbilane synthase activity
ASC25_RS06750	COG4964	Belongs to the GSP D family
ASC25_RS06780	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ASC25_RS06790	COG0583	DNA-binding transcription factor activity
ASC25_RS06800	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ASC25_RS06805	COG4311	Sarcosine oxidase, delta subunit
ASC25_RS06810	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ASC25_RS06810	COG0446	pyridine nucleotide-disulphide oxidoreductase
ASC25_RS06845	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ASC25_RS06850	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ASC25_RS06855	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ASC25_RS06860	COG0735	belongs to the Fur family
ASC25_RS06865	COG0497	DNA recombination
ASC25_RS06870	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ASC25_RS06875	COG1420	regulation of RNA biosynthetic process
ASC25_RS06880	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ASC25_RS06890	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ASC25_RS06900	COG0443	Heat shock 70 kDa protein
ASC25_RS06910	COG0612	Peptidase, M16
ASC25_RS06930	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ASC25_RS06975	COG0745	RESPONSE REGULATOR receiver
ASC25_RS06985	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
ASC25_RS06990	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
ASC25_RS06995	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ASC25_RS07010	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ASC25_RS07030	COG1193	negative regulation of DNA recombination
ASC25_RS07035	COG0492	ferredoxin-NADP+ reductase activity
ASC25_RS07040	COG1674	ftsk spoiiie
ASC25_RS07045	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ASC25_RS07050	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ASC25_RS07055	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ASC25_RS07080	COG3706	GGDEF domain
ASC25_RS07100	COG2814	Major facilitator Superfamily
ASC25_RS07130	COG3486	L-lysine 6-monooxygenase (NADPH) activity
ASC25_RS07145	COG1028	Short-chain dehydrogenase reductase Sdr
ASC25_RS07155	COG3022	response to hydroperoxide
ASC25_RS07165	COG1289	transmembrane transporter activity
ASC25_RS07185	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ASC25_RS07195	COG2197	response regulator
ASC25_RS07200	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ASC25_RS07205	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ASC25_RS07210	COG0189	ligase activity
ASC25_RS07220	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASC25_RS07225	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ASC25_RS07235	COG1764	response to oxidative stress
ASC25_RS07240	COG2423	ornithine cyclodeaminase activity
ASC25_RS07250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASC25_RS07255	COG0765	amino acid transport
ASC25_RS07260	COG0765	amino acid transport
ASC25_RS07265	COG1126	abc transporter atp-binding protein
ASC25_RS07320	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ASC25_RS07330	COG2944	sequence-specific DNA binding
ASC25_RS07340	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ASC25_RS07345	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ASC25_RS07350	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ASC25_RS07355	COG0009	L-threonylcarbamoyladenylate synthase
ASC25_RS07360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASC25_RS07365	COG1414	Transcriptional regulator
ASC25_RS07380	COG0765	amino acid transport
ASC25_RS07385	COG1126	abc transporter atp-binding protein
ASC25_RS07390	COG0028	Belongs to the TPP enzyme family
ASC25_RS07405	COG0028	Belongs to the TPP enzyme family
ASC25_RS07410	COG0583	DNA-binding transcription factor activity
ASC25_RS07415	COG4974	Belongs to the 'phage' integrase family
ASC25_RS07420	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ASC25_RS07425	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
ASC25_RS07440	COG1686	Belongs to the peptidase S11 family
ASC25_RS07450	COG2814	Major facilitator Superfamily
ASC25_RS07460	COG1074	ATP-dependent DNA helicase activity
ASC25_RS07475	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ASC25_RS07480	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ASC25_RS07485	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ASC25_RS07505	COG2321	neutral zinc metallopeptidase
ASC25_RS07510	COG0009	L-threonylcarbamoyladenylate synthase
ASC25_RS07555	COG3360	Dodecin
ASC25_RS07560	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ASC25_RS07565	COG2850	peptidyl-arginine hydroxylation
ASC25_RS07570	COG3539	Fimbrial protein
ASC25_RS07575	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
ASC25_RS07580	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ASC25_RS07600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASC25_RS07605	COG0765	amino acid transport
ASC25_RS07610	COG1126	abc transporter atp-binding protein
ASC25_RS07615	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ASC25_RS07620	COG1758	RNA polymerase activity
ASC25_RS07625	COG0194	GDP metabolic process
ASC25_RS07630	COG3258	Cytochrome c
ASC25_RS07635	COG2863	cytochrome
ASC25_RS07640	COG1028	Short-chain dehydrogenase reductase Sdr
ASC25_RS07645	COG0791	NLP P60 protein
ASC25_RS07650	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ASC25_RS07670	COG1561	YicC-like family, N-terminal region
ASC25_RS07675	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ASC25_RS07690	COG0840	transmembrane signaling receptor activity
ASC25_RS07695	COG2200	EAL domain
ASC25_RS07695	COG2199	diguanylate cyclase activity
ASC25_RS07700	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ASC25_RS07710	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ASC25_RS07715	COG0174	glutamine synthetase
ASC25_RS07725	COG2204	response regulator
ASC25_RS07730	COG0583	DNA-binding transcription factor activity
ASC25_RS07735	COG1741	Belongs to the pirin family
ASC25_RS07740	COG1741	Belongs to the pirin family
ASC25_RS07750	COG3842	ATPase activity
ASC25_RS07755	COG1178	ABC-type Fe3 transport system permease component
ASC25_RS07760	COG1840	ABC-type Fe3 transport system, periplasmic component
ASC25_RS07770	COG0583	DNA-binding transcription factor activity
ASC25_RS07780	COG0656	L-ascorbic acid biosynthetic process
ASC25_RS07795	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ASC25_RS07800	COG0583	DNA-binding transcription factor activity
ASC25_RS07815	COG0783	Belongs to the Dps family
ASC25_RS07835	COG0463	Glycosyl transferase, family 2
ASC25_RS07855	COG0438	transferase activity, transferring glycosyl groups
ASC25_RS07870	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ASC25_RS07895	COG0300	oxidoreductase activity
ASC25_RS07940	COG0861	Integral membrane protein TerC family
ASC25_RS07945	COG1028	Short-chain dehydrogenase reductase Sdr
ASC25_RS07965	COG0714	Associated with various cellular activities
ASC25_RS08000	COG3119	arylsulfatase activity
ASC25_RS08025	COG2197	response regulator
ASC25_RS08035	COG2944	sequence-specific DNA binding
ASC25_RS08040	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
ASC25_RS08045	COG0625	glutathione transferase activity
ASC25_RS08075	COG0179	Fumarylacetoacetate (FAA) hydrolase
ASC25_RS08080	COG1028	Short-chain dehydrogenase reductase Sdr
ASC25_RS08125	COG0431	NADPH-dependent FMN reductase
ASC25_RS08155	COG1028	Short-chain dehydrogenase reductase Sdr
ASC25_RS08160	COG0583	DNA-binding transcription factor activity
ASC25_RS08175	COG3181	Tripartite tricarboxylate transporter family receptor
ASC25_RS08180	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ASC25_RS08180	COG2111	Na H antiporter
ASC25_RS08185	COG1006	Multisubunit Na H antiporter MnhC subunit
ASC25_RS08190	COG0651	ATP synthesis coupled electron transport
ASC25_RS08195	COG1863	multisubunit Na H antiporter MnhE subunit
ASC25_RS08200	COG2212	antiporter activity
ASC25_RS08225	COG0590	tRNA wobble adenosine to inosine editing
ASC25_RS08230	COG1619	proteins homologs of microcin C7 resistance protein MccF
ASC25_RS08235	COG1024	Enoyl-CoA hydratase
ASC25_RS08250	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ASC25_RS08255	COG0488	(ABC) transporter
ASC25_RS08290	COG1017	nitric oxide dioxygenase activity
ASC25_RS08290	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ASC25_RS08295	COG1959	2 iron, 2 sulfur cluster binding
ASC25_RS08300	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ASC25_RS08320	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ASC25_RS08325	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ASC25_RS08330	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ASC25_RS08335	COG0084	hydrolase, TatD family'
ASC25_RS08350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASC25_RS08360	COG1126	abc transporter atp-binding protein
ASC25_RS08365	COG0010	Belongs to the arginase family
ASC25_RS08370	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ASC25_RS08375	COG1012	belongs to the aldehyde dehydrogenase family
ASC25_RS08385	COG0028	Belongs to the TPP enzyme family
