locus-tag	class	description
BBB39_RS00005	COG0445	tRNA wobble uridine modification
BBB39_RS00010	COG0357	Ribosomal RNA small subunit methyltransferase G
BBB39_RS00015	COG1192	Involved in chromosome partitioning
BBB39_RS00020	COG1475	DNA binding
BBB39_RS00025	COG0252	asparaginase activity
BBB39_RS00045	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BBB39_RS00055	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BBB39_RS00070	COG0081	regulation of translation
BBB39_RS00075	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BBB39_RS00080	COG0222	ribosome binding
BBB39_RS00085	COG0085	RNA polymerase activity
BBB39_RS00090	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BBB39_RS00125	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BBB39_RS00130	COG0049	tRNA binding
BBB39_RS00135	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BBB39_RS00140	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BBB39_RS00145	COG0051	transcription antitermination factor activity, RNA binding
BBB39_RS00150	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BBB39_RS00155	COG0088	Forms part of the polypeptide exit tunnel
BBB39_RS00160	COG0089	rRNA binding
BBB39_RS00165	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BBB39_RS00170	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BBB39_RS00175	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BBB39_RS00180	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BBB39_RS00185	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BBB39_RS00190	COG0255	Belongs to the universal ribosomal protein uL29 family
BBB39_RS00195	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BBB39_RS00215	COG0411	ABC transporter
BBB39_RS00225	COG2267	carboxylic ester hydrolase activity
BBB39_RS00245	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BBB39_RS00250	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BBB39_RS00255	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BBB39_RS00260	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BBB39_RS00265	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BBB39_RS00275	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BBB39_RS00280	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BBB39_RS00285	COG1841	ribosomal large subunit assembly
BBB39_RS00290	COG0200	Binds to the 23S rRNA
BBB39_RS00295	COG0201	protein transport
BBB39_RS00300	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BBB39_RS00305	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BBB39_RS00310	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BBB39_RS00315	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BBB39_RS00320	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BBB39_RS00325	COG0202	RNA polymerase activity
BBB39_RS00330	COG0203	ribosomal protein L17
BBB39_RS00340	COG1324	tolerance protein
BBB39_RS00345	COG4232	protein-disulfide reductase activity
BBB39_RS00355	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BBB39_RS00365	COG1333	cytochrome c biogenesis protein
BBB39_RS00370	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BBB39_RS00385	COG1965	Belongs to the frataxin family
BBB39_RS00395	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BBB39_RS00400	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BBB39_RS00405	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BBB39_RS00420	COG2814	Major facilitator Superfamily
BBB39_RS00430	COG2814	Major facilitator Superfamily
BBB39_RS00435	COG0583	DNA-binding transcription factor activity
BBB39_RS00450	COG0183	Belongs to the thiolase family
BBB39_RS00455	COG1960	acyl-CoA dehydrogenase activity
BBB39_RS00460	COG1024	Enoyl-CoA hydratase
BBB39_RS00475	COG0745	RESPONSE REGULATOR receiver
BBB39_RS00485	COG2197	response regulator
BBB39_RS00490	COG3850	Histidine kinase
BBB39_RS00495	COG1763	Mo-molybdopterin cofactor biosynthetic process
BBB39_RS00500	COG2181	nitrate reductase activity
BBB39_RS00505	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BBB39_RS00510	COG1140	nitrate reductase beta subunit
BBB39_RS00515	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BBB39_RS00520	COG2223	nitrite transmembrane transporter activity
BBB39_RS00550	COG0037	tRNA processing
BBB39_RS00560	COG0482	sulfurtransferase activity
BBB39_RS00605	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BBB39_RS00610	COG2186	Transcriptional regulator
BBB39_RS00625	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BBB39_RS00630	COG1956	GAF domain-containing protein
BBB39_RS00635	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BBB39_RS00660	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BBB39_RS00670	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BBB39_RS00680	COG0477	Major facilitator Superfamily
BBB39_RS00695	COG1088	dTDP-glucose 4,6-dehydratase activity
BBB39_RS00700	COG1091	dTDP-4-dehydrorhamnose reductase activity
BBB39_RS00705	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BBB39_RS00715	COG0859	PFAM glycosyl transferase family 9
BBB39_RS00725	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BBB39_RS00735	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BBB39_RS00760	COG1686	Belongs to the peptidase S11 family
BBB39_RS00770	COG2921	Belongs to the UPF0250 family
BBB39_RS00775	COG0321	lipoyl(octanoyl) transferase activity
BBB39_RS00780	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BBB39_RS00785	COG2096	Adenosyltransferase
BBB39_RS00795	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BBB39_RS00800	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BBB39_RS00810	COG0523	cobalamin synthesis protein
BBB39_RS00815	COG0735	belongs to the Fur family
BBB39_RS00820	COG1121	(ABC) transporter
BBB39_RS00825	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BBB39_RS00840	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
BBB39_RS00850	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BBB39_RS00860	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BBB39_RS00875	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BBB39_RS00890	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BBB39_RS00895	COG1950	PFAM Membrane protein of
BBB39_RS00900	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BBB39_RS00910	COG3220	belongs to the UPF0276 family
BBB39_RS00920	COG2259	Doxx family
BBB39_RS00935	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BBB39_RS00955	COG0513	Belongs to the DEAD box helicase family
BBB39_RS00960	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BBB39_RS00965	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BBB39_RS00985	COG0735	belongs to the Fur family
BBB39_RS01015	COG0640	Transcriptional regulator
BBB39_RS01075	COG0583	DNA-binding transcription factor activity
BBB39_RS01080	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BBB39_RS01085	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BBB39_RS01090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BBB39_RS01110	COG0758	DNA mediated transformation
BBB39_RS01125	COG1966	Carbon starvation protein
BBB39_RS01130	COG2879	small protein
BBB39_RS01135	COG1522	sequence-specific DNA binding
BBB39_RS01145	COG0242	peptide deformylase activity
BBB39_RS01150	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BBB39_RS01160	COG0546	phosphoglycolate phosphatase activity
BBB39_RS01170	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BBB39_RS01175	COG2188	Transcriptional regulator
BBB39_RS01190	COG1028	Short-chain dehydrogenase reductase Sdr
BBB39_RS01200	COG1960	acyl-CoA dehydrogenase activity
BBB39_RS01205	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BBB39_RS01220	COG2204	response regulator
BBB39_RS01220	COG2204	response regulator
BBB39_RS01225	COG0569	domain protein
BBB39_RS01230	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BBB39_RS01235	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
BBB39_RS01240	COG2226	methyltransferase
BBB39_RS01245	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BBB39_RS01255	COG3181	Tripartite tricarboxylate transporter family receptor
BBB39_RS01260	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BBB39_RS01265	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BBB39_RS01270	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BBB39_RS01275	COG1054	Belongs to the UPF0176 family
BBB39_RS01280	COG0588	phosphoglycerate mutase activity
BBB39_RS01285	COG4942	peptidase
BBB39_RS01290	COG0793	Belongs to the peptidase S41A family
BBB39_RS01295	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BBB39_RS01310	COG0861	Integral membrane protein TerC family
BBB39_RS01315	COG0583	DNA-binding transcription factor activity
BBB39_RS01325	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BBB39_RS01330	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BBB39_RS01350	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BBB39_RS01355	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BBB39_RS01360	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BBB39_RS01365	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BBB39_RS01370	COG0142	geranyltranstransferase activity
BBB39_RS01380	COG0154	amidase activity
BBB39_RS01390	COG1137	ATPase activity
BBB39_RS01415	COG1024	Enoyl-CoA hydratase
BBB39_RS01425	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BBB39_RS01440	COG1473	amidohydrolase
BBB39_RS01450	COG0583	DNA-binding transcription factor activity
BBB39_RS01455	COG0626	cystathionine gamma-synthase activity
BBB39_RS01460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BBB39_RS01465	COG0765	amino acid transport
BBB39_RS01470	COG0765	amino acid transport
BBB39_RS01475	COG1126	abc transporter atp-binding protein
BBB39_RS01480	COG3608	succinylglutamate desuccinylase aspartoacylase
BBB39_RS01485	COG1028	Short-chain dehydrogenase reductase Sdr
BBB39_RS01495	COG3608	succinylglutamate desuccinylase aspartoacylase
BBB39_RS01510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BBB39_RS01515	COG0765	amino acid transport
BBB39_RS01520	COG0765	amino acid transport
BBB39_RS01525	COG1126	abc transporter atp-binding protein
BBB39_RS01530	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BBB39_RS01545	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BBB39_RS01565	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BBB39_RS01570	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BBB39_RS01575	COG2890	protein-(glutamine-N5) methyltransferase activity
BBB39_RS01580	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BBB39_RS01600	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BBB39_RS01605	COG0288	reversible hydration of carbon dioxide
BBB39_RS01620	COG0596	Alpha beta hydrolase
BBB39_RS01630	COG4829	muconolactone delta-isomerase
BBB39_RS01635	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BBB39_RS01645	COG1414	Transcriptional regulator
BBB39_RS01650	COG1028	Short-chain dehydrogenase reductase Sdr
BBB39_RS01655	COG2031	fatty acid transporter
BBB39_RS01660	COG1250	3-hydroxyacyl-CoA dehydrogenase
BBB39_RS01665	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BBB39_RS01670	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BBB39_RS01675	COG0129	dihydroxy-acid dehydratase activity
BBB39_RS01680	COG3539	Fimbrial protein
BBB39_RS01685	COG3539	Fimbrial protein
BBB39_RS01690	COG3539	Fimbrial protein
BBB39_RS01700	COG3539	Fimbrial protein
BBB39_RS01705	COG3539	Fimbrial protein
BBB39_RS01710	COG3539	Fimbrial protein
BBB39_RS01715	COG3539	Fimbrial protein
BBB39_RS01720	COG3539	Fimbrial protein
BBB39_RS01725	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
BBB39_RS01745	COG0583	DNA-binding transcription factor activity
BBB39_RS01750	COG0628	permease
BBB39_RS01760	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BBB39_RS01780	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BBB39_RS01785	COG1653	transport
BBB39_RS01790	COG0395	ABC-type sugar transport system, permease component
BBB39_RS01795	COG1175	transmembrane transport
BBB39_RS01800	COG3842	ATPase activity
BBB39_RS01805	COG0546	phosphoglycolate phosphatase activity
BBB39_RS01835	COG1064	alcohol dehydrogenase
BBB39_RS01850	COG0583	DNA-binding transcription factor activity
BBB39_RS01875	COG2819	hydrolase of the alpha beta superfamily
BBB39_RS01885	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BBB39_RS01890	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BBB39_RS01895	COG3181	Tripartite tricarboxylate transporter family receptor
BBB39_RS01915	COG0235	Class ii aldolase
BBB39_RS01950	COG1177	transmembrane transport
BBB39_RS01955	COG0318	PFAM AMP-dependent synthetase and ligase
BBB39_RS01960	COG1024	Enoyl-CoA hydratase
BBB39_RS01965	COG0604	alcohol dehydrogenase
BBB39_RS01975	COG2130	NADP-dependent
BBB39_RS01990	COG0583	DNA-binding transcription factor activity
BBB39_RS01995	COG0625	glutathione transferase activity
BBB39_RS02000	COG1942	4-Oxalocrotonate Tautomerase
BBB39_RS02090	COG2233	PERMEase
BBB39_RS02095	COG0326	Molecular chaperone. Has ATPase activity
BBB39_RS02100	COG0625	glutathione transferase activity
BBB39_RS02120	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BBB39_RS02125	COG1652	LysM domain
BBB39_RS02140	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BBB39_RS02155	COG1028	Short-chain dehydrogenase reductase Sdr
BBB39_RS02160	COG4689	acetoacetate decarboxylase
BBB39_RS02170	COG0154	amidase activity
BBB39_RS02175	COG0477	Major facilitator Superfamily
BBB39_RS02185	COG0179	Fumarylacetoacetate (FAA) hydrolase
BBB39_RS02195	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BBB39_RS02205	COG1522	sequence-specific DNA binding
BBB39_RS02210	COG0583	DNA-binding transcription factor activity
BBB39_RS02215	COG0626	cystathionine gamma-synthase activity
BBB39_RS02220	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BBB39_RS02225	COG1028	Short-chain dehydrogenase reductase Sdr
BBB39_RS02235	COG3181	Tripartite tricarboxylate transporter family receptor
BBB39_RS02250	COG0019	diaminopimelate decarboxylase activity
BBB39_RS02275	COG0583	DNA-binding transcription factor activity
BBB39_RS02285	COG2084	Dehydrogenase
BBB39_RS02315	COG1028	Short-chain dehydrogenase reductase Sdr
BBB39_RS02330	COG3246	L-lysine catabolic process to acetate
BBB39_RS02340	COG1028	Short-chain dehydrogenase reductase Sdr
BBB39_RS02350	COG0583	DNA-binding transcription factor activity
BBB39_RS02395	COG1294	oxidase, subunit
BBB39_RS02400	COG1271	oxidase subunit
BBB39_RS02405	COG0583	DNA-binding transcription factor activity
BBB39_RS02410	COG1024	Enoyl-CoA hydratase
BBB39_RS02410	COG1250	3-hydroxyacyl-CoA dehydrogenase
BBB39_RS02415	COG0183	Belongs to the thiolase family
BBB39_RS02420	COG1960	acyl-CoA dehydrogenase activity
