locus-tag	class	description
BAFK78_RS00010	COG1472	Belongs to the glycosyl hydrolase 3 family
BAFK78_RS00050	COG0736	holo-[acyl-carrier-protein] synthase activity
BAFK78_RS00060	COG0101	tRNA pseudouridine synthase activity
BAFK78_RS00075	COG0572	uridine kinase
BAFK78_RS00085	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BAFK78_RS00105	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BAFK78_RS00110	COG2255	four-way junction helicase activity
BAFK78_RS00115	COG0632	four-way junction helicase activity
BAFK78_RS00125	COG0217	transcriptional regulatory protein
BAFK78_RS00130	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BAFK78_RS00155	COG0681	Belongs to the peptidase S26 family
BAFK78_RS00165	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BAFK78_RS00220	COG1196	nuclear chromosome segregation
BAFK78_RS00225	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BAFK78_RS00240	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BAFK78_RS00255	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BAFK78_RS00265	COG0149	triose-phosphate isomerase activity
BAFK78_RS00270	COG0126	phosphoglycerate kinase activity
BAFK78_RS00290	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BAFK78_RS00310	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BAFK78_RS00330	COG0561	phosphatase activity
BAFK78_RS00335	COG2309	aminopeptidase activity
BAFK78_RS00370	COG0552	protein localization to endoplasmic reticulum
BAFK78_RS00380	COG4591	ABC-type transport system involved in lipoprotein release permease component
BAFK78_RS00385	COG1136	(ABC) transporter
BAFK78_RS00415	COG0606	chelatase, subunit chli
BAFK78_RS00420	COG0039	L-malate dehydrogenase activity
BAFK78_RS00425	COG0481	GTPase activity
BAFK78_RS00450	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
BAFK78_RS00455	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
BAFK78_RS00465	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
BAFK78_RS00480	COG1162	GTPase activity
BAFK78_RS00490	COG0017	Asparaginyl-tRNA synthetase
BAFK78_RS00505	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BAFK78_RS00520	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BAFK78_RS00540	COG0305	Participates in initiation and elongation during chromosome replication
BAFK78_RS00545	COG0359	binds to the 23S rRNA
BAFK78_RS00550	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BAFK78_RS00560	COG0360	Binds together with S18 to 16S ribosomal RNA
BAFK78_RS00565	COG1263	PTS System
BAFK78_RS00565	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BAFK78_RS00565	COG2190	(PTS) system
BAFK78_RS00580	COG4589	Belongs to the CDS family
BAFK78_RS00595	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BAFK78_RS00600	COG0052	Belongs to the universal ribosomal protein uS2 family
BAFK78_RS00620	COG0539	negative regulation of cytoplasmic translation
BAFK78_RS00625	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BAFK78_RS00640	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BAFK78_RS00660	COG0124	histidyl-tRNA synthetase
BAFK78_RS00665	COG0768	penicillin binding
BAFK78_RS00670	COG1022	Amp-dependent synthetase and ligase
BAFK78_RS00695	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BAFK78_RS00705	COG4176	ABC-type proline glycine betaine transport system permease component
BAFK78_RS00710	COG4175	Glycine betaine
BAFK78_RS00710	COG3448	diguanylate cyclase activity
BAFK78_RS00725	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BAFK78_RS00730	COG0363	glucosamine-6-phosphate deaminase activity
BAFK78_RS00740	COG0653	protein targeting
BAFK78_RS00795	COG1640	4-alpha-glucanotransferase
BAFK78_RS00810	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BAFK78_RS00845	COG0714	Associated with various cellular activities
BAFK78_RS00850	COG0357	Ribosomal RNA small subunit methyltransferase G
BAFK78_RS00855	COG0445	tRNA wobble uridine modification
BAFK78_RS00860	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BAFK78_RS00875	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BAFK78_RS00880	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
BAFK78_RS00885	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BAFK78_RS00905	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BAFK78_RS00910	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BAFK78_RS00915	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BAFK78_RS00930	COG0084	hydrolase, TatD family'
BAFK78_RS00940	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BAFK78_RS00960	COG1181	Belongs to the D-alanine--D-alanine ligase family
BAFK78_RS00965	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BAFK78_RS00975	COG4536	flavin adenine dinucleotide binding
BAFK78_RS01005	COG0742	ribosomal rna small subunit methyltransferase
BAFK78_RS01010	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BAFK78_RS01030	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BAFK78_RS01050	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BAFK78_RS01060	COG0573	inorganic phosphate transmembrane transporter activity
BAFK78_RS01065	COG0581	inorganic phosphate transmembrane transporter activity
BAFK78_RS01070	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BAFK78_RS01080	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BAFK78_RS01085	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BAFK78_RS01095	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BAFK78_RS01100	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BAFK78_RS01115	COG0254	rRNA binding