ASC25_RS08395	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ASC25_RS08395	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ASC25_RS08405	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ASC25_RS08420	COG3189	MarR family transcriptional regulator
ASC25_RS08425	COG2010	Cytochrome c
ASC25_RS08450	COG4336	lyase activity
ASC25_RS08460	COG2205	protein histidine kinase activity
ASC25_RS08460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASC25_RS08465	COG2197	response regulator
ASC25_RS08470	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
ASC25_RS08470	COG3210	domain, Protein
ASC25_RS08470	COG3064	Membrane
ASC25_RS08485	COG3121	Chaperone
ASC25_RS08490	COG3188	usher protein
ASC25_RS08495	COG3539	Fimbrial protein
ASC25_RS08500	COG2831	hemolysin activation secretion protein
ASC25_RS08515	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ASC25_RS08540	COG0583	DNA-binding transcription factor activity
ASC25_RS08565	COG0668	transmembrane transport
ASC25_RS08585	COG0483	inositol monophosphate 1-phosphatase activity
ASC25_RS08590	COG1253	flavin adenine dinucleotide binding
ASC25_RS08595	COG1968	undecaprenyl-diphosphatase activity
ASC25_RS08600	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ASC25_RS08615	COG0215	cysteine-tRNA ligase activity
ASC25_RS08625	COG0825	malonyl-CoA metabolic process
ASC25_RS08635	COG0037	tRNA processing
ASC25_RS08640	COG0527	aspartate kinase activity
ASC25_RS08665	COG1250	3-hydroxyacyl-CoA dehydrogenase
ASC25_RS08670	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ASC25_RS08670	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ASC25_RS08685	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ASC25_RS08690	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
ASC25_RS08695	COG1028	Short-chain dehydrogenase reductase Sdr
ASC25_RS08705	COG0583	DNA-binding transcription factor activity
ASC25_RS08735	COG3842	ATPase activity
ASC25_RS08745	COG1902	pentaerythritol trinitrate reductase activity
ASC25_RS08745	COG0446	pyridine nucleotide-disulphide oxidoreductase
ASC25_RS08750	COG1414	Transcriptional regulator
ASC25_RS08755	COG1832	CoA-binding protein
ASC25_RS08765	COG0251	oxidation-reduction process
ASC25_RS08790	COG1902	pentaerythritol trinitrate reductase activity
ASC25_RS08800	COG1215	transferase activity, transferring glycosyl groups
ASC25_RS08805	COG1649	PFAM Uncharacterised BCR, COG1649
ASC25_RS08805	COG0726	polysaccharide deacetylase
ASC25_RS08825	COG1846	Transcriptional regulator
ASC25_RS08840	COG3468	outer membrane autotransporter barrel domain protein
ASC25_RS08845	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ASC25_RS08855	COG0556	nucleotide-excision repair
ASC25_RS08860	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ASC25_RS08870	COG1104	cysteine desulfurase activity
ASC25_RS08875	COG0822	iron-sulfur transferase activity
ASC25_RS08880	COG0316	Belongs to the HesB IscA family
ASC25_RS08885	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ASC25_RS08890	COG0443	Heat shock 70 kDa protein
ASC25_RS08895	COG0633	Ferredoxin
ASC25_RS08915	COG1024	Enoyl-CoA hydratase
ASC25_RS08935	COG3395	kinase activity
ASC25_RS08940	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ASC25_RS08955	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ASC25_RS08965	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ASC25_RS08990	COG0747	negative chemotaxis
ASC25_RS08995	COG0601	transmembrane transport
ASC25_RS09000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASC25_RS09005	COG4172	Belongs to the ABC transporter superfamily
ASC25_RS09010	COG0154	amidase activity
ASC25_RS09055	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ASC25_RS09060	COG0425	Belongs to the sulfur carrier protein TusA family
ASC25_RS09070	COG0228	four-way junction DNA binding
ASC25_RS09075	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ASC25_RS09080	COG0336	Belongs to the RNA methyltransferase TrmD family
ASC25_RS09085	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ASC25_RS09105	COG0642	Histidine kinase
ASC25_RS09120	COG0525	valine-tRNA ligase activity
ASC25_RS09125	COG0105	UTP biosynthetic process
ASC25_RS09130	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ASC25_RS09140	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ASC25_RS09145	COG0124	histidyl-tRNA synthetase
ASC25_RS09150	COG2976	Protein conserved in bacteria
ASC25_RS09155	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ASC25_RS09160	COG1160	GTP binding
ASC25_RS09165	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ASC25_RS09170	COG1923	regulation of RNA biosynthetic process
ASC25_RS09175	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ASC25_RS09180	COG0330	HflC and HflK could
ASC25_RS09185	COG0330	HflC and HflK could
ASC25_RS09190	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ASC25_RS09195	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ASC25_RS09200	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ASC25_RS09205	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ASC25_RS09215	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ASC25_RS09250	COG0628	permease
ASC25_RS09255	COG0842	Transport permease protein
ASC25_RS09260	COG1131	(ABC) transporter
ASC25_RS09330	COG0156	8-amino-7-oxononanoate synthase activity
ASC25_RS09340	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ASC25_RS09340	COG4106	trans-aconitate 2-methyltransferase activity
ASC25_RS09345	COG1380	Effector of murein hydrolase LrgA
ASC25_RS09365	COG3284	Transcriptional regulator
ASC25_RS09370	COG1012	belongs to the aldehyde dehydrogenase family
ASC25_RS09385	COG2733	membrane
ASC25_RS09390	COG0583	DNA-binding transcription factor activity
ASC25_RS09395	COG0384	phenazine biosynthesis protein PhzF
ASC25_RS09400	COG5507	3-demethylubiquinone-9 3-methyltransferase
ASC25_RS09405	COG2169	Transcriptional regulator
ASC25_RS09435	COG0659	secondary active sulfate transmembrane transporter activity
ASC25_RS09460	COG1132	(ABC) transporter
ASC25_RS09505	COG2207	Transcriptional regulator
ASC25_RS09640	COG2346	COG2346, Truncated hemoglobins
ASC25_RS09685	COG0183	Belongs to the thiolase family
ASC25_RS09700	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ASC25_RS09705	COG0633	Ferredoxin
ASC25_RS09715	COG1024	Enoyl-CoA hydratase
ASC25_RS09725	COG4638	Rieske (2fe-2S)
ASC25_RS09735	COG0559	Belongs to the binding-protein-dependent transport system permease family
ASC25_RS09755	COG2224	Isocitrate lyase
ASC25_RS09760	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ASC25_RS09760	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ASC25_RS09775	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ASC25_RS09780	COG0322	excinuclease ABC activity
ASC25_RS09785	COG1472	Belongs to the glycosyl hydrolase 3 family
ASC25_RS09790	COG0736	holo-[acyl-carrier-protein] synthase activity
ASC25_RS09795	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ASC25_RS09805	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ASC25_RS09810	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASC25_RS09835	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
ASC25_RS09850	COG2032	superoxide dismutase activity
ASC25_RS09865	COG1024	Enoyl-CoA hydratase
ASC25_RS09875	COG1802	Transcriptional regulator
ASC25_RS09885	COG0183	Belongs to the thiolase family
ASC25_RS09890	COG1942	4-Oxalocrotonate Tautomerase
ASC25_RS09900	COG4176	ABC-type proline glycine betaine transport system permease component
ASC25_RS09915	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ASC25_RS09920	COG2814	Major facilitator Superfamily
ASC25_RS09925	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ASC25_RS09930	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ASC25_RS09960	COG2814	Major facilitator Superfamily
ASC25_RS09965	COG0495	leucyl-tRNA aminoacylation
ASC25_RS09980	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ASC25_RS09990	COG0154	amidase activity
ASC25_RS09995	COG1250	3-hydroxyacyl-CoA dehydrogenase
ASC25_RS10050	COG0427	acetyl-CoA hydrolase
ASC25_RS10055	COG0583	DNA-binding transcription factor activity
ASC25_RS10075	COG0730	response to heat
ASC25_RS10080	COG0697	spore germination
ASC25_RS10115	COG2885	chlorophyll binding
ASC25_RS10140	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ASC25_RS10145	COG3384	dioxygenase
ASC25_RS10160	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ASC25_RS10165	COG3474	cytochrome
ASC25_RS10175	COG1595	DNA-templated transcription, initiation
ASC25_RS10190	COG2204	response regulator
ASC25_RS10230	COG4964	Belongs to the GSP D family
ASC25_RS10280	COG1846	Transcriptional regulator
ASC25_RS10285	COG4172	Belongs to the ABC transporter superfamily
ASC25_RS10290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASC25_RS10295	COG0601	transmembrane transport
ASC25_RS10300	COG0747	negative chemotaxis
ASC25_RS10310	COG0598	Magnesium transport protein CorA
ASC25_RS10315	COG0210	DNA helicase
ASC25_RS10330	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ASC25_RS10335	COG1012	belongs to the aldehyde dehydrogenase family
ASC25_RS10340	COG0483	inositol monophosphate 1-phosphatase activity