BBB39_RS02425	COG1960	acyl-CoA dehydrogenase activity
BBB39_RS02430	COG1024	Enoyl-CoA hydratase
BBB39_RS02435	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BBB39_RS02440	COG3181	Tripartite tricarboxylate transporter family receptor
BBB39_RS02455	COG0583	DNA-binding transcription factor activity
BBB39_RS02480	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BBB39_RS02505	COG0693	protein deglycase activity
BBB39_RS02520	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BBB39_RS02525	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
BBB39_RS02530	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BBB39_RS02535	COG2205	protein histidine kinase activity
BBB39_RS02540	COG0745	RESPONSE REGULATOR receiver
BBB39_RS02545	COG3976	FMN-binding domain protein
BBB39_RS02545	COG1053	succinate dehydrogenase
BBB39_RS02550	COG0477	Major facilitator Superfamily
BBB39_RS02555	COG0129	dihydroxy-acid dehydratase activity
BBB39_RS02560	COG2186	Transcriptional regulator
BBB39_RS02575	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BBB39_RS02580	COG3842	ATPase activity
BBB39_RS02595	COG2423	ornithine cyclodeaminase activity
BBB39_RS02605	COG1414	Transcriptional regulator
BBB39_RS02610	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BBB39_RS02625	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BBB39_RS02640	COG2204	response regulator
BBB39_RS02645	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BBB39_RS02660	COG0439	Biotin carboxylase
BBB39_RS02665	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BBB39_RS02675	COG0183	Belongs to the thiolase family
BBB39_RS02680	COG1024	Enoyl-CoA hydratase
BBB39_RS02680	COG1250	3-hydroxyacyl-CoA dehydrogenase
BBB39_RS02710	COG1028	Short-chain dehydrogenase reductase Sdr
BBB39_RS02715	COG1522	sequence-specific DNA binding
BBB39_RS02720	COG0010	Belongs to the arginase family
BBB39_RS02725	COG3539	Fimbrial protein
BBB39_RS02750	COG1054	Belongs to the UPF0176 family
BBB39_RS02755	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BBB39_RS02755	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BBB39_RS02765	COG0489	protein tyrosine kinase activity
BBB39_RS02780	COG0717	Belongs to the dCTP deaminase family
BBB39_RS02785	COG0456	acetyltransferase
BBB39_RS02800	COG2081	HI0933 family
BBB39_RS02805	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BBB39_RS02810	COG0509	glycine decarboxylation via glycine cleavage system
BBB39_RS02815	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BBB39_RS02815	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BBB39_RS02825	COG5339	Protein conserved in bacteria
BBB39_RS02840	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BBB39_RS02845	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BBB39_RS02865	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
BBB39_RS02870	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BBB39_RS02875	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BBB39_RS02890	COG0438	transferase activity, transferring glycosyl groups
BBB39_RS02905	COG0438	transferase activity, transferring glycosyl groups
BBB39_RS02910	COG0438	transferase activity, transferring glycosyl groups
BBB39_RS02915	COG0166	Belongs to the GPI family
BBB39_RS02930	COG0277	FAD linked oxidase domain protein
BBB39_RS02935	COG0745	RESPONSE REGULATOR receiver
BBB39_RS02940	COG0642	Histidine kinase
BBB39_RS02945	COG2186	Transcriptional regulator
BBB39_RS02950	COG1368	sulfuric ester hydrolase activity
BBB39_RS02955	COG4771	TonB-dependent receptor
BBB39_RS02955	COG1629	transport
BBB39_RS02965	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
BBB39_RS02980	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BBB39_RS02990	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BBB39_RS03000	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BBB39_RS03005	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BBB39_RS03015	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BBB39_RS03020	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BBB39_RS03025	COG0193	aminoacyl-tRNA hydrolase activity
BBB39_RS03035	COG0012	GTP binding
BBB39_RS03055	COG0784	Response regulator, receiver
BBB39_RS03055	COG2205	protein histidine kinase activity
BBB39_RS03060	COG2205	protein histidine kinase activity
BBB39_RS03060	COG0784	Response regulator, receiver
BBB39_RS03065	COG2197	response regulator
BBB39_RS03070	COG1113	amino acid transport
BBB39_RS03090	COG3121	Chaperone
BBB39_RS03130	COG3135	benzoate transporter
BBB39_RS03135	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BBB39_RS03140	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BBB39_RS03145	COG0742	ribosomal rna small subunit methyltransferase
BBB39_RS03155	COG0625	glutathione transferase activity
BBB39_RS03160	COG0477	Major facilitator Superfamily
BBB39_RS03180	COG3639	organic phosphonate transmembrane transporter activity
BBB39_RS03185	COG3639	organic phosphonate transmembrane transporter activity
BBB39_RS03190	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BBB39_RS03205	COG1414	Transcriptional regulator
BBB39_RS03220	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BBB39_RS03225	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BBB39_RS03230	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BBB39_RS03235	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BBB39_RS03240	COG1546	Belongs to the CinA family
BBB39_RS03245	COG0284	orotidine-5'-phosphate decarboxylase activity
BBB39_RS03250	COG1252	NADH dehydrogenase
BBB39_RS03255	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BBB39_RS03260	COG1295	ribonuclease BN
BBB39_RS03265	COG0459	protein refolding
BBB39_RS03270	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BBB39_RS03275	COG0583	DNA-binding transcription factor activity
BBB39_RS03290	COG2721	sulfolactate sulfo-lyase activity
BBB39_RS03300	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BBB39_RS03305	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BBB39_RS03310	COG3181	Tripartite tricarboxylate transporter family receptor
BBB39_RS03340	COG0698	ribose 5-phosphate isomerase
BBB39_RS03350	COG3395	kinase activity
BBB39_RS03355	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BBB39_RS03365	COG1028	Short-chain dehydrogenase reductase Sdr
BBB39_RS03375	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BBB39_RS03395	COG4133	protoheme IX ABC transporter activity
BBB39_RS03400	COG0833	amino acid
BBB39_RS03405	COG0833	amino acid
BBB39_RS03410	COG0513	Belongs to the DEAD box helicase family
BBB39_RS03425	COG2199	diguanylate cyclase activity
BBB39_RS03425	COG2203	Gaf domain
BBB39_RS03445	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BBB39_RS03450	COG0318	PFAM AMP-dependent synthetase and ligase
BBB39_RS03460	COG4566	intracellular signal transduction
BBB39_RS03480	COG0642	Histidine kinase
BBB39_RS03505	COG2814	Major facilitator Superfamily
BBB39_RS03505	COG0477	Major facilitator Superfamily
BBB39_RS03515	COG2375	cellular response to nickel ion
BBB39_RS03520	COG1695	Transcriptional regulator
BBB39_RS03530	COG0028	Belongs to the TPP enzyme family
BBB39_RS03535	COG0668	transmembrane transport
BBB39_RS03540	COG0668	transmembrane transport
BBB39_RS03545	COG1396	sequence-specific DNA binding
BBB39_RS03555	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BBB39_RS03565	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BBB39_RS03570	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BBB39_RS03575	COG1028	Short-chain dehydrogenase reductase Sdr
BBB39_RS03580	COG2271	Major facilitator Superfamily
BBB39_RS03610	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BBB39_RS03615	COG1024	Enoyl-CoA hydratase
BBB39_RS03625	COG0431	NADPH-dependent FMN reductase
BBB39_RS03655	COG1802	Transcriptional regulator
BBB39_RS03670	COG0477	Major facilitator Superfamily
BBB39_RS03675	COG1028	Short-chain dehydrogenase reductase Sdr
BBB39_RS03690	COG3181	Tripartite tricarboxylate transporter family receptor
BBB39_RS03700	COG3181	Tripartite tricarboxylate transporter family receptor
BBB39_RS03705	COG0583	DNA-binding transcription factor activity
BBB39_RS03715	COG1999	signal sequence binding
BBB39_RS03750	COG3048	D-serine ammonia-lyase activity
BBB39_RS03760	COG2207	Transcriptional regulator
BBB39_RS03770	COG2814	Major facilitator Superfamily
BBB39_RS03780	COG0583	DNA-binding transcription factor activity
BBB39_RS03790	COG0154	amidase activity
BBB39_RS03800	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BBB39_RS03805	COG0028	Belongs to the TPP enzyme family
BBB39_RS03825	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BBB39_RS03830	COG0640	Transcriptional regulator
BBB39_RS03865	COG3181	Tripartite tricarboxylate transporter family receptor
BBB39_RS03870	COG0028	Belongs to the TPP enzyme family
BBB39_RS03880	COG0025	NhaP-type Na H and K H
BBB39_RS03905	COG0076	glutamate decarboxylase activity
BBB39_RS03920	COG1228	amidohydrolase
BBB39_RS03945	COG0410	ABC transporter
BBB39_RS03970	COG1414	Transcriptional regulator
BBB39_RS03980	COG0786	glutamate:sodium symporter activity
BBB39_RS04000	COG1609	Transcriptional regulator
BBB39_RS04005	COG4172	Belongs to the ABC transporter superfamily
BBB39_RS04010	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BBB39_RS04015	COG0601	transmembrane transport
BBB39_RS04035	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BBB39_RS04065	COG2814	Major facilitator Superfamily
BBB39_RS04070	COG0625	glutathione transferase activity
BBB39_RS04075	COG3181	Tripartite tricarboxylate transporter family receptor
BBB39_RS04080	COG2272	Belongs to the type-B carboxylesterase lipase family
BBB39_RS04095	COG0251	oxidation-reduction process
BBB39_RS04105	COG0747	negative chemotaxis
BBB39_RS04110	COG0601	transmembrane transport
BBB39_RS04115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BBB39_RS04120	COG0444	Belongs to the ABC transporter superfamily
BBB39_RS04125	COG4608	Belongs to the ABC transporter superfamily
BBB39_RS04130	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BBB39_RS04150	COG1012	belongs to the aldehyde dehydrogenase family
BBB39_RS04155	COG3284	Transcriptional regulator
BBB39_RS04175	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BBB39_RS04190	COG2885	chlorophyll binding
BBB39_RS04210	COG5265	(ABC) transporter
BBB39_RS04255	COG0456	acetyltransferase
BBB39_RS04265	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BBB39_RS04275	COG1408	metallophosphoesterase
BBB39_RS04285	COG2610	gluconate transmembrane transporter activity
BBB39_RS04290	COG2070	2-Nitropropane dioxygenase
BBB39_RS04300	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BBB39_RS04315	COG0747	negative chemotaxis
BBB39_RS04320	COG0405	Gamma-glutamyltransferase
BBB39_RS04335	COG0583	DNA-binding transcription factor activity
BBB39_RS04340	COG1380	Effector of murein hydrolase LrgA
BBB39_RS04345	COG1346	cytolysis
BBB39_RS04360	COG2132	Multicopper oxidase
BBB39_RS04365	COG0783	Belongs to the Dps family
BBB39_RS04385	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BBB39_RS04390	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BBB39_RS04395	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BBB39_RS04400	COG1845	cytochrome c oxidase, subunit III
BBB39_RS04420	COG1666	GTP binding
BBB39_RS04430	COG1028	Short-chain dehydrogenase reductase Sdr
BBB39_RS04440	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BBB39_RS04445	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BBB39_RS04450	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BBB39_RS04455	COG0746	molybdenum cofactor guanylyltransferase activity
BBB39_RS04460	COG0303	'Molybdopterin
BBB39_RS04465	COG0521	Mo-molybdopterin cofactor biosynthetic process
BBB39_RS04480	COG0315	cyclic pyranopterin monophosphate synthase activity
BBB39_RS04490	COG0678	peroxiredoxin activity
BBB39_RS04500	COG0697	spore germination
BBB39_RS04505	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BBB39_RS04545	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BBB39_RS04550	COG1702	phosphate starvation-inducible protein PhoH
BBB39_RS04555	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BBB39_RS04560	COG4535	Mg2 and Co2 transporter CorC
BBB39_RS04565	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BBB39_RS04570	COG0667	Aldo Keto reductase
BBB39_RS04590	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BBB39_RS04595	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BBB39_RS04600	COG1862	Preprotein translocase
BBB39_RS04605	COG0343	queuine tRNA-ribosyltransferase activity
BBB39_RS04610	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BBB39_RS04615	COG2027	D-alanyl-D-alanine carboxypeptidase
BBB39_RS04620	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BBB39_RS04625	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BBB39_RS04625	COG1648	precorrin-2 dehydrogenase activity
BBB39_RS04635	COG4575	ribosome binding
BBB39_RS04660	COG0318	PFAM AMP-dependent synthetase and ligase
BBB39_RS04675	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BBB39_RS04680	COG0741	lytic transglycosylase activity
BBB39_RS04685	COG0436	Aminotransferase
BBB39_RS04690	COG0280	phosphate acetyltransferase
BBB39_RS04690	COG0281	malic enzyme
BBB39_RS04705	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BBB39_RS04710	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BBB39_RS04715	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BBB39_RS04720	COG0126	phosphoglycerate kinase activity
BBB39_RS04750	COG1120	ATPase activity
BBB39_RS04755	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BBB39_RS04760	COG4592	Periplasmic binding protein
BBB39_RS04770	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BBB39_RS04785	COG0625	glutathione transferase activity
BBB39_RS04820	COG0306	phosphate transporter
BBB39_RS04825	COG0521	Mo-molybdopterin cofactor biosynthetic process
BBB39_RS04835	COG0739	heme binding
BBB39_RS04845	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BBB39_RS04850	COG3181	Tripartite tricarboxylate transporter family receptor
BBB39_RS04860	COG0583	DNA-binding transcription factor activity
BBB39_RS04870	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BBB39_RS04875	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BBB39_RS04890	COG0405	Gamma-glutamyltransferase
BBB39_RS04905	COG1301	dicarboxylic acid transport
BBB39_RS04915	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BBB39_RS04920	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BBB39_RS04925	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BBB39_RS04930	COG0009	L-threonylcarbamoyladenylate synthase
