locus-tag	class	description
B2G54_RS00005	COG0445	tRNA wobble uridine modification
B2G54_RS00010	COG0357	Ribosomal RNA small subunit methyltransferase G
B2G54_RS00015	COG1192	Involved in chromosome partitioning
B2G54_RS00025	COG1475	DNA binding
B2G54_RS00030	COG0252	asparaginase activity
B2G54_RS00055	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
B2G54_RS00065	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
B2G54_RS00075	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
B2G54_RS00080	COG0081	regulation of translation
B2G54_RS00085	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
B2G54_RS00090	COG0222	ribosome binding
B2G54_RS00095	COG0085	RNA polymerase activity
B2G54_RS00100	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
B2G54_RS00140	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B2G54_RS00165	COG1024	Enoyl-CoA hydratase
B2G54_RS00185	COG0752	glycyl-tRNA synthetase alpha subunit
B2G54_RS00190	COG0751	glycine-tRNA ligase activity
B2G54_RS00195	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
B2G54_RS00200	COG0204	Acyl-transferase
B2G54_RS00215	COG0242	peptide deformylase activity
B2G54_RS00255	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
B2G54_RS00260	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B2G54_RS00265	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B2G54_RS00265	COG2813	Specifically methylates the guanine in position
B2G54_RS00280	COG2223	nitrite transmembrane transporter activity
B2G54_RS00290	COG1794	racemase activity, acting on amino acids and derivatives
B2G54_RS00295	COG1126	abc transporter atp-binding protein
B2G54_RS00300	COG0765	amino acid transport
B2G54_RS00305	COG0765	amino acid transport
B2G54_RS00310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B2G54_RS00375	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B2G54_RS00405	COG0326	Molecular chaperone. Has ATPase activity
B2G54_RS00410	COG0625	glutathione transferase activity
B2G54_RS00425	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B2G54_RS00430	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
B2G54_RS00460	COG0438	transferase activity, transferring glycosyl groups
B2G54_RS00465	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
B2G54_RS00470	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
B2G54_RS00500	COG0859	PFAM glycosyl transferase family 9
B2G54_RS00515	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
B2G54_RS00525	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
B2G54_RS00530	COG1127	ABC transporter
B2G54_RS00550	COG1686	Belongs to the peptidase S11 family
B2G54_RS00560	COG2921	Belongs to the UPF0250 family
B2G54_RS00565	COG0321	lipoyl(octanoyl) transferase activity
B2G54_RS00570	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
B2G54_RS00605	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
B2G54_RS00615	COG0018	arginyl-trna synthetase
B2G54_RS00635	COG0395	ABC-type sugar transport system, permease component
B2G54_RS00640	COG1175	transmembrane transport
B2G54_RS00645	COG1653	transport
B2G54_RS00650	COG3842	ATPase activity
B2G54_RS00655	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
B2G54_RS00670	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
B2G54_RS00690	COG1609	Transcriptional regulator
B2G54_RS00700	COG0154	amidase activity
B2G54_RS00705	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B2G54_RS00715	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
B2G54_RS00725	COG0583	DNA-binding transcription factor activity
B2G54_RS00740	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
B2G54_RS00745	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B2G54_RS00760	COG1802	Transcriptional regulator
B2G54_RS00775	COG1024	Enoyl-CoA hydratase
B2G54_RS00790	COG3181	Tripartite tricarboxylate transporter family receptor
B2G54_RS00805	COG1984	allophanate hydrolase subunit 2
B2G54_RS00810	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
B2G54_RS00820	COG0583	DNA-binding transcription factor activity
B2G54_RS00825	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B2G54_RS00835	COG5002	protein histidine kinase activity
B2G54_RS00845	COG5002	protein histidine kinase activity
B2G54_RS00850	COG0745	RESPONSE REGULATOR receiver
B2G54_RS00855	COG2226	methyltransferase
B2G54_RS00870	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
B2G54_RS00890	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
B2G54_RS00900	COG0513	Belongs to the DEAD box helicase family
B2G54_RS00905	COG1280	lysine exporter protein (LysE YggA)
B2G54_RS00910	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
B2G54_RS00945	COG1054	Belongs to the UPF0176 family
B2G54_RS00950	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B2G54_RS00950	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B2G54_RS00960	COG0489	protein tyrosine kinase activity
B2G54_RS00975	COG0717	Belongs to the dCTP deaminase family
B2G54_RS01005	COG2081	HI0933 family
B2G54_RS01015	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
B2G54_RS01025	COG0404	The glycine cleavage system catalyzes the degradation of glycine
B2G54_RS01030	COG0509	glycine decarboxylation via glycine cleavage system
B2G54_RS01035	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B2G54_RS01035	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B2G54_RS01075	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B2G54_RS01080	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
B2G54_RS01085	COG1012	belongs to the aldehyde dehydrogenase family
B2G54_RS01110	COG4257	antibiotic catabolic process
B2G54_RS01120	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
B2G54_RS01125	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
B2G54_RS01135	COG1250	3-hydroxyacyl-CoA dehydrogenase
B2G54_RS01140	COG2031	fatty acid transporter
B2G54_RS01145	COG1028	Short-chain dehydrogenase reductase Sdr
B2G54_RS01150	COG1414	Transcriptional regulator
B2G54_RS01160	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
B2G54_RS01175	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B2G54_RS01195	COG1028	Short-chain dehydrogenase reductase Sdr
B2G54_RS01205	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B2G54_RS01215	COG2188	Transcriptional regulator
B2G54_RS01220	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
B2G54_RS01245	COG0617	tRNA 3'-terminal CCA addition
B2G54_RS01260	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
B2G54_RS01265	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
B2G54_RS01270	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
B2G54_RS01275	COG0586	Pfam SNARE associated Golgi protein
B2G54_RS01280	COG0860	N-Acetylmuramoyl-L-alanine amidase
B2G54_RS01285	COG0802	atpase or kinase
B2G54_RS01290	COG0114	fumarate hydratase activity
B2G54_RS01300	COG3181	Tripartite tricarboxylate transporter family receptor
B2G54_RS01310	COG0405	Gamma-glutamyltransferase
B2G54_RS01315	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B2G54_RS01325	COG1960	acyl-CoA dehydrogenase activity
B2G54_RS01350	COG1294	oxidase, subunit
B2G54_RS01360	COG4988	ABC transporter
B2G54_RS01365	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
B2G54_RS01370	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
B2G54_RS01385	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
B2G54_RS01415	COG2969	positive regulation of protein catabolic process
B2G54_RS01420	COG0625	glutathione transferase activity
B2G54_RS01425	COG2857	Cytochrome c1
B2G54_RS01430	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
B2G54_RS01435	COG0723	plastoquinol--plastocyanin reductase activity
B2G54_RS01440	COG1970	mechanosensitive ion channel activity
B2G54_RS01445	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
B2G54_RS01460	COG2808	Putative FMN-binding domain
B2G54_RS01465	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B2G54_RS01470	COG0747	negative chemotaxis
B2G54_RS01475	COG0657	acetylesterase activity
B2G54_RS01485	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B2G54_RS01490	COG2207	Transcriptional regulator
B2G54_RS01495	COG0129	dihydroxy-acid dehydratase activity
B2G54_RS01500	COG2814	Major facilitator Superfamily
B2G54_RS01505	COG0583	DNA-binding transcription factor activity
B2G54_RS01515	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
B2G54_RS01585	COG1024	Enoyl-CoA hydratase
B2G54_RS01590	COG1960	acyl-CoA dehydrogenase activity
B2G54_RS01615	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
B2G54_RS01620	COG0352	thiamine-phosphate diphosphorylase activity
B2G54_RS01635	COG1678	Uncharacterized ACR, COG1678
B2G54_RS01640	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
B2G54_RS01645	COG0540	Belongs to the ATCase OTCase family
B2G54_RS01660	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
B2G54_RS01670	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B2G54_RS01705	COG1234	tRNA 3'-trailer cleavage
B2G54_RS01715	COG0583	DNA-binding transcription factor activity
B2G54_RS01725	COG3064	Membrane
B2G54_RS01755	COG1683	Conserved Protein
B2G54_RS01760	COG1120	ATPase activity
B2G54_RS01765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B2G54_RS01770	COG4558	Periplasmic binding protein
B2G54_RS01775	COG3720	iron ion transport
B2G54_RS01785	COG3712	iron ion homeostasis
B2G54_RS01790	COG1595	DNA-templated transcription, initiation
B2G54_RS01825	COG1802	Transcriptional regulator
B2G54_RS01835	COG3069	C4-dicarboxylate transmembrane transporter activity
B2G54_RS01845	COG1012	belongs to the aldehyde dehydrogenase family
B2G54_RS01880	COG2860	membrane
B2G54_RS01885	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
B2G54_RS01890	COG0708	Exodeoxyribonuclease III
B2G54_RS01895	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
B2G54_RS01900	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
B2G54_RS01905	COG0154	amidase activity
B2G54_RS01910	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
B2G54_RS01915	COG1077	Cell shape determining protein MreB Mrl
B2G54_RS01920	COG1792	Involved in formation and maintenance of cell shape
B2G54_RS01930	COG0768	penicillin binding
B2G54_RS01935	COG0772	Belongs to the SEDS family
B2G54_RS01940	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
B2G54_RS01945	COG0471	metal ion transport
B2G54_RS01950	COG1309	transcriptional regulator
B2G54_RS01960	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
B2G54_RS01975	COG2823	Periplasmic or secreted lipoprotein
B2G54_RS01980	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
B2G54_RS01995	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B2G54_RS02005	COG0697	spore germination
B2G54_RS02035	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
B2G54_RS02040	COG0463	Glycosyl transferase, family 2
B2G54_RS02060	COG0786	glutamate:sodium symporter activity
B2G54_RS02070	COG2031	fatty acid transporter
B2G54_RS02085	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B2G54_RS02090	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B2G54_RS02100	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
B2G54_RS02115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B2G54_RS02125	COG1285	pathogenesis
B2G54_RS02130	COG1253	flavin adenine dinucleotide binding
B2G54_RS02135	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B2G54_RS02140	COG1024	Enoyl-CoA hydratase
B2G54_RS02145	COG3181	Tripartite tricarboxylate transporter family receptor
B2G54_RS02150	COG0583	DNA-binding transcription factor activity
B2G54_RS02155	COG1960	acyl-CoA dehydrogenase activity
B2G54_RS02165	COG0183	Belongs to the thiolase family
B2G54_RS02180	COG0583	DNA-binding transcription factor activity
B2G54_RS02185	COG1278	Cold shock
B2G54_RS02195	COG1802	Transcriptional regulator
B2G54_RS02200	COG1012	belongs to the aldehyde dehydrogenase family
B2G54_RS02205	COG2031	fatty acid transporter
B2G54_RS02210	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B2G54_RS02210	COG1017	nitric oxide dioxygenase activity
B2G54_RS02215	COG0251	oxidation-reduction process
B2G54_RS02235	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B2G54_RS02245	COG0583	DNA-binding transcription factor activity
B2G54_RS02250	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B2G54_RS02265	COG1960	acyl-CoA dehydrogenase activity
B2G54_RS02285	COG1960	acyl-CoA dehydrogenase activity
B2G54_RS02300	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B2G54_RS02315	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B2G54_RS02320	COG3181	Tripartite tricarboxylate transporter family receptor
B2G54_RS02330	COG2358	TRAP transporter, solute receptor (TAXI family
B2G54_RS02340	COG1629	transport
B2G54_RS02345	COG2922	Belongs to the Smg family
B2G54_RS02370	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
B2G54_RS02375	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B2G54_RS02380	COG1028	Short-chain dehydrogenase reductase Sdr
B2G54_RS02385	COG1012	belongs to the aldehyde dehydrogenase family
B2G54_RS02395	COG0028	Belongs to the TPP enzyme family
B2G54_RS02400	COG1522	sequence-specific DNA binding
B2G54_RS02405	COG3781	membrane
B2G54_RS02415	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
B2G54_RS02435	COG1530	ribonuclease E activity
B2G54_RS02445	COG0546	phosphoglycolate phosphatase activity
B2G54_RS02450	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
B2G54_RS02455	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
B2G54_RS02475	COG1304	FMN binding
B2G54_RS02490	COG0154	amidase activity
B2G54_RS02495	COG1414	Transcriptional regulator
