locus-tag	class	description
BbuMM1_RS00375	COG1192	Involved in chromosome partitioning
BbuMM1_RS00425	COG4166	transmembrane transport
BbuMM1_RS00640	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BbuMM1_RS00645	COG1447	Phosphotransferase system cellobiose-specific component IIA
BbuMM1_RS00650	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BbuMM1_RS00715	COG2252	PERMEase
BbuMM1_RS00720	COG2252	PERMEase
BbuMM1_RS00750	COG2190	(PTS) system
BbuMM1_RS00750	COG1263	PTS System
BbuMM1_RS00750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BbuMM1_RS00960	COG1335	isochorismatase
BbuMM1_RS01095	COG1192	Involved in chromosome partitioning
BbuMM1_RS01155	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BbuMM1_RS01335	COG1192	Involved in chromosome partitioning
BbuMM1_RS01425	COG0305	Participates in initiation and elongation during chromosome replication
BbuMM1_RS01840	COG1192	Involved in chromosome partitioning
BbuMM1_RS01980	COG1192	Involved in chromosome partitioning
BbuMM1_RS02205	COG1192	Involved in chromosome partitioning
BbuMM1_RS02320	COG1192	Involved in chromosome partitioning
BbuMM1_RS02355	COG2314	TM2 domain
BbuMM1_RS02400	COG1472	Belongs to the glycosyl hydrolase 3 family
BbuMM1_RS02410	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BbuMM1_RS02475	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BbuMM1_RS02545	COG0681	Belongs to the peptidase S26 family
BbuMM1_RS02610	COG1196	nuclear chromosome segregation
BbuMM1_RS02635	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BbuMM1_RS02725	COG0561	phosphatase activity
BbuMM1_RS02730	COG2309	aminopeptidase activity
BbuMM1_RS02735	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BbuMM1_RS02765	COG0552	protein localization to endoplasmic reticulum
BbuMM1_RS02775	COG4591	ABC-type transport system involved in lipoprotein release permease component
BbuMM1_RS02780	COG1136	(ABC) transporter
BbuMM1_RS02810	COG0606	chelatase, subunit chli
BbuMM1_RS02900	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BbuMM1_RS02935	COG0305	Participates in initiation and elongation during chromosome replication
BbuMM1_RS02960	COG1263	PTS System
BbuMM1_RS02960	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BbuMM1_RS02960	COG2190	(PTS) system
BbuMM1_RS02975	COG4589	Belongs to the CDS family
BbuMM1_RS03015	COG0539	negative regulation of cytoplasmic translation
BbuMM1_RS03060	COG0768	penicillin binding
BbuMM1_RS03065	COG1022	Amp-dependent synthetase and ligase
BbuMM1_RS03105	COG4176	ABC-type proline glycine betaine transport system permease component
BbuMM1_RS03110	COG3448	diguanylate cyclase activity
BbuMM1_RS03110	COG4175	Glycine betaine
BbuMM1_RS03125	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BbuMM1_RS03250	COG0714	Associated with various cellular activities
BbuMM1_RS03295	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BbuMM1_RS03335	COG0084	hydrolase, TatD family'
BbuMM1_RS03380	COG4536	flavin adenine dinucleotide binding
BbuMM1_RS03410	COG0742	ribosomal rna small subunit methyltransferase
BbuMM1_RS03415	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BbuMM1_RS03465	COG0573	inorganic phosphate transmembrane transporter activity
BbuMM1_RS03470	COG0581	inorganic phosphate transmembrane transporter activity
BbuMM1_RS03490	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BbuMM1_RS03510	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BbuMM1_RS03560	COG0012	GTP binding
BbuMM1_RS03580	COG1428	Deoxynucleoside kinase
BbuMM1_RS03585	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BbuMM1_RS03600	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BbuMM1_RS03615	COG0739	heme binding