BBB39_RS04940	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BBB39_RS04955	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BBB39_RS04965	COG1960	acyl-CoA dehydrogenase activity
BBB39_RS04970	COG1960	acyl-CoA dehydrogenase activity
BBB39_RS04985	COG1960	acyl-CoA dehydrogenase activity
BBB39_RS04990	COG0028	Belongs to the TPP enzyme family
BBB39_RS04995	COG0583	DNA-binding transcription factor activity
BBB39_RS05000	COG4974	Belongs to the 'phage' integrase family
BBB39_RS05005	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BBB39_RS05010	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BBB39_RS05020	COG1686	Belongs to the peptidase S11 family
BBB39_RS05045	COG1074	ATP-dependent DNA helicase activity
BBB39_RS05055	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BBB39_RS05060	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BBB39_RS05070	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BBB39_RS05075	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BBB39_RS05085	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BBB39_RS05090	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BBB39_RS05095	COG0505	Belongs to the CarA family
BBB39_RS05100	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BBB39_RS05110	COG1028	Short-chain dehydrogenase reductase Sdr
BBB39_RS05130	COG2233	PERMEase
BBB39_RS05135	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BBB39_RS05145	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BBB39_RS05150	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BBB39_RS05160	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BBB39_RS05170	COG0248	Ppx GppA phosphatase
BBB39_RS05175	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BBB39_RS05200	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BBB39_RS05385	COG4695	Portal protein
BBB39_RS05410	COG0582	viral genome integration into host DNA
BBB39_RS05420	COG1595	DNA-templated transcription, initiation
BBB39_RS05430	COG4774	siderophore transport
BBB39_RS05480	COG3963	phosphatidate phosphatase activity
BBB39_RS05490	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BBB39_RS05495	COG0436	Aminotransferase
BBB39_RS05500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BBB39_RS05510	COG0765	amino acid transport
BBB39_RS05515	COG1126	abc transporter atp-binding protein
BBB39_RS05525	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
BBB39_RS05530	COG2203	Gaf domain
BBB39_RS05530	COG2199	diguanylate cyclase activity
BBB39_RS05535	COG0154	amidase activity
BBB39_RS05545	COG1024	Enoyl-CoA hydratase
BBB39_RS05550	COG2186	Transcriptional regulator
BBB39_RS05555	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BBB39_RS05560	COG0154	amidase activity
BBB39_RS05565	COG2814	Major facilitator Superfamily
BBB39_RS05575	COG4774	siderophore transport
BBB39_RS05600	COG1024	Enoyl-CoA hydratase
BBB39_RS05605	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BBB39_RS05615	COG1024	Enoyl-CoA hydratase
BBB39_RS05620	COG0318	PFAM AMP-dependent synthetase and ligase
BBB39_RS05625	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BBB39_RS05640	COG0633	Ferredoxin
BBB39_RS05690	COG0243	molybdopterin cofactor binding
BBB39_RS05725	COG0598	Magnesium transport protein CorA
BBB39_RS05745	COG4191	Histidine kinase
BBB39_RS05750	COG4566	intracellular signal transduction
BBB39_RS05755	COG0129	dihydroxy-acid dehydratase activity
BBB39_RS05760	COG1012	belongs to the aldehyde dehydrogenase family
BBB39_RS05790	COG2186	Transcriptional regulator
BBB39_RS05810	COG4948	Mandelate Racemase Muconate Lactonizing
BBB39_RS05825	COG0583	DNA-binding transcription factor activity
BBB39_RS05840	COG1802	Transcriptional regulator
BBB39_RS05855	COG3246	L-lysine catabolic process to acetate
BBB39_RS05890	COG1136	(ABC) transporter
BBB39_RS05900	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BBB39_RS05925	COG3181	Tripartite tricarboxylate transporter family receptor
BBB39_RS05930	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BBB39_RS05950	COG0601	transmembrane transport
BBB39_RS05955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BBB39_RS05960	COG4172	Belongs to the ABC transporter superfamily
BBB39_RS05965	COG0747	negative chemotaxis
BBB39_RS05975	COG0583	DNA-binding transcription factor activity
BBB39_RS06010	COG3307	-O-antigen
BBB39_RS06020	COG1215	transferase activity, transferring glycosyl groups
BBB39_RS06035	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BBB39_RS06080	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
BBB39_RS06080	COG0662	Cupin 2, conserved barrel domain protein
BBB39_RS06095	COG2894	cell division
BBB39_RS06100	COG1215	transferase activity, transferring glycosyl groups
BBB39_RS06105	COG1215	transferase activity, transferring glycosyl groups
BBB39_RS06110	COG1215	transferase activity, transferring glycosyl groups
BBB39_RS06115	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BBB39_RS06120	COG0457	Tetratricopeptide repeat
BBB39_RS06145	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BBB39_RS06160	COG4608	Belongs to the ABC transporter superfamily
BBB39_RS06165	COG0444	Belongs to the ABC transporter superfamily
BBB39_RS06170	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BBB39_RS06175	COG0601	transmembrane transport
BBB39_RS06180	COG0583	DNA-binding transcription factor activity
BBB39_RS06185	COG2837	iron assimilation
BBB39_RS06205	COG0500	methyltransferase
BBB39_RS06215	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
BBB39_RS06230	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BBB39_RS06235	COG0671	phosphoesterase, PA-phosphatase related
BBB39_RS06260	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BBB39_RS06265	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BBB39_RS06270	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BBB39_RS06275	COG0649	NAD binding
BBB39_RS06280	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BBB39_RS06290	COG1034	ATP synthesis coupled electron transport
BBB39_RS06295	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BBB39_RS06300	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BBB39_RS06310	COG0713	ATP synthesis coupled electron transport
BBB39_RS06325	COG1007	ATP synthesis coupled electron transport
BBB39_RS06335	COG0560	Phosphoserine phosphatase
BBB39_RS06340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BBB39_RS06345	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BBB39_RS06350	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BBB39_RS06355	COG2207	Transcriptional regulator
BBB39_RS06360	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BBB39_RS06365	COG0450	alkyl hydroperoxide reductase
BBB39_RS06380	COG1214	PFAM Peptidase M22, glycoprotease
BBB39_RS06385	COG1573	uracil-dna glycosylase
BBB39_RS06390	COG0477	Major facilitator Superfamily
BBB39_RS06395	COG1196	nuclear chromosome segregation
BBB39_RS06405	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BBB39_RS06410	COG1126	abc transporter atp-binding protein
BBB39_RS06415	COG0765	amino acid transport
BBB39_RS06420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BBB39_RS06425	COG0477	Major facilitator Superfamily
BBB39_RS06430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BBB39_RS06440	COG2917	probably involved in intracellular septation
BBB39_RS06445	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BBB39_RS06450	COG1122	ATPase activity
BBB39_RS06455	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BBB39_RS06460	COG1268	BioY protein
BBB39_RS06485	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BBB39_RS06515	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BBB39_RS06520	COG2878	Part of a membrane complex involved in electron transport
BBB39_RS06535	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BBB39_RS06540	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BBB39_RS06545	COG0251	oxidation-reduction process
BBB39_RS06555	COG3228	Belongs to the MtfA family
BBB39_RS06560	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BBB39_RS06570	COG0133	tryptophan synthase activity
BBB39_RS06575	COG0159	tryptophan synthase activity
BBB39_RS06580	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BBB39_RS06585	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BBB39_RS06590	COG1530	ribonuclease E activity
BBB39_RS06595	COG0564	pseudouridine synthase activity
BBB39_RS06600	COG0546	phosphoglycolate phosphatase activity
BBB39_RS06605	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BBB39_RS06610	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
BBB39_RS06615	COG3023	N-Acetylmuramoyl-L-alanine amidase
BBB39_RS06625	COG0424	maF-like protein
BBB39_RS06630	COG1399	metal-binding, possibly nucleic acid-binding protein
BBB39_RS06635	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BBB39_RS06645	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BBB39_RS06650	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BBB39_RS06655	COG1028	Short-chain dehydrogenase reductase Sdr
BBB39_RS06660	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BBB39_RS06665	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BBB39_RS06690	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BBB39_RS06695	COG0481	GTPase activity
BBB39_RS06700	COG0681	Belongs to the peptidase S26 family
BBB39_RS06705	COG0571	ribonuclease III activity
BBB39_RS06710	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BBB39_RS06715	COG1381	Involved in DNA repair and RecF pathway recombination
BBB39_RS06735	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BBB39_RS06745	COG0583	DNA-binding transcription factor activity
BBB39_RS06760	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BBB39_RS06765	COG0583	DNA-binding transcription factor activity
BBB39_RS06795	COG0791	NLP P60 protein
BBB39_RS06800	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BBB39_RS06805	COG3193	protein, possibly involved in utilization of glycolate and propanediol
BBB39_RS06815	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BBB39_RS06820	COG0697	spore germination
BBB39_RS06825	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
BBB39_RS06860	COG1446	asparaginase
BBB39_RS06865	COG4172	Belongs to the ABC transporter superfamily
BBB39_RS06870	COG0747	negative chemotaxis
BBB39_RS06875	COG0601	transmembrane transport
BBB39_RS06880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BBB39_RS06900	COG0504	CTP synthase activity
BBB39_RS06910	COG0148	phosphopyruvate hydratase activity
BBB39_RS06955	COG1473	amidohydrolase
BBB39_RS06975	COG2011	ABC-type metal ion transport system permease component
BBB39_RS06985	COG0583	DNA-binding transcription factor activity
BBB39_RS07000	COG1981	membrane
BBB39_RS07020	COG0039	L-malate dehydrogenase activity
BBB39_RS07025	COG2188	Transcriptional regulator
BBB39_RS07030	COG2009	succinate dehydrogenase
BBB39_RS07035	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BBB39_RS07040	COG1053	succinate dehydrogenase
BBB39_RS07045	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BBB39_RS07050	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BBB39_RS07055	COG0372	Belongs to the citrate synthase family
BBB39_RS07105	COG3210	domain, Protein
BBB39_RS07110	COG2831	hemolysin activation secretion protein
BBB39_RS07125	COG4608	Belongs to the ABC transporter superfamily
BBB39_RS07130	COG0444	Belongs to the ABC transporter superfamily
BBB39_RS07135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BBB39_RS07140	COG0601	transmembrane transport
BBB39_RS07155	COG3842	ATPase activity
BBB39_RS07165	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BBB39_RS07170	COG1840	ABC-type Fe3 transport system, periplasmic component
BBB39_RS07175	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BBB39_RS07195	COG3128	pkhd-type hydroxylase
BBB39_RS07200	COG4774	siderophore transport
BBB39_RS07205	COG3064	Membrane
BBB39_RS07205	COG3210	domain, Protein
BBB39_RS07205	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
BBB39_RS07210	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
BBB39_RS07210	COG3210	domain, Protein
BBB39_RS07210	COG3064	Membrane
BBB39_RS07215	COG0280	phosphate acetyltransferase
BBB39_RS07215	COG0281	malic enzyme
BBB39_RS07225	COG1297	OPT oligopeptide transporter protein
BBB39_RS07230	COG0567	Dehydrogenase, E1 component
BBB39_RS07235	COG0508	dehydrogenase complex catalyzes the overall conversion of
BBB39_RS07240	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BBB39_RS07245	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BBB39_RS07250	COG1595	DNA-templated transcription, initiation
BBB39_RS07255	COG3712	iron ion homeostasis
BBB39_RS07260	COG4774	siderophore transport
BBB39_RS07290	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BBB39_RS07300	COG2183	response to ionizing radiation
BBB39_RS07305	COG1199	ATP-dependent helicase activity
BBB39_RS07320	COG0564	pseudouridine synthase activity
BBB39_RS07330	COG3243	poly(R)-hydroxyalkanoic acid synthase
BBB39_RS07335	COG1028	Short-chain dehydrogenase reductase Sdr
BBB39_RS07340	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
BBB39_RS07355	COG0672	)-iron permease
BBB39_RS07380	COG3237	CsbD-like
BBB39_RS07385	COG0189	ligase activity
BBB39_RS07385	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BBB39_RS07390	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BBB39_RS07390	COG0189	ligase activity
BBB39_RS07395	COG1132	(ABC) transporter
BBB39_RS07410	COG2833	Protein of unknown function (DUF455)
BBB39_RS07415	COG2951	lytic endotransglycosylase activity
BBB39_RS07445	COG0586	Pfam SNARE associated Golgi protein
BBB39_RS07455	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BBB39_RS07470	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BBB39_RS07475	COG2197	response regulator
BBB39_RS07480	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BBB39_RS07485	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BBB39_RS07500	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BBB39_RS07505	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BBB39_RS07510	COG1764	response to oxidative stress
BBB39_RS07515	COG2423	ornithine cyclodeaminase activity
BBB39_RS07525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BBB39_RS07530	COG0765	amino acid transport
BBB39_RS07535	COG0765	amino acid transport
BBB39_RS07540	COG1126	abc transporter atp-binding protein
BBB39_RS07545	COG0756	dUTP diphosphatase activity
BBB39_RS07565	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BBB39_RS07570	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BBB39_RS07575	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BBB39_RS07580	COG0196	riboflavin kinase activity