ASC25_RS10345	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ASC25_RS10355	COG1045	serine acetyltransferase
ASC25_RS10360	COG0166	Belongs to the GPI family
ASC25_RS10375	COG2197	response regulator
ASC25_RS10395	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ASC25_RS10410	COG1960	acyl-CoA dehydrogenase activity
ASC25_RS10415	COG1028	Short-chain dehydrogenase reductase Sdr
ASC25_RS10420	COG0183	Belongs to the thiolase family
ASC25_RS10430	COG1024	Enoyl-CoA hydratase
ASC25_RS10445	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ASC25_RS10450	COG0583	DNA-binding transcription factor activity
ASC25_RS10455	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ASC25_RS10460	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ASC25_RS10465	COG0740	serine-type endopeptidase activity
ASC25_RS10470	COG0544	peptidyl-prolyl cis-trans isomerase activity
ASC25_RS10490	COG1278	Cold shock
ASC25_RS10525	COG2171	N-acyltransferase activity
ASC25_RS10530	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ASC25_RS10535	COG2890	protein-(glutamine-N5) methyltransferase activity
ASC25_RS10540	COG0488	(ABC) transporter
ASC25_RS10545	COG4771	TonB-dependent receptor
ASC25_RS10550	COG0210	DNA helicase
ASC25_RS10570	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ASC25_RS10575	COG0196	riboflavin kinase activity
ASC25_RS10580	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ASC25_RS10585	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ASC25_RS10590	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ASC25_RS10600	COG1522	sequence-specific DNA binding
ASC25_RS10620	COG2951	lytic endotransglycosylase activity
ASC25_RS10625	COG2833	Protein of unknown function (DUF455)
ASC25_RS10645	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ASC25_RS10645	COG0189	ligase activity
ASC25_RS10650	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ASC25_RS10650	COG1181	Belongs to the D-alanine--D-alanine ligase family
ASC25_RS10655	COG3237	CsbD-like
ASC25_RS10665	COG2823	Periplasmic or secreted lipoprotein
ASC25_RS10675	COG4181	ATPase activity
ASC25_RS10685	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ASC25_RS10690	COG0584	glycerophosphoryl diester phosphodiesterase
ASC25_RS10695	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ASC25_RS10705	COG0678	peroxiredoxin activity
ASC25_RS10705	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ASC25_RS10715	COG0789	Transcriptional regulator
ASC25_RS10720	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ASC25_RS10750	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ASC25_RS10755	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ASC25_RS10765	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ASC25_RS10770	COG2252	PERMEase
ASC25_RS10780	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ASC25_RS10815	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ASC25_RS10820	COG2358	TRAP transporter, solute receptor (TAXI family
ASC25_RS10855	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ASC25_RS10860	COG1366	Belongs to the anti-sigma-factor antagonist family
ASC25_RS10865	COG2172	sigma factor antagonist activity
ASC25_RS10870	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ASC25_RS10880	COG2770	Histidine kinase
ASC25_RS10880	COG2208	phosphoserine phosphatase activity
ASC25_RS10905	COG1595	DNA-templated transcription, initiation
ASC25_RS10920	COG4792	protein secretion
ASC25_RS10925	COG4791	protein targeting
ASC25_RS10930	COG4794	Type iii secretion
ASC25_RS10935	COG4790	Type iii secretion
ASC25_RS10970	COG4669	(LipO)protein
ASC25_RS11035	COG4789	Type iii secretion
ASC25_RS11065	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ASC25_RS11070	COG0840	transmembrane signaling receptor activity
ASC25_RS11075	COG2233	PERMEase
ASC25_RS11095	COG0492	ferredoxin-NADP+ reductase activity
ASC25_RS11100	COG1840	ABC-type Fe3 transport system, periplasmic component
ASC25_RS11105	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ASC25_RS11110	COG1178	ABC-type Fe3 transport system permease component
ASC25_RS11115	COG3842	ATPase activity
ASC25_RS11120	COG0583	DNA-binding transcription factor activity
ASC25_RS11140	COG0501	Belongs to the peptidase M48B family
ASC25_RS11150	COG0697	spore germination
ASC25_RS11160	COG1846	Transcriptional regulator
ASC25_RS11170	COG1566	PFAM secretion protein HlyD family protein
ASC25_RS11175	COG2814	Major facilitator Superfamily
ASC25_RS11180	COG0473	3-isopropylmalate dehydrogenase activity
ASC25_RS11190	COG0747	negative chemotaxis
ASC25_RS11200	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASC25_RS11215	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ASC25_RS11240	COG1012	belongs to the aldehyde dehydrogenase family
ASC25_RS11250	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ASC25_RS11255	COG1115	amino acid carrier protein
ASC25_RS11260	COG0433	COG0433 Predicted ATPase
ASC25_RS11265	COG0217	transcriptional regulatory protein
ASC25_RS11270	COG0151	Belongs to the GarS family
ASC25_RS11275	COG0408	coproporphyrinogen oxidase activity
ASC25_RS11280	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ASC25_RS11285	COG0799	negative regulation of ribosome biogenesis
ASC25_RS11290	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ASC25_RS11295	COG0424	maF-like protein
ASC25_RS11300	COG3468	outer membrane autotransporter barrel domain protein
ASC25_RS11340	COG1530	ribonuclease E activity
ASC25_RS11345	COG0077	Prephenate dehydratase
ASC25_RS11360	COG1132	(ABC) transporter
ASC25_RS11365	COG0859	PFAM glycosyl transferase family 9
ASC25_RS11390	COG2194	sulfuric ester hydrolase activity
ASC25_RS11395	COG0438	transferase activity, transferring glycosyl groups
ASC25_RS11400	COG0463	Glycosyl transferase, family 2
ASC25_RS11405	COG0726	polysaccharide deacetylase
ASC25_RS11410	COG0438	transferase activity, transferring glycosyl groups
ASC25_RS11425	COG1643	Atp-dependent helicase
ASC25_RS11430	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ASC25_RS11430	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ASC25_RS11435	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
ASC25_RS11445	COG0704	Plays a role in the regulation of phosphate uptake
ASC25_RS11450	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ASC25_RS11455	COG1960	acyl-CoA dehydrogenase activity
ASC25_RS11480	COG1177	transmembrane transport
ASC25_RS11485	COG1176	ABC-type spermidine putrescine transport system, permease component I
ASC25_RS11490	COG3842	ATPase activity
ASC25_RS11495	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ASC25_RS11510	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
ASC25_RS11515	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ASC25_RS11525	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ASC25_RS11525	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ASC25_RS11545	COG0372	Belongs to the citrate synthase family
ASC25_RS11550	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
ASC25_RS11555	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ASC25_RS11560	COG1053	succinate dehydrogenase
ASC25_RS11565	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ASC25_RS11570	COG2009	succinate dehydrogenase
ASC25_RS11575	COG2188	Transcriptional regulator
ASC25_RS11580	COG0039	L-malate dehydrogenase activity
ASC25_RS11610	COG1981	membrane
ASC25_RS11635	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ASC25_RS11645	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ASC25_RS11675	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ASC25_RS11680	COG0148	phosphopyruvate hydratase activity
ASC25_RS11690	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ASC25_RS11695	COG0504	CTP synthase activity
ASC25_RS11720	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASC25_RS11730	COG0747	negative chemotaxis
ASC25_RS11735	COG4172	Belongs to the ABC transporter superfamily
ASC25_RS11740	COG1446	asparaginase
ASC25_RS11770	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ASC25_RS11785	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
ASC25_RS11790	COG0697	spore germination
ASC25_RS11795	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ASC25_RS11805	COG3193	protein, possibly involved in utilization of glycolate and propanediol
ASC25_RS11810	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ASC25_RS11815	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ASC25_RS11820	COG0791	NLP P60 protein
ASC25_RS11835	COG0583	DNA-binding transcription factor activity
ASC25_RS11850	COG0583	DNA-binding transcription factor activity
ASC25_RS11860	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ASC25_RS11875	COG0670	Belongs to the BI1 family
ASC25_RS11880	COG3181	Tripartite tricarboxylate transporter family receptor
ASC25_RS11890	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ASC25_RS11900	COG1381	Involved in DNA repair and RecF pathway recombination
ASC25_RS11905	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ASC25_RS11910	COG0571	ribonuclease III activity
ASC25_RS11915	COG0681	Belongs to the peptidase S26 family
