locus-tag	class	description
BDU_RS00045	COG1472	Belongs to the glycosyl hydrolase 3 family
BDU_RS00055	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BDU_RS00075	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BDU_RS00085	COG0736	holo-[acyl-carrier-protein] synthase activity
BDU_RS00095	COG0101	tRNA pseudouridine synthase activity
BDU_RS00110	COG0572	uridine kinase
BDU_RS00120	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BDU_RS00140	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BDU_RS00150	COG0632	four-way junction helicase activity
BDU_RS00155	COG0217	transcriptional regulatory protein
BDU_RS00160	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BDU_RS00185	COG0681	Belongs to the peptidase S26 family
BDU_RS00255	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BDU_RS00270	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BDU_RS00280	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BDU_RS00290	COG0149	triose-phosphate isomerase activity
BDU_RS00295	COG0126	phosphoglycerate kinase activity
BDU_RS00315	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BDU_RS00335	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BDU_RS00350	COG0006	proline dipeptidase activity
BDU_RS00355	COG0561	phosphatase activity
BDU_RS00360	COG2309	aminopeptidase activity
BDU_RS00395	COG0552	protein localization to endoplasmic reticulum
BDU_RS00405	COG4591	ABC-type transport system involved in lipoprotein release permease component
BDU_RS00410	COG1136	(ABC) transporter
BDU_RS00440	COG0606	chelatase, subunit chli
BDU_RS00480	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
BDU_RS00490	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
BDU_RS00505	COG1162	GTPase activity
BDU_RS00530	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BDU_RS00545	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BDU_RS00550	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BDU_RS00555	COG0183	Belongs to the thiolase family
BDU_RS00565	COG0305	Participates in initiation and elongation during chromosome replication
BDU_RS00570	COG0359	binds to the 23S rRNA
BDU_RS00575	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BDU_RS00585	COG0360	Binds together with S18 to 16S ribosomal RNA
BDU_RS00590	COG1263	PTS System
BDU_RS00590	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BDU_RS00590	COG2190	(PTS) system
BDU_RS00605	COG4589	Belongs to the CDS family
BDU_RS00615	COG0233	cytoplasmic translational termination
BDU_RS00620	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BDU_RS00625	COG0052	Belongs to the universal ribosomal protein uS2 family
BDU_RS00630	COG0424	maF-like protein
BDU_RS00650	COG0539	negative regulation of cytoplasmic translation
BDU_RS00655	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BDU_RS00670	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BDU_RS00700	COG1022	Amp-dependent synthetase and ligase
BDU_RS00735	COG4176	ABC-type proline glycine betaine transport system permease component
BDU_RS00740	COG4175	Glycine betaine
BDU_RS00740	COG0517	IMP dehydrogenase activity
BDU_RS00755	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BDU_RS00805	COG0530	calcium, potassium:sodium antiporter activity
BDU_RS00815	COG1640	4-alpha-glucanotransferase
BDU_RS00865	COG0714	Associated with various cellular activities
BDU_RS00870	COG0357	Ribosomal RNA small subunit methyltransferase G
BDU_RS00875	COG0445	tRNA wobble uridine modification
BDU_RS00880	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BDU_RS00900	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
BDU_RS00905	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BDU_RS00925	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BDU_RS00930	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BDU_RS00935	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BDU_RS00945	COG0084	hydrolase, TatD family'
BDU_RS00975	COG1181	Belongs to the D-alanine--D-alanine ligase family
BDU_RS00980	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BDU_RS00990	COG4536	flavin adenine dinucleotide binding
BDU_RS01045	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BDU_RS01065	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BDU_RS01075	COG0573	inorganic phosphate transmembrane transporter activity
BDU_RS01080	COG0581	inorganic phosphate transmembrane transporter activity
BDU_RS01085	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BDU_RS01100	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BDU_RS01115	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BDU_RS01120	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BDU_RS01155	COG0268	Binds directly to 16S ribosomal RNA
BDU_RS01165	COG0012	GTP binding
BDU_RS01185	COG1428	Deoxynucleoside kinase
BDU_RS01195	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BDU_RS01200	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BDU_RS01205	COG2271	Major facilitator Superfamily
BDU_RS01210	COG0584	glycerophosphoryl diester phosphodiesterase
