locus-tag	class	description
BAFHLJ01_RS00010	COG1472	Belongs to the glycosyl hydrolase 3 family
BAFHLJ01_RS00050	COG0736	holo-[acyl-carrier-protein] synthase activity
BAFHLJ01_RS00075	COG0572	uridine kinase
BAFHLJ01_RS00085	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BAFHLJ01_RS00105	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BAFHLJ01_RS00110	COG2255	four-way junction helicase activity
BAFHLJ01_RS00115	COG0632	four-way junction helicase activity
BAFHLJ01_RS00125	COG0217	transcriptional regulatory protein
BAFHLJ01_RS00130	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BAFHLJ01_RS00155	COG0681	Belongs to the peptidase S26 family
BAFHLJ01_RS00165	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BAFHLJ01_RS00220	COG1196	nuclear chromosome segregation
BAFHLJ01_RS00225	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BAFHLJ01_RS00250	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BAFHLJ01_RS00260	COG0149	triose-phosphate isomerase activity
BAFHLJ01_RS00265	COG0126	phosphoglycerate kinase activity
BAFHLJ01_RS00285	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BAFHLJ01_RS00305	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BAFHLJ01_RS00325	COG0561	phosphatase activity
BAFHLJ01_RS00330	COG2309	aminopeptidase activity
BAFHLJ01_RS00375	COG4591	ABC-type transport system involved in lipoprotein release permease component
BAFHLJ01_RS00380	COG1136	(ABC) transporter
BAFHLJ01_RS00410	COG0606	chelatase, subunit chli
BAFHLJ01_RS00415	COG0039	L-malate dehydrogenase activity
BAFHLJ01_RS00420	COG0481	GTPase activity
BAFHLJ01_RS00445	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
BAFHLJ01_RS00450	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
BAFHLJ01_RS00460	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
BAFHLJ01_RS00475	COG1162	GTPase activity
BAFHLJ01_RS00485	COG0017	Asparaginyl-tRNA synthetase
BAFHLJ01_RS00500	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BAFHLJ01_RS00515	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BAFHLJ01_RS00535	COG0305	Participates in initiation and elongation during chromosome replication
BAFHLJ01_RS00540	COG0359	binds to the 23S rRNA
BAFHLJ01_RS00545	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BAFHLJ01_RS00555	COG0360	Binds together with S18 to 16S ribosomal RNA
BAFHLJ01_RS00560	COG2190	(PTS) system
BAFHLJ01_RS00560	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BAFHLJ01_RS00560	COG1263	PTS System
BAFHLJ01_RS00575	COG4589	Belongs to the CDS family
BAFHLJ01_RS00590	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BAFHLJ01_RS00595	COG0052	Belongs to the universal ribosomal protein uS2 family
BAFHLJ01_RS00615	COG0539	negative regulation of cytoplasmic translation
BAFHLJ01_RS00620	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BAFHLJ01_RS00635	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BAFHLJ01_RS00655	COG0124	histidyl-tRNA synthetase
BAFHLJ01_RS00660	COG0768	penicillin binding
BAFHLJ01_RS00665	COG1022	Amp-dependent synthetase and ligase
BAFHLJ01_RS00690	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BAFHLJ01_RS00700	COG4176	ABC-type proline glycine betaine transport system permease component
BAFHLJ01_RS00705	COG3448	diguanylate cyclase activity
BAFHLJ01_RS00705	COG4175	Glycine betaine
BAFHLJ01_RS00720	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BAFHLJ01_RS00725	COG0363	glucosamine-6-phosphate deaminase activity
BAFHLJ01_RS00735	COG0653	protein targeting
BAFHLJ01_RS00790	COG1640	4-alpha-glucanotransferase
BAFHLJ01_RS00805	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BAFHLJ01_RS00840	COG0714	Associated with various cellular activities
BAFHLJ01_RS00845	COG0357	Ribosomal RNA small subunit methyltransferase G
BAFHLJ01_RS00850	COG0445	tRNA wobble uridine modification
BAFHLJ01_RS00855	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BAFHLJ01_RS00870	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BAFHLJ01_RS00875	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
BAFHLJ01_RS00880	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BAFHLJ01_RS00900	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BAFHLJ01_RS00905	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BAFHLJ01_RS00910	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BAFHLJ01_RS00925	COG0084	hydrolase, TatD family'
BAFHLJ01_RS00970	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BAFHLJ01_RS00980	COG4536	flavin adenine dinucleotide binding
BAFHLJ01_RS01010	COG0742	ribosomal rna small subunit methyltransferase
BAFHLJ01_RS01015	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BAFHLJ01_RS01035	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BAFHLJ01_RS01055	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BAFHLJ01_RS01065	COG0573	inorganic phosphate transmembrane transporter activity