BAFK78_RS01145	COG0012	GTP binding
BAFK78_RS01165	COG1428	Deoxynucleoside kinase
BAFK78_RS01170	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BAFK78_RS01175	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BAFK78_RS01185	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BAFK78_RS01200	COG0739	heme binding
BAFK78_RS01205	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BAFK78_RS01230	COG0495	leucyl-tRNA aminoacylation
BAFK78_RS01245	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BAFK78_RS01250	COG0739	heme binding
BAFK78_RS01265	COG1968	undecaprenyl-diphosphatase activity
BAFK78_RS01290	COG0681	Belongs to the peptidase S26 family
BAFK78_RS01295	COG0443	Heat shock 70 kDa protein
BAFK78_RS01375	COG1360	Flagellar Motor Protein
BAFK78_RS01385	COG1582	Flagellar protein (FlbD)
BAFK78_RS01395	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BAFK78_RS01455	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BAFK78_RS01480	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BAFK78_RS01490	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BAFK78_RS01505	COG0275	rRNA processing
BAFK78_RS01530	COG0835	chemotaxis
BAFK78_RS01535	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BAFK78_RS01620	COG0601	transmembrane transport
BAFK78_RS01625	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BAFK78_RS01630	COG0444	Belongs to the ABC transporter superfamily
BAFK78_RS01635	COG4608	Belongs to the ABC transporter superfamily
BAFK78_RS01645	COG0148	phosphopyruvate hydratase activity
BAFK78_RS01650	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BAFK78_RS01655	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BAFK78_RS01665	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BAFK78_RS01670	COG0154	amidase activity
BAFK78_RS01680	COG0210	DNA helicase
BAFK78_RS01710	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BAFK78_RS01750	COG0793	Belongs to the peptidase S41A family
BAFK78_RS01755	COG0455	bacterial-type flagellum organization
BAFK78_RS01760	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BAFK78_RS01770	COG1803	Methylglyoxal synthase
BAFK78_RS01780	COG1362	aminopeptidase activity
BAFK78_RS01790	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BAFK78_RS01795	COG0542	response to heat
BAFK78_RS01800	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BAFK78_RS01805	COG0423	glycine-tRNA ligase activity
BAFK78_RS01810	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BAFK78_RS01825	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BAFK78_RS01830	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BAFK78_RS01835	COG1854	S-ribosylhomocysteine lyase activity
BAFK78_RS01850	COG2239	Acts as a magnesium transporter
BAFK78_RS01860	COG1744	ABC transporter substrate-binding protein PnrA-like
BAFK78_RS01865	COG1744	ABC transporter substrate-binding protein PnrA-like
BAFK78_RS01880	COG1744	ABC transporter substrate-binding protein PnrA-like
BAFK78_RS01895	COG0049	tRNA binding
BAFK78_RS01905	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BAFK78_RS01910	COG0085	RNA polymerase activity
BAFK78_RS01915	COG0222	ribosome binding
BAFK78_RS01920	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BAFK78_RS01925	COG0081	regulation of translation
BAFK78_RS01930	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BAFK78_RS01985	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BAFK78_RS02015	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BAFK78_RS02015	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BAFK78_RS02015	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BAFK78_RS02095	COG0561	phosphatase activity
BAFK78_RS02100	COG2094	Belongs to the DNA glycosylase MPG family
BAFK78_RS02130	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BAFK78_RS02145	COG1739	Uncharacterized protein family UPF0029
BAFK78_RS02150	COG1192	Involved in chromosome partitioning
BAFK78_RS02175	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BAFK78_RS02190	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BAFK78_RS02195	COG0594	ribonuclease P activity
BAFK78_RS02200	COG0706	membrane insertase activity
BAFK78_RS02220	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BAFK78_RS02240	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BAFK78_RS02255	COG0668	transmembrane transport
BAFK78_RS02275	COG0322	excinuclease ABC activity
BAFK78_RS02315	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BAFK78_RS02320	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BAFK78_RS02340	COG1137	ATPase activity
BAFK78_RS02355	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BAFK78_RS02385	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BAFK78_RS02395	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BAFK78_RS02400	COG0088	Forms part of the polypeptide exit tunnel
BAFK78_RS02410	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BAFK78_RS02420	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BAFK78_RS02425	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BAFK78_RS02430	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BAFK78_RS02435	COG0255	Belongs to the universal ribosomal protein uL29 family