BDU_RS01230	COG0739	heme binding
BDU_RS01235	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BDU_RS01260	COG0495	leucyl-tRNA aminoacylation
BDU_RS01270	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BDU_RS01280	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BDU_RS01285	COG0739	heme binding
BDU_RS01300	COG1968	undecaprenyl-diphosphatase activity
BDU_RS01305	COG0739	heme binding
BDU_RS01305	COG0741	lytic transglycosylase activity
BDU_RS01305	COG1196	nuclear chromosome segregation
BDU_RS01320	COG1196	nuclear chromosome segregation
BDU_RS01320	COG0739	heme binding
BDU_RS01320	COG0741	lytic transglycosylase activity
BDU_RS01330	COG0443	Heat shock 70 kDa protein
BDU_RS01410	COG1360	Flagellar Motor Protein
BDU_RS01430	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BDU_RS01480	COG1815	bacterial-type flagellum-dependent cell motility
BDU_RS01490	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BDU_RS01515	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BDU_RS01525	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BDU_RS01540	COG0275	rRNA processing
BDU_RS01570	COG0835	chemotaxis
BDU_RS01575	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BDU_RS01580	COG0142	geranyltranstransferase activity
BDU_RS01650	COG0601	transmembrane transport
BDU_RS01655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BDU_RS01660	COG0444	Belongs to the ABC transporter superfamily
BDU_RS01665	COG4608	Belongs to the ABC transporter superfamily
BDU_RS01675	COG0148	phosphopyruvate hydratase activity
BDU_RS01680	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BDU_RS01685	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BDU_RS01695	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BDU_RS01700	COG0154	amidase activity
BDU_RS01725	COG1293	RNA-binding protein homologous to eukaryotic snRNP
BDU_RS01735	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BDU_RS01775	COG0793	Belongs to the peptidase S41A family
BDU_RS01780	COG0455	bacterial-type flagellum organization
BDU_RS01785	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BDU_RS01805	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BDU_RS01810	COG0542	response to heat
BDU_RS01810	COG0542	response to heat
BDU_RS01815	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BDU_RS01825	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BDU_RS01840	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BDU_RS01845	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BDU_RS01850	COG1854	S-ribosylhomocysteine lyase activity
BDU_RS01860	COG2239	Acts as a magnesium transporter
BDU_RS01870	COG1744	ABC transporter substrate-binding protein PnrA-like
BDU_RS01890	COG0049	tRNA binding
BDU_RS01895	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BDU_RS01900	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BDU_RS01905	COG0085	RNA polymerase activity
BDU_RS01910	COG0222	ribosome binding
BDU_RS01915	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BDU_RS01920	COG0081	regulation of translation
BDU_RS01925	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BDU_RS01945	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BDU_RS02000	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BDU_RS02000	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BDU_RS02000	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BDU_RS02020	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BDU_RS02040	COG0563	adenylate kinase activity
BDU_RS02050	COG5001	Diguanylate cyclase
BDU_RS02050	COG2203	Gaf domain
BDU_RS02050	COG3706	GGDEF domain
BDU_RS02050	COG4251	negative regulation of phosphorylation
BDU_RS02070	COG0561	phosphatase activity
BDU_RS02080	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BDU_RS02085	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BDU_RS02110	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BDU_RS02130	COG1192	Involved in chromosome partitioning
BDU_RS02150	COG0187	DNA topoisomerase II activity
BDU_RS02155	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BDU_RS02165	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BDU_RS02175	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BDU_RS02180	COG0594	ribonuclease P activity
BDU_RS02185	COG0706	membrane insertase activity
BDU_RS02205	COG0071	Belongs to the small heat shock protein (HSP20) family
BDU_RS02210	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BDU_RS02215	COG0475	glutathione-regulated potassium exporter activity
BDU_RS02230	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BDU_RS02235	COG2059	Chromate
BDU_RS02245	COG0668	transmembrane transport
BDU_RS02260	COG0322	excinuclease ABC activity
BDU_RS02300	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BDU_RS02305	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BDU_RS02310	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BDU_RS02335	COG1137	ATPase activity
BDU_RS02350	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BDU_RS02365	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BDU_RS02370	COG0534	Mate efflux family protein