BAFHLJ01_RS01070	COG0581	inorganic phosphate transmembrane transporter activity
BAFHLJ01_RS01075	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BAFHLJ01_RS01085	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BAFHLJ01_RS01090	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BAFHLJ01_RS01105	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BAFHLJ01_RS01125	COG0254	rRNA binding
BAFHLJ01_RS01155	COG0012	GTP binding
BAFHLJ01_RS01175	COG1428	Deoxynucleoside kinase
BAFHLJ01_RS01180	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BAFHLJ01_RS01185	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BAFHLJ01_RS01210	COG0739	heme binding
BAFHLJ01_RS01215	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BAFHLJ01_RS01240	COG0495	leucyl-tRNA aminoacylation
BAFHLJ01_RS01255	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BAFHLJ01_RS01260	COG0739	heme binding
BAFHLJ01_RS01275	COG1968	undecaprenyl-diphosphatase activity
BAFHLJ01_RS01300	COG0681	Belongs to the peptidase S26 family
BAFHLJ01_RS01305	COG0443	Heat shock 70 kDa protein
BAFHLJ01_RS01385	COG1360	Flagellar Motor Protein
BAFHLJ01_RS01395	COG1582	Flagellar protein (FlbD)
BAFHLJ01_RS01405	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BAFHLJ01_RS01465	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BAFHLJ01_RS01490	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BAFHLJ01_RS01500	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BAFHLJ01_RS01515	COG0275	rRNA processing
BAFHLJ01_RS01540	COG0835	chemotaxis
BAFHLJ01_RS01635	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BAFHLJ01_RS01640	COG0444	Belongs to the ABC transporter superfamily
BAFHLJ01_RS01645	COG4608	Belongs to the ABC transporter superfamily
BAFHLJ01_RS01655	COG0148	phosphopyruvate hydratase activity
BAFHLJ01_RS01660	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BAFHLJ01_RS01665	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BAFHLJ01_RS01680	COG0154	amidase activity
BAFHLJ01_RS01690	COG0210	DNA helicase
BAFHLJ01_RS01725	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BAFHLJ01_RS01765	COG0793	Belongs to the peptidase S41A family
BAFHLJ01_RS01770	COG0455	bacterial-type flagellum organization
BAFHLJ01_RS01775	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BAFHLJ01_RS01795	COG1362	aminopeptidase activity
BAFHLJ01_RS01805	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BAFHLJ01_RS01810	COG0542	response to heat
BAFHLJ01_RS01815	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BAFHLJ01_RS01820	COG0423	glycine-tRNA ligase activity
BAFHLJ01_RS01825	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BAFHLJ01_RS01840	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BAFHLJ01_RS01845	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BAFHLJ01_RS01850	COG1854	S-ribosylhomocysteine lyase activity
BAFHLJ01_RS01865	COG2239	Acts as a magnesium transporter
BAFHLJ01_RS01875	COG1744	ABC transporter substrate-binding protein PnrA-like
BAFHLJ01_RS01880	COG1744	ABC transporter substrate-binding protein PnrA-like
BAFHLJ01_RS01890	COG1744	ABC transporter substrate-binding protein PnrA-like
BAFHLJ01_RS01905	COG0049	tRNA binding
BAFHLJ01_RS01915	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BAFHLJ01_RS01920	COG0085	RNA polymerase activity
BAFHLJ01_RS01925	COG0222	ribosome binding
BAFHLJ01_RS01930	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BAFHLJ01_RS01935	COG0081	regulation of translation
BAFHLJ01_RS01995	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BAFHLJ01_RS02025	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BAFHLJ01_RS02025	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BAFHLJ01_RS02025	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BAFHLJ01_RS02030	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BAFHLJ01_RS02030	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BAFHLJ01_RS02030	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BAFHLJ01_RS02110	COG0561	phosphatase activity
BAFHLJ01_RS02115	COG2094	Belongs to the DNA glycosylase MPG family
BAFHLJ01_RS02145	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BAFHLJ01_RS02160	COG1739	Uncharacterized protein family UPF0029
BAFHLJ01_RS02205	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BAFHLJ01_RS02210	COG0594	ribonuclease P activity
BAFHLJ01_RS02215	COG0706	membrane insertase activity
BAFHLJ01_RS02235	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BAFHLJ01_RS02255	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BAFHLJ01_RS02270	COG0668	transmembrane transport
BAFHLJ01_RS02290	COG0322	excinuclease ABC activity
BAFHLJ01_RS02335	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BAFHLJ01_RS02340	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BAFHLJ01_RS02360	COG1137	ATPase activity