B2G54_RS02510	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
B2G54_RS02515	COG0230	Belongs to the bacterial ribosomal protein bL34 family
B2G54_RS02520	COG0594	ribonuclease P activity
B2G54_RS02525	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
B2G54_RS02530	COG0706	membrane insertase activity
B2G54_RS02540	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
B2G54_RS02565	COG0582	viral genome integration into host DNA
B2G54_RS02600	COG3723	Recombinational DNA repair protein, rece pathway
B2G54_RS02645	COG0251	oxidation-reduction process
B2G54_RS02655	COG0330	HflC and HflK could
B2G54_RS02660	COG3422	double-strand break repair
B2G54_RS02675	COG0583	DNA-binding transcription factor activity
B2G54_RS02705	COG3181	Tripartite tricarboxylate transporter family receptor
B2G54_RS02710	COG0318	PFAM AMP-dependent synthetase and ligase
B2G54_RS02715	COG1414	Transcriptional regulator
B2G54_RS02720	COG1024	Enoyl-CoA hydratase
B2G54_RS02725	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B2G54_RS02745	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B2G54_RS02765	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B2G54_RS02770	COG1942	4-Oxalocrotonate Tautomerase
B2G54_RS02775	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
B2G54_RS02795	COG0546	phosphoglycolate phosphatase activity
B2G54_RS02805	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
B2G54_RS02810	COG0242	peptide deformylase activity
B2G54_RS02820	COG1522	sequence-specific DNA binding
B2G54_RS02825	COG0758	DNA mediated transformation
B2G54_RS02840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B2G54_RS02845	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B2G54_RS02850	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
B2G54_RS02865	COG0583	DNA-binding transcription factor activity
B2G54_RS02890	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
B2G54_RS02900	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B2G54_RS02900	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
B2G54_RS02910	COG5000	phosphorelay sensor kinase activity
B2G54_RS02915	COG2204	response regulator
B2G54_RS02940	COG2068	MobA-Related Protein
B2G54_RS02950	COG3473	Maleate cis-trans isomerase
B2G54_RS02955	COG0596	Alpha beta hydrolase
B2G54_RS02960	COG2309	aminopeptidase activity
B2G54_RS02965	COG1335	isochorismatase
B2G54_RS02990	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
B2G54_RS03015	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
B2G54_RS03020	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B2G54_RS03035	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
B2G54_RS03040	COG2226	methyltransferase
B2G54_RS03055	COG3181	Tripartite tricarboxylate transporter family receptor
B2G54_RS03060	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
B2G54_RS03065	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
B2G54_RS03070	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
B2G54_RS03075	COG1054	Belongs to the UPF0176 family
B2G54_RS03080	COG0588	phosphoglycerate mutase activity
B2G54_RS03085	COG4942	peptidase
B2G54_RS03090	COG0793	Belongs to the peptidase S41A family
B2G54_RS03095	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
B2G54_RS03125	COG3181	Tripartite tricarboxylate transporter family receptor
B2G54_RS03140	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B2G54_RS03150	COG0411	ABC transporter
B2G54_RS03155	COG0559	Belongs to the binding-protein-dependent transport system permease family
B2G54_RS03160	COG0683	leucine binding
B2G54_RS03180	COG0508	dehydrogenase complex catalyzes the overall conversion of
B2G54_RS03185	COG1024	Enoyl-CoA hydratase
B2G54_RS03190	COG0022	dehydrogenase e1 component
B2G54_RS03195	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
B2G54_RS03215	COG1960	acyl-CoA dehydrogenase activity
B2G54_RS03220	COG1024	Enoyl-CoA hydratase
B2G54_RS03225	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B2G54_RS03245	COG1960	acyl-CoA dehydrogenase activity
B2G54_RS03250	COG3181	Tripartite tricarboxylate transporter family receptor
B2G54_RS03255	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B2G54_RS03265	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B2G54_RS03285	COG3181	Tripartite tricarboxylate transporter family receptor
B2G54_RS03290	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B2G54_RS03320	COG3181	Tripartite tricarboxylate transporter family receptor
B2G54_RS03330	COG0277	FAD linked oxidase domain protein
B2G54_RS03335	COG1960	acyl-CoA dehydrogenase activity
B2G54_RS03340	COG1960	acyl-CoA dehydrogenase activity
B2G54_RS03350	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B2G54_RS03365	COG2072	flavoprotein involved in K transport
B2G54_RS03370	COG0604	alcohol dehydrogenase
B2G54_RS03385	COG1024	Enoyl-CoA hydratase
B2G54_RS03405	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B2G54_RS03410	COG1522	sequence-specific DNA binding
B2G54_RS03415	COG0183	Belongs to the thiolase family
B2G54_RS03425	COG1960	acyl-CoA dehydrogenase activity
B2G54_RS03475	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
B2G54_RS03480	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
B2G54_RS03485	COG2890	protein-(glutamine-N5) methyltransferase activity
B2G54_RS03490	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
B2G54_RS03500	COG3181	Tripartite tricarboxylate transporter family receptor
B2G54_RS03535	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
B2G54_RS03540	COG1660	Displays ATPase and GTPase activities
B2G54_RS03550	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B2G54_RS03550	COG2010	Cytochrome c
B2G54_RS03555	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
B2G54_RS03565	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
B2G54_RS03570	COG1137	ATPase activity
B2G54_RS03585	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
B2G54_RS03595	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
B2G54_RS03630	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
B2G54_RS03635	COG3568	Endonuclease Exonuclease Phosphatase
B2G54_RS03640	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B2G54_RS03675	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B2G54_RS03680	COG0154	amidase activity
B2G54_RS03690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B2G54_RS03695	COG0601	transmembrane transport
B2G54_RS03700	COG0747	negative chemotaxis
B2G54_RS03720	COG0019	diaminopimelate decarboxylase activity
B2G54_RS03735	COG2353	YceI-like domain
B2G54_RS03740	COG4774	siderophore transport
B2G54_RS03745	COG3712	iron ion homeostasis
B2G54_RS03785	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
B2G54_RS03790	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
B2G54_RS03795	COG0211	Belongs to the bacterial ribosomal protein bL27 family
B2G54_RS03800	COG0261	This protein binds to 23S rRNA in the presence of protein L20
B2G54_RS03810	COG0142	geranyltranstransferase activity
B2G54_RS03820	COG0583	DNA-binding transcription factor activity
B2G54_RS03830	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
B2G54_RS03835	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B2G54_RS03850	COG2994	toxin metabolic process
B2G54_RS03860	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
B2G54_RS03865	COG2274	protein secretion by the type I secretion system
B2G54_RS03870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B2G54_RS03875	COG1538	Outer membrane efflux protein
B2G54_RS03890	COG0765	amino acid transport
B2G54_RS03895	COG0765	amino acid transport
B2G54_RS03900	COG1126	abc transporter atp-binding protein
B2G54_RS03920	COG1028	Short-chain dehydrogenase reductase Sdr
B2G54_RS03930	COG1802	Transcriptional regulator
B2G54_RS03940	COG1802	Transcriptional regulator
B2G54_RS03950	COG0318	PFAM AMP-dependent synthetase and ligase
B2G54_RS03960	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B2G54_RS03980	COG0028	Belongs to the TPP enzyme family
B2G54_RS04000	COG0028	Belongs to the TPP enzyme family
B2G54_RS04005	COG0440	acetolactate synthase activity
B2G54_RS04010	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
B2G54_RS04015	COG1183	phosphatidylcholine synthase activity
B2G54_RS04030	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
B2G54_RS04035	COG1185	polyribonucleotide nucleotidyltransferase activity
B2G54_RS04050	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B2G54_RS04070	COG0149	triose-phosphate isomerase activity
B2G54_RS04075	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
B2G54_RS04085	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
B2G54_RS04095	COG3799	methylaspartate ammonia-lyase activity
B2G54_RS04130	COG0583	DNA-binding transcription factor activity
B2G54_RS04135	COG0626	cystathionine gamma-synthase activity
B2G54_RS04140	COG3608	succinylglutamate desuccinylase aspartoacylase
B2G54_RS04160	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B2G54_RS04180	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
B2G54_RS04195	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B2G54_RS04200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B2G54_RS04205	COG1733	regulation of RNA biosynthetic process
B2G54_RS04215	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
B2G54_RS04220	COG0583	DNA-binding transcription factor activity
B2G54_RS04225	COG1597	lipid kinase activity
B2G54_RS04235	COG0671	phosphoesterase, PA-phosphatase related
B2G54_RS04265	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
B2G54_RS04270	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B2G54_RS04275	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B2G54_RS04280	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B2G54_RS04285	COG0649	NAD binding
B2G54_RS04290	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
B2G54_RS04300	COG1034	ATP synthesis coupled electron transport
B2G54_RS04305	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
B2G54_RS04310	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B2G54_RS04320	COG0713	ATP synthesis coupled electron transport
B2G54_RS04335	COG1007	ATP synthesis coupled electron transport
B2G54_RS04345	COG4774	siderophore transport
B2G54_RS04350	COG4774	siderophore transport
B2G54_RS04365	COG0028	Belongs to the TPP enzyme family
B2G54_RS04370	COG3181	Tripartite tricarboxylate transporter family receptor
B2G54_RS04375	COG0583	DNA-binding transcription factor activity
B2G54_RS04380	COG0560	Phosphoserine phosphatase
B2G54_RS04385	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
B2G54_RS04390	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
B2G54_RS04395	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
B2G54_RS04405	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
B2G54_RS04410	COG0308	aminopeptidase N
B2G54_RS04425	COG5265	(ABC) transporter
B2G54_RS04430	COG0500	methyltransferase
B2G54_RS04450	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
B2G54_RS04480	COG0511	ligase activity, forming carbon-carbon bonds
B2G54_RS04505	COG2188	Transcriptional regulator
B2G54_RS04510	COG0439	Biotin carboxylase
B2G54_RS04515	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B2G54_RS04560	COG5265	(ABC) transporter
B2G54_RS04570	COG0667	Aldo Keto reductase
B2G54_RS04585	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
B2G54_RS04625	COG0583	DNA-binding transcription factor activity
B2G54_RS04640	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B2G54_RS04650	COG2079	MmgE PrpD family protein
B2G54_RS04655	COG1012	belongs to the aldehyde dehydrogenase family
B2G54_RS04660	COG1053	succinate dehydrogenase
B2G54_RS04685	COG0179	Fumarylacetoacetate (FAA) hydrolase
B2G54_RS04700	COG0583	DNA-binding transcription factor activity
B2G54_RS04740	COG0583	DNA-binding transcription factor activity
B2G54_RS04765	COG2814	Major facilitator Superfamily
B2G54_RS04775	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
B2G54_RS04790	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
B2G54_RS04800	COG0287	Prephenate dehydrogenase
B2G54_RS04805	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
B2G54_RS04810	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
B2G54_RS04830	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
B2G54_RS04835	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
B2G54_RS04840	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B2G54_RS04845	COG1555	photosystem II stabilization
B2G54_RS04845	COG1596	polysaccharide export
B2G54_RS04860	COG2951	lytic endotransglycosylase activity
B2G54_RS04865	COG0123	including yeast histone deacetylase and acetoin utilization protein
B2G54_RS04880	COG1960	acyl-CoA dehydrogenase activity
B2G54_RS04885	COG0450	alkyl hydroperoxide reductase
B2G54_RS04900	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
B2G54_RS04905	COG4208	sulfate ABC transporter
B2G54_RS04910	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
B2G54_RS04940	COG0335	large ribosomal subunit rRNA binding
B2G54_RS04950	COG0667	Aldo Keto reductase
B2G54_RS04960	COG2814	Major facilitator Superfamily
B2G54_RS04965	COG3161	chorismate lyase activity
B2G54_RS04970	COG1187	pseudouridine synthase activity
B2G54_RS04980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B2G54_RS05005	COG1999	signal sequence binding
B2G54_RS05010	COG0339	signal peptide processing
B2G54_RS05015	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
B2G54_RS05020	COG4566	intracellular signal transduction
B2G54_RS05030	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
B2G54_RS05035	COG0508	dehydrogenase complex catalyzes the overall conversion of