BDU_RS02380	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BDU_RS02385	COG0051	transcription antitermination factor activity, RNA binding
BDU_RS02390	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BDU_RS02395	COG0088	Forms part of the polypeptide exit tunnel
BDU_RS02405	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BDU_RS02410	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BDU_RS02415	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BDU_RS02420	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BDU_RS02425	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BDU_RS02430	COG0255	Belongs to the universal ribosomal protein uL29 family
BDU_RS02435	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BDU_RS02440	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BDU_RS02445	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BDU_RS02450	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BDU_RS02455	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BDU_RS02460	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BDU_RS02465	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BDU_RS02470	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BDU_RS02495	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BDU_RS02500	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BDU_RS02510	COG0202	RNA polymerase activity
BDU_RS02515	COG0203	ribosomal protein L17
BDU_RS02525	COG1692	metallophosphoesterase
BDU_RS02540	COG1160	GTP binding
BDU_RS02565	COG0072	phenylalanine-tRNA ligase activity
BDU_RS02585	COG0443	Heat shock 70 kDa protein
BDU_RS02595	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BDU_RS02595	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BDU_RS02635	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BDU_RS02635	COG0321	lipoyl(octanoyl) transferase activity
BDU_RS02640	COG0708	Exodeoxyribonuclease III
BDU_RS02650	COG0612	Peptidase, M16
BDU_RS02750	COG2201	protein-glutamate methylesterase activity
BDU_RS02755	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BDU_RS02795	COG0326	Molecular chaperone. Has ATPase activity
BDU_RS02800	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BDU_RS02820	COG0835	chemotaxis
BDU_RS02830	COG0643	Histidine kinase
BDU_RS02830	COG2198	Histidine kinase
BDU_RS02850	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BDU_RS02860	COG0528	UMP kinase activity
BDU_RS02865	COG1216	Glycosyl transferase, family 2
BDU_RS02870	COG4555	ABC transporter
BDU_RS02880	COG0504	CTP synthase activity
BDU_RS02890	COG0840	transmembrane signaling receptor activity
BDU_RS02930	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BDU_RS02930	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BDU_RS02940	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BDU_RS02955	COG1022	Amp-dependent synthetase and ligase
BDU_RS02960	COG0018	arginyl-trna synthetase
BDU_RS02970	COG0840	transmembrane signaling receptor activity
BDU_RS02975	COG5278	phosphoserine phosphatase activity
BDU_RS02975	COG0840	transmembrane signaling receptor activity
BDU_RS02980	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BDU_RS02995	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BDU_RS03000	COG0484	heat shock protein binding
BDU_RS03010	COG1620	l-lactate permease
BDU_RS03015	COG1686	Belongs to the peptidase S11 family
BDU_RS03020	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BDU_RS03025	COG2195	Cleaves the N-terminal amino acid of tripeptides
BDU_RS03050	COG0544	peptidyl-prolyl cis-trans isomerase activity
BDU_RS03055	COG0740	serine-type endopeptidase activity
BDU_RS03060	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BDU_RS03070	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BDU_RS03110	COG0693	protein deglycase activity
BDU_RS03115	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BDU_RS03130	COG3584	3D domain protein
BDU_RS03130	COG1388	LysM domain
BDU_RS03150	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BDU_RS03150	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BDU_RS03150	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BDU_RS03165	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BDU_RS03175	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BDU_RS03180	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BDU_RS03190	COG1757	Na H antiporter
BDU_RS03200	COG1177	transmembrane transport
BDU_RS03215	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BDU_RS03220	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
BDU_RS03225	COG2190	(PTS) system
BDU_RS03225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BDU_RS03225	COG1263	PTS System
BDU_RS03245	COG0459	protein refolding
BDU_RS03275	COG0484	heat shock protein binding
BDU_RS03290	COG0588	phosphoglycerate mutase activity
BDU_RS03300	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BDU_RS03330	COG0860	N-Acetylmuramoyl-L-alanine amidase
BDU_RS03350	COG0835	chemotaxis
BDU_RS03360	COG2201	protein-glutamate methylesterase activity