BAFHLJ01_RS02405	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BAFHLJ01_RS02415	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BAFHLJ01_RS02420	COG0088	Forms part of the polypeptide exit tunnel
BAFHLJ01_RS02430	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BAFHLJ01_RS02440	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BAFHLJ01_RS02445	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BAFHLJ01_RS02450	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BAFHLJ01_RS02455	COG0255	Belongs to the universal ribosomal protein uL29 family
BAFHLJ01_RS02460	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BAFHLJ01_RS02465	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BAFHLJ01_RS02470	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BAFHLJ01_RS02475	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BAFHLJ01_RS02480	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BAFHLJ01_RS02485	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BAFHLJ01_RS02490	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BAFHLJ01_RS02495	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BAFHLJ01_RS02500	COG1841	ribosomal large subunit assembly
BAFHLJ01_RS02505	COG0200	Binds to the 23S rRNA
BAFHLJ01_RS02515	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BAFHLJ01_RS02520	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BAFHLJ01_RS02530	COG0202	RNA polymerase activity
BAFHLJ01_RS02535	COG0203	ribosomal protein L17
BAFHLJ01_RS02540	COG1418	mRNA catabolic process
BAFHLJ01_RS02545	COG1692	metallophosphoesterase
BAFHLJ01_RS02550	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BAFHLJ01_RS02585	COG0072	phenylalanine-tRNA ligase activity
BAFHLJ01_RS02605	COG0443	Heat shock 70 kDa protein
BAFHLJ01_RS02610	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BAFHLJ01_RS02615	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BAFHLJ01_RS02615	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BAFHLJ01_RS02640	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BAFHLJ01_RS02665	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BAFHLJ01_RS02665	COG0321	lipoyl(octanoyl) transferase activity
BAFHLJ01_RS02670	COG0708	Exodeoxyribonuclease III
BAFHLJ01_RS02680	COG0612	Peptidase, M16
BAFHLJ01_RS02710	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BAFHLJ01_RS02765	COG2201	protein-glutamate methylesterase activity
BAFHLJ01_RS02810	COG0326	Molecular chaperone. Has ATPase activity
BAFHLJ01_RS02845	COG2198	Histidine kinase
BAFHLJ01_RS02845	COG0643	Histidine kinase
BAFHLJ01_RS02860	COG0745	RESPONSE REGULATOR receiver
BAFHLJ01_RS02870	COG0528	UMP kinase activity
BAFHLJ01_RS02875	COG1216	Glycosyl transferase, family 2
BAFHLJ01_RS02880	COG1131	(ABC) transporter
BAFHLJ01_RS02890	COG0504	CTP synthase activity
BAFHLJ01_RS02905	COG0840	transmembrane signaling receptor activity
BAFHLJ01_RS02940	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BAFHLJ01_RS02945	COG2348	transferase activity, transferring amino-acyl groups
BAFHLJ01_RS02950	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BAFHLJ01_RS02950	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BAFHLJ01_RS02955	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BAFHLJ01_RS02965	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BAFHLJ01_RS02980	COG1022	Amp-dependent synthetase and ligase
BAFHLJ01_RS02985	COG0018	arginyl-trna synthetase
BAFHLJ01_RS02995	COG0840	transmembrane signaling receptor activity
BAFHLJ01_RS03000	COG0840	transmembrane signaling receptor activity
BAFHLJ01_RS03000	COG5278	phosphoserine phosphatase activity
BAFHLJ01_RS03005	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BAFHLJ01_RS03010	COG0215	cysteine-tRNA ligase activity
BAFHLJ01_RS03020	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BAFHLJ01_RS03025	COG0484	heat shock protein binding
BAFHLJ01_RS03035	COG1620	l-lactate permease
BAFHLJ01_RS03040	COG1686	Belongs to the peptidase S11 family
BAFHLJ01_RS03045	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BAFHLJ01_RS03055	COG2195	Cleaves the N-terminal amino acid of tripeptides
BAFHLJ01_RS03080	COG0544	peptidyl-prolyl cis-trans isomerase activity
BAFHLJ01_RS03085	COG0740	serine-type endopeptidase activity
BAFHLJ01_RS03100	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BAFHLJ01_RS03120	COG0295	cytidine deaminase activity
BAFHLJ01_RS03145	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BAFHLJ01_RS03160	COG0860	N-Acetylmuramoyl-L-alanine amidase
BAFHLJ01_RS03205	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BAFHLJ01_RS03220	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BAFHLJ01_RS03245	COG1177	transmembrane transport
BAFHLJ01_RS03250	COG1176	ABC-type spermidine putrescine transport system, permease component I
BAFHLJ01_RS03255	COG3842	ATPase activity