B2G54_RS05040	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B2G54_RS05045	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
B2G54_RS05055	COG1385	rRNA (uridine-N3-)-methyltransferase activity
B2G54_RS05060	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
B2G54_RS05065	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
B2G54_RS05070	COG0126	phosphoglycerate kinase activity
B2G54_RS05075	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
B2G54_RS05080	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
B2G54_RS05095	COG0625	glutathione transferase activity
B2G54_RS05130	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
B2G54_RS05135	COG0306	phosphate transporter
B2G54_RS05140	COG0521	Mo-molybdopterin cofactor biosynthetic process
B2G54_RS05150	COG0739	heme binding
B2G54_RS05160	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
B2G54_RS05195	COG0745	RESPONSE REGULATOR receiver
B2G54_RS05210	COG0840	transmembrane signaling receptor activity
B2G54_RS05220	COG2201	protein-glutamate methylesterase activity
B2G54_RS05225	COG0745	RESPONSE REGULATOR receiver
B2G54_RS05230	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
B2G54_RS05255	COG0667	Aldo Keto reductase
B2G54_RS05265	COG4535	Mg2 and Co2 transporter CorC
B2G54_RS05270	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
B2G54_RS05275	COG1702	phosphate starvation-inducible protein PhoH
B2G54_RS05280	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
B2G54_RS05295	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B2G54_RS05300	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B2G54_RS05305	COG1862	Preprotein translocase
B2G54_RS05315	COG0343	queuine tRNA-ribosyltransferase activity
B2G54_RS05320	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
B2G54_RS05325	COG2027	D-alanyl-D-alanine carboxypeptidase
B2G54_RS05330	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
B2G54_RS05340	COG3468	outer membrane autotransporter barrel domain protein
B2G54_RS05345	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
B2G54_RS05345	COG1648	precorrin-2 dehydrogenase activity
B2G54_RS05370	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
B2G54_RS05375	COG0741	lytic transglycosylase activity
B2G54_RS05380	COG0436	Aminotransferase
B2G54_RS05400	COG2732	(Barnase) inhibitor
B2G54_RS05415	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
B2G54_RS05440	COG0248	Ppx GppA phosphatase
B2G54_RS05450	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B2G54_RS05460	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B2G54_RS05465	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
B2G54_RS05470	COG1534	Rna-binding protein
B2G54_RS05505	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
B2G54_RS05520	COG1295	ribonuclease BN
B2G54_RS05530	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
B2G54_RS05535	COG0745	RESPONSE REGULATOR receiver
B2G54_RS05540	COG2205	protein histidine kinase activity
B2G54_RS05575	COG1022	Amp-dependent synthetase and ligase
B2G54_RS05590	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
B2G54_RS05595	COG1028	Short-chain dehydrogenase reductase Sdr
B2G54_RS05605	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
B2G54_RS05620	COG1136	(ABC) transporter
B2G54_RS05625	COG0084	hydrolase, TatD family'
B2G54_RS05655	COG2333	competence protein COMEC
B2G54_RS05655	COG0658	competence protein
B2G54_RS05665	COG0613	PHP domain protein
B2G54_RS05685	COG3539	Fimbrial protein
B2G54_RS05690	COG0280	phosphate acetyltransferase
B2G54_RS05690	COG0281	malic enzyme
B2G54_RS05700	COG1522	sequence-specific DNA binding
B2G54_RS05710	COG0567	Dehydrogenase, E1 component
B2G54_RS05715	COG0508	dehydrogenase complex catalyzes the overall conversion of
B2G54_RS05720	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B2G54_RS05725	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
B2G54_RS05730	COG1028	Short-chain dehydrogenase reductase Sdr
B2G54_RS05735	COG0583	DNA-binding transcription factor activity
B2G54_RS05745	COG3181	Tripartite tricarboxylate transporter family receptor
B2G54_RS05770	COG1595	DNA-templated transcription, initiation
B2G54_RS05775	COG3712	iron ion homeostasis
B2G54_RS05780	COG4774	siderophore transport
B2G54_RS05805	COG0180	Tryptophanyl-tRNA synthetase
B2G54_RS05810	COG2183	response to ionizing radiation
B2G54_RS05815	COG1199	ATP-dependent helicase activity
B2G54_RS05825	COG0564	pseudouridine synthase activity
B2G54_RS05835	COG3243	poly(R)-hydroxyalkanoic acid synthase
B2G54_RS05840	COG1028	Short-chain dehydrogenase reductase Sdr
B2G54_RS05845	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
B2G54_RS05860	COG0672	)-iron permease
B2G54_RS05900	COG0583	DNA-binding transcription factor activity
B2G54_RS05910	COG2814	Major facilitator Superfamily
B2G54_RS05925	COG1619	proteins homologs of microcin C7 resistance protein MccF
B2G54_RS05940	COG2084	Dehydrogenase
B2G54_RS05945	COG3181	Tripartite tricarboxylate transporter family receptor
B2G54_RS05970	COG2988	succinylglutamate desuccinylase activity
B2G54_RS05995	COG0765	amino acid transport
B2G54_RS06000	COG0765	amino acid transport
B2G54_RS06005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B2G54_RS06040	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B2G54_RS06045	COG1595	DNA-templated transcription, initiation
B2G54_RS06055	COG3530	Putative quorum-sensing-regulated virulence factor
B2G54_RS06060	COG0494	nUDIX hydrolase
B2G54_RS06075	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B2G54_RS06080	COG0542	response to heat
B2G54_RS06095	COG3468	outer membrane autotransporter barrel domain protein
B2G54_RS06100	COG3468	outer membrane autotransporter barrel domain protein
B2G54_RS06110	COG5441	Belongs to the UPF0261 family
B2G54_RS06115	COG5564	TIM-barrel signal transduction protein
B2G54_RS06130	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
B2G54_RS06145	COG1477	protein flavinylation
B2G54_RS06165	COG1131	(ABC) transporter
B2G54_RS06170	COG0842	Transport permease protein
B2G54_RS06180	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
B2G54_RS06185	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
B2G54_RS06185	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
B2G54_RS06190	COG1562	ergosterol biosynthetic process
B2G54_RS06195	COG1562	ergosterol biosynthetic process
B2G54_RS06200	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
B2G54_RS06205	COG1028	Short-chain dehydrogenase reductase Sdr
B2G54_RS06225	COG2304	oxidoreductase activity
B2G54_RS06245	COG0534	Mate efflux family protein
B2G54_RS06255	COG0254	rRNA binding
B2G54_RS06260	COG3483	tryptophan 2,3-dioxygenase activity
B2G54_RS06265	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
B2G54_RS06270	COG2003	Belongs to the UPF0758 family
B2G54_RS06275	COG1047	Peptidyl-prolyl cis-trans
B2G54_RS06280	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
B2G54_RS06285	COG0625	glutathione transferase activity
B2G54_RS06305	COG0523	cobalamin synthesis protein
B2G54_RS06315	COG0583	DNA-binding transcription factor activity
B2G54_RS06325	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
B2G54_RS06330	COG1187	pseudouridine synthase activity
B2G54_RS06335	COG0779	Required for maturation of 30S ribosomal subunits
B2G54_RS06340	COG0195	Participates in both transcription termination and antitermination
B2G54_RS06340	COG2251	uridine kinase activity
B2G54_RS06345	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
B2G54_RS06350	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
B2G54_RS06355	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
B2G54_RS06375	COG1611	Belongs to the LOG family
B2G54_RS06390	COG0412	Dienelactone hydrolase
B2G54_RS06395	COG1283	sodium-dependent phosphate transmembrane transporter activity
B2G54_RS06400	COG1760	l-serine dehydratase
B2G54_RS06405	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
B2G54_RS06410	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
B2G54_RS06420	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
B2G54_RS06445	COG2311	Membrane
B2G54_RS06455	COG0697	spore germination
B2G54_RS06470	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
B2G54_RS06490	COG0559	Belongs to the binding-protein-dependent transport system permease family
B2G54_RS06505	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
B2G54_RS06515	COG1653	transport
B2G54_RS06520	COG1175	transmembrane transport
B2G54_RS06525	COG0395	ABC-type sugar transport system, permease component
B2G54_RS06530	COG3842	ATPase activity
B2G54_RS06565	COG2363	Small membrane protein
B2G54_RS06580	COG1464	Belongs to the NlpA lipoprotein family
B2G54_RS06590	COG0688	phosphatidylethanolamine metabolic process
B2G54_RS06605	COG0095	Lipoate-protein ligase
B2G54_RS06620	COG0625	glutathione transferase activity
B2G54_RS06625	COG0386	Belongs to the glutathione peroxidase family
B2G54_RS06645	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B2G54_RS06675	COG2259	Doxx family
B2G54_RS06690	COG0667	Aldo Keto reductase
B2G54_RS06720	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
B2G54_RS06740	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
B2G54_RS06750	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
B2G54_RS06785	COG0392	lysyltransferase activity
B2G54_RS06800	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B2G54_RS06805	COG3568	Endonuclease Exonuclease Phosphatase
B2G54_RS06815	COG1695	Transcriptional regulator
B2G54_RS06835	COG0583	DNA-binding transcription factor activity
B2G54_RS06850	COG1802	Transcriptional regulator
B2G54_RS06860	COG3181	Tripartite tricarboxylate transporter family receptor
B2G54_RS06870	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B2G54_RS06885	COG0066	3-isopropylmalate dehydratase activity
B2G54_RS06895	COG3181	Tripartite tricarboxylate transporter family receptor
B2G54_RS06900	COG4948	Mandelate Racemase Muconate Lactonizing
B2G54_RS06915	COG1126	abc transporter atp-binding protein
B2G54_RS06920	COG0765	amino acid transport
B2G54_RS06925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B2G54_RS06945	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
B2G54_RS06970	COG1815	bacterial-type flagellum-dependent cell motility
B2G54_RS06975	COG1558	bacterial-type flagellum-dependent cell motility
B2G54_RS06985	COG1749	Flagellar hook protein flgE
B2G54_RS07000	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
B2G54_RS07005	COG1706	bacterial-type flagellum-dependent cell motility
B2G54_RS07015	COG1256	bacterial-type flagellum assembly
B2G54_RS07025	COG0840	transmembrane signaling receptor activity
B2G54_RS07030	COG0840	transmembrane signaling receptor activity
B2G54_RS07035	COG0840	transmembrane signaling receptor activity
B2G54_RS07055	COG1338	Plays a role in the flagellum-specific transport system
B2G54_RS07075	COG1580	Controls the rotational direction of flagella during chemotaxis
B2G54_RS07100	COG1157	protein secretion by the type III secretion system
B2G54_RS07110	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B2G54_RS07120	COG1677	Flagellar hook-basal body complex protein FliE
B2G54_RS07130	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
B2G54_RS07165	COG0285	dihydrofolate synthase activity
B2G54_RS07195	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
B2G54_RS07200	COG0024	Methionine aminopeptidase
B2G54_RS07205	COG0052	Belongs to the universal ribosomal protein uS2 family
B2G54_RS07210	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
B2G54_RS07215	COG0528	UMP kinase activity
B2G54_RS07220	COG0233	cytoplasmic translational termination
B2G54_RS07225	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
B2G54_RS07235	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
B2G54_RS07240	COG0750	zinc metalloprotease
B2G54_RS07245	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B2G54_RS07250	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
B2G54_RS07255	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B2G54_RS07260	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
B2G54_RS07270	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B2G54_RS07275	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
B2G54_RS07280	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B2G54_RS07285	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
B2G54_RS07295	COG0518	GMP synthase (glutamine-hydrolyzing) activity
B2G54_RS07295	COG0519	Catalyzes the synthesis of GMP from XMP
B2G54_RS07310	COG0330	HflC and HflK could
B2G54_RS07315	COG3706	GGDEF domain
B2G54_RS07320	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
B2G54_RS07325	COG2867	negative regulation of translational initiation
B2G54_RS07335	COG1960	acyl-CoA dehydrogenase activity
B2G54_RS07340	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
B2G54_RS07370	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
B2G54_RS07375	COG0505	Belongs to the CarA family
B2G54_RS07380	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
B2G54_RS07390	COG0406	alpha-ribazole phosphatase activity
B2G54_RS07400	COG3842	ATPase activity
B2G54_RS07420	COG5001	Diguanylate cyclase
B2G54_RS07425	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
B2G54_RS07435	COG1763	Mo-molybdopterin cofactor biosynthetic process
B2G54_RS07440	COG0303	'Molybdopterin
B2G54_RS07445	COG0746	molybdenum cofactor guanylyltransferase activity
B2G54_RS07450	COG0489	protein tyrosine kinase activity
B2G54_RS07480	COG0243	molybdopterin cofactor binding
