locus-tag	class	description
BHT49_RS00015	COG1472	Belongs to the glycosyl hydrolase 3 family
BHT49_RS00025	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BHT49_RS00090	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BHT49_RS00160	COG0681	Belongs to the peptidase S26 family
BHT49_RS00225	COG1196	nuclear chromosome segregation
BHT49_RS00250	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BHT49_RS00340	COG0561	phosphatase activity
BHT49_RS00345	COG2309	aminopeptidase activity
BHT49_RS00350	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BHT49_RS00380	COG0552	protein localization to endoplasmic reticulum
BHT49_RS00390	COG4591	ABC-type transport system involved in lipoprotein release permease component
BHT49_RS00395	COG1136	(ABC) transporter
BHT49_RS00425	COG0606	chelatase, subunit chli
BHT49_RS00515	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BHT49_RS00550	COG0305	Participates in initiation and elongation during chromosome replication
BHT49_RS00575	COG1263	PTS System
BHT49_RS00575	COG2190	(PTS) system
BHT49_RS00575	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BHT49_RS00590	COG4589	Belongs to the CDS family
BHT49_RS00630	COG0539	negative regulation of cytoplasmic translation
BHT49_RS00675	COG0768	penicillin binding
BHT49_RS00680	COG1022	Amp-dependent synthetase and ligase
BHT49_RS00720	COG4176	ABC-type proline glycine betaine transport system permease component
BHT49_RS00725	COG3448	diguanylate cyclase activity
BHT49_RS00725	COG4175	Glycine betaine
BHT49_RS00740	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BHT49_RS00865	COG0714	Associated with various cellular activities
BHT49_RS00910	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BHT49_RS00950	COG0084	hydrolase, TatD family'
BHT49_RS00995	COG4536	flavin adenine dinucleotide binding
BHT49_RS01025	COG0742	ribosomal rna small subunit methyltransferase
BHT49_RS01030	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BHT49_RS01080	COG0573	inorganic phosphate transmembrane transporter activity
BHT49_RS01085	COG0581	inorganic phosphate transmembrane transporter activity
BHT49_RS01105	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BHT49_RS01125	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BHT49_RS01175	COG0012	GTP binding
BHT49_RS01195	COG1428	Deoxynucleoside kinase
BHT49_RS01200	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BHT49_RS01215	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BHT49_RS01230	COG0739	heme binding
BHT49_RS01275	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BHT49_RS01280	COG0739	heme binding
BHT49_RS01320	COG0681	Belongs to the peptidase S26 family
BHT49_RS01325	COG0443	Heat shock 70 kDa protein
BHT49_RS01405	COG1360	Flagellar Motor Protein
BHT49_RS01415	COG1582	Flagellar protein (FlbD)
BHT49_RS01425	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BHT49_RS01510	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BHT49_RS01560	COG0835	chemotaxis
BHT49_RS01655	COG0601	transmembrane transport
BHT49_RS01660	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BHT49_RS01665	COG0444	Belongs to the ABC transporter superfamily
BHT49_RS01670	COG4608	Belongs to the ABC transporter superfamily
BHT49_RS01785	COG0793	Belongs to the peptidase S41A family
BHT49_RS01795	COG0455	bacterial-type flagellum organization
BHT49_RS01830	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BHT49_RS01835	COG0542	response to heat
BHT49_RS01865	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BHT49_RS01890	COG2239	Acts as a magnesium transporter
BHT49_RS02040	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BHT49_RS02040	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BHT49_RS02040	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BHT49_RS02120	COG0561	phosphatase activity
BHT49_RS02150	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BHT49_RS02165	COG1739	Uncharacterized protein family UPF0029
BHT49_RS02170	COG1192	Involved in chromosome partitioning
BHT49_RS02265	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BHT49_RS02280	COG0668	transmembrane transport
BHT49_RS02345	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BHT49_RS02370	COG1137	ATPase activity
BHT49_RS02530	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BHT49_RS02560	COG1692	metallophosphoesterase
BHT49_RS02565	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BHT49_RS02630	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BHT49_RS02630	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BHT49_RS02655	COG0667	Aldo Keto reductase
BHT49_RS02675	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BHT49_RS02675	COG0321	lipoyl(octanoyl) transferase activity
BHT49_RS02680	COG0708	Exodeoxyribonuclease III
BHT49_RS02690	COG0612	Peptidase, M16
BHT49_RS02775	COG2201	protein-glutamate methylesterase activity
BHT49_RS02825	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BHT49_RS02845	COG0835	chemotaxis
BHT49_RS02855	COG2198	Histidine kinase
BHT49_RS02855	COG0643	Histidine kinase
BHT49_RS02870	COG0745	RESPONSE REGULATOR receiver
BHT49_RS02880	COG0528	UMP kinase activity
BHT49_RS02885	COG1216	Glycosyl transferase, family 2
BHT49_RS02890	COG1131	(ABC) transporter
BHT49_RS02915	COG0840	transmembrane signaling receptor activity
BHT49_RS02915	COG3290	protein histidine kinase activity
BHT49_RS02940	COG0534	Mate efflux family protein
BHT49_RS02960	COG2348	transferase activity, transferring amino-acyl groups
BHT49_RS02970	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BHT49_RS02985	COG2333	competence protein COMEC