BAFK78_RS02440	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BAFK78_RS02445	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BAFK78_RS02450	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BAFK78_RS02455	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BAFK78_RS02460	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BAFK78_RS02465	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BAFK78_RS02470	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BAFK78_RS02475	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BAFK78_RS02480	COG1841	ribosomal large subunit assembly
BAFK78_RS02485	COG0200	Binds to the 23S rRNA
BAFK78_RS02495	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BAFK78_RS02500	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BAFK78_RS02510	COG0202	RNA polymerase activity
BAFK78_RS02515	COG0203	ribosomal protein L17
BAFK78_RS02520	COG1418	mRNA catabolic process
BAFK78_RS02525	COG1692	metallophosphoesterase
BAFK78_RS02530	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BAFK78_RS02540	COG1160	GTP binding
BAFK78_RS02565	COG0072	phenylalanine-tRNA ligase activity
BAFK78_RS02585	COG0443	Heat shock 70 kDa protein
BAFK78_RS02590	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BAFK78_RS02595	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BAFK78_RS02595	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BAFK78_RS02620	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BAFK78_RS02625	COG0667	Aldo Keto reductase
BAFK78_RS02645	COG0321	lipoyl(octanoyl) transferase activity
BAFK78_RS02645	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BAFK78_RS02650	COG0708	Exodeoxyribonuclease III
BAFK78_RS02660	COG0612	Peptidase, M16
BAFK78_RS02690	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BAFK78_RS02725	COG0237	dephospho-CoA kinase activity
BAFK78_RS02745	COG2201	protein-glutamate methylesterase activity
BAFK78_RS02750	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BAFK78_RS02790	COG0326	Molecular chaperone. Has ATPase activity
BAFK78_RS02795	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BAFK78_RS02825	COG0643	Histidine kinase
BAFK78_RS02825	COG2198	Histidine kinase
BAFK78_RS02840	COG0745	RESPONSE REGULATOR receiver
BAFK78_RS02850	COG0528	UMP kinase activity
BAFK78_RS02855	COG1216	Glycosyl transferase, family 2
BAFK78_RS02860	COG1131	(ABC) transporter
BAFK78_RS02870	COG0504	CTP synthase activity
BAFK78_RS02885	COG0840	transmembrane signaling receptor activity
BAFK78_RS02920	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BAFK78_RS02925	COG2348	transferase activity, transferring amino-acyl groups
BAFK78_RS02930	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BAFK78_RS02930	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BAFK78_RS02935	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BAFK78_RS02945	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BAFK78_RS02960	COG1022	Amp-dependent synthetase and ligase
BAFK78_RS02965	COG0018	arginyl-trna synthetase
BAFK78_RS02975	COG0840	transmembrane signaling receptor activity
BAFK78_RS02980	COG0840	transmembrane signaling receptor activity
BAFK78_RS02980	COG5278	phosphoserine phosphatase activity
BAFK78_RS02985	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BAFK78_RS02990	COG0215	cysteine-tRNA ligase activity
BAFK78_RS03000	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BAFK78_RS03005	COG0484	heat shock protein binding
BAFK78_RS03015	COG1620	l-lactate permease
BAFK78_RS03020	COG1686	Belongs to the peptidase S11 family
BAFK78_RS03025	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BAFK78_RS03030	COG0210	DNA helicase
BAFK78_RS03035	COG2195	Cleaves the N-terminal amino acid of tripeptides
BAFK78_RS03060	COG0544	peptidyl-prolyl cis-trans isomerase activity
BAFK78_RS03065	COG0740	serine-type endopeptidase activity
BAFK78_RS03080	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BAFK78_RS03100	COG0295	cytidine deaminase activity
BAFK78_RS03125	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BAFK78_RS03140	COG0860	N-Acetylmuramoyl-L-alanine amidase
BAFK78_RS03165	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BAFK78_RS03165	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BAFK78_RS03165	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BAFK78_RS03185	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BAFK78_RS03200	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BAFK78_RS03225	COG1177	transmembrane transport
BAFK78_RS03230	COG1176	ABC-type spermidine putrescine transport system, permease component I
BAFK78_RS03235	COG3842	ATPase activity
BAFK78_RS03240	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BAFK78_RS03245	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
BAFK78_RS03270	COG0459	protein refolding
BAFK78_RS03300	COG0484	heat shock protein binding
BAFK78_RS03310	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BAFK78_RS03315	COG0588	phosphoglycerate mutase activity
BAFK78_RS03325	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BAFK78_RS03355	COG0860	N-Acetylmuramoyl-L-alanine amidase
BAFK78_RS03375	COG0835	chemotaxis
BAFK78_RS03385	COG2201	protein-glutamate methylesterase activity
BAFK78_RS03410	COG3845	ABC transporter