B2G54_RS07480	COG3383	formate dehydrogenase (NAD+) activity
B2G54_RS07485	COG0437	4 iron, 4 sulfur cluster binding
B2G54_RS07515	COG1122	ATPase activity
B2G54_RS07525	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
B2G54_RS07530	COG0066	3-isopropylmalate dehydratase activity
B2G54_RS07535	COG0473	3-isopropylmalate dehydrogenase activity
B2G54_RS07540	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
B2G54_RS07550	COG0101	tRNA pseudouridine synthase activity
B2G54_RS07555	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
B2G54_RS07570	COG0135	phosphoribosylanthranilate isomerase activity
B2G54_RS07595	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B2G54_RS07605	COG2197	response regulator
B2G54_RS07610	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
B2G54_RS07615	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
B2G54_RS07620	COG0189	ligase activity
B2G54_RS07630	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B2G54_RS07635	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B2G54_RS07645	COG1764	response to oxidative stress
B2G54_RS07650	COG2423	ornithine cyclodeaminase activity
B2G54_RS07660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B2G54_RS07665	COG0765	amino acid transport
B2G54_RS07670	COG0765	amino acid transport
B2G54_RS07675	COG1126	abc transporter atp-binding protein
B2G54_RS07730	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
B2G54_RS07740	COG2944	sequence-specific DNA binding
B2G54_RS07750	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
B2G54_RS07755	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
B2G54_RS07760	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
B2G54_RS07765	COG0009	L-threonylcarbamoyladenylate synthase
B2G54_RS07770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B2G54_RS07775	COG1414	Transcriptional regulator
B2G54_RS07790	COG0765	amino acid transport
B2G54_RS07795	COG1126	abc transporter atp-binding protein
B2G54_RS07800	COG0028	Belongs to the TPP enzyme family
B2G54_RS07815	COG0028	Belongs to the TPP enzyme family
B2G54_RS07820	COG0583	DNA-binding transcription factor activity
B2G54_RS07825	COG4974	Belongs to the 'phage' integrase family
B2G54_RS07830	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
B2G54_RS07835	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
B2G54_RS07850	COG1686	Belongs to the peptidase S11 family
B2G54_RS07860	COG2814	Major facilitator Superfamily
B2G54_RS07870	COG1074	ATP-dependent DNA helicase activity
B2G54_RS07885	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
B2G54_RS07890	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
B2G54_RS07895	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
B2G54_RS07915	COG2321	neutral zinc metallopeptidase
B2G54_RS07920	COG0009	L-threonylcarbamoyladenylate synthase
B2G54_RS07965	COG3360	Dodecin
B2G54_RS07970	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
B2G54_RS07975	COG2850	peptidyl-arginine hydroxylation
B2G54_RS07980	COG3539	Fimbrial protein
B2G54_RS07985	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
B2G54_RS07990	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B2G54_RS08010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B2G54_RS08015	COG0765	amino acid transport
B2G54_RS08020	COG1126	abc transporter atp-binding protein
B2G54_RS08025	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B2G54_RS08030	COG1758	RNA polymerase activity
B2G54_RS08035	COG0194	GDP metabolic process
B2G54_RS08040	COG3258	Cytochrome c
B2G54_RS08045	COG2863	cytochrome
B2G54_RS08050	COG1028	Short-chain dehydrogenase reductase Sdr
B2G54_RS08055	COG0791	NLP P60 protein
B2G54_RS08060	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
B2G54_RS08080	COG1561	YicC-like family, N-terminal region
B2G54_RS08085	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
B2G54_RS08100	COG0840	transmembrane signaling receptor activity
B2G54_RS08105	COG2200	EAL domain
B2G54_RS08105	COG2199	diguanylate cyclase activity
B2G54_RS08110	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
B2G54_RS08120	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B2G54_RS08125	COG0174	glutamine synthetase
B2G54_RS08135	COG2204	response regulator
B2G54_RS08140	COG0583	DNA-binding transcription factor activity
B2G54_RS08145	COG1741	Belongs to the pirin family
B2G54_RS08150	COG1741	Belongs to the pirin family
B2G54_RS08160	COG3842	ATPase activity
B2G54_RS08165	COG1178	ABC-type Fe3 transport system permease component
B2G54_RS08170	COG1840	ABC-type Fe3 transport system, periplasmic component
B2G54_RS08180	COG0583	DNA-binding transcription factor activity
B2G54_RS08190	COG0656	L-ascorbic acid biosynthetic process
B2G54_RS08205	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
B2G54_RS08210	COG0583	DNA-binding transcription factor activity
B2G54_RS08225	COG0783	Belongs to the Dps family
B2G54_RS08245	COG0463	Glycosyl transferase, family 2
B2G54_RS08265	COG0438	transferase activity, transferring glycosyl groups
B2G54_RS08280	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
B2G54_RS08310	COG3119	arylsulfatase activity
B2G54_RS08345	COG0714	Associated with various cellular activities
B2G54_RS08365	COG1028	Short-chain dehydrogenase reductase Sdr
B2G54_RS08370	COG0861	Integral membrane protein TerC family
B2G54_RS08415	COG0300	oxidoreductase activity
B2G54_RS08435	COG2197	response regulator
B2G54_RS08445	COG2944	sequence-specific DNA binding
B2G54_RS08450	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
B2G54_RS08455	COG0625	glutathione transferase activity
B2G54_RS08485	COG0179	Fumarylacetoacetate (FAA) hydrolase
B2G54_RS08490	COG1028	Short-chain dehydrogenase reductase Sdr
B2G54_RS08535	COG0431	NADPH-dependent FMN reductase
B2G54_RS08565	COG1028	Short-chain dehydrogenase reductase Sdr
B2G54_RS08570	COG0583	DNA-binding transcription factor activity
B2G54_RS08585	COG3181	Tripartite tricarboxylate transporter family receptor
B2G54_RS08590	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
B2G54_RS08590	COG2111	Na H antiporter
B2G54_RS08595	COG1006	Multisubunit Na H antiporter MnhC subunit
B2G54_RS08600	COG0651	ATP synthesis coupled electron transport
B2G54_RS08605	COG1863	multisubunit Na H antiporter MnhE subunit
B2G54_RS08610	COG2212	antiporter activity
B2G54_RS08635	COG0590	tRNA wobble adenosine to inosine editing
B2G54_RS08640	COG1619	proteins homologs of microcin C7 resistance protein MccF
B2G54_RS08645	COG1024	Enoyl-CoA hydratase
B2G54_RS08660	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
B2G54_RS08665	COG0488	(ABC) transporter
B2G54_RS08700	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B2G54_RS08710	COG2252	PERMEase
B2G54_RS08715	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
B2G54_RS08725	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
B2G54_RS08730	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
B2G54_RS08760	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
B2G54_RS08765	COG0789	Transcriptional regulator
B2G54_RS08775	COG0678	peroxiredoxin activity
B2G54_RS08775	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
B2G54_RS08785	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
B2G54_RS08790	COG0584	glycerophosphoryl diester phosphodiesterase
B2G54_RS08795	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B2G54_RS08805	COG4181	ATPase activity
B2G54_RS08815	COG2823	Periplasmic or secreted lipoprotein
B2G54_RS08825	COG3237	CsbD-like
B2G54_RS08830	COG1181	Belongs to the D-alanine--D-alanine ligase family
B2G54_RS08830	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
B2G54_RS08835	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
B2G54_RS08835	COG0189	ligase activity
B2G54_RS08855	COG2833	Protein of unknown function (DUF455)
B2G54_RS08860	COG2951	lytic endotransglycosylase activity
B2G54_RS08880	COG1522	sequence-specific DNA binding
B2G54_RS08890	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
B2G54_RS08895	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
B2G54_RS08900	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
B2G54_RS08905	COG0196	riboflavin kinase activity
B2G54_RS08910	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
B2G54_RS08935	COG0210	DNA helicase
B2G54_RS08940	COG4771	TonB-dependent receptor
B2G54_RS08945	COG0488	(ABC) transporter
B2G54_RS08950	COG2890	protein-(glutamine-N5) methyltransferase activity
B2G54_RS08955	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B2G54_RS08960	COG2171	N-acyltransferase activity
B2G54_RS08995	COG1278	Cold shock
B2G54_RS09015	COG0544	peptidyl-prolyl cis-trans isomerase activity
B2G54_RS09020	COG0740	serine-type endopeptidase activity
B2G54_RS09025	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
B2G54_RS09030	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
B2G54_RS09035	COG0583	DNA-binding transcription factor activity
B2G54_RS09040	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B2G54_RS09055	COG1024	Enoyl-CoA hydratase
B2G54_RS09065	COG0183	Belongs to the thiolase family
B2G54_RS09070	COG1028	Short-chain dehydrogenase reductase Sdr
B2G54_RS09075	COG1960	acyl-CoA dehydrogenase activity
B2G54_RS09090	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
B2G54_RS09115	COG3468	outer membrane autotransporter barrel domain protein
B2G54_RS09120	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
B2G54_RS09130	COG0556	nucleotide-excision repair
B2G54_RS09135	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B2G54_RS09145	COG1104	cysteine desulfurase activity
B2G54_RS09150	COG0822	iron-sulfur transferase activity
B2G54_RS09155	COG0316	Belongs to the HesB IscA family
B2G54_RS09160	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
B2G54_RS09165	COG0443	Heat shock 70 kDa protein
B2G54_RS09170	COG0633	Ferredoxin
B2G54_RS09190	COG1024	Enoyl-CoA hydratase
B2G54_RS09210	COG3395	kinase activity
B2G54_RS09215	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
B2G54_RS09230	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
B2G54_RS09240	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B2G54_RS09265	COG0747	negative chemotaxis
B2G54_RS09270	COG0601	transmembrane transport
B2G54_RS09275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B2G54_RS09280	COG4172	Belongs to the ABC transporter superfamily
B2G54_RS09285	COG0154	amidase activity
B2G54_RS09330	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
B2G54_RS09335	COG0425	Belongs to the sulfur carrier protein TusA family
B2G54_RS09345	COG0228	four-way junction DNA binding
B2G54_RS09350	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
B2G54_RS09355	COG0336	Belongs to the RNA methyltransferase TrmD family
B2G54_RS09360	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B2G54_RS09390	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
B2G54_RS09395	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
B2G54_RS09400	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
B2G54_RS09405	COG0084	hydrolase, TatD family'
B2G54_RS09420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B2G54_RS09430	COG1126	abc transporter atp-binding protein
B2G54_RS09435	COG0010	Belongs to the arginase family
B2G54_RS09440	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
B2G54_RS09445	COG1012	belongs to the aldehyde dehydrogenase family
B2G54_RS09455	COG0028	Belongs to the TPP enzyme family
B2G54_RS09465	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
B2G54_RS09465	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
B2G54_RS09475	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B2G54_RS09490	COG3189	MarR family transcriptional regulator
B2G54_RS09495	COG2010	Cytochrome c
B2G54_RS09520	COG4336	lyase activity
B2G54_RS09530	COG2205	protein histidine kinase activity
B2G54_RS09530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B2G54_RS09535	COG2197	response regulator
B2G54_RS09540	COG3064	Membrane
B2G54_RS09540	COG3210	domain, Protein
B2G54_RS09540	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
B2G54_RS09550	COG3121	Chaperone
B2G54_RS09555	COG3188	usher protein
B2G54_RS09560	COG3539	Fimbrial protein
B2G54_RS09565	COG2831	hemolysin activation secretion protein
B2G54_RS09580	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B2G54_RS09605	COG0583	DNA-binding transcription factor activity
B2G54_RS09630	COG0668	transmembrane transport
B2G54_RS09650	COG0483	inositol monophosphate 1-phosphatase activity
B2G54_RS09655	COG1253	flavin adenine dinucleotide binding
B2G54_RS09660	COG1968	undecaprenyl-diphosphatase activity
B2G54_RS09665	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B2G54_RS09680	COG0215	cysteine-tRNA ligase activity
B2G54_RS09690	COG0825	malonyl-CoA metabolic process
B2G54_RS09700	COG0037	tRNA processing
B2G54_RS09705	COG0527	aspartate kinase activity
B2G54_RS09730	COG1250	3-hydroxyacyl-CoA dehydrogenase
B2G54_RS09735	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
B2G54_RS09735	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
B2G54_RS09750	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B2G54_RS09755	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
B2G54_RS09760	COG1028	Short-chain dehydrogenase reductase Sdr
B2G54_RS09770	COG0583	DNA-binding transcription factor activity
B2G54_RS09795	COG3842	ATPase activity
B2G54_RS09805	COG0446	pyridine nucleotide-disulphide oxidoreductase
B2G54_RS09805	COG1902	pentaerythritol trinitrate reductase activity
B2G54_RS09810	COG1414	Transcriptional regulator
B2G54_RS09815	COG1832	CoA-binding protein