ASC25_RS11920	COG0481	GTPase activity
ASC25_RS11925	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ASC25_RS11950	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ASC25_RS11955	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ASC25_RS11970	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ASC25_RS11975	COG0416	fatty acid biosynthetic process
ASC25_RS11980	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ASC25_RS11985	COG1399	metal-binding, possibly nucleic acid-binding protein
ASC25_RS11990	COG0424	maF-like protein
ASC25_RS12000	COG3023	N-Acetylmuramoyl-L-alanine amidase
ASC25_RS12005	COG1289	transmembrane transporter activity
ASC25_RS12015	COG3022	response to hydroperoxide
ASC25_RS12030	COG0135	phosphoribosylanthranilate isomerase activity
ASC25_RS12045	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ASC25_RS12050	COG0101	tRNA pseudouridine synthase activity
ASC25_RS12060	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ASC25_RS12065	COG0473	3-isopropylmalate dehydrogenase activity
ASC25_RS12070	COG0066	3-isopropylmalate dehydratase activity
ASC25_RS12075	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ASC25_RS12085	COG1122	ATPase activity
ASC25_RS12115	COG0437	4 iron, 4 sulfur cluster binding
ASC25_RS12120	COG3383	formate dehydrogenase (NAD+) activity
ASC25_RS12120	COG0243	molybdopterin cofactor binding
ASC25_RS12150	COG0489	protein tyrosine kinase activity
ASC25_RS12155	COG0746	molybdenum cofactor guanylyltransferase activity
ASC25_RS12160	COG0303	'Molybdopterin
ASC25_RS12165	COG1763	Mo-molybdopterin cofactor biosynthetic process
ASC25_RS12175	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ASC25_RS12180	COG5001	Diguanylate cyclase
ASC25_RS12200	COG3842	ATPase activity
ASC25_RS12210	COG0406	alpha-ribazole phosphatase activity
ASC25_RS12220	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ASC25_RS12225	COG0505	Belongs to the CarA family
ASC25_RS12230	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ASC25_RS12260	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ASC25_RS12265	COG1960	acyl-CoA dehydrogenase activity
ASC25_RS12275	COG2867	negative regulation of translational initiation
ASC25_RS12285	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ASC25_RS12290	COG3706	GGDEF domain
ASC25_RS12295	COG0330	HflC and HflK could
ASC25_RS12310	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ASC25_RS12310	COG0519	Catalyzes the synthesis of GMP from XMP
ASC25_RS12320	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
ASC25_RS12325	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ASC25_RS12330	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ASC25_RS12335	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ASC25_RS12345	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ASC25_RS12350	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ASC25_RS12355	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
ASC25_RS12360	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ASC25_RS12365	COG0750	zinc metalloprotease
ASC25_RS12370	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ASC25_RS12380	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ASC25_RS12385	COG0233	cytoplasmic translational termination
ASC25_RS12390	COG0528	UMP kinase activity
ASC25_RS12395	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ASC25_RS12400	COG0052	Belongs to the universal ribosomal protein uS2 family
ASC25_RS12405	COG0024	Methionine aminopeptidase
ASC25_RS12410	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
ASC25_RS12440	COG0285	dihydrofolate synthase activity
ASC25_RS12475	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ASC25_RS12485	COG1677	Flagellar hook-basal body complex protein FliE
ASC25_RS12495	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ASC25_RS12505	COG1157	protein secretion by the type III secretion system
ASC25_RS12530	COG1580	Controls the rotational direction of flagella during chemotaxis
ASC25_RS12550	COG1338	Plays a role in the flagellum-specific transport system
ASC25_RS12570	COG0840	transmembrane signaling receptor activity
ASC25_RS12575	COG0840	transmembrane signaling receptor activity
ASC25_RS12580	COG0840	transmembrane signaling receptor activity
ASC25_RS12590	COG1256	bacterial-type flagellum assembly
ASC25_RS12600	COG1706	bacterial-type flagellum-dependent cell motility
ASC25_RS12605	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
ASC25_RS12620	COG1749	Flagellar hook protein flgE
ASC25_RS12630	COG1558	bacterial-type flagellum-dependent cell motility
ASC25_RS12635	COG1815	bacterial-type flagellum-dependent cell motility
ASC25_RS12675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASC25_RS12680	COG0765	amino acid transport
ASC25_RS12685	COG1126	abc transporter atp-binding protein
ASC25_RS12700	COG4948	Mandelate Racemase Muconate Lactonizing
ASC25_RS12705	COG3181	Tripartite tricarboxylate transporter family receptor
ASC25_RS12715	COG0066	3-isopropylmalate dehydratase activity
ASC25_RS12730	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ASC25_RS12740	COG3181	Tripartite tricarboxylate transporter family receptor
ASC25_RS12750	COG1802	Transcriptional regulator
ASC25_RS12765	COG0583	DNA-binding transcription factor activity
ASC25_RS12785	COG1695	Transcriptional regulator
ASC25_RS12795	COG3568	Endonuclease Exonuclease Phosphatase
ASC25_RS12800	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ASC25_RS12815	COG0392	lysyltransferase activity
ASC25_RS12855	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ASC25_RS12865	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ASC25_RS12885	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
ASC25_RS12915	COG0667	Aldo Keto reductase
ASC25_RS12930	COG2259	Doxx family
ASC25_RS12965	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ASC25_RS12985	COG0386	Belongs to the glutathione peroxidase family
ASC25_RS12990	COG0625	glutathione transferase activity
ASC25_RS13015	COG0688	phosphatidylethanolamine metabolic process
ASC25_RS13025	COG1464	Belongs to the NlpA lipoprotein family
ASC25_RS13040	COG2363	Small membrane protein
ASC25_RS13065	COG3842	ATPase activity
ASC25_RS13070	COG0395	ABC-type sugar transport system, permease component
ASC25_RS13075	COG1175	transmembrane transport
ASC25_RS13080	COG1653	transport
ASC25_RS13090	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ASC25_RS13105	COG0559	Belongs to the binding-protein-dependent transport system permease family
ASC25_RS13125	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ASC25_RS13140	COG0697	spore germination
ASC25_RS13155	COG2311	Membrane
ASC25_RS13180	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ASC25_RS13190	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ASC25_RS13195	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ASC25_RS13200	COG1760	l-serine dehydratase
ASC25_RS13205	COG1283	sodium-dependent phosphate transmembrane transporter activity
ASC25_RS13210	COG0412	Dienelactone hydrolase
ASC25_RS13225	COG1611	Belongs to the LOG family
ASC25_RS13245	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ASC25_RS13250	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ASC25_RS13255	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ASC25_RS13260	COG0195	Participates in both transcription termination and antitermination
ASC25_RS13260	COG2251	uridine kinase activity
ASC25_RS13265	COG0779	Required for maturation of 30S ribosomal subunits
ASC25_RS13270	COG1187	pseudouridine synthase activity
ASC25_RS13275	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ASC25_RS13285	COG0583	DNA-binding transcription factor activity
ASC25_RS13295	COG0523	cobalamin synthesis protein
ASC25_RS13315	COG0625	glutathione transferase activity
ASC25_RS13320	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ASC25_RS13325	COG1047	Peptidyl-prolyl cis-trans
ASC25_RS13330	COG2003	Belongs to the UPF0758 family
ASC25_RS13335	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
ASC25_RS13340	COG3483	tryptophan 2,3-dioxygenase activity
ASC25_RS13345	COG0254	rRNA binding
ASC25_RS13355	COG0534	Mate efflux family protein
ASC25_RS13375	COG2304	oxidoreductase activity
ASC25_RS13395	COG1028	Short-chain dehydrogenase reductase Sdr
ASC25_RS13400	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ASC25_RS13405	COG1562	ergosterol biosynthetic process
ASC25_RS13410	COG1562	ergosterol biosynthetic process
ASC25_RS13415	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
ASC25_RS13415	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
ASC25_RS13420	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ASC25_RS13430	COG0842	Transport permease protein
ASC25_RS13435	COG1131	(ABC) transporter
ASC25_RS13455	COG1477	protein flavinylation
ASC25_RS13470	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
ASC25_RS13485	COG5564	TIM-barrel signal transduction protein
ASC25_RS13490	COG5441	Belongs to the UPF0261 family
ASC25_RS13500	COG3468	outer membrane autotransporter barrel domain protein
ASC25_RS13505	COG3468	outer membrane autotransporter barrel domain protein