BBB39_RS07585	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BBB39_RS07590	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BBB39_RS07590	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BBB39_RS07605	COG0210	DNA helicase
BBB39_RS07625	COG0601	transmembrane transport
BBB39_RS07630	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BBB39_RS07635	COG0747	negative chemotaxis
BBB39_RS07640	COG0402	S-adenosylhomocysteine deaminase activity
BBB39_RS07645	COG0444	Belongs to the ABC transporter superfamily
BBB39_RS07650	COG4608	Belongs to the ABC transporter superfamily
BBB39_RS07665	COG4771	TonB-dependent receptor
BBB39_RS07680	COG0488	(ABC) transporter
BBB39_RS07685	COG2890	protein-(glutamine-N5) methyltransferase activity
BBB39_RS07690	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BBB39_RS07695	COG2171	N-acyltransferase activity
BBB39_RS07710	COG1278	Cold shock
BBB39_RS07725	COG1278	Cold shock
BBB39_RS07735	COG1278	Cold shock
BBB39_RS07745	COG0544	peptidyl-prolyl cis-trans isomerase activity
BBB39_RS07750	COG0740	serine-type endopeptidase activity
BBB39_RS07755	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BBB39_RS07760	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BBB39_RS07765	COG0583	DNA-binding transcription factor activity
BBB39_RS07770	COG2031	fatty acid transporter
BBB39_RS07780	COG2423	ornithine cyclodeaminase activity
BBB39_RS07785	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BBB39_RS07795	COG0556	nucleotide-excision repair
BBB39_RS07800	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BBB39_RS07810	COG1104	cysteine desulfurase activity
BBB39_RS07815	COG0822	iron-sulfur transferase activity
BBB39_RS07820	COG0316	Belongs to the HesB IscA family
BBB39_RS07825	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BBB39_RS07830	COG0443	Heat shock 70 kDa protein
BBB39_RS07835	COG0633	Ferredoxin
BBB39_RS07840	COG2975	iron-sulfur cluster assembly
BBB39_RS07860	COG1803	Methylglyoxal synthase
BBB39_RS07870	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BBB39_RS07875	COG1028	Short-chain dehydrogenase reductase Sdr
BBB39_RS07885	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BBB39_RS07900	COG1136	(ABC) transporter
BBB39_RS07945	COG0613	PHP domain protein
BBB39_RS07955	COG0047	phosphoribosylformylglycinamidine synthase activity
BBB39_RS07955	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BBB39_RS07975	COG3181	Tripartite tricarboxylate transporter family receptor
BBB39_RS08010	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BBB39_RS08010	COG0519	Catalyzes the synthesis of GMP from XMP
BBB39_RS08015	COG0582	viral genome integration into host DNA
BBB39_RS08075	COG0589	response to stress
BBB39_RS08080	COG0659	secondary active sulfate transmembrane transporter activity
BBB39_RS08095	COG2824	Alkylphosphonate utilization operon protein PhnA
BBB39_RS08100	COG0210	DNA helicase
BBB39_RS08125	COG0583	DNA-binding transcription factor activity
BBB39_RS08145	COG1024	Enoyl-CoA hydratase
BBB39_RS08150	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BBB39_RS08155	COG0154	amidase activity
BBB39_RS08160	COG2186	Transcriptional regulator
BBB39_RS08165	COG2271	Major facilitator Superfamily
BBB39_RS08175	COG3181	Tripartite tricarboxylate transporter family receptor
BBB39_RS08180	COG0183	Belongs to the thiolase family
BBB39_RS08205	COG1028	Short-chain dehydrogenase reductase Sdr
BBB39_RS08210	COG2030	dehydratase
BBB39_RS08215	COG1024	Enoyl-CoA hydratase
BBB39_RS08230	COG0471	metal ion transport
BBB39_RS08230	COG3273	potassium ion transport
BBB39_RS08235	COG1309	transcriptional regulator
BBB39_RS08250	COG1028	Short-chain dehydrogenase reductase Sdr
BBB39_RS08255	COG1960	acyl-CoA dehydrogenase activity
BBB39_RS08260	COG1960	acyl-CoA dehydrogenase activity
BBB39_RS08265	COG1024	Enoyl-CoA hydratase
BBB39_RS08275	COG1024	Enoyl-CoA hydratase
BBB39_RS08290	COG0583	DNA-binding transcription factor activity
BBB39_RS08320	COG0488	(ABC) transporter
BBB39_RS08335	COG1024	Enoyl-CoA hydratase
BBB39_RS08350	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BBB39_RS08355	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BBB39_RS08390	COG3181	Tripartite tricarboxylate transporter family receptor
BBB39_RS08395	COG0596	Alpha beta hydrolase
BBB39_RS08405	COG1024	Enoyl-CoA hydratase
BBB39_RS08415	COG2207	Transcriptional regulator
BBB39_RS08420	COG4771	TonB-dependent receptor
BBB39_RS08435	COG2814	Major facilitator Superfamily
BBB39_RS08445	COG0583	DNA-binding transcription factor activity
BBB39_RS08450	COG3181	Tripartite tricarboxylate transporter family receptor
BBB39_RS08475	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BBB39_RS08480	COG0688	phosphatidylethanolamine metabolic process
BBB39_RS08485	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BBB39_RS08490	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BBB39_RS08510	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BBB39_RS08515	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BBB39_RS08520	COG2207	Transcriptional regulator
BBB39_RS08520	COG1917	Cupin 2, conserved barrel domain protein
BBB39_RS08535	COG1846	Transcriptional regulator
BBB39_RS08540	COG2365	Tyrosine phosphatase family
BBB39_RS08565	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BBB39_RS08590	COG0583	DNA-binding transcription factor activity
BBB39_RS08595	COG3181	Tripartite tricarboxylate transporter family receptor
BBB39_RS08600	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BBB39_RS08610	COG3135	benzoate transporter
BBB39_RS08625	COG1960	acyl-CoA dehydrogenase activity
BBB39_RS08645	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BBB39_RS08655	COG0583	DNA-binding transcription factor activity
BBB39_RS08665	COG0351	phosphomethylpyrimidine kinase
BBB39_RS08670	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BBB39_RS08690	COG0456	acetyltransferase
BBB39_RS08710	COG0583	DNA-binding transcription factor activity
BBB39_RS08720	COG2814	Major facilitator Superfamily
BBB39_RS08730	COG4585	Histidine kinase
BBB39_RS08765	COG0653	protein targeting
BBB39_RS08770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BBB39_RS08785	COG2207	Transcriptional regulator
BBB39_RS08790	COG2807	transmembrane transport
BBB39_RS08815	COG2814	Major facilitator Superfamily
BBB39_RS08820	COG0583	DNA-binding transcription factor activity
BBB39_RS08830	COG1522	sequence-specific DNA binding
BBB39_RS08870	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BBB39_RS08900	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
BBB39_RS08905	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BBB39_RS08910	COG0390	transport system, permease component
BBB39_RS08920	COG0583	DNA-binding transcription factor activity
BBB39_RS08930	COG0477	Major facilitator Superfamily
BBB39_RS08935	COG0500	methyltransferase
BBB39_RS08940	COG1418	mRNA catabolic process
BBB39_RS08955	COG0424	maF-like protein
BBB39_RS08960	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BBB39_RS08965	COG0799	negative regulation of ribosome biogenesis
BBB39_RS08970	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BBB39_RS08980	COG0151	Belongs to the GarS family
BBB39_RS08985	COG0217	transcriptional regulatory protein
BBB39_RS08990	COG0433	COG0433 Predicted ATPase
BBB39_RS08995	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BBB39_RS09005	COG1012	belongs to the aldehyde dehydrogenase family
BBB39_RS09030	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BBB39_RS09040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BBB39_RS09045	COG0601	transmembrane transport
BBB39_RS09050	COG0747	negative chemotaxis
BBB39_RS09065	COG0473	3-isopropylmalate dehydrogenase activity
BBB39_RS09070	COG1335	isochorismatase
BBB39_RS09080	COG0583	DNA-binding transcription factor activity
BBB39_RS09090	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BBB39_RS09095	COG1335	isochorismatase
BBB39_RS09115	COG2271	Major facilitator Superfamily
BBB39_RS09420	COG0501	Belongs to the peptidase M48B family
BBB39_RS09430	COG0789	Transcriptional regulator
BBB39_RS09455	COG4232	protein-disulfide reductase activity
BBB39_RS09465	COG0730	response to heat
BBB39_RS09475	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BBB39_RS09480	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BBB39_RS09485	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BBB39_RS09505	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BBB39_RS09520	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BBB39_RS09520	COG0678	peroxiredoxin activity
BBB39_RS09530	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BBB39_RS09535	COG0584	glycerophosphoryl diester phosphodiesterase
BBB39_RS09540	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BBB39_RS09550	COG4181	ATPase activity
BBB39_RS09560	COG3210	domain, Protein
BBB39_RS09560	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
BBB39_RS09560	COG3210	domain, Protein
BBB39_RS09560	COG3064	Membrane
BBB39_RS09560	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
BBB39_RS09560	COG3064	Membrane
BBB39_RS09565	COG3121	Chaperone
BBB39_RS09570	COG3188	usher protein
BBB39_RS09585	COG2831	hemolysin activation secretion protein
BBB39_RS09615	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BBB39_RS09620	COG1758	RNA polymerase activity
BBB39_RS09625	COG0194	GDP metabolic process
BBB39_RS09630	COG1028	Short-chain dehydrogenase reductase Sdr
BBB39_RS09635	COG0791	NLP P60 protein
BBB39_RS09645	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BBB39_RS09650	COG1561	YicC-like family, N-terminal region
BBB39_RS09655	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BBB39_RS09660	COG2079	MmgE PrpD family protein
BBB39_RS09665	COG1960	acyl-CoA dehydrogenase activity
BBB39_RS09675	COG0840	transmembrane signaling receptor activity
BBB39_RS09680	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BBB39_RS09685	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BBB39_RS09690	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BBB39_RS09695	COG0174	glutamine synthetase
BBB39_RS09700	COG3852	Histidine kinase
BBB39_RS09705	COG2204	response regulator
BBB39_RS09735	COG0583	DNA-binding transcription factor activity
BBB39_RS09740	COG1741	Belongs to the pirin family
BBB39_RS09745	COG1741	Belongs to the pirin family
BBB39_RS09755	COG4149	molybdate abc transporter
BBB39_RS09760	COG1840	ABC-type Fe3 transport system, periplasmic component
BBB39_RS09775	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BBB39_RS09780	COG0583	DNA-binding transcription factor activity
BBB39_RS09785	COG0783	Belongs to the Dps family
BBB39_RS09800	COG3842	ATPase activity
BBB39_RS09810	COG1175	transmembrane transport
BBB39_RS09815	COG1653	transport
BBB39_RS09825	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BBB39_RS09835	COG0559	Belongs to the binding-protein-dependent transport system permease family
BBB39_RS09855	COG1794	racemase activity, acting on amino acids and derivatives
BBB39_RS09860	COG0625	glutathione transferase activity
BBB39_RS09865	COG0697	spore germination
BBB39_RS09870	COG2363	Small membrane protein
BBB39_RS09885	COG1464	Belongs to the NlpA lipoprotein family
BBB39_RS09895	COG0688	phosphatidylethanolamine metabolic process
BBB39_RS09905	COG0028	Belongs to the TPP enzyme family
BBB39_RS09910	COG2186	Transcriptional regulator
BBB39_RS09915	COG3189	MarR family transcriptional regulator
BBB39_RS09930	COG2197	response regulator
BBB39_RS09935	COG1716	ATPase activity
BBB39_RS09935	COG5001	Diguanylate cyclase
BBB39_RS09945	COG1253	flavin adenine dinucleotide binding
BBB39_RS09960	COG2200	EAL domain
BBB39_RS09970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BBB39_RS09975	COG0765	amino acid transport
BBB39_RS09980	COG1126	abc transporter atp-binding protein
BBB39_RS10020	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BBB39_RS10035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BBB39_RS10055	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BBB39_RS10060	COG0747	negative chemotaxis
BBB39_RS10070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BBB39_RS10075	COG4172	Belongs to the ABC transporter superfamily
BBB39_RS10080	COG0640	Transcriptional regulator
BBB39_RS10085	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BBB39_RS10100	COG3181	Tripartite tricarboxylate transporter family receptor
BBB39_RS10105	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BBB39_RS10110	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BBB39_RS10115	COG1802	Transcriptional regulator
BBB39_RS10120	COG1960	acyl-CoA dehydrogenase activity
BBB39_RS10135	COG1250	3-hydroxyacyl-CoA dehydrogenase
BBB39_RS10135	COG1024	Enoyl-CoA hydratase
BBB39_RS10140	COG0183	Belongs to the thiolase family
BBB39_RS10145	COG1028	Short-chain dehydrogenase reductase Sdr
BBB39_RS10155	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BBB39_RS10170	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BBB39_RS10175	COG1024	Enoyl-CoA hydratase
BBB39_RS10180	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BBB39_RS10185	COG1024	Enoyl-CoA hydratase
BBB39_RS10190	COG1464	Belongs to the NlpA lipoprotein family
BBB39_RS10215	COG0251	oxidation-reduction process
BBB39_RS10235	COG1113	amino acid transport
BBB39_RS10240	COG2986	histidine ammonia-lyase
BBB39_RS10245	COG1234	tRNA 3'-trailer cleavage
BBB39_RS10260	COG4585	Histidine kinase
BBB39_RS10265	COG1024	Enoyl-CoA hydratase
BBB39_RS10270	COG1024	Enoyl-CoA hydratase
BBB39_RS10275	COG0318	PFAM AMP-dependent synthetase and ligase
BBB39_RS10280	COG1960	acyl-CoA dehydrogenase activity
BBB39_RS10290	COG4771	TonB-dependent receptor
BBB39_RS10295	COG0583	DNA-binding transcription factor activity
BBB39_RS10300	COG0154	amidase activity
BBB39_RS10310	COG1522	sequence-specific DNA binding
BBB39_RS10320	COG0251	oxidation-reduction process
BBB39_RS10325	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BBB39_RS10355	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BBB39_RS10365	COG1116	anion transmembrane transporter activity
BBB39_RS10370	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BBB39_RS10380	COG0604	alcohol dehydrogenase
BBB39_RS10390	COG0318	PFAM AMP-dependent synthetase and ligase
BBB39_RS10405	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BBB39_RS10410	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BBB39_RS10415	COG2900	Belongs to the SlyX family
BBB39_RS10420	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BBB39_RS10445	COG1960	acyl-CoA dehydrogenase activity
BBB39_RS10450	COG1960	acyl-CoA dehydrogenase activity
BBB39_RS10465	COG1024	Enoyl-CoA hydratase
BBB39_RS10480	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BBB39_RS10480	COG0519	Catalyzes the synthesis of GMP from XMP