B2G54_RS09825	COG0251	oxidation-reduction process
B2G54_RS09850	COG1902	pentaerythritol trinitrate reductase activity
B2G54_RS09860	COG1215	transferase activity, transferring glycosyl groups
B2G54_RS09865	COG1649	PFAM Uncharacterised BCR, COG1649
B2G54_RS09865	COG0726	polysaccharide deacetylase
B2G54_RS09885	COG1846	Transcriptional regulator
B2G54_RS09915	COG2010	Cytochrome c
B2G54_RS09915	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B2G54_RS09920	COG2080	2 iron, 2 sulfur cluster binding
B2G54_RS09925	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B2G54_RS09930	COG3473	Maleate cis-trans isomerase
B2G54_RS09935	COG0596	Alpha beta hydrolase
B2G54_RS09940	COG2309	aminopeptidase activity
B2G54_RS09945	COG1335	isochorismatase
B2G54_RS09960	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B2G54_RS09960	COG1017	nitric oxide dioxygenase activity
B2G54_RS09975	COG3181	Tripartite tricarboxylate transporter family receptor
B2G54_RS09985	COG2197	response regulator
B2G54_RS10000	COG0166	Belongs to the GPI family
B2G54_RS10005	COG1045	serine acetyltransferase
B2G54_RS10015	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
B2G54_RS10020	COG0483	inositol monophosphate 1-phosphatase activity
B2G54_RS10025	COG1012	belongs to the aldehyde dehydrogenase family
B2G54_RS10030	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
B2G54_RS10045	COG0210	DNA helicase
B2G54_RS10050	COG0598	Magnesium transport protein CorA
B2G54_RS10060	COG0747	negative chemotaxis
B2G54_RS10065	COG0601	transmembrane transport
B2G54_RS10070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B2G54_RS10075	COG4172	Belongs to the ABC transporter superfamily
B2G54_RS10080	COG1846	Transcriptional regulator
B2G54_RS10125	COG4964	Belongs to the GSP D family
B2G54_RS10165	COG2204	response regulator
B2G54_RS10180	COG1595	DNA-templated transcription, initiation
B2G54_RS10190	COG3474	cytochrome
B2G54_RS10195	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
B2G54_RS10210	COG3384	dioxygenase
B2G54_RS10215	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
B2G54_RS10240	COG2885	chlorophyll binding
B2G54_RS10275	COG0697	spore germination
B2G54_RS10280	COG0730	response to heat
B2G54_RS10300	COG0583	DNA-binding transcription factor activity
B2G54_RS10305	COG0427	acetyl-CoA hydrolase
B2G54_RS10360	COG1250	3-hydroxyacyl-CoA dehydrogenase
B2G54_RS10365	COG0154	amidase activity
B2G54_RS10375	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
B2G54_RS10390	COG0495	leucyl-tRNA aminoacylation
B2G54_RS10395	COG2814	Major facilitator Superfamily
B2G54_RS10420	COG0267	Belongs to the bacterial ribosomal protein bL33 family
B2G54_RS10425	COG0227	Belongs to the bacterial ribosomal protein bL28 family
B2G54_RS10430	COG2814	Major facilitator Superfamily
B2G54_RS10435	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
B2G54_RS10450	COG4176	ABC-type proline glycine betaine transport system permease component
B2G54_RS10460	COG1942	4-Oxalocrotonate Tautomerase
B2G54_RS10465	COG0183	Belongs to the thiolase family
B2G54_RS10475	COG1802	Transcriptional regulator
B2G54_RS10485	COG1024	Enoyl-CoA hydratase
B2G54_RS10490	COG0318	PFAM AMP-dependent synthetase and ligase
B2G54_RS10495	COG0318	PFAM AMP-dependent synthetase and ligase
B2G54_RS10505	COG2032	superoxide dismutase activity
B2G54_RS10520	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
B2G54_RS10545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B2G54_RS10550	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B2G54_RS10560	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
B2G54_RS10565	COG0736	holo-[acyl-carrier-protein] synthase activity
B2G54_RS10570	COG1472	Belongs to the glycosyl hydrolase 3 family
B2G54_RS10575	COG0322	excinuclease ABC activity
B2G54_RS10580	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
B2G54_RS10595	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
B2G54_RS10595	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
B2G54_RS10600	COG2224	Isocitrate lyase
B2G54_RS10620	COG0559	Belongs to the binding-protein-dependent transport system permease family
B2G54_RS10630	COG4638	Rieske (2fe-2S)
B2G54_RS10640	COG1024	Enoyl-CoA hydratase
B2G54_RS10650	COG0633	Ferredoxin
B2G54_RS10655	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B2G54_RS10670	COG0183	Belongs to the thiolase family
B2G54_RS10715	COG2346	COG2346, Truncated hemoglobins
B2G54_RS10840	COG2207	Transcriptional regulator
B2G54_RS10895	COG1132	(ABC) transporter
B2G54_RS10920	COG0659	secondary active sulfate transmembrane transporter activity
B2G54_RS10950	COG2169	Transcriptional regulator
B2G54_RS10955	COG5507	3-demethylubiquinone-9 3-methyltransferase
B2G54_RS10960	COG0384	phenazine biosynthesis protein PhzF
B2G54_RS10965	COG0583	DNA-binding transcription factor activity
B2G54_RS10970	COG2733	membrane
B2G54_RS10985	COG1012	belongs to the aldehyde dehydrogenase family
B2G54_RS10990	COG3284	Transcriptional regulator
B2G54_RS11005	COG1380	Effector of murein hydrolase LrgA
B2G54_RS11010	COG4106	trans-aconitate 2-methyltransferase activity
B2G54_RS11010	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
B2G54_RS11020	COG0156	8-amino-7-oxononanoate synthase activity
B2G54_RS11090	COG1131	(ABC) transporter
B2G54_RS11095	COG0842	Transport permease protein
B2G54_RS11100	COG0628	permease
B2G54_RS11130	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B2G54_RS11140	COG0828	Belongs to the bacterial ribosomal protein bS21 family
B2G54_RS11145	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
B2G54_RS11150	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
B2G54_RS11155	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
B2G54_RS11160	COG0330	HflC and HflK could
B2G54_RS11165	COG0330	HflC and HflK could
B2G54_RS11170	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
B2G54_RS11175	COG1923	regulation of RNA biosynthetic process
B2G54_RS11180	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
B2G54_RS11185	COG1160	GTP binding
B2G54_RS11190	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B2G54_RS11195	COG2976	Protein conserved in bacteria
B2G54_RS11200	COG0124	histidyl-tRNA synthetase
B2G54_RS11205	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
B2G54_RS11215	COG0820	rRNA (adenine-C2-)-methyltransferase activity
B2G54_RS11220	COG0105	UTP biosynthetic process
B2G54_RS11225	COG0525	valine-tRNA ligase activity
B2G54_RS11240	COG0642	Histidine kinase
B2G54_RS11255	COG0587	DNA-directed DNA polymerase activity
B2G54_RS11265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B2G54_RS11270	COG1959	2 iron, 2 sulfur cluster binding
B2G54_RS11275	COG1017	nitric oxide dioxygenase activity
B2G54_RS11275	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B2G54_RS11305	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B2G54_RS11310	COG2358	TRAP transporter, solute receptor (TAXI family
B2G54_RS11340	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B2G54_RS11345	COG1366	Belongs to the anti-sigma-factor antagonist family
B2G54_RS11350	COG2172	sigma factor antagonist activity
B2G54_RS11355	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
B2G54_RS11365	COG2208	phosphoserine phosphatase activity
B2G54_RS11365	COG2770	Histidine kinase
B2G54_RS11390	COG1595	DNA-templated transcription, initiation
B2G54_RS11405	COG4792	protein secretion
B2G54_RS11410	COG4791	protein targeting
B2G54_RS11415	COG4794	Type iii secretion
B2G54_RS11420	COG4790	Type iii secretion
B2G54_RS11455	COG4669	(LipO)protein
B2G54_RS11520	COG4789	Type iii secretion
B2G54_RS11550	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B2G54_RS11555	COG0840	transmembrane signaling receptor activity
B2G54_RS11560	COG2233	PERMEase
B2G54_RS11580	COG0492	ferredoxin-NADP+ reductase activity
B2G54_RS11585	COG1840	ABC-type Fe3 transport system, periplasmic component
B2G54_RS11590	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B2G54_RS11595	COG1178	ABC-type Fe3 transport system permease component
B2G54_RS11600	COG3842	ATPase activity
B2G54_RS11605	COG0583	DNA-binding transcription factor activity
B2G54_RS11625	COG0501	Belongs to the peptidase M48B family
B2G54_RS11635	COG0697	spore germination
B2G54_RS11645	COG1846	Transcriptional regulator
B2G54_RS11655	COG1566	PFAM secretion protein HlyD family protein
B2G54_RS11660	COG2814	Major facilitator Superfamily
B2G54_RS11665	COG0473	3-isopropylmalate dehydrogenase activity
B2G54_RS11675	COG0747	negative chemotaxis
B2G54_RS11685	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B2G54_RS11700	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
B2G54_RS11725	COG1012	belongs to the aldehyde dehydrogenase family
B2G54_RS11735	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B2G54_RS11740	COG1115	amino acid carrier protein
B2G54_RS11745	COG0433	COG0433 Predicted ATPase
B2G54_RS11750	COG0217	transcriptional regulatory protein
B2G54_RS11755	COG0151	Belongs to the GarS family
B2G54_RS11760	COG0408	coproporphyrinogen oxidase activity
B2G54_RS11765	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
B2G54_RS11770	COG0799	negative regulation of ribosome biogenesis
B2G54_RS11775	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
B2G54_RS11780	COG0424	maF-like protein
B2G54_RS11785	COG3468	outer membrane autotransporter barrel domain protein
B2G54_RS11825	COG1530	ribonuclease E activity
B2G54_RS11830	COG0077	Prephenate dehydratase
B2G54_RS11845	COG1132	(ABC) transporter
B2G54_RS11850	COG0859	PFAM glycosyl transferase family 9
B2G54_RS11875	COG2194	sulfuric ester hydrolase activity
B2G54_RS11880	COG0438	transferase activity, transferring glycosyl groups
B2G54_RS11885	COG0463	Glycosyl transferase, family 2
B2G54_RS11890	COG0726	polysaccharide deacetylase
B2G54_RS11895	COG0438	transferase activity, transferring glycosyl groups
B2G54_RS11910	COG1643	Atp-dependent helicase
B2G54_RS11915	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
B2G54_RS11915	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
B2G54_RS11920	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
B2G54_RS11930	COG0704	Plays a role in the regulation of phosphate uptake
B2G54_RS11935	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
B2G54_RS11940	COG1960	acyl-CoA dehydrogenase activity
B2G54_RS11965	COG1177	transmembrane transport
B2G54_RS11970	COG1176	ABC-type spermidine putrescine transport system, permease component I
B2G54_RS11975	COG3842	ATPase activity
B2G54_RS11980	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
B2G54_RS11995	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
B2G54_RS12000	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B2G54_RS12010	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
B2G54_RS12010	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
B2G54_RS12030	COG0372	Belongs to the citrate synthase family
B2G54_RS12035	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
B2G54_RS12040	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
B2G54_RS12045	COG1053	succinate dehydrogenase
B2G54_RS12050	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
B2G54_RS12055	COG2009	succinate dehydrogenase
B2G54_RS12060	COG2188	Transcriptional regulator
B2G54_RS12065	COG0039	L-malate dehydrogenase activity
B2G54_RS12095	COG1981	membrane
B2G54_RS12120	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B2G54_RS12130	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
B2G54_RS12160	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
B2G54_RS12165	COG0148	phosphopyruvate hydratase activity
B2G54_RS12175	COG2877	3-deoxy-8-phosphooctulonate synthase activity
B2G54_RS12180	COG0504	CTP synthase activity
B2G54_RS12205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B2G54_RS12215	COG0747	negative chemotaxis
B2G54_RS12220	COG4172	Belongs to the ABC transporter superfamily
B2G54_RS12225	COG1446	asparaginase
B2G54_RS12255	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
B2G54_RS12270	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
B2G54_RS12275	COG0697	spore germination
B2G54_RS12280	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B2G54_RS12290	COG3193	protein, possibly involved in utilization of glycolate and propanediol
B2G54_RS12295	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B2G54_RS12300	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B2G54_RS12305	COG0791	NLP P60 protein
B2G54_RS12320	COG0583	DNA-binding transcription factor activity
B2G54_RS12335	COG0583	DNA-binding transcription factor activity
B2G54_RS12345	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
B2G54_RS12360	COG0670	Belongs to the BI1 family
B2G54_RS12365	COG3181	Tripartite tricarboxylate transporter family receptor
B2G54_RS12375	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B2G54_RS12385	COG1381	Involved in DNA repair and RecF pathway recombination
B2G54_RS12390	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
B2G54_RS12395	COG0571	ribonuclease III activity
B2G54_RS12400	COG0681	Belongs to the peptidase S26 family
B2G54_RS12405	COG0481	GTPase activity
B2G54_RS12410	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B2G54_RS12435	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B2G54_RS12440	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B2G54_RS12455	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B2G54_RS12460	COG0416	fatty acid biosynthetic process
B2G54_RS12465	COG0333	Belongs to the bacterial ribosomal protein bL32 family
B2G54_RS12470	COG1399	metal-binding, possibly nucleic acid-binding protein