ASC25_RS13520	COG0542	response to heat
ASC25_RS13525	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ASC25_RS13540	COG0494	nUDIX hydrolase
ASC25_RS13545	COG3530	Putative quorum-sensing-regulated virulence factor
ASC25_RS13555	COG1595	DNA-templated transcription, initiation
ASC25_RS13560	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ASC25_RS13595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASC25_RS13600	COG0765	amino acid transport
ASC25_RS13605	COG0765	amino acid transport
ASC25_RS13630	COG3539	Fimbrial protein
ASC25_RS13640	COG2050	protein possibly involved in aromatic compounds catabolism
ASC25_RS13645	COG1024	Enoyl-CoA hydratase
ASC25_RS13650	COG1012	belongs to the aldehyde dehydrogenase family
ASC25_RS13660	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ASC25_RS13665	COG2151	metal-sulfur cluster biosynthetic enzyme
ASC25_RS13670	COG3396	Phenylacetate-CoA oxygenase
ASC25_RS13675	COG3460	Phenylacetate-CoA oxygenase
ASC25_RS13680	COG3396	Phenylacetate-CoA oxygenase
ASC25_RS13685	COG3327	negative regulation of DNA-templated transcription, initiation
ASC25_RS13695	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ASC25_RS13700	COG0501	Belongs to the peptidase M48B family
ASC25_RS13705	COG1162	GTPase activity
ASC25_RS13710	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASC25_RS13715	COG0601	transmembrane transport
ASC25_RS13720	COG0747	negative chemotaxis
ASC25_RS13765	COG0668	transmembrane transport
ASC25_RS13770	COG0165	Argininosuccinate lyase
ASC25_RS13790	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ASC25_RS13795	COG0303	'Molybdopterin
ASC25_RS13800	COG0521	Mo-molybdopterin cofactor biosynthetic process
ASC25_RS13815	COG0315	cyclic pyranopterin monophosphate synthase activity
ASC25_RS13825	COG0412	Dienelactone hydrolase
ASC25_RS13835	COG0678	peroxiredoxin activity
ASC25_RS13845	COG0697	spore germination
ASC25_RS13850	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ASC25_RS13875	COG0789	Transcriptional regulator
ASC25_RS13895	COG1028	Short-chain dehydrogenase reductase Sdr
ASC25_RS13905	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ASC25_RS13910	COG1845	cytochrome c oxidase, subunit III
ASC25_RS13915	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ASC25_RS13925	COG0477	Major facilitator Superfamily
ASC25_RS13955	COG3468	outer membrane autotransporter barrel domain protein
ASC25_RS13965	COG1309	transcriptional regulator
ASC25_RS13970	COG2271	Major facilitator Superfamily
ASC25_RS14005	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ASC25_RS14005	COG0506	proline dehydrogenase activity
ASC25_RS14005	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ASC25_RS14015	COG3008	intermembrane lipid transfer
ASC25_RS14015	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ASC25_RS14020	COG2995	paraquat-inducible protein a
ASC25_RS14025	COG0542	response to heat
ASC25_RS14030	COG4953	penicillin-binding protein 1C
ASC25_RS14040	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ASC25_RS14045	COG1278	Cold shock
ASC25_RS14055	COG0183	Belongs to the thiolase family
ASC25_RS14060	COG0038	chloride channel
ASC25_RS14065	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ASC25_RS14070	COG1570	exodeoxyribonuclease VII activity
ASC25_RS14080	COG0811	peptide transport
ASC25_RS14085	COG0848	biopolymer transport protein
ASC25_RS14090	COG1663	tetraacyldisaccharide 4'-kinase activity
ASC25_RS14095	COG2835	tetraacyldisaccharide 4'-kinase activity
ASC25_RS14100	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ASC25_RS14105	COG0563	adenylate kinase activity
ASC25_RS14115	COG0728	peptidoglycan biosynthetic process
ASC25_RS14125	COG0268	Binds directly to 16S ribosomal RNA
ASC25_RS14155	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ASC25_RS14180	COG0436	Aminotransferase
ASC25_RS14185	COG3737	Protein of unknown function (DUF498/DUF598)
ASC25_RS14190	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ASC25_RS14195	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ASC25_RS14200	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ASC25_RS14210	COG0305	Participates in initiation and elongation during chromosome replication
ASC25_RS14220	COG0359	binds to the 23S rRNA
ASC25_RS14225	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ASC25_RS14230	COG2965	DNA replication, synthesis of RNA primer
ASC25_RS14235	COG0360	Binds together with S18 to 16S ribosomal RNA
ASC25_RS14240	COG1469	GTP cyclohydrolase I activity
ASC25_RS14245	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ASC25_RS14250	COG0142	geranyltranstransferase activity
ASC25_RS14255	COG1722	exodeoxyribonuclease VII activity
ASC25_RS14265	COG3181	Tripartite tricarboxylate transporter family receptor
ASC25_RS14285	COG2239	Acts as a magnesium transporter
ASC25_RS14295	COG2855	membrane
ASC25_RS14305	COG1473	amidohydrolase
ASC25_RS14310	COG0318	PFAM AMP-dependent synthetase and ligase
ASC25_RS14335	COG1501	Belongs to the glycosyl hydrolase 31 family
ASC25_RS14340	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ASC25_RS14345	COG2011	ABC-type metal ion transport system permease component
ASC25_RS14365	COG1454	alcohol dehydrogenase
ASC25_RS14395	COG2186	Transcriptional regulator
ASC25_RS14400	COG3181	Tripartite tricarboxylate transporter family receptor
ASC25_RS14420	COG1175	transmembrane transport
ASC25_RS14425	COG0395	ABC-type sugar transport system, permease component
ASC25_RS14430	COG3842	ATPase activity
ASC25_RS14435	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ASC25_RS14445	COG1653	transport
ASC25_RS14465	COG2818	Glycosylase
ASC25_RS14470	COG2982	Protein involved in outer membrane biogenesis
ASC25_RS14480	COG1309	transcriptional regulator
ASC25_RS14485	COG1028	Short-chain dehydrogenase reductase Sdr
ASC25_RS14545	COG0583	DNA-binding transcription factor activity
ASC25_RS14550	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ASC25_RS14555	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ASC25_RS14570	COG1028	Short-chain dehydrogenase reductase Sdr
ASC25_RS14575	COG0477	Major facilitator Superfamily
ASC25_RS14585	COG0583	DNA-binding transcription factor activity
ASC25_RS14590	COG1448	Aminotransferase
ASC25_RS14595	COG1418	mRNA catabolic process
ASC25_RS14620	COG1063	alcohol dehydrogenase
ASC25_RS14640	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ASC25_RS14650	COG0318	PFAM AMP-dependent synthetase and ligase
ASC25_RS14660	COG1522	sequence-specific DNA binding
ASC25_RS14665	COG3181	Tripartite tricarboxylate transporter family receptor
ASC25_RS14670	COG0307	riboflavin synthase, alpha
ASC25_RS14675	COG0154	amidase activity
ASC25_RS14695	COG2807	transmembrane transport
ASC25_RS14700	COG0590	tRNA wobble adenosine to inosine editing
ASC25_RS14710	COG0583	DNA-binding transcription factor activity
ASC25_RS14725	COG1902	pentaerythritol trinitrate reductase activity
ASC25_RS14745	COG0559	Belongs to the binding-protein-dependent transport system permease family
ASC25_RS14750	COG0251	oxidation-reduction process
ASC25_RS14755	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ASC25_RS14765	COG1414	Transcriptional regulator
ASC25_RS14770	COG1028	Short-chain dehydrogenase reductase Sdr
ASC25_RS14785	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ASC25_RS14800	COG1024	Enoyl-CoA hydratase
ASC25_RS14805	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ASC25_RS14810	COG0154	amidase activity
ASC25_RS14850	COG3909	cytochrome
ASC25_RS14855	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ASC25_RS14860	COG0625	glutathione transferase activity
ASC25_RS14865	COG0730	response to heat
ASC25_RS14870	COG0482	sulfurtransferase activity
ASC25_RS14875	COG0583	DNA-binding transcription factor activity
ASC25_RS14895	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ASC25_RS14920	COG2819	hydrolase of the alpha beta superfamily
ASC25_RS14925	COG0247	lactate metabolic process
ASC25_RS14930	COG0277	FAD linked oxidase domain protein
ASC25_RS14935	COG0277	FAD linked oxidase domain protein
ASC25_RS14940	COG0277	FAD linked oxidase domain protein
ASC25_RS14945	COG3210	domain, Protein
ASC25_RS14945	COG3064	Membrane
ASC25_RS14945	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
ASC25_RS14945	COG3210	domain, Protein
ASC25_RS14945	COG3064	Membrane
ASC25_RS14945	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
ASC25_RS14950	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ASC25_RS14955	COG0312	modulator of DNA gyrase
ASC25_RS14990	COG1666	GTP binding
ASC25_RS15035	COG3220	belongs to the UPF0276 family
ASC25_RS15055	COG0640	Transcriptional regulator
ASC25_RS15060	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ASC25_RS15065	COG1845	cytochrome c oxidase, subunit III
ASC25_RS15070	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ASC25_RS15080	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
ASC25_RS15115	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ASC25_RS15120	COG0583	DNA-binding transcription factor activity