BbuMM1_RS03660	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BbuMM1_RS03665	COG0739	heme binding
BbuMM1_RS03705	COG0681	Belongs to the peptidase S26 family
BbuMM1_RS03710	COG0443	Heat shock 70 kDa protein
BbuMM1_RS03790	COG1360	Flagellar Motor Protein
BbuMM1_RS03800	COG1582	Flagellar protein (FlbD)
BbuMM1_RS03810	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BbuMM1_RS03895	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BbuMM1_RS03945	COG0835	chemotaxis
BbuMM1_RS04040	COG0601	transmembrane transport
BbuMM1_RS04045	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BbuMM1_RS04050	COG0444	Belongs to the ABC transporter superfamily
BbuMM1_RS04055	COG4608	Belongs to the ABC transporter superfamily
BbuMM1_RS04100	COG0210	DNA helicase
BbuMM1_RS04170	COG0793	Belongs to the peptidase S41A family
BbuMM1_RS04180	COG0455	bacterial-type flagellum organization
BbuMM1_RS04215	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BbuMM1_RS04220	COG0542	response to heat
BbuMM1_RS04250	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BbuMM1_RS04275	COG2239	Acts as a magnesium transporter
BbuMM1_RS04425	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BbuMM1_RS04425	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BbuMM1_RS04425	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BbuMM1_RS04505	COG0561	phosphatase activity
BbuMM1_RS04535	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BbuMM1_RS04550	COG1739	Uncharacterized protein family UPF0029
BbuMM1_RS04555	COG1192	Involved in chromosome partitioning
BbuMM1_RS04650	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BbuMM1_RS04665	COG0668	transmembrane transport
BbuMM1_RS04730	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BbuMM1_RS04755	COG1137	ATPase activity
BbuMM1_RS04915	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BbuMM1_RS04945	COG1692	metallophosphoesterase
BbuMM1_RS04950	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BbuMM1_RS05015	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BbuMM1_RS05015	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BbuMM1_RS05040	COG0667	Aldo Keto reductase
BbuMM1_RS05060	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BbuMM1_RS05060	COG0321	lipoyl(octanoyl) transferase activity
BbuMM1_RS05065	COG0708	Exodeoxyribonuclease III
BbuMM1_RS05075	COG0612	Peptidase, M16
BbuMM1_RS05160	COG2201	protein-glutamate methylesterase activity
BbuMM1_RS05210	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BbuMM1_RS05230	COG0835	chemotaxis
BbuMM1_RS05240	COG2198	Histidine kinase
BbuMM1_RS05240	COG0643	Histidine kinase
BbuMM1_RS05255	COG0745	RESPONSE REGULATOR receiver
BbuMM1_RS05265	COG0528	UMP kinase activity
BbuMM1_RS05270	COG1215	transferase activity, transferring glycosyl groups
BbuMM1_RS05275	COG1121	(ABC) transporter
BbuMM1_RS05300	COG3290	protein histidine kinase activity
BbuMM1_RS05300	COG0840	transmembrane signaling receptor activity
BbuMM1_RS05325	COG0534	Mate efflux family protein
BbuMM1_RS05345	COG2348	transferase activity, transferring amino-acyl groups
BbuMM1_RS05355	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BbuMM1_RS05370	COG2333	competence protein COMEC
BbuMM1_RS05370	COG0658	competence protein
BbuMM1_RS05380	COG1022	Amp-dependent synthetase and ligase
BbuMM1_RS05395	COG0840	transmembrane signaling receptor activity
BbuMM1_RS05400	COG5278	phosphoserine phosphatase activity
BbuMM1_RS05400	COG0840	transmembrane signaling receptor activity
BbuMM1_RS05425	COG0484	heat shock protein binding
BbuMM1_RS05435	COG1620	l-lactate permease
BbuMM1_RS05440	COG1686	Belongs to the peptidase S11 family
BbuMM1_RS05450	COG0210	DNA helicase
BbuMM1_RS05455	COG2195	Cleaves the N-terminal amino acid of tripeptides