B2G54_RS12475	COG0424	maF-like protein
B2G54_RS12485	COG3023	N-Acetylmuramoyl-L-alanine amidase
B2G54_RS12490	COG1289	transmembrane transporter activity
B2G54_RS12500	COG3022	response to hydroperoxide
B2G54_RS12510	COG1028	Short-chain dehydrogenase reductase Sdr
B2G54_RS12525	COG3486	L-lysine 6-monooxygenase (NADPH) activity
B2G54_RS12555	COG2814	Major facilitator Superfamily
B2G54_RS12575	COG3706	GGDEF domain
B2G54_RS12600	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
B2G54_RS12605	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
B2G54_RS12610	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
B2G54_RS12615	COG1674	ftsk spoiiie
B2G54_RS12620	COG0492	ferredoxin-NADP+ reductase activity
B2G54_RS12625	COG1193	negative regulation of DNA recombination
B2G54_RS12640	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B2G54_RS12655	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
B2G54_RS12660	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
B2G54_RS12665	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
B2G54_RS12675	COG0745	RESPONSE REGULATOR receiver
B2G54_RS12720	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B2G54_RS12740	COG0612	Peptidase, M16
B2G54_RS12745	COG0484	heat shock protein binding
B2G54_RS12750	COG0443	Heat shock 70 kDa protein
B2G54_RS12760	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
B2G54_RS12770	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
B2G54_RS12775	COG1420	regulation of RNA biosynthetic process
B2G54_RS12780	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
B2G54_RS12785	COG0497	DNA recombination
B2G54_RS12790	COG0735	belongs to the Fur family
B2G54_RS12795	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B2G54_RS12800	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
B2G54_RS12805	COG0812	UDP-N-acetylmuramate dehydrogenase activity
B2G54_RS12840	COG0404	The glycine cleavage system catalyzes the degradation of glycine
B2G54_RS12840	COG0446	pyridine nucleotide-disulphide oxidoreductase
B2G54_RS12845	COG4311	Sarcosine oxidase, delta subunit
B2G54_RS12850	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B2G54_RS12860	COG0583	DNA-binding transcription factor activity
B2G54_RS12870	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
B2G54_RS12895	COG4964	Belongs to the GSP D family
B2G54_RS12955	COG0181	hydroxymethylbilane synthase activity
B2G54_RS12960	COG0861	Integral membrane protein TerC family
B2G54_RS12965	COG0861	Integral membrane protein TerC family
B2G54_RS12970	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
B2G54_RS12975	COG0045	succinate-CoA ligase (ADP-forming) activity
B2G54_RS12985	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
B2G54_RS12995	COG2137	regulation of response to DNA damage stimulus
B2G54_RS13000	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
B2G54_RS13020	COG1250	3-hydroxyacyl-CoA dehydrogenase
B2G54_RS13020	COG1024	Enoyl-CoA hydratase
B2G54_RS13025	COG3842	ATPase activity
B2G54_RS13040	COG1028	Short-chain dehydrogenase reductase Sdr
B2G54_RS13060	COG0583	DNA-binding transcription factor activity
B2G54_RS13065	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B2G54_RS13075	COG2974	May be involved in recombination
B2G54_RS13080	COG0540	Belongs to the ATCase OTCase family
B2G54_RS13155	COG0776	regulation of translation
B2G54_RS13160	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B2G54_RS13160	COG0072	phenylalanine-tRNA ligase activity
B2G54_RS13165	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
B2G54_RS13170	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
B2G54_RS13175	COG0291	Belongs to the bacterial ribosomal protein bL35 family
B2G54_RS13190	COG0756	dUTP diphosphatase activity
B2G54_RS13200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B2G54_RS13215	COG0500	methyltransferase
B2G54_RS13230	COG0586	Pfam SNARE associated Golgi protein
B2G54_RS13260	COG1609	Transcriptional regulator
B2G54_RS13265	COG4172	Belongs to the ABC transporter superfamily
B2G54_RS13270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B2G54_RS13275	COG0601	transmembrane transport
B2G54_RS13280	COG0747	negative chemotaxis
B2G54_RS13295	COG1280	lysine exporter protein (LysE YggA)
B2G54_RS13310	COG2814	Major facilitator Superfamily
B2G54_RS13340	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
B2G54_RS13360	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
B2G54_RS13385	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B2G54_RS13390	COG1116	anion transmembrane transporter activity
B2G54_RS13400	COG1228	amidohydrolase
B2G54_RS13415	COG0477	Major facilitator Superfamily
B2G54_RS13425	COG3550	peptidyl-serine autophosphorylation
B2G54_RS13440	COG0518	GMP synthase (glutamine-hydrolyzing) activity
B2G54_RS13440	COG0519	Catalyzes the synthesis of GMP from XMP
B2G54_RS13485	COG0420	3'-5' exonuclease activity
B2G54_RS13490	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B2G54_RS13520	COG0395	ABC-type sugar transport system, permease component
B2G54_RS13530	COG3842	ATPase activity
B2G54_RS13555	COG3181	Tripartite tricarboxylate transporter family receptor
B2G54_RS13590	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B2G54_RS13615	COG0602	queuosine metabolic process
B2G54_RS13620	COG0720	synthase
B2G54_RS13625	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
B2G54_RS13630	COG0235	Class ii aldolase
B2G54_RS13655	COG3064	Membrane
B2G54_RS13655	COG3210	domain, Protein
B2G54_RS13655	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
B2G54_RS13660	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
B2G54_RS13660	COG0047	phosphoribosylformylglycinamidine synthase activity
B2G54_RS13665	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
B2G54_RS13670	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
B2G54_RS13670	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
B2G54_RS13675	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B2G54_RS13700	COG3539	Fimbrial protein
B2G54_RS13710	COG2050	protein possibly involved in aromatic compounds catabolism
B2G54_RS13715	COG1024	Enoyl-CoA hydratase
B2G54_RS13720	COG1012	belongs to the aldehyde dehydrogenase family
B2G54_RS13730	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B2G54_RS13735	COG2151	metal-sulfur cluster biosynthetic enzyme
B2G54_RS13740	COG3396	Phenylacetate-CoA oxygenase
B2G54_RS13745	COG3460	Phenylacetate-CoA oxygenase
B2G54_RS13750	COG3396	Phenylacetate-CoA oxygenase
B2G54_RS13755	COG3327	negative regulation of DNA-templated transcription, initiation
B2G54_RS13765	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
B2G54_RS13770	COG0501	Belongs to the peptidase M48B family
B2G54_RS13775	COG1162	GTPase activity
B2G54_RS13780	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B2G54_RS13785	COG0601	transmembrane transport
B2G54_RS13790	COG0747	negative chemotaxis
B2G54_RS13835	COG0668	transmembrane transport
B2G54_RS13840	COG0165	Argininosuccinate lyase
B2G54_RS13860	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
B2G54_RS13865	COG0303	'Molybdopterin
B2G54_RS13870	COG0521	Mo-molybdopterin cofactor biosynthetic process
B2G54_RS13885	COG0315	cyclic pyranopterin monophosphate synthase activity
B2G54_RS13895	COG0412	Dienelactone hydrolase
B2G54_RS13905	COG0678	peroxiredoxin activity
B2G54_RS13915	COG0697	spore germination
B2G54_RS13920	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
B2G54_RS13945	COG0789	Transcriptional regulator
B2G54_RS13960	COG1028	Short-chain dehydrogenase reductase Sdr
B2G54_RS13970	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
B2G54_RS13975	COG1845	cytochrome c oxidase, subunit III
B2G54_RS13980	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B2G54_RS13990	COG0477	Major facilitator Superfamily
B2G54_RS14020	COG3468	outer membrane autotransporter barrel domain protein
B2G54_RS14030	COG1309	transcriptional regulator
B2G54_RS14035	COG2271	Major facilitator Superfamily
B2G54_RS14070	COG0506	proline dehydrogenase activity
B2G54_RS14070	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
B2G54_RS14070	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
B2G54_RS14080	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
B2G54_RS14080	COG3008	intermembrane lipid transfer
B2G54_RS14085	COG2995	paraquat-inducible protein a
B2G54_RS14090	COG0542	response to heat
B2G54_RS14095	COG4953	penicillin-binding protein 1C
B2G54_RS14105	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
B2G54_RS14110	COG1278	Cold shock
B2G54_RS14120	COG0183	Belongs to the thiolase family
B2G54_RS14125	COG0038	chloride channel
B2G54_RS14130	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
B2G54_RS14135	COG1570	exodeoxyribonuclease VII activity
B2G54_RS14145	COG0811	peptide transport
B2G54_RS14150	COG0848	biopolymer transport protein
B2G54_RS14155	COG1663	tetraacyldisaccharide 4'-kinase activity
B2G54_RS14160	COG2835	tetraacyldisaccharide 4'-kinase activity
B2G54_RS14165	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
B2G54_RS14170	COG0563	adenylate kinase activity
B2G54_RS14180	COG0728	peptidoglycan biosynthetic process
B2G54_RS14190	COG0268	Binds directly to 16S ribosomal RNA
B2G54_RS14220	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
B2G54_RS14245	COG0436	Aminotransferase
B2G54_RS14250	COG3737	Protein of unknown function (DUF498/DUF598)
B2G54_RS14255	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
B2G54_RS14260	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
B2G54_RS14265	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
B2G54_RS14275	COG0305	Participates in initiation and elongation during chromosome replication
B2G54_RS14285	COG0359	binds to the 23S rRNA
B2G54_RS14290	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
B2G54_RS14295	COG2965	DNA replication, synthesis of RNA primer
B2G54_RS14300	COG0360	Binds together with S18 to 16S ribosomal RNA
B2G54_RS14305	COG1469	GTP cyclohydrolase I activity
B2G54_RS14310	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
B2G54_RS14315	COG0142	geranyltranstransferase activity
B2G54_RS14320	COG1722	exodeoxyribonuclease VII activity
B2G54_RS14330	COG3181	Tripartite tricarboxylate transporter family receptor
B2G54_RS14350	COG2239	Acts as a magnesium transporter
B2G54_RS14360	COG2855	membrane
B2G54_RS14370	COG1473	amidohydrolase
B2G54_RS14375	COG0318	PFAM AMP-dependent synthetase and ligase
B2G54_RS14400	COG1501	Belongs to the glycosyl hydrolase 31 family
B2G54_RS14405	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
B2G54_RS14410	COG2011	ABC-type metal ion transport system permease component
B2G54_RS14430	COG1454	alcohol dehydrogenase
B2G54_RS14460	COG2186	Transcriptional regulator
B2G54_RS14465	COG3181	Tripartite tricarboxylate transporter family receptor
B2G54_RS14485	COG1175	transmembrane transport
B2G54_RS14490	COG0395	ABC-type sugar transport system, permease component
B2G54_RS14495	COG3842	ATPase activity
B2G54_RS14500	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B2G54_RS14510	COG1653	transport
B2G54_RS14530	COG2818	Glycosylase
B2G54_RS14535	COG2982	Protein involved in outer membrane biogenesis
B2G54_RS14540	COG1309	transcriptional regulator
B2G54_RS14545	COG1028	Short-chain dehydrogenase reductase Sdr
B2G54_RS14595	COG0583	DNA-binding transcription factor activity
B2G54_RS14600	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
B2G54_RS14605	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
B2G54_RS14620	COG1028	Short-chain dehydrogenase reductase Sdr
B2G54_RS14625	COG0477	Major facilitator Superfamily
B2G54_RS14635	COG0583	DNA-binding transcription factor activity
B2G54_RS14640	COG1448	Aminotransferase
B2G54_RS14645	COG1418	mRNA catabolic process
B2G54_RS14670	COG1063	alcohol dehydrogenase
B2G54_RS14690	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B2G54_RS14700	COG0318	PFAM AMP-dependent synthetase and ligase
B2G54_RS14710	COG1522	sequence-specific DNA binding
B2G54_RS14715	COG3181	Tripartite tricarboxylate transporter family receptor
B2G54_RS14720	COG0307	riboflavin synthase, alpha
B2G54_RS14725	COG0154	amidase activity
B2G54_RS14745	COG2807	transmembrane transport
B2G54_RS14750	COG0590	tRNA wobble adenosine to inosine editing
B2G54_RS14760	COG0583	DNA-binding transcription factor activity
B2G54_RS14795	COG3909	cytochrome
B2G54_RS14800	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
B2G54_RS14805	COG0625	glutathione transferase activity
B2G54_RS14810	COG0730	response to heat
B2G54_RS14815	COG0482	sulfurtransferase activity
B2G54_RS14820	COG0583	DNA-binding transcription factor activity
B2G54_RS14840	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
B2G54_RS14865	COG2819	hydrolase of the alpha beta superfamily
B2G54_RS14870	COG0247	lactate metabolic process
B2G54_RS14875	COG0277	FAD linked oxidase domain protein
B2G54_RS14880	COG0277	FAD linked oxidase domain protein
B2G54_RS14885	COG0277	FAD linked oxidase domain protein
B2G54_RS14890	COG3210	domain, Protein
B2G54_RS14890	COG3210	domain, Protein
B2G54_RS14890	COG3064	Membrane
B2G54_RS14890	COG3064	Membrane
B2G54_RS14890	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
B2G54_RS14890	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
B2G54_RS14895	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
B2G54_RS14900	COG0312	modulator of DNA gyrase
B2G54_RS14935	COG1666	GTP binding
B2G54_RS14980	COG3220	belongs to the UPF0276 family
B2G54_RS15000	COG0640	Transcriptional regulator
B2G54_RS15005	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