ASC25_RS15150	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ASC25_RS15150	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ASC25_RS15165	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ASC25_RS15170	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ASC25_RS15180	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ASC25_RS15195	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
ASC25_RS15200	COG0316	Belongs to the HesB IscA family
ASC25_RS15210	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ASC25_RS15215	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ASC25_RS15220	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ASC25_RS15225	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ASC25_RS15230	COG0312	modulator of DNA gyrase
ASC25_RS15235	COG3028	Belongs to the UPF0307 family
ASC25_RS15250	COG1116	anion transmembrane transporter activity
ASC25_RS15255	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ASC25_RS15260	COG1335	isochorismatase
ASC25_RS15265	COG0346	lactoylglutathione lyase activity
ASC25_RS15270	COG0513	Belongs to the DEAD box helicase family
ASC25_RS15275	COG3069	C4-dicarboxylate transmembrane transporter activity
ASC25_RS15280	COG1802	Transcriptional regulator
ASC25_RS15295	COG1042	CoA-binding domain protein
ASC25_RS15295	COG0045	succinate-CoA ligase (ADP-forming) activity
ASC25_RS15295	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ASC25_RS15300	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ASC25_RS15315	COG1522	sequence-specific DNA binding
ASC25_RS15350	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ASC25_RS15355	COG1696	Membrane protein involved in D-alanine export
ASC25_RS15380	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ASC25_RS15390	COG2264	protein methyltransferase activity
ASC25_RS15395	COG0439	Biotin carboxylase
ASC25_RS15400	COG0511	ligase activity, forming carbon-carbon bonds
ASC25_RS15405	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ASC25_RS15410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ASC25_RS15415	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ASC25_RS15420	COG3150	esterase
ASC25_RS15425	COG0557	exoribonuclease II activity
ASC25_RS15435	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ASC25_RS15455	COG1522	sequence-specific DNA binding
ASC25_RS15460	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ASC25_RS15465	COG1028	Short-chain dehydrogenase reductase Sdr
ASC25_RS15485	COG0653	protein targeting
ASC25_RS15490	COG0739	heme binding
ASC25_RS15500	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ASC25_RS15505	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ASC25_RS15515	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ASC25_RS15520	COG1181	Belongs to the D-alanine--D-alanine ligase family
ASC25_RS15525	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ASC25_RS15530	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ASC25_RS15540	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ASC25_RS15545	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ASC25_RS15550	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ASC25_RS15560	COG3116	cell division
ASC25_RS15565	COG0275	rRNA processing
ASC25_RS15570	COG2001	Belongs to the MraZ family
ASC25_RS15580	COG0488	(ABC) transporter
ASC25_RS15585	COG0418	dihydroorotase activity
ASC25_RS15590	COG1473	amidohydrolase
ASC25_RS15640	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ASC25_RS15645	COG4654	Cytochrome c, class I
ASC25_RS15650	COG0129	dihydroxy-acid dehydratase activity
ASC25_RS15655	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ASC25_RS15705	COG2084	Dehydrogenase
ASC25_RS15710	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ASC25_RS15725	COG2096	Adenosyltransferase
ASC25_RS15735	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ASC25_RS15740	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ASC25_RS15750	COG0523	cobalamin synthesis protein
ASC25_RS15755	COG0735	belongs to the Fur family
ASC25_RS15775	COG0803	Belongs to the bacterial solute-binding protein 9 family
ASC25_RS15785	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
ASC25_RS15795	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ASC25_RS15805	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ASC25_RS15810	COG1560	Kdo2-lipid A biosynthetic process
ASC25_RS15820	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ASC25_RS15835	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ASC25_RS15840	COG1950	PFAM Membrane protein of
ASC25_RS15855	COG0583	DNA-binding transcription factor activity
ASC25_RS15865	COG0477	Major facilitator Superfamily
ASC25_RS15880	COG0617	tRNA 3'-terminal CCA addition
ASC25_RS15890	COG0513	Belongs to the DEAD box helicase family
ASC25_RS15895	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ASC25_RS15910	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ASC25_RS15915	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
ASC25_RS15975	COG1280	lysine exporter protein (LysE YggA)
ASC25_RS15990	COG0405	Gamma-glutamyltransferase
ASC25_RS16000	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ASC25_RS16030	COG1309	transcriptional regulator
ASC25_RS16040	COG3181	Tripartite tricarboxylate transporter family receptor
ASC25_RS16050	COG0745	RESPONSE REGULATOR receiver
ASC25_RS16115	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ASC25_RS16140	COG0582	viral genome integration into host DNA
ASC25_RS16145	COG0012	GTP binding
ASC25_RS16155	COG0193	aminoacyl-tRNA hydrolase activity
ASC25_RS16160	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ASC25_RS16165	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ASC25_RS16175	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ASC25_RS16180	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
ASC25_RS16190	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ASC25_RS16215	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
ASC25_RS16225	COG1368	sulfuric ester hydrolase activity
ASC25_RS16230	COG0642	Histidine kinase
ASC25_RS16235	COG0745	RESPONSE REGULATOR receiver
ASC25_RS16240	COG0277	FAD linked oxidase domain protein
ASC25_RS16255	COG0166	Belongs to the GPI family
ASC25_RS16260	COG0438	transferase activity, transferring glycosyl groups
ASC25_RS16265	COG0438	transferase activity, transferring glycosyl groups
ASC25_RS16280	COG0438	transferase activity, transferring glycosyl groups
ASC25_RS16295	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ASC25_RS16300	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ASC25_RS16305	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
ASC25_RS16315	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ASC25_RS16325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ASC25_RS16330	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ASC25_RS16340	COG0747	negative chemotaxis
ASC25_RS16345	COG0601	transmembrane transport
ASC25_RS16350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASC25_RS16370	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ASC25_RS16375	COG0830	nickel cation binding
ASC25_RS16385	COG0804	urea catabolic process
ASC25_RS16390	COG0832	Belongs to the urease beta subunit family
ASC25_RS16400	COG0831	urea catabolic process
ASC25_RS16405	COG0829	nickel cation binding
ASC25_RS16415	COG0633	Ferredoxin
ASC25_RS16430	COG2188	Transcriptional regulator
ASC25_RS16455	COG2719	SpoVR family
ASC25_RS16460	COG2718	Belongs to the UPF0229 family
ASC25_RS16475	COG1028	Short-chain dehydrogenase reductase Sdr
ASC25_RS16480	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ASC25_RS16495	COG1960	acyl-CoA dehydrogenase activity
ASC25_RS16540	COG0183	Belongs to the thiolase family
ASC25_RS16545	COG2030	dehydratase
ASC25_RS16600	COG0328	RNA-DNA hybrid ribonuclease activity
ASC25_RS16605	COG2226	methyltransferase
ASC25_RS16610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ASC25_RS16615	COG0741	lytic transglycosylase activity
ASC25_RS16615	COG1388	LysM domain
ASC25_RS16635	COG2979	Protein of unknown function (DUF533)
ASC25_RS16670	COG1271	oxidase subunit
ASC25_RS16675	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ASC25_RS16680	COG0850	regulation of cytokinetic process
ASC25_RS16685	COG2894	cell division
ASC25_RS16690	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
ASC25_RS16710	COG0488	(ABC) transporter
ASC25_RS16725	COG0601	transmembrane transport
ASC25_RS16735	COG1215	transferase activity, transferring glycosyl groups
ASC25_RS16750	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ASC25_RS16760	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ASC25_RS16780	COG0318	PFAM AMP-dependent synthetase and ligase
ASC25_RS16785	COG2188	Transcriptional regulator
ASC25_RS16790	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ASC25_RS16795	COG2814	Major facilitator Superfamily
ASC25_RS16805	COG0259	pyridoxamine-phosphate oxidase activity
ASC25_RS16810	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ASC25_RS16825	COG0583	DNA-binding transcription factor activity
ASC25_RS16830	COG1960	acyl-CoA dehydrogenase activity
ASC25_RS16850	COG0134	indole-3-glycerol-phosphate synthase activity