BAFHLJ01_RS03265	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
BAFHLJ01_RS03290	COG0459	protein refolding
BAFHLJ01_RS03320	COG0484	heat shock protein binding
BAFHLJ01_RS03325	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BAFHLJ01_RS03330	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BAFHLJ01_RS03335	COG0588	phosphoglycerate mutase activity
BAFHLJ01_RS03345	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BAFHLJ01_RS03375	COG0860	N-Acetylmuramoyl-L-alanine amidase
BAFHLJ01_RS03395	COG0835	chemotaxis
BAFHLJ01_RS03405	COG2201	protein-glutamate methylesterase activity
BAFHLJ01_RS03430	COG3845	ABC transporter
BAFHLJ01_RS03435	COG4603	Belongs to the binding-protein-dependent transport system permease family
BAFHLJ01_RS03440	COG1079	Belongs to the binding-protein-dependent transport system permease family
BAFHLJ01_RS03455	COG0482	sulfurtransferase activity
BAFHLJ01_RS03465	COG1304	FMN binding
BAFHLJ01_RS03505	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BAFHLJ01_RS03515	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BAFHLJ01_RS03530	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BAFHLJ01_RS03535	COG0336	Belongs to the RNA methyltransferase TrmD family
BAFHLJ01_RS03540	COG0335	large ribosomal subunit rRNA binding
BAFHLJ01_RS03550	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BAFHLJ01_RS03555	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BAFHLJ01_RS03560	COG0571	ribonuclease III activity
BAFHLJ01_RS03565	COG0617	tRNA 3'-terminal CCA addition
BAFHLJ01_RS03615	COG1077	Cell shape determining protein MreB Mrl
BAFHLJ01_RS03630	COG0768	penicillin binding
BAFHLJ01_RS03635	COG0772	Belongs to the SEDS family
BAFHLJ01_RS03660	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BAFHLJ01_RS03670	COG0003	Pfam Anion-transporting ATPase
BAFHLJ01_RS03680	COG0446	pyridine nucleotide-disulphide oxidoreductase
BAFHLJ01_RS03690	COG0166	Belongs to the GPI family
BAFHLJ01_RS03695	COG1475	DNA binding
BAFHLJ01_RS03710	COG0009	L-threonylcarbamoyladenylate synthase
BAFHLJ01_RS03715	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BAFHLJ01_RS03725	COG0525	valine-tRNA ligase activity
BAFHLJ01_RS03740	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BAFHLJ01_RS03745	COG0488	(ABC) transporter
BAFHLJ01_RS03770	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BAFHLJ01_RS03775	COG4239	(ABC) transporter, permease
BAFHLJ01_RS03780	COG4168	peptide transport system, permease
BAFHLJ01_RS03810	COG1131	(ABC) transporter
BAFHLJ01_RS03850	COG0739	heme binding
BAFHLJ01_RS03855	COG2204	response regulator
BAFHLJ01_RS03860	COG5002	protein histidine kinase activity
BAFHLJ01_RS03865	COG0470	DNA polymerase III
BAFHLJ01_RS03885	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BAFHLJ01_RS03895	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BAFHLJ01_RS03920	COG4786	Flagellar basal body rod
BAFHLJ01_RS03930	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BAFHLJ01_RS03935	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BAFHLJ01_RS03950	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BAFHLJ01_RS03955	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BAFHLJ01_RS03970	COG2088	sporulation resulting in formation of a cellular spore
BAFHLJ01_RS03980	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BAFHLJ01_RS03985	COG0193	aminoacyl-tRNA hydrolase activity
BAFHLJ01_RS03990	COG0037	tRNA processing
BAFHLJ01_RS04015	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BAFHLJ01_RS04025	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BAFHLJ01_RS04035	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BAFHLJ01_RS04040	COG1040	competence protein
BAFHLJ01_RS04045	COG0779	Required for maturation of 30S ribosomal subunits
BAFHLJ01_RS04060	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BAFHLJ01_RS04065	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BAFHLJ01_RS04070	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BAFHLJ01_RS04075	COG1185	polyribonucleotide nucleotidyltransferase activity
BAFHLJ01_RS04095	COG0343	queuine tRNA-ribosyltransferase activity
BAFHLJ01_RS04115	COG4145	pantothenate transmembrane transporter activity
BAFHLJ01_RS04120	COG0564	pseudouridine synthase activity
BAFHLJ01_RS04130	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BAFHLJ01_RS04135	COG1561	YicC-like family, N-terminal region
BAFHLJ01_RS04140	COG1102	Psort location Cytoplasmic, score
BAFHLJ01_RS04150	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BAFHLJ01_RS04190	COG0419	ATPase involved in DNA repair
BAFHLJ01_RS04195	COG1940	carbohydrate kinase activity
BAFHLJ01_RS04205	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BAFHLJ01_RS04215	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BAFHLJ01_RS04250	COG2235	arginine
BAFHLJ01_RS04260	COG1288	antiporter activity