B2G54_RS15010	COG1845	cytochrome c oxidase, subunit III
B2G54_RS15015	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B2G54_RS15025	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
B2G54_RS15060	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B2G54_RS15065	COG0583	DNA-binding transcription factor activity
B2G54_RS15095	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B2G54_RS15095	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B2G54_RS15110	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
B2G54_RS15115	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
B2G54_RS15125	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
B2G54_RS15140	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
B2G54_RS15145	COG0316	Belongs to the HesB IscA family
B2G54_RS15155	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
B2G54_RS15160	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
B2G54_RS15165	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
B2G54_RS15170	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
B2G54_RS15175	COG0312	modulator of DNA gyrase
B2G54_RS15180	COG3028	Belongs to the UPF0307 family
B2G54_RS15195	COG1116	anion transmembrane transporter activity
B2G54_RS15200	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B2G54_RS15205	COG1335	isochorismatase
B2G54_RS15210	COG0346	lactoylglutathione lyase activity
B2G54_RS15215	COG0513	Belongs to the DEAD box helicase family
B2G54_RS15220	COG3069	C4-dicarboxylate transmembrane transporter activity
B2G54_RS15225	COG1802	Transcriptional regulator
B2G54_RS15240	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B2G54_RS15240	COG0045	succinate-CoA ligase (ADP-forming) activity
B2G54_RS15240	COG1042	CoA-binding domain protein
B2G54_RS15245	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
B2G54_RS15260	COG1522	sequence-specific DNA binding
B2G54_RS15295	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B2G54_RS15300	COG1696	Membrane protein involved in D-alanine export
B2G54_RS15325	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B2G54_RS15335	COG2264	protein methyltransferase activity
B2G54_RS15340	COG0439	Biotin carboxylase
B2G54_RS15345	COG0511	ligase activity, forming carbon-carbon bonds
B2G54_RS15350	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
B2G54_RS15355	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B2G54_RS15360	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
B2G54_RS15365	COG3150	esterase
B2G54_RS15370	COG0557	exoribonuclease II activity
B2G54_RS15380	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
B2G54_RS15405	COG1522	sequence-specific DNA binding
B2G54_RS15410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B2G54_RS15415	COG1028	Short-chain dehydrogenase reductase Sdr
B2G54_RS15435	COG0653	protein targeting
B2G54_RS15440	COG0739	heme binding
B2G54_RS15450	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
B2G54_RS15455	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
B2G54_RS15465	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
B2G54_RS15470	COG1181	Belongs to the D-alanine--D-alanine ligase family
B2G54_RS15475	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
B2G54_RS15480	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
B2G54_RS15490	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
B2G54_RS15495	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B2G54_RS15500	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
B2G54_RS15510	COG3116	cell division
B2G54_RS15515	COG0275	rRNA processing
B2G54_RS15520	COG2001	Belongs to the MraZ family
B2G54_RS15530	COG0488	(ABC) transporter
B2G54_RS15535	COG0418	dihydroorotase activity
B2G54_RS15540	COG1473	amidohydrolase
B2G54_RS15590	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B2G54_RS15595	COG4654	Cytochrome c, class I
B2G54_RS15600	COG0129	dihydroxy-acid dehydratase activity
B2G54_RS15605	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
B2G54_RS15655	COG2084	Dehydrogenase
B2G54_RS15660	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
B2G54_RS15670	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
B2G54_RS15675	COG0513	Belongs to the DEAD box helicase family
B2G54_RS15685	COG0617	tRNA 3'-terminal CCA addition
B2G54_RS15700	COG0477	Major facilitator Superfamily
B2G54_RS15710	COG0583	DNA-binding transcription factor activity
B2G54_RS15725	COG1950	PFAM Membrane protein of
B2G54_RS15730	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
B2G54_RS15745	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
B2G54_RS15755	COG1560	Kdo2-lipid A biosynthetic process
B2G54_RS15760	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
B2G54_RS15770	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
B2G54_RS15780	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
B2G54_RS15790	COG0803	Belongs to the bacterial solute-binding protein 9 family
B2G54_RS15810	COG0735	belongs to the Fur family
B2G54_RS15815	COG0523	cobalamin synthesis protein
B2G54_RS15825	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
B2G54_RS15830	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
B2G54_RS15840	COG2096	Adenosyltransferase
B2G54_RS15850	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B2G54_RS15855	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
B2G54_RS15915	COG1280	lysine exporter protein (LysE YggA)
B2G54_RS15930	COG0405	Gamma-glutamyltransferase
B2G54_RS15940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B2G54_RS15985	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
B2G54_RS16010	COG0582	viral genome integration into host DNA
B2G54_RS16015	COG0012	GTP binding
B2G54_RS16025	COG0193	aminoacyl-tRNA hydrolase activity
B2G54_RS16030	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
B2G54_RS16035	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
B2G54_RS16045	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
B2G54_RS16050	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
B2G54_RS16060	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
B2G54_RS16085	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
B2G54_RS16095	COG1368	sulfuric ester hydrolase activity
B2G54_RS16100	COG0642	Histidine kinase
B2G54_RS16105	COG0745	RESPONSE REGULATOR receiver
B2G54_RS16110	COG0277	FAD linked oxidase domain protein
B2G54_RS16125	COG0166	Belongs to the GPI family
B2G54_RS16130	COG0438	transferase activity, transferring glycosyl groups
B2G54_RS16135	COG0438	transferase activity, transferring glycosyl groups
B2G54_RS16150	COG0438	transferase activity, transferring glycosyl groups
B2G54_RS16165	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
B2G54_RS16170	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B2G54_RS16175	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
B2G54_RS16185	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
B2G54_RS16195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B2G54_RS16200	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B2G54_RS16210	COG0747	negative chemotaxis
B2G54_RS16215	COG0601	transmembrane transport
B2G54_RS16220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B2G54_RS16240	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
B2G54_RS16245	COG0830	nickel cation binding
B2G54_RS16255	COG0804	urea catabolic process
B2G54_RS16260	COG0832	Belongs to the urease beta subunit family
B2G54_RS16270	COG0831	urea catabolic process
B2G54_RS16275	COG0829	nickel cation binding
B2G54_RS16285	COG0633	Ferredoxin
B2G54_RS16300	COG2188	Transcriptional regulator
B2G54_RS16325	COG2719	SpoVR family
B2G54_RS16330	COG2718	Belongs to the UPF0229 family
B2G54_RS16350	COG1028	Short-chain dehydrogenase reductase Sdr
B2G54_RS16355	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B2G54_RS16370	COG1960	acyl-CoA dehydrogenase activity
B2G54_RS16415	COG0183	Belongs to the thiolase family
B2G54_RS16420	COG2030	dehydratase
B2G54_RS16470	COG0328	RNA-DNA hybrid ribonuclease activity
B2G54_RS16475	COG2226	methyltransferase
B2G54_RS16480	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B2G54_RS16485	COG1388	LysM domain
B2G54_RS16485	COG0741	lytic transglycosylase activity
B2G54_RS16505	COG2979	Protein of unknown function (DUF533)
B2G54_RS16540	COG1271	oxidase subunit
B2G54_RS16545	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
B2G54_RS16550	COG0850	regulation of cytokinetic process
B2G54_RS16555	COG2894	cell division
B2G54_RS16560	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
B2G54_RS16580	COG0488	(ABC) transporter
B2G54_RS16595	COG0601	transmembrane transport
B2G54_RS16605	COG1215	transferase activity, transferring glycosyl groups
B2G54_RS16620	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
B2G54_RS16630	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B2G54_RS16650	COG0318	PFAM AMP-dependent synthetase and ligase
B2G54_RS16655	COG2188	Transcriptional regulator
B2G54_RS16660	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
B2G54_RS16665	COG2814	Major facilitator Superfamily
B2G54_RS16675	COG0259	pyridoxamine-phosphate oxidase activity
B2G54_RS16680	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B2G54_RS16695	COG0583	DNA-binding transcription factor activity
B2G54_RS16700	COG1960	acyl-CoA dehydrogenase activity
B2G54_RS16720	COG0134	indole-3-glycerol-phosphate synthase activity
B2G54_RS16725	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
B2G54_RS16730	COG0512	Glutamine amidotransferase of anthranilate synthase
B2G54_RS16740	COG0546	phosphoglycolate phosphatase activity
B2G54_RS16745	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
B2G54_RS16750	COG2967	ApaG domain
B2G54_RS16755	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
B2G54_RS16760	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B2G54_RS16765	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
B2G54_RS16770	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B2G54_RS16780	COG0037	tRNA processing
B2G54_RS16790	COG3634	alkyl hydroperoxide reductase activity
B2G54_RS16795	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B2G54_RS16800	COG1024	Enoyl-CoA hydratase
B2G54_RS16825	COG0356	it plays a direct role in the translocation of protons across the membrane
B2G54_RS16835	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
B2G54_RS16840	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
B2G54_RS16845	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
B2G54_RS16850	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
B2G54_RS16855	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
B2G54_RS16860	COG0355	proton-transporting ATP synthase activity, rotational mechanism
B2G54_RS16870	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
B2G54_RS16875	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
B2G54_RS16880	COG0210	DNA helicase
B2G54_RS16890	COG2195	Cleaves the N-terminal amino acid of tripeptides
B2G54_RS16900	COG4172	Belongs to the ABC transporter superfamily
B2G54_RS16905	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B2G54_RS16910	COG0601	transmembrane transport
B2G54_RS16930	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
B2G54_RS16935	COG1024	Enoyl-CoA hydratase
B2G54_RS16940	COG1024	Enoyl-CoA hydratase
B2G54_RS16965	COG1250	3-hydroxyacyl-CoA dehydrogenase
B2G54_RS16995	COG2132	Multicopper oxidase
B2G54_RS17005	COG1250	3-hydroxyacyl-CoA dehydrogenase
B2G54_RS17005	COG1024	Enoyl-CoA hydratase
B2G54_RS17015	COG1414	Transcriptional regulator
B2G54_RS17025	COG0154	amidase activity
B2G54_RS17045	COG2154	pterin-4-alpha-carbinolamine dehydratase
B2G54_RS17055	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
B2G54_RS17065	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
B2G54_RS17070	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B2G54_RS17075	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
B2G54_RS17080	COG1929	Belongs to the glycerate kinase type-1 family
B2G54_RS17085	COG0469	pyruvate kinase activity
B2G54_RS17090	COG0700	Nucleoside recognition
B2G54_RS17125	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
B2G54_RS17130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B2G54_RS17145	COG0823	Involved in the tonB-independent uptake of proteins
B2G54_RS17155	COG0848	biopolymer transport protein
B2G54_RS17160	COG0811	peptide transport
B2G54_RS17165	COG0824	Thioesterase
B2G54_RS17170	COG0442	prolyl-tRNA aminoacylation
B2G54_RS17175	COG0494	nUDIX hydrolase
B2G54_RS17190	COG2135	peptidase activity
B2G54_RS17260	COG1196	nuclear chromosome segregation
B2G54_RS17415	COG0513	Belongs to the DEAD box helicase family
B2G54_RS17445	COG0429	hydrolase of the alpha beta-hydrolase fold
B2G54_RS17450	COG4783	chaperone-mediated protein folding
B2G54_RS17465	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
B2G54_RS17495	COG0006	proline dipeptidase activity
B2G54_RS17505	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B2G54_RS17525	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
B2G54_RS17530	COG0632	four-way junction helicase activity
B2G54_RS17545	COG2255	four-way junction helicase activity
B2G54_RS17550	COG0514	ATP-dependent DNA helicase (RecQ)
B2G54_RS17565	COG0288	reversible hydration of carbon dioxide
B2G54_RS17570	COG0154	amidase activity
B2G54_RS17580	COG4211	Belongs to the binding-protein-dependent transport system permease family
B2G54_RS17610	COG1464	Belongs to the NlpA lipoprotein family
B2G54_RS17625	COG1058	Belongs to the CinA family
B2G54_RS17625	COG1546	Belongs to the CinA family