BDU_RS03380	COG0546	phosphoglycolate phosphatase activity
BDU_RS03385	COG3845	ABC transporter
BDU_RS03390	COG4603	Belongs to the binding-protein-dependent transport system permease family
BDU_RS03395	COG1079	Belongs to the binding-protein-dependent transport system permease family
BDU_RS03405	COG0840	transmembrane signaling receptor activity
BDU_RS03410	COG0482	sulfurtransferase activity
BDU_RS03415	COG3425	synthase
BDU_RS03420	COG1304	FMN binding
BDU_RS03460	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BDU_RS03470	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BDU_RS03475	COG0228	four-way junction DNA binding
BDU_RS03490	COG0336	Belongs to the RNA methyltransferase TrmD family
BDU_RS03495	COG0335	large ribosomal subunit rRNA binding
BDU_RS03505	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BDU_RS03510	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BDU_RS03515	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BDU_RS03520	COG0571	ribonuclease III activity
BDU_RS03525	COG0617	tRNA 3'-terminal CCA addition
BDU_RS03550	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BDU_RS03575	COG1077	Cell shape determining protein MreB Mrl
BDU_RS03590	COG0768	penicillin binding
BDU_RS03595	COG0772	Belongs to the SEDS family
BDU_RS03600	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BDU_RS03620	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BDU_RS03630	COG0489	protein tyrosine kinase activity
BDU_RS03640	COG0446	pyridine nucleotide-disulphide oxidoreductase
BDU_RS03655	COG1475	DNA binding
BDU_RS03675	COG0009	L-threonylcarbamoyladenylate synthase
BDU_RS03680	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BDU_RS03685	COG1199	ATP-dependent helicase activity
BDU_RS03690	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BDU_RS03700	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BDU_RS03700	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
BDU_RS03705	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BDU_RS03710	COG0488	(ABC) transporter
BDU_RS03735	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BDU_RS03740	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BDU_RS03745	COG0601	transmembrane transport
BDU_RS03780	COG1131	(ABC) transporter
BDU_RS03785	COG1234	tRNA 3'-trailer cleavage
BDU_RS03790	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BDU_RS03790	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BDU_RS03820	COG0739	heme binding
BDU_RS03825	COG2204	response regulator
BDU_RS03830	COG3852	Histidine kinase
BDU_RS03835	COG0470	DNA polymerase III
BDU_RS03855	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BDU_RS03865	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BDU_RS03890	COG4786	Flagellar basal body rod
BDU_RS03900	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BDU_RS03905	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BDU_RS03915	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BDU_RS03920	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BDU_RS03935	COG0799	negative regulation of ribosome biogenesis
BDU_RS03940	COG2088	sporulation resulting in formation of a cellular spore
BDU_RS03950	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BDU_RS03955	COG0193	aminoacyl-tRNA hydrolase activity
BDU_RS03960	COG0037	tRNA processing
BDU_RS03975	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BDU_RS03990	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BDU_RS04000	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BDU_RS04015	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BDU_RS04025	COG0779	Required for maturation of 30S ribosomal subunits
BDU_RS04055	COG1185	polyribonucleotide nucleotidyltransferase activity
BDU_RS04075	COG0343	queuine tRNA-ribosyltransferase activity
BDU_RS04095	COG4145	pantothenate transmembrane transporter activity
BDU_RS04120	COG4145	pantothenate transmembrane transporter activity
BDU_RS04145	COG1102	Psort location Cytoplasmic, score
BDU_RS04155	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BDU_RS04180	COG1263	PTS System
BDU_RS04180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BDU_RS04180	COG2190	(PTS) system
BDU_RS04210	COG3142	Participates in the control of copper homeostasis
BDU_RS04220	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BDU_RS04230	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BDU_RS04260	COG2235	arginine
BDU_RS04270	COG1288	antiporter activity
BDU_RS04275	COG0549	Belongs to the carbamate kinase family
BDU_RS04280	COG2252	PERMEase
BDU_RS04650	COG1196	nuclear chromosome segregation
BDU_RS04655	COG1196	nuclear chromosome segregation
BDU_RS04895	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
BDU_RS05210	COG1472	Belongs to the glycosyl hydrolase 3 family
BDU_RS05860	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BDU_RS06670	COG1472	Belongs to the glycosyl hydrolase 3 family
BDU_RS06985	COG0632	four-way junction helicase activity
BDU_RS07285	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284