BBB39_RS10505	COG3608	succinylglutamate desuccinylase aspartoacylase
BBB39_RS10525	COG3258	Cytochrome c
BBB39_RS10540	COG2733	membrane
BBB39_RS10580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BBB39_RS10585	COG1129	ABC transporter
BBB39_RS10585	COG0842	Transport permease protein
BBB39_RS10590	COG0842	Transport permease protein
BBB39_RS10600	COG1028	Short-chain dehydrogenase reductase Sdr
BBB39_RS10620	COG1393	Belongs to the ArsC family
BBB39_RS10625	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BBB39_RS10630	COG0415	Belongs to the DNA photolyase family
BBB39_RS10650	COG0386	Belongs to the glutathione peroxidase family
BBB39_RS10665	COG0095	Lipoate-protein ligase
BBB39_RS10675	COG0740	serine-type endopeptidase activity
BBB39_RS10690	COG0625	glutathione transferase activity
BBB39_RS10700	COG0024	Methionine aminopeptidase
BBB39_RS10710	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BBB39_RS10720	COG0084	hydrolase, TatD family'
BBB39_RS10725	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BBB39_RS10730	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BBB39_RS10735	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BBB39_RS10740	COG0354	folic acid binding
BBB39_RS10755	COG1250	3-hydroxyacyl-CoA dehydrogenase
BBB39_RS10755	COG1024	Enoyl-CoA hydratase
BBB39_RS10760	COG1960	acyl-CoA dehydrogenase activity
BBB39_RS10765	COG2914	Belongs to the UPF0125 (RnfH) family
BBB39_RS10770	COG2867	negative regulation of translational initiation
BBB39_RS10775	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BBB39_RS10795	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BBB39_RS10800	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BBB39_RS10805	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BBB39_RS10810	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BBB39_RS10820	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BBB39_RS10825	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BBB39_RS10830	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
BBB39_RS10835	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BBB39_RS10840	COG0750	zinc metalloprotease
BBB39_RS10845	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BBB39_RS10850	COG0575	Belongs to the CDS family
BBB39_RS10855	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BBB39_RS10860	COG0233	cytoplasmic translational termination
BBB39_RS10865	COG0528	UMP kinase activity
BBB39_RS10870	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BBB39_RS10875	COG0052	Belongs to the universal ribosomal protein uS2 family
BBB39_RS10880	COG0024	Methionine aminopeptidase
BBB39_RS10885	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BBB39_RS10890	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BBB39_RS10900	COG1286	toxin biosynthetic process
BBB39_RS10910	COG0285	dihydrofolate synthase activity
BBB39_RS10950	COG1677	Flagellar hook-basal body complex protein FliE
BBB39_RS10960	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BBB39_RS10965	COG1317	bacterial-type flagellum organization
BBB39_RS10975	COG2882	bacterial-type flagellum organization
BBB39_RS10985	COG1580	Controls the rotational direction of flagella during chemotaxis
BBB39_RS11010	COG1987	bacterial-type flagellum assembly
BBB39_RS11020	COG0840	transmembrane signaling receptor activity
BBB39_RS11025	COG0840	transmembrane signaling receptor activity
BBB39_RS11035	COG0840	transmembrane signaling receptor activity
BBB39_RS11045	COG1256	bacterial-type flagellum assembly
BBB39_RS11055	COG1706	bacterial-type flagellum-dependent cell motility
BBB39_RS11070	COG4787	bacterial-type flagellum-dependent cell motility
BBB39_RS11075	COG1749	Flagellar hook protein flgE
BBB39_RS11085	COG1558	bacterial-type flagellum-dependent cell motility
BBB39_RS11125	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
BBB39_RS11130	COG0745	RESPONSE REGULATOR receiver
BBB39_RS11135	COG2201	protein-glutamate methylesterase activity
BBB39_RS11140	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BBB39_RS11145	COG0840	transmembrane signaling receptor activity
BBB39_RS11160	COG0745	RESPONSE REGULATOR receiver
BBB39_RS11165	COG1360	Flagellar Motor Protein
BBB39_RS11185	COG1191	sigma factor activity
BBB39_RS11195	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BBB39_RS11195	COG4797	methyltransferase
BBB39_RS11200	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BBB39_RS11205	COG0508	dehydrogenase complex catalyzes the overall conversion of
BBB39_RS11210	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BBB39_RS11220	COG4566	intracellular signal transduction
BBB39_RS11225	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BBB39_RS11270	COG1187	pseudouridine synthase activity
BBB39_RS11275	COG3161	chorismate lyase activity
BBB39_RS11290	COG4172	Belongs to the ABC transporter superfamily
BBB39_RS11295	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BBB39_RS11300	COG0601	transmembrane transport
BBB39_RS11305	COG0747	negative chemotaxis
BBB39_RS11315	COG0583	DNA-binding transcription factor activity
BBB39_RS11345	COG0668	transmembrane transport
BBB39_RS11350	COG0165	Argininosuccinate lyase
BBB39_RS11355	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BBB39_RS11360	COG2252	PERMEase
BBB39_RS11365	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BBB39_RS11370	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BBB39_RS11400	COG0488	(ABC) transporter
BBB39_RS11405	COG1619	proteins homologs of microcin C7 resistance protein MccF
BBB39_RS11410	COG0590	tRNA wobble adenosine to inosine editing
BBB39_RS11430	COG2212	antiporter activity
BBB39_RS11435	COG1863	multisubunit Na H antiporter MnhE subunit
BBB39_RS11440	COG0651	ATP synthesis coupled electron transport
BBB39_RS11445	COG1006	Multisubunit Na H antiporter MnhC subunit
BBB39_RS11450	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BBB39_RS11450	COG2111	Na H antiporter
BBB39_RS11470	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BBB39_RS11500	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BBB39_RS11530	COG0477	Major facilitator Superfamily
BBB39_RS11540	COG1802	Transcriptional regulator
BBB39_RS11550	COG0602	queuosine metabolic process
BBB39_RS11555	COG0720	synthase
BBB39_RS11565	COG2814	Major facilitator Superfamily
BBB39_RS11580	COG1289	transmembrane transporter activity
BBB39_RS11590	COG1566	PFAM secretion protein HlyD family protein
BBB39_RS11615	COG0587	DNA-directed DNA polymerase activity
BBB39_RS11620	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BBB39_RS11640	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BBB39_RS11665	COG0656	L-ascorbic acid biosynthetic process
BBB39_RS11710	COG1522	sequence-specific DNA binding
BBB39_RS11720	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BBB39_RS11745	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BBB39_RS11745	COG2010	Cytochrome c
BBB39_RS11785	COG0384	phenazine biosynthesis protein PhzF
BBB39_RS11830	COG0776	regulation of translation
BBB39_RS11835	COG0072	phenylalanine-tRNA ligase activity
BBB39_RS11835	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BBB39_RS11840	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BBB39_RS11845	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BBB39_RS11850	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BBB39_RS11860	COG3119	arylsulfatase activity
BBB39_RS11875	COG0110	maltose O-acetyltransferase activity
BBB39_RS11905	COG0004	ammonium transporteR
BBB39_RS11915	COG3008	intermembrane lipid transfer
BBB39_RS11920	COG2995	paraquat-inducible protein a
BBB39_RS11925	COG0542	response to heat
BBB39_RS11930	COG4953	penicillin-binding protein 1C
BBB39_RS11940	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BBB39_RS11945	COG1278	Cold shock
BBB39_RS11955	COG0183	Belongs to the thiolase family
BBB39_RS11960	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BBB39_RS11965	COG1570	exodeoxyribonuclease VII activity
BBB39_RS11970	COG0811	peptide transport
BBB39_RS11975	COG0848	biopolymer transport protein
BBB39_RS11980	COG1663	tetraacyldisaccharide 4'-kinase activity
BBB39_RS11985	COG2835	tetraacyldisaccharide 4'-kinase activity
BBB39_RS11990	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BBB39_RS11995	COG0563	adenylate kinase activity
BBB39_RS12005	COG0728	peptidoglycan biosynthetic process
BBB39_RS12015	COG0268	Binds directly to 16S ribosomal RNA
BBB39_RS12035	COG2186	Transcriptional regulator
BBB39_RS12050	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BBB39_RS12060	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BBB39_RS12075	COG3971	2-oxopent-4-enoate hydratase activity
BBB39_RS12080	COG3158	transport of potassium into the cell
BBB39_RS12085	COG0642	Histidine kinase
BBB39_RS12115	COG0776	regulation of translation
BBB39_RS12125	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BBB39_RS12130	COG0557	exoribonuclease II activity
BBB39_RS12165	COG0069	glutamate synthase activity
BBB39_RS12190	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BBB39_RS12220	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BBB39_RS12225	COG0028	Belongs to the TPP enzyme family
BBB39_RS12235	COG3706	GGDEF domain
BBB39_RS12240	COG3706	GGDEF domain
BBB39_RS12250	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BBB39_RS12260	COG0628	permease
BBB39_RS12275	COG3909	cytochrome
BBB39_RS12285	COG0625	glutathione transferase activity
BBB39_RS12290	COG0730	response to heat
BBB39_RS12295	COG0482	sulfurtransferase activity
BBB39_RS12300	COG0583	DNA-binding transcription factor activity
BBB39_RS12330	COG0247	lactate metabolic process
BBB39_RS12335	COG0277	FAD linked oxidase domain protein
BBB39_RS12340	COG0277	FAD linked oxidase domain protein
BBB39_RS12345	COG0277	FAD linked oxidase domain protein
BBB39_RS12350	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BBB39_RS12355	COG0312	modulator of DNA gyrase
BBB39_RS12370	COG0308	aminopeptidase N
BBB39_RS12375	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BBB39_RS12395	COG0436	Aminotransferase
BBB39_RS12400	COG3737	Protein of unknown function (DUF498/DUF598)
BBB39_RS12405	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BBB39_RS12410	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BBB39_RS12415	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BBB39_RS12425	COG0305	Participates in initiation and elongation during chromosome replication
BBB39_RS12435	COG0359	binds to the 23S rRNA
BBB39_RS12440	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BBB39_RS12445	COG2965	DNA replication, synthesis of RNA primer
BBB39_RS12450	COG0360	Binds together with S18 to 16S ribosomal RNA
BBB39_RS12455	COG3739	integral membrane protein
BBB39_RS12460	COG1469	GTP cyclohydrolase I activity
BBB39_RS12470	COG0142	geranyltranstransferase activity
BBB39_RS12475	COG1722	exodeoxyribonuclease VII activity
BBB39_RS12485	COG3181	Tripartite tricarboxylate transporter family receptor
BBB39_RS12515	COG0501	Belongs to the peptidase M48B family
BBB39_RS12545	COG1566	PFAM secretion protein HlyD family protein
BBB39_RS12550	COG2814	Major facilitator Superfamily
BBB39_RS12580	COG1530	ribonuclease E activity
BBB39_RS12650	COG1132	(ABC) transporter
BBB39_RS12675	COG0297	glycogen (starch) synthase activity
BBB39_RS12690	COG0463	Glycosyl transferase, family 2
BBB39_RS12695	COG0726	polysaccharide deacetylase
BBB39_RS12700	COG0438	transferase activity, transferring glycosyl groups
BBB39_RS12715	COG1643	Atp-dependent helicase
BBB39_RS12720	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BBB39_RS12720	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BBB39_RS12725	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
BBB39_RS12730	COG0704	Plays a role in the regulation of phosphate uptake
BBB39_RS12735	COG1960	acyl-CoA dehydrogenase activity
BBB39_RS12740	COG1322	Protein conserved in bacteria
BBB39_RS12750	COG2094	Belongs to the DNA glycosylase MPG family
BBB39_RS12755	COG1393	Belongs to the ArsC family
BBB39_RS12760	COG1177	transmembrane transport
BBB39_RS12765	COG1176	ABC-type spermidine putrescine transport system, permease component I
BBB39_RS12770	COG3842	ATPase activity
BBB39_RS12780	COG3642	lipopolysaccharide core region biosynthetic process
BBB39_RS12785	COG0583	DNA-binding transcription factor activity
BBB39_RS12790	COG0133	tryptophan synthase activity
BBB39_RS12795	COG0159	tryptophan synthase activity
BBB39_RS12805	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BBB39_RS12810	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BBB39_RS12820	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BBB39_RS12820	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BBB39_RS12840	COG2050	protein possibly involved in aromatic compounds catabolism
BBB39_RS12845	COG1024	Enoyl-CoA hydratase
BBB39_RS12855	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BBB39_RS12860	COG2151	metal-sulfur cluster biosynthetic enzyme
BBB39_RS12865	COG3396	Phenylacetate-CoA oxygenase
BBB39_RS12870	COG3460	Phenylacetate-CoA oxygenase
BBB39_RS12875	COG3396	Phenylacetate-CoA oxygenase
BBB39_RS12880	COG3327	negative regulation of DNA-templated transcription, initiation
BBB39_RS12890	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BBB39_RS12895	COG0501	Belongs to the peptidase M48B family
BBB39_RS12900	COG1162	GTPase activity
BBB39_RS12905	COG3622	Belongs to the hyi family
BBB39_RS12915	COG0335	large ribosomal subunit rRNA binding
BBB39_RS12945	COG0450	alkyl hydroperoxide reductase
BBB39_RS12950	COG1960	acyl-CoA dehydrogenase activity
BBB39_RS12955	COG2985	domain, Protein
BBB39_RS12970	COG0123	including yeast histone deacetylase and acetoin utilization protein
BBB39_RS12975	COG2951	lytic endotransglycosylase activity
BBB39_RS12990	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BBB39_RS12995	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BBB39_RS13000	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BBB39_RS13020	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BBB39_RS13025	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BBB39_RS13030	COG0287	Prephenate dehydrogenase
BBB39_RS13035	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BBB39_RS13045	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BBB39_RS13060	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BBB39_RS13225	COG5410	chromosome segregation
BBB39_RS13265	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BBB39_RS13275	COG3756	Protein conserved in bacteria
BBB39_RS13315	COG1192	Involved in chromosome partitioning
BBB39_RS13365	COG0629	single-stranded DNA binding