B2G54_RS17630	COG1414	Transcriptional regulator
B2G54_RS17650	COG0167	dihydroorotate dehydrogenase activity
B2G54_RS17655	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
B2G54_RS17660	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
B2G54_RS17670	COG0583	DNA-binding transcription factor activity
B2G54_RS17730	COG0281	malic enzyme
B2G54_RS17730	COG0280	phosphate acetyltransferase
B2G54_RS17740	COG0601	transmembrane transport
B2G54_RS17745	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B2G54_RS17750	COG4172	Belongs to the ABC transporter superfamily
B2G54_RS17780	COG0640	Transcriptional regulator
B2G54_RS17795	COG3135	benzoate transporter
B2G54_RS17800	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
B2G54_RS17805	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
B2G54_RS17810	COG0742	ribosomal rna small subunit methyltransferase
B2G54_RS17825	COG3639	organic phosphonate transmembrane transporter activity
B2G54_RS17830	COG3639	organic phosphonate transmembrane transporter activity
B2G54_RS17835	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
B2G54_RS17870	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
B2G54_RS17875	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B2G54_RS17885	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
B2G54_RS17890	COG1058	Belongs to the CinA family
B2G54_RS17890	COG1546	Belongs to the CinA family
B2G54_RS17895	COG0284	orotidine-5'-phosphate decarboxylase activity
B2G54_RS17900	COG1252	NADH dehydrogenase
B2G54_RS17915	COG3468	outer membrane autotransporter barrel domain protein
B2G54_RS17920	COG0459	protein refolding
B2G54_RS17925	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
B2G54_RS17945	COG1053	succinate dehydrogenase
B2G54_RS17955	COG0583	DNA-binding transcription factor activity
B2G54_RS17960	COG1053	succinate dehydrogenase
B2G54_RS17975	COG3706	GGDEF domain
B2G54_RS18015	COG1262	PFAM Formylglycine-generating sulfatase enzyme
B2G54_RS18020	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
B2G54_RS18030	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B2G54_RS18045	COG0069	glutamate synthase activity
B2G54_RS18050	COG2391	methyltransferase activity
B2G54_RS18055	COG0679	Auxin Efflux Carrier
B2G54_RS18080	COG0557	exoribonuclease II activity
B2G54_RS18085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B2G54_RS18095	COG3128	pkhd-type hydroxylase
B2G54_RS18100	COG0776	regulation of translation
B2G54_RS18130	COG0642	Histidine kinase
B2G54_RS18135	COG3158	transport of potassium into the cell
B2G54_RS18140	COG0137	argininosuccinate synthase activity
B2G54_RS18145	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
B2G54_RS18150	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B2G54_RS18160	COG0583	DNA-binding transcription factor activity
B2G54_RS18170	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B2G54_RS18190	COG2186	Transcriptional regulator
B2G54_RS18200	COG2223	nitrite transmembrane transporter activity
B2G54_RS18210	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B2G54_RS18215	COG0450	alkyl hydroperoxide reductase
B2G54_RS18235	COG1214	PFAM Peptidase M22, glycoprotease
B2G54_RS18240	COG1573	uracil-dna glycosylase
B2G54_RS18245	COG0477	Major facilitator Superfamily
B2G54_RS18250	COG1196	nuclear chromosome segregation
B2G54_RS18260	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
B2G54_RS18265	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B2G54_RS18280	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B2G54_RS18285	COG1122	ATPase activity
B2G54_RS18290	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
B2G54_RS18295	COG1268	BioY protein
B2G54_RS18315	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B2G54_RS18350	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
B2G54_RS18355	COG2878	Part of a membrane complex involved in electron transport
B2G54_RS18370	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
B2G54_RS18375	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
B2G54_RS18380	COG0251	oxidation-reduction process
B2G54_RS18390	COG3228	Belongs to the MtfA family
B2G54_RS18395	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B2G54_RS18405	COG0133	tryptophan synthase activity
B2G54_RS18410	COG0159	tryptophan synthase activity
B2G54_RS18415	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
B2G54_RS18420	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
B2G54_RS18435	COG4206	TonB-dependent receptor
B2G54_RS18440	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B2G54_RS18445	COG2022	thiamine diphosphate biosynthetic process
B2G54_RS18450	COG0351	phosphomethylpyrimidine kinase
B2G54_RS18455	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
B2G54_RS18470	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
B2G54_RS18480	COG0628	permease
B2G54_RS18490	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
B2G54_RS18500	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
B2G54_RS18505	COG0049	tRNA binding
B2G54_RS18510	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
B2G54_RS18515	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
B2G54_RS18520	COG0051	transcription antitermination factor activity, RNA binding
B2G54_RS18525	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
B2G54_RS18530	COG0088	Forms part of the polypeptide exit tunnel
B2G54_RS18535	COG0089	rRNA binding
B2G54_RS18540	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
B2G54_RS18545	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
B2G54_RS18550	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
B2G54_RS18555	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
B2G54_RS18560	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
B2G54_RS18565	COG0255	Belongs to the universal ribosomal protein uL29 family
B2G54_RS18570	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
B2G54_RS18590	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
B2G54_RS18595	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
B2G54_RS18600	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
B2G54_RS18605	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
B2G54_RS18610	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
B2G54_RS18615	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
B2G54_RS18620	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
B2G54_RS18625	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
B2G54_RS18630	COG1841	ribosomal large subunit assembly
B2G54_RS18635	COG0200	Binds to the 23S rRNA
B2G54_RS18640	COG0201	protein transport
B2G54_RS18645	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
B2G54_RS18650	COG0257	Belongs to the bacterial ribosomal protein bL36 family
B2G54_RS18655	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
B2G54_RS18660	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
B2G54_RS18665	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
B2G54_RS18670	COG0202	RNA polymerase activity
B2G54_RS18675	COG0203	ribosomal protein L17
B2G54_RS18680	COG0537	adenosine 5'-monophosphoramidase activity
B2G54_RS18685	COG1324	tolerance protein
B2G54_RS18690	COG4232	protein-disulfide reductase activity
B2G54_RS18705	COG0218	Necessary for normal cell division and for the maintenance of normal septation
B2G54_RS18715	COG1333	cytochrome c biogenesis protein
B2G54_RS18720	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B2G54_RS18735	COG1965	Belongs to the frataxin family
B2G54_RS18745	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
B2G54_RS18750	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
B2G54_RS18755	COG0232	Belongs to the dGTPase family. Type 2 subfamily
B2G54_RS18770	COG2814	Major facilitator Superfamily
B2G54_RS18775	COG0629	single-stranded DNA binding
B2G54_RS18815	COG0402	S-adenosylhomocysteine deaminase activity
B2G54_RS18825	COG0438	transferase activity, transferring glycosyl groups
B2G54_RS18845	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B2G54_RS18870	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
B2G54_RS18875	COG2186	Transcriptional regulator
B2G54_RS18895	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B2G54_RS18900	COG1956	GAF domain-containing protein
B2G54_RS18905	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B2G54_RS18920	COG1652	LysM domain
B2G54_RS18935	COG0220	tRNA (guanine-N7-)-methyltransferase activity
B2G54_RS18950	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B2G54_RS18980	COG3181	Tripartite tricarboxylate transporter family receptor
B2G54_RS18995	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B2G54_RS19010	COG1024	Enoyl-CoA hydratase
B2G54_RS19025	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B2G54_RS19030	COG1309	transcriptional regulator
B2G54_RS19035	COG2816	NAD+ diphosphatase activity
B2G54_RS19040	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B2G54_RS19125	COG2814	Major facilitator Superfamily
B2G54_RS19130	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
B2G54_RS19150	COG1999	signal sequence binding
B2G54_RS19155	COG0109	protoheme IX farnesyltransferase activity
B2G54_RS19195	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B2G54_RS19215	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
B2G54_RS19220	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B2G54_RS19230	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
B2G54_RS19235	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
B2G54_RS19245	COG0070	glutamate synthase
B2G54_RS19245	COG0067	glutamate synthase
B2G54_RS19245	COG0069	glutamate synthase activity
B2G54_RS19255	COG3047	cAMP biosynthetic process
B2G54_RS19265	COG1127	ABC transporter
B2G54_RS19270	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
B2G54_RS19275	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
B2G54_RS19280	COG2853	Lipoprotein
B2G54_RS19295	COG0842	Transport permease protein
B2G54_RS19305	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
B2G54_RS19310	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
B2G54_RS19315	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
B2G54_RS19320	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
B2G54_RS19325	COG0131	Imidazoleglycerol-phosphate dehydratase
B2G54_RS19330	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
B2G54_RS19335	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
B2G54_RS19340	COG0107	imidazoleglycerol-phosphate synthase activity
B2G54_RS19345	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
B2G54_RS19350	COG0140	phosphoribosyl-ATP diphosphatase activity
B2G54_RS19355	COG0537	adenosine 5'-monophosphoramidase activity
B2G54_RS19360	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B2G54_RS19365	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B2G54_RS19380	COG3181	Tripartite tricarboxylate transporter family receptor
B2G54_RS19415	COG3702	type iv secretory pathway
B2G54_RS19420	COG3451	type IV secretory pathway VirB4
B2G54_RS19435	COG3736	Type IV secretory pathway, component VirB8
B2G54_RS19440	COG3504	Conjugal transfer protein
B2G54_RS19445	COG2948	multi-organism process
B2G54_RS19450	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
B2G54_RS19460	COG0697	spore germination
B2G54_RS19480	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
B2G54_RS19485	COG0747	negative chemotaxis
B2G54_RS19490	COG0601	transmembrane transport
B2G54_RS19495	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B2G54_RS19500	COG0444	Belongs to the ABC transporter superfamily
B2G54_RS19510	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
B2G54_RS19520	COG0494	nUDIX hydrolase
B2G54_RS19560	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
B2G54_RS19565	COG0237	dephospho-CoA kinase activity
B2G54_RS19570	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
B2G54_RS19585	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
B2G54_RS19590	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
B2G54_RS19600	COG0477	Major facilitator Superfamily
B2G54_RS19605	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
B2G54_RS19620	COG1126	abc transporter atp-binding protein
B2G54_RS19625	COG0765	amino acid transport
B2G54_RS19630	COG4597	amino acid ABC transporter
B2G54_RS19635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B2G54_RS19640	COG2884	Cell division ATP-binding protein ftsE
B2G54_RS19645	COG2177	Part of the ABC transporter FtsEX involved in
B2G54_RS19650	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
B2G54_RS19660	COG1194	a g-specific adenine glycosylase
B2G54_RS19670	COG2226	methyltransferase
B2G54_RS19680	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B2G54_RS19685	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B2G54_RS19700	COG1024	Enoyl-CoA hydratase
B2G54_RS19720	COG1024	Enoyl-CoA hydratase
B2G54_RS19725	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B2G54_RS19730	COG3181	Tripartite tricarboxylate transporter family receptor
B2G54_RS19740	COG0753	catalase activity
B2G54_RS19745	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B2G54_RS19750	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
B2G54_RS19760	COG2175	clavaminate synthase activity
B2G54_RS19765	COG1473	amidohydrolase
B2G54_RS19770	COG4608	Belongs to the ABC transporter superfamily
B2G54_RS19775	COG0444	Belongs to the ABC transporter superfamily
B2G54_RS19790	COG0747	negative chemotaxis
B2G54_RS19795	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
B2G54_RS19830	COG0436	Aminotransferase
B2G54_RS19835	COG1278	Cold shock