BbuMM1_RS05525	COG0295	cytidine deaminase activity
BbuMM1_RS05565	COG0791	NLP P60 protein
BbuMM1_RS05565	COG1388	LysM domain
BbuMM1_RS05565	COG3103	Sh3 type 3 domain protein
BbuMM1_RS05590	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BbuMM1_RS05590	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BbuMM1_RS05590	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BbuMM1_RS05610	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BbuMM1_RS05625	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BbuMM1_RS05640	COG1757	Na H antiporter
BbuMM1_RS05650	COG1177	transmembrane transport
BbuMM1_RS05655	COG1176	ABC-type spermidine putrescine transport system, permease component I
BbuMM1_RS05665	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BbuMM1_RS05675	COG2190	(PTS) system
BbuMM1_RS05675	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BbuMM1_RS05675	COG1263	PTS System
BbuMM1_RS05725	COG0484	heat shock protein binding
BbuMM1_RS05730	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BbuMM1_RS05780	COG0860	N-Acetylmuramoyl-L-alanine amidase
BbuMM1_RS05800	COG0835	chemotaxis
BbuMM1_RS05810	COG2201	protein-glutamate methylesterase activity
BbuMM1_RS05835	COG3845	ABC transporter
BbuMM1_RS05840	COG4603	Belongs to the binding-protein-dependent transport system permease family
BbuMM1_RS05845	COG1079	Belongs to the binding-protein-dependent transport system permease family
BbuMM1_RS05850	COG0840	transmembrane signaling receptor activity
BbuMM1_RS05855	COG0840	transmembrane signaling receptor activity
BbuMM1_RS05865	COG3425	synthase
BbuMM1_RS05905	COG0783	Belongs to the Dps family
BbuMM1_RS05920	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BbuMM1_RS05975	COG0617	tRNA 3'-terminal CCA addition
BbuMM1_RS06000	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BbuMM1_RS06030	COG1077	Cell shape determining protein MreB Mrl
BbuMM1_RS06045	COG0768	penicillin binding
BbuMM1_RS06050	COG0772	Belongs to the SEDS family
BbuMM1_RS06060	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BbuMM1_RS06075	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BbuMM1_RS06085	COG0003	Pfam Anion-transporting ATPase
BbuMM1_RS06095	COG0446	pyridine nucleotide-disulphide oxidoreductase
BbuMM1_RS06110	COG1475	DNA binding
BbuMM1_RS06125	COG0009	L-threonylcarbamoyladenylate synthase
BbuMM1_RS06130	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BbuMM1_RS06150	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
BbuMM1_RS06150	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BbuMM1_RS06160	COG0488	(ABC) transporter
BbuMM1_RS06185	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BbuMM1_RS06190	COG4239	(ABC) transporter, permease
BbuMM1_RS06195	COG4168	peptide transport system, permease
BbuMM1_RS06225	COG1131	(ABC) transporter
BbuMM1_RS06235	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BbuMM1_RS06265	COG0739	heme binding
BbuMM1_RS06270	COG2204	response regulator
BbuMM1_RS06275	COG5002	protein histidine kinase activity
BbuMM1_RS06280	COG0470	DNA polymerase III
BbuMM1_RS06310	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BbuMM1_RS06430	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BbuMM1_RS06440	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BbuMM1_RS06455	COG1040	competence protein
BbuMM1_RS06535	COG4145	pantothenate transmembrane transporter activity
BbuMM1_RS06540	COG0564	pseudouridine synthase activity
BbuMM1_RS06555	COG1561	YicC-like family, N-terminal region
BbuMM1_RS06610	COG0419	ATPase involved in DNA repair
BbuMM1_RS06615	COG1940	carbohydrate kinase activity
BbuMM1_RS06635	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BbuMM1_RS06680	COG1288	antiporter activity