ASC25_RS16855	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ASC25_RS16860	COG0512	Glutamine amidotransferase of anthranilate synthase
ASC25_RS16870	COG0546	phosphoglycolate phosphatase activity
ASC25_RS16875	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ASC25_RS16880	COG2967	ApaG domain
ASC25_RS16885	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ASC25_RS16890	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ASC25_RS16895	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ASC25_RS16900	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ASC25_RS16910	COG0037	tRNA processing
ASC25_RS16920	COG3634	alkyl hydroperoxide reductase activity
ASC25_RS16925	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ASC25_RS16930	COG1024	Enoyl-CoA hydratase
ASC25_RS16955	COG0356	it plays a direct role in the translocation of protons across the membrane
ASC25_RS16965	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ASC25_RS16970	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ASC25_RS16975	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ASC25_RS16980	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ASC25_RS16985	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ASC25_RS16990	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ASC25_RS17000	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ASC25_RS17005	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ASC25_RS17010	COG0210	DNA helicase
ASC25_RS17020	COG2195	Cleaves the N-terminal amino acid of tripeptides
ASC25_RS17030	COG4172	Belongs to the ABC transporter superfamily
ASC25_RS17035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASC25_RS17040	COG0601	transmembrane transport
ASC25_RS17060	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ASC25_RS17065	COG1024	Enoyl-CoA hydratase
ASC25_RS17070	COG1024	Enoyl-CoA hydratase
ASC25_RS17095	COG1250	3-hydroxyacyl-CoA dehydrogenase
ASC25_RS17125	COG2132	Multicopper oxidase
ASC25_RS17135	COG1250	3-hydroxyacyl-CoA dehydrogenase
ASC25_RS17135	COG1024	Enoyl-CoA hydratase
ASC25_RS17145	COG1414	Transcriptional regulator
ASC25_RS17155	COG0154	amidase activity
ASC25_RS17185	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ASC25_RS17190	COG3568	Endonuclease Exonuclease Phosphatase
ASC25_RS17195	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ASC25_RS17230	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ASC25_RS17240	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ASC25_RS17255	COG1137	ATPase activity
ASC25_RS17260	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ASC25_RS17270	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
ASC25_RS17275	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ASC25_RS17275	COG2010	Cytochrome c
ASC25_RS17285	COG1660	Displays ATPase and GTPase activities
ASC25_RS17290	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ASC25_RS17325	COG3181	Tripartite tricarboxylate transporter family receptor
ASC25_RS17335	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ASC25_RS17340	COG2890	protein-(glutamine-N5) methyltransferase activity
ASC25_RS17345	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ASC25_RS17350	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ASC25_RS17400	COG1960	acyl-CoA dehydrogenase activity
ASC25_RS17410	COG0183	Belongs to the thiolase family
ASC25_RS17415	COG1522	sequence-specific DNA binding
ASC25_RS17420	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ASC25_RS17440	COG1024	Enoyl-CoA hydratase
ASC25_RS17455	COG0604	alcohol dehydrogenase
ASC25_RS17475	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ASC25_RS17485	COG1960	acyl-CoA dehydrogenase activity
ASC25_RS17490	COG1960	acyl-CoA dehydrogenase activity
ASC25_RS17495	COG0277	FAD linked oxidase domain protein
ASC25_RS17505	COG3181	Tripartite tricarboxylate transporter family receptor
ASC25_RS17530	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ASC25_RS17540	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ASC25_RS17545	COG3181	Tripartite tricarboxylate transporter family receptor
ASC25_RS17550	COG1960	acyl-CoA dehydrogenase activity
ASC25_RS17570	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ASC25_RS17575	COG1024	Enoyl-CoA hydratase
ASC25_RS17580	COG1960	acyl-CoA dehydrogenase activity
ASC25_RS17600	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ASC25_RS17605	COG0022	dehydrogenase e1 component
ASC25_RS17610	COG1024	Enoyl-CoA hydratase
ASC25_RS17615	COG0508	dehydrogenase complex catalyzes the overall conversion of
ASC25_RS17635	COG0683	leucine binding
ASC25_RS17640	COG0559	Belongs to the binding-protein-dependent transport system permease family
ASC25_RS17645	COG0411	ABC transporter
ASC25_RS17655	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ASC25_RS17670	COG3181	Tripartite tricarboxylate transporter family receptor
ASC25_RS17700	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ASC25_RS17705	COG0793	Belongs to the peptidase S41A family
ASC25_RS17710	COG4942	peptidase
ASC25_RS17715	COG0588	phosphoglycerate mutase activity
ASC25_RS17720	COG1054	Belongs to the UPF0176 family
ASC25_RS17725	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ASC25_RS17730	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
ASC25_RS17735	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ASC25_RS17740	COG3181	Tripartite tricarboxylate transporter family receptor
ASC25_RS17755	COG2226	methyltransferase
ASC25_RS17760	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ASC25_RS17775	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ASC25_RS17780	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ASC25_RS17805	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ASC25_RS17830	COG1335	isochorismatase
ASC25_RS17835	COG2309	aminopeptidase activity
ASC25_RS17840	COG0596	Alpha beta hydrolase
ASC25_RS17845	COG3473	Maleate cis-trans isomerase
ASC25_RS17855	COG2068	MobA-Related Protein
ASC25_RS17880	COG2204	response regulator
ASC25_RS17885	COG5000	phosphorelay sensor kinase activity
ASC25_RS17895	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ASC25_RS17895	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ASC25_RS17905	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
ASC25_RS17935	COG0583	DNA-binding transcription factor activity
ASC25_RS17950	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ASC25_RS17955	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ASC25_RS17960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASC25_RS17975	COG0758	DNA mediated transformation
ASC25_RS17980	COG1522	sequence-specific DNA binding
ASC25_RS17990	COG0242	peptide deformylase activity
ASC25_RS18005	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ASC25_RS18015	COG0546	phosphoglycolate phosphatase activity
ASC25_RS18035	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ASC25_RS18040	COG1942	4-Oxalocrotonate Tautomerase
ASC25_RS18045	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ASC25_RS18070	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ASC25_RS18090	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ASC25_RS18095	COG1024	Enoyl-CoA hydratase
ASC25_RS18100	COG1414	Transcriptional regulator
ASC25_RS18105	COG0318	PFAM AMP-dependent synthetase and ligase
ASC25_RS18110	COG3181	Tripartite tricarboxylate transporter family receptor
ASC25_RS18140	COG0583	DNA-binding transcription factor activity
ASC25_RS18155	COG3422	double-strand break repair
ASC25_RS18160	COG0330	HflC and HflK could
ASC25_RS18170	COG0251	oxidation-reduction process
ASC25_RS18215	COG3723	Recombinational DNA repair protein, rece pathway
ASC25_RS18250	COG0582	viral genome integration into host DNA
ASC25_RS18275	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ASC25_RS18285	COG0706	membrane insertase activity
ASC25_RS18290	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ASC25_RS18295	COG0594	ribonuclease P activity
ASC25_RS18300	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ASC25_RS18305	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ASC25_RS18320	COG1414	Transcriptional regulator
ASC25_RS18325	COG0154	amidase activity
ASC25_RS18340	COG1304	FMN binding
ASC25_RS18360	COG1960	acyl-CoA dehydrogenase activity
ASC25_RS18380	COG1960	acyl-CoA dehydrogenase activity
ASC25_RS18395	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ASC25_RS18410	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ASC25_RS18415	COG3181	Tripartite tricarboxylate transporter family receptor
ASC25_RS18425	COG2358	TRAP transporter, solute receptor (TAXI family
ASC25_RS18435	COG1629	transport
ASC25_RS18440	COG2922	Belongs to the Smg family
ASC25_RS18465	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ASC25_RS18470	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ASC25_RS18475	COG1028	Short-chain dehydrogenase reductase Sdr
ASC25_RS18480	COG1012	belongs to the aldehyde dehydrogenase family
ASC25_RS18490	COG0028	Belongs to the TPP enzyme family
ASC25_RS18495	COG1522	sequence-specific DNA binding
ASC25_RS18500	COG3781	membrane