BBB39_RS13410	COG0582	viral genome integration into host DNA
BBB39_RS13440	COG1024	Enoyl-CoA hydratase
BBB39_RS13445	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BBB39_RS13450	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BBB39_RS13455	COG0604	alcohol dehydrogenase
BBB39_RS13485	COG0583	DNA-binding transcription factor activity
BBB39_RS13490	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BBB39_RS13490	COG2755	lipolytic protein G-D-S-L family
BBB39_RS13495	COG2755	lipolytic protein G-D-S-L family
BBB39_RS13495	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BBB39_RS13500	COG3706	GGDEF domain
BBB39_RS13510	COG0135	phosphoribosylanthranilate isomerase activity
BBB39_RS13515	COG0101	tRNA pseudouridine synthase activity
BBB39_RS13525	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BBB39_RS13530	COG0473	3-isopropylmalate dehydrogenase activity
BBB39_RS13535	COG0066	3-isopropylmalate dehydratase activity
BBB39_RS13555	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BBB39_RS13565	COG2205	protein histidine kinase activity
BBB39_RS13575	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BBB39_RS13580	COG1295	ribonuclease BN
BBB39_RS13590	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BBB39_RS13625	COG4964	Belongs to the GSP D family
BBB39_RS13660	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BBB39_RS13665	COG1960	acyl-CoA dehydrogenase activity
BBB39_RS13700	COG0181	hydroxymethylbilane synthase activity
BBB39_RS13705	COG0861	Integral membrane protein TerC family
BBB39_RS13710	COG0861	Integral membrane protein TerC family
BBB39_RS13715	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BBB39_RS13720	COG0045	succinate-CoA ligase (ADP-forming) activity
BBB39_RS13730	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BBB39_RS13740	COG2137	regulation of response to DNA damage stimulus
BBB39_RS13745	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BBB39_RS13765	COG2974	May be involved in recombination
BBB39_RS13770	COG0540	Belongs to the ATCase OTCase family
BBB39_RS13800	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BBB39_RS13820	COG0330	HflC and HflK could
BBB39_RS13825	COG0784	Response regulator, receiver
BBB39_RS13825	COG3437	response regulator, receiver
BBB39_RS13860	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BBB39_RS13870	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BBB39_RS13880	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BBB39_RS13885	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BBB39_RS13890	COG0330	HflC and HflK could
BBB39_RS13895	COG0330	HflC and HflK could
BBB39_RS13900	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BBB39_RS13905	COG1923	regulation of RNA biosynthetic process
BBB39_RS13910	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BBB39_RS13915	COG1160	GTP binding
BBB39_RS13920	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BBB39_RS13925	COG2976	Protein conserved in bacteria
BBB39_RS13930	COG0124	histidyl-tRNA synthetase
BBB39_RS13945	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BBB39_RS13950	COG0105	UTP biosynthetic process
BBB39_RS13955	COG0525	valine-tRNA ligase activity
BBB39_RS13960	COG0336	Belongs to the RNA methyltransferase TrmD family
BBB39_RS13965	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BBB39_RS13970	COG0228	four-way junction DNA binding
BBB39_RS13975	COG0425	Belongs to the sulfur carrier protein TusA family
BBB39_RS13980	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BBB39_RS14030	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BBB39_RS14035	COG0543	2 iron, 2 sulfur cluster binding
BBB39_RS14035	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BBB39_RS14040	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BBB39_RS14045	COG2076	Multidrug Resistance protein
BBB39_RS14050	COG3217	Mosc domain protein beta barrel domain protein
BBB39_RS14050	COG0633	Ferredoxin
BBB39_RS14055	COG5285	phytanoyl-CoA dioxygenase
BBB39_RS14060	COG0662	Cupin 2, conserved barrel domain protein
BBB39_RS14080	COG2311	Membrane
BBB39_RS14105	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BBB39_RS14125	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BBB39_RS14130	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BBB39_RS14135	COG1760	l-serine dehydratase
BBB39_RS14140	COG1283	sodium-dependent phosphate transmembrane transporter activity
BBB39_RS14145	COG0412	Dienelactone hydrolase
BBB39_RS14155	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BBB39_RS14155	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BBB39_RS14170	COG1217	gtp-binding protein TYPA
BBB39_RS14175	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BBB39_RS14180	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BBB39_RS14185	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BBB39_RS14190	COG2251	uridine kinase activity
BBB39_RS14190	COG0195	Participates in both transcription termination and antitermination
BBB39_RS14195	COG0779	Required for maturation of 30S ribosomal subunits
BBB39_RS14200	COG1187	pseudouridine synthase activity
BBB39_RS14205	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BBB39_RS14215	COG0523	cobalamin synthesis protein
BBB39_RS14230	COG0625	glutathione transferase activity
BBB39_RS14235	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BBB39_RS14245	COG2003	Belongs to the UPF0758 family
BBB39_RS14250	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BBB39_RS14255	COG3483	tryptophan 2,3-dioxygenase activity
BBB39_RS14260	COG0254	rRNA binding
BBB39_RS14310	COG1028	Short-chain dehydrogenase reductase Sdr
BBB39_RS14315	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BBB39_RS14325	COG1562	ergosterol biosynthetic process
BBB39_RS14330	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
BBB39_RS14330	COG0493	'glutamate synthase
BBB39_RS14335	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BBB39_RS14360	COG1477	protein flavinylation
BBB39_RS14375	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BBB39_RS14380	COG0583	DNA-binding transcription factor activity
BBB39_RS14385	COG0542	response to heat
BBB39_RS14390	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BBB39_RS14400	COG0494	nUDIX hydrolase
BBB39_RS14410	COG0583	DNA-binding transcription factor activity
BBB39_RS14415	COG3530	Putative quorum-sensing-regulated virulence factor
BBB39_RS14445	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
BBB39_RS14455	COG0628	permease
BBB39_RS14460	COG0842	Transport permease protein
BBB39_RS14465	COG1131	(ABC) transporter
BBB39_RS14475	COG0156	8-amino-7-oxononanoate synthase activity
BBB39_RS14485	COG4106	trans-aconitate 2-methyltransferase activity
BBB39_RS14485	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BBB39_RS14490	COG5006	permease, DMT superfamily
BBB39_RS14495	COG1522	sequence-specific DNA binding
BBB39_RS14510	COG0318	PFAM AMP-dependent synthetase and ligase
BBB39_RS14515	COG1028	Short-chain dehydrogenase reductase Sdr
BBB39_RS14520	COG2224	Isocitrate lyase
BBB39_RS14525	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BBB39_RS14525	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BBB39_RS14535	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BBB39_RS14545	COG1472	Belongs to the glycosyl hydrolase 3 family
BBB39_RS14550	COG0736	holo-[acyl-carrier-protein] synthase activity
BBB39_RS14555	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BBB39_RS14565	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BBB39_RS14570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BBB39_RS14575	COG0745	RESPONSE REGULATOR receiver
BBB39_RS14595	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BBB39_RS14600	COG4149	molybdate abc transporter
BBB39_RS14605	COG0725	ABC transporter, periplasmic molybdate-binding protein
BBB39_RS14610	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BBB39_RS14615	COG4120	Belongs to the binding-protein-dependent transport system permease family
BBB39_RS14635	COG0318	PFAM AMP-dependent synthetase and ligase
BBB39_RS14640	COG1024	Enoyl-CoA hydratase
BBB39_RS14650	COG1802	Transcriptional regulator
BBB39_RS14665	COG0183	Belongs to the thiolase family
BBB39_RS14670	COG1960	acyl-CoA dehydrogenase activity
BBB39_RS14705	COG3448	diguanylate cyclase activity
BBB39_RS14705	COG4175	Glycine betaine
BBB39_RS14710	COG4176	ABC-type proline glycine betaine transport system permease component
BBB39_RS14720	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BBB39_RS14725	COG2814	Major facilitator Superfamily
BBB39_RS14730	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BBB39_RS14735	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BBB39_RS14755	COG1846	Transcriptional regulator
BBB39_RS14760	COG2814	Major facilitator Superfamily
BBB39_RS14765	COG0495	leucyl-tRNA aminoacylation
BBB39_RS14780	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BBB39_RS14815	COG0579	oxidoreductase
BBB39_RS14845	COG0427	acetyl-CoA hydrolase
BBB39_RS14850	COG0583	DNA-binding transcription factor activity
BBB39_RS14855	COG3264	Mechanosensitive ion channel
BBB39_RS14855	COG1511	domain protein
BBB39_RS14885	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BBB39_RS14890	COG3384	dioxygenase
BBB39_RS14905	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BBB39_RS14925	COG4172	Belongs to the ABC transporter superfamily
BBB39_RS14930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BBB39_RS14940	COG0747	negative chemotaxis
BBB39_RS14950	COG0598	Magnesium transport protein CorA
BBB39_RS14955	COG0210	DNA helicase
BBB39_RS14970	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BBB39_RS14990	COG0483	inositol monophosphate 1-phosphatase activity
BBB39_RS14995	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BBB39_RS15005	COG1045	serine acetyltransferase
BBB39_RS15010	COG0183	Belongs to the thiolase family
BBB39_RS15015	COG1250	3-hydroxyacyl-CoA dehydrogenase
BBB39_RS15015	COG1024	Enoyl-CoA hydratase
BBB39_RS15020	COG1024	Enoyl-CoA hydratase
BBB39_RS15020	COG1250	3-hydroxyacyl-CoA dehydrogenase
BBB39_RS15025	COG0183	Belongs to the thiolase family
BBB39_RS15030	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BBB39_RS15040	COG1902	pentaerythritol trinitrate reductase activity
BBB39_RS15045	COG0625	glutathione transferase activity
BBB39_RS15065	COG1132	(ABC) transporter
BBB39_RS15095	COG0037	tRNA processing
BBB39_RS15100	COG0825	malonyl-CoA metabolic process
BBB39_RS15110	COG0215	cysteine-tRNA ligase activity
BBB39_RS15120	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BBB39_RS15130	COG1968	undecaprenyl-diphosphatase activity
BBB39_RS15135	COG1253	flavin adenine dinucleotide binding
BBB39_RS15140	COG0483	inositol monophosphate 1-phosphatase activity
BBB39_RS15160	COG0668	transmembrane transport
BBB39_RS15205	COG4771	TonB-dependent receptor
BBB39_RS15215	COG0745	RESPONSE REGULATOR receiver
BBB39_RS15220	COG2169	Transcriptional regulator
BBB39_RS15230	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BBB39_RS15235	COG2850	peptidyl-arginine hydroxylation
BBB39_RS15250	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BBB39_RS15255	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BBB39_RS15260	COG1994	Peptidase M50
BBB39_RS15265	COG0009	L-threonylcarbamoyladenylate synthase
BBB39_RS15270	COG2321	neutral zinc metallopeptidase
BBB39_RS15290	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BBB39_RS15295	COG1475	DNA binding
BBB39_RS15300	COG3969	phosphoadenosine phosphosulfate
BBB39_RS15305	COG1238	metal cluster binding
BBB39_RS15320	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BBB39_RS15350	COG1522	sequence-specific DNA binding
BBB39_RS15360	COG3181	Tripartite tricarboxylate transporter family receptor
BBB39_RS15365	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
BBB39_RS15380	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BBB39_RS15385	COG3278	Belongs to the heme-copper respiratory oxidase family
BBB39_RS15395	COG2863	cytochrome
BBB39_RS15400	COG3258	Cytochrome c
BBB39_RS15405	COG2217	Heavy metal translocating P-type atpase
BBB39_RS15630	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BBB39_RS15635	COG3723	Recombinational DNA repair protein, rece pathway
BBB39_RS15700	COG0583	DNA-binding transcription factor activity
BBB39_RS15705	COG1028	Short-chain dehydrogenase reductase Sdr
BBB39_RS15715	COG0179	Fumarylacetoacetate (FAA) hydrolase
BBB39_RS15730	COG1464	Belongs to the NlpA lipoprotein family
BBB39_RS15755	COG3181	Tripartite tricarboxylate transporter family receptor
BBB39_RS15760	COG4604	ABC transporter, ATP-binding protein
BBB39_RS15765	COG4605	iron ion homeostasis
BBB39_RS15770	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BBB39_RS15775	COG4607	ABC-type enterochelin transport system periplasmic component
BBB39_RS15785	COG0149	triose-phosphate isomerase activity
BBB39_RS15790	COG1028	Short-chain dehydrogenase reductase Sdr
BBB39_RS15790	COG3321	synthase
BBB39_RS15790	COG0604	alcohol dehydrogenase
BBB39_RS15810	COG4774	siderophore transport
BBB39_RS15830	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BBB39_RS15840	COG1185	polyribonucleotide nucleotidyltransferase activity
BBB39_RS15845	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BBB39_RS15855	COG1183	phosphatidylcholine synthase activity
BBB39_RS15860	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BBB39_RS15865	COG0440	acetolactate synthase activity
BBB39_RS15870	COG0028	Belongs to the TPP enzyme family
BBB39_RS15875	COG1289	transmembrane transporter activity
BBB39_RS15880	COG3022	response to hydroperoxide
BBB39_RS15885	COG1028	Short-chain dehydrogenase reductase Sdr
BBB39_RS15895	COG2153	protein acetylation
BBB39_RS15930	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BBB39_RS15935	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BBB39_RS15940	COG1122	ATPase activity
BBB39_RS15945	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BBB39_RS15980	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BBB39_RS15985	COG1674	ftsk spoiiie
BBB39_RS15990	COG0492	ferredoxin-NADP+ reductase activity
BBB39_RS15995	COG1193	negative regulation of DNA recombination
BBB39_RS16005	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BBB39_RS16025	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BBB39_RS16040	COG0612	Peptidase, M16
BBB39_RS16045	COG0484	heat shock protein binding
BBB39_RS16050	COG0443	Heat shock 70 kDa protein
BBB39_RS16060	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BBB39_RS16070	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BBB39_RS16075	COG1420	regulation of RNA biosynthetic process