BHT49_RS02985	COG0658	competence protein
BHT49_RS02995	COG1022	Amp-dependent synthetase and ligase
BHT49_RS03010	COG0840	transmembrane signaling receptor activity
BHT49_RS03015	COG0840	transmembrane signaling receptor activity
BHT49_RS03015	COG5278	phosphoserine phosphatase activity
BHT49_RS03040	COG0484	heat shock protein binding
BHT49_RS03050	COG1620	l-lactate permease
BHT49_RS03055	COG1686	Belongs to the peptidase S11 family
BHT49_RS03065	COG0210	DNA helicase
BHT49_RS03070	COG2195	Cleaves the N-terminal amino acid of tripeptides
BHT49_RS03140	COG0295	cytidine deaminase activity
BHT49_RS03180	COG0791	NLP P60 protein
BHT49_RS03180	COG1388	LysM domain
BHT49_RS03180	COG3103	Sh3 type 3 domain protein
BHT49_RS03205	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BHT49_RS03205	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BHT49_RS03205	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BHT49_RS03225	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BHT49_RS03240	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BHT49_RS03255	COG1757	Na H antiporter
BHT49_RS03265	COG1177	transmembrane transport
BHT49_RS03270	COG1176	ABC-type spermidine putrescine transport system, permease component I
BHT49_RS03280	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BHT49_RS03290	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BHT49_RS03290	COG1263	PTS System
BHT49_RS03290	COG2190	(PTS) system
BHT49_RS03340	COG0484	heat shock protein binding
BHT49_RS03345	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BHT49_RS03395	COG0860	N-Acetylmuramoyl-L-alanine amidase
BHT49_RS03415	COG0835	chemotaxis
BHT49_RS03425	COG2201	protein-glutamate methylesterase activity
BHT49_RS03450	COG3845	ABC transporter
BHT49_RS03455	COG4603	Belongs to the binding-protein-dependent transport system permease family
BHT49_RS03460	COG1079	Belongs to the binding-protein-dependent transport system permease family
BHT49_RS03465	COG0840	transmembrane signaling receptor activity
BHT49_RS03470	COG0840	transmembrane signaling receptor activity
BHT49_RS03480	COG3425	synthase
BHT49_RS03520	COG0783	Belongs to the Dps family
BHT49_RS03535	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BHT49_RS03590	COG0617	tRNA 3'-terminal CCA addition
BHT49_RS03615	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BHT49_RS03645	COG1077	Cell shape determining protein MreB Mrl
BHT49_RS03660	COG0768	penicillin binding
BHT49_RS03665	COG0772	Belongs to the SEDS family
BHT49_RS03675	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BHT49_RS03690	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BHT49_RS03700	COG0003	Pfam Anion-transporting ATPase
BHT49_RS03710	COG0446	pyridine nucleotide-disulphide oxidoreductase
BHT49_RS03725	COG1475	DNA binding
BHT49_RS03740	COG0009	L-threonylcarbamoyladenylate synthase
BHT49_RS03745	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BHT49_RS03765	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BHT49_RS03765	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
BHT49_RS03775	COG0488	(ABC) transporter
BHT49_RS03800	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BHT49_RS03805	COG4239	(ABC) transporter, permease
BHT49_RS03810	COG4168	peptide transport system, permease
BHT49_RS03840	COG1131	(ABC) transporter
BHT49_RS03850	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BHT49_RS03880	COG0739	heme binding
BHT49_RS03885	COG2204	response regulator
BHT49_RS03890	COG5002	protein histidine kinase activity
BHT49_RS03895	COG0470	DNA polymerase III
BHT49_RS03925	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BHT49_RS04045	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BHT49_RS04055	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BHT49_RS04070	COG1040	competence protein
BHT49_RS04145	COG4145	pantothenate transmembrane transporter activity
BHT49_RS04150	COG0564	pseudouridine synthase activity
BHT49_RS04165	COG1561	YicC-like family, N-terminal region
BHT49_RS04220	COG0419	ATPase involved in DNA repair
BHT49_RS04225	COG1940	carbohydrate kinase activity
BHT49_RS04245	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BHT49_RS04290	COG1288	antiporter activity
BHT49_RS04310	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BHT49_RS04315	COG1447	Phosphotransferase system cellobiose-specific component IIA
BHT49_RS04320	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BHT49_RS04385	COG2252	PERMEase
BHT49_RS04390	COG2252	PERMEase
BHT49_RS04420	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BHT49_RS04420	COG1263	PTS System
BHT49_RS04420	COG2190	(PTS) system
BHT49_RS04580	COG1192	Involved in chromosome partitioning
BHT49_RS04790	COG1192	Involved in chromosome partitioning
BHT49_RS05205	COG1192	Involved in chromosome partitioning
BHT49_RS05340	COG1192	Involved in chromosome partitioning
BHT49_RS05755	COG1192	Involved in chromosome partitioning
BHT49_RS05955	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BHT49_RS06000	COG1335	isochorismatase
BHT49_RS06110	COG1192	Involved in chromosome partitioning
BHT49_RS06250	COG1192	Involved in chromosome partitioning
BHT49_RS06270	COG0305	Participates in initiation and elongation during chromosome replication
BHT49_RS06425	COG1192	Involved in chromosome partitioning
BHT49_RS06510	COG1192	Involved in chromosome partitioning
BHT49_RS06690	COG1192	Involved in chromosome partitioning
BHT49_RS06735	COG1136	(ABC) transporter
BHT49_RS07025	COG4166	transmembrane transport
BHT49_RS07070	COG1192	Involved in chromosome partitioning
BHT49_RS07305	COG0305	Participates in initiation and elongation during chromosome replication