ASC25_RS18510	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ASC25_RS18530	COG4206	TonB-dependent receptor
ASC25_RS18535	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ASC25_RS18540	COG2022	thiamine diphosphate biosynthetic process
ASC25_RS18545	COG0351	phosphomethylpyrimidine kinase
ASC25_RS18550	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ASC25_RS18565	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ASC25_RS18575	COG0628	permease
ASC25_RS18585	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ASC25_RS18595	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ASC25_RS18600	COG0049	tRNA binding
ASC25_RS18605	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ASC25_RS18610	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ASC25_RS18615	COG0051	transcription antitermination factor activity, RNA binding
ASC25_RS18620	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ASC25_RS18625	COG0088	Forms part of the polypeptide exit tunnel
ASC25_RS18630	COG0089	rRNA binding
ASC25_RS18635	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ASC25_RS18640	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ASC25_RS18645	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ASC25_RS18650	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ASC25_RS18655	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ASC25_RS18660	COG0255	Belongs to the universal ribosomal protein uL29 family
ASC25_RS18665	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ASC25_RS18685	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ASC25_RS18690	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ASC25_RS18695	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ASC25_RS18700	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ASC25_RS18705	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ASC25_RS18710	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ASC25_RS18715	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ASC25_RS18720	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ASC25_RS18725	COG1841	ribosomal large subunit assembly
ASC25_RS18730	COG0200	Binds to the 23S rRNA
ASC25_RS18735	COG0201	protein transport
ASC25_RS18740	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ASC25_RS18745	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ASC25_RS18750	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ASC25_RS18755	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ASC25_RS18760	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ASC25_RS18765	COG0202	RNA polymerase activity
ASC25_RS18770	COG0203	ribosomal protein L17
ASC25_RS18775	COG0537	adenosine 5'-monophosphoramidase activity
ASC25_RS18780	COG1324	tolerance protein
ASC25_RS18785	COG4232	protein-disulfide reductase activity
ASC25_RS18800	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ASC25_RS18810	COG1333	cytochrome c biogenesis protein
ASC25_RS18815	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ASC25_RS18830	COG1965	Belongs to the frataxin family
ASC25_RS18840	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ASC25_RS18845	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ASC25_RS18850	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ASC25_RS18865	COG2814	Major facilitator Superfamily
ASC25_RS18870	COG0629	single-stranded DNA binding
ASC25_RS18910	COG0402	S-adenosylhomocysteine deaminase activity
ASC25_RS18920	COG0438	transferase activity, transferring glycosyl groups
ASC25_RS18940	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ASC25_RS18965	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ASC25_RS18970	COG2186	Transcriptional regulator
ASC25_RS18990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ASC25_RS18995	COG1956	GAF domain-containing protein
ASC25_RS19000	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ASC25_RS19015	COG1652	LysM domain
ASC25_RS19030	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ASC25_RS19045	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ASC25_RS19075	COG3181	Tripartite tricarboxylate transporter family receptor
ASC25_RS19090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ASC25_RS19105	COG1024	Enoyl-CoA hydratase
ASC25_RS19120	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ASC25_RS19125	COG1309	transcriptional regulator
ASC25_RS19130	COG2816	NAD+ diphosphatase activity
ASC25_RS19135	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ASC25_RS19220	COG2814	Major facilitator Superfamily
ASC25_RS19225	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ASC25_RS19245	COG1999	signal sequence binding
ASC25_RS19250	COG0109	protoheme IX farnesyltransferase activity
ASC25_RS19290	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ASC25_RS19310	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ASC25_RS19315	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ASC25_RS19325	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
ASC25_RS19330	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
ASC25_RS19340	COG0070	glutamate synthase
ASC25_RS19340	COG0067	glutamate synthase
ASC25_RS19340	COG0069	glutamate synthase activity
ASC25_RS19350	COG3047	cAMP biosynthetic process
ASC25_RS19360	COG1127	ABC transporter
ASC25_RS19365	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ASC25_RS19370	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ASC25_RS19375	COG2853	Lipoprotein
ASC25_RS19385	COG1131	(ABC) transporter
ASC25_RS19390	COG0842	Transport permease protein
ASC25_RS19400	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ASC25_RS19405	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ASC25_RS19410	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ASC25_RS19415	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ASC25_RS19420	COG0131	Imidazoleglycerol-phosphate dehydratase
ASC25_RS19425	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ASC25_RS19430	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ASC25_RS19435	COG0107	imidazoleglycerol-phosphate synthase activity
ASC25_RS19440	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ASC25_RS19445	COG0140	phosphoribosyl-ATP diphosphatase activity
ASC25_RS19450	COG0537	adenosine 5'-monophosphoramidase activity
ASC25_RS19455	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ASC25_RS19460	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ASC25_RS19475	COG3181	Tripartite tricarboxylate transporter family receptor
ASC25_RS19510	COG3702	type iv secretory pathway
ASC25_RS19515	COG3451	type IV secretory pathway VirB4
ASC25_RS19530	COG3736	Type IV secretory pathway, component VirB8
ASC25_RS19535	COG3504	Conjugal transfer protein
ASC25_RS19540	COG2948	multi-organism process
ASC25_RS19545	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
ASC25_RS19555	COG0697	spore germination
ASC25_RS19575	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ASC25_RS19580	COG0747	negative chemotaxis
ASC25_RS19585	COG0601	transmembrane transport
ASC25_RS19590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASC25_RS19595	COG0444	Belongs to the ABC transporter superfamily
ASC25_RS19605	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ASC25_RS19615	COG0494	nUDIX hydrolase
ASC25_RS19655	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
ASC25_RS19660	COG0237	dephospho-CoA kinase activity
ASC25_RS19665	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ASC25_RS19680	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ASC25_RS19685	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ASC25_RS19695	COG0477	Major facilitator Superfamily
ASC25_RS19700	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ASC25_RS19715	COG1126	abc transporter atp-binding protein
ASC25_RS19720	COG0765	amino acid transport
ASC25_RS19725	COG4597	amino acid ABC transporter
ASC25_RS19730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASC25_RS19735	COG2884	Cell division ATP-binding protein ftsE
ASC25_RS19740	COG2177	Part of the ABC transporter FtsEX involved in
ASC25_RS19745	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ASC25_RS19755	COG1194	a g-specific adenine glycosylase
ASC25_RS19765	COG2226	methyltransferase
ASC25_RS19775	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ASC25_RS19780	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ASC25_RS19795	COG1024	Enoyl-CoA hydratase
ASC25_RS19815	COG1024	Enoyl-CoA hydratase
ASC25_RS19820	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ASC25_RS19825	COG3181	Tripartite tricarboxylate transporter family receptor
ASC25_RS19835	COG0753	catalase activity
ASC25_RS19840	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ASC25_RS19845	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ASC25_RS19855	COG2175	clavaminate synthase activity
ASC25_RS19860	COG1473	amidohydrolase
ASC25_RS19865	COG4608	Belongs to the ABC transporter superfamily
ASC25_RS19870	COG0444	Belongs to the ABC transporter superfamily
ASC25_RS19885	COG0747	negative chemotaxis
ASC25_RS19890	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ASC25_RS19925	COG0436	Aminotransferase
ASC25_RS19930	COG1278	Cold shock