BBB39_RS16080	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BBB39_RS16085	COG0497	DNA recombination
BBB39_RS16090	COG0735	belongs to the Fur family
BBB39_RS16095	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BBB39_RS16115	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BBB39_RS16130	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BBB39_RS16150	COG3181	Tripartite tricarboxylate transporter family receptor
BBB39_RS16170	COG0583	DNA-binding transcription factor activity
BBB39_RS16190	COG0235	Class ii aldolase
BBB39_RS16195	COG1309	transcriptional regulator
BBB39_RS16200	COG1028	Short-chain dehydrogenase reductase Sdr
BBB39_RS16335	COG0740	serine-type endopeptidase activity
BBB39_RS16345	COG4626	Terminase
BBB39_RS16345	COG1802	Transcriptional regulator
BBB39_RS16410	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BBB39_RS16495	COG0583	DNA-binding transcription factor activity
BBB39_RS16505	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BBB39_RS16510	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BBB39_RS16515	COG0167	dihydroorotate dehydrogenase activity
BBB39_RS16530	COG1414	Transcriptional regulator
BBB39_RS16550	COG0513	Belongs to the DEAD box helicase family
BBB39_RS16575	COG0429	hydrolase of the alpha beta-hydrolase fold
BBB39_RS16580	COG4783	chaperone-mediated protein folding
BBB39_RS16590	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BBB39_RS16595	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BBB39_RS16610	COG0006	proline dipeptidase activity
BBB39_RS16615	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BBB39_RS16635	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BBB39_RS16640	COG0632	four-way junction helicase activity
BBB39_RS16645	COG1090	epimerase
BBB39_RS16650	COG2255	four-way junction helicase activity
BBB39_RS16655	COG0514	ATP-dependent DNA helicase (RecQ)
BBB39_RS16670	COG3290	protein histidine kinase activity
BBB39_RS16675	COG1294	oxidase, subunit
BBB39_RS16685	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BBB39_RS16690	COG0850	regulation of cytokinetic process
BBB39_RS16695	COG2894	cell division
BBB39_RS16700	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BBB39_RS16720	COG0488	(ABC) transporter
BBB39_RS16725	COG0697	spore germination
BBB39_RS16745	COG1216	Glycosyl transferase, family 2
BBB39_RS16745	COG0463	Glycosyl transferase, family 2
BBB39_RS16760	COG3949	Membrane
BBB39_RS16770	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BBB39_RS16785	COG3181	Tripartite tricarboxylate transporter family receptor
BBB39_RS16795	COG0583	DNA-binding transcription factor activity
BBB39_RS16800	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BBB39_RS16805	COG1538	Outer membrane efflux protein
BBB39_RS16810	COG1136	(ABC) transporter
BBB39_RS16810	COG0577	efflux transmembrane transporter activity
BBB39_RS16815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BBB39_RS16820	COG0583	DNA-binding transcription factor activity
BBB39_RS16845	COG0259	pyridoxamine-phosphate oxidase activity
BBB39_RS16850	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BBB39_RS16855	COG0579	oxidoreductase
BBB39_RS16865	COG3210	domain, Protein
BBB39_RS16875	COG0583	DNA-binding transcription factor activity
BBB39_RS16880	COG1960	acyl-CoA dehydrogenase activity
BBB39_RS16890	COG0405	Gamma-glutamyltransferase
BBB39_RS16900	COG0860	N-Acetylmuramoyl-L-alanine amidase
BBB39_RS16905	COG0802	atpase or kinase
BBB39_RS16910	COG0114	fumarate hydratase activity
BBB39_RS16920	COG3181	Tripartite tricarboxylate transporter family receptor
BBB39_RS16925	COG3064	Membrane
BBB39_RS16925	COG3210	domain, Protein
BBB39_RS16925	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
BBB39_RS16925	COG3064	Membrane
BBB39_RS16925	COG3210	domain, Protein
BBB39_RS16925	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
BBB39_RS16930	COG0586	Pfam SNARE associated Golgi protein
BBB39_RS16935	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BBB39_RS16940	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BBB39_RS16945	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BBB39_RS16960	COG0617	tRNA 3'-terminal CCA addition
BBB39_RS16980	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BBB39_RS16985	COG2301	Belongs to the HpcH HpaI aldolase family
BBB39_RS16995	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
BBB39_RS17000	COG1024	Enoyl-CoA hydratase
BBB39_RS17010	COG1960	acyl-CoA dehydrogenase activity
BBB39_RS17020	COG0183	Belongs to the thiolase family
BBB39_RS17025	COG0318	PFAM AMP-dependent synthetase and ligase
BBB39_RS17035	COG3181	Tripartite tricarboxylate transporter family receptor
BBB39_RS17045	COG1028	Short-chain dehydrogenase reductase Sdr
BBB39_RS17050	COG2030	dehydratase
BBB39_RS17065	COG1024	Enoyl-CoA hydratase
BBB39_RS17070	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BBB39_RS17100	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BBB39_RS17105	COG0066	3-isopropylmalate dehydratase activity
BBB39_RS17120	COG0752	glycyl-tRNA synthetase alpha subunit
BBB39_RS17125	COG0751	glycine-tRNA ligase activity
BBB39_RS17130	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BBB39_RS17135	COG0204	Acyl-transferase
BBB39_RS17150	COG0242	peptide deformylase activity
BBB39_RS17155	COG1960	acyl-CoA dehydrogenase activity
BBB39_RS17160	COG0700	Nucleoside recognition
BBB39_RS17165	COG0469	pyruvate kinase activity
BBB39_RS17170	COG1929	Belongs to the glycerate kinase type-1 family
BBB39_RS17180	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BBB39_RS17185	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BBB39_RS17190	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BBB39_RS17200	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BBB39_RS17210	COG0667	Aldo Keto reductase
BBB39_RS17220	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BBB39_RS17225	COG4106	trans-aconitate 2-methyltransferase activity
BBB39_RS17240	COG1294	oxidase, subunit
BBB39_RS17245	COG1271	oxidase subunit
BBB39_RS17275	COG2982	Protein involved in outer membrane biogenesis
BBB39_RS17280	COG2818	Glycosylase
BBB39_RS17285	COG0727	PFAM Uncharacterised protein family (UPF0153)
BBB39_RS17310	COG0604	alcohol dehydrogenase
BBB39_RS17310	COG1028	Short-chain dehydrogenase reductase Sdr
BBB39_RS17310	COG3321	synthase
BBB39_RS17315	COG0156	8-amino-7-oxononanoate synthase activity
BBB39_RS17320	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BBB39_RS17335	COG2089	acid synthase
BBB39_RS17350	COG1083	cytidylyl-transferase
BBB39_RS17355	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BBB39_RS17360	COG1086	Polysaccharide biosynthesis protein
BBB39_RS17400	COG0300	oxidoreductase activity
BBB39_RS17410	COG1464	Belongs to the NlpA lipoprotein family
BBB39_RS17415	COG2011	ABC-type metal ion transport system permease component
BBB39_RS17420	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BBB39_RS17425	COG1501	Belongs to the glycosyl hydrolase 31 family
BBB39_RS17430	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
BBB39_RS17430	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BBB39_RS17440	COG0318	PFAM AMP-dependent synthetase and ligase
BBB39_RS17445	COG1473	amidohydrolase
BBB39_RS17450	COG0583	DNA-binding transcription factor activity
BBB39_RS17455	COG2855	membrane
BBB39_RS17465	COG2239	Acts as a magnesium transporter
BBB39_RS17480	COG1522	sequence-specific DNA binding
BBB39_RS17500	COG0653	protein targeting
BBB39_RS17505	COG0739	heme binding
BBB39_RS17520	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BBB39_RS17525	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BBB39_RS17535	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BBB39_RS17540	COG1181	Belongs to the D-alanine--D-alanine ligase family
BBB39_RS17545	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BBB39_RS17550	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BBB39_RS17560	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BBB39_RS17565	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BBB39_RS17570	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BBB39_RS17580	COG3116	cell division
BBB39_RS17585	COG0275	rRNA processing
BBB39_RS17590	COG2001	Belongs to the MraZ family
BBB39_RS17600	COG0488	(ABC) transporter
BBB39_RS17605	COG0418	dihydroorotase activity
BBB39_RS17610	COG1473	amidohydrolase
BBB39_RS17660	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BBB39_RS17665	COG4654	Cytochrome c, class I
BBB39_RS17670	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BBB39_RS17705	COG2084	Dehydrogenase
BBB39_RS17710	COG0583	DNA-binding transcription factor activity
BBB39_RS17740	COG0442	prolyl-tRNA aminoacylation
BBB39_RS17745	COG0824	Thioesterase
BBB39_RS17755	COG0848	biopolymer transport protein
BBB39_RS17765	COG0823	Involved in the tonB-independent uptake of proteins
BBB39_RS17785	COG2267	carboxylic ester hydrolase activity
BBB39_RS17790	COG1522	sequence-specific DNA binding
BBB39_RS17810	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BBB39_RS17835	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BBB39_RS17840	COG0463	Glycosyl transferase, family 2
BBB39_RS17855	COG1671	Belongs to the UPF0178 family
BBB39_RS17865	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BBB39_RS17870	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BBB39_RS17875	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BBB39_RS17880	COG0328	RNA-DNA hybrid ribonuclease activity
BBB39_RS17885	COG2226	methyltransferase
BBB39_RS17890	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BBB39_RS17895	COG0741	lytic transglycosylase activity
BBB39_RS17895	COG1388	LysM domain
BBB39_RS17905	COG2979	Protein of unknown function (DUF533)
BBB39_RS17940	COG2816	NAD+ diphosphatase activity
BBB39_RS17970	COG0583	DNA-binding transcription factor activity
BBB39_RS17975	COG4948	Mandelate Racemase Muconate Lactonizing
BBB39_RS17980	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BBB39_RS17990	COG3181	Tripartite tricarboxylate transporter family receptor
BBB39_RS17995	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BBB39_RS18005	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BBB39_RS18020	COG3246	L-lysine catabolic process to acetate
BBB39_RS18025	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BBB39_RS18040	COG0668	transmembrane transport
BBB39_RS18045	COG1621	beta-fructofuranosidase activity
BBB39_RS18060	COG0697	spore germination
BBB39_RS18065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BBB39_RS18070	COG2015	COG2015, Alkyl sulfatase and related hydrolases
BBB39_RS18085	COG4977	sequence-specific DNA binding
BBB39_RS18095	COG2072	flavoprotein involved in K transport
BBB39_RS18100	COG0657	acetylesterase activity
BBB39_RS18105	COG1454	alcohol dehydrogenase
BBB39_RS18115	COG0679	Auxin Efflux Carrier
BBB39_RS18135	COG0028	Belongs to the TPP enzyme family
BBB39_RS18150	COG0436	Aminotransferase
BBB39_RS18155	COG0583	DNA-binding transcription factor activity
BBB39_RS18165	COG0583	DNA-binding transcription factor activity
BBB39_RS18190	COG1982	Orn Lys Arg decarboxylase major
BBB39_RS18195	COG0531	amino acid
BBB39_RS18215	COG0477	Major facilitator Superfamily
BBB39_RS18230	COG2719	SpoVR family
BBB39_RS18235	COG2718	Belongs to the UPF0229 family
BBB39_RS18240	COG2766	serine protein kinase
BBB39_RS18260	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BBB39_RS18260	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BBB39_RS18265	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BBB39_RS18270	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BBB39_RS18275	COG1881	PFAM PEBP family protein
BBB39_RS18280	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BBB39_RS18285	COG4942	peptidase
BBB39_RS18290	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BBB39_RS18295	COG0316	Belongs to the HesB IscA family
BBB39_RS18305	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BBB39_RS18310	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BBB39_RS18315	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BBB39_RS18320	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BBB39_RS18335	COG0312	modulator of DNA gyrase
BBB39_RS18340	COG3028	Belongs to the UPF0307 family
BBB39_RS18350	COG0045	succinate-CoA ligase (ADP-forming) activity
BBB39_RS18350	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BBB39_RS18350	COG1042	CoA-binding domain protein
BBB39_RS18350	COG0045	succinate-CoA ligase (ADP-forming) activity
BBB39_RS18350	COG1042	CoA-binding domain protein
BBB39_RS18350	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BBB39_RS18355	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BBB39_RS18370	COG0583	DNA-binding transcription factor activity
BBB39_RS18380	COG3181	Tripartite tricarboxylate transporter family receptor
BBB39_RS18430	COG2264	protein methyltransferase activity
BBB39_RS18435	COG0439	Biotin carboxylase
BBB39_RS18440	COG0511	ligase activity, forming carbon-carbon bonds
BBB39_RS18445	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BBB39_RS18450	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BBB39_RS18455	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BBB39_RS18460	COG3150	esterase
BBB39_RS18465	COG0557	exoribonuclease II activity
BBB39_RS18475	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BBB39_RS18480	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BBB39_RS18490	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BBB39_RS18500	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BBB39_RS18505	COG0540	Belongs to the ATCase OTCase family
BBB39_RS18510	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BBB39_RS18515	COG1678	Uncharacterized ACR, COG1678
BBB39_RS18525	COG0351	phosphomethylpyrimidine kinase
BBB39_RS18530	COG0352	thiamine-phosphate diphosphorylase activity
BBB39_RS18535	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BBB39_RS18560	COG1960	acyl-CoA dehydrogenase activity
BBB39_RS18565	COG1024	Enoyl-CoA hydratase
BBB39_RS18570	COG1028	Short-chain dehydrogenase reductase Sdr
BBB39_RS18640	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BBB39_RS18655	COG3539	Fimbrial protein
BBB39_RS18660	COG3539	Fimbrial protein
BBB39_RS18665	COG3539	Fimbrial protein
BBB39_RS18670	COG3539	Fimbrial protein
BBB39_RS18675	COG3539	Fimbrial protein
BBB39_RS18680	COG3539	Fimbrial protein
BBB39_RS18685	COG3539	Fimbrial protein
BBB39_RS18690	COG3539	Fimbrial protein
BBB39_RS18695	COG3539	Fimbrial protein
BBB39_RS18700	COG3539	Fimbrial protein
BBB39_RS18705	COG3539	Fimbrial protein
BBB39_RS18710	COG3539	Fimbrial protein
BBB39_RS18715	COG3539	Fimbrial protein
BBB39_RS18720	COG3539	Fimbrial protein