BAFK78_RS03415	COG4603	Belongs to the binding-protein-dependent transport system permease family
BAFK78_RS03420	COG1079	Belongs to the binding-protein-dependent transport system permease family
BAFK78_RS03435	COG0482	sulfurtransferase activity
BAFK78_RS03440	COG3425	synthase
BAFK78_RS03445	COG1304	FMN binding
BAFK78_RS03480	COG0783	Belongs to the Dps family
BAFK78_RS03485	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BAFK78_RS03495	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BAFK78_RS03510	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BAFK78_RS03515	COG0336	Belongs to the RNA methyltransferase TrmD family
BAFK78_RS03520	COG0335	large ribosomal subunit rRNA binding
BAFK78_RS03530	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BAFK78_RS03540	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BAFK78_RS03545	COG0571	ribonuclease III activity
BAFK78_RS03550	COG0617	tRNA 3'-terminal CCA addition
BAFK78_RS03575	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BAFK78_RS03600	COG1077	Cell shape determining protein MreB Mrl
BAFK78_RS03615	COG0768	penicillin binding
BAFK78_RS03620	COG0772	Belongs to the SEDS family
BAFK78_RS03625	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BAFK78_RS03630	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BAFK78_RS03645	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BAFK78_RS03655	COG0003	Pfam Anion-transporting ATPase
BAFK78_RS03665	COG0446	pyridine nucleotide-disulphide oxidoreductase
BAFK78_RS03675	COG0166	Belongs to the GPI family
BAFK78_RS03680	COG1475	DNA binding
BAFK78_RS03695	COG0009	L-threonylcarbamoyladenylate synthase
BAFK78_RS03700	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BAFK78_RS03710	COG0525	valine-tRNA ligase activity
BAFK78_RS03725	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BAFK78_RS03730	COG0488	(ABC) transporter
BAFK78_RS03755	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BAFK78_RS03760	COG4239	(ABC) transporter, permease
BAFK78_RS03765	COG4168	peptide transport system, permease
BAFK78_RS03795	COG1131	(ABC) transporter
BAFK78_RS03800	COG1234	tRNA 3'-trailer cleavage
BAFK78_RS03805	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BAFK78_RS03835	COG0739	heme binding
BAFK78_RS03840	COG2204	response regulator
BAFK78_RS03845	COG5002	protein histidine kinase activity
BAFK78_RS03850	COG0470	DNA polymerase III
BAFK78_RS03860	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BAFK78_RS03870	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BAFK78_RS03880	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BAFK78_RS03905	COG4786	Flagellar basal body rod
BAFK78_RS03915	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BAFK78_RS03920	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BAFK78_RS03935	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BAFK78_RS03940	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BAFK78_RS03955	COG2088	sporulation resulting in formation of a cellular spore
BAFK78_RS03965	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BAFK78_RS03970	COG0193	aminoacyl-tRNA hydrolase activity
BAFK78_RS03975	COG0037	tRNA processing
BAFK78_RS04000	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BAFK78_RS04010	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BAFK78_RS04020	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BAFK78_RS04025	COG1040	competence protein
BAFK78_RS04030	COG0779	Required for maturation of 30S ribosomal subunits
BAFK78_RS04040	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BAFK78_RS04045	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BAFK78_RS04050	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BAFK78_RS04055	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BAFK78_RS04060	COG1185	polyribonucleotide nucleotidyltransferase activity
BAFK78_RS04080	COG0343	queuine tRNA-ribosyltransferase activity
BAFK78_RS04100	COG4145	pantothenate transmembrane transporter activity
BAFK78_RS04105	COG0564	pseudouridine synthase activity
BAFK78_RS04115	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BAFK78_RS04120	COG1561	YicC-like family, N-terminal region
BAFK78_RS04125	COG1102	Psort location Cytoplasmic, score
BAFK78_RS04135	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BAFK78_RS04175	COG0419	ATPase involved in DNA repair
BAFK78_RS04180	COG1940	carbohydrate kinase activity
BAFK78_RS04190	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BAFK78_RS04200	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BAFK78_RS04205	COG0556	nucleotide-excision repair
BAFK78_RS04235	COG2235	arginine
BAFK78_RS04245	COG1288	antiporter activity
BAFK78_RS04520	COG1196	nuclear chromosome segregation
BAFK78_RS04645	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BAFK78_RS05070	COG2255	four-way junction helicase activity
BAFK78_RS05165	COG0101	tRNA pseudouridine synthase activity
BAFK78_RS05235	COG0101	tRNA pseudouridine synthase activity
BAFK78_RS05265	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BAFK78_RS05280	COG0217	transcriptional regulatory protein
BAFK78_RS05425	COG1472	Belongs to the glycosyl hydrolase 3 family
BAFK78_RS05705	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BAFK78_RS06120	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BAFK78_RS06330	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284