BBB39_RS18730	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BBB39_RS18745	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
BBB39_RS18755	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BBB39_RS18770	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BBB39_RS18775	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BBB39_RS18785	COG0477	Major facilitator Superfamily
BBB39_RS18805	COG1126	abc transporter atp-binding protein
BBB39_RS18810	COG0765	amino acid transport
BBB39_RS18815	COG4597	amino acid ABC transporter
BBB39_RS18820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BBB39_RS18825	COG2884	Cell division ATP-binding protein ftsE
BBB39_RS18830	COG2177	Part of the ABC transporter FtsEX involved in
BBB39_RS18835	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BBB39_RS18845	COG1194	a g-specific adenine glycosylase
BBB39_RS18855	COG1028	Short-chain dehydrogenase reductase Sdr
BBB39_RS18865	COG1802	Transcriptional regulator
BBB39_RS18875	COG2226	methyltransferase
BBB39_RS18885	COG4206	TonB-dependent receptor
BBB39_RS18890	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BBB39_RS18895	COG2022	thiamine diphosphate biosynthetic process
BBB39_RS18900	COG0351	phosphomethylpyrimidine kinase
BBB39_RS18905	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BBB39_RS18910	COG1538	Outer membrane efflux protein
BBB39_RS18915	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BBB39_RS18925	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BBB39_RS18940	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BBB39_RS18970	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BBB39_RS19005	COG2226	methyltransferase
BBB39_RS19010	COG0745	RESPONSE REGULATOR receiver
BBB39_RS19015	COG5002	protein histidine kinase activity
BBB39_RS19025	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BBB39_RS19040	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BBB39_RS19045	COG1984	allophanate hydrolase subunit 2
BBB39_RS19055	COG1802	Transcriptional regulator
BBB39_RS19065	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BBB39_RS19070	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BBB39_RS19080	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BBB39_RS19085	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BBB39_RS19090	COG4988	ABC transporter
BBB39_RS19100	COG1294	oxidase, subunit
BBB39_RS19115	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BBB39_RS19125	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BBB39_RS19140	COG1137	ATPase activity
BBB39_RS19145	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BBB39_RS19155	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BBB39_RS19160	COG1660	Displays ATPase and GTPase activities
BBB39_RS19175	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BBB39_RS19180	COG0792	nuclease activity
BBB39_RS19185	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BBB39_RS19190	COG2823	Periplasmic or secreted lipoprotein
BBB39_RS19205	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BBB39_RS19215	COG1309	transcriptional regulator
BBB39_RS19220	COG0471	metal ion transport
BBB39_RS19225	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BBB39_RS19230	COG0772	Belongs to the SEDS family
BBB39_RS19245	COG1792	Involved in formation and maintenance of cell shape
BBB39_RS19250	COG1077	Cell shape determining protein MreB Mrl
BBB39_RS19255	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BBB39_RS19260	COG0154	amidase activity
BBB39_RS19265	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BBB39_RS19270	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BBB39_RS19280	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BBB39_RS19285	COG2860	membrane
BBB39_RS19295	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BBB39_RS19300	COG2223	nitrite transmembrane transporter activity
BBB39_RS19305	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BBB39_RS19305	COG2813	Specifically methylates the guanine in position
BBB39_RS19310	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BBB39_RS19325	COG2918	glutathione biosynthetic process
BBB39_RS19330	COG3040	lipid binding
BBB39_RS19350	COG1250	3-hydroxyacyl-CoA dehydrogenase
BBB39_RS19360	COG1960	acyl-CoA dehydrogenase activity
BBB39_RS19375	COG1024	Enoyl-CoA hydratase
BBB39_RS19380	COG1024	Enoyl-CoA hydratase
BBB39_RS19385	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BBB39_RS19395	COG0747	negative chemotaxis
BBB39_RS19405	COG0601	transmembrane transport
BBB39_RS19410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BBB39_RS19415	COG0444	Belongs to the ABC transporter superfamily
BBB39_RS19420	COG4608	Belongs to the ABC transporter superfamily
BBB39_RS19435	COG0210	DNA helicase
BBB39_RS19440	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BBB39_RS19445	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BBB39_RS19455	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BBB39_RS19465	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BBB39_RS19470	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BBB39_RS19475	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BBB39_RS19480	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BBB39_RS19490	COG0356	it plays a direct role in the translocation of protons across the membrane
BBB39_RS19500	COG1024	Enoyl-CoA hydratase
BBB39_RS19520	COG0037	tRNA processing
BBB39_RS19525	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BBB39_RS19530	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BBB39_RS19535	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BBB39_RS19540	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
BBB39_RS19545	COG2967	ApaG domain
BBB39_RS19550	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BBB39_RS19555	COG0546	phosphoglycolate phosphatase activity
BBB39_RS19565	COG0512	Glutamine amidotransferase of anthranilate synthase
BBB39_RS19570	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BBB39_RS19575	COG0134	indole-3-glycerol-phosphate synthase activity
BBB39_RS19605	COG3276	selenocysteine insertion sequence binding
BBB39_RS19620	COG2864	formate dehydrogenase
BBB39_RS19625	COG0437	4 iron, 4 sulfur cluster binding
BBB39_RS19630	COG3383	formate dehydrogenase (NAD+) activity
BBB39_RS19630	COG0243	molybdopterin cofactor binding
BBB39_RS19635	COG0243	molybdopterin cofactor binding
BBB39_RS19635	COG3383	formate dehydrogenase (NAD+) activity
BBB39_RS19645	COG1607	acyl-coa hydrolase
BBB39_RS19670	COG3712	iron ion homeostasis
BBB39_RS19675	COG4771	TonB-dependent receptor
BBB39_RS19675	COG1629	transport
BBB39_RS19680	COG3720	iron ion transport
BBB39_RS19685	COG4558	Periplasmic binding protein
BBB39_RS19690	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BBB39_RS19695	COG1120	ATPase activity
BBB39_RS19705	COG1683	Conserved Protein
BBB39_RS19715	COG3145	DNA-N1-methyladenine dioxygenase activity
BBB39_RS19725	COG2169	Transcriptional regulator
BBB39_RS19725	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BBB39_RS19740	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BBB39_RS19745	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BBB39_RS19745	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BBB39_RS19745	COG0506	proline dehydrogenase activity
BBB39_RS19755	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BBB39_RS19760	COG0477	Major facilitator Superfamily
BBB39_RS19765	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BBB39_RS19770	COG1278	Cold shock
BBB39_RS19775	COG5383	Protein conserved in bacteria
BBB39_RS19795	COG3181	Tripartite tricarboxylate transporter family receptor
BBB39_RS19800	COG0251	oxidation-reduction process
BBB39_RS19820	COG0443	Heat shock 70 kDa protein
BBB39_RS19825	COG0583	DNA-binding transcription factor activity
BBB39_RS19830	COG2271	Major facilitator Superfamily
BBB39_RS19850	COG1454	alcohol dehydrogenase
BBB39_RS19930	COG1522	sequence-specific DNA binding
BBB39_RS19945	COG2814	Major facilitator Superfamily
BBB39_RS19950	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BBB39_RS19965	COG1999	signal sequence binding
BBB39_RS19970	COG0109	protoheme IX farnesyltransferase activity
BBB39_RS19975	COG1612	heme a metabolic process
BBB39_RS19995	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BBB39_RS20000	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BBB39_RS20015	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BBB39_RS20030	COG0070	glutamate synthase
BBB39_RS20030	COG0067	glutamate synthase
BBB39_RS20030	COG0069	glutamate synthase activity
BBB39_RS20060	COG3021	interspecies interaction between organisms
BBB39_RS20085	COG1984	allophanate hydrolase subunit 2
BBB39_RS20095	COG0439	Biotin carboxylase
BBB39_RS20100	COG0511	ligase activity, forming carbon-carbon bonds
BBB39_RS20105	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BBB39_RS20125	COG1127	ABC transporter
BBB39_RS20130	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BBB39_RS20135	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BBB39_RS20150	COG1131	(ABC) transporter
BBB39_RS20155	COG0842	Transport permease protein
BBB39_RS20165	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BBB39_RS20170	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BBB39_RS20175	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BBB39_RS20180	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BBB39_RS20185	COG0131	Imidazoleglycerol-phosphate dehydratase
BBB39_RS20195	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BBB39_RS20200	COG0107	imidazoleglycerol-phosphate synthase activity
BBB39_RS20205	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BBB39_RS20210	COG0140	phosphoribosyl-ATP diphosphatase activity
BBB39_RS20215	COG0537	adenosine 5'-monophosphoramidase activity
BBB39_RS20220	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BBB39_RS20225	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BBB39_RS20235	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BBB39_RS20240	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BBB39_RS20245	COG1970	mechanosensitive ion channel activity
BBB39_RS20250	COG0723	plastoquinol--plastocyanin reductase activity
BBB39_RS20255	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BBB39_RS20260	COG2857	Cytochrome c1
BBB39_RS20265	COG0625	glutathione transferase activity
BBB39_RS20270	COG2969	positive regulation of protein catabolic process
BBB39_RS20280	COG0583	DNA-binding transcription factor activity
BBB39_RS20285	COG1024	Enoyl-CoA hydratase
BBB39_RS20290	COG1960	acyl-CoA dehydrogenase activity
BBB39_RS20300	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BBB39_RS20330	COG0697	spore germination
BBB39_RS20360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BBB39_RS20365	COG4172	Belongs to the ABC transporter superfamily
BBB39_RS20370	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BBB39_RS20385	COG1280	lysine exporter protein (LysE YggA)
BBB39_RS20390	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BBB39_RS20410	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BBB39_RS20420	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BBB39_RS20425	COG0154	amidase activity
BBB39_RS20430	COG1609	Transcriptional regulator
BBB39_RS20450	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BBB39_RS20455	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BBB39_RS20460	COG3842	ATPase activity
BBB39_RS20470	COG1175	transmembrane transport
BBB39_RS20475	COG0395	ABC-type sugar transport system, permease component
BBB39_RS20490	COG0018	arginyl-trna synthetase
BBB39_RS20500	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BBB39_RS20510	COG1280	lysine exporter protein (LysE YggA)
BBB39_RS20530	COG3181	Tripartite tricarboxylate transporter family receptor
BBB39_RS20535	COG0583	DNA-binding transcription factor activity
BBB39_RS20550	COG3181	Tripartite tricarboxylate transporter family receptor
BBB39_RS20555	COG1473	amidohydrolase
BBB39_RS20560	COG1960	acyl-CoA dehydrogenase activity
BBB39_RS20565	COG0183	Belongs to the thiolase family
BBB39_RS20570	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BBB39_RS20585	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BBB39_RS20595	COG2358	TRAP transporter, solute receptor (TAXI family
BBB39_RS20605	COG2922	Belongs to the Smg family
BBB39_RS20610	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BBB39_RS20620	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BBB39_RS20620	COG0551	DNA topoisomerase type I activity
BBB39_RS20630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BBB39_RS20635	COG0765	amino acid transport
BBB39_RS20640	COG1126	abc transporter atp-binding protein
BBB39_RS20645	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BBB39_RS20650	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BBB39_RS20655	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BBB39_RS20660	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BBB39_RS20665	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BBB39_RS20670	COG1028	Short-chain dehydrogenase reductase Sdr
BBB39_RS20675	COG1012	belongs to the aldehyde dehydrogenase family
BBB39_RS20685	COG0028	Belongs to the TPP enzyme family
BBB39_RS20690	COG1522	sequence-specific DNA binding
BBB39_RS20695	COG3781	membrane
BBB39_RS20725	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BBB39_RS20735	COG1304	FMN binding
BBB39_RS20740	COG1254	Belongs to the acylphosphatase family
BBB39_RS20750	COG0154	amidase activity
BBB39_RS20755	COG1414	Transcriptional regulator
BBB39_RS20760	COG2814	Major facilitator Superfamily
BBB39_RS20765	COG0697	spore germination
BBB39_RS20780	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BBB39_RS20785	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BBB39_RS20790	COG0594	ribonuclease P activity
BBB39_RS20795	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BBB39_RS20800	COG0706	membrane insertase activity
BBB39_RS20805	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
BBB39_RS20815	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BBB39_RS20825	COG2175	clavaminate synthase activity
BBB39_RS20830	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BBB39_RS20840	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BBB39_RS20855	COG1505	serine-type exopeptidase activity
BBB39_RS20865	COG0281	malic enzyme
BBB39_RS20865	COG0280	phosphate acetyltransferase
BBB39_RS20895	COG0583	DNA-binding transcription factor activity
BBB39_RS20900	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BBB39_RS20905	COG3181	Tripartite tricarboxylate transporter family receptor
BBB39_RS20910	COG0436	Aminotransferase
BBB39_RS20915	COG3180	Ammonia monooxygenase
BBB39_RS20920	COG1278